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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor
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Accession:CHEBI:147285 term browser browse the term
Definition:An EC 3.4.22.* (cysteine endopeptidase) inhibitor that interferes with the action of SARS coronavirus main proteinase (EC 3.4.22.69).
Synonyms:related_synonym: 3C-like protease inhibitor;   3C-like protease inhibitors;   3cLpro inhibitor;   3cLpro inhibitors;   EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitors;   EC 3.4.22.69 inhibitor;   EC 3.4.22.69 inhibitors;   Mpro inhibitor;   Mpro inhibitors;   SARS 3C-like protease inhibitor;   SARS 3C-like protease inhibitors;   SARS coronavirus 3CL protease inhibitor;   SARS coronavirus 3CL protease inhibitors;   SARS coronavirus main peptidase inhibitor;   SARS coronavirus main peptidase inhibitors;   SARS coronavirus main protease inhibitor;   SARS coronavirus main protease inhibitors;   SARS coronavirus main proteinase inhibitor;   SARS coronavirus main proteinase inhibitors;   SARS-CoV 3CLpro enzyme inhibitor;   SARS-CoV 3CLpro enzyme inhibitors;   SARS-CoV Mpro inhibitor;   SARS-CoV Mpro inhibitors;   SARS-CoV main protease inhibitor;   SARS-CoV main protease inhibitors;   coronavirus 3C-like protease inhibitor;   coronavirus 3C-like protease inhibitors;   severe acute respiratory syndrome coronavirus main protease inhibitor;   severe acute respiratory syndrome coronavirus main protease inhibitors
 xref: Wikipedia:C30_Endopeptidase



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5,6,7-trimethoxyflavone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO 5,6,7-trimethoxyflavone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the localization of FOS protein] CTD PMID:24161485 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO 5,6,7-trimethoxyflavone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL1B mRNA]; 5,6,7-trimethoxyflavone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL1B protein] CTD PMID:24161485 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO 5,6,7-trimethoxyflavone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA]; 5,6,7-trimethoxyflavone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 protein] CTD PMID:24161485 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO 5,6,7-trimethoxyflavone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the localization of JUN protein] CTD PMID:24161485 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO 5,6,7-trimethoxyflavone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of and results in increased degradation of NFKBIA protein] CTD PMID:24161485 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO 5,6,7-trimethoxyflavone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA]; 5,6,7-trimethoxyflavone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 protein]; [5,6,7-trimethoxyflavone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 protein]] which results in decreased abundance of Nitric Oxide CTD PMID:24161485 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO 5,6,7-trimethoxyflavone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 mRNA]; 5,6,7-trimethoxyflavone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 protein]; [5,6,7-trimethoxyflavone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 protein]] which results in decreased abundance of Dinoprostone CTD PMID:24161485 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO 5,6,7-trimethoxyflavone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the localization of RELA protein] CTD PMID:24161485 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO 5,6,7-trimethoxyflavone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the localization of STAT1 protein]; 5,6,7-trimethoxyflavone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of STAT1 protein] CTD PMID:24161485 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO 5,6,7-trimethoxyflavone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the localization of STAT3 protein]; 5,6,7-trimethoxyflavone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of STAT3 protein] CTD PMID:24161485 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 5,6,7-trimethoxyflavone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF mRNA]; 5,6,7-trimethoxyflavone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein] CTD PMID:24161485 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
baicalein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression
multiple interactions
increases activity
ISO baicalein results in increased expression of ABCB1 protein
baicalein inhibits the reaction [ABCB1 protein results in decreased uptake of Daunorubicin]; baicalein inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]; baicalein inhibits the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Daunorubicin]]; baicalein promotes the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]]
baicalein results in increased activity of ABCB1 protein
CTD PMID:34217736 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 decreases activity ISO baicalein results in decreased activity of ABCC1 protein CTD PMID:15670588 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Acta2 actin alpha 2, smooth muscle decreases expression
multiple interactions
ISO baicalein results in decreased expression of ACTA2 protein
baicalein inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; baicalein inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; MIR21 mRNA inhibits the reaction [baicalein inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]]; SPRY1 protein affects the reaction [baicalein inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]]
CTD PMID:30201452 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Afp alpha-fetoprotein affects binding EXP baicalein binds to AFP protein CTD PMID:23013281 PMID:25349334 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
affects response to substance
increases activity
increases expression
ISO AHR protein affects the reaction [baicalein results in decreased phosphorylation of RB1 protein]; baicalein binds to and results in increased activity of AHR protein
AHR protein affects the susceptibility to baicalein
baicalein results in increased activity of AHR protein
baicalein results in increased expression of AHR protein
CTD PMID:14644660 PMID:17869316 PMID:22820424 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions ISO 5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin affects the expression of and affects the localization of AIFM1 protein]]; baicalein inhibits the reaction [Bleomycin affects the expression of and affects the localization of AIFM1 protein] CTD PMID:37783230 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
affects binding
increases phosphorylation
multiple interactions
ISO baicalein results in decreased phosphorylation of AKT1 protein
baicalein binds to AKT1 protein
baicalein results in increased phosphorylation of AKT1 protein
baicalein inhibits the reaction [Cholesterol, LDL analog results in increased expression of AKT1 mRNA]; Lithium Chloride inhibits the reaction [baicalein results in decreased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [baicalein results in increased phosphorylation of AKT1 protein]
CTD PMID:18025287 PMID:22820424 PMID:36988316 PMID:38230788 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type multiple interactions
decreases activity
ISO baicalein inhibits the reaction [ALOX12 protein results in increased chemical synthesis of 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid]
baicalein results in decreased activity of ALOX12 protein
CTD PMID:17027136 PMID:23238474 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542
JBrowse link
G Alox15 arachidonate 15-lipoxygenase decreases activity ISO baicalein results in decreased activity of ALOX15 protein CTD PMID:23238474 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874
JBrowse link
G App amyloid beta precursor protein multiple interactions EXP baicalein inhibits the reaction [APP protein binds to APP protein] CTD PMID:17323972 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Ascl3 achaete-scute family bHLH transcription factor 3 affects expression ISO baicalein affects the expression of ASCL3 protein CTD PMID:36055377 NCBI chr 1:163,755,306...163,755,951
Ensembl chr 1:163,754,956...163,759,682
JBrowse link
G Ascl4 achaete-scute family bHLH transcription factor 4 affects expression ISO baicalein affects the expression of ASCL4 protein CTD PMID:36055377 NCBI chr 7:17,940,972...17,943,215
Ensembl chr 7:17,941,709...17,942,146
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
ISO 5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in increased expression of BAX protein]]; baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of BAX protein modified form]; baicalein inhibits the reaction [Bleomycin results in increased expression of BAX protein]
baicalein results in increased expression of BAX protein
CTD PMID:20850421 PMID:21457722 PMID:37783230 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
ISO 5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in decreased expression of BCL2 protein]]; baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in decreased expression of BCL2 protein modified form]; baicalein inhibits the reaction [Bleomycin results in decreased expression of BCL2 protein]
baicalein results in decreased expression of BCL2 protein
MIR3663 mRNA promotes the reaction [baicalein results in decreased expression of BCL2 protein]
CTD PMID:20850421 PMID:33838155 PMID:37783230 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
decreases expression
ISO SB 203580 inhibits the reaction [baicalein results in decreased expression of BIRC5 protein]; wortmannin promotes the reaction [baicalein results in decreased expression of BIRC5 protein] CTD PMID:18025287 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Casp3 caspase 3 multiple interactions ISO 5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in increased cleavage of CASP3 protein]]; baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of CASP3 protein modified form]; baicalein inhibits the reaction [Bleomycin results in increased cleavage of CASP3 protein] CTD PMID:20850421 PMID:37783230 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions ISO baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of CASP8 protein modified form] CTD PMID:20850421 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO baicalein results in decreased expression of CCNA2 protein CTD PMID:21457722 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO baicalein results in decreased expression of CCNB1 protein CTD PMID:18025287 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression
increases expression
ISO Lithium Chloride inhibits the reaction [baicalein results in decreased expression of CCND1 protein]; N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalein results in increased expression of CCND1 mRNA] CTD PMID:19160421 PMID:21457722 PMID:22820424 PMID:24560969 PMID:36988316 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO baicalein results in decreased expression of CCNE1 protein CTD PMID:24560969 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases phosphorylation
multiple interactions
ISO baicalein results in decreased phosphorylation of CDK1 protein
SB 203580 inhibits the reaction [baicalein results in decreased phosphorylation of CDK1 protein]; wortmannin promotes the reaction [baicalein results in decreased phosphorylation of CDK1 protein]
CTD PMID:18025287 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk4 cyclin-dependent kinase 4 increases expression ISO baicalein results in increased expression of CDK4 protein CTD PMID:22820424 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO baicalein inhibits the reaction [Mitomycin results in increased expression of CDKN1A protein] CTD PMID:34624459 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression ISO baicalein results in decreased expression of CEBPA protein CTD PMID:24560969 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta decreases expression ISO baicalein results in decreased expression of CEBPB mRNA CTD PMID:24560969 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma decreases expression ISO baicalein results in decreased expression of CEBPG mRNA CTD PMID:24560969 NCBI chr 1:87,683,060...87,692,772
Ensembl chr 1:87,684,019...87,694,569
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator multiple interactions ISO baicalein inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of CFLAR protein] CTD PMID:20850421 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Cftr CF transmembrane conductance regulator increases activity ISO baicalein results in increased activity of CFTR protein CTD PMID:15234961 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO baicalein inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]
5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]]; baicalein inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]
CTD PMID:30201452 PMID:37783230 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col1a2 collagen type I alpha 2 chain multiple interactions EXP baicalein inhibits the reaction [TGFB1 protein results in increased expression of COL1A2 mRNA] CTD PMID:19474275 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
JBrowse link
G Csf2 colony stimulating factor 2 decreases expression ISO baicalein results in decreased expression of CSF2 mRNA CTD PMID:10718847 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] affects the localization of CYCS protein] CTD PMID:20850421 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
decreases expression
multiple interactions
increases chemical synthesis
decreases activity
ISO baicalein results in increased expression of CYP1A1 protein
baicalein results in decreased expression of CYP1A1 mRNA
[CYP1A1 protein results in increased metabolism of chrysin] which results in increased chemical synthesis of baicalein; baicalein inhibits the reaction [benz(a)anthracene results in increased expression of CYP1A1 mRNA]; baicalein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
CYP1A1 protein results in increased chemical synthesis of baicalein
baicalein results in decreased activity of CYP1A1 protein
CTD PMID:12224597 PMID:14644660 PMID:18451504 PMID:19666078 PMID:21053930 More... NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity
increases chemical synthesis
multiple interactions
ISO baicalein results in decreased activity of CYP1A2 protein
CYP1A2 protein results in increased chemical synthesis of baicalein
[CYP1A2 protein results in increased metabolism of chrysin] which results in increased chemical synthesis of baicalein
CTD PMID:19666078 PMID:21053930 PMID:29753067 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity
increases chemical synthesis
multiple interactions
ISO baicalein results in decreased activity of CYP1B1 protein
CYP1B1 protein results in increased chemical synthesis of baicalein
[CYP1B1 protein results in increased metabolism of chrysin] which results in increased chemical synthesis of baicalein; baicalein binds to and results in decreased activity of CYP1B1 protein; baicalein inhibits the reaction [benz(a)anthracene results in increased expression of CYP1B1 mRNA]
CTD PMID:12224597 PMID:19666078 PMID:21053930 PMID:21482471 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO baicalein results in increased expression of CYP2B6 mRNA CTD PMID:25625231 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases activity ISO baicalein results in decreased activity of CYP2C19 protein CTD PMID:29753067 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity ISO baicalein results in decreased activity of CYP2E1 protein CTD PMID:29753067 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity ISO baicalein results in decreased activity of CYP3A4 protein CTD PMID:21053930 PMID:29753067 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 decreases expression ISO baicalein results in decreased expression of DGAT1 protein CTD PMID:24560969 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 increases expression ISO baicalein results in increased expression of DLK1 mRNA CTD PMID:24560969 NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522
JBrowse link
G Egf epidermal growth factor multiple interactions ISO baicalein inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; baicalein inhibits the reaction [EGF protein results in increased phosphorylation of ELK1 protein] CTD PMID:25625231 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
affects binding
decreases phosphorylation
ISO baicalein inhibits the reaction [Cholesterol, LDL analog results in increased expression of EGFR mRNA]; baicalein inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; MIR3663 mRNA promotes the reaction [baicalein results in decreased phosphorylation of EGFR protein]
baicalein binds to EGFR protein
CTD PMID:25625231 PMID:33838155 PMID:38230788 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egr2 early growth response 2 decreases expression ISO baicalein results in decreased expression of EGR2 mRNA CTD PMID:24560969 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
JBrowse link
G Elk1 ETS transcription factor ELK1 multiple interactions ISO baicalein inhibits the reaction [EGF protein results in increased phosphorylation of ELK1 protein] CTD PMID:25625231 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713
JBrowse link
G Epo erythropoietin increases expression ISO baicalein results in increased expression of EPO mRNA CTD PMID:37348668 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions
decreases expression
ISO baicalein results in decreased expression of and results in decreased phosphorylation of ERBB2 protein
baicalein results in decreased expression of ERBB2 mRNA
CTD PMID:36988316 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Esr1 estrogen receptor 1 affects binding
multiple interactions
ISO baicalein binds to ESR1 protein
baicalein inhibits the reaction [Cholesterol, LDL analog results in decreased expression of ESR1 mRNA]
CTD PMID:38230788 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Fabp4 fatty acid binding protein 4 decreases expression ISO baicalein results in decreased expression of FABP4 protein CTD PMID:24560969 NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Fasn fatty acid synthase decreases expression ISO baicalein results in decreased expression of FASN protein CTD PMID:24560969 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO baicalein inhibits the reaction [TGFB1 protein results in increased expression of FN1 protein] CTD PMID:30201452 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Glb1 galactosidase, beta 1 multiple interactions ISO baicalein inhibits the reaction [Mitomycin results in increased activity of GLB1 protein] CTD PMID:34624459 NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127
JBrowse link
G Gli1 GLI family zinc finger 1 decreases expression ISO baicalein results in decreased expression of GLI1 mRNA; baicalein results in decreased expression of GLI1 protein CTD PMID:20395211 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 decreases expression ISO baicalein results in decreased expression of GPAT3 protein CTD PMID:24560969 NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
JBrowse link
G Gpx4 glutathione peroxidase 4 affects expression
multiple interactions
ISO baicalein affects the expression of GPX4 protein
baicalein inhibits the reaction [Polymyxin B results in decreased expression of GPX4 protein]; SIRT1 protein promotes the reaction [baicalein inhibits the reaction [Polymyxin B results in decreased expression of GPX4 protein]]
CTD PMID:36055377 PMID:37354967 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation
multiple interactions
ISO baicalein results in decreased phosphorylation of GSK3B protein
baicalein inhibits the reaction [Mitomycin results in increased phosphorylation of GSK3B protein]
CTD PMID:22820424 PMID:34624459 PMID:36988316 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Hes1 hes family bHLH transcription factor 1 multiple interactions
increases expression
ISO N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalein results in increased expression of HES1 mRNA] CTD PMID:19160421 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 multiple interactions
increases expression
ISO N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalein results in increased expression of HEY1 mRNA] CTD PMID:19160421 NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312
JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 multiple interactions
increases expression
ISO N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalein results in increased expression of HEY2 mRNA] CTD PMID:19160421 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression
ISO baicalein results in decreased degradation of and results in increased expression of HIF1A protein modified form
baicalein results in increased expression of HIF1A mRNA; baicalein results in increased expression of HIF1A protein
CTD PMID:37348668 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO baicalein results in increased expression of HMOX1 mRNA; baicalein results in increased expression of HMOX1 protein
baicalein inhibits the reaction [Polymyxin B results in decreased expression of HMOX1 protein]; baicalein inhibits the reaction [Polymyxin B results in increased expression of HMOX1 protein]; SIRT1 protein promotes the reaction [baicalein inhibits the reaction [Polymyxin B results in decreased expression of HMOX1 protein]]
Hemin promotes the reaction [baicalein results in increased expression of HMOX1 protein]; HMOX1 protein promotes the reaction [baicalein inhibits the reaction [Lipopolysaccharides results in increased activity of NOS2 protein]]
CTD PMID:14563492 PMID:37354967 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 multiple interactions
increases activity
ISO 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid inhibits the reaction [baicalein results in increased activity of HSD11B2 protein] CTD PMID:18032417 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO baicalein inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased expression of JUN protein] CTD PMID:17458902 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO baicalein inhibits the reaction [Benzo(a)pyrene results in increased expression of IL1B protein]
baicalein inhibits the reaction [Cholesterol, LDL analog results in increased expression of IL1B protein]
CTD PMID:22369883 PMID:38230788 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO baicalein inhibits the reaction [Cholesterol, LDL analog results in increased expression of IL6 protein] CTD PMID:38230788 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins2 insulin 2 multiple interactions
increases secretion
ISO baicalein promotes the reaction [Glucose results in increased secretion of INS protein]
baicalein results in increased secretion of INS protein
CTD PMID:17192482 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
affects binding
ISO baicalein inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased expression of JUN protein]; baicalein inhibits the reaction [Cholesterol, LDL analog results in increased expression of JUN mRNA]
baicalein binds to JUN protein
CTD PMID:17458902 PMID:38230788 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Klf2 KLF transcription factor 2 increases expression ISO baicalein results in increased expression of KLF2 mRNA CTD PMID:24560969 NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944
JBrowse link
G Klf5 KLF transcription factor 5 decreases expression ISO baicalein results in decreased expression of KLF5 mRNA CTD PMID:24560969 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445
JBrowse link
G Lpin1 lipin 1 decreases expression ISO baicalein results in decreased expression of LPIN1 protein CTD PMID:24560969 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
affects binding
decreases phosphorylation
ISO baicalein inhibits the reaction [Cholesterol, LDL analog results in increased expression of MAPK1 mRNA]; baicalein results in decreased phosphorylation of and results in decreased activity of MAPK1 protein; MIR3663 mRNA promotes the reaction [baicalein results in decreased phosphorylation of MAPK1 protein]
baicalein binds to MAPK1 protein
baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of MAPK1 protein modified form]; baicalein inhibits the reaction [PLA2G2A protein results in increased phosphorylation of MAPK1 protein]
CTD PMID:10718847 PMID:20850421 PMID:31811862 PMID:33838155 PMID:38230788 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases phosphorylation
ISO baicalein results in decreased phosphorylation of and results in decreased activity of MAPK3 protein; MIR3663 mRNA promotes the reaction [baicalein results in decreased phosphorylation of MAPK3 protein]
baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of MAPK3 protein modified form]; baicalein inhibits the reaction [PLA2G2A protein results in increased phosphorylation of MAPK3 protein]
CTD PMID:10718847 PMID:20850421 PMID:31811862 PMID:33838155 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO baicalein results in decreased phosphorylation of and results in decreased activity of MAPK8 protein CTD PMID:10718847 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mir1224 microRNA 1224 increases expression ISO baicalein results in increased expression of MIR1224 mRNA CTD PMID:33838155 NCBI chr11:80,306,902...80,306,986
Ensembl chr11:80,306,902...80,306,986
JBrowse link
G Mir21 microRNA 21 multiple interactions ISO baicalein inhibits the reaction [TGFB1 protein results in increased expression of MIR21 mRNA]; MIR21 mRNA inhibits the reaction [baicalein inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]] CTD PMID:30201452 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mir322 microRNA 322 increases expression ISO baicalein results in increased expression of MIR424 mRNA CTD PMID:33838155 NCBI chr  X:132,806,594...132,806,688
Ensembl chr  X:132,806,594...132,806,688
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases activity
multiple interactions
ISO baicalein results in decreased activity of MMP2 protein
baicalein inhibits the reaction [Benzo(a)pyrene results in increased expression of MMP2 mRNA]
CTD PMID:21803068 PMID:22369883 PMID:36988316 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases activity
ISO baicalein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]
baicalein inhibits the reaction [Benzo(a)pyrene results in increased expression of MMP9 mRNA]
baicalein results in decreased activity of MMP9 protein
CTD PMID:19804834 PMID:21803068 PMID:22369883 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO baicalein inhibits the reaction [[Ethanol co-treated with Hydrochloric Acid] results in increased activity of MPO protein] CTD PMID:27780710 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO baicalein results in decreased phosphorylation of and results in decreased activity of MTOR protein CTD PMID:24560969 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Nat1 N-acetyltransferase 1 decreases expression ISO baicalein results in decreased expression of NAT1 mRNA; baicalein results in decreased expression of NAT1 protein CTD PMID:15796204 NCBI chr16:22,218,217...22,238,516
Ensembl chr16:22,208,194...22,238,520
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 decreases localization ISO baicalein results in decreased localization of NFKB1 protein CTD PMID:21803068 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
decreases phosphorylation
ISO baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in decreased expression of NFKBIA protein]
baicalein results in decreased phosphorylation of NFKBIA protein
CTD PMID:20850421 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfkbib NFKB inhibitor beta decreases phosphorylation ISO baicalein results in decreased phosphorylation of NFKBIB protein CTD PMID:21803068 NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases expression
ISO baicalein inhibits the reaction [Benzo(a)pyrene results in increased expression of NOS2 protein]; baicalein inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Hemin promotes the reaction [baicalein inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; HMOX1 protein promotes the reaction [baicalein inhibits the reaction [Lipopolysaccharides results in increased activity of NOS2 protein]]; tin protoporphyrin IX inhibits the reaction [baicalein inhibits the reaction [Lipopolysaccharides results in increased activity of NOS2 protein]]
baicalein results in decreased expression of NOS2 protein
CTD PMID:14563492 PMID:20850421 PMID:22369883 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Notch1 notch receptor 1 increases activity
increases expression
ISO baicalein results in increased activity of NOTCH1 protein
baicalein results in increased expression of NOTCH1 mRNA
CTD PMID:19160421 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 affects localization ISO baicalein affects the localization of NR1I3 protein CTD PMID:25625231 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha affects binding
multiple interactions
ISO baicalein binds to PIK3CA protein
baicalein inhibits the reaction [Cholesterol, LDL analog results in increased expression of PIK3CA mRNA]
CTD PMID:38230788 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Pkm pyruvate kinase M1/2 increases activity ISO baicalein results in increased activity of PKM protein CTD PMID:25388478 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
JBrowse link
G Pla2g2a phospholipase A2 group IIA multiple interactions ISO baicalein inhibits the reaction [PLA2G2A protein results in increased expression of PTGS2 protein]; baicalein inhibits the reaction [PLA2G2A protein results in increased phosphorylation of MAPK1 protein]; baicalein inhibits the reaction [PLA2G2A protein results in increased phosphorylation of MAPK3 protein] CTD PMID:31811862 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
JBrowse link
G Plau plasminogen activator, urokinase decreases activity ISO baicalein results in decreased activity of PLAU protein CTD PMID:21803068 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 multiple interactions ISO baicalein inhibits the reaction [Fenretinide results in increased expression of PMAIP1 mRNA] CTD PMID:17216584 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression ISO baicalein results in decreased expression of PPARG protein CTD PMID:24560969 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Prkca protein kinase C, alpha decreases phosphorylation ISO baicalein results in decreased phosphorylation of PRKCA protein CTD PMID:21803068 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO baicalein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]
baicalein inhibits the reaction [Benzo(a)pyrene results in increased expression of PTGS2 mRNA]; baicalein inhibits the reaction [PLA2G2A protein results in increased expression of PTGS2 protein]; baicalein inhibits the reaction [Polymyxin B results in increased expression of PTGS2 protein]
CTD PMID:19804834 PMID:22369883 PMID:31811862 PMID:37354967 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Pygb glycogen phosphorylase B decreases activity ISO baicalein results in decreased activity of PYGB protein CTD PMID:37277066 NCBI chr 3:139,611,724...139,658,521
Ensembl chr 3:139,611,749...139,663,553
JBrowse link
G Pygl glycogen phosphorylase L decreases activity ISO baicalein results in decreased activity of PYGL protein CTD PMID:37277066 NCBI chr 6:88,697,598...88,740,260
Ensembl chr 6:88,697,593...88,740,310
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions
decreases phosphorylation
ISO AHR protein affects the reaction [baicalein results in decreased phosphorylation of RB1 protein]; Lithium Chloride inhibits the reaction [baicalein results in decreased phosphorylation of RB1 protein] CTD PMID:22820424 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
decreases phosphorylation
affects localization
decreases localization
ISO baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] affects the localization of RELA protein]; baicalein inhibits the reaction [Benzo(a)pyrene results in increased expression of RELA protein]
baicalein results in decreased phosphorylation of RELA protein
MIR3663 mRNA promotes the reaction [baicalein results in decreased phosphorylation of RELA protein]; NKILA mRNA promotes the reaction [baicalein affects the localization of RELA protein]
baicalein results in decreased localization of RELA protein
CTD PMID:20850421 PMID:21803068 PMID:22369883 PMID:29481769 PMID:33838155 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions ISO baicalein results in decreased phosphorylation of and results in decreased activity of RPS6KB1 protein CTD PMID:24560969 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Sh3gl1 SH3 domain containing GRB2 like 1, endophilin A2 decreases expression
multiple interactions
ISO baicalein results in decreased expression of SH3GL1 mRNA; baicalein results in decreased expression of SH3GL1 protein
MIR3663 mRNA promotes the reaction [baicalein results in decreased expression of SH3GL1 protein]
CTD PMID:33838155 NCBI chr 9:842,285...869,753
Ensembl chr 9:842,288...869,716
JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO baicalein inhibits the reaction [Polymyxin B results in decreased expression of SIRT1 protein]; SIRT1 protein promotes the reaction [baicalein inhibits the reaction [Polymyxin B results in decreased expression of GPX4 protein]]; SIRT1 protein promotes the reaction [baicalein inhibits the reaction [Polymyxin B results in decreased expression of HMOX1 protein]]; SIRT1 protein promotes the reaction [baicalein inhibits the reaction [Polymyxin B results in decreased expression of SLC7A11 protein]]; SIRT1 protein promotes the reaction [baicalein inhibits the reaction [Polymyxin B results in increased acetylation of TP53 protein]] CTD PMID:37354967 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc22a6 solute carrier family 22 member 6 decreases activity ISO baicalein results in decreased activity of SLC22A6 protein CTD PMID:32159797 NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173
JBrowse link
G Slc7a11 solute carrier family 7 member 11 multiple interactions ISO baicalein inhibits the reaction [Polymyxin B results in decreased expression of SLC7A11 protein]; SIRT1 protein promotes the reaction [baicalein inhibits the reaction [Polymyxin B results in decreased expression of SLC7A11 protein]] CTD PMID:37354967 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
G Snca synuclein alpha multiple interactions ISO baicalein inhibits the reaction [SNCA protein binds to SNCA protein]
baicalein inhibits the reaction [Rotenone promotes the reaction [SNCA protein binds to SNCA protein]]; baicalein inhibits the reaction [Rotenone results in increased expression of SNCA protein]
CTD PMID:27425033 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 multiple interactions ISO baicalein inhibits the reaction [TGFB1 protein results in decreased expression of SPRY1 protein]; SPRY1 protein affects the reaction [baicalein inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]] CTD PMID:30201452 NCBI chr 2:120,557,256...120,561,917
Ensembl chr 2:120,556,706...120,566,189
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase affects binding
multiple interactions
ISO baicalein binds to SRC protein
baicalein inhibits the reaction [Cholesterol, LDL analog results in increased expression of SRC mRNA]
CTD PMID:38230788 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression ISO baicalein results in decreased expression of SREBF1 protein CTD PMID:24560969 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO baicalein inhibits the reaction [TGFB1 protein results in increased phosphorylation of STAT3 protein] CTD PMID:30201452 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP
ISO
baicalein inhibits the reaction [TGFB1 protein results in increased expression of COL1A2 mRNA]
5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]]
baicalein inhibits the reaction [TGFB1 protein results in decreased expression of SPRY1 protein]; baicalein inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; baicalein inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; baicalein inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]; baicalein inhibits the reaction [TGFB1 protein results in increased expression of FN1 protein]; baicalein inhibits the reaction [TGFB1 protein results in increased expression of MIR21 mRNA]; baicalein inhibits the reaction [TGFB1 protein results in increased phosphorylation of STAT3 protein]; MIR21 mRNA inhibits the reaction [baicalein inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]]; SPRY1 protein affects the reaction [baicalein inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]]
CTD PMID:19474275 PMID:30201452 PMID:37783230 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Th tyrosine hydroxylase multiple interactions ISO baicalein inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:27425033 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Tnf tumor necrosis factor decreases expression
multiple interactions
ISO baicalein results in decreased expression of TNF protein
baicalein inhibits the reaction [Cholesterol, LDL analog results in increased expression of TNF protein]
baicalein inhibits the reaction [Benzo(a)pyrene results in increased expression of TNF protein]
CTD PMID:20850421 PMID:22369883 PMID:38230788 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 increases expression
affects binding
multiple interactions
ISO baicalein results in increased expression of TP53 protein
baicalein binds to TP53 protein
baicalein inhibits the reaction [Cholesterol, LDL analog results in increased expression of TP53 mRNA]; baicalein inhibits the reaction [Polymyxin B results in increased acetylation of TP53 protein]; SIRT1 protein promotes the reaction [baicalein inhibits the reaction [Polymyxin B results in increased acetylation of TP53 protein]]
CTD PMID:21457722 PMID:37354967 PMID:38230788 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO baicalein results in decreased expression of VEGFA protein CTD PMID:16638750 PMID:36988316 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Xdh xanthine dehydrogenase multiple interactions ISO baicalein inhibits the reaction [[Biological Products co-treated with potassium oxonate] results in increased activity of XDH protein] CTD PMID:34044073 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
JBrowse link
G Xiap X-linked inhibitor of apoptosis multiple interactions ISO baicalein inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in decreased activity of XIAP protein] CTD PMID:20850421 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700
JBrowse link
baicalin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions
increases expression
EXP baicalin results in increased expression of and results in increased activity of ACHE protein
baicalin results in increased expression of ACHE mRNA
CTD PMID:27019979 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Ahr aryl hydrocarbon receptor increases activity ISO baicalin results in increased activity of AHR protein CTD PMID:17869316 PMID:26204831 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Aif1 allograft inflammatory factor 1 multiple interactions ISO baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of AIF1 protein] CTD PMID:38016618 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions EXP baicalin inhibits the reaction [Hydrogen Peroxide affects the localization of and results in increased activity of ALOX5 protein] CTD PMID:20139896 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Angpt1 angiopoietin 1 multiple interactions EXP baicalin inhibits the reaction [Streptozocin results in decreased expression of ANGPT1 mRNA] CTD PMID:34414639 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions EXP baicalin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of ATF2 protein] CTD PMID:24312512 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO
EXP
baicalin results in increased expression of BAX protein
baicalin affects the reaction [Rotenone results in increased expression of BAX mRNA]; baicalin inhibits the reaction [Rotenone results in increased expression of BAX protein]
baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]; baicalin inhibits the reaction [Gentamicins results in increased expression of BAX mRNA]; baicalin inhibits the reaction [Gentamicins results in increased expression of BAX protein]
baicalin inhibits the reaction [Rotenone affects the expression of BAX protein]
CTD PMID:21457722 PMID:25423838 PMID:31021006 PMID:34333357 PMID:36446982 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
EXP
ISO
baicalin inhibits the reaction [Rotenone affects the expression of BCL2 protein]
baicalin results in decreased expression of BCL2 protein
baicalin affects the reaction [Rotenone results in decreased expression of BCL2 mRNA]; baicalin inhibits the reaction [Rotenone results in decreased expression of BCL2 protein]
baicalin inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; baicalin inhibits the reaction [Gentamicins results in decreased expression of BCL2 mRNA]; baicalin inhibits the reaction [Gentamicins results in decreased expression of BCL2 protein]
CTD PMID:25423838 PMID:31021006 PMID:34333357 PMID:36446982 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Casp1 caspase 1 multiple interactions ISO baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of CASP1 protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of CASP1 protein]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of CASP1 protein]] CTD PMID:38016618 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 multiple interactions EXP
ISO
baicalin inhibits the reaction [Rotenone affects the expression of CASP3 protein]
baicalin affects the reaction [Rotenone results in decreased activity of CASP3 protein]
baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein]; baicalin inhibits the reaction [Gentamicins results in increased cleavage of CASP3 protein]
CTD PMID:25423838 PMID:31021006 PMID:34333357 PMID:36446982 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase multiple interactions ISO baicalin inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein] CTD PMID:34333357 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO baicalin results in decreased expression of CCNA2 protein CTD PMID:21457722 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnd1 cyclin D1 increases expression
decreases expression
multiple interactions
ISO baicalin results in increased expression of CCND1 mRNA
baicalin results in decreased expression of CCND1 protein
N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalin results in increased expression of CCND1 mRNA]
CTD PMID:19160421 PMID:21457722 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Col1a2 collagen type I alpha 2 chain multiple interactions EXP baicalin inhibits the reaction [TGFB1 protein results in increased expression of COL1A2 mRNA] CTD PMID:19474275 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO 3',4'-dimethoxyflavone inhibits the reaction [baicalin results in increased expression of CYP1A1 mRNA]; 3',4'-dimethoxyflavone inhibits the reaction [baicalin results in increased expression of CYP1A1 protein]; baicalin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
baicalin results in increased expression of CYP1A1 mRNA; baicalin results in increased expression of CYP1A1 protein
CTD PMID:18451504 PMID:26204831 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression
ISO 3',4'-dimethoxyflavone inhibits the reaction [baicalin results in increased expression of CYP1A2 mRNA]; 3',4'-dimethoxyflavone inhibits the reaction [baicalin results in increased expression of CYP1A2 protein]
resveratrol inhibits the reaction [baicalin results in increased expression of CYP1A2 mRNA]; resveratrol inhibits the reaction [baicalin results in increased expression of CYP1A2 protein]
baicalin results in increased expression of CYP1A2 mRNA; baicalin results in increased expression of CYP1A2 protein
CTD PMID:26204831 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Egf epidermal growth factor multiple interactions ISO baicalin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; baicalin inhibits the reaction [EGF protein results in increased phosphorylation of ELK1 protein] CTD PMID:25625231 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO baicalin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:25625231 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Elk1 ETS transcription factor ELK1 multiple interactions ISO baicalin inhibits the reaction [EGF protein results in increased phosphorylation of ELK1 protein] CTD PMID:25625231 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO baicalin inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein] CTD PMID:29031535 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Foxa2 forkhead box A2 decreases expression ISO baicalin results in decreased expression of FOXA2 mRNA; baicalin results in decreased expression of FOXA2 protein CTD PMID:32687838 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions EXP baicalin inhibits the reaction [tert-Butylhydroperoxide results in increased activity of GOT1 protein] CTD PMID:15645217 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP baicalin inhibits the reaction [tert-Butylhydroperoxide results in increased activity of GPT protein] CTD PMID:15645217 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Hes1 hes family bHLH transcription factor 1 increases expression
multiple interactions
ISO baicalin results in increased expression of HES1 mRNA
N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalin results in increased expression of HES1 mRNA]
CTD PMID:19160421 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 increases expression
multiple interactions
ISO baicalin results in increased expression of HEY1 mRNA
N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalin results in increased expression of HEY1 mRNA]
CTD PMID:19160421 NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312
JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 multiple interactions
increases expression
ISO N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalin results in increased expression of HEY2 mRNA] CTD PMID:19160421 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO
EXP
[baicalin co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of HMOX1 protein; baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of HMOX1 protein]; baicalin promotes the reaction [Carbon Tetrachloride results in increased expression of HMOX1 mRNA]; baicalin promotes the reaction [Carbon Tetrachloride results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [[baicalin co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of HMOX1 protein]
baicalin results in increased expression of HMOX1 mRNA; baicalin results in increased expression of HMOX1 protein
CTD PMID:16824337 PMID:18187930 PMID:38016618 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnf1a HNF1 homeobox A multiple interactions
decreases expression
ISO baicalin inhibits the reaction [HNF4A protein binds to HNF1A promoter]; HNF1A protein promotes the reaction [baicalin results in decreased secretion of Hepatitis B Surface Antigens]; HNF4A protein promotes the reaction [baicalin results in decreased expression of HNF1A mRNA]; HNF4A protein promotes the reaction [baicalin results in decreased expression of HNF1A protein]
baicalin results in decreased expression of HNF1A mRNA; baicalin results in decreased expression of HNF1A protein
CTD PMID:32687838 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha decreases expression
multiple interactions
ISO baicalin results in decreased expression of HNF4A protein
baicalin inhibits the reaction [HNF4A protein binds to HNF1A promoter]; HNF4A protein promotes the reaction [baicalin results in decreased expression of HNF1A mRNA]; HNF4A protein promotes the reaction [baicalin results in decreased expression of HNF1A protein]; HNF4A protein promotes the reaction [baicalin results in decreased secretion of Hepatitis B Surface Antigens]
baicalin results in decreased expression of HNF4A mRNA; baicalin results in decreased expression of HNF4A protein
CTD PMID:32687838 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions EXP baicalin inhibits the reaction [Streptozocin results in increased phosphorylation of HSPB1 protein] CTD PMID:34414639 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL1B mRNA]; baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL1B protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL1B mRNA]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL1B protein]; baicalin inhibits the reaction [Palmitic Acid results in increased secretion of IL1B protein]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL1B protein]]
baicalin inhibits the reaction [Rotenone results in increased expression of IL1B protein]
CTD PMID:29031535 PMID:36446982 PMID:38016618 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 decreases expression
multiple interactions
EXP
ISO
baicalin results in decreased expression of IL6 mRNA; baicalin results in decreased expression of IL6 protein
baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL6 mRNA]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL6 mRNA]; baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of IL6 protein]; baicalin inhibits the reaction [Palmitic Acid results in increased secretion of IL6 protein]
CTD PMID:22019745 PMID:29031535 PMID:34333357 PMID:38016618 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins1 insulin 1 multiple interactions EXP baicalin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein] CTD PMID:34414639 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions ISO baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of KEAP1 protein]; baicalin promotes the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in decreased expression of KEAP1 protein] CTD PMID:38016618 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP baicalin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein] CTD PMID:34414639 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP baicalin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein] CTD PMID:34414639 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor decreases expression EXP baicalin results in decreased expression of MYD88 protein CTD PMID:22019745 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO [baicalin co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] affects the localization of NFE2L2 protein; baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of NFE2L2 protein]; baicalin inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased ubiquitination of NFE2L2 protein]; baicalin promotes the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NFE2L2 protein]; baicalin promotes the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NFE2L2 protein]; NFE2L2 protein affects the reaction [[baicalin co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of CASP1 protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL1B protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NLRP3 protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of PYCARD protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased phosphorylation of RELA protein]] CTD PMID:38016618 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression EXP baicalin results in increased expression of NFKBIA protein CTD PMID:22019745 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of NLRP3 protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NLRP3 protein]; baicalin inhibits the reaction [Palmitic Acid results in increased expression of NLRP3 protein]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NLRP3 protein]] CTD PMID:29031535 PMID:38016618 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases expression
EXP
ISO
baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; mifobate inhibits the reaction [baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]]
baicalin results in decreased expression of NOS2 mRNA; baicalin results in decreased expression of NOS2 protein
baicalin inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 mRNA]; baicalin inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 protein]
CTD PMID:18187930 PMID:22019745 PMID:24312512 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Notch1 notch receptor 1 increases activity
increases expression
ISO baicalin results in increased activity of NOTCH1 protein
baicalin results in increased expression of NOTCH1 mRNA
CTD PMID:19160421 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 increases expression ISO Baicalin increases expression of NR1H3 mRNA and protein in foam cells RGD PMID:27389392 RGD:401842390 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
JBrowse link
G Pkm pyruvate kinase M1/2 increases activity ISO baicalin results in increased activity of PKM protein CTD PMID:25388478 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions EXP baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased phosphorylation of and results in decreased activity of PPARG protein] CTD PMID:24312512 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Prima1 proline rich membrane anchor 1 increases expression EXP baicalin results in increased expression of PRIMA1 mRNA CTD PMID:27019979 NCBI chr 6:122,338,365...122,390,955
Ensembl chr 6:122,338,370...122,389,921
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression EXP baicalin results in decreased expression of PTGS2 mRNA; baicalin results in decreased expression of PTGS2 protein CTD PMID:22019745 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Pycard PYD and CARD domain containing multiple interactions ISO baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of PYCARD protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of PYCARD protein]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of PYCARD protein]] CTD PMID:38016618 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP
ISO
baicalin affects the localization of and results in decreased expression of RELA protein
baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased phosphorylation of RELA protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased phosphorylation of RELA protein]; baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of and results in increased phosphorylation of RELA protein]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased phosphorylation of RELA protein]]
CTD PMID:22019745 PMID:34333357 PMID:38016618 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Snca synuclein alpha multiple interactions ISO [baicalin co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] affects the localization of NFE2L2 protein; [baicalin co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of HMOX1 protein; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of CASP1 protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL1B mRNA]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL1B protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL6 mRNA]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NLRP3 protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of PYCARD protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of TNF mRNA]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased phosphorylation of RELA protein]; baicalin inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased ubiquitination of NFE2L2 protein]; baicalin promotes the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in decreased expression of KEAP1 protein]; baicalin promotes the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NFE2L2 protein]; baicalin promotes the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NFE2L2 protein]; NFE2L2 protein affects the reaction [[baicalin co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of CASP1 protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL1B protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NLRP3 protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of PYCARD protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased phosphorylation of RELA protein]] CTD PMID:38016618 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Tek TEK receptor tyrosine kinase multiple interactions EXP baicalin inhibits the reaction [Streptozocin results in decreased expression of TEK mRNA] CTD PMID:34414639 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804
JBrowse link
G Tfam transcription factor A, mitochondrial decreases expression
multiple interactions
ISO baicalin results in decreased expression of TFAM mRNA
baicalin inhibits the reaction [Rotenone results in decreased expression of TFAM mRNA]
CTD PMID:36446982 NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP baicalin inhibits the reaction [Streptozocin results in decreased expression of TGFB1 mRNA]; baicalin inhibits the reaction [TGFB1 protein results in increased expression of COL1A2 mRNA] CTD PMID:19474275 PMID:34414639 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Th tyrosine hydroxylase multiple interactions ISO baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of TH protein] CTD PMID:38016618 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Tlr4 toll-like receptor 4 decreases expression
multiple interactions
EXP
ISO
baicalin results in decreased expression of TLR4 protein
baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of TLR4 protein]
baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]
CTD PMID:22019745 PMID:24312512 PMID:34333357 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
ISO
EXP
baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of TNF mRNA]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of TNF mRNA]; baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of TNF protein]; baicalin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]; baicalin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]
baicalin results in decreased expression of TNF mRNA; baicalin results in decreased expression of TNF protein
baicalin inhibits the reaction [Paraquat results in increased expression of TNF protein]
CTD PMID:16824337 PMID:18187930 PMID:22019745 PMID:34333357 PMID:38016618 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 increases expression ISO baicalin results in increased expression of TP53 protein CTD PMID:21457722 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Txnip thioredoxin interacting protein multiple interactions ISO baicalin inhibits the reaction [Palmitic Acid results in increased expression of TXNIP protein]; dorsomorphin inhibits the reaction [baicalin inhibits the reaction [Palmitic Acid results in increased expression of TXNIP protein]] CTD PMID:29031535 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link
G Usp27x ubiquitin specific peptidase 27, X-linked multiple interactions EXP baicalin inhibits the reaction [Streptozocin results in increased expression of USP27X protein] CTD PMID:34414639 NCBI chr  X:15,123,620...15,126,855
Ensembl chr  X:15,124,596...15,125,912
JBrowse link
G Vegfc vascular endothelial growth factor C multiple interactions EXP baicalin inhibits the reaction [Streptozocin results in decreased expression of VEGFC mRNA] CTD PMID:34414639 NCBI chr16:37,712,251...37,827,845
Ensembl chr16:37,712,262...37,827,848
JBrowse link
G Xdh xanthine dehydrogenase multiple interactions ISO baicalin inhibits the reaction [[Biological Products co-treated with potassium oxonate] results in increased activity of XDH protein] CTD PMID:34044073 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
JBrowse link
ebselen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO ebselen inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein] CTD PMID:16757516 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Adam9 ADAM metallopeptidase domain 9 multiple interactions ISO ebselen inhibits the reaction [Hydrogen Peroxide results in increased expression of ADAM9 protein] CTD PMID:17018608 NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917
JBrowse link
G Afp alpha-fetoprotein multiple interactions EXP ebselen inhibits the reaction [Aflatoxin B1 results in increased expression of AFP mRNA] CTD PMID:11133813 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Alad aminolevulinate dehydratase multiple interactions
decreases activity
EXP
ISO
Dithiothreitol inhibits the reaction [ebselen results in decreased activity of ALAD protein]
ebselen inhibits the reaction [Cadmium Chloride results in decreased activity of ALAD protein]
CTD PMID:14630126 PMID:17624921 PMID:23933410 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
JBrowse link
G Alox5 arachidonate 5-lipoxygenase decreases activity ISO ebselen results in decreased activity of ALOX5 protein CTD PMID:7590103 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP ebselen inhibits the reaction [sodium arsenite results in increased expression of BAX protein] CTD PMID:30558456 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP ebselen inhibits the reaction [sodium arsenite results in decreased expression of BCL2 protein] CTD PMID:30558456 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO
EXP
ebselen inhibits the reaction [Mechlorethamine results in increased activity of CASP3 protein]
ebselen inhibits the reaction [Methylmercury Compounds results in increased activity of CASP3 protein]; ebselen inhibits the reaction [sodium arsenite results in increased expression of CASP3 protein]
ebselen results in increased activity of CASP3 protein
CTD PMID:21300091 PMID:23649643 PMID:25068500 PMID:30558456 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 multiple interactions ISO
EXP
ebselen inhibits the reaction [Mechlorethamine results in increased activity of CASP9 protein]
ebselen inhibits the reaction [Cadmium Chloride results in increased activity of CASP9 protein]
CTD PMID:18629305 PMID:23649643 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase increases activity
multiple interactions
EXP ebselen results in increased activity of CAT protein
ebselen inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]
CTD PMID:27282967 PMID:30558456 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 increases expression ISO ebselen results in increased expression of COX4I1 protein CTD PMID:27385396 NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
JBrowse link
G Cs citrate synthase multiple interactions ISO
EXP
ebselen inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein]
ebselen inhibits the reaction [Cisplatin results in decreased activity of CS protein]
CTD PMID:27385396 PMID:32860823 NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP ebselen inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 mRNA] CTD PMID:11903743 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation EXP ebselen results in increased phosphorylation of EIF2S1 protein CTD PMID:27282967 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Ephx2 epoxide hydrolase 2 multiple interactions ISO ebselen binds to and results in decreased activity of EPHX2 protein CTD PMID:23219563 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 multiple interactions ISO ebselen inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein] CTD PMID:27385396 NCBI chr  X:147,240,239...147,278,057 JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO ebselen inhibits the reaction [Lipopolysaccharides affects the localization of and affects the activity of FOS protein]; ebselen inhibits the reaction [Peroxynitrous Acid affects the localization of and affects the activity of FOS protein] CTD PMID:14572605 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions EXP ebselen inhibits the reaction [Cisplatin results in increased activity of G6PC1 protein] CTD PMID:32860823 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
JBrowse link
G Gck glucokinase multiple interactions ISO [ebselen co-treated with Glucose] results in increased activity of GCK protein CTD PMID:23795780 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
JBrowse link
G Gfap glial fibrillary acidic protein increases phosphorylation EXP ebselen results in increased phosphorylation of GFAP protein CTD PMID:27282967 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions EXP ebselen inhibits the reaction [Oxygen deficiency results in increased expression of GJA1 mRNA]; ebselen inhibits the reaction [Oxygen deficiency results in increased expression of GJA1 protein] CTD PMID:12958040 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO ebselen inhibits the reaction [GPX1 gene mutant form inhibits the reaction [Glucose results in increased secretion of INS1 protein]]
ebselen inhibits the reaction [Methylmercury Compounds results in decreased activity of GPX1 protein]
CTD PMID:23795780 PMID:28383113 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gsr glutathione-disulfide reductase increases activity
multiple interactions
EXP ebselen results in increased activity of GSR protein
ebselen inhibits the reaction [sodium arsenite results in decreased activity of GSR protein]
CTD PMID:27282967 PMID:30558456 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions EXP ebselen binds to and results in decreased activity of [GSTA1 protein binds to GSTA3 protein] CTD PMID:8147899 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 multiple interactions EXP ebselen binds to and results in decreased activity of [GSTA1 protein binds to GSTA3 protein]; ebselen binds to and results in decreased activity of GSTA3 protein CTD PMID:8147899 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions EXP ebselen binds to and results in decreased activity of [GSTM1 protein binds to GSTM2 protein] CTD PMID:8147899 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstm2 glutathione S-transferase mu 2 multiple interactions EXP ebselen binds to and results in decreased activity of [GSTM1 protein binds to GSTM2 protein] CTD PMID:8147899 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions EXP ebselen binds to and results in decreased activity of GSTP1 protein CTD PMID:8147899 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions ISO ebselen inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]; ebselen inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]]; ebselen inhibits the reaction [glutathione glycylethyl ester inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]; ebselen inhibits the reaction [glutathione glycylethyl ester inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]] CTD PMID:19374849 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP [ebselen affects the abundance of Reactive Oxygen Species] which results in decreased expression of HMOX1 protein; [ebselen affects the abundance of Reactive Oxygen Species] which results in increased activity of HMOX1 protein CTD PMID:16959961 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hpgds hematopoietic prostaglandin D synthase increases expression ISO ebselen results in increased expression of HPGDS mRNA CTD PMID:21669866 NCBI chr 4:94,368,426...94,397,931
Ensembl chr 4:94,373,342...94,397,883
JBrowse link
G Hsf1 heat shock transcription factor 1 increases activity ISO ebselen results in increased activity of HSF1 protein CTD PMID:34170685 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Ifng interferon gamma multiple interactions ISO ebselen inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; ebselen inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 protein] CTD PMID:12794164 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il6 interleukin 6 multiple interactions EXP ebselen inhibits the reaction [sodium arsenite results in increased expression of IL6 protein] CTD PMID:30558456 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins1 insulin 1 multiple interactions ISO ebselen inhibits the reaction [GPX1 gene mutant form inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; ebselen inhibits the reaction [SOD1 gene mutant form inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; ebselen promotes the reaction [Glucose results in increased secretion of INS1 protein] CTD PMID:23795780 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
increases activity
ISO
EXP
ebselen inhibits the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]
ebselen analog results in increased phosphorylation of MAPK1 protein; ebselen results in increased phosphorylation of MAPK1 protein
ebselen inhibits the reaction [Methylmercury Compounds results in increased phosphorylation of MAPK1 protein]; ebselen inhibits the reaction [SOD2 protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; ebselen inhibits the reaction [tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex results in increased phosphorylation of and results in increased activity of MAPK1 protein]
ebselen results in increased activity of MAPK1 protein
CTD PMID:20495008 PMID:21300091 PMID:21960664 PMID:22001386 PMID:27282967 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
increases activity
ISO
EXP
ebselen inhibits the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]
ebselen inhibits the reaction [Methylmercury Compounds results in increased phosphorylation of MAPK3 protein]; ebselen inhibits the reaction [SOD2 protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]; ebselen inhibits the reaction [tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex results in increased phosphorylation of and results in increased activity of MAPK3 protein]
ebselen analog results in increased phosphorylation of MAPK3 protein; ebselen results in increased phosphorylation of MAPK3 protein
ebselen results in increased activity of MAPK3 protein
CTD PMID:20495008 PMID:21300091 PMID:21960664 PMID:22001386 PMID:27282967 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation EXP ebselen results in increased phosphorylation of MAPK9 protein CTD PMID:27282967 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions EXP ebselen inhibits the reaction [Carbon Tetrachloride results in decreased expression of MMP13 mRNA] CTD PMID:11903743 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
JBrowse link
G Ngf nerve growth factor multiple interactions ISO ebselen inhibits the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; ebselen inhibits the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:20495008 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases activity
ISO
EXP
ebselen inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; ebselen inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 protein]
ebselen results in decreased activity of NOS2 protein
CTD PMID:7590103 PMID:12794164 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases activity EXP ebselen results in decreased activity of NQO1 protein CTD PMID:7590103 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 multiple interactions ISO [ebselen co-treated with Glucose] results in increased expression of PDX1 protein CTD PMID:23795780 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064
JBrowse link
G Phospho1 phosphoethanolamine/phosphocholine phosphatase 1 decreases activity ISO ebselen results in decreased activity of PHOSPHO1 protein CTD PMID:17227223 NCBI chr10:80,762,062...80,769,596
Ensembl chr10:80,760,792...80,770,342
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO ebselen inhibits the reaction [Lipopolysaccharides affects the localization of and affects the activity of RELA protein]; ebselen inhibits the reaction [Peroxynitrous Acid affects the localization of and affects the activity of RELA protein] CTD PMID:14572605 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Slc11a2 solute carrier family 11 member 2 multiple interactions ISO ebselen inhibits the reaction [SLC11A2 protein results in increased uptake of Iron] CTD PMID:16984886 NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145
JBrowse link
G Slc2a2 solute carrier family 2 member 2 multiple interactions ISO
EXP
[ebselen co-treated with Glucose] results in increased expression of SLC2A2 protein
ebselen inhibits the reaction [Cisplatin results in increased expression of SLC2A2 protein]
CTD PMID:23795780 PMID:32860823 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
JBrowse link
G Smad3 SMAD family member 3 multiple interactions ISO ebselen inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] CTD PMID:21131394 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Sod1 superoxide dismutase 1 decreases response to substance
multiple interactions
ISO ebselen results in decreased susceptibility to SOD1 protein mutant form
ebselen inhibits the reaction [SOD1 gene mutant form inhibits the reaction [Glucose results in increased secretion of INS1 protein]]
CTD PMID:16702190 PMID:23795780 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP ebselen inhibits the reaction [SOD2 protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; ebselen inhibits the reaction [SOD2 protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:20495008 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Tat tyrosine aminotransferase multiple interactions EXP ebselen inhibits the reaction [Cisplatin results in increased activity of TAT protein] CTD PMID:32860823 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP
ISO
ebselen inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA]
ebselen inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; ebselen inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]
CTD PMID:11903743 PMID:16757516 PMID:21131394 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions EXP ebselen inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA] CTD PMID:11903743 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP ebselen inhibits the reaction [sodium arsenite results in increased expression of TNF protein] CTD PMID:30558456 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions ISO ebselen results in increased expression of and results in increased activity of TXNRD1 protein CTD PMID:28383113 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions ISO [ebselen co-treated with Glucose] results in decreased expression of UCP2 protein CTD PMID:23795780 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
G Xbp1 X-box binding protein 1 increases phosphorylation EXP ebselen results in increased phosphorylation of XBP1 protein CTD PMID:27282967 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
G Xpa XPA, DNA damage recognition and repair factor multiple interactions ISO ebselen inhibits the reaction [Zinc binds to XPA protein] CTD PMID:15265038 NCBI chr 5:60,431,673...60,475,726
Ensembl chr 5:60,431,673...60,475,726
JBrowse link
herbacetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fasn fatty acid synthase multiple interactions ISO herbacetin inhibits the reaction [Dietary Fats results in increased activity of FASN protein] CTD PMID:29653099 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions ISO herbacetin inhibits the reaction [Dietary Fats results in increased activity of G6PD protein] CTD PMID:29653099 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO herbacetin inhibits the reaction [Dietary Fats results in increased activity of GPT protein] CTD PMID:29653099 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO herbacetin inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:29653099 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 multiple interactions ISO herbacetin inhibits the reaction [Dietary Fats results in increased expression of SREBF2 mRNA] CTD PMID:29653099 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
JBrowse link
menadione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin affects expression ISO Vitamin K 3 affects the expression of A2M mRNA CTD PMID:20044591 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 decreases expression ISO Vitamin K 3 results in decreased expression of ABCB11 mRNA CTD PMID:34767876 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb7 ATP binding cassette subfamily B member 7 affects expression ISO Vitamin K 3 affects the expression of ABCB7 mRNA CTD PMID:20044591 NCBI chr  X:69,295,598...69,436,775
Ensembl chr  X:69,295,552...69,436,858
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 affects expression ISO Vitamin K 3 affects the expression of ABCC3 mRNA CTD PMID:20044591 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcd4 ATP binding cassette subfamily D member 4 decreases expression ISO Vitamin K 3 results in decreased expression of ABCD4 mRNA CTD PMID:25270620 NCBI chr 6:104,246,459...104,260,965
Ensembl chr 6:104,246,468...104,280,276
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 affects expression ISO Vitamin K 3 affects the expression of ABCG2 mRNA CTD PMID:20044591 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Abhd14b abhydrolase domain containing 14b affects expression ISO Vitamin K 3 affects the expression of ABHD14B mRNA CTD PMID:20044591 NCBI chr 8:107,087,157...107,092,122
Ensembl chr 8:107,088,069...107,092,119
JBrowse link
G Abhd4 abhydrolase domain containing 4, N-acyl phospholipase B increases expression ISO Vitamin K 3 results in increased expression of ABHD4 mRNA CTD PMID:25270620 NCBI chr15:27,697,384...27,716,013
Ensembl chr15:27,704,113...27,716,966
JBrowse link
G Abhd5 abhydrolase domain containing 5, lysophosphatidic acid acyltransferase affects expression ISO Vitamin K 3 affects the expression of ABHD5 mRNA CTD PMID:20044591 NCBI chr 8:122,000,241...122,026,447
Ensembl chr 8:122,000,389...122,026,447
JBrowse link
G Abr ABR activator of RhoGEF and GTPase affects expression ISO Vitamin K 3 affects the expression of ABR mRNA CTD PMID:20044591 NCBI chr10:61,262,516...61,461,331
Ensembl chr10:61,262,516...61,461,505
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 affects expression ISO Vitamin K 3 affects the expression of ACAT2 mRNA CTD PMID:20044591 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
JBrowse link
G Aco1 aconitase 1 affects activity ISO Vitamin K 3 affects the activity of ACO1 protein CTD PMID:10037708 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
JBrowse link
G Aco2 aconitase 2 affects expression ISO Vitamin K 3 affects the expression of ACO2 mRNA CTD PMID:20044591 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Acot13 acyl-CoA thioesterase 13 affects expression ISO Vitamin K 3 affects the expression of ACOT13 mRNA CTD PMID:20044591 NCBI chr17:40,240,378...40,252,851
Ensembl chr17:40,240,378...40,252,851
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 affects expression ISO Vitamin K 3 affects the expression of ACSL1 mRNA CTD PMID:20044591 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Acss1 acyl-CoA synthetase short-chain family member 1 affects expression ISO Vitamin K 3 affects the expression of ACSS1 mRNA CTD PMID:20044591 NCBI chr 3:139,450,383...139,500,325
Ensembl chr 3:139,450,383...139,500,325
JBrowse link
G Actr3b actin related protein 3B affects expression ISO Vitamin K 3 affects the expression of ACTR3B mRNA CTD PMID:20044591 NCBI chr 4:9,261,631...9,355,496
Ensembl chr 4:9,262,233...9,355,441
JBrowse link
G Adam19 ADAM metallopeptidase domain 19 decreases expression ISO Vitamin K 3 results in decreased expression of ADAM19 mRNA CTD PMID:25270620 NCBI chr10:30,491,362...30,583,115
Ensembl chr10:30,491,405...30,583,105
JBrowse link
G Adam9 ADAM metallopeptidase domain 9 affects expression ISO Vitamin K 3 affects the expression of ADAM9 mRNA CTD PMID:23410634 NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917
JBrowse link
G Adcy3 adenylate cyclase 3 affects expression
decreases expression
ISO Vitamin K 3 affects the expression of ADCY3 mRNA
Vitamin K 3 results in decreased expression of ADCY3 mRNA
CTD PMID:12414654 PMID:20044591 NCBI chr 6:27,100,089...27,203,686
Ensembl chr 6:27,124,828...27,203,686
JBrowse link
G Add3 adducin 3 affects expression ISO Vitamin K 3 affects the expression of ADD3 mRNA CTD PMID:20044591 NCBI chr 1:252,147,341...252,255,126
Ensembl chr 1:252,147,386...252,255,124
JBrowse link
G Adgra3 adhesion G protein-coupled receptor A3 affects expression ISO Vitamin K 3 affects the expression of ADGRA3 mRNA CTD PMID:20044591 NCBI chr14:60,874,719...60,976,341
Ensembl chr14:60,874,715...60,976,332
JBrowse link
G Adgrv1 adhesion G protein-coupled receptor V1 affects expression ISO Vitamin K 3 affects the expression of ADGRV1 mRNA CTD PMID:20044591 NCBI chr 2:11,331,434...11,911,713
Ensembl chr 2:11,331,442...11,911,688
JBrowse link
G Adk adenosine kinase affects expression ISO Vitamin K 3 affects the expression of ADK mRNA CTD PMID:20044591 NCBI chr15:2,863,241...3,246,453
Ensembl chr15:2,863,244...3,246,510
JBrowse link
G Ago1 argonaute RISC component 1 affects expression ISO Vitamin K 3 affects the expression of AGO1 mRNA CTD PMID:20044591 NCBI chr 5:138,722,111...138,757,118
Ensembl chr 5:138,722,111...138,773,546
JBrowse link
G Agpat3 1-acylglycerol-3-phosphate O-acyltransferase 3 affects expression ISO Vitamin K 3 affects the expression of AGPAT3 mRNA CTD PMID:20044591 NCBI chr20:10,330,960...10,415,358
Ensembl chr20:10,384,507...10,415,358
JBrowse link
G Agr2 anterior gradient 2, protein disulphide isomerase family member affects expression ISO Vitamin K 3 affects the expression of AGR2 mRNA CTD PMID:20044591 NCBI chr 6:52,708,602...52,729,378
Ensembl chr 6:52,708,602...52,729,371
JBrowse link
G Ahr aryl hydrocarbon receptor affects expression ISO Vitamin K 3 affects the expression of AHR mRNA CTD PMID:20044591 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Aire autoimmune regulator decreases expression ISO Vitamin K 3 results in decreased expression of AIRE mRNA CTD PMID:25270620 NCBI chr20:10,636,058...10,651,060
Ensembl chr20:10,636,123...10,651,060
JBrowse link
G Akap12 A-kinase anchoring protein 12 affects expression ISO Vitamin K 3 affects the expression of AKAP12 mRNA CTD PMID:23410634 NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886
JBrowse link
G Akap9 A-kinase anchoring protein 9 affects expression ISO Vitamin K 3 affects the expression of AKAP9 mRNA CTD PMID:20044591 NCBI chr 4:30,056,738...30,192,716
Ensembl chr 4:30,056,738...30,192,606
JBrowse link
G Akip1 A-kinase interacting protein 1 affects expression ISO Vitamin K 3 affects the expression of AKIP1 mRNA CTD PMID:20044591 NCBI chr 1:163,734,730...163,743,648
Ensembl chr 1:163,734,798...163,743,648
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO Vitamin K 3 results in increased expression of AKR1B10 mRNA CTD PMID:23410634 PMID:34767876 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 affects expression ISO Vitamin K 3 affects the expression of AKR1C1 mRNA CTD PMID:20044591 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO Vitamin K 3 results in increased expression of AKR1C2 mRNA CTD PMID:12414654 PMID:23410634 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 multiple interactions
increases metabolic processing
decreases response to substance
ISO AKR7A2 protein inhibits the reaction [Vitamin K 3 results in decreased abundance of Glutathione]; AKR7A2 protein inhibits the reaction [Vitamin K 3 results in increased abundance of Reactive Oxygen Species]
AKR7A5 protein results in increased metabolism of Vitamin K 3
AKR7A2 protein results in decreased susceptibility to Vitamin K 3
CTD PMID:22001351 PMID:24590062 NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909
JBrowse link
G Alb albumin affects expression ISO Vitamin K 3 affects the expression of ALB mRNA CTD PMID:20044591 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 affects expression ISO Vitamin K 3 affects the expression of ALDH18A1 mRNA CTD PMID:20044591 NCBI chr 1:239,375,657...239,407,956
Ensembl chr 1:239,375,669...239,407,890
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 affects expression ISO Vitamin K 3 affects the expression of ALDH1A1 mRNA CTD PMID:23410634 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 affects expression ISO Vitamin K 3 affects the expression of ALDH1A3 mRNA CTD PMID:20829426 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member affects expression ISO Vitamin K 3 affects the expression of ALDH2 mRNA CTD PMID:20044591 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Aldh3b1 aldehyde dehydrogenase 3 family, member B1 decreases response to substance ISO ALDH3B1 protein results in decreased susceptibility to Vitamin K 3 CTD PMID:20699116 NCBI chr 1:201,145,309...201,162,675
Ensembl chr 1:201,145,309...201,163,921
JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 affects expression ISO Vitamin K 3 affects the expression of ALDH6A1 mRNA CTD PMID:20044591 NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated decreases secretion ISO Vitamin K 3 results in decreased secretion of ALPL protein CTD PMID:30453296 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
JBrowse link
G Alyref Aly/REF export factor affects expression ISO Vitamin K 3 affects the expression of ALYREF mRNA CTD PMID:20044591 NCBI chr10:105,871,424...105,875,076
Ensembl chr10:105,871,306...105,875,069
JBrowse link
G Amotl2 angiomotin like 2 affects expression ISO Vitamin K 3 affects the expression of AMOTL2 mRNA CTD PMID:20044591 NCBI chr 8:103,303,368...103,319,161
Ensembl chr 8:103,302,992...103,318,910
JBrowse link
G Anapc1 anaphase promoting complex subunit 1 affects expression ISO Vitamin K 3 affects the expression of ANAPC1 mRNA CTD PMID:20044591 NCBI chr 3:115,850,117...115,930,259
Ensembl chr 3:115,850,185...115,930,273
JBrowse link
G Ang angiogenin affects expression ISO Vitamin K 3 affects the expression of ANG mRNA CTD PMID:20044591 NCBI chr15:24,312,711...24,323,361 JBrowse link
G Ank3 ankyrin 3 affects expression ISO Vitamin K 3 affects the expression of ANK3 mRNA CTD PMID:20044591 NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300
JBrowse link
G Ankra2 ankyrin repeat family A member 2 affects expression ISO Vitamin K 3 affects the expression of ANKRA2 mRNA CTD PMID:23410634 NCBI chr 2:29,612,867...29,623,748
Ensembl chr 2:29,612,925...29,623,730
JBrowse link
G Ankrd11 ankyrin repeat domain containing 11 affects expression ISO Vitamin K 3 affects the expression of ANKRD11 mRNA CTD PMID:20044591 NCBI chr19:50,940,284...51,098,962
Ensembl chr19:50,940,299...51,098,962
JBrowse link
G Ankrd37 ankyrin repeat domain 37 decreases expression ISO Vitamin K 3 results in decreased expression of ANKRD37 mRNA CTD PMID:25270620 NCBI chr16:46,268,933...46,271,971
Ensembl chr16:46,268,443...46,271,963
JBrowse link
G Anks1a ankyrin repeat and sterile alpha motif domain containing 1A affects expression ISO Vitamin K 3 affects the expression of ANKS1 mRNA CTD PMID:20044591 NCBI chr20:5,963,658...6,117,139
Ensembl chr20:5,963,678...6,117,148
JBrowse link
G Anks6 ankyrin repeat and sterile alpha motif domain containing 6 affects expression ISO Vitamin K 3 affects the expression of ANKS6 mRNA CTD PMID:20044591 NCBI chr 5:61,309,183...61,350,596
Ensembl chr 5:61,309,183...61,350,596
JBrowse link
G Anp32b acidic nuclear phosphoprotein 32 family member B affects expression ISO Vitamin K 3 affects the expression of ANP32B mRNA CTD PMID:20044591 NCBI chr 5:60,743,077...60,765,726
Ensembl chr 5:60,743,443...60,765,717
JBrowse link
G Antkmt adenine nucleotide translocase lysine methyltransferase affects expression ISO Vitamin K 3 affects the expression of ANTKMT mRNA CTD PMID:20044591 NCBI chr10:14,812,274...14,814,798
Ensembl chr10:14,812,269...14,814,193
JBrowse link
G Anxa13 annexin A13 affects expression ISO Vitamin K 3 affects the expression of ANXA13 mRNA CTD PMID:20044591 NCBI chr 7:89,884,356...89,936,907
Ensembl chr 7:89,884,356...89,936,907
JBrowse link
G Aox1 aldehyde oxidase 1 multiple interactions
decreases activity
ISO Vitamin K 3 inhibits the reaction [AOX1 protein results in increased metabolism of zoniporide]
Vitamin K 3 results in decreased activity of AOX1 protein
CTD PMID:20040581 NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770
JBrowse link
G Apbb2 amyloid beta precursor protein binding family B member 2 affects expression ISO Vitamin K 3 affects the expression of APBB2 mRNA CTD PMID:20044591 NCBI chr14:41,557,918...41,878,622
Ensembl chr14:41,557,972...41,877,495
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases response to substance ISO APEX1 gene mutant form results in increased susceptibility to Vitamin K 3 CTD PMID:11454706 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
JBrowse link
G Aplp2 amyloid beta precursor like protein 2 affects expression ISO Vitamin K 3 affects the expression of APLP2 mRNA CTD PMID:20044591 NCBI chr 8:29,599,230...29,662,311
Ensembl chr 8:29,599,230...29,661,855
JBrowse link
G Apoa1 apolipoprotein A1 affects expression ISO Vitamin K 3 affects the expression of APOA1 mRNA CTD PMID:20829426 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoa5 apolipoprotein A5 affects expression ISO Vitamin K 3 affects the expression of APOA5 mRNA CTD PMID:23410634 NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816
JBrowse link
G Apoc3 apolipoprotein C3 affects expression ISO Vitamin K 3 affects the expression of APOC3 mRNA CTD PMID:20044591 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Apoe apolipoprotein E affects response to substance ISO APOE protein affects the susceptibility to Vitamin K 3 CTD PMID:28728140 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Apoh apolipoprotein H affects expression ISO Vitamin K 3 affects the expression of APOH mRNA CTD PMID:20044591 NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329
JBrowse link
G Aqp11 aquaporin 11 affects expression ISO Vitamin K 3 affects the expression of AQP11 mRNA CTD PMID:20044591 NCBI chr 1:152,046,515...152,056,675
Ensembl chr 1:152,046,517...152,056,725
JBrowse link
G Areg amphiregulin increases expression ISO Vitamin K 3 results in increased expression of AREG mRNA CTD PMID:12414654 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Arg2 arginase 2 affects expression ISO Vitamin K 3 affects the expression of ARG2 mRNA CTD PMID:23410634 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
JBrowse link
G Arhgef7 Rho guanine nucleotide exchange factor 7 affects expression ISO Vitamin K 3 affects the expression of ARHGEF7 mRNA CTD PMID:20044591 NCBI chr16:77,671,021...77,782,593
Ensembl chr16:77,671,023...77,782,697
JBrowse link
G Arid3a AT-rich interaction domain 3A affects expression ISO Vitamin K 3 affects the expression of ARID3A mRNA CTD PMID:20044591 PMID:23410634 NCBI chr 7:9,755,291...9,781,260
Ensembl chr 7:9,755,294...9,780,599
JBrowse link
G Arid5a AT-rich interaction domain 5A affects expression ISO Vitamin K 3 affects the expression of ARID5A mRNA CTD PMID:20044591 NCBI chr 9:38,534,612...38,549,467
Ensembl chr 9:38,534,590...38,547,597
JBrowse link
G Armcx1 armadillo repeat containing, X-linked 1 decreases expression ISO Vitamin K 3 results in decreased expression of ARMCX1 mRNA CTD PMID:25270620 NCBI chr  X:97,898,969...97,902,874
Ensembl chr  X:97,898,883...97,903,299
JBrowse link
G Arrdc2 arrestin domain containing 2 affects expression ISO Vitamin K 3 affects the expression of ARRDC2 mRNA CTD PMID:20044591 NCBI chr16:18,601,897...18,606,029
Ensembl chr16:18,601,897...18,606,029
JBrowse link
G Asf1a anti-silencing function 1A histone chaperone increases expression ISO Vitamin K 3 results in increased expression of ASF1A mRNA CTD PMID:23410634 NCBI chr20:32,893,962...32,908,808
Ensembl chr20:32,893,573...32,908,808
JBrowse link
G Asic1 acid sensing ion channel subunit 1 decreases expression ISO Vitamin K 3 results in decreased expression of ASIC1 mRNA CTD PMID:25270620 NCBI chr 7:130,798,317...130,828,535
Ensembl chr 7:130,799,917...130,828,541
JBrowse link
G Atf3 activating transcription factor 3 affects expression
increases expression
ISO Vitamin K 3 affects the expression of ATF3 mRNA
Vitamin K 3 results in increased expression of ATF3 mRNA
CTD PMID:12414654 PMID:20044591 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions
increases expression
ISO Metyrapone promotes the reaction [Vitamin K 3 results in increased expression of ATF6 protein]; S 3483 promotes the reaction [Vitamin K 3 results in increased expression of ATF6 protein] CTD PMID:19819344 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Atg5 autophagy related 5 affects response to substance EXP
ISO
ATG5 mRNA affects the susceptibility to Vitamin K 3
ATG5 protein affects the susceptibility to Vitamin K 3
CTD PMID:18073215 PMID:18319638 PMID:20578144 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase affects expression ISO Vitamin K 3 affects the expression of ATIC mRNA CTD PMID:20044591 NCBI chr 9:73,164,846...73,184,897
Ensembl chr 9:73,164,846...73,184,889
JBrowse link
G Atox1 antioxidant 1 copper chaperone affects expression ISO Vitamin K 3 affects the expression of ATOX1 mRNA CTD PMID:20044591 NCBI chr10:39,564,855...39,579,892
Ensembl chr10:39,564,857...39,579,950
JBrowse link
G Atp5if1 ATP synthase inhibitory factor subunit 1 affects expression ISO Vitamin K 3 affects the expression of ATP5IF1 mRNA CTD PMID:20044591 NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668
JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP affects expression ISO Vitamin K 3 affects the expression of ATP5PO mRNA CTD PMID:20044591 NCBI chr11:31,165,218...31,171,530
Ensembl chr11:31,165,217...31,171,592
JBrowse link
G Atp7b ATPase copper transporting beta affects expression ISO Vitamin K 3 affects the expression of ATP7B mRNA CTD PMID:20044591 NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
JBrowse link
G Atrn attractin affects expression ISO Vitamin K 3 affects the expression of ATRN mRNA CTD PMID:20044591 NCBI chr 3:118,110,320...118,244,326
Ensembl chr 3:118,110,229...118,244,322
JBrowse link
G Atrx ATRX, chromatin remodeler affects expression ISO Vitamin K 3 affects the expression of ATRX mRNA CTD PMID:20829426 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330
JBrowse link
G Atxn2l ataxin 2-like affects expression ISO Vitamin K 3 affects the expression of ATXN2L mRNA CTD PMID:20044591 NCBI chr 1:181,078,293...181,090,079
Ensembl chr 1:181,078,288...181,089,686
JBrowse link
G Auh AU RNA binding methylglutaconyl-CoA hydratase affects expression ISO Vitamin K 3 affects the expression of AUH mRNA CTD PMID:20044591 NCBI chr17:12,329,522...12,424,882
Ensembl chr17:12,329,524...12,424,896
JBrowse link
G Aurkb aurora kinase B decreases expression ISO Vitamin K 3 results in decreased expression of AURKB mRNA CTD PMID:12414654 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
JBrowse link
G Auts2 activator of transcription and developmental regulator AUTS2 affects expression ISO Vitamin K 3 affects the expression of AUTS2 mRNA CTD PMID:20044591 NCBI chr12:24,104,187...25,194,123
Ensembl chr12:24,104,192...25,194,416
JBrowse link
G B3galt6 Beta-1,3-galactosyltransferase 6 affects expression ISO Vitamin K 3 affects the expression of B3GALT6 mRNA CTD PMID:20044591 NCBI chr 5:166,584,202...166,586,338
Ensembl chr 5:166,584,202...166,586,338
JBrowse link
G Bahd1 bromo adjacent homology domain containing 1 affects expression ISO Vitamin K 3 affects the expression of BAHD1 mRNA CTD PMID:20044591 NCBI chr 3:105,891,207...105,914,414
Ensembl chr 3:105,892,478...105,914,410
JBrowse link
G Bak1 BCL2-antagonist/killer 1 affects expression ISO Vitamin K 3 affects the expression of BAK1 mRNA CTD PMID:20044591 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor affects expression ISO Vitamin K 3 affects the expression of BAMBI mRNA CTD PMID:23410634 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060
JBrowse link
G Batf basic leucine zipper ATF-like transcription factor increases expression ISO Vitamin K 3 results in increased expression of BATF mRNA CTD PMID:25270620 NCBI chr 6:105,353,715...105,376,051
Ensembl chr 6:105,353,715...105,376,051
JBrowse link
G Bax BCL2 associated X, apoptosis regulator affects localization
increases expression
multiple interactions
EXP
ISO
Vitamin K 3 affects the localization of BAX protein
Vitamin K 3 results in increased expression of BAX protein
EUK-134 inhibits the reaction [Vitamin K 3 results in increased expression of BAX protein]
CTD PMID:15961378 PMID:25005833 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 affects expression ISO Vitamin K 3 affects the expression of BBC3 mRNA CTD PMID:20044591 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bbs2 Bardet-Biedl syndrome 2 affects expression ISO Vitamin K 3 affects the expression of BBS2 mRNA CTD PMID:20044591 NCBI chr19:10,909,653...10,944,998
Ensembl chr19:10,909,619...10,944,993
JBrowse link
G Bcar3 BCAR3 adaptor protein, NSP family member affects expression ISO Vitamin K 3 affects the expression of BCAR3 mRNA CTD PMID:20044591 NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798
JBrowse link
G Bcas1 brain enriched myelin associated protein 1 affects expression ISO Vitamin K 3 affects the expression of BCAS1 mRNA CTD PMID:20044591 NCBI chr 3:159,136,077...159,219,072
Ensembl chr 3:159,136,083...159,219,106
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
ISO
EXP
[sodium arsenite co-treated with Vitamin K 3] results in decreased expression of BCL2 protein; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in decreased expression of BCL2 protein]; EUK-134 inhibits the reaction [Vitamin K 3 results in decreased expression of BCL2 protein]
Vitamin K 3 results in decreased expression of BCL2 mRNA; Vitamin K 3 results in decreased expression of BCL2 protein
Acetaminophen inhibits the reaction [Vitamin K 3 results in decreased expression of BCL2 mRNA]; Acetaminophen inhibits the reaction [Vitamin K 3 results in decreased expression of BCL2 protein]
CTD PMID:19082730 PMID:19265712 PMID:25005833 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl6 BCL6, transcription repressor affects expression ISO Vitamin K 3 affects the expression of BCL6 mRNA CTD PMID:20044591 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
JBrowse link
G Bcl9l BCL9 like decreases expression ISO Vitamin K 3 results in decreased expression of BCL9L protein CTD PMID:31238027 NCBI chr 8:44,811,977...44,840,611
Ensembl chr 8:44,811,977...44,840,611
JBrowse link
G Bdh2 3-hydroxybutyrate dehydrogenase 2 affects expression ISO Vitamin K 3 affects the expression of BDH2 mRNA CTD PMID:20044591 NCBI chr 2:223,702,410...223,723,076
Ensembl chr 2:223,702,412...223,723,072
JBrowse link
G Becn1 beclin 1 affects expression ISO Vitamin K 3 affects the expression of BECN1 mRNA CTD PMID:20044591 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bet1l Bet1 golgi vesicular membrane trafficking protein-like affects expression ISO Vitamin K 3 affects the expression of BET1L mRNA CTD PMID:20044591 NCBI chr 1:195,931,407...195,935,072
Ensembl chr 1:195,931,411...195,935,040
JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases expression
increases secretion
increases expression
multiple interactions
ISO Vitamin K 3 results in decreased expression of BGLAP mRNA
Vitamin K 3 results in increased secretion of BGLAP protein
Vitamin K 3 results in increased expression of BGLAP protein modified form
Vitamin K 3 inhibits the reaction [Estrogens deficiency results in decreased secretion of BGLAP protein]
CTD PMID:19675304 PMID:30453296 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Bik BCL2-interacting killer increases expression ISO Vitamin K 3 results in increased expression of BIK mRNA CTD PMID:23410634 NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 affects expression ISO Vitamin K 3 affects the expression of BIRC5 mRNA CTD PMID:20044591 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Blvrb biliverdin reductase B increases expression ISO Vitamin K 3 results in increased expression of BLVRB mRNA CTD PMID:25270620 NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375
JBrowse link
G Bms1 BMS1 ribosome biogenesis factor affects expression ISO Vitamin K 3 affects the expression of BMS1 mRNA CTD PMID:20044591 NCBI chr 4:151,558,163...151,595,187
Ensembl chr 4:151,558,163...151,595,127
JBrowse link
G Bnip3 BCL2 interacting protein 3 decreases expression ISO Vitamin K 3 results in decreased expression of BNIP3 mRNA CTD PMID:25270620 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Brd8 bromodomain containing 8 affects expression ISO Vitamin K 3 affects the expression of BRD8 mRNA CTD PMID:20044591 NCBI chr18:26,204,892...26,229,999
Ensembl chr18:26,181,732...26,229,884
JBrowse link
G Brms1 BRMS1, transcriptional repressor and anoikis regulator affects expression ISO Vitamin K 3 affects the expression of BRMS1 mRNA CTD PMID:20044591 NCBI chr 1:202,345,766...202,355,028
Ensembl chr 1:202,345,704...202,355,028
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Vitamin K 3 results in increased expression of BTG2 mRNA CTD PMID:12414654 PMID:21382384 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase affects expression ISO Vitamin K 3 affects the expression of BUB1 mRNA CTD PMID:20044591 PMID:23410634 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
JBrowse link
G Bud13 BUD13 homolog affects expression ISO Vitamin K 3 affects the expression of BUD13 mRNA CTD PMID:20044591 NCBI chr 8:46,575,124...46,590,964
Ensembl chr 8:46,575,115...46,590,958
JBrowse link
G C10h17orf100 similar to human chromosome 17 open reading frame 100 affects expression ISO Vitamin K 3 affects the expression of C17ORF100 mRNA CTD PMID:23410634 NCBI chr10:56,840,451...56,843,674
Ensembl chr10:56,832,412...56,843,871
JBrowse link
G C11h3orf52 similar to human chromosome 3 open reading frame 52 affects expression ISO Vitamin K 3 affects the expression of C3ORF52 mRNA CTD PMID:20044591 NCBI chr11:55,166,986...55,192,273
Ensembl chr11:55,166,678...55,192,292
JBrowse link
G C17h6orf62 similar to human chromosome 6 open reading frame 62 affects expression ISO Vitamin K 3 affects the expression of C6ORF62 mRNA CTD PMID:23410634 NCBI chr17:40,256,211...40,267,851
Ensembl chr17:40,256,211...40,276,020
JBrowse link
G C1galt1c1 C1GALT1-specific chaperone 1 affects expression ISO Vitamin K 3 affects the expression of C1GALT1C1 mRNA CTD PMID:20044591 NCBI chr  X:117,378,123...117,382,620
Ensembl chr  X:117,375,525...117,382,787
JBrowse link
G C1qbp complement C1q binding protein affects expression ISO Vitamin K 3 affects the expression of C1QBP mRNA CTD PMID:20044591 NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649
JBrowse link
G C2cd5 C2 calcium-dependent domain containing 5 affects expression ISO Vitamin K 3 affects the expression of C2CD5 mRNA CTD PMID:20044591 NCBI chr 4:175,969,544...176,055,597
Ensembl chr 4:175,969,545...176,055,558
JBrowse link
G C7h8orf76 similar to human chromosome 8 open reading frame 76 affects expression ISO Vitamin K 3 affects the expression of C8ORF76 mRNA CTD PMID:23410634 NCBI chr 7:89,558,890...89,569,810
Ensembl chr 7:89,558,909...89,569,810
JBrowse link
G C8h15orf39 similar to human chromosome 15 open reading frame 39 affects expression ISO Vitamin K 3 affects the expression of C15ORF39 mRNA CTD PMID:20044591 NCBI chr 8:57,646,324...57,655,896
Ensembl chr 8:57,645,756...57,655,941
JBrowse link
G Cables1 Cdk5 and Abl enzyme substrate 1 affects expression ISO Vitamin K 3 affects the expression of CABLES1 mRNA CTD PMID:20044591 NCBI chr18:3,076,556...3,181,181
Ensembl chr18:3,075,524...3,181,181
JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G affects expression ISO Vitamin K 3 affects the expression of CACNA1G mRNA CTD PMID:20044591 NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752
JBrowse link
G Calb1 calbindin 1 increases expression ISO Vitamin K 3 results in increased expression of CALB1 mRNA CTD PMID:30453296 NCBI chr 5:29,375,624...29,402,532
Ensembl chr 5:29,375,642...29,402,431
JBrowse link
G Camk2n1 calcium/calmodulin-dependent protein kinase II inhibitor 1 affects expression ISO Vitamin K 3 affects the expression of CAMK2N1 mRNA CTD PMID:20044591 NCBI chr 5:150,674,819...150,676,600
Ensembl chr 5:150,673,507...150,676,600
JBrowse link
G Canx calnexin affects expression ISO Vitamin K 3 affects the expression of CANX mRNA CTD PMID:20044591 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
JBrowse link
G Capn2 calpain 2 affects expression ISO Vitamin K 3 affects the expression of CAPN2 mRNA CTD PMID:23410634 NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969
JBrowse link
G Car12 carbonic anhydrase 12 affects expression ISO Vitamin K 3 affects the expression of CA12 mRNA CTD PMID:20044591 NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440
JBrowse link
G Casp2 caspase 2 increases expression ISO Vitamin K 3 results in increased expression of CASP2 protein modified form CTD PMID:20829426 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases cleavage
increases expression
ISO
EXP
[sodium arsenite co-treated with Vitamin K 3] results in increased activity of CASP3 protein; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in increased activity of CASP3 protein]; Vitamin K 3 analog inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; Vitamin K 3 analog promotes the reaction [Doxorubicin results in increased activity of CASP3 protein]
Vitamin K 3 results in increased activity of CASP3 protein
Vitamin K 3 results in increased cleavage of CASP3 protein
Buthionine Sulfoximine promotes the reaction [Vitamin K 3 results in increased activity of CASP3 protein]; pyrazolanthrone inhibits the reaction [Vitamin K 3 results in increased cleavage of CASP3 protein]; U 0126 promotes the reaction [Vitamin K 3 results in increased activity of CASP3 protein]
Vitamin K 3 results in increased expression of CASP3 protein modified form
CTD PMID:12965111 PMID:16310883 PMID:19082730 PMID:20829426 PMID:23300732 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 multiple interactions ISO [Metyrapone co-treated with Vitamin K 3] affects the localization of CASP4 protein; [S 3483 co-treated with Vitamin K 3] affects the localization of CASP4 protein CTD PMID:19819344 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp6 caspase 6 multiple interactions
increases cleavage
EXP pyrazolanthrone inhibits the reaction [Vitamin K 3 results in increased activity of CASP6 protein]; pyrazolanthrone inhibits the reaction [Vitamin K 3 results in increased cleavage of CASP6 protein] CTD PMID:16310883 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage
ISO
EXP
[sodium arsenite co-treated with Vitamin K 3] results in increased activity of CASP9 protein; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in increased activity of CASP9 protein]; EUK-134 inhibits the reaction [Vitamin K 3 results in increased cleavage of CASP9 protein]; Vitamin K 3 analog promotes the reaction [Doxorubicin results in increased activity of CASP9 protein]
pyrazolanthrone inhibits the reaction [Vitamin K 3 results in increased cleavage of CASP9 protein]
CTD PMID:16310883 PMID:19082730 PMID:25005833 PMID:29141199 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase affects expression
decreases activity
decreases response to substance
multiple interactions
ISO
EXP
Vitamin K 3 affects the expression of CAT mRNA
Vitamin K 3 results in decreased activity of CAT protein
CAT protein results in decreased susceptibility to Vitamin K 3
[CAT protein co-treated with SOD1 protein] results in decreased susceptibility to Vitamin K 3; [CAT protein co-treated with SOD2 protein] results in decreased susceptibility to Vitamin K 3; CAT protein inhibits the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; CAT protein inhibits the reaction [[DCXR protein results in increased metabolism of Vitamin K 3] which results in increased chemical synthesis of Hydrogen Peroxide]; CAT results in decreased susceptibility to [Vitamin K 3 co-treated with Ascorbic Acid]
CTD PMID:12633745 PMID:14698046 PMID:15331536 PMID:20044591 PMID:21689642 More... NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cavin2 caveolae associated protein 2 affects expression ISO Vitamin K 3 affects the expression of CAVIN2 mRNA CTD PMID:23410634 NCBI chr 9:50,302,079...50,314,096
Ensembl chr 9:50,301,206...50,314,147
JBrowse link
G Cbfb core-binding factor subunit beta affects expression ISO Vitamin K 3 affects the expression of CBFB mRNA CTD PMID:20044591 NCBI chr19:33,049,162...33,092,752
Ensembl chr19:33,049,172...33,092,751
JBrowse link
G Cbr1 carbonyl reductase 1 multiple interactions
increases metabolic processing
ISO [S-Nitrosoglutathione binds to CBR1 protein] inhibits the reaction [CBR1 protein results in increased metabolism of Vitamin K 3]; Vitamin K 3 inhibits the reaction [CBR1 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] CTD PMID:11306090 PMID:19061875 PMID:23295225 NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393
JBrowse link
G Cbr3 carbonyl reductase 3 affects metabolic processing
increases expression
ISO CBR3 protein affects the metabolism of Vitamin K 3
Vitamin K 3 results in increased expression of CBR3 mRNA
CTD PMID:20007405 PMID:21382384 PMID:25270620 NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875
JBrowse link
G Ccar2 cell cycle and apoptosis regulator 2 affects expression ISO Vitamin K 3 affects the expression of CCAR2 mRNA CTD PMID:20044591 NCBI chr15:45,212,797...45,228,001
Ensembl chr15:45,212,803...45,227,636
JBrowse link
G Ccdc12 coiled-coil domain containing 12 affects expression ISO Vitamin K 3 affects the expression of CCDC12 mRNA CTD PMID:20044591 NCBI chr 8:110,635,276...110,686,417
Ensembl chr 8:110,635,710...110,686,417
JBrowse link
G Ccdc125 coiled-coil domain containing 125 affects expression ISO Vitamin K 3 affects the expression of CCDC125 mRNA CTD PMID:20044591 NCBI chr 2:31,809,120...31,835,538
Ensembl chr 2:31,809,228...31,850,152
JBrowse link
G Ccdc136 coiled-coil domain containing 136 decreases expression ISO Vitamin K 3 results in decreased expression of CCDC136 mRNA CTD PMID:25270620 NCBI chr 4:57,997,825...58,027,598
Ensembl chr 4:57,997,853...58,027,646
JBrowse link
G Ccdc88b coiled-coil domain containing 88B affects expression ISO Vitamin K 3 affects the expression of CCDC88B mRNA CTD PMID:20044591 NCBI chr 1:204,036,913...204,052,878
Ensembl chr 1:204,036,918...204,052,970
JBrowse link
G Ccdc90b coiled-coil domain containing 90B affects expression ISO Vitamin K 3 affects the expression of CCDC90B mRNA CTD PMID:20044591 NCBI chr 1:146,632,756...146,646,314
Ensembl chr 1:146,633,036...146,647,338
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions
increases secretion
increases expression
EXP Acetaminophen inhibits the reaction [Vitamin K 3 results in increased expression of CCL3 mRNA]; Acetaminophen inhibits the reaction [Vitamin K 3 results in increased secretion of CCL3 protein] CTD PMID:19265712 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions
increases secretion
increases expression
EXP Acetaminophen inhibits the reaction [Vitamin K 3 results in increased expression of CCL5 mRNA]; Acetaminophen inhibits the reaction [Vitamin K 3 results in increased secretion of CCL5 protein] CTD PMID:19265712 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccn1 cellular communication network factor 1 increases expression ISO Vitamin K 3 results in increased expression of CCN1 mRNA CTD PMID:12414654 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Ccn2 cellular communication network factor 2 affects expression ISO Vitamin K 3 affects the expression of CCN2 mRNA CTD PMID:20044591 PMID:23410634 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccna2 cyclin A2 decreases expression
affects expression
ISO Vitamin K 3 results in decreased expression of CCNA2 mRNA
Vitamin K 3 affects the expression of CCNA2 mRNA
CTD PMID:12414654 PMID:23410634 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb2 cyclin B2 affects expression ISO Vitamin K 3 affects the expression of CCNB2 mRNA CTD PMID:20044591 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccnd1 cyclin D1 affects expression
decreases expression
ISO Vitamin K 3 affects the expression of CCND1 mRNA
Vitamin K 3 results in decreased expression of CCND1 protein
CTD PMID:20044591 PMID:31238027 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccne1 cyclin E1 affects expression ISO Vitamin K 3 affects the expression of CCNE1 mRNA CTD PMID:20044591 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Ccng1 cyclin G1 affects expression ISO Vitamin K 3 affects the expression of CCNG1 mRNA CTD PMID:20044591 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Ccni cyclin I affects expression ISO Vitamin K 3 affects the expression of CCNI mRNA CTD PMID:20044591 NCBI chr14:14,879,698...14,902,510
Ensembl chr14:14,879,717...14,902,510
JBrowse link
G Ccnjl cyclin J-like affects expression ISO Vitamin K 3 affects the expression of CCNJL mRNA CTD PMID:20044591 NCBI chr10:27,995,682...28,053,428
Ensembl chr10:27,995,679...28,053,426
JBrowse link
G Ccnq cyclin Q affects expression ISO Vitamin K 3 affects the expression of CCNQ mRNA CTD PMID:20044591 NCBI chr10:63,646,532...63,647,695
Ensembl chr10:63,646,527...63,647,961
JBrowse link
G Cct2 chaperonin containing TCP1 subunit 2 affects expression ISO Vitamin K 3 affects the expression of CCT2 mRNA CTD PMID:20044591 NCBI chr 7:52,692,725...52,705,478
Ensembl chr 7:52,692,725...52,706,944
JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 affects expression ISO Vitamin K 3 affects the expression of CCT5 mRNA CTD PMID:20044591 NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930
JBrowse link
G Cd1d1 CD1d1 molecule affects expression ISO Vitamin K 3 affects the expression of CD1D mRNA CTD PMID:20829426 NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089
JBrowse link
G Cd36 CD36 molecule affects expression ISO Vitamin K 3 affects the expression of CD36 mRNA CTD PMID:20829426 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cd44 CD44 molecule affects expression ISO Vitamin K 3 affects the expression of CD44 mRNA CTD PMID:20829426 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd48 Cd48 molecule affects expression ISO Vitamin K 3 affects the expression of CD48 mRNA CTD PMID:20829426 NCBI chr13:84,184,884...84,209,144
Ensembl chr13:84,185,532...84,209,142
JBrowse link
G Cd74 CD74 molecule affects expression ISO Vitamin K 3 affects the expression of CD74 mRNA CTD PMID:20829426 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Cd9 CD9 molecule affects expression ISO Vitamin K 3 affects the expression of CD9 mRNA CTD PMID:20044591 PMID:23410634 NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222
JBrowse link
G Cdc14b cell division cycle 14B affects expression ISO Vitamin K 3 affects the expression of CDC14B mRNA CTD PMID:20044591 NCBI chr17:844,686...934,787
Ensembl chr17:844,685...933,235
JBrowse link
G Cdc42ep4 CDC42 effector protein 4 affects expression ISO Vitamin K 3 affects the expression of CDC42EP4 mRNA CTD PMID:23410634 NCBI chr10:98,772,613...98,797,924
Ensembl chr10:98,772,495...98,797,695
JBrowse link
G Cdc45 cell division cycle 45 affects expression ISO Vitamin K 3 affects the expression of CDC45 mRNA CTD PMID:20044591 NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619
JBrowse link
G Cdca5 cell division cycle associated 5 affects expression ISO Vitamin K 3 affects the expression of CDCA5 mRNA CTD PMID:20044591 NCBI chr 1:203,378,550...203,392,027
Ensembl chr 1:203,378,577...203,392,023
JBrowse link
G Cdca7 cell division cycle associated 7 affects expression ISO Vitamin K 3 affects the expression of CDCA7 mRNA CTD PMID:20044591 NCBI chr 3:57,322,718...57,333,353
Ensembl chr 3:57,322,708...57,333,353
JBrowse link
G Cdh1 cadherin 1 increases expression ISO Vitamin K 3 results in increased expression of CDH1 protein CTD PMID:31238027 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdh16 cadherin 16 affects expression ISO Vitamin K 3 affects the expression of CDH16 mRNA CTD PMID:20044591 NCBI chr19:360,824...371,008
Ensembl chr19:360,824...371,007
JBrowse link
G Cdh2 cadherin 2 decreases expression ISO Vitamin K 3 results in decreased expression of CDH2 protein CTD PMID:31238027 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO Vitamin K 3 results in decreased expression of CDK4 mRNA CTD PMID:16010434 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO [sodium arsenite co-treated with Vitamin K 3] results in increased expression of CDKN1A protein; EUK-134 affects the reaction [Vitamin K 3 results in increased expression of CDKN1A protein]; SB 203580 inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in increased expression of CDKN1A protein]
Vitamin K 3 results in increased expression of CDKN1A mRNA; Vitamin K 3 results in increased expression of CDKN1A protein
CTD PMID:12414654 PMID:19082730 PMID:23410634 PMID:25005833 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions ISO [sodium arsenite co-treated with Vitamin K 3] results in increased expression of CDKN1B protein; SB 203580 inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in increased expression of CDKN1B protein] CTD PMID:19082730 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C affects expression ISO Vitamin K 3 affects the expression of CDKN1C mRNA CTD PMID:20044591 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression ISO Vitamin K 3 results in increased expression of CDKN2A mRNA CTD PMID:16010434 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cdt1 chromatin licensing and DNA replication factor 1 affects expression ISO Vitamin K 3 affects the expression of CDT1 mRNA CTD PMID:20044591 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659
JBrowse link
G Cdx1 caudal type homeo box 1 increases expression ISO Vitamin K 3 results in increased expression of CDX1 mRNA CTD PMID:25270620 NCBI chr18:54,472,587...54,490,913
Ensembl chr18:54,473,444...54,490,814
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha affects expression ISO Vitamin K 3 affects the expression of CEBPA mRNA CTD PMID:20044591 PMID:23410634 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cenpa centromere protein A decreases expression ISO Vitamin K 3 results in decreased expression of CENPA mRNA CTD PMID:12414654 NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675
JBrowse link
G Cenpf centromere protein F affects expression ISO Vitamin K 3 affects the expression of CENPF mRNA CTD PMID:20044591 NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
JBrowse link
G Cep95 centrosomal protein 95 affects expression ISO Vitamin K 3 affects the expression of CEP95 mRNA CTD PMID:20044591 NCBI chr10:91,732,111...91,760,095
Ensembl chr10:91,732,111...91,760,092
JBrowse link
G Cfap20 cilia and flagella associated protein 20 affects expression ISO Vitamin K 3 affects the expression of CFAP20 mRNA CTD PMID:20044591 NCBI chr19:9,608,867...9,622,558
Ensembl chr19:9,608,859...9,622,558
JBrowse link
G Cgnl1 cingulin-like 1 affects expression ISO Vitamin K 3 affects the expression of CGNL1 mRNA CTD PMID:20044591 NCBI chr 8:72,273,401...72,424,842
Ensembl chr 8:72,275,645...72,422,917
JBrowse link
G Chek1 checkpoint kinase 1 decreases expression ISO Vitamin K 3 results in decreased expression of CHEK1 mRNA CTD PMID:12414654 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
JBrowse link
G Chka choline kinase alpha affects expression ISO Vitamin K 3 affects the expression of CHKA mRNA CTD PMID:20044591 PMID:23410634 NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516
JBrowse link
G Chpf2 chondroitin polymerizing factor 2 increases expression ISO Vitamin K 3 results in increased expression of CHPF2 mRNA CTD PMID:25270620 NCBI chr 4:10,578,470...10,585,940
Ensembl chr 4:10,580,462...10,585,916
JBrowse link
G Chst15 carbohydrate sulfotransferase 15 affects expression ISO Vitamin K 3 affects the expression of CHST15 mRNA CTD PMID:23410634 NCBI chr 1:187,028,860...187,107,908
Ensembl chr 1:187,028,970...187,107,707
JBrowse link
G Chst7 carbohydrate sulfotransferase 7 affects expression ISO Vitamin K 3 affects the expression of CHST7 mRNA CTD PMID:20044591 NCBI chr  X:2,396,260...2,432,828
Ensembl chr  X:2,393,874...2,432,840
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 affects expression ISO Vitamin K 3 affects the expression of CITED2 mRNA CTD PMID:20044591 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897
JBrowse link
G Ckap5 cytoskeleton associated protein 5 affects expression ISO Vitamin K 3 affects the expression of CKAP5 mRNA CTD PMID:20044591 NCBI chr 3:77,491,195...77,593,300
Ensembl chr 3:77,491,276...77,593,264
JBrowse link
G Ckb creatine kinase B affects expression ISO Vitamin K 3 affects the expression of CKB mRNA CTD PMID:20044591 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
JBrowse link
G Cks1b CDC28 protein kinase regulatory subunit 1B affects expression ISO Vitamin K 3 affects the expression of CKS1B mRNA CTD PMID:20044591 NCBI chr 2:174,833,025...174,837,614
Ensembl chr 2:174,833,050...174,837,636
JBrowse link
G Cldn23 claudin 23 affects expression ISO Vitamin K 3 affects the expression of CLDN23 mRNA CTD PMID:20044591 NCBI chr16:56,413,677...56,415,401
Ensembl chr16:56,413,381...56,415,523
JBrowse link
G Cldn3 claudin 3 affects expression ISO Vitamin K 3 affects the expression of CLDN3 mRNA CTD PMID:20044591 NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001
JBrowse link
G Clip1 CAP-GLY domain containing linker protein 1 affects expression ISO Vitamin K 3 affects the expression of CLIP1 mRNA CTD PMID:20044591 NCBI chr12:32,910,932...33,017,891
Ensembl chr12:32,910,977...33,017,884
JBrowse link
G Clpb ClpB family mitochondrial disaggregase affects expression ISO Vitamin K 3 affects the expression of CLPB mRNA CTD PMID:20044591 NCBI chr 1:156,028,740...156,158,183
Ensembl chr 1:156,028,930...156,168,788
JBrowse link
G Cmbl carboxymethylenebutenolidase homolog affects expression ISO Vitamin K 3 affects the expression of CMBL mRNA CTD PMID:20044591 NCBI chr 2:82,569,257...82,591,007
Ensembl chr 2:82,571,888...82,591,009
JBrowse link
G Cmip c-Maf-inducing protein affects expression ISO Vitamin K 3 affects the expression of CMIP mRNA CTD PMID:20044591 NCBI chr19:45,304,597...45,510,653
Ensembl chr19:45,304,031...45,508,709
JBrowse link
G Cmtm3 CKLF-like MARVEL transmembrane domain containing 3 affects expression ISO Vitamin K 3 affects the expression of CMTM3 mRNA CTD PMID:20044591 NCBI chr19:622,563...630,721
Ensembl chr19:604,458...629,790
JBrowse link
G Cntnap2 contactin associated protein 2 affects expression ISO Vitamin K 3 affects the expression of CNTNAP2 mRNA CTD PMID:20044591 NCBI chr 4:74,109,455...76,366,434
Ensembl chr 4:74,109,472...76,362,027
JBrowse link
G Coa4 cytochrome c oxidase assembly factor 4 homolog affects expression ISO Vitamin K 3 affects the expression of COA4 mRNA CTD PMID:20044591 NCBI chr 1:154,882,199...154,885,445
Ensembl chr 1:154,882,155...154,888,174
JBrowse link
G Coa5 cytochrome C oxidase assembly factor 5 affects expression ISO Vitamin K 3 affects the expression of COA5 mRNA CTD PMID:20044591 NCBI chr 9:39,651,459...39,664,870 JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO Vitamin K 3 results in decreased expression of COL1A1 mRNA CTD PMID:19675304 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col5a2 collagen type V alpha 2 chain affects expression ISO Vitamin K 3 affects the expression of COL5A2 mRNA CTD PMID:20044591 NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154
JBrowse link
G Coro2a coronin 2A affects expression ISO Vitamin K 3 affects the expression of CORO2A mRNA CTD PMID:20044591 NCBI chr 5:60,825,630...60,881,917
Ensembl chr 5:60,828,247...60,859,035
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO [sodium arsenite co-treated with Vitamin K 3] results in increased phosphorylation of CREB1 protein CTD PMID:19082730 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crip1 cysteine rich protein 1 affects expression ISO Vitamin K 3 affects the expression of CRIP1 mRNA CTD PMID:20044591 NCBI chr 6:132,226,746...132,234,620
Ensembl chr 6:132,226,746...132,234,620
JBrowse link
G Cryl1 crystallin, lambda 1 affects expression ISO Vitamin K 3 affects the expression of CRYL1 mRNA CTD PMID:20044591 NCBI chr15:31,427,011...31,545,997
Ensembl chr15:31,427,054...31,545,997
JBrowse link
G Ctbp2 C-terminal binding protein 2 affects expression ISO Vitamin K 3 affects the expression of CTBP2 mRNA CTD PMID:20044591 NCBI chr 1:187,782,064...187,918,115
Ensembl chr 1:187,782,682...187,920,222
JBrowse link
G Ctf1 cardiotrophin 1 multiple interactions
increases expression
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Vitamin K 3 results in increased expression of CTF1 protein]; 2-methoxyestradiol inhibits the reaction [Vitamin K 3 results in increased expression of CTF1 protein]; 6-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo(2,1-b)thiazole inhibits the reaction [Vitamin K 3 results in increased expression of CTF1 protein]; acetovanillone inhibits the reaction [Vitamin K 3 results in increased expression of CTF1 protein]; diphenyleneiodonium inhibits the reaction [Vitamin K 3 results in increased expression of CTF1 protein]; pyrazolanthrone inhibits the reaction [Vitamin K 3 results in increased expression of CTF1 protein]; U 0126 inhibits the reaction [Vitamin K 3 results in increased expression of CTF1 protein]
Vitamin K 3 results in increased expression of CTF1 mRNA; Vitamin K 3 results in increased expression of CTF1 protein
CTD PMID:16507596 NCBI chr 1:182,328,035...182,336,346
Ensembl chr 1:182,328,090...182,333,335
JBrowse link
G Ctnnb1 catenin beta 1 decreases expression ISO Vitamin K 3 results in decreased expression of CTNNB1 protein CTD PMID:31238027 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctnnd1 catenin delta 1 affects expression ISO Vitamin K 3 affects the expression of CTNND1 mRNA CTD PMID:20044591 NCBI chr 3:69,683,328...69,734,550
Ensembl chr 3:69,683,313...69,734,516
JBrowse link
G Ctps1 CTP synthase 1 affects expression ISO Vitamin K 3 affects the expression of CTPS1 mRNA CTD PMID:20044591 NCBI chr 5:134,125,022...134,154,155
Ensembl chr 5:134,125,025...134,154,180
JBrowse link
G Ctr9 CTR9 homolog, Paf1/RNA polymerase II complex component affects expression ISO Vitamin K 3 affects the expression of CTR9 mRNA CTD PMID:20044591 NCBI chr 1:165,137,277...165,167,303
Ensembl chr 1:165,137,215...165,167,303
JBrowse link
G Cul4a cullin 4A affects expression ISO Vitamin K 3 affects the expression of CUL4A mRNA CTD PMID:20044591 NCBI chr16:76,385,298...76,422,316
Ensembl chr16:76,384,546...76,422,330
JBrowse link
G Cxxc5 CXXC finger protein 5 affects expression ISO Vitamin K 3 affects the expression of CXXC5 mRNA CTD PMID:20044591 NCBI chr18:27,427,591...27,458,579
Ensembl chr18:27,427,230...27,458,673
JBrowse link
G Cyb5d2 cytochrome b5 domain containing 2 affects expression ISO Vitamin K 3 affects the expression of CYB5D2 mRNA CTD PMID:23410634 NCBI chr10:57,394,268...57,413,336
Ensembl chr10:57,396,765...57,413,715
JBrowse link
G Cyb5r1 cytochrome b5 reductase 1 affects expression ISO Vitamin K 3 affects the expression of CYB5R1 mRNA CTD PMID:20044591 NCBI chr13:45,849,017...45,855,458
Ensembl chr13:45,849,091...45,855,458
JBrowse link
G Cyba cytochrome b-245 alpha chain increases expression ISO Vitamin K 3 results in increased expression of CYBA protein CTD PMID:16507596 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases activity
increases expression
ISO
EXP
Vitamin K 3 inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]
Vitamin K 3 results in increased activity of CYP1A1 protein
Vitamin K 3 results in increased expression of CYP1A1 mRNA
CTD PMID:15603920 PMID:18493746 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression
increases activity
ISO
EXP
Vitamin K 3 inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]
Vitamin K 3 results in increased expression of CYP1A2 mRNA
Vitamin K 3 results in increased activity of CYP1A2 protein
CTD PMID:15603920 PMID:18493746 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO Vitamin K 3 results in increased expression of CYP1B1 mRNA CTD PMID:12414654 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 affects expression ISO Vitamin K 3 affects the expression of CYP24A1 mRNA CTD PMID:23410634 NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression
multiple interactions
ISO Vitamin K 3 results in decreased expression of CYP2E1 mRNA
[CYP2E1 protein co-treated with Vitamin K 3 co-treated with Arachidonic Acid] results in increased expression of KLF6 protein; [CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein; Buthionine Sulfoximine promotes the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; CAT protein inhibits the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; Dicumarol inhibits the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; S-ethyl glutathione inhibits the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; Vitamin E inhibits the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; Vitamin K 3 promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA alternative form]; Vitamin K 3 promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]
CTD PMID:22486562 PMID:25270620 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 affects expression ISO Vitamin K 3 affects the expression of CYP2J9 mRNA CTD PMID:20829426 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
JBrowse link
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 affects expression ISO Vitamin K 3 affects the expression of CYP2R1 mRNA CTD PMID:20044591 NCBI chr 1:168,749,302...168,798,079
Ensembl chr 1:168,751,038...168,797,759
JBrowse link
G Dbi diazepam binding inhibitor affects expression ISO Vitamin K 3 affects the expression of DBI mRNA CTD PMID:20044591 NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
JBrowse link
G Dcp1b decapping mRNA 1B affects expression ISO Vitamin K 3 affects the expression of DCP1B mRNA CTD PMID:20044591 NCBI chr 4:152,358,267...152,395,747
Ensembl chr 4:152,358,241...152,397,145
JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase multiple interactions
increases metabolic processing
decreases activity
ISO [DCXR protein results in increased metabolism of Vitamin K 3] which results in increased chemical synthesis of Hydrogen Peroxide; [DCXR protein results in increased metabolism of Vitamin K 3] which results in increased chemical synthesis of Superoxides; [Vitamin K 3 co-treated with NADP] binds to DCXR protein; CAT protein inhibits the reaction [[DCXR protein results in increased metabolism of Vitamin K 3] which results in increased chemical synthesis of Hydrogen Peroxide]; Diacetyl inhibits the reaction [[DCXR protein results in increased metabolism of Vitamin K 3] which results in increased chemical synthesis of Superoxides]; Vitamin K 3 inhibits the reaction [[[DCXR protein co-treated with NAD] results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin]
Vitamin K 3 results in decreased activity of DCXR protein
CTD PMID:25526675 PMID:28595002 NCBI chr10:106,006,404...106,008,293 JBrowse link
G Ddc dopa decarboxylase affects expression ISO Vitamin K 3 affects the expression of DDC mRNA CTD PMID:20044591 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
ISO Vitamin K 3 results in increased expression of DDIT3 mRNA; Vitamin K 3 results in increased expression of DDIT3 protein
Metyrapone promotes the reaction [Vitamin K 3 results in increased expression of DDIT3 protein]; S 3483 promotes the reaction [Vitamin K 3 results in increased expression of DDIT3 protein]
CTD PMID:12414654 PMID:19819344 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 affects expression ISO Vitamin K 3 affects the expression of DDIT4 mRNA CTD PMID:23410634 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Ddit4l DNA-damage-inducible transcript 4-like increases expression ISO Vitamin K 3 results in increased expression of DDIT4L mRNA CTD PMID:25270620 NCBI chr 2:226,128,273...226,131,044
Ensembl chr 2:226,128,276...226,131,375
JBrowse link
G Ddx1 DEAD-box helicase 1 affects expression ISO Vitamin K 3 affects the expression of DDX1 mRNA CTD PMID:20044591 NCBI chr 6:35,996,469...36,027,340
Ensembl chr 6:35,996,469...36,027,365
JBrowse link
G Ddx23 DEAD-box helicase 23 affects expression ISO Vitamin K 3 affects the expression of DDX23 mRNA CTD PMID:20044591 NCBI chr 7:129,797,620...129,814,909
Ensembl chr 7:129,797,614...129,814,949
JBrowse link
G Ddx42 DEAD-box helicase 42 increases expression ISO Vitamin K 3 results in increased expression of DDX42 mRNA CTD PMID:12414654 NCBI chr10:91,148,926...91,180,940
Ensembl chr10:91,148,254...91,180,939
JBrowse link
G Ddx47 DEAD-box helicase 47 affects expression ISO Vitamin K 3 affects the expression of DDX47 mRNA CTD PMID:20044591 NCBI chr 4:167,845,652...167,858,115
Ensembl chr 4:167,845,640...167,859,115
JBrowse link
G Defb1 defensin beta 1 affects expression ISO Vitamin K 3 affects the expression of DEFB1 mRNA CTD PMID:20044591 NCBI chr16:70,298,862...70,313,604
Ensembl chr16:70,298,863...70,313,604
JBrowse link
G Depdc7 DEP domain containing 7 affects expression ISO Vitamin K 3 affects the expression of DEPDC7 mRNA CTD PMID:20044591 NCBI chr 3:91,099,111...91,121,152
Ensembl chr 3:91,099,835...91,121,124
JBrowse link
G Deptor DEP domain containing MTOR-interacting protein affects expression ISO Vitamin K 3 affects the expression of DEPTOR mRNA CTD PMID:20044591 NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773
JBrowse link
G Desi2 desumoylating isopeptidase 2 affects expression ISO Vitamin K 3 affects the expression of DESI2 mRNA CTD PMID:20044591 NCBI chr13:89,961,767...90,011,255
Ensembl chr13:89,961,934...90,016,416
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 affects expression ISO Vitamin K 3 affects the expression of DGAT1 mRNA CTD PMID:20044591 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 affects expression ISO Vitamin K 3 affects the expression of DGAT2 mRNA CTD PMID:20044591 PMID:23410634 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Dgkd diacylglycerol kinase, delta affects expression ISO Vitamin K 3 affects the expression of DGKD mRNA CTD PMID:20044591 NCBI chr 9:88,516,686...88,607,349
Ensembl chr 9:88,516,715...88,607,345
JBrowse link
G Dhrs11 dehydrogenase/reductase 11 increases reduction ISO DHRS11 protein results in increased reduction of Vitamin K 3 CTD PMID:30926317 NCBI chr10:69,698,214...69,708,294
Ensembl chr10:69,698,214...69,708,295
JBrowse link
G Dhx35 DEAH-box helicase 35 affects expression ISO Vitamin K 3 affects the expression of DHX35 mRNA CTD PMID:20044591 NCBI chr 3:147,450,178...147,507,473
Ensembl chr 3:147,450,163...147,507,451
JBrowse link
G Dhx9 DExH-box helicase 9 affects expression ISO Vitamin K 3 affects the expression of DHX9 mRNA CTD PMID:20044591 NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069
JBrowse link
G Dipk1b divergent protein kinase domain 1B affects expression ISO Vitamin K 3 affects the expression of DIPK1B mRNA CTD PMID:20044591 NCBI chr 3:9,455,914...9,464,169
Ensembl chr 3:9,456,409...9,464,161
JBrowse link
G Dkc1 dyskerin pseudouridine synthase 1 affects expression ISO Vitamin K 3 affects the expression of DKC1 mRNA CTD PMID:20044591
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 affects expression
increases expression
ISO Vitamin K 3 affects the expression of DKK1 mRNA
Vitamin K 3 results in increased expression of DKK1 mRNA
CTD PMID:12414654 PMID:20044591 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
JBrowse link
G Dlgap5 DLG associated protein 5 affects expression ISO Vitamin K 3 affects the expression of DLGAP5 mRNA CTD PMID:20044591 PMID:23410634 NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518
JBrowse link
G Dmd dystrophin increases response to substance ISO DMD gene mutant form results in increased susceptibility to Vitamin K 3 CTD PMID:10797403 NCBI chr  X:47,272,324...49,504,219
Ensembl chr  X:47,272,331...49,504,207
JBrowse link
G Dmrt1 doublesex and mab-3 related transcription factor 1 increases expression ISO Vitamin K 3 results in increased expression of DMRT1 mRNA CTD PMID:25270620 NCBI chr 1:223,142,859...223,241,333
Ensembl chr 1:223,142,859...223,241,333
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 affects expression ISO Vitamin K 3 affects the expression of DNAJB1 mRNA CTD PMID:20044591 NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458
JBrowse link
G Dnajc14 DnaJ heat shock protein family (Hsp40) member C14 affects expression ISO Vitamin K 3 affects the expression of DNAJC14 mRNA CTD PMID:20044591 NCBI chr 7:1,233,856...1,247,349
Ensembl chr 7:1,235,162...1,248,645
JBrowse link
G Dnm1l dynamin 1-like affects expression ISO Vitamin K 3 affects the expression of DNM1L mRNA CTD PMID:20829426 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta affects expression ISO Vitamin K 3 affects the expression of DNMT3B mRNA CTD PMID:20044591 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124
JBrowse link
G Dnmt3l DNA methyltransferase 3 like decreases expression ISO Vitamin K 3 results in decreased expression of DNMT3L mRNA CTD PMID:25270620 NCBI chr20:10,614,933...10,629,337
Ensembl chr20:10,614,934...10,629,516
JBrowse link
G Dph1 diphthamide biosynthesis 1 affects expression ISO Vitamin K 3 affects the expression of DPH1 mRNA CTD PMID:20044591 NCBI chr10:60,028,081...60,039,764
Ensembl chr10:60,026,048...60,039,850
JBrowse link
G Dph3 diphthamide biosynthesis 3 affects expression ISO Vitamin K 3 affects the expression of DPH3 mRNA CTD PMID:20044591 NCBI chr16:7,288,295...7,293,734
Ensembl chr16:7,282,705...7,291,265
JBrowse link
G Dpm3 dolichyl-phosphate mannosyltransferase subunit 3, regulatory affects expression ISO Vitamin K 3 affects the expression of DPM3 mRNA CTD PMID:20044591 NCBI chr 2:174,676,532...174,677,047
Ensembl chr 2:174,676,363...174,677,668
Ensembl chr15:174,676,363...174,677,668
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase affects expression ISO Vitamin K 3 affects the expression of DPYD mRNA CTD PMID:20829426 NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
JBrowse link
G Dusp1 dual specificity phosphatase 1 affects expression
decreases expression
ISO Vitamin K 3 affects the expression of DUSP1 mRNA
Vitamin K 3 results in decreased expression of DUSP1 mRNA
CTD PMID:23410634 PMID:25270620 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Dusp2 dual specificity phosphatase 2 affects expression ISO Vitamin K 3 affects the expression of DUSP2 mRNA CTD PMID:20044591 NCBI chr 3:114,556,325...114,558,510
Ensembl chr 3:114,556,325...114,558,499
JBrowse link
G Dusp3 dual specificity phosphatase 3 affects expression ISO Vitamin K 3 affects the expression of DUSP3 mRNA CTD PMID:20044591 NCBI chr10:86,920,014...86,933,739
Ensembl chr10:86,920,014...86,933,962
JBrowse link
G Dusp6 dual specificity phosphatase 6 affects expression ISO Vitamin K 3 affects the expression of DUSP6 mRNA CTD PMID:20044591 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
JBrowse link
G Dusp9 dual specificity phosphatase 9 affects expression ISO Vitamin K 3 affects the expression of DUSP9 mRNA CTD PMID:23410634 NCBI chr  X:151,351,897...151,355,822
Ensembl chr  X:151,351,897...151,355,821
JBrowse link
G Dync1h1 dynein cytoplasmic 1 heavy chain 1 affects expression ISO Vitamin K 3 affects the expression of DYNC1H1 mRNA CTD PMID:20044591 NCBI chr 6:129,615,208...129,680,888
Ensembl chr 6:129,609,397...129,680,883
JBrowse link
G Dync1li2 dynein, cytoplasmic 1 light intermediate chain 2 affects expression ISO Vitamin K 3 affects the expression of DYNC1LI2 mRNA CTD PMID:20044591 NCBI chr19:531,783...554,670
Ensembl chr19:531,812...554,670
JBrowse link
G Dyrk2 dual specificity tyrosine phosphorylation regulated kinase 2 affects expression ISO Vitamin K 3 affects the expression of DYRK2 mRNA CTD PMID:20044591 NCBI chr 7:54,348,724...54,381,363
Ensembl chr 7:54,349,610...54,380,106
JBrowse link
G E2f1 E2F transcription factor 1 affects expression ISO Vitamin K 3 affects the expression of E2F1 mRNA CTD PMID:20044591 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
JBrowse link
G E2f3 E2F transcription factor 3 affects expression ISO Vitamin K 3 affects the expression of E2F3 mRNA CTD PMID:20044591 NCBI chr17:34,601,756...34,679,139
Ensembl chr17:34,601,830...34,676,253
JBrowse link
G Ebna1bp2 EBNA1 binding protein 2 affects expression ISO Vitamin K 3 affects the expression of EBNA1BP2 mRNA CTD PMID:20044591 NCBI chr 5:132,148,164...132,152,730
Ensembl chr 5:132,148,143...132,153,267
JBrowse link
G Ecpas Ecm29 proteasome adaptor and scaffold affects expression ISO Vitamin K 3 affects the expression of ECPAS mRNA CTD PMID:20044591 NCBI chr 5:73,601,745...73,714,026
Ensembl chr 5:73,604,533...73,713,860
JBrowse link
G Edc3 enhancer of mRNA decapping 3 affects expression ISO Vitamin K 3 affects the expression of EDC3 mRNA CTD PMID:20044591 NCBI chr 8:58,106,147...58,151,685
Ensembl chr 8:58,106,175...58,151,671
JBrowse link
G Edn1 endothelin 1 increases expression
affects expression
ISO Vitamin K 3 results in increased expression of EDN1 mRNA
Vitamin K 3 affects the expression of EDN1 mRNA
CTD PMID:12414654 PMID:20044591 PMID:23410634 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Efnb2 ephrin B2 decreases expression ISO Vitamin K 3 results in decreased expression of EFNB2 mRNA CTD PMID:25270620 NCBI chr16:80,783,389...80,827,420
Ensembl chr16:80,783,417...80,824,391
JBrowse link
G Egfr epidermal growth factor receptor increases phosphorylation EXP Vitamin K 3 results in increased phosphorylation of EGFR protein CTD PMID:15843167 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 decreases expression ISO Vitamin K 3 results in decreased expression of EGLN3 mRNA CTD PMID:25270620 NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766
JBrowse link
G Egr1 early growth response 1 increases expression
affects expression
ISO Vitamin K 3 results in increased expression of EGR1 mRNA
Vitamin K 3 affects the expression of EGR1 mRNA
CTD PMID:12414654 PMID:20044591 PMID:23410634 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Ehmt1 euchromatic histone lysine methyltransferase 1 affects expression ISO Vitamin K 3 affects the expression of EHMT1 mRNA CTD PMID:20044591 NCBI chr 3:7,580,680...7,729,046
Ensembl chr 3:7,580,683...7,729,007
JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C affects expression ISO Vitamin K 3 affects the expression of EIF3C mRNA CTD PMID:20044591 NCBI chr 1:181,134,604...181,152,489
Ensembl chr 1:181,134,604...181,152,493
JBrowse link
G Eif3j eukaryotic translation initiation factor 3, subunit J affects expression ISO Vitamin K 3 affects the expression of EIF3J mRNA CTD PMID:20044591 NCBI chr 3:108,985,103...109,007,341
Ensembl chr 3:108,985,118...109,007,953
JBrowse link
G Eif4a1 eukaryotic translation initiation factor 4A1 affects expression ISO Vitamin K 3 affects the expression of EIF4A1 mRNA CTD PMID:20044591 NCBI chr10:54,384,345...54,389,855
Ensembl chr10:54,384,347...54,389,858
JBrowse link
G Eif4b eukaryotic translation initiation factor 4B affects expression ISO Vitamin K 3 affects the expression of EIF4B mRNA CTD PMID:20044591 NCBI chr 7:133,206,637...133,228,436 JBrowse link
G Eif4enif1 eukaryotic translation initiation factor 4E nuclear import factor 1 affects expression ISO Vitamin K 3 affects the expression of EIF4ENIF1 mRNA CTD PMID:20044591 NCBI chr14:78,056,115...78,099,846
Ensembl chr14:78,056,297...78,098,793
JBrowse link
G Eif4g2 eukaryotic translation initiation factor 4, gamma 2 affects expression ISO Vitamin K 3 affects the expression of EIF4G2 mRNA CTD PMID:20044591 NCBI chr 1:165,181,433...165,193,583
Ensembl chr 1:165,181,434...165,193,588
JBrowse link
G Elavl1 ELAV like RNA binding protein 1 multiple interactions
increases phosphorylation
ISO [[Vitamin K 3 results in increased phosphorylation of JAK3 protein] which results in increased phosphorylation of and affects the localization of ELAVL1 protein] inhibits the reaction [ELAVL1 protein binds to and results in decreased degradation of SIRT1 mRNA]; [[Vitamin K 3 results in increased phosphorylation of JAK3 protein] which results in increased phosphorylation of and affects the localization of ELAVL1 protein] inhibits the reaction [ELAVL1 protein binds to and results in decreased degradation of VHL mRNA]; [Vitamin K 3 results in increased phosphorylation of JAK3 protein] which results in increased phosphorylation of and affects the localization of ELAVL1 protein; JAK3 protein promotes the reaction [Vitamin K 3 results in increased phosphorylation of ELAVL1 protein]; Janus Kinase Inhibitors inhibits the reaction [Vitamin K 3 results in increased phosphorylation of ELAVL1 protein]; Vitamin K 3 inhibits the reaction [sodium arsenite promotes the reaction [ELAVL1 protein binds to and results in decreased degradation of SIRT1 mRNA]]; Vitamin K 3 inhibits the reaction [sodium arsenite promotes the reaction [ELAVL1 protein binds to and results in decreased degradation of VHL mRNA]] CTD PMID:24106086 NCBI chr12:2,640,936...2,684,787
Ensembl chr12:2,645,061...2,684,784
JBrowse link
G Elavl2 ELAV like RNA binding protein 2 affects expression ISO Vitamin K 3 affects the expression of ELAVL2 mRNA CTD PMID:20829426 NCBI chr 5:105,960,872...106,086,463
Ensembl chr 5:105,960,875...106,109,097
JBrowse link
G Elof1 elongation factor 1 affects expression ISO Vitamin K 3 affects the expression of ELOF1 mRNA CTD PMID:20044591 NCBI chr 8:20,645,336...20,650,888
Ensembl chr 8:20,645,336...20,650,579
JBrowse link
G Emg1 EMG1 N1-specific pseudouridine methyltransferase affects expression ISO Vitamin K 3 affects the expression of EMG1 mRNA CTD PMID:20044591 NCBI chr 4:157,509,258...157,517,540
Ensembl chr 4:157,509,277...157,517,540
JBrowse link
G Emilin1 elastin microfibril interfacer 1 affects expression ISO Vitamin K 3 affects the expression of EMILIN1 mRNA CTD PMID:23410634 NCBI chr 6:25,455,974...25,463,713
Ensembl chr 6:25,445,298...25,463,698
JBrowse link
G Emp2 epithelial membrane protein 2 affects expression ISO Vitamin K 3 affects the expression of EMP2 mRNA CTD PMID:20044591 NCBI chr10:5,360,073...5,394,734
Ensembl chr10:5,360,073...5,394,733
JBrowse link
G Enc1 ectodermal-neural cortex 1 affects expression ISO Vitamin K 3 affects the expression of ENC1 mRNA CTD PMID:20044591 NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713
JBrowse link
G Enosf1 enolase superfamily member 1 affects expression ISO Vitamin K 3 affects the expression of ENOSF1 mRNA CTD PMID:20044591 NCBI chr 9:113,275,267...113,314,842 JBrowse link
G Enpp3 ectonucleotide pyrophosphatase/phosphodiesterase 3 decreases expression ISO Vitamin K 3 results in decreased expression of ENPP3 mRNA CTD PMID:25270620 NCBI chr 1:20,563,700...20,635,044
Ensembl chr 1:20,563,697...20,635,041
JBrowse link
G Ep300 E1A binding protein p300 decreases expression ISO Vitamin K 3 results in decreased expression of EP300 protein CTD PMID:31238027 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Epas1 endothelial PAS domain protein 1 affects expression ISO Vitamin K 3 affects the expression of EPAS1 mRNA CTD PMID:20044591 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression ISO Vitamin K 3 results in increased expression of EPHX1 mRNA CTD PMID:21382384 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Epn2 epsin 2 affects expression ISO Vitamin K 3 affects the expression of EPN2 mRNA CTD PMID:20044591 NCBI chr10:46,197,785...46,259,673
Ensembl chr10:46,197,785...46,259,642
JBrowse link
G Epn3 epsin 3 affects expression ISO Vitamin K 3 affects the expression of EPN3 mRNA CTD PMID:20044591 NCBI chr10:79,438,978...79,449,516
Ensembl chr10:79,438,978...79,447,356
JBrowse link
G Epo erythropoietin multiple interactions ISO [Vitamin K 3 results in increased abundance of Hydrogen Peroxide] which results in decreased expression of EPO protein CTD PMID:7980410 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
JBrowse link
G Eprs1 glutamyl-prolyl-tRNA synthetase 1 affects expression ISO Vitamin K 3 affects the expression of EPRS1 mRNA CTD PMID:20044591 NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966
JBrowse link
G Eps8l2 EPS8-like 2 affects expression ISO Vitamin K 3 affects the expression of EPS8L2 mRNA CTD PMID:20044591 NCBI chr 1:196,446,260...196,471,544
Ensembl chr 1:196,446,287...196,471,541
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 affects expression ISO Vitamin K 3 affects the expression of ERBB3 mRNA CTD PMID:20044591 NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525
JBrowse link
G Erbin erbb2 interacting protein affects expression ISO Vitamin K 3 affects the expression of ERBIN mRNA CTD PMID:20044591 NCBI chr 2:34,926,962...35,028,440
Ensembl chr 2:34,928,863...35,027,852
JBrowse link
G Esr1 estrogen receptor 1 affects binding
multiple interactions
ISO Vitamin K 3 binds to ESR1 protein
Vitamin K 3 inhibits the reaction [Estradiol binds to ESR1 protein]
CTD PMID:15081572 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esrp1 epithelial splicing regulatory protein 1 affects expression ISO Vitamin K 3 affects the expression of ESRP1 mRNA CTD PMID:20044591 NCBI chr 5:24,427,611...24,482,157
Ensembl chr 5:24,428,717...24,482,062
JBrowse link
G Esrp2 epithelial splicing regulatory protein 2 affects expression ISO Vitamin K 3 affects the expression of ESRP2 mRNA CTD PMID:20044591 NCBI chr19:34,034,559...34,041,726
Ensembl chr19:34,034,559...34,041,726
JBrowse link
G Esyt2 extended synaptotagmin 2 affects expression ISO Vitamin K 3 affects the expression of ESYT2 mRNA CTD PMID:20044591 NCBI chr 6:137,219,653...137,312,590
Ensembl chr 6:137,219,707...137,312,590
JBrowse link
G Ets2 ETS proto-oncogene 2, transcription factor affects expression ISO Vitamin K 3 affects the expression of ETS2 mRNA CTD PMID:20044591 NCBI chr11:35,021,536...35,038,322
Ensembl chr11:35,021,596...35,038,319
JBrowse link
G Exosc10 exosome component 10 affects expression ISO Vitamin K 3 affects the expression of EXOSC10 mRNA CTD PMID:20044591 NCBI chr 5:158,995,313...159,018,940
Ensembl chr 5:158,995,313...159,018,940
JBrowse link
G Exosc8 exosome component 8 affects expression ISO Vitamin K 3 affects the expression of EXOSC8 mRNA CTD PMID:20044591 NCBI chr 2:138,930,405...138,937,009
Ensembl chr 2:138,930,405...138,936,928
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit affects expression ISO Vitamin K 3 affects the expression of EZH2 mRNA CTD PMID:20044591 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G Ezr ezrin affects expression ISO Vitamin K 3 affects the expression of EZR mRNA CTD PMID:20044591 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
JBrowse link
G F10 coagulation factor X multiple interactions EXP Vitamin K 3 inhibits the reaction [Ethyl Biscoumacetate results in decreased expression of F10 protein] CTD PMID:6768192 NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141
JBrowse link
G F2rl1 F2R like trypsin receptor 1 affects expression ISO Vitamin K 3 affects the expression of F2RL1 mRNA CTD PMID:23410634 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226
JBrowse link
G F8a1 coagulation factor VIII-associated 1 affects expression ISO Vitamin K 3 affects the expression of F8A1 mRNA CTD PMID:20044591 NCBI chr  X:150,957,357...150,958,871
Ensembl chr  X:150,916,679...150,960,168
JBrowse link
G Fabp1 fatty acid binding protein 1 affects expression ISO Vitamin K 3 affects the expression of FABP1 mRNA CTD PMID:20044591 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
JBrowse link
G Faf1 Fas associated factor 1 affects expression ISO Vitamin K 3 affects the expression of FAF1 mRNA CTD PMID:20044591 NCBI chr 5:124,426,032...124,790,014
Ensembl chr 5:124,426,062...124,789,977
JBrowse link
G Fam107b family with sequence similarity 107, member B affects expression ISO Vitamin K 3 affects the expression of FAM107B mRNA CTD PMID:20044591 NCBI chr17:74,478,608...74,685,027
Ensembl chr17:74,478,608...74,684,989
JBrowse link
G Fam111a FAM111 trypsin like peptidase A affects expression ISO Vitamin K 3 affects the expression of FAM111A mRNA CTD PMID:20044591 NCBI chr 1:209,640,865...209,656,551
Ensembl chr 1:209,640,953...209,656,547
JBrowse link
G Fam174b family with sequence similarity 174, member B affects expression ISO Vitamin K 3 affects the expression of FAM174B mRNA CTD PMID:20044591 NCBI chr 1:127,515,393...127,618,591
Ensembl chr 1:127,514,041...127,596,128
Ensembl chr 1:127,514,041...127,596,128
JBrowse link
G Fam20c FAM20C, golgi associated secretory pathway kinase affects expression ISO Vitamin K 3 affects the expression of FAM20C mRNA CTD PMID:20044591 NCBI chr12:15,826,864...15,885,423
Ensembl chr12:15,826,871...15,884,543
JBrowse link
G Fam217b family with sequence similarity 217, member B affects expression ISO Vitamin K 3 affects the expression of FAM217B mRNA CTD PMID:20044591 NCBI chr 3:165,505,574...165,515,273
Ensembl chr 3:165,501,532...165,513,377
JBrowse link
G Fam222b family with sequence similarity 222, member B affects expression ISO Vitamin K 3 affects the expression of FAM222B mRNA CTD PMID:20044591 NCBI chr10:62,986,571...63,052,350
Ensembl chr10:62,986,571...63,052,350
JBrowse link
G Fam241b family with sequence similarity 241 member B affects expression ISO Vitamin K 3 affects the expression of FAM241B mRNA CTD PMID:20044591 NCBI chr20:30,052,315...30,055,247
Ensembl chr20:30,052,324...30,055,084
JBrowse link
G Fam89b family with sequence similarity 89, member B affects expression ISO Vitamin K 3 affects the expression of FAM89B mRNA CTD PMID:20044591 NCBI chr 1:203,015,772...203,017,890
Ensembl chr 1:203,015,773...203,017,367
JBrowse link
G Fanca FA complementation group A affects expression ISO Vitamin K 3 affects the expression of FANCA mRNA CTD PMID:20044591 NCBI chr19:51,304,126...51,362,586
Ensembl chr19:51,304,021...51,362,527
JBrowse link
G Fancf FA complementation group F affects expression ISO Vitamin K 3 affects the expression of FANCF mRNA CTD PMID:20044591 NCBI chr 1:101,449,120...101,451,936
Ensembl chr 1:101,450,389...101,451,923
JBrowse link
G Farp1 FERM, ARH/RhoGEF and pleckstrin domain protein 1 affects expression ISO Vitamin K 3 affects the expression of FARP1 mRNA CTD PMID:20044591 NCBI chr15:98,124,304...98,363,299
Ensembl chr15:98,182,329...98,363,299
JBrowse link
G Farsb phenylalanyl-tRNA synthetase subunit beta affects expression ISO Vitamin K 3 affects the expression of FARSB mRNA CTD PMID:20044591 NCBI chr 9:79,887,852...79,947,082
Ensembl chr 9:79,887,842...79,947,045
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO Vitamin K 3 results in increased expression of FAS mRNA CTD PMID:12414654 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faxdc2 fatty acid hydroxylase domain containing 2 affects expression ISO Vitamin K 3 affects the expression of FAXDC2 mRNA CTD PMID:20044591 NCBI chr10:42,245,808...42,271,679
Ensembl chr10:42,246,868...42,271,871
JBrowse link
G Fbln1 fibulin 1 affects expression ISO Vitamin K 3 affects the expression of FBLN1 mRNA CTD PMID:20044591 NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075
JBrowse link
G Fbxl15 F-box and leucine-rich repeat protein 15 affects expression ISO Vitamin K 3 affects the expression of FBXL15 mRNA CTD PMID:20044591 NCBI chr 1:245,189,732...245,191,973
Ensembl chr 1:245,189,736...245,192,007
JBrowse link
G Fbxl16 F-box and leucine-rich repeat protein 16 affects expression ISO Vitamin K 3 affects the expression of FBXL16 mRNA CTD PMID:20044591 NCBI chr10:14,829,453...14,841,739
Ensembl chr10:14,829,449...14,840,986
JBrowse link
G Fbxo11 F-box protein 11 affects expression ISO Vitamin K 3 affects the expression of FBXO11 mRNA CTD PMID:20044591 NCBI chr 6:6,486,761...6,562,664
Ensembl chr 6:6,486,015...6,562,662
JBrowse link
G Fbxo21 F-box protein 21 affects expression ISO Vitamin K 3 affects the expression of FBXO21 mRNA CTD PMID:20044591 NCBI chr12:38,570,878...38,605,133
Ensembl chr12:38,571,023...38,605,133
JBrowse link
G Fbxo30 F-box protein 30 increases expression ISO Vitamin K 3 results in increased expression of FBXO30 mRNA CTD PMID:23410634 NCBI chr 1:5,655,341...5,671,558
Ensembl chr 1:5,655,339...5,672,441
JBrowse link
G Fcgr2b Fc gamma receptor 2B affects expression ISO Vitamin K 3 affects the expression of FCGR2B mRNA CTD PMID:20829426 NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778
JBrowse link
G Fcsk fucose kinase affects expression ISO Vitamin K 3 affects the expression of FCSK mRNA CTD PMID:20044591 NCBI chr19:38,849,130...38,874,497
Ensembl chr19:38,854,762...38,874,418
JBrowse link
G Fdxr ferredoxin reductase affects expression
increases expression
ISO Vitamin K 3 affects the expression of FDXR mRNA
Vitamin K 3 results in increased expression of FDXR mRNA
CTD PMID:12414654 PMID:20044591 NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658
JBrowse link
G Fen1 flap structure-specific endonuclease 1 decreases expression ISO Vitamin K 3 results in decreased expression of FEN1 mRNA CTD PMID:12414654 NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003
JBrowse link
G Fermt1 FERM domain containing kindlin 1 affects expression ISO Vitamin K 3 affects the expression of FERMT1 mRNA CTD PMID:20044591 NCBI chr 3:120,171,301...120,213,555
Ensembl chr 3:120,171,561...120,213,555
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 affects expression ISO Vitamin K 3 affects the expression of FGFR2 mRNA CTD PMID:20044591 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
JBrowse link
G Fgg fibrinogen gamma chain increases expression
affects expression
ISO Vitamin K 3 results in increased expression of FGG mRNA
Vitamin K 3 affects the expression of FGG mRNA
CTD PMID:12414654 PMID:20044591 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase increases response to substance ISO FHIT protein results in increased susceptibility to Vitamin K 3 CTD PMID:19622739 NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340
JBrowse link
G Fhl2 four and a half LIM domains 2 affects expression ISO Vitamin K 3 affects the expression of FHL2 mRNA CTD PMID:20044591 NCBI chr 9:45,388,979...45,462,421
Ensembl chr 9:45,388,981...45,431,192
JBrowse link
G Fibp FGF1 intracellular binding protein affects expression ISO Vitamin K 3 affects the expression of FIBP mRNA CTD PMID:20044591 NCBI chr 1:202,768,065...202,772,405
Ensembl chr 1:202,768,078...202,772,399
JBrowse link
G Fip1l1 factor interacting with PAPOLA and CPSF1 affects expression ISO Vitamin K 3 affects the expression of FIP1L1 mRNA CTD PMID:20044591 NCBI chr14:33,615,210...33,675,742
Ensembl chr14:33,617,720...33,675,708
JBrowse link
G Fkbp9 FKBP prolyl isomerase 9 affects expression ISO Vitamin K 3 affects the expression of FKBP9 mRNA CTD PMID:20044591 NCBI chr 4:86,106,256...86,156,723
Ensembl chr 4:86,106,282...86,156,721
JBrowse link
G Flcn folliculin affects expression ISO Vitamin K 3 affects the expression of FLCN mRNA CTD PMID:20044591 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
JBrowse link
G Flnb filamin B decreases expression ISO Vitamin K 3 results in decreased expression of FLNB mRNA CTD PMID:25270620 NCBI chr15:16,961,999...17,095,059
Ensembl chr15:16,962,003...17,095,006
JBrowse link
G Flrt3 fibronectin leucine rich transmembrane protein 3 affects expression ISO Vitamin K 3 affects the expression of FLRT3 mRNA CTD PMID:20044591 NCBI chr 3:127,994,491...128,008,137
Ensembl chr 3:127,994,226...128,007,841
JBrowse link
G Flvcr1 FLVCR choline and heme transporter 1 affects expression ISO Vitamin K 3 affects the expression of FLVCR1 mRNA CTD PMID:20044591 NCBI chr13:102,586,263...102,608,647
Ensembl chr13:102,586,257...102,608,661
JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 affects expression ISO Vitamin K 3 affects the expression of FMR1 mRNA CTD PMID:20829426 NCBI chr  X:147,240,239...147,278,057 JBrowse link
G Fn3krp fructosamine-3-kinase-related protein affects expression ISO Vitamin K 3 affects the expression of FN3KRP mRNA CTD PMID:20044591 NCBI chr10:106,688,413...106,697,137
Ensembl chr10:106,688,439...106,697,134
JBrowse link
G Fndc3a fibronectin type III domain containing 3a affects expression ISO Vitamin K 3 affects the expression of FNDC3A mRNA CTD PMID:20044591 NCBI chr15:47,689,909...47,867,354
Ensembl chr15:47,689,919...47,866,784
JBrowse link
G Focad focadhesin affects expression ISO Vitamin K 3 affects the expression of FOCAD mRNA CTD PMID:20044591 NCBI chr 5:102,564,560...102,886,587
Ensembl chr 5:102,564,598...102,886,582
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO Vitamin K 3 analog results in increased expression of FOS mRNA; Vitamin K 3 results in increased expression of FOS mRNA CTD PMID:19273458 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Foxa1 forkhead box A1 affects expression ISO Vitamin K 3 affects the expression of FOXA1 mRNA CTD PMID:20044591 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
JBrowse link
G Foxa3 forkhead box A3 affects expression ISO Vitamin K 3 affects the expression of FOXA3 mRNA CTD PMID:20044591 NCBI chr 1:78,662,067...78,672,321
Ensembl chr 1:78,662,431...78,672,155
JBrowse link
G Foxc1 forkhead box C1 affects expression ISO Vitamin K 3 affects the expression of FOXC1 mRNA CTD PMID:20044591 NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803
JBrowse link
G Foxd2 forkhead box D2 affects expression ISO Vitamin K 3 affects the expression of FOXD2 mRNA CTD PMID:20044591 NCBI chr 5:128,427,986...128,430,709
Ensembl chr 5:128,429,020...128,430,504
JBrowse link
G Foxj3 forkhead box J3 affects expression ISO Vitamin K 3 affects the expression of FOXJ3 mRNA CTD PMID:20044591 NCBI chr 5:133,140,344...133,228,489
Ensembl chr 5:133,140,884...133,228,489
JBrowse link
G Foxm1 forkhead box M1 decreases expression ISO Vitamin K 3 results in decreased expression of FOXM1 mRNA CTD PMID:12414654 NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684
JBrowse link
G Foxp1 forkhead box P1 affects expression ISO Vitamin K 3 affects the expression of FOXP1 mRNA CTD PMID:20044591 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258
JBrowse link
G Frmd4a FERM domain containing 4A affects expression ISO Vitamin K 3 affects the expression of FRMD4A mRNA CTD PMID:20044591 NCBI chr17:73,667,787...74,258,487
Ensembl chr17:73,667,789...74,258,687
JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions EXP Vitamin K 3 results in decreased expression of and results in decreased secretion of FSHB protein CTD PMID:30536483 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
JBrowse link
G Ftl1 ferritin light chain 1 affects expression
increases expression
multiple interactions
ISO Vitamin K 3 affects the expression of FTL mRNA
Vitamin K 3 results in increased expression of FTL mRNA
Vitamin K 3 promotes the reaction [Iron binds to [FTL protein binds to FTMT protein]]
CTD PMID:12414654 PMID:12644586 PMID:20044591 NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725
JBrowse link
G Ftmt ferritin mitochondrial multiple interactions ISO Vitamin K 3 promotes the reaction [Iron binds to [FTL protein binds to FTMT protein]] CTD PMID:12644586 NCBI chr18:45,758,874...45,760,123
Ensembl chr18:45,758,874...45,760,123
JBrowse link
G Fuom fucose mutarotase affects expression ISO Vitamin K 3 affects the expression of FUOM mRNA CTD PMID:20044591 NCBI chr 1:194,888,535...194,893,046
Ensembl chr 1:194,886,709...194,893,046
JBrowse link
G Fut1 fucosyltransferase 1 affects expression ISO Vitamin K 3 affects the expression of FUT1 mRNA CTD PMID:20044591 NCBI chr 1:96,086,934...96,090,352
Ensembl chr 1:96,086,635...96,090,616
JBrowse link
G Fut8 fucosyltransferase 8 affects expression ISO Vitamin K 3 affects the expression of FUT8 mRNA CTD PMID:20044591 NCBI chr 6:95,949,246...96,176,677
Ensembl chr 6:95,949,991...96,176,677
JBrowse link
G Fzd4 frizzled class receptor 4 affects expression ISO Vitamin K 3 affects the expression of FZD4 mRNA CTD PMID:20044591 NCBI chr 1:143,279,934...143,288,799
Ensembl chr 1:143,280,065...143,285,724
JBrowse link
G Fzd7 frizzled class receptor 7 affects expression ISO Vitamin K 3 affects the expression of FZD7 mRNA CTD PMID:20044591 NCBI chr 9:60,931,433...60,934,252
Ensembl chr 9:60,930,875...60,935,781
JBrowse link
G G0s2 G0/G1switch 2 affects expression ISO Vitamin K 3 affects the expression of G0S2 mRNA CTD PMID:20044591 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
JBrowse link
G G2e3 G2/M-phase specific E3 ubiquitin protein ligase decreases expression ISO Vitamin K 3 results in decreased expression of G2E3 mRNA CTD PMID:25270620 NCBI chr 6:68,763,847...68,795,305
Ensembl chr 6:68,764,185...68,793,924
JBrowse link
G Gaa alpha glucosidase affects expression ISO Vitamin K 3 affects the expression of GAA mRNA CTD PMID:20044591 NCBI chr10:104,529,673...104,546,836
Ensembl chr10:104,529,747...104,546,836
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta affects expression ISO Vitamin K 3 affects the expression of GADD45B mRNA CTD PMID:23410634 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
JBrowse link
G Gal galanin and GMAP prepropeptide affects expression ISO Vitamin K 3 affects the expression of GAL mRNA CTD PMID:20044591 NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
JBrowse link
G Gal3st1 galactose-3-O-sulfotransferase 1 affects expression ISO Vitamin K 3 affects the expression of GAL3ST1 mRNA CTD PMID:20044591 NCBI chr14:78,868,049...78,886,402
Ensembl chr14:78,870,793...78,886,388
JBrowse link
G Galm galactose mutarotase affects expression ISO Vitamin K 3 affects the expression of GALM mRNA CTD PMID:20044591 NCBI chr 6:14,837,540...14,889,484
Ensembl chr 6:14,837,548...14,889,310
JBrowse link
G Galnt11 polypeptide N-acetylgalactosaminyltransferase 11 affects expression ISO Vitamin K 3 affects the expression of GALNT11 mRNA CTD PMID:20044591 NCBI chr 4:9,837,629...9,871,141
Ensembl chr 4:9,837,629...9,871,140
JBrowse link
G Gap43 growth associated protein 43 increases expression ISO Vitamin K 3 analog results in increased expression of GAP43 mRNA CTD PMID:19273458 NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045
JBrowse link
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase affects expression ISO Vitamin K 3 affects the expression of GART mRNA CTD PMID:20044591 NCBI chr11:30,864,896...30,891,125
Ensembl chr11:30,865,889...30,891,125
JBrowse link
G Gata6 GATA binding protein 6 affects expression ISO Vitamin K 3 affects the expression of GATA6 mRNA CTD PMID:20044591 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases activity
increases expression
multiple interactions
ISO Vitamin K 3 results in increased activity of GCLC protein
Vitamin K 3 results in increased expression of GCLC mRNA
Dactinomycin inhibits the reaction [Vitamin K 3 results in increased expression of GCLC mRNA]
CTD PMID:11972604 PMID:23410634 PMID:25270620 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Vitamin K 3 results in increased expression of GCLM mRNA CTD PMID:12414654 PMID:23410634 PMID:25270620 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type increases expression ISO Vitamin K 3 results in increased expression of GCNT3 mRNA CTD PMID:23410634 NCBI chr 8:70,689,173...70,696,476
Ensembl chr 8:70,686,844...70,699,562
JBrowse link
G Gdf15 growth differentiation factor 15 affects expression
increases expression
ISO Vitamin K 3 affects the expression of GDF15 mRNA
Vitamin K 3 results in increased expression of GDF15 mRNA
CTD PMID:12414654 PMID:20044591 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gdi1 GDP dissociation inhibitor 1 affects expression ISO Vitamin K 3 affects the expression of GDI1 mRNA CTD PMID:20044591 NCBI chr  X:152,087,611...152,094,274
Ensembl chr  X:152,087,444...152,094,272
JBrowse link
G Gdi2 GDP dissociation inhibitor 2 affects expression ISO Vitamin K 3 affects the expression of GDI2 mRNA CTD PMID:20044591 NCBI chr17:66,649,616...66,676,299
Ensembl chr17:66,649,619...66,676,366
JBrowse link
G Gdpd5 glycerophosphodiester phosphodiesterase domain containing 5 affects expression ISO Vitamin K 3 affects the expression of GDPD5 mRNA CTD PMID:23410634 NCBI chr 1:153,679,718...153,761,452
Ensembl chr 1:153,679,718...153,761,446
JBrowse link
G Gemin6 gem (nuclear organelle) associated protein 6 affects expression ISO Vitamin K 3 affects the expression of GEMIN6 mRNA CTD PMID:20044591 NCBI chr 6:14,786,090...14,790,617
Ensembl chr 6:14,786,070...14,790,612
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 decreases expression
multiple interactions
EXP Vitamin K 3 results in decreased expression of GGT1 mRNA alternative form
Acetylcysteine inhibits the reaction [Vitamin K 3 results in increased activity of GGT1 protein]; Vitamin K 3 results in increased expression of and results in increased activity of GGT1 protein
CTD PMID:12030384 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
G Ghr growth hormone receptor affects expression ISO Vitamin K 3 affects the expression of GHR mRNA CTD PMID:20829426 NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735
JBrowse link
G Gigyf2 GRB10 interacting GYF protein 2 affects expression ISO Vitamin K 3 affects the expression of GIGYF2 mRNA CTD PMID:20044591 NCBI chr 9:88,001,212...88,127,040
Ensembl chr 9:88,001,301...88,125,715
JBrowse link
G Gipc2 GIPC PDZ domain containing family, member 2 increases expression ISO Vitamin K 3 results in increased expression of GIPC2 mRNA CTD PMID:25270620 NCBI chr 2:241,030,764...241,110,236
Ensembl chr 2:241,030,770...241,110,236
JBrowse link
G Gja1 gap junction protein, alpha 1 affects expression ISO Vitamin K 3 affects the expression of GJA1 mRNA CTD PMID:20829426 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Glcci1 glucocorticoid induced 1 affects expression ISO Vitamin K 3 affects the expression of GLCCI1 mRNA CTD PMID:20044591 NCBI chr 4:36,307,956...36,635,614
Ensembl chr 4:36,307,903...36,635,612
JBrowse link
G Gldc glycine decarboxylase affects expression ISO Vitamin K 3 affects the expression of GLDC mRNA CTD PMID:20044591 NCBI chr 1:227,883,249...227,962,119
Ensembl chr 1:227,883,249...227,962,097
JBrowse link
G Glg1 golgi glycoprotein 1 affects expression ISO Vitamin K 3 affects the expression of GLG1 mRNA CTD PMID:20044591 NCBI chr19:39,124,892...39,224,178
Ensembl chr19:39,124,641...39,224,178
JBrowse link
G Glrx glutaredoxin increases expression ISO Vitamin K 3 results in increased expression of GLRX mRNA CTD PMID:12414654 NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
JBrowse link
G Gls glutaminase affects expression ISO Vitamin K 3 affects the expression of GLS mRNA CTD PMID:20044591 NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900
JBrowse link
G Glt8d1 glycosyltransferase 8 domain containing 1 affects expression ISO Vitamin K 3 affects the expression of GLT8D1 mRNA CTD PMID:20044591 NCBI chr16:6,192,269...6,207,227
Ensembl chr16:6,192,300...6,207,229
JBrowse link
G Glyctk glycerate kinase affects expression ISO Vitamin K 3 affects the expression of GLYCTK mRNA CTD PMID:20044591 NCBI chr 8:106,795,461...106,802,675
Ensembl chr 8:106,797,343...106,802,397
JBrowse link
G Gnai1 G protein subunit alpha i1 affects expression ISO Vitamin K 3 affects the expression of GNAI1 mRNA CTD PMID:23410634 NCBI chr 4:16,814,000...16,898,119
Ensembl chr 4:16,814,001...16,896,417
JBrowse link
G Gnaz G protein subunit alpha z affects expression ISO Vitamin K 3 affects the expression of GNAZ mRNA CTD PMID:20044591 NCBI chr20:13,643,473...13,694,240
Ensembl chr20:13,644,640...13,669,907
JBrowse link
G Gnpat glyceronephosphate O-acyltransferase affects expression ISO Vitamin K 3 affects the expression of GNPAT mRNA CTD PMID:20044591 NCBI chr19:52,822,326...52,848,872
Ensembl chr19:52,822,319...52,852,361
JBrowse link
G Golga3 golgin A3 affects expression ISO Vitamin K 3 affects the expression of GOLGA3 mRNA CTD PMID:20044591 NCBI chr12:46,452,409...46,500,509
Ensembl chr12:46,454,870...46,500,509
JBrowse link
G Gon4l gon-4 like affects expression ISO Vitamin K 3 affects the expression of GON4L mRNA CTD PMID:20044591 NCBI chr 2:174,233,461...174,306,636
Ensembl chr 2:174,233,461...174,306,634
JBrowse link
G Gopc golgi associated PDZ and coiled-coil motif containing affects expression ISO Vitamin K 3 affects the expression of GOPC mRNA CTD PMID:20044591 NCBI chr20:31,727,617...31,776,904
Ensembl chr20:31,727,620...31,776,903
JBrowse link
G Gpank1 G patch domain and ankyrin repeats 1 affects expression ISO Vitamin K 3 affects the expression of GPANK1 mRNA CTD PMID:20044591 NCBI chr20:3,697,641...3,700,814
Ensembl chr20:3,697,641...3,700,858
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression ISO Vitamin K 3 results in increased expression of GPAT3 mRNA CTD PMID:23410634 NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
JBrowse link
G Gpbp1 GC-rich promoter binding protein 1 affects expression ISO Vitamin K 3 affects the expression of GPBP1 mRNA CTD PMID:20829426 NCBI chr 2:43,023,504...43,091,146
Ensembl chr 2:43,023,504...43,090,907
JBrowse link
G Gpr160 G protein-coupled receptor 160 affects expression ISO Vitamin K 3 affects the expression of GPR160 mRNA CTD PMID:20044591 NCBI chr 2:112,483,364...112,563,072
Ensembl chr 2:112,484,935...112,563,148
JBrowse link
G Gprc5a G protein-coupled receptor, class C, group 5, member A affects expression ISO Vitamin K 3 affects the expression of GPRC5A mRNA CTD PMID:20044591 NCBI chr 4:167,903,542...167,922,276
Ensembl chr 4:167,903,542...167,922,260
JBrowse link
G Gprc5b G protein-coupled receptor, class C, group 5, member B affects expression ISO Vitamin K 3 affects the expression of GPRC5B mRNA CTD PMID:20044591 NCBI chr 1:173,316,904...173,340,933
Ensembl chr 1:173,316,907...173,340,932
JBrowse link
G Gprc5c G protein-coupled receptor, class C, group 5, member C affects expression ISO Vitamin K 3 affects the expression of GPRC5C mRNA CTD PMID:20044591 NCBI chr10:99,886,900...99,908,928
Ensembl chr10:99,887,077...99,908,926
JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 affects expression ISO Vitamin K 3 affects the expression of GPT2 mRNA CTD PMID:20044591 NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610
JBrowse link
G Gpx1 glutathione peroxidase 1 decreases response to substance ISO GPX1 protein results in decreased susceptibility to Vitamin K 3 CTD PMID:1939125 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression ISO Vitamin K 3 results in increased expression of GPX2 mRNA CTD PMID:12414654 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Grid1 glutamate ionotropic receptor delta type subunit 1 affects expression ISO Vitamin K 3 affects the expression of GRID1 mRNA CTD PMID:20044591 NCBI chr16:10,138,564...10,885,803
Ensembl chr16:10,138,925...10,885,808
JBrowse link
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C increases expression ISO Vitamin K 3 results in increased expression of GRIN2C mRNA CTD PMID:12414654 NCBI chr10:100,488,430...100,507,083
Ensembl chr10:100,488,431...100,506,427
JBrowse link
G Grk5 G protein-coupled receptor kinase 5 affects expression ISO Vitamin K 3 affects the expression of GRK5 mRNA CTD PMID:20044591 NCBI chr 1:260,028,269...260,223,699
Ensembl chr 1:260,028,242...260,218,701
JBrowse link
G Grn granulin precursor affects expression ISO Vitamin K 3 affects the expression of GRN mRNA CTD PMID:20044591