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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:oneirogen
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Accession:CHEBI:146270 term browser browse the term
Definition:Any substance that produces or enhances dream-like states of consciousness.
Synonyms:related_synonym: oneirogens
 xref: Wikipedia:Oneirogen



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atropine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity
ISO Atropine inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Atropine results in decreased activity of ABCB11 protein
CTD PMID:24014644 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase multiple interactions ISO [Parathion co-treated with Atropine] results in increased expression of ABL1 mRNA CTD PMID:17390078 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Ache acetylcholinesterase multiple interactions ISO
EXP
Atropine inhibits the reaction [[Organophosphorus Compounds results in decreased activity of ACHE protein] which results in increased abundance of Acetylcholine]; Atropine inhibits the reaction [Carbachol results in increased metabolism of and results in increased secretion of ACHE protein]; Atropine inhibits the reaction [Paraoxon results in increased expression of ACHE protein]
[Atropine co-treated with Obidoxime Chloride] inhibits the reaction [Paraoxon results in decreased activity of ACHE protein]; [Methyl Parathion co-treated with pralidoxime co-treated with Atropine] results in decreased expression of ACHE protein; [Paraoxon co-treated with pralidoxime co-treated with Atropine] results in decreased activity of ACHE protein; [pralidoxime co-treated with Atropine] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; [tariquidar co-treated with asoxime chloride co-treated with Atropine] inhibits the reaction [Soman results in decreased activity of ACHE protein]; Atropine inhibits the reaction [Methyl Parathion results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [[Paraoxon co-treated with pralidoxime co-treated with Atropine] results in decreased activity of ACHE protein]; pralidoxime promotes the reaction [[Atropine co-treated with Curcumin] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]]
[1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; [[1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide co-treated with cucurbit(7)uril] co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Atropine inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Atropine promotes the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]; Atropine promotes the reaction [haloxon results in increased phosphorylation of ACHE protein]; Atropine promotes the reaction [Paraoxon results in increased phosphorylation of ACHE protein]
CTD PMID:2241428 PMID:10421444 PMID:17963125 PMID:20105433 PMID:21600273 More... NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Adcy5 adenylate cyclase 5 increases response to substance ISO ADCY5 protein results in increased susceptibility to Atropine CTD PMID:12869393 NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974
JBrowse link
G Aqp5 aquaporin 5 multiple interactions ISO Atropine inhibits the reaction [Pilocarpine affects the localization of AQP5 protein] CTD PMID:26208470 NCBI chr 7:130,722,675...130,726,207
Ensembl chr 7:130,721,748...130,726,209
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the expression of BAX mRNA] CTD PMID:21971501 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member multiple interactions ISO Atropine inhibits the reaction [[oxotremorine M co-treated with wortmannin] inhibits the reaction [oxophenylarsine results in increased phosphorylation of BCAR1 protein]] CTD PMID:10537051 NCBI chr19:39,679,215...39,713,907
Ensembl chr19:39,679,204...39,713,907
JBrowse link
G Bche butyrylcholinesterase multiple interactions EXP
ISO
[Atropine co-treated with pralidoxime] results in decreased expression of BCHE protein; [Methyl Parathion co-treated with pralidoxime co-treated with Atropine] results in decreased expression of BCHE protein
[BCHE protein co-treated with asoxime chloride co-treated with pro-diazepam co-treated with Atropine] results in decreased susceptibility to VX
CTD PMID:17963125 PMID:22981459 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Bdkrb2 bradykinin receptor B2 multiple interactions ISO BDKRB2 affects the susceptibility to [Propranolol co-treated with Atropine] CTD PMID:10614985 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497
JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions EXP Atropine inhibits the reaction [Carbon Tetrachloride results in increased expression of BMP6 mRNA] CTD PMID:18472332 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E multiple interactions EXP Atropine inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]] CTD PMID:12663092 NCBI chr13:66,574,659...67,063,443
Ensembl chr13:66,581,920...66,894,450
JBrowse link
G Calca calcitonin-related polypeptide alpha affects activity EXP Atropine affects the activity of CALCA protein CTD PMID:7906887 PMID:10075105 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Casp3 caspase 3 increases expression EXP Atropine results in increased expression of CASP3 mRNA CTD PMID:19815060 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CCL5 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CCL5 protein] CTD PMID:22245128 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccna1 cyclin A1 increases expression
multiple interactions
ISO Atropine results in increased expression of CCNA1 mRNA
[Parathion co-treated with Atropine] results in increased expression of CCNA1 mRNA
CTD PMID:17390078 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
JBrowse link
G Ccnd3 cyclin D3 multiple interactions ISO [Parathion co-treated with Atropine] results in increased expression of CCND3 mRNA CTD PMID:17390078 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Ccne1 cyclin E1 increases expression
multiple interactions
ISO Atropine results in increased expression of CCNE1 mRNA
[Parathion co-treated with Atropine] results in increased expression of CCNE1 mRNA
CTD PMID:17390078 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Ccne2 cyclin E2 multiple interactions
increases expression
ISO [Parathion co-treated with Atropine] results in increased expression of CCNE2 mRNA
Atropine results in increased expression of CCNE2 mRNA
CTD PMID:17390078 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Cd40 CD40 molecule multiple interactions ISO Atropine inhibits the reaction [Carbachol results in increased expression of CD40 protein] CTD PMID:16879495 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cdc20 cell division cycle 20 multiple interactions
increases expression
ISO [Parathion co-treated with Atropine] results in increased expression of CDC20 mRNA
Atropine results in increased expression of CDC20 mRNA
CTD PMID:17390078 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
JBrowse link
G Cdc6 cell division cycle 6 multiple interactions ISO [Parathion co-treated with Atropine] results in increased expression of CDC6 mRNA CTD PMID:17390078 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions
increases expression
ISO [Parathion co-treated with Atropine] results in increased expression of CDK1 mRNA
Atropine results in increased expression of CDK1 mRNA
CTD PMID:17390078 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Ces1d carboxylesterase 1D multiple interactions ISO Atropine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate] CTD PMID:9311626 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 multiple interactions
decreases activity
ISO Atropine binds to and results in decreased activity of CHRM1 protein; Atropine inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]
Atropine results in decreased activity of CHRM1 protein
Atropine affects the reaction [muscarinic toxin 7 binds to CHRM1 protein]
CTD PMID:16439611 PMID:18316702 PMID:31830555 NCBI chr 1:205,567,226...205,583,001
Ensembl chr 1:205,567,220...205,582,356
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 multiple interactions ISO Atropine binds to and results in decreased activity of CHRM2 protein CTD PMID:15140916 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 multiple interactions
decreases activity
ISO Atropine binds to and results in decreased activity of CHRM3 protein; Atropine inhibits the reaction [Carbachol results in increased activity of CHRM3 protein]
Atropine results in decreased activity of CHRM3 protein
CTD PMID:15140916 PMID:20708676 PMID:31830555 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278
JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 multiple interactions
affects binding
ISO [WIN 62577 co-treated with Quinuclidinyl Benzilate] inhibits the reaction [Atropine binds to CHRM4 protein] CTD PMID:16709648 NCBI chr 3:77,893,425...77,901,166
Ensembl chr 3:77,893,425...77,901,159
JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 multiple interactions ISO Atropine inhibits the reaction [Acetylcholine results in increased activity of CHRM5 protein] CTD PMID:31323226 NCBI chr 3:99,284,846...99,337,252
Ensembl chr 3:99,284,846...99,337,252
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions
affects binding
ISO
EXP
Atropine promotes the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]]
Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNA4 mRNA]]; Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNA4 protein]]
Atropine binds to [CHRNA4 protein binds to CHRNB2 protein]
CTD PMID:15733544 PMID:21791372 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit affects binding
multiple interactions
ISO
EXP
Atropine binds to [CHRNA4 protein binds to CHRNB2 protein]
Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNB2 mRNA]]; Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNB2 protein]]
Atropine promotes the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]]
CTD PMID:15733544 PMID:21791372 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the phosphorylation of CREB1 protein] CTD PMID:21971501 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crh corticotropin releasing hormone multiple interactions EXP
ISO
Atropine inhibits the reaction [acephate results in increased expression of CRH mRNA]; Atropine inhibits the reaction [acephate results in increased secretion of CRH protein]; Atropine inhibits the reaction [methamidophos results in increased expression of CRH mRNA]; Atropine inhibits the reaction [methamidophos results in increased secretion of CRH protein]
[Atropine co-treated with SR 140333 co-treated with SR 48968] results in decreased activity of CRH protein
CTD PMID:12039681 PMID:12906840 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of CTNNB1 protein mutant form]; Atropine inhibits the reaction [Parathion results in increased expression of CTNNB1 protein] CTD PMID:17390078 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CXCL1 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CXCL1 protein] CTD PMID:22245128 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Dvl2 dishevelled segment polarity protein 2 multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of DVL2 protein] CTD PMID:17390078 NCBI chr10:54,723,356...54,732,823
Ensembl chr10:54,723,411...54,732,820
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO EDN1 protein results in decreased activity of [Atropine co-treated with Histamine] CTD PMID:12906840 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 multiple interactions ISO atropine inhibits the reaction [carbachol decreases phosphorylation of EEF2 protein in colon cancer cells] RGD PMID:31227218 RGD:153298919 NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of EGFR protein] CTD PMID:17390078 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egr1 early growth response 1 multiple interactions EXP Atropine inhibits the reaction [Pilocarpine results in increased expression of EGR1 mRNA] CTD PMID:7968354 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Egr2 early growth response 2 multiple interactions EXP Atropine inhibits the reaction [Pilocarpine results in increased expression of EGR2 mRNA] CTD PMID:7968354 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
JBrowse link
G Ezr ezrin multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of EZR protein] CTD PMID:17390078 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
JBrowse link
G F2 coagulation factor II, thrombin multiple interactions ISO [Paraoxon co-treated with Atropine co-treated with Obidoxime Chloride] results in decreased expression of F2 mRNA; [Paraoxon co-treated with Atropine co-treated with Obidoxime Chloride] results in increased activity of F2 protein CTD PMID:30515700 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G F2r coagulation factor II (thrombin) receptor multiple interactions ISO [Paraoxon co-treated with Atropine co-treated with Obidoxime Chloride] results in increased expression of F2R protein CTD PMID:30515700 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
EXP
ISO
Atropine results in increased expression of FOS protein
Atropine inhibits the reaction [Paraoxon results in increased expression of FOS mRNA]
[asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased expression of FOS protein]; Atropine inhibits the reaction [Pilocarpine results in increased expression of FOS mRNA]
CTD PMID:7968354 PMID:8281324 PMID:21787676 PMID:21971501 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide multiple interactions EXP Atropine inhibits the reaction [[Pentobarbital co-treated with L-pyroglutamyl-L-histidyl-3,3-dimethylprolinamide] results in increased expression of GHRL protein] CTD PMID:16959836 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621
JBrowse link
G Glra1 glycine receptor, alpha 1 multiple interactions ISO Atropine binds to and results in decreased activity of GLRA1 protein CTD PMID:15081878 NCBI chr10:39,625,853...39,727,897
Ensembl chr10:39,629,459...39,727,162
JBrowse link
G Grm4 glutamate metabotropic receptor 4 multiple interactions ISO Atropine inhibits the reaction [[Carbachol results in increased activity of [GRM4 protein binds to KCNJ3 protein]] which results in increased import of Thallium] CTD PMID:18171729 NCBI chr20:5,484,172...5,572,821
Ensembl chr20:5,481,124...5,572,821
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of ICAM1 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of ICAM1 protein] CTD PMID:22245128 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of IL1B mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of IL1B protein] CTD PMID:22245128 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Atropine co-treated with Ketamine] inhibits the reaction [Soman results in increased expression of IL6 mRNA]; [Atropine co-treated with Ketamine] inhibits the reaction [Soman results in increased expression of IL6 protein] CTD PMID:22245128 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the phosphorylation of JUN protein] CTD PMID:21971501 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Atropine inhibits the reaction [Pilocarpine results in increased expression of JUNB mRNA] CTD PMID:7968354 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 multiple interactions ISO Atropine inhibits the reaction [[Carbachol results in increased activity of [GRM4 protein binds to KCNJ3 protein]] which results in increased import of Thallium] CTD PMID:18171729 NCBI chr 3:39,944,896...40,106,646
Ensembl chr 3:39,945,351...40,109,124
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of KIT protein] CTD PMID:17390078 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Ltf lactotransferrin multiple interactions ISO Atropine inhibits the reaction [methylcholine results in increased secretion of LTF protein] CTD PMID:11112886 NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK1 protein] CTD PMID:21971501 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions EXP [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK14 protein] CTD PMID:21971501 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK3 protein] CTD PMID:21971501 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK8 protein] CTD PMID:21971501 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 multiple interactions
increases expression
ISO [Parathion co-treated with Atropine] results in increased expression of MCM4 mRNA
Atropine results in increased expression of MCM4 mRNA
CTD PMID:17390078 NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression
multiple interactions
ISO Atropine results in increased expression of MCM6 mRNA
[Parathion co-treated with Atropine] results in increased expression of MCM6 mRNA
CTD PMID:17390078 NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960
JBrowse link
G Nefh neurofilament heavy chain affects expression EXP Atropine affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 increases expression ISO Atropine results in increased expression of NLRP3 mRNA CTD PMID:28138970 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP Atropine inhibits the reaction [Indomethacin results in increased activity of NOS2 protein]; Atropine inhibits the reaction [Indomethacin results in increased expression of NOS2 mRNA] CTD PMID:15610444 PMID:16944022 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Notch4 notch receptor 4 multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of NOTCH4 protein] CTD PMID:17390078 NCBI chr20:4,160,362...4,184,466
Ensembl chr20:4,160,445...4,184,465
JBrowse link
G Nppa natriuretic peptide A affects activity EXP Atropine affects the activity of NPPA protein modified form CTD PMID:1363893 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Oprl1 opioid related nociceptin receptor 1 multiple interactions EXP Atropine inhibits the reaction [PNOC protein binds to and results in increased activity of OPRL1 protein] CTD PMID:12007927 NCBI chr 3:168,831,934...168,839,920
Ensembl chr 3:168,834,003...168,839,920
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO Atropine inhibits the reaction [Malathion results in increased expression of PCNA]; Atropine inhibits the reaction [Parathion results in increased expression of PCNA] CTD PMID:12762645 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pnoc prepronociceptin multiple interactions EXP Atropine inhibits the reaction [PNOC protein binds to and results in increased activity of OPRL1 protein] CTD PMID:12007927 NCBI chr15:39,624,635...39,652,463
Ensembl chr15:39,624,641...39,651,867
JBrowse link
G Pomc proopiomelanocortin multiple interactions EXP Atropine inhibits the reaction [Acetylcholine results in increased expression of POMC protein] CTD PMID:7588217 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO [Atropine co-treated with Glucose] binds to PPARA protein; Atropine inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]] CTD PMID:18812576 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP Atropine affects the reaction [Indomethacin results in increased expression of PTGS2]; Atropine inhibits the reaction [Indomethacin results in increased expression of PTGS2 mRNA]; Atropine inhibits the reaction [Indomethacin results in increased expression of PTGS2]; Atropine inhibits the reaction [SC 560 results in increased expression of PTGS2 mRNA] CTD PMID:15104355 PMID:15610444 PMID:16259740 PMID:16804302 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptk2 protein tyrosine kinase 2 multiple interactions ISO Atropine inhibits the reaction [oxotremorine M inhibits the reaction [[wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein]]; Atropine inhibits the reaction [oxotremorine M inhibits the reaction [[wortmannin co-treated with oxophenylarsine] results in increased phosphorylation of PTK2 protein]]; Atropine inhibits the reaction [oxotremorine M promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with wortmannin] results in increased phosphorylation of PTK2 protein]] CTD PMID:10537051 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Pxn paxillin multiple interactions ISO Atropine inhibits the reaction [[oxotremorine M co-treated with wortmannin] inhibits the reaction [oxophenylarsine results in increased phosphorylation of PXN protein]] CTD PMID:10537051 NCBI chr12:41,060,791...41,107,952
Ensembl chr12:41,060,791...41,107,931
JBrowse link
G Rac3 Rac family small GTPase 3 multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of RAC3 protein] CTD PMID:17390078 NCBI chr10:106,002,808...106,005,243
Ensembl chr10:105,993,087...106,005,260
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the phosphorylation of RELA protein] CTD PMID:21971501 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rhoa ras homolog family member A multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of RHOA protein] CTD PMID:17390078 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Slc22a1 solute carrier family 22 member 1 multiple interactions ISO Atropine inhibits the reaction [SLC22A1 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Atropine inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:16263091 PMID:21641380 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Atropine inhibits the reaction [SLC22A2 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Atropine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]; Atropine inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:16263091 PMID:21599003 PMID:23770354 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Slc22a3 solute carrier family 22 member 3 increases uptake
multiple interactions
ISO SLC22A3 protein results in increased uptake of Atropine
Atropine inhibits the reaction [SLC22A3 protein results in increased transport of 1-Methyl-4-phenylpyridinium]
CTD PMID:16263091 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612
JBrowse link
G Slc22a4 solute carrier family 22 member 4 multiple interactions ISO Atropine inhibits the reaction [SLC22A4 protein results in increased uptake of Tetraethylammonium] CTD PMID:21641380 NCBI chr10:38,133,333...38,179,932
Ensembl chr10:38,133,322...38,179,720
JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO Atropine inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,034,115...46,088,617
Ensembl chr10:46,034,122...46,087,637
JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO Atropine inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:45,990,806...46,033,937
Ensembl chr10:45,991,095...46,033,904
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Atropine results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions ISO [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of SOCS3 mRNA] CTD PMID:22245128 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
G Spn sialophorin increases response to substance ISO SPN protein results in increased susceptibility to Atropine CTD PMID:18711009 NCBI chr 1:181,746,937...181,759,564
Ensembl chr 1:181,746,429...181,759,628
JBrowse link
G Tat tyrosine aminotransferase multiple interactions EXP [Atropine co-treated with Obidoxime Chloride co-treated with Diazepam] inhibits the reaction [Dichlorvos results in increased expression of TAT protein] CTD PMID:7761789 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP Atropine inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA] CTD PMID:18472332 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of TNF mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of TNF protein] CTD PMID:22245128 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO Atropine inhibits the reaction [Malathion results in increased expression of TP53 protein]; Atropine inhibits the reaction [Parathion results in increased expression of TP53 protein] CTD PMID:12762645 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Trio trio Rho guanine nucleotide exchange factor multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of TRIO protein] CTD PMID:17390078 NCBI chr 2:78,505,069...78,801,384
Ensembl chr 2:78,505,070...78,803,135
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 decreases response to substance ISO TRPA1 gene mutant form results in decreased susceptibility to Atropine CTD PMID:29627347 NCBI chr 5:4,379,862...4,434,133
Ensembl chr 5:4,379,999...4,433,570
JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions EXP [pralidoxime co-treated with Atropine] inhibits the reaction [methamidophos results in decreased expression of TSHB protein] CTD PMID:15891268 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559
JBrowse link
G Tspo translocator protein multiple interactions EXP [Ketamine co-treated with Midazolam co-treated with Valproic Acid] inhibits the reaction [[Sarin co-treated with [Atropine co-treated with trimethylene-bis(4-hydroxyiminomethylpyridinium)]] results in increased expression of TSPO protein]; [Sarin co-treated with [Atropine co-treated with trimethylene-bis(4-hydroxyiminomethylpyridinium)]] results in increased expression of TSPO protein CTD PMID:33823148 NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of VCAM1 mRNA] CTD PMID:22245128 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
benzatropine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity ISO Benztropine results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression ISO Benztropine results in increased expression of ACOT2 protein CTD PMID:34122009 NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245
JBrowse link
G Actbl2 actin, beta-like 2 increases expression ISO Benztropine results in increased expression of ACTBL2 protein CTD PMID:34122009 NCBI chr 2:42,858,020...42,860,767
Ensembl chr 2:42,858,020...42,860,767
JBrowse link
G Actr1a actin related protein 1A multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of ACTR1A protein CTD PMID:34122009 NCBI chr 1:245,237,821...245,256,618
Ensembl chr 1:245,237,826...245,256,495
JBrowse link
G Actr3 actin related protein 3 decreases expression ISO Benztropine results in decreased expression of ACTR3 protein CTD PMID:34122009 NCBI chr13:36,800,739...36,843,837
Ensembl chr13:36,800,093...36,844,124
JBrowse link
G Adsl adenylosuccinate lyase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of ADSL protein CTD PMID:34122009 NCBI chr 7:112,479,256...112,503,439
Ensembl chr 7:112,479,271...112,503,760
JBrowse link
G Agps alkylglycerone phosphate synthase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of AGPS protein CTD PMID:34122009 NCBI chr 3:60,747,323...60,845,831
Ensembl chr 3:60,747,323...60,845,830
JBrowse link
G Ak1 adenylate kinase 1 decreases expression ISO Benztropine results in decreased expression of AK1 protein CTD PMID:34122009 NCBI chr 3:15,912,431...15,923,045
Ensembl chr 3:15,912,485...15,923,041
JBrowse link
G Anxa1 annexin A1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of ANXA1 protein CTD PMID:34122009 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Anxa5 annexin A5 decreases expression ISO Benztropine results in decreased expression of ANXA5 protein CTD PMID:34122009 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
JBrowse link
G Anxa6 annexin A6 decreases expression ISO Benztropine results in decreased expression of ANXA6 protein CTD PMID:34122009 NCBI chr10:39,101,395...39,156,483
Ensembl chr10:39,097,109...39,156,433
JBrowse link
G Anxa7 annexin A7 increases expression ISO Benztropine results in increased expression of ANXA7 protein CTD PMID:34122009 NCBI chr15:3,821,798...3,849,659
Ensembl chr15:3,821,845...3,849,385
JBrowse link
G Armt1 acidic residue methyltransferase 1 increases expression ISO Benztropine results in increased expression of ARMT1 protein CTD PMID:34122009 NCBI chr 1:40,894,558...40,918,302
Ensembl chr 1:40,894,550...40,918,302
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO Benztropine results in decreased expression of ASNS protein CTD PMID:34122009 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Asph aspartate-beta-hydroxylase increases expression ISO Benztropine results in increased expression of ASPH protein CTD PMID:34122009 NCBI chr 5:22,601,581...22,814,107
Ensembl chr 5:22,603,486...22,813,876
JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 increases expression ISO Benztropine results in increased expression of ATP2A3 protein CTD PMID:34122009 NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748
JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of ATP5F1C protein CTD PMID:34122009 NCBI chr17:68,423,927...68,446,169
Ensembl chr17:68,423,909...68,608,367
JBrowse link
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 decreases expression ISO Benztropine results in decreased expression of ATP6V1B2 protein CTD PMID:34122009 NCBI chr16:20,617,515...20,641,651
Ensembl chr16:20,617,518...20,641,745
JBrowse link
G Atxn10 ataxin 10 increases expression ISO Benztropine results in increased expression of ATXN10 protein CTD PMID:34122009 NCBI chr 7:116,441,768...116,565,093
Ensembl chr 7:116,441,613...116,565,087
JBrowse link
G Baz1b bromodomain adjacent to zinc finger domain, 1B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of BAZ1B protein CTD PMID:34122009 NCBI chr12:21,431,985...21,489,956
Ensembl chr12:21,431,985...21,490,426
JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member decreases expression ISO Benztropine results in decreased expression of BCAR1 protein CTD PMID:34122009 NCBI chr19:39,679,215...39,713,907
Ensembl chr19:39,679,204...39,713,907
JBrowse link
G Bltp1 bridge-like lipid transfer protein family member 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of BLTP1 protein CTD PMID:34122009 NCBI chr 2:119,708,114...119,924,697
Ensembl chr 2:119,708,209...119,924,695
JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO Benztropine results in increased expression of BMP6 mRNA CTD PMID:32816093 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G Brd2 bromodomain containing 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of BRD2 protein CTD PMID:34122009 NCBI chr20:4,727,078...4,735,389
Ensembl chr20:4,728,151...4,735,388
JBrowse link
G Bsg basigin (Ok blood group) decreases expression ISO Benztropine results in decreased expression of BSG protein CTD PMID:34122009 NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387
JBrowse link
G Cald1 caldesmon 1 decreases expression
multiple interactions
ISO Benztropine results in decreased expression of CALD1 protein
[Cuprizone co-treated with Benztropine] results in decreased expression of CALD1 protein
CTD PMID:34122009 NCBI chr 4:63,265,781...63,446,938
Ensembl chr 4:63,265,942...63,446,932
JBrowse link
G Calu calumenin decreases expression ISO Benztropine results in decreased expression of CALU protein CTD PMID:34122009 NCBI chr 4:57,949,086...57,976,589
Ensembl chr 4:57,948,997...57,976,593
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of CAMK2D protein CTD PMID:34122009 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178
JBrowse link
G Caprin1 cell cycle associated protein 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CAPRIN1 protein CTD PMID:34122009 NCBI chr 3:90,152,305...90,230,447
Ensembl chr 3:90,153,620...90,230,502
JBrowse link
G Casp8ap2 caspase 8 associated protein 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CASP8AP2 protein CTD PMID:34122009 NCBI chr 5:47,014,501...47,052,276
Ensembl chr 5:47,014,667...47,052,275
JBrowse link
G Cbx5 chromobox 5 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of CBX5 protein CTD PMID:34122009 NCBI chr 7:134,333,165...134,376,102
Ensembl chr 7:134,331,335...134,375,022
JBrowse link
G Ccar1 cell division cycle and apoptosis regulator 1 increases expression ISO Benztropine results in increased expression of CCAR1 protein CTD PMID:34122009 NCBI chr20:30,685,916...30,728,531
Ensembl chr20:30,685,916...30,728,526
JBrowse link
G Ccdc121 coiled-coil domain containing 121 increases expression ISO Benztropine results in increased expression of CCDC121 protein CTD PMID:34122009 NCBI chr 6:24,970,845...24,973,451
Ensembl chr 6:24,970,833...24,973,478
JBrowse link
G Cct6a chaperonin containing TCP1 subunit 6A multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CCT6A protein CTD PMID:34122009 NCBI chr12:26,872,736...26,883,125
Ensembl chr12:26,872,574...26,883,337
JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 decreases expression ISO Benztropine results in decreased expression of CCT7 protein CTD PMID:34122009 NCBI chr 4:117,989,232...118,006,478
Ensembl chr 4:117,989,232...118,006,580
JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CCT8 protein CTD PMID:34122009 NCBI chr11:26,710,370...26,722,079
Ensembl chr11:26,710,370...26,722,079
JBrowse link
G Cd276 Cd276 molecule decreases expression ISO Benztropine results in decreased expression of CD276 protein CTD PMID:34122009 NCBI chr 8:58,937,751...58,968,082
Ensembl chr 8:58,937,751...58,968,380
JBrowse link
G Cenpv centromere protein V increases expression ISO Benztropine results in increased expression of CENPV protein CTD PMID:34122009 NCBI chr10:47,214,479...47,228,552
Ensembl chr10:47,214,490...47,228,761
JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 decreases expression ISO Benztropine results in decreased expression of CHD4 protein CTD PMID:34122009 NCBI chr 4:157,898,503...157,931,632
Ensembl chr 4:157,899,391...157,931,541
JBrowse link
G Ckb creatine kinase B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of CKB protein CTD PMID:34122009 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase multiple interactions
decreases expression
ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CNP protein
Benztropine results in decreased expression of CNP protein
CTD PMID:34122009 NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720
JBrowse link
G Col14a1 collagen type XIV alpha 1 chain multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of COL14A1 protein CTD PMID:34122009 NCBI chr 7:86,722,093...86,937,215
Ensembl chr 7:86,722,094...86,937,214
JBrowse link
G Col5a2 collagen type V alpha 2 chain multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of COL5A2 protein CTD PMID:34122009 NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154
JBrowse link
G Cops4 COP9 signalosome subunit 4 decreases expression ISO Benztropine results in decreased expression of COPS4 protein CTD PMID:34122009 NCBI chr14:9,078,579...9,108,788
Ensembl chr14:9,078,576...9,108,887
JBrowse link
G Coro1b coronin 1B decreases expression ISO Benztropine results in decreased expression of CORO1B protein CTD PMID:34122009 NCBI chr 1:201,442,977...201,448,416
Ensembl chr 1:201,443,014...201,448,416
JBrowse link
G Coro7 coronin 7 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CORO7 protein CTD PMID:34122009 NCBI chr10:10,880,299...10,941,001
Ensembl chr10:10,885,196...10,941,001
JBrowse link
G Cpne3 copine 3 decreases expression ISO Benztropine results in decreased expression of CPNE3 protein CTD PMID:34122009 NCBI chr 5:33,014,658...33,063,934
Ensembl chr 5:33,016,307...33,063,934
JBrowse link
G Cpsf3 cleavage and polyadenylation specific factor 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CPSF3 protein CTD PMID:34122009 NCBI chr 6:40,836,121...40,864,129
Ensembl chr 6:40,836,097...40,864,128
JBrowse link
G Crtap cartilage associated protein increases expression ISO Benztropine results in increased expression of CRTAP protein CTD PMID:34122009 NCBI chr 8:114,047,929...114,067,636
Ensembl chr 8:114,047,933...114,067,631
JBrowse link
G Cryz crystallin zeta multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CRYZ protein CTD PMID:34122009 NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758
JBrowse link
G Csde1 cold shock domain containing E1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CSDE1 protein CTD PMID:34122009 NCBI chr 2:190,546,015...190,582,787
Ensembl chr 2:190,554,980...190,582,784
JBrowse link
G Cstf2 cleavage stimulation factor subunit 2 decreases expression ISO Benztropine results in decreased expression of CSTF2 protein CTD PMID:34122009 NCBI chr  X:97,253,559...97,279,476
Ensembl chr  X:97,253,586...97,279,476
JBrowse link
G Ctbp1 C-terminal binding protein 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CTBP1 protein CTD PMID:34122009 NCBI chr14:77,455,580...77,482,821
Ensembl chr14:77,455,696...77,482,821
JBrowse link
G Cul2 cullin 2 increases expression ISO Benztropine results in increased expression of CUL2 protein CTD PMID:34122009 NCBI chr17:54,169,093...54,210,197
Ensembl chr17:54,169,086...54,209,968
JBrowse link
G Cul4b cullin 4B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CUL4B protein CTD PMID:34122009 NCBI chr  X:117,287,481...117,326,688
Ensembl chr  X:117,287,484...117,326,688
JBrowse link
G Dars2 aspartyl-tRNA synthetase 2 (mitochondrial) multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of DARS2 protein CTD PMID:34122009 NCBI chr13:73,308,726...73,336,558
Ensembl chr13:73,308,726...73,336,934
JBrowse link
G Dazap1 DAZ associated protein 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of DAZAP1 protein CTD PMID:34122009 NCBI chr 7:9,423,673...9,448,116
Ensembl chr 7:9,424,178...9,538,818
JBrowse link
G Dctn2 dynactin subunit 2 increases expression ISO Benztropine results in increased expression of DCTN2 protein CTD PMID:34122009 NCBI chr 7:63,092,061...63,107,560
Ensembl chr 7:63,092,057...63,108,543
JBrowse link
G Ddx17 DEAD-box helicase 17 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of DDX17 protein CTD PMID:34122009 NCBI chr 7:111,091,127...111,109,353
Ensembl chr 7:111,089,445...111,109,193
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of DDX3X protein CTD PMID:34122009 NCBI chr  X:9,479,532...9,493,169
Ensembl chr  X:9,479,532...9,493,168
JBrowse link
G Dgcr6 DiGeorge syndrome critical region gene 6 decreases expression ISO Benztropine results in decreased expression of DGCR6 protein CTD PMID:34122009 NCBI chr11:82,927,725...82,932,823
Ensembl chr11:82,927,725...82,932,823
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase increases expression ISO Benztropine results in increased expression of DHCR24 protein CTD PMID:34122009 NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137
JBrowse link
G Dhx8 DEAH-box helicase 8 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of DHX8 protein CTD PMID:34122009 NCBI chr10:86,667,641...86,704,198
Ensembl chr10:86,667,834...86,705,137
JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase multiple interactions
increases expression
ISO [Cuprizone co-treated with Benztropine] results in decreased expression of DLAT protein
Benztropine results in increased expression of DLAT protein
CTD PMID:34122009 NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479
JBrowse link
G Dlg2 discs large MAGUK scaffold protein 2 increases expression ISO Benztropine results in increased expression of DLG2 protein CTD PMID:34122009 NCBI chr 1:144,451,653...146,503,949
Ensembl chr 1:144,451,472...146,499,475
JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 increases expression ISO Benztropine results in increased expression of DNAJB11 protein CTD PMID:34122009 NCBI chr11:78,151,750...78,168,259
Ensembl chr11:78,150,429...78,180,407
JBrowse link
G Dpp3 dipeptidylpeptidase 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of DPP3 protein CTD PMID:34122009 NCBI chr 1:202,204,683...202,228,501
Ensembl chr 1:202,204,693...202,228,541
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 decreases expression ISO Benztropine results in decreased expression of DPYSL2 protein CTD PMID:34122009 NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829
JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of DPYSL3 protein CTD PMID:34122009 NCBI chr18:35,374,427...35,480,228
Ensembl chr18:35,377,181...35,480,157
JBrowse link
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 decreases expression ISO Benztropine results in decreased expression of DYNC1LI1 protein CTD PMID:34122009 NCBI chr 8:114,376,649...114,410,297
Ensembl chr 8:114,376,662...114,410,934
JBrowse link
G Ebna1bp2 EBNA1 binding protein 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EBNA1BP2 protein CTD PMID:34122009 NCBI chr 5:132,148,164...132,152,730
Ensembl chr 5:132,148,143...132,153,267
JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EEF1G protein CTD PMID:34122009 NCBI chr 1:205,860,713...205,871,319
Ensembl chr 1:205,860,698...205,872,382
JBrowse link
G Eif2s3 eukaryotic translation initiation factor 2 subunit gamma increases expression ISO Benztropine results in increased expression of EIF2S3 protein CTD PMID:34122009 NCBI chr  X:58,916,513...58,939,923
Ensembl chr  X:58,917,490...58,940,686
JBrowse link
G Eif3b eukaryotic translation initiation factor 3, subunit B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EIF3B protein CTD PMID:34122009 NCBI chr12:14,196,403...14,220,865
Ensembl chr12:14,196,403...14,220,886
JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EIF3C protein CTD PMID:34122009 NCBI chr 1:181,134,604...181,152,489
Ensembl chr 1:181,134,604...181,152,493
JBrowse link
G Eif3h eukaryotic translation initiation factor 3, subunit H decreases expression ISO Benztropine results in decreased expression of EIF3H protein CTD PMID:34122009 NCBI chr 7:83,091,037...83,174,451
Ensembl chr 7:83,091,039...83,174,451
JBrowse link
G Eif3l eukaryotic translation initiation factor 3, subunit L increases expression
multiple interactions
ISO Benztropine results in increased expression of EIF3L protein
[Cuprizone co-treated with Benztropine] results in decreased expression of EIF3L protein
CTD PMID:34122009 NCBI chr 7:110,652,565...110,663,614
Ensembl chr 7:110,627,107...110,663,614
JBrowse link
G Eif5 eukaryotic translation initiation factor 5 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EIF5 protein CTD PMID:34122009 NCBI chr 6:130,589,162...130,597,656
Ensembl chr 6:130,589,143...130,597,656
JBrowse link
G Eif5b eukaryotic translation initiation factor 5B multiple interactions
increases expression
ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EIF5B protein
Benztropine results in increased expression of EIF5B protein
CTD PMID:34122009 NCBI chr 9:40,222,769...40,277,482
Ensembl chr 9:40,222,898...40,277,482
JBrowse link
G Eif6 eukaryotic translation initiation factor 6 decreases expression ISO Benztropine results in decreased expression of EIF6 protein CTD PMID:34122009 NCBI chr 3:144,325,038...144,331,396
Ensembl chr 3:144,325,036...144,331,401
JBrowse link
G Eno1 enolase 1 decreases expression ISO Benztropine results in decreased expression of ENO1 protein CTD PMID:34122009 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
JBrowse link
G Ephb3 Eph receptor B3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EPHB3 protein CTD PMID:34122009 NCBI chr11:79,840,668...79,859,345
Ensembl chr11:79,840,668...79,859,370
JBrowse link
G Epn1 Epsin 1 decreases expression ISO Benztropine results in decreased expression of EPN1 protein CTD PMID:34122009 NCBI chr 1:68,742,491...68,760,570
Ensembl chr 1:68,742,789...68,758,874
JBrowse link
G Eps8 EGFR pathway substrate 8, signaling adaptor decreases expression ISO Benztropine results in decreased expression of EPS8 protein CTD PMID:34122009 NCBI chr 4:170,388,378...170,486,873
Ensembl chr 4:170,388,378...170,486,873
JBrowse link
G Erh ERH, mRNA splicing and mitosis factor increases expression ISO Benztropine results in increased expression of ERH protein CTD PMID:34122009 NCBI chr 6:100,280,933...100,291,200
Ensembl chr 6:100,280,930...100,291,210
JBrowse link
G Erlin2 ER lipid raft associated 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of ERLIN2 protein CTD PMID:34122009 NCBI chr16:65,017,654...65,034,184
Ensembl chr16:65,018,532...65,033,671
JBrowse link
G Ewsr1 EWS RNA-binding protein 1 decreases expression ISO Benztropine results in decreased expression of EWSR1 protein CTD PMID:34122009 NCBI chr14:79,965,365...79,994,108
Ensembl chr14:79,965,368...79,994,544
JBrowse link
G Exosc9 exosome component 9 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EXOSC9 protein CTD PMID:34122009 NCBI chr 2:119,416,028...119,426,981
Ensembl chr 2:119,388,715...119,427,051
JBrowse link
G Ezr ezrin decreases expression ISO Benztropine results in decreased expression of EZR protein CTD PMID:34122009 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
JBrowse link
G Fabp3 fatty acid binding protein 3 increases expression ISO Benztropine results in increased expression of FABP3 protein CTD PMID:34122009 NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718
JBrowse link
G Fdps farnesyl diphosphate synthase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of FDPS protein CTD PMID:34122009 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
JBrowse link
G Flot2 flotillin 2 increases expression ISO Benztropine results in increased expression of FLOT2 protein CTD PMID:34122009 NCBI chr10:62,926,047...62,947,759
Ensembl chr10:62,920,665...62,947,756
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 decreases expression ISO Benztropine results in decreased expression of FLT1 protein CTD PMID:34122009 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
JBrowse link
G Fyco1 FYVE and coiled-coil domain autophagy adaptor 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of FYCO1 protein CTD PMID:34122009 NCBI chr 8:123,412,105...123,479,315
Ensembl chr 8:123,412,112...123,479,021
JBrowse link
G G3bp2 G3BP stress granule assembly factor 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of G3BP2 protein CTD PMID:34122009 NCBI chr14:15,932,403...16,020,555
Ensembl chr14:15,987,417...16,020,548
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases expression ISO Benztropine results in decreased expression of G6PD protein CTD PMID:34122009 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Galnt2 polypeptide N-acetylgalactosaminyltransferase 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of GALNT2 protein CTD PMID:34122009 NCBI chr19:52,213,226...52,324,816
Ensembl chr19:52,213,351...52,324,813
JBrowse link
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GART protein CTD PMID:34122009 NCBI chr11:30,864,896...30,891,125
Ensembl chr11:30,865,889...30,891,125
JBrowse link
G Gatad2b GATA zinc finger domain containing 2B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GATAD2B protein CTD PMID:34122009 NCBI chr 2:175,748,594...175,829,837
Ensembl chr 2:175,749,433...175,825,542
JBrowse link
G Gda guanine deaminase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of GDA protein CTD PMID:34122009 NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416
JBrowse link
G Gfpt1 glutamine fructose-6-phosphate transaminase 1 decreases expression ISO Benztropine results in decreased expression of GFPT1 protein CTD PMID:34122009 NCBI chr 4:119,496,691...119,546,472
Ensembl chr 4:119,496,714...119,546,471
JBrowse link
G Ggct gamma-glutamyl cyclotransferase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GGCT protein CTD PMID:34122009 NCBI chr 4:84,122,921...84,129,327
Ensembl chr 4:84,123,118...84,129,277
JBrowse link
G Glrx3 glutaredoxin 3 increases expression ISO Benztropine results in increased expression of GLRX3 protein CTD PMID:34122009 NCBI chr 1:192,241,707...192,272,012
Ensembl chr 1:192,241,701...192,272,010
JBrowse link
G Gls glutaminase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GLS protein CTD PMID:34122009 NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900
JBrowse link
G Gna12 G protein subunit alpha 12 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GNA12 protein CTD PMID:34122009 NCBI chr12:13,805,580...13,886,255
Ensembl chr12:13,805,698...13,886,255
JBrowse link
G Golga4 golgin A4 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of GOLGA4 protein CTD PMID:34122009 NCBI chr 8:118,208,200...118,285,003 JBrowse link
G Golgb1 golgin B1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GOLGB1 protein CTD PMID:34122009 NCBI chr11:63,843,179...63,900,665
Ensembl chr11:63,843,986...63,900,770
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of GOT2 protein CTD PMID:34122009 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
JBrowse link
G Gpi glucose-6-phosphate isomerase increases expression ISO Benztropine results in increased expression of GPI protein CTD PMID:34122009 NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086
JBrowse link
G Gpkow G patch domain and KOW motifs multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GPKOW protein CTD PMID:34122009 NCBI chr  X:14,791,601...14,806,384
Ensembl chr  X:14,791,610...14,806,384
JBrowse link
G Gtf2e1 general transcription factor IIE subunit 1 decreases expression ISO Benztropine results in decreased expression of GTF2E1 protein CTD PMID:34122009 NCBI chr11:63,182,073...63,215,349
Ensembl chr11:63,182,349...63,213,942
JBrowse link
G Gtf2f1 general transcription factor IIF subunit 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GTF2F1 protein CTD PMID:34122009 NCBI chr 9:1,844,027...1,853,455
Ensembl chr 9:1,843,901...1,853,423
JBrowse link
G Gtpbp4 GTP binding protein 4 increases expression ISO Benztropine results in increased expression of GTPBP4 protein CTD PMID:34122009 NCBI chr17:61,308,033...61,328,184
Ensembl chr17:61,308,014...61,418,009
JBrowse link
G Gys1 glycogen synthase 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GYS1 protein CTD PMID:34122009 NCBI chr 1:95,915,443...95,935,292
Ensembl chr 1:95,915,443...95,935,292
JBrowse link
G H2ac20 H2A clustered histone 20 increases expression ISO Benztropine results in increased expression of H2AC20 protein CTD PMID:34122009 NCBI chr 2:183,779,879...183,780,357 JBrowse link
G H2aj H2A.J histone increases expression ISO Benztropine results in increased expression of H2AJ protein CTD PMID:34122009 NCBI chr 4:169,675,718...169,676,202
Ensembl chr 4:169,675,752...169,677,006
JBrowse link
G Hacd3 3-hydroxyacyl-CoA dehydratase 3 increases expression ISO Benztropine results in increased expression of HACD3 protein CTD PMID:34122009 NCBI chr 8:65,501,240...65,538,507
Ensembl chr 8:65,501,240...65,538,507
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta increases expression ISO Benztropine results in increased expression of HADHB protein CTD PMID:34122009 NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869
JBrowse link
G Hars1 histidyl-tRNA synthetase 1 increases expression ISO Benztropine results in increased expression of HARS1 protein CTD PMID:34122009 NCBI chr18:28,381,649...28,398,699
Ensembl chr18:28,381,655...28,398,740
JBrowse link
G Hat1 histone acetyltransferase 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of HAT1 protein CTD PMID:34122009 NCBI chr 3:56,217,344...56,265,021
Ensembl chr 3:56,217,342...56,275,517
JBrowse link
G Hcfc1 host cell factor C1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of HCFC1 protein CTD PMID:34122009 NCBI chr  X:151,687,779...151,712,688
Ensembl chr  X:151,687,779...151,712,638
JBrowse link
G Hmcn2 hemicentin 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of HMCN2 protein CTD PMID:34122009 NCBI chr 3:14,588,353...14,738,320
Ensembl chr 3:14,588,662...14,738,025
JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D decreases expression ISO Benztropine results in decreased expression of HNRNPD protein CTD PMID:34122009 NCBI chr14:9,615,375...9,638,975
Ensembl chr14:9,615,479...9,633,786
JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of HNRNPK protein CTD PMID:34122009 NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997
JBrowse link
G Hps3 HPS3, biogenesis of lysosomal organelles complex 2 subunit 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of HPS3 protein CTD PMID:34122009 NCBI chr 2:102,484,574...102,527,580
Ensembl chr 2:102,484,574...102,526,047
JBrowse link
G Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 increases expression ISO Benztropine results in increased expression of HSD17B12 protein CTD PMID:34122009 NCBI chr 3:79,990,048...80,113,556
Ensembl chr 3:79,990,056...80,113,617
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of HSD17B4 protein CTD PMID:34122009 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of HSP90B1 protein CTD PMID:34122009 NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression ISO Benztropine results in decreased expression of IDI1 protein CTD PMID:34122009 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
JBrowse link
G Il1a interleukin 1 alpha decreases expression ISO Benztropine results in decreased expression of IL1A mRNA CTD PMID:32816093 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta decreases expression ISO Benztropine results in decreased expression of IL1B mRNA CTD PMID:32816093 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il24 interleukin 24 increases expression ISO Benztropine results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487
JBrowse link
G Jam3 junctional adhesion molecule 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of JAM3 protein CTD PMID:34122009 NCBI chr 8:25,508,461...25,569,306
Ensembl chr 8:25,507,057...25,569,355
JBrowse link
G Jpt2 Jupiter microtubule associated homolog 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of JPT2 protein CTD PMID:34122009 NCBI chr10:13,963,135...13,983,212
Ensembl chr10:13,963,137...13,983,170
JBrowse link
G Kars1 lysyl-tRNA synthetase 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of KARS1 protein CTD PMID:34122009 NCBI chr19:39,957,846...39,976,837
Ensembl chr19:39,957,846...39,977,632
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Benztropine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Kctd12 potassium channel tetramerization domain containing 12 decreases expression ISO Benztropine results in decreased expression of KCTD12 protein CTD PMID:34122009 NCBI chr15:79,800,078...79,806,017
Ensembl chr15:79,801,191...79,806,282
JBrowse link
G Khdrbs1 KH RNA binding domain containing, signal transduction associated 1 decreases expression ISO Benztropine results in decreased expression of KHDRBS1 protein CTD PMID:34122009 NCBI chr 5:142,051,844...142,089,175
Ensembl chr 5:142,063,570...142,089,180
JBrowse link
G Kif5c kinesin family member 5C decreases expression ISO Benztropine results in decreased expression of KIF5C protein CTD PMID:34122009 NCBI chr 3:34,032,082...34,185,597
Ensembl chr 3:34,032,105...34,182,413
JBrowse link
G Klhdc2 kelch domain containing 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of KLHDC2 protein CTD PMID:34122009 NCBI chr 6:87,777,183...87,791,609
Ensembl chr 6:87,777,183...87,804,187
JBrowse link
G Klhl41 kelch-like family member 41 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of KLHL41 protein CTD PMID:34122009 NCBI chr 3:54,434,291...54,447,415
Ensembl chr 3:54,434,234...54,449,222
JBrowse link
G Kpna4 karyopherin subunit alpha 4 increases expression ISO Benztropine results in increased expression of KPNA4 protein CTD PMID:34122009 NCBI chr 2:153,319,380...153,381,085
Ensembl chr 2:153,324,273...153,381,081
JBrowse link
G Ktn1 kinectin 1 multiple interactions
decreases expression
ISO [Cuprizone co-treated with Benztropine] results in increased expression of KTN1 protein
Benztropine results in decreased expression of KTN1 protein
CTD PMID:34122009 NCBI chr15:20,913,665...21,002,588
Ensembl chr15:20,914,642...21,002,578
JBrowse link
G Lactb2 lactamase, beta 2 increases expression ISO Benztropine results in increased expression of LACTB2 protein CTD PMID:34122009 NCBI chr 5:5,569,080...5,591,843
Ensembl chr 5:5,569,067...5,596,429
JBrowse link
G Lamb1 laminin subunit beta 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of LAMB1 protein CTD PMID:34122009 NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585
JBrowse link
G Lamc1 laminin subunit gamma 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of LAMC1 protein CTD PMID:34122009 NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492
JBrowse link
G Lima1 LIM domain and actin binding 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of LIMA1 protein CTD PMID:34122009 NCBI chr 7:130,901,717...131,001,512
Ensembl chr 7:130,901,717...131,001,473
JBrowse link
G Lipa lipase A, lysosomal acid type increases expression ISO Benztropine results in increased expression of LIPA protein CTD PMID:34122009 NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633
JBrowse link
G Lmod2 leiomodin 2 increases expression ISO Benztropine results in increased expression of LMOD2 protein CTD PMID:34122009 NCBI chr 4:53,067,428...53,075,124
Ensembl chr 4:53,067,428...53,075,120
JBrowse link
G Lss lanosterol synthase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of LSS protein CTD PMID:34122009 NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762
JBrowse link
G Lta4h leukotriene A4 hydrolase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of LTA4H protein CTD PMID:34122009 NCBI chr 7:27,969,796...28,001,600
Ensembl chr 7:27,969,789...28,001,600
JBrowse link
G Luc7l LUC7-like multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of LUC7L protein CTD PMID:34122009 NCBI chr10:15,273,340...15,307,131
Ensembl chr10:15,273,348...15,303,112
JBrowse link
G Magea9 MAGE family member A9 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of MAGEA9 protein CTD PMID:34122009 NCBI chr  X:142,619,282...142,624,654
Ensembl chr  X:142,619,395...142,624,653
JBrowse link
G Maged2 MAGE family member D2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of MAGED2 protein CTD PMID:34122009 NCBI chr  X:19,733,593...19,741,769
Ensembl chr  X:19,733,597...19,740,477
JBrowse link
G Map1s microtubule-associated protein 1S increases expression ISO Benztropine results in increased expression of MAP1S protein CTD PMID:34122009 NCBI chr16:18,516,759...18,527,777
Ensembl chr16:18,517,574...18,527,988
JBrowse link
G Map4 microtubule-associated protein 4 decreases expression ISO Benztropine results in decreased expression of MAP4 protein CTD PMID:34122009 NCBI chr 8:109,925,233...110,064,370
Ensembl chr 8:109,925,575...110,064,362
JBrowse link
G Mapre1 microtubule-associated protein, RP/EB family, member 1 decreases expression ISO Benztropine results in decreased expression of MAPRE1 protein CTD PMID:34122009 NCBI chr 3:142,218,846...142,246,990
Ensembl chr 3:142,212,955...142,246,983
JBrowse link
G Marcksl1 MARCKS-like 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of MARCKSL1 protein CTD PMID:34122009 NCBI chr 5:141,851,491...141,853,814
Ensembl chr 5:141,850,110...141,853,817
JBrowse link
G Mat2b methionine adenosyltransferase 2 non-catalytic beta subunit multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of MAT2B protein CTD PMID:34122009 NCBI chr10:25,106,928...25,122,982
Ensembl chr10:25,106,930...25,122,777
JBrowse link
G Mboat7 membrane bound O-acyltransferase domain containing 7 decreases expression ISO Benztropine results in decreased expression of MBOAT7 protein CTD PMID:34122009 NCBI chr 1:65,525,206...65,539,538
Ensembl chr 1:65,525,213...65,539,538
JBrowse link
G Mdh1 malate dehydrogenase 1 decreases expression ISO Benztropine results in decreased expression of MDH1 protein CTD PMID:34122009 NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase increases expression ISO Benztropine results in increased expression of MET mRNA CTD PMID:32816093 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
JBrowse link
G Metap2 methionyl aminopeptidase 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of METAP2 protein CTD PMID:34122009 NCBI chr 7:28,412,429...28,440,458
Ensembl chr 7:28,411,608...28,440,434
JBrowse link
G Mif macrophage migration inhibitory factor increases expression ISO Benztropine results in increased expression of MIF protein CTD PMID:34122009 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
JBrowse link
G Mtdh metadherin multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of MTDH protein CTD PMID:34122009 NCBI chr 7:65,306,464...65,365,647
Ensembl chr 7:65,306,400...65,364,413
JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of MTHFD1L protein CTD PMID:34122009 NCBI chr 1:40,443,926...40,632,911
Ensembl chr 1:40,444,008...40,632,905
JBrowse link
G Myh3 myosin heavy chain 3 increases expression ISO Benztropine results in increased expression of MYH3 protein CTD PMID:34122009 NCBI chr10:51,770,177...51,793,994
Ensembl chr10:51,770,177...51,793,992
JBrowse link
G Nat10 N-acetyltransferase 10 decreases expression ISO Benztropine results in decreased expression of NAT10 protein CTD PMID:34122009 NCBI chr 3:90,111,643...90,149,891
Ensembl chr 3:90,111,645...90,149,927
JBrowse link
G Ncbp1 nuclear cap binding protein subunit 1 decreases expression ISO Benztropine results in decreased expression of NCBP1 protein CTD PMID:34122009 NCBI chr 5:60,416,023...60,449,004
Ensembl chr 5:60,415,982...60,449,089
JBrowse link
G Nectin2 nectin cell adhesion molecule 2 decreases expression ISO Benztropine results in decreased expression of NECTIN2 protein CTD PMID:34122009 NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360
JBrowse link
G Nnmt nicotinamide N-methyltransferase increases expression ISO Benztropine results in increased expression of NNMT protein CTD PMID:34122009 NCBI chr 8:48,928,663...48,947,734
Ensembl chr 8:48,933,598...48,946,655
JBrowse link
G Noc2l NOC2-like nucleolar associated transcriptional repressor increases expression ISO Benztropine results in increased expression of NOC2L protein CTD PMID:34122009 NCBI chr 5:166,820,150...166,831,949
Ensembl chr 5:166,820,161...166,831,949
JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase decreases expression ISO Benztropine results in decreased expression of NSF protein CTD PMID:34122009 NCBI chr10:88,727,912...88,857,375
Ensembl chr10:88,727,912...88,857,386
JBrowse link
G Nsfl1c NSFL1 cofactor decreases expression ISO Benztropine results in decreased expression of NSFL1C protein CTD PMID:34122009 NCBI chr 3:139,978,306...140,002,876
Ensembl chr 3:139,978,301...140,002,870
JBrowse link
G Numa1 nuclear mitotic apparatus protein 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of NUMA1 protein CTD PMID:34122009 NCBI chr 1:156,297,907...156,372,855
Ensembl chr 1:156,326,259...156,372,855
JBrowse link
G Nup153 nucleoporin 153 increases expression ISO Benztropine results in increased expression of NUP153 protein CTD PMID:34122009 NCBI chr17:17,972,217...18,024,876
Ensembl chr17:17,972,217...18,024,876
JBrowse link
G Nup50 nucleoporin 50 increases expression ISO Benztropine results in increased expression of NUP50 protein CTD PMID:34122009 NCBI chr 7:116,047,960...116,065,231
Ensembl chr 7:116,048,021...116,066,905
JBrowse link
G Nup54 nucleoporin 54 decreases expression ISO Benztropine results in decreased expression of NUP54 protein CTD PMID:34122009 NCBI chr14:15,617,630...15,636,029
Ensembl chr14:15,617,679...15,636,028
JBrowse link
G Nup93 nucleoporin 93 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of NUP93 protein CTD PMID:34122009 NCBI chr19:10,684,214...10,788,009
Ensembl chr19:10,682,075...10,788,026
JBrowse link
G Nxf1 nuclear RNA export factor 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of NXF1 protein CTD PMID:34122009 NCBI chr 1:205,655,442...205,668,637
Ensembl chr 1:205,655,375...205,668,636
JBrowse link
G Oat ornithine aminotransferase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of OAT protein CTD PMID:34122009 NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
JBrowse link
G Ogdh oxoglutarate dehydrogenase decreases expression ISO Benztropine results in decreased expression of OGDH protein CTD PMID:34122009 NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479
JBrowse link
G Ola1 Obg-like ATPase 1 increases expression ISO Benztropine results in increased expression of OLA1 protein CTD PMID:34122009 NCBI chr 3:57,966,896...58,085,955
Ensembl chr 3:57,966,896...58,084,480
JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta decreases expression ISO Benztropine results in decreased expression of P4HB protein CTD PMID:34122009 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
JBrowse link
G Pa2g4 proliferation-associated 2G4 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PA2G4 protein CTD PMID:34122009 NCBI chr 7:984,795...992,264
Ensembl chr 7:983,971...992,331
JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PAFAH1B1 protein CTD PMID:34122009 NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808
JBrowse link
G Pag1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 decreases expression ISO Benztropine results in decreased expression of PAG1 protein CTD PMID:34122009 NCBI chr 2:91,935,378...92,076,937
Ensembl chr 2:92,057,216...92,069,849
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
decreases expression
ISO [Cuprizone co-treated with Benztropine] results in increased expression of PARP1 protein
Benztropine results in decreased expression of PARP1 protein
CTD PMID:34122009 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pc pyruvate carboxylase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of PC protein CTD PMID:34122009 NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380
JBrowse link
G Pcbp1 poly(rC) binding protein 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PCBP1 protein CTD PMID:34122009 NCBI chr 4:118,972,698...118,974,705
Ensembl chr 4:118,972,661...118,976,500
JBrowse link
G Pcbp2 poly(rC) binding protein 2 decreases expression ISO Benztropine results in decreased expression of PCBP2 protein CTD PMID:34122009 NCBI chr 7:133,605,375...133,631,312
Ensembl chr 7:133,605,573...133,629,863
JBrowse link
G Pcdhga2 protocadherin gamma subfamily A, 2 decreases expression ISO Benztropine results in decreased expression of PCDHGA2 protein CTD PMID:34122009 NCBI chr18:29,493,954...29,667,865
Ensembl chr18:29,493,954...29,667,868
JBrowse link
G Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 decreases expression ISO Benztropine results in decreased expression of PCMT1 protein CTD PMID:34122009 NCBI chr 1:2,111,756...2,160,354
Ensembl chr 1:2,111,763...2,159,201
JBrowse link
G Pcnp PEST proteolytic signal containing nuclear protein increases expression ISO Benztropine results in increased expression of PCNP protein CTD PMID:34122009 NCBI chr11:44,592,766...44,607,372
Ensembl chr11:44,592,742...44,607,348
JBrowse link
G Pdcl3 phosducin-like 3 decreases expression ISO Benztropine results in decreased expression of PDCL3 protein CTD PMID:34122009 NCBI chr 9:41,234,322...41,243,769
Ensembl chr 9:41,234,234...41,243,735
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 decreases expression ISO Benztropine results in decreased expression of PDIA3 protein CTD PMID:34122009 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PDIA6 protein CTD PMID:34122009 NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613
JBrowse link
G Pdlim5 PDZ and LIM domain 5 decreases expression ISO Benztropine results in decreased expression of PDLIM5 protein CTD PMID:34122009 NCBI chr 2:230,952,251...231,120,329
Ensembl chr 2:230,952,248...231,120,275
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 decreases expression ISO Benztropine results in decreased expression of PEBP1 protein CTD PMID:34122009 NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862
JBrowse link
G Pfn1 profilin 1 increases expression ISO Benztropine results in increased expression of PFN1 protein CTD PMID:34122009 NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631
JBrowse link
G Pgk1 phosphoglycerate kinase 1 decreases expression ISO Benztropine results in decreased expression of PGK1 protein CTD PMID:34122009 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418
JBrowse link
G Pgm3 phosphoglucomutase 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PGM3 protein CTD PMID:34122009 NCBI chr 8:87,518,317...87,536,021
Ensembl chr 8:87,517,701...87,536,022
JBrowse link
G Phf14 PHD finger protein 14 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PHF14 protein CTD PMID:34122009 NCBI chr 4:40,009,691...40,195,877
Ensembl chr 4:40,009,264...40,195,885
JBrowse link
G Phgdh phosphoglycerate dehydrogenase decreases expression ISO Benztropine results in decreased expression of PHGDH protein CTD PMID:34122009 NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944
JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 increases expression ISO Benztropine results in increased expression of PID1 mRNA CTD PMID:32816093 NCBI chr 9:85,284,335...85,503,035
Ensembl chr 9:85,284,335...85,503,044
JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PIN1 protein CTD PMID:34122009 NCBI chr 8:19,189,408...19,200,785
Ensembl chr 8:19,189,373...19,200,785
JBrowse link
G Pmpca peptidase, mitochondrial processing subunit alpha increases expression ISO Benztropine results in increased expression of PMPCA protein CTD PMID:34122009 NCBI chr 3:9,207,731...9,216,846
Ensembl chr 3:9,207,717...9,216,844
JBrowse link
G Pnma1 PNMA family member 1 increases expression ISO Benztropine results in increased expression of PNMA1 protein CTD PMID:34122009 NCBI chr 6:103,782,244...103,784,029
Ensembl chr 6:103,773,889...103,784,567
JBrowse link
G Pnma8a PNMA family member 8A multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PNMA8A protein CTD PMID:34122009 NCBI chr 1:77,629,272...77,643,156
Ensembl chr 1:77,639,423...77,642,082
JBrowse link
G Pon3 paraoxonase 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PON3 protein CTD PMID:34122009 NCBI chr 4:33,356,983...33,383,681
Ensembl chr 4:33,349,168...33,383,855
JBrowse link
G Ppa1 inorganic pyrophosphatase 1 multiple interactions
increases expression
ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PPA1 protein
Benztropine results in increased expression of PPA1 protein
CTD PMID:34122009 NCBI chr20:29,590,733...29,617,711
Ensembl chr20:29,590,707...29,619,215
JBrowse link
G Ppm1f protein phosphatase, Mg2+/Mn2+ dependent, 1F decreases expression ISO Benztropine results in decreased expression of PPM1F protein CTD PMID:34122009 NCBI chr11:84,064,422...84,094,410
Ensembl chr11:84,064,420...84,094,340
JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of PPP1R12A protein CTD PMID:34122009 NCBI chr 7:43,482,808...43,593,689
Ensembl chr 7:43,482,803...43,593,425
JBrowse link
G Ppp1r14b protein phosphatase 1, regulatory (inhibitor) subunit 14B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PPP1R14B protein CTD PMID:34122009 NCBI chr 1:204,165,210...204,167,320
Ensembl chr 1:204,163,299...204,167,319
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha increases expression ISO Benztropine results in increased expression of PPP3CA protein CTD PMID:34122009 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PRKAR2A protein CTD PMID:34122009 NCBI chr 8:109,393,189...109,458,832
Ensembl chr 8:109,395,833...109,455,628
JBrowse link
G Prkcsh PRKCSH beta subunit of glucosidase II multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of PRKCSH protein CTD PMID:34122009 NCBI chr 8:20,534,787...20,546,493
Ensembl chr 8:20,534,880...20,546,492
JBrowse link
G Prmt1 protein arginine methyltransferase 1 decreases expression ISO Benztropine results in decreased expression of PRMT1 protein CTD PMID:34122009 NCBI chr 1:95,458,853...95,468,176
Ensembl chr 1:95,458,850...95,468,345
JBrowse link
G Prpf6 pre-mRNA processing factor 6 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PRPF6 protein CTD PMID:34122009 NCBI chr 3:168,706,952...168,771,191
Ensembl chr 3:168,704,299...168,774,991
JBrowse link
G Psma1 proteasome 20S subunit alpha 1 decreases expression ISO Benztropine results in decreased expression of PSMA1 protein CTD PMID:34122009 NCBI chr 1:168,442,421...168,453,440
Ensembl chr 1:168,440,936...168,453,472
JBrowse link
G Psmb7 proteasome 20S subunit beta 7 decreases expression ISO Benztropine results in decreased expression of PSMB7 protein CTD PMID:34122009 NCBI chr 3:22,357,777...22,417,748
Ensembl chr 3:22,354,698...22,417,937
JBrowse link
G Psmc1 proteasome 26S subunit, ATPase 1 decreases expression ISO Benztropine results in decreased expression of PSMC1 protein CTD PMID:34122009 NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123
JBrowse link
G Psmc3 proteasome 26S subunit, ATPase 3 increases expression ISO Benztropine results in increased expression of PSMC3 protein CTD PMID:34122009 NCBI chr 3:77,031,825...77,037,207
Ensembl chr 3:77,031,825...77,043,358
JBrowse link
G Psmd7 proteasome 26S subunit, non-ATPase 7 increases expression ISO Benztropine results in increased expression of PSMD7 protein CTD PMID:34122009 NCBI chr19:35,494,317...35,501,605
Ensembl chr19:35,494,316...35,501,588
JBrowse link
G Ptcd3 Pentatricopeptide repeat domain 3 increases expression
multiple interactions
ISO Benztropine results in increased expression of PTCD3 protein
[Cuprizone co-treated with Benztropine] results in decreased expression of PTCD3 protein
CTD PMID:34122009 NCBI chr 4:103,922,440...103,957,445
Ensembl chr 4:103,920,566...103,957,538
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Benztropine results in decreased expression of PTGS2 mRNA CTD PMID:32816093 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptk7 protein tyrosine kinase 7 decreases expression ISO Benztropine results in decreased expression of PTK7 protein CTD PMID:34122009 NCBI chr 9:14,352,155...14,418,473
Ensembl chr 9:14,351,202...14,418,494
JBrowse link
G Puf60 poly-U binding splicing factor 60 decreases expression ISO Benztropine results in decreased expression of PUF60 protein CTD PMID:34122009 NCBI chr 7:107,782,799...107,793,759
Ensembl chr 7:107,782,770...107,794,531
JBrowse link
G Pwp2 PWP2, small subunit processome component increases expression ISO Benztropine results in increased expression of PWP2 protein CTD PMID:34122009 NCBI chr20:10,499,332...10,512,965
Ensembl chr20:10,499,363...10,513,640
JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 increases expression ISO Benztropine results in increased expression of PYCR1 protein CTD PMID:34122009 NCBI chr10:105,917,732...105,922,658
Ensembl chr10:105,917,680...105,922,549
JBrowse link
G Qdpr quinoid dihydropteridine reductase decreases expression ISO Benztropine results in decreased expression of QDPR protein CTD PMID:34122009 NCBI chr14:65,670,251...65,683,853
Ensembl chr14:65,670,131...65,683,854
JBrowse link
G Rack1 receptor for activated C kinase 1 decreases expression ISO Benztropine results in decreased expression of RACK1 protein CTD PMID:34122009 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975
JBrowse link
G Rbm15 RNA binding motif protein 15 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of RBM15 protein CTD PMID:34122009 NCBI chr 2:194,945,974...194,954,498
Ensembl chr 2:194,945,974...194,954,703
JBrowse link
G Ric8a RIC8 guanine nucleotide exchange factor A multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of RIC8A protein CTD PMID:34122009 NCBI chr 1:195,935,162...195,941,469
Ensembl chr 1:195,935,349...195,941,467
JBrowse link
G Rpl10a ribosomal protein L10A multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of RPL10A protein CTD PMID:34122009 NCBI chr20:6,388,800...6,391,358
Ensembl chr20:6,385,823...6,391,357
JBrowse link
G Rpl19 ribosomal protein L19 increases expression ISO Benztropine results in increased expression of RPL19 protein CTD PMID:34122009 NCBI chr10:83,022,503...83,026,030
Ensembl chr10:83,019,257...83,052,112
JBrowse link
G Rpl24 ribosomal protein L24 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of RPL24 protein CTD PMID:34122009 NCBI chr11:44,653,937...44,659,346
Ensembl chr11:44,653,937...44,659,370
JBrowse link
G Rpl30 ribosomal protein L30 increases expression ISO Benztropine results in increased expression of RPL30 protein CTD PMID:34122009 NCBI chr 7:65,648,266...65,651,401
Ensembl chr 7:65,645,991...65,651,363
Ensembl chr10:65,645,991...65,651,363
Ensembl chr10:65,645,991...65,651,363
JBrowse link
G Rpl7a ribosomal protein L7A decreases expression ISO Benztropine results in decreased expression of RPL7A protein CTD PMID:34122009 NCBI chr 3:10,239,026...10,241,703
Ensembl chr 3:10,239,001...10,241,716
JBrowse link
G Rplp1 ribosomal protein lateral stalk subunit P1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of RPLP1 protein CTD PMID:34122009 NCBI chr 8:62,394,008...62,395,341
Ensembl chr 8:62,393,177...62,395,339
JBrowse link
G Rps12 ribosomal protein S12 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of RPS12 protein CTD PMID:34122009 NCBI chr 1:21,680,854...21,683,010
Ensembl chr 1:21,680,852...21,683,014
JBrowse link
G Rps18 ribosomal protein S18 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of RPS18 protein CTD PMID:34122009 NCBI chr20:4,931,427...4,935,538
Ensembl chr10:101,204,500...101,205,146
Ensembl chr20:101,204,500...101,205,146
JBrowse link
G Rps27 ribosomal protein S27 increases expression ISO Benztropine results in increased expression of RPS27 protein CTD PMID:34122009 NCBI chr 2:175,665,858...175,666,963
Ensembl chr 2:175,665,853...175,666,964
JBrowse link
G Rps27a ribosomal protein S27a increases expression ISO Benztropine results in increased expression of RPS27A protein CTD PMID:34122009 NCBI chr14:103,285,734...103,288,011
Ensembl chr14:103,285,734...103,288,011
Ensembl chr 5:103,285,734...103,288,011
JBrowse link
G Rps3 ribosomal protein S3 decreases expression ISO Benztropine results in decreased expression of RPS3 protein CTD PMID:34122009 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680
JBrowse link
G Ruvbl2 RuvB-like AAA ATPase 2 increases expression ISO Benztropine results in increased expression of RUVBL2 protein CTD PMID:34122009 NCBI chr 1:95,902,014...95,915,247
Ensembl chr 1:95,901,701...95,915,342
JBrowse link
G Sae1 SUMO1 activating enzyme subunit 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SAE1 protein CTD PMID:34122009 NCBI chr 1:77,030,961...77,086,937
Ensembl chr 1:77,030,965...77,086,986
JBrowse link
G Sars1 seryl-tRNA synthetase 1 decreases expression ISO Benztropine results in decreased expression of SARS1 protein CTD PMID:34122009 NCBI chr 2:196,065,543...196,081,240
Ensembl chr 2:196,065,430...196,081,277
JBrowse link
G Satb2 SATB homeobox 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of SATB2 protein CTD PMID:34122009 NCBI chr 9:58,348,027...58,534,256
Ensembl chr 9:58,350,246...58,530,707
JBrowse link
G Sccpdh saccharopine dehydrogenase (putative) decreases expression ISO Benztropine results in decreased expression of SCCPDH protein CTD PMID:34122009 NCBI chr13:91,400,120...91,421,875
Ensembl chr13:91,400,190...91,422,222
JBrowse link
G Sdcbp syndecan binding protein decreases expression ISO Benztropine results in decreased expression of SDCBP protein CTD PMID:34122009 NCBI chr 5:19,473,499...19,517,188
Ensembl chr 5:19,489,961...19,527,572
JBrowse link
G Sec23a Sec23 homolog A, COPII coat complex component multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of SEC23A protein CTD PMID:34122009 NCBI chr 6:76,658,793...76,706,125
Ensembl chr 6:76,658,427...76,706,035
JBrowse link
G Sec61b SEC61 translocon subunit beta increases expression ISO Benztropine results in increased expression of SEC61B protein CTD PMID:34122009 NCBI chr 5:61,773,594...61,781,804
Ensembl chr 5:61,773,594...61,781,804
JBrowse link
G Sec63 SEC63 homolog, protein translocation regulator increases expression ISO Benztropine results in increased expression of SEC63 protein CTD PMID:34122009 NCBI chr20:46,245,101...46,314,055
Ensembl chr20:46,245,101...46,314,055
JBrowse link
G Serbp1 Serpine1 mRNA binding protein 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SERBP1 protein CTD PMID:34122009 NCBI chr 4:96,401,587...96,421,816
Ensembl chr 4:96,401,477...96,421,813
JBrowse link
G Serpinb3a serpin family B member 3A increases expression ISO Benztropine results in increased expression of SERPINB4 protein CTD PMID:34122009 NCBI chr13:23,241,303...23,246,328
Ensembl chr13:23,236,972...23,246,985
JBrowse link
G Sf1 splicing factor 1 decreases expression ISO Benztropine results in decreased expression of SF1 protein CTD PMID:34122009 NCBI chr 1:203,670,016...203,683,432
Ensembl chr 1:203,670,018...203,684,330
JBrowse link
G Sf3b3 splicing factor 3b, subunit 3 decreases expression ISO Benztropine results in decreased expression of SF3B3 protein CTD PMID:34122009 NCBI chr19:38,782,749...38,820,271
Ensembl chr19:38,783,040...38,820,245
JBrowse link
G Sgca sarcoglycan, alpha decreases expression ISO Benztropine results in decreased expression of SGCA protein CTD PMID:34122009 NCBI chr10:79,904,698...79,922,808
Ensembl chr10:79,908,738...79,922,813
JBrowse link
G Sh3pxd2b SH3 and PX domains 2B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SH3PXD2B protein CTD PMID:34122009 NCBI chr10:16,918,611...17,027,499
Ensembl chr10:16,918,679...17,005,170
JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SHMT1 protein CTD PMID:34122009 NCBI chr10:45,468,698...45,490,833
Ensembl chr10:45,468,700...45,497,820
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Benztropine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Slc25a6 solute carrier family 25 member 6 increases expression ISO Benztropine results in increased expression of SLC25A6 protein CTD PMID:34122009 NCBI chr18:68,571,222...68,572,461
Ensembl chr18:68,571,300...68,572,199
JBrowse link
G Slc2a1 solute carrier family 2 member 1 decreases expression ISO Benztropine results in decreased expression of SLC2A1 protein CTD PMID:34122009 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
G Slc38a2 solute carrier family 38, member 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of SLC38A2 protein CTD PMID:34122009 NCBI chr 7:127,851,267...127,863,482
Ensembl chr 7:127,851,267...127,863,436
JBrowse link
G Slc3a2 solute carrier family 3 member 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of SLC3A2 protein CTD PMID:34122009 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions ISO Benztropine inhibits the reaction [SLC6A3 protein results in increased uptake of Dopamine] CTD PMID:17250655 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Benztropine results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453
JBrowse link
G Smarcb1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 decreases expression ISO Benztropine results in decreased expression of SMARCB1 protein CTD PMID:34122009 NCBI chr20:12,741,164...12,763,616
Ensembl chr20:12,741,477...12,763,620
JBrowse link
G Smc3 structural maintenance of chromosomes 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SMC3 protein CTD PMID:34122009 NCBI chr 1:252,601,422...252,644,522
Ensembl chr 1:252,601,753...252,644,522
JBrowse link
G Smu1 SMU1, DNA replication regulator and spliceosomal factor multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SMU1 protein CTD PMID:34122009 NCBI chr 5:55,856,691...55,875,262
Ensembl chr 5:55,856,246...55,875,300
JBrowse link
G Snrnp200 small nuclear ribonucleoprotein U5 subunit 200 multiple interactions
increases expression
ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SNRNP200 protein
Benztropine results in increased expression of SNRNP200 protein
CTD PMID:34122009 NCBI chr 3:114,428,854...114,458,194
Ensembl chr 3:114,428,854...114,458,182
JBrowse link
G Snrpa small nuclear ribonucleoprotein polypeptide A increases expression ISO Benztropine results in increased expression of SNRPA protein CTD PMID:34122009 NCBI chr 1:82,481,770...82,490,540
Ensembl chr 1:82,481,770...82,490,538
JBrowse link
G Snrpd2 small nuclear ribonucleoprotein D2 polypeptide increases expression ISO Benztropine results in increased expression of SNRPD2 protein CTD PMID:34122009 NCBI chr 1:78,798,377...78,801,227
Ensembl chr 1:78,798,377...78,803,351
JBrowse link
G Srek1 splicing regulatory glutamic acid and lysine rich protein 1 decreases expression ISO Benztropine results in decreased expression of SREK1 protein CTD PMID:34122009 NCBI chr 2:34,849,548...34,885,120
Ensembl chr 2:34,852,458...34,884,972
JBrowse link
G Srsf5 serine and arginine rich splicing factor 5 increases expression ISO Benztropine results in increased expression of SRSF5 protein CTD PMID:34122009 NCBI chr 6:100,605,165...100,610,192
Ensembl chr 6:100,605,456...100,610,177
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of STAT3 protein CTD PMID:34122009 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Stim1 stromal interaction molecule 1 decreases expression ISO Benztropine results in decreased expression of STIM1 protein CTD PMID:34122009 NCBI chr 1:156,656,246...156,818,777
Ensembl chr 1:156,656,013...156,818,363
JBrowse link
G Stip1 stress-induced phosphoprotein 1 decreases expression ISO Benztropine results in decreased expression of STIP1 protein CTD PMID:34122009 NCBI chr 1:204,209,433...204,228,452
Ensembl chr 1:204,178,932...204,228,476
JBrowse link
G Strap serine/threonine kinase receptor associated protein decreases expression ISO Benztropine results in decreased expression of STRAP protein CTD PMID:34122009 NCBI chr 4:170,646,042...170,660,291
Ensembl chr 4:170,646,001...170,660,828
JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of STUB1 protein CTD PMID:34122009 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046
JBrowse link
G Suclg1 succinate-CoA ligase GDP/ADP-forming subunit alpha decreases expression ISO Benztropine results in decreased expression of SUCLG1 protein CTD PMID:34122009 NCBI chr 4:105,308,236...105,337,595
Ensembl chr 4:105,308,039...105,337,600
JBrowse link
G Sumo2 small ubiquitin-like modifier 2 decreases expression ISO Benztropine results in decreased expression of SUMO2 protein CTD PMID:34122009 NCBI chr10:100,771,941...100,784,503
Ensembl chr10:100,686,797...100,784,513
JBrowse link
G Sun1 Sad1 and UNC84 domain containing 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SUN1 protein CTD PMID:34122009 NCBI chr12:15,396,378...15,441,277
Ensembl chr12:15,396,381...15,441,571
JBrowse link
G Syncrip synaptotagmin binding, cytoplasmic RNA interacting protein decreases expression ISO Benztropine results in decreased expression of SYNCRIP protein CTD PMID:34122009 NCBI chr 8:89,402,487...89,435,517
Ensembl chr 8:89,402,866...89,435,515
JBrowse link
G Tagln2 transgelin 2 decreases expression ISO Benztropine results in decreased expression of TAGLN2 protein CTD PMID:34122009 NCBI chr13:84,966,980...84,973,973
Ensembl chr13:84,967,009...84,973,972
JBrowse link
G Tbcb tubulin folding cofactor B decreases expression ISO Benztropine results in decreased expression of TBCB protein CTD PMID:34122009 NCBI chr 1:85,477,639...85,483,488
Ensembl chr 1:85,477,640...85,483,488
JBrowse link
G Tcaf1 TRPM8 channel-associated factor 1 multiple interactions
decreases expression
ISO [Cuprizone co-treated with Benztropine] results in decreased expression of TCAF1 protein
Benztropine results in decreased expression of TCAF1 protein
CTD PMID:34122009 NCBI chr 4:71,589,674...71,639,274
Ensembl chr 4:71,591,200...71,613,309
JBrowse link
G Tgoln2 trans-golgi network protein 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of TGOLN2 protein CTD PMID:34122009 NCBI chr 4:104,663,356...104,671,208
Ensembl chr 4:104,663,353...104,671,164
JBrowse link
G Tln2 talin 2 decreases expression ISO Benztropine results in decreased expression of TLN2 protein CTD PMID:34122009 NCBI chr 8:67,830,920...68,252,240
Ensembl chr 8:67,834,326...68,252,219
JBrowse link
G Tmpo thymopoietin decreases expression ISO Benztropine results in decreased expression of TMPO protein CTD PMID:34122009 NCBI chr 7:25,642,752...25,667,756
Ensembl chr 7:25,586,725...25,667,727
JBrowse link
G Tnks1bp1 tankyrase 1 binding protein 1 multiple interactions
decreases expression
ISO [Cuprizone co-treated with Benztropine] results in decreased expression of TNKS1BP1 protein
Benztropine results in decreased expression of TNKS1BP1 protein
CTD PMID:34122009 NCBI chr 3:70,135,335...70,160,071
Ensembl chr 3:70,137,837...70,160,038
JBrowse link
G Tomm34 translocase of outer mitochondrial membrane 34 decreases expression
multiple interactions
ISO Benztropine results in decreased expression of TOMM34 protein
[Cuprizone co-treated with Benztropine] results in increased expression of TOMM34 protein
CTD PMID:34122009 NCBI chr 3:152,729,345...152,746,295
Ensembl chr 3:152,729,349...152,746,373
JBrowse link
G Top1mt DNA topoisomerase I mitochondrial increases expression ISO Benztropine results in increased expression of TOP1MT protein CTD PMID:34122009 NCBI chr 7:107,338,092...107,368,125
Ensembl chr 7:107,342,527...107,366,049
JBrowse link
G Tpm2 tropomyosin 2 decreases expression ISO Benztropine results in decreased expression of TPM2 protein CTD PMID:34122009 NCBI chr 5:57,770,919...57,780,278
Ensembl chr 5:57,770,864...57,779,992
JBrowse link
G Tpm3 tropomyosin 3 decreases expression ISO Benztropine results in decreased expression of TPM3 protein CTD PMID:34122009 NCBI chr 2:175,517,198...175,545,014
Ensembl chr 2:175,517,226...175,545,013
JBrowse link
G Tpr translocated promoter region, nuclear basket protein decreases expression ISO Benztropine results in decreased expression of TPR protein CTD PMID:34122009 NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496
JBrowse link
G Trim28 tripartite motif-containing 28 decreases expression
multiple interactions
ISO Benztropine results in decreased expression of TRIM28 protein
[Cuprizone co-treated with Benztropine] results in increased expression of TRIM28 protein
CTD PMID:34122009 NCBI chr 1:73,652,441...73,659,388
Ensembl chr 1:73,652,709...73,659,380
JBrowse link
G Tspan3 tetraspanin 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of TSPAN3 protein CTD PMID:34122009 NCBI chr 8:56,546,067...56,569,815
Ensembl chr 8:56,546,069...56,569,880
JBrowse link
G Ttc21a tetratricopeptide repeat domain 21A multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of TTC21A protein CTD PMID:34122009 NCBI chr 8:119,667,044...119,702,028
Ensembl chr 8:119,666,933...119,702,456
JBrowse link
G Ttyh2 tweety family member 2 increases expression ISO Benztropine results in increased expression of TTYH2 protein CTD PMID:34122009 NCBI chr10:99,709,063...99,753,449
Ensembl chr10:99,709,007...99,753,444
JBrowse link
G Ttyh3 tweety family member 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of TTYH3 protein CTD PMID:34122009 NCBI chr12:13,996,831...14,025,457
Ensembl chr12:13,997,045...14,025,459
JBrowse link
G Tubb5 tubulin, beta 5 class I increases expression ISO Benztropine results in increased expression of TUBB protein CTD PMID:34122009 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
JBrowse link
G Twf2 twinfilin actin-binding protein 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of TWF2 protein CTD PMID:34122009 NCBI chr 8:106,845,253...106,858,298
Ensembl chr 8:106,845,253...106,858,298
JBrowse link
G Txlna taxilin alpha decreases expression ISO Benztropine results in decreased expression of TXLNA protein CTD PMID:34122009 NCBI chr 5:141,969,337...141,985,054
Ensembl chr 5:141,969,346...141,984,583
JBrowse link
G Tyms thymidylate synthetase increases expression ISO Benztropine results in increased expression of TYMS protein CTD PMID:34122009 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
JBrowse link
G U2af2 U2 small nuclear RNA auxiliary factor 2 decreases expression ISO Benztropine results in decreased expression of U2AF2 protein CTD PMID:34122009 NCBI chr 1:68,760,911...68,779,730
Ensembl chr 1:68,760,924...68,778,492
JBrowse link
G Uba2 ubiquitin-like modifier activating enzyme 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of UBA2 protein CTD PMID:34122009 NCBI chr 1:86,775,239...86,802,685
Ensembl chr 1:86,775,244...86,802,682
JBrowse link
G Ubap2l ubiquitin associated protein 2-like decreases expression ISO Benztropine results in decreased expression of UBAP2L protein CTD PMID:34122009 NCBI chr 2:175,438,703...175,494,085
Ensembl chr 2:175,438,703...175,493,998
JBrowse link
G Ubc ubiquitin C increases expression ISO Benztropine results in increased expression of UBC protein CTD PMID:34122009 NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925
JBrowse link
G Ubqln2 ubiquilin 2 decreases expression ISO Benztropine results in decreased expression of UBQLN2 protein CTD PMID:34122009 NCBI chr  X:17,853,086...17,856,505
Ensembl chr  X:17,853,114...17,856,505
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of UCHL1 protein CTD PMID:34122009 NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590
JBrowse link
G Uchl3 ubiquitin C-terminal hydrolase L3 decreases expression ISO Benztropine results in decreased expression of UCHL3 protein CTD PMID:34122009 NCBI chr15:78,485,304...78,527,355
Ensembl chr15:78,485,315...78,527,355
Ensembl chr 3:78,485,315...78,527,355
JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase decreases expression ISO Benztropine results in decreased expression of UGDH protein CTD PMID:34122009 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354
JBrowse link
G Unc45b unc-45 myosin chaperone B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of UNC45B protein CTD PMID:34122009 NCBI chr10:67,845,464...67,873,143
Ensembl chr10:67,845,462...67,873,389
JBrowse link
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of UQCRC2 protein CTD PMID:34122009 NCBI chr 1:175,167,933...175,198,499
Ensembl chr 1:175,167,894...175,199,453
JBrowse link
G Uso1 USO1 vesicle transport factor decreases expression ISO Benztropine results in decreased expression of USO1 protein CTD PMID:34122009 NCBI chr14:15,866,638...15,932,185
Ensembl chr14:15,866,638...15,932,171
JBrowse link
G Usp10 ubiquitin specific peptidase 10 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of USP10 protein CTD PMID:34122009 NCBI chr19:47,972,858...48,014,900
Ensembl chr19:47,972,611...48,014,897
JBrowse link
G Usp14 ubiquitin specific peptidase 14 increases expression ISO Benztropine results in increased expression of USP14 protein CTD PMID:34122009 NCBI chr18:1,018,111...1,057,727
Ensembl chr18:1,019,400...1,057,519
JBrowse link
G Utp18 UTP18 small subunit processome component increases expression ISO Benztropine results in increased expression of UTP18 protein CTD PMID:34122009 NCBI chr10:78,811,879...78,839,338
Ensembl chr10:78,811,880...78,839,627
JBrowse link
G Vasp vasodilator-stimulated phosphoprotein decreases expression ISO Benztropine results in decreased expression of VASP protein CTD PMID:34122009 NCBI chr 1:78,910,009...78,925,791
Ensembl chr 1:78,910,011...78,925,061
JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of WARS1 protein CTD PMID:34122009 NCBI chr 6:127,776,088...127,807,273
Ensembl chr 6:127,776,090...127,807,269
JBrowse link
G Wdr12 WD repeat domain 12 decreases expression ISO Benztropine results in decreased expression of WDR12 protein CTD PMID:34122009 NCBI chr 9:61,475,498...61,502,762
Ensembl chr 9:61,475,517...61,502,469
JBrowse link
G Xirp2 xin actin-binding repeat containing 2 decreases expression ISO Benztropine results in decreased expression of XIRP2 protein CTD PMID:34122009 NCBI chr 3:52,126,213...52,213,094
Ensembl chr 3:51,870,092...52,213,091
JBrowse link
G Xpo7 exportin 7 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of XPO7 protein CTD PMID:34122009 NCBI chr15:45,742,053...45,828,050
Ensembl chr15:45,742,053...45,828,050
JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta increases expression ISO Benztropine results in increased expression of YWHAQ protein CTD PMID:34122009 NCBI chr 6:40,935,714...40,966,240
Ensembl chr 6:40,935,949...40,966,273
JBrowse link
G Zbtb42 zinc finger and BTB domain containing 42 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of ZBTB42 protein CTD PMID:34122009 NCBI chr 6:131,734,257...131,742,459
Ensembl chr 6:131,738,356...131,742,685
JBrowse link
G Zfr zinc finger RNA binding protein decreases expression ISO Benztropine results in decreased expression of ZFR protein CTD PMID:34122009 NCBI chr 2:61,137,611...61,200,322
Ensembl chr 2:61,137,611...61,200,322
JBrowse link
G Zkscan7 zinc finger with KRAB and SCAN domains 7 decreases expression ISO Benztropine results in decreased expression of ZKSCAN7 protein CTD PMID:34122009 NCBI chr 8:122,501,938...122,519,600
Ensembl chr 8:122,502,218...122,519,600
JBrowse link
dextromethorphan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation
ISO rostafuroxin inhibits the reaction [Dextromethorphan results in increased phosphorylation of AKT1 protein] CTD PMID:34740715 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
EXP Dizocilpine Maleate inhibits the reaction [Dextromethorphan results in increased expression of BAX protein]; traxoprodil mesylate inhibits the reaction [Dextromethorphan results in increased expression of BAX protein] CTD PMID:28916251 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
EXP traxoprodil mesylate inhibits the reaction [Dextromethorphan results in decreased expression of BCL2 protein] CTD PMID:28916251 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression
multiple interactions
EXP Dextromethorphan results in decreased expression of BCL2L1 protein
Dizocilpine Maleate inhibits the reaction [Dextromethorphan results in decreased expression of BCL2L1 protein]; traxoprodil mesylate inhibits the reaction [Dextromethorphan results in decreased expression of BCL2L1 protein]
CTD PMID:28916251 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
EXP Dizocilpine Maleate inhibits the reaction [Dextromethorphan results in increased cleavage of CASP3 protein]; traxoprodil mesylate inhibits the reaction [Dextromethorphan results in increased cleavage of CASP3 protein] CTD PMID:28916251 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression
increases secretion
ISO Dextromethorphan results in decreased expression of CCL2 protein
Dextromethorphan results in increased secretion of CCL2 protein
CTD PMID:19189960 PMID:32871113 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO Dextromethorphan results in decreased activity of CYP1A1 protein CTD PMID:18420780 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects metabolic processing ISO CYP1A2 protein affects the metabolism of Dextromethorphan CTD PMID:15199075 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Dextromethorphan results in decreased activity of CYP1B1 protein CTD PMID:18420780 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 decreases activity ISO Dextromethorphan results in decreased activity of CYP2A4 protein CTD PMID:18420780 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases activity ISO Dextromethorphan results in decreased activity of CYP2B10 protein CTD PMID:18420780 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 affects metabolic processing EXP CYP2C13 protein affects the metabolism of Dextromethorphan CTD PMID:15879494 NCBI chr 1:238,786,764...238,867,195
Ensembl chr 1:238,786,765...238,867,191
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 affects metabolic processing ISO CYP2C19 protein affects the metabolism of Dextromethorphan CTD PMID:15286053 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 decreases methylation
multiple interactions
increases metabolic processing
EXP CYP2D2 protein results in decreased methylation of Dextromethorphan
[CYP2D2 protein results in increased metabolism of Dextromethorphan] which results in increased chemical synthesis of Dextrorphan
CTD PMID:11911841 PMID:28438436 NCBI chr 7:113,935,138...113,939,209
Ensembl chr 7:113,935,138...113,939,209
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects metabolic processing
decreases methylation
increases metabolic processing
multiple interactions
decreases activity
increases response to substance
ISO
EXP
CYP2D6 polymorphism affects the metabolism of Dextromethorphan; CYP2D6 protein affects the metabolism of Dextromethorphan; CYP2D6 protein polymorphism affects the metabolism of Dextromethorphan
CYP2D6 protein results in decreased methylation of Dextromethorphan
CYP2D6 mRNA results in increased metabolism of Dextromethorphan; CYP2D6 protein results in increased metabolism of Dextromethorphan
[CYP2D22 protein results in increased metabolism of Dextromethorphan] which results in increased chemical synthesis of Dextrorphan; Ketoconazole inhibits the reaction [CYP2D22 protein results in increased metabolism of Dextromethorphan]
Dextromethorphan results in decreased activity of CYP2D6 protein
Cimetidine inhibits the reaction [CYP2D6 protein results in increased metabolism of Dextromethorphan]; ozagrel promotes the reaction [CYP2D6 protein results in increased metabolism of Dextromethorphan]
[5-bromotryptamine analog results in decreased activity of CYP2D6 protein] which results in decreased metabolism of Dextromethorphan; [5-chlorotryptamine analog results in decreased activity of CYP2D6 protein] which results in decreased metabolism of Dextromethorphan; [5-fluoro-alpha-methyltryptamine analog results in decreased activity of CYP2D6 protein] which results in decreased metabolism of Dextromethorphan; [5-fluoro-alpha-methyltryptamine results in decreased activity of CYP2D6 protein] which results in decreased metabolism of Dextromethorphan; [5-fluorotryptamine analog results in decreased activity of CYP2D6 protein] which results in decreased metabolism of Dextromethorphan; [5-methoxy-N,N-diisopropyltryptamine analog results in decreased activity of CYP2D6 protein] which results in decreased metabolism of Dextromethorphan; [5-methyltryptamine analog results in decreased activity of CYP2D6 protein] which results in decreased metabolism of Dextromethorphan; [7-methyltryptamine analog results in decreased activity of CYP2D6 protein] which results in decreased metabolism of Dextromethorphan; [CYP2D6 mRNA results in increased metabolism of Dextromethorphan] which results in increased chemical synthesis of Dextrorphan; [CYP2D6 protein results in increased metabolism of Dextromethorphan] which results in increased chemical synthesis of Dextrorphan; [Fluoxetine results in decreased activity of CYP2D6 protein] which results in decreased metabolism of Dextromethorphan; [indopan analog results in decreased activity of CYP2D6 protein] which results in decreased metabolism of Dextromethorphan; [indopan results in decreased activity of CYP2D6 protein] which results in decreased metabolism of Dextromethorphan; [Methoxydimethyltryptamines analog results in decreased activity of CYP2D6 protein] which results in decreased metabolism of Dextromethorphan; [N,N-diallyl-5-methoxytryptamine results in decreased activity of CYP2D6 protein] which results in decreased metabolism of Dextromethorphan; [N,N-diisopropyltryptamine analog results in decreased activity of CYP2D6 protein] which results in decreased metabolism of Dextromethorphan; [Paroxetine results in decreased activity of CYP2D6 protein] which results in decreased metabolism of Dextromethorphan; [Quinidine results in decreased activity of CYP2D6 protein] which results in decreased metabolism of Dextromethorphan; [Tryptamines analog results in decreased activity of CYP2D6 protein] which results in decreased metabolism of Dextromethorphan; Nicardipine inhibits the reaction [CYP2D6 protein results in decreased methylation of Dextromethorphan]; notopterol inhibits the reaction [[CYP2D6 protein results in increased metabolism of Dextromethorphan] which results in increased chemical synthesis of Dextrorphan]; notopterol inhibits the reaction [CYP2D6 protein results in increased metabolism of Dextromethorphan]; Paroxetine inhibits the reaction [CYP2D6 protein results in increased metabolism of Dextromethorphan]; Plant Extracts inhibits the reaction [CYP2D6 protein affects the metabolism of Dextromethorphan]; Quinidine inhibits the reaction [CYP2D6 protein results in increased metabolism of Dextromethorphan]; raubasine inhibits the reaction [CYP2D6 protein affects the metabolism of Dextromethorphan]; Resveratrol inhibits the reaction [CYP2D6 protein results in increased metabolism of Dextromethorphan]; sarpogrelate inhibits the reaction [CYP2D6 protein results in decreased methylation of Dextromethorphan]; sarpogrelate metabolite inhibits the reaction [CYP2D6 protein results in decreased methylation of Dextromethorphan]; serpentine (alkaloid) inhibits the reaction [CYP2D6 protein affects the metabolism of Dextromethorphan]
CYP2D6 gene polymorphism results in increased susceptibility to Dextromethorphan
CTD PMID:9429230 PMID:9429232 PMID:10911933 PMID:11823760 PMID:12433797 More... NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity ISO Dextromethorphan results in decreased activity of CYP2E1 protein CTD PMID:18420780 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases methylation
increases oxidation
increases metabolic processing
multiple interactions
affects metabolic processing
ISO CYP3A4 protein results in decreased methylation of Dextromethorphan
CYP3A4 protein results in increased oxidation of Dextromethorphan
CYP3A4 protein results in increased metabolism of Dextromethorphan
Dextromethorphan inhibits the reaction [[retrorsine co-treated with NADP] results in decreased activity of CYP3A4 protein]
CYP3A4 protein affects the metabolism of Dextromethorphan
CTD PMID:15383492 PMID:15988119 PMID:16595712 PMID:17267297 PMID:19818743 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 affects metabolic processing EXP CYP3A23-3A1 protein affects the metabolism of Dextromethorphan CTD PMID:15879494 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 affects metabolic processing
increases oxidation
decreases methylation
ISO CYP3A5 protein affects the metabolism of Dextromethorphan
CYP3A5 protein results in increased oxidation of Dextromethorphan
CYP3A5 protein results in decreased methylation of Dextromethorphan
CTD PMID:15383492 PMID:15988119 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Cyp46a1 cytochrome P450, family 46, subfamily a, polypeptide 1 decreases methylation ISO CYP46A1 protein results in decreased methylation of Dextromethorphan CTD PMID:14640697 NCBI chr 6:127,247,543...127,274,765
Ensembl chr 6:127,243,315...127,274,760
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
EXP
ISO
Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS mRNA]; Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS protein]; Dizocilpine Maleate inhibits the reaction [Dextromethorphan results in increased expression of FOS protein]; N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS mRNA]]; N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS protein]]; SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS mRNA]]; SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS protein]]; traxoprodil mesylate inhibits the reaction [Dextromethorphan results in increased expression of FOS protein]
Dextromethorphan inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased expression of FOS]
CTD PMID:15084442 PMID:15723099 PMID:28916251 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit affects expression
multiple interactions
ISO Dextromethorphan affects the expression of GCLC mRNA
PRKCD protein affects the reaction [Dextromethorphan affects the expression of GCLC mRNA]; rostafuroxin affects the reaction [Dextromethorphan affects the expression of GCLC mRNA]; rottlerin affects the reaction [Dextromethorphan affects the expression of GCLC mRNA]; traxoprodil mesylate affects the reaction [Dextromethorphan affects the expression of GCLC mRNA]
CTD PMID:34740715 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions
affects expression
ISO PRKCD protein affects the reaction [Dextromethorphan affects the expression of GCLM mRNA]; rostafuroxin affects the reaction [Dextromethorphan affects the expression of GCLM mRNA]; rottlerin affects the reaction [Dextromethorphan affects the expression of GCLM mRNA]; traxoprodil mesylate affects the reaction [Dextromethorphan affects the expression of GCLM mRNA] CTD PMID:34740715 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO Dextromethorphan inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased activity of GPT protein] CTD PMID:30822415 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 increases expression EXP Dextromethorphan results in increased expression of GRIN1 protein CTD PMID:28916251 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A increases expression EXP Dextromethorphan results in increased expression of GRIN2A protein CTD PMID:28916251 NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B multiple interactions
increases expression
EXP
ISO
Dizocilpine Maleate inhibits the reaction [Dextromethorphan results in increased expression of GRIN2B protein]; traxoprodil mesylate inhibits the reaction [Dextromethorphan results in increased expression of GRIN2B protein]
Dextromethorphan promotes the reaction [PRKCD protein modified form binds to GRIN2B protein]; rostafuroxin inhibits the reaction [Dextromethorphan promotes the reaction [PRKCD protein modified form binds to GRIN2B protein]]; rostafuroxin inhibits the reaction [Dextromethorphan results in increased expression of GRIN2B protein]; rottlerin inhibits the reaction [Dextromethorphan promotes the reaction [PRKCD protein modified form binds to GRIN2B protein]]; traxoprodil mesylate inhibits the reaction [Dextromethorphan promotes the reaction [PRKCD protein modified form binds to GRIN2B protein]]; traxoprodil mesylate inhibits the reaction [Dextromethorphan results in increased expression of GRIN2B protein]
CTD PMID:28916251 PMID:34740715 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
JBrowse link
G Hexb hexosaminidase subunit beta multiple interactions
increases secretion
ISO MRGPRX2 protein affects the reaction [Dextromethorphan results in increased secretion of HEXB protein] CTD PMID:32871113 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
JBrowse link
G Il10 interleukin 10 decreases expression ISO Dextromethorphan results in decreased expression of IL10 protein CTD PMID:19189960 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il6 interleukin 6 decreases expression ISO Dextromethorphan results in decreased expression of IL6 protein CTD PMID:19189960 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP
ISO
Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]; Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of JUN protein]; N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]]; N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of JUN protein]]; SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]]; SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of JUN protein]]
Dextromethorphan inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased expression of JUN]
CTD PMID:15084442 PMID:15723099 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Dextromethorphan results in decreased activity of KCNH2 protein CTD PMID:19034038 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase affects response to substance ISO KIT protein affects the susceptibility to Dextromethorphan CTD PMID:32871113 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO Dextromethorphan results in increased phosphorylation of MAPK1 protein
rostafuroxin inhibits the reaction [Dextromethorphan results in increased phosphorylation of MAPK1 protein]
CTD PMID:34740715 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO rostafuroxin inhibits the reaction [Dextromethorphan results in increased phosphorylation of MAPK3 protein] CTD PMID:34740715 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mrgprx2 MAS related GPR family member X2 affects response to substance
multiple interactions
affects binding
ISO MRGPRX2 protein affects the susceptibility to Dextromethorphan
MRGPRX2 protein affects the reaction [Dextromethorphan results in increased secretion of HEXB protein]
Dextromethorphan binds to MRGPRX2 protein
CTD PMID:32871113 NCBI chr 1:98,116,192...98,135,534 JBrowse link
G Nat2 N-acetyltransferase 2 affects metabolic processing ISO NAT2 protein affects the metabolism of Dextromethorphan CTD PMID:15199075 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO [PRKCD protein affects the susceptibility to Dextromethorphan] which affects the activity of and affects the localization of NFE2L2 protein; [rostafuroxin co-treated with Dextromethorphan] results in increased activity of and affects the localization of NFE2L2 protein; [rottlerin co-treated with Dextromethorphan] results in increased activity of and affects the localization of NFE2L2 protein; [traxoprodil mesylate co-treated with Dextromethorphan] results in increased activity of and affects the localization of NFE2L2 protein; Buthionine Sulfoximine inhibits the reaction [Dextromethorphan results in increased activity of NFE2L2 protein]; Dextromethorphan results in increased activity of and affects the localization of NFE2L2 protein CTD PMID:34740715 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Oprd1 opioid receptor, delta 1 multiple interactions
affects binding
EXP [Dextromethorphan binds to OPRD1 protein] which results in decreased uptake of Norepinephrine; [Dextromethorphan binds to OPRD1 protein] which results in decreased uptake of Serotonin CTD PMID:7562497 NCBI chr 5:144,306,188...144,340,960
Ensembl chr 5:144,306,188...144,340,960
JBrowse link
G Oprk1 opioid receptor, kappa 1 affects binding
multiple interactions
EXP Dextromethorphan binds to OPRK1 protein
[Dextromethorphan binds to OPRK1 protein] which results in decreased uptake of Norepinephrine; [Dextromethorphan binds to OPRK1 protein] which results in decreased uptake of Serotonin
CTD PMID:7562497 NCBI chr 5:13,860,016...13,877,823
Ensembl chr 5:13,860,021...13,877,823
JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions
affects binding
EXP [Dextromethorphan binds to OPRM1 protein] which results in decreased uptake of Norepinephrine; [Dextromethorphan binds to OPRM1 protein] which results in decreased uptake of Serotonin CTD PMID:7562497 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
JBrowse link
G Prkcd protein kinase C, delta multiple interactions
affects response to substance
ISO [PRKCD protein affects the susceptibility to Dextromethorphan] which affects the activity of and affects the localization of NFE2L2 protein; Dextromethorphan promotes the reaction [PRKCD protein modified form binds to GRIN2B protein]; Dextromethorphan results in increased expression of and results in increased phosphorylation of PRKCD protein; PRKCD protein affects the reaction [Dextromethorphan affects the expression of GCLC mRNA]; PRKCD protein affects the reaction [Dextromethorphan affects the expression of GCLM mRNA]; rostafuroxin inhibits the reaction [Dextromethorphan promotes the reaction [PRKCD protein modified form binds to GRIN2B protein]]; rostafuroxin inhibits the reaction [Dextromethorphan results in increased phosphorylation of PRKCD protein]; rottlerin inhibits the reaction [Dextromethorphan promotes the reaction [PRKCD protein modified form binds to GRIN2B protein]]; rottlerin inhibits the reaction [Dextromethorphan results in increased phosphorylation of PRKCD protein]; traxoprodil mesylate inhibits the reaction [Dextromethorphan promotes the reaction [PRKCD protein modified form binds to GRIN2B protein]]; traxoprodil mesylate inhibits the reaction [Dextromethorphan results in increased phosphorylation of PRKCD protein] CTD PMID:34740715 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Dextromethorphan inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:15987631 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
affects activity
ISO Buthionine Sulfoximine affects the reaction [Dextromethorphan affects the activity of RELA protein] CTD PMID:34740715 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Sigmar1 sigma non-opioid intracellular receptor 1 multiple interactions
affects binding
EXP SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS mRNA]]; SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS protein]]; SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]]; SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of JUN protein]]
Dextromethorphan binds to SIGMAR1 protein
CTD PMID:15723099 NCBI chr 5:56,904,155...56,907,012
Ensembl chr 5:56,904,159...56,907,017
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Dextromethorphan inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Slc6a4 solute carrier family 6 member 4 multiple interactions EXP Dextromethorphan inhibits the reaction [Excitatory Amino Acid Agonists results in decreased expression of SLC6A4 protein] CTD PMID:31153898 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
JBrowse link
G Sord sorbitol dehydrogenase multiple interactions ISO Dextromethorphan inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased activity of SORD protein] CTD PMID:30822415 NCBI chr 3:109,184,697...109,216,133
Ensembl chr 3:109,184,676...109,216,133
JBrowse link
G Tgfa transforming growth factor alpha multiple interactions ISO Dextromethorphan inhibits the reaction [Lipopolysaccharides results in increased secretion of TGFA] CTD PMID:15987631 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
JBrowse link
G Tnf tumor necrosis factor decreases expression
increases secretion
multiple interactions
ISO Dextromethorphan results in decreased expression of TNF protein
Dextromethorphan results in increased secretion of TNF protein
Dextromethorphan inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased expression of TNF protein]; Dextromethorphan inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]
CTD PMID:19189960 PMID:30822415 PMID:32871113 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Xdh xanthine dehydrogenase affects metabolic processing ISO XDH protein affects the metabolism of Dextromethorphan CTD PMID:15199075 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
JBrowse link
dimenhydrinate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bche butyrylcholinesterase decreases activity ISO Dimenhydrinate results in decreased activity of BCHE protein CTD PMID:236606 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Dimenhydrinate inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
diphenhydramine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg5 autophagy related 5 affects response to substance ISO ATG5 protein affects the susceptibility to Diphenhydramine CTD PMID:22310178 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Bche butyrylcholinesterase multiple interactions
decreases activity
ISO Protons affects the reaction [Diphenhydramine results in decreased activity of BCHE protein] CTD PMID:236606 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Bmp6 bone morphogenetic protein 6 decreases expression ISO Diphenhydramine results in decreased expression of BMP6 mRNA CTD PMID:32816093 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G Ereg epiregulin decreases expression ISO Diphenhydramine results in decreased expression of EREG mRNA CTD PMID:32816093 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO Diphenhydramine inhibits the reaction [Histamine results in increased expression of F3] CTD PMID:16009787 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Gnai1 G protein subunit alpha i1 increases response to substance ISO GNAI1 results in increased susceptibility to Diphenhydramine CTD PMID:14614911 NCBI chr 4:16,814,000...16,898,119
Ensembl chr 4:16,814,001...16,896,417
JBrowse link
G Gnai2 G protein subunit alpha i2 increases response to substance ISO GNAI2 results in increased susceptibility to Diphenhydramine CTD PMID:14614911 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
JBrowse link
G Hrh1 histamine receptor H 1 multiple interactions ISO
EXP
Diphenhydramine binds to and results in decreased activity of HRH1 protein; Diphenhydramine binds to and results in increased activity of HRH1 protein; Diphenhydramine inhibits the reaction [Pyrilamine binds to HRH1 protein]; HRH1 protein promotes the reaction [Diphenhydramine results in decreased susceptibility to CXCL8 protein]
[Diphenhydramine results in decreased activity of HRH1 protein] which results in decreased susceptibility to Erythromycin
CTD PMID:1912125 PMID:2419744 PMID:2461127 PMID:7522859 PMID:9609743 More... NCBI chr 4:147,564,963...147,649,353
Ensembl chr 4:147,645,995...147,647,455
JBrowse link
G Il1b interleukin 1 beta increases expression
decreases expression
ISO Diphenhydramine results in increased expression of IL1B mRNA
Diphenhydramine results in decreased expression of IL1B mRNA
CTD PMID:28138970 PMID:32816093 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il24 interleukin 24 decreases expression ISO Diphenhydramine results in decreased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487
JBrowse link
G Il6 interleukin 6 multiple interactions ISO Diphenhydramine inhibits the reaction [Histamine results in increased expression of IL6 protein] CTD PMID:11336536 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases activity ISO Diphenhydramine results in increased activity of MAPK8 CTD PMID:17390763 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO [Diphenhydramine co-treated with PK 11195] binds to and results in increased activity of NR1I3 protein alternative form CTD PMID:20869355 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Pla2g4a phospholipase A2 group IVA multiple interactions ISO Diphenhydramine inhibits the reaction [Histamine results in increased expression of PLA2G4A mRNA] CTD PMID:9609743 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Diphenhydramine results in decreased expression of PTGS2 mRNA CTD PMID:32816093 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Slc22a1 solute carrier family 22 member 1 multiple interactions ISO Diphenhydramine inhibits the reaction [SLC22A1 protein results in increased transport of 1-Methyl-4-phenylpyridinium] CTD PMID:16263091 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Diphenhydramine inhibits the reaction [SLC22A2 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Diphenhydramine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:16263091 PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions ISO Diphenhydramine inhibits the reaction [SLC22A3 protein results in increased transport of 1-Methyl-4-phenylpyridinium] CTD PMID:16263091 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612
JBrowse link
G Slc22a5 solute carrier family 22 member 5 multiple interactions ISO Diphenhydramine affects the reaction [SLC22A5 gene mutant form affects the transport of and affects the abundance of Pyrilamine]; Diphenhydramine inhibits the reaction [SLC22A5 gene mutant form affects the transport of and affects the abundance of Pyrilamine] CTD PMID:19821448 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309
JBrowse link
G Slc7a11 solute carrier family 7 member 11 decreases expression ISO Diphenhydramine results in decreased expression of SLC7A11 mRNA CTD PMID:32816093 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Diphenhydramine results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453
JBrowse link
harmaline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO Harmaline inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL2 protein] CTD PMID:12107048 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Cdh1 cadherin 1 increases expression ISO Harmaline results in increased expression of CDH1 protein CTD PMID:35963316 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
decreases activity
decreases stability
ISO [Cycloheximide co-treated with Harmaline] results in decreased expression of CYP1A1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Cycloheximide co-treated with Harmaline] results in decreased expression of CYP1A1 protein]; Harmaline inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A1 protein]; Harmaline inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A1 protein]; Harmaline inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
Harmaline results in decreased activity of CYP1A1 protein
Harmaline results in decreased stability of CYP1A1 protein
CTD PMID:22037238 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Eng endoglin decreases expression
multiple interactions
ISO Harmaline results in decreased expression of ENG mRNA
Doxorubicin promotes the reaction [Harmaline results in decreased expression of ENG mRNA]
CTD PMID:35963316 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
JBrowse link
G Ifng interferon gamma increases secretion ISO Harmaline results in increased secretion of IFNG protein CTD PMID:35963316 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Harmaline inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]; Harmaline inhibits the reaction [IL1B protein results in increased secretion of CXCL8 protein] CTD PMID:12065299 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il4 interleukin 4 affects secretion
multiple interactions
ISO Harmaline affects the secretion of IL4 protein
Doxorubicin affects the reaction [Harmaline results in decreased secretion of IL4 protein]
CTD PMID:35963316 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Kdr kinase insert domain receptor multiple interactions
decreases expression
ISO Doxorubicin promotes the reaction [Harmaline results in decreased expression of KDR mRNA] CTD PMID:35963316 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Maoa monoamine oxidase A decreases activity EXP
ISO
Harmaline results in decreased activity of MAOA protein CTD PMID:15178694 PMID:24373881 PMID:28302559 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO Harmaline results in decreased expression of MKI67 protein CTD PMID:35963316 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression ISO Harmaline results in decreased expression of MMP2 protein CTD PMID:35963316 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO Harmaline inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]; Harmaline inhibits the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of and results in increased activity of NFKB1 protein] CTD PMID:12065299 PMID:12107048 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression
ISO Doxorubicin promotes the reaction [Harmaline results in decreased expression of PTGS2 mRNA] CTD PMID:35963316 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Harmaline inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]; Harmaline inhibits the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of and results in increased activity of RELA protein] CTD PMID:12065299 PMID:12107048 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
decreases expression
ISO Doxorubicin promotes the reaction [Harmaline results in decreased expression of VEGFA mRNA]
Harmaline results in decreased expression of VEGFA mRNA; Harmaline results in decreased expression of VEGFA protein
CTD PMID:35963316 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
ibogaine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Ibogaine results in decreased activity of KCNH2 protein CTD PMID:23707769 PMID:24307198 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 decreases activity ISO Ibogaine results in decreased activity of SCN5A protein CTD PMID:23707769 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769
JBrowse link
G Sec24d SEC24 homolog D, COPII coat complex component increases response to substance ISO SEC24D protein results in increased susceptibility to Ibogaine CTD PMID:27555326 NCBI chr 2:211,418,557...211,526,588
Ensembl chr 2:211,418,623...211,526,587
JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions
increases expression
ISO Ibogaine inhibits the reaction [SLC6A3 protein mutant form results in decreased import of Dopamine]; Ibogaine promotes the reaction [SLC6A3 protein results in increased import of Dopamine]
Ibogaine results in increased expression of SLC6A3 protein
CTD PMID:27555326 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
mirtazapine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases export ISO ABCB1 protein results in increased export of mirtazapine CTD PMID:14550684 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO mirtazapine inhibits the reaction [Thioacetamide results in increased expression of ACTA2 protein] CTD PMID:28623179 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
multiple interactions
EXP Mirtazapine results in decreased phosphorylation of AKT1 protein
Ethanol promotes the reaction [Mirtazapine results in decreased phosphorylation of AKT1 protein]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in decreased phosphorylation of AKT1 protein]]; HMGB1 protein affects the reaction [Mirtazapine results in decreased phosphorylation of AKT1 protein]
CTD PMID:35066094 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Atg7 autophagy related 7 multiple interactions
increases expression
EXP
ISO
Ethanol promotes the reaction [Mirtazapine results in increased expression of ATG7 mRNA]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of ATG7 mRNA]]; HMGB1 protein affects the reaction [Mirtazapine results in increased expression of ATG7 mRNA] CTD PMID:35066094 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Becn1 beclin 1 multiple interactions
increases expression
ISO
EXP
Ethanol promotes the reaction [Mirtazapine results in increased expression of BECN1 protein]
3-methyladenine inhibits the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of BECN1 protein]]; 3-methyladenine inhibits the reaction [Mirtazapine results in increased expression of BECN1 protein]; Ethanol promotes the reaction [Mirtazapine results in increased expression of BECN1 protein]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of BECN1 protein]]; HMGB1 protein affects the reaction [Mirtazapine results in increased expression of BECN1 protein]
CTD PMID:35066094 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Cat catalase multiple interactions EXP mirtazapine inhibits the reaction [Indomethacin results in increased activity of CAT protein] CTD PMID:19034656 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions
increases expression
ISO
EXP
Ethanol promotes the reaction [Mirtazapine results in increased expression of COL1A1 mRNA]
3-methyladenine inhibits the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of COL1A1 mRNA]]; 3-methyladenine inhibits the reaction [Mirtazapine results in increased expression of COL1A1 mRNA]; Ethanol promotes the reaction [Mirtazapine results in increased expression of COL1A1 mRNA]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of COL1A1 mRNA]]; HMGB1 protein affects the reaction [Mirtazapine results in increased expression of COL1A1 mRNA]
CTD PMID:35066094 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Drd1 dopamine receptor D1 increases expression EXP mirtazapine results in increased expression of DRD1 mRNA CTD PMID:16499906 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions EXP mirtazapine inhibits the reaction [Quinpirole binds to DRD2 protein] CTD PMID:12523492 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Drd3 dopamine receptor D3 multiple interactions EXP mirtazapine inhibits the reaction [Quinpirole binds to DRD3 protein] CTD PMID:12523492 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases expression
ISO Ethanol promotes the reaction [Mirtazapine results in increased expression of GPT protein] CTD PMID:35066094 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions
increases expression
EXP Ethanol promotes the reaction [Mirtazapine results in increased expression of HMGB1 protein]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in decreased expression of LAMP1 protein]]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in decreased phosphorylation of AKT1 protein]]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in decreased phosphorylation of MTOR protein]]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of ATG7 mRNA]]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of BECN1 protein]]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of COL1A1 mRNA]]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of NPPB mRNA]]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of PIK3C3 protein]]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of SQSTM1 protein]]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of TGFB1 mRNA]]; HMGB1 protein affects the reaction [Mirtazapine results in decreased expression of LAMP1 protein]; HMGB1 protein affects the reaction [Mirtazapine results in decreased phosphorylation of AKT1 protein]; HMGB1 protein affects the reaction [Mirtazapine results in decreased phosphorylation of MTOR protein]; HMGB1 protein affects the reaction [Mirtazapine results in increased expression of ATG7 mRNA]; HMGB1 protein affects the reaction [Mirtazapine results in increased expression of BECN1 protein]; HMGB1 protein affects the reaction [Mirtazapine results in increased expression of COL1A1 mRNA]; HMGB1 protein affects the reaction [Mirtazapine results in increased expression of NPPB mRNA]; HMGB1 protein affects the reaction [Mirtazapine results in increased expression of PIK3C3 protein]; HMGB1 protein affects the reaction [Mirtazapine results in increased expression of SQSTM1 protein]; HMGB1 protein affects the reaction [Mirtazapine results in increased expression of TGFB1 mRNA] CTD PMID:35066094 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO mirtazapine results in increased expression of HMGCS1 mRNA CTD PMID:16324787 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C multiple interactions
increases expression
ISO 6-chloro-5-methyl-1-((2-(2-methylpyrid-3-yloxy)pyrid-5-yl)carbamoyl)indoline inhibits the reaction [mirtazapine results in increased expression of HTR2C protein]; mirtazapine binds to and affects the activity of HTR2C protein CTD PMID:18083778 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP Mirtazapine inhibits the reaction [Cadmium results in increased expression of IL1B protein] CTD PMID:37403423 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions EXP Mirtazapine inhibits the reaction [Cadmium results in increased expression of IL6 protein] CTD PMID:37403423 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 multiple interactions ISO mirtazapine affects the activity of [KCNJ3 mRNA co-treated with KCNJ5 mRNA]; mirtazapine affects the activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA] CTD PMID:22164246 NCBI chr 3:39,944,896...40,106,646
Ensembl chr 3:39,945,351...40,109,124
JBrowse link
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 multiple interactions ISO mirtazapine affects the activity of [KCNJ3 mRNA co-treated with KCNJ5 mRNA] CTD PMID:22164246 NCBI chr 8:30,724,923...30,753,083
Ensembl chr 8:30,724,925...30,753,518
JBrowse link
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 multiple interactions ISO mirtazapine affects the activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA] CTD PMID:22164246 NCBI chr11:34,061,702...34,308,758
Ensembl chr11:34,061,708...34,308,758
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 multiple interactions
decreases expression
EXP Ethanol promotes the reaction [Mirtazapine results in decreased expression of LAMP1 protein]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in decreased expression of LAMP1 protein]]; HMGB1 protein affects the reaction [Mirtazapine results in decreased expression of LAMP1 protein] CTD PMID:35066094 NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP mirtazapine inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:19034656 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation
multiple interactions
EXP Mirtazapine results in decreased phosphorylation of MTOR protein
Ethanol promotes the reaction [Mirtazapine results in decreased phosphorylation of MTOR protein]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in decreased phosphorylation of MTOR protein]]; HMGB1 protein affects the reaction [Mirtazapine results in decreased phosphorylation of MTOR protein]
CTD PMID:35066094 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression EXP Mirtazapine results in increased expression of NFE2L2 protein CTD PMID:37403423 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nox1 NADPH oxidase 1 multiple interactions ISO mirtazapine inhibits the reaction [Thioacetamide results in increased expression of NOX1 protein] CTD PMID:28623179 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236
JBrowse link
G Nppb natriuretic peptide B increases expression
multiple interactions
ISO
EXP
Mirtazapine results in increased expression of NPPB mRNA
Ethanol promotes the reaction [Mirtazapine results in increased expression of NPPB mRNA]
3-methyladenine inhibits the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of NPPB mRNA]]; 3-methyladenine inhibits the reaction [Mirtazapine results in increased expression of NPPB mRNA]; Ethanol promotes the reaction [Mirtazapine results in increased expression of NPPB mRNA]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of NPPB mRNA]]; HMGB1 protein affects the reaction [Mirtazapine results in increased expression of NPPB mRNA]
CTD PMID:35066094 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 increases expression
multiple interactions
EXP Mirtazapine results in increased expression of PIK3C3 protein
3-methyladenine inhibits the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of PIK3C3 protein]]; 3-methyladenine inhibits the reaction [Mirtazapine results in increased expression of PIK3C3 protein]; Ethanol promotes the reaction [Mirtazapine results in increased expression of PIK3C3 protein]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of PIK3C3 protein]]; HMGB1 protein affects the reaction [Mirtazapine results in increased expression of PIK3C3 protein]
CTD PMID:35066094 NCBI chr18:21,845,282...21,934,387
Ensembl chr18:21,845,295...21,929,048
JBrowse link
G Prl prolactin increases expression ISO mirtazapine results in increased expression of PRL protein CTD PMID:15105766 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit decreases expression EXP Mirtazapine results in decreased expression of RELA protein CTD PMID:37403423 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Scd stearoyl-CoA desaturase increases expression ISO mirtazapine results in increased expression of SCD mRNA CTD PMID:16324787 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO mirtazapine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression ISO mirtazapine results in increased expression of SLC2A4 mRNA CTD PMID:16002093 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Slc2a5 solute carrier family 2 member 5 increases expression ISO mirtazapine results in increased expression of SLC2A5 mRNA CTD PMID:16002093 NCBI chr 5:160,583,055...160,609,994
Ensembl chr 5:160,583,234...160,611,106
JBrowse link
G Smad3 SMAD family member 3 multiple interactions ISO mirtazapine inhibits the reaction [Thioacetamide results in increased expression of SMAD3 protein modified form] CTD PMID:28623179 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Sqstm1 sequestosome 1 increases expression
multiple interactions
EXP
ISO
Mirtazapine results in increased expression of SQSTM1 protein
Ethanol promotes the reaction [Mirtazapine results in increased expression of SQSTM1 protein]
3-methyladenine inhibits the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of SQSTM1 protein]]; 3-methyladenine inhibits the reaction [Mirtazapine results in increased expression of SQSTM1 protein]; Ethanol promotes the reaction [Mirtazapine results in increased expression of SQSTM1 protein]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of SQSTM1 protein]]; HMGB1 protein affects the reaction [Mirtazapine results in increased expression of SQSTM1 protein]
CTD PMID:35066094 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO mirtazapine results in increased cleavage of and results in increased activity of SREBF1 protein CTD PMID:16324787 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
increases expression
ISO
EXP
Ethanol promotes the reaction [Mirtazapine results in increased expression of TGFB1 mRNA]; Mirtazapine inhibits the reaction [Thioacetamide results in increased expression of TGFB1 protein]
Ethanol promotes the reaction [Mirtazapine results in increased expression of TGFB1 mRNA]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of TGFB1 mRNA]]; HMGB1 protein affects the reaction [Mirtazapine results in increased expression of TGFB1 mRNA]
CTD PMID:28623179 PMID:35066094 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tlr4 toll-like receptor 4 decreases expression EXP Mirtazapine results in decreased expression of TLR4 protein CTD PMID:37403423 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP Mirtazapine inhibits the reaction [Cadmium results in increased expression of TNF protein] CTD PMID:37403423 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
muscimol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor multiple interactions EXP Muscimol inhibits the reaction [decamethrin results in increased expression of BDNF exon] CTD PMID:22079160 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Casp3 caspase 3 multiple interactions ISO Muscimol inhibits the reaction [Ethanol results in increased cleavage of CASP3 protein] CTD PMID:29044621 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit multiple interactions ISO Muscimol binds to and results in increased activity of [CHRNA5 protein co-treated with CHRNB1 protein] CTD PMID:8388298 NCBI chr 8:55,369,794...55,398,526
Ensembl chr 8:55,369,794...55,398,146
JBrowse link
G Chrnb1 cholinergic receptor nicotinic beta 1 subunit multiple interactions ISO Muscimol binds to and results in increased activity of [CHRNA5 protein co-treated with CHRNB1 protein] CTD PMID:8388298 NCBI chr10:54,501,096...54,516,418
Ensembl chr10:54,501,093...54,516,345
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO Muscimol inhibits the reaction [Ethanol results in increased phosphorylation of ERN1 protein] CTD PMID:29044621 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Muscimol inhibits the reaction [Cocaine results in increased expression of FOS protein] CTD PMID:16930414 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions
decreases expression
EXP Muscimol inhibits the reaction [Diethylhexyl Phthalate results in increased expression of FSHB protein]
Muscimol results in decreased expression of FSHB protein
CTD PMID:29774754 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions
affects binding
ISO GABRA1 protein affects the reaction [Muscimol results in increased uptake of Chlorides]
Muscimol binds to [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]
2,6-diisopropyl-4-(3-(3-methyl-3H-diazirin-3-yl)propyl)phenol promotes the reaction [Muscimol binds to [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Propofol affects the reaction [Muscimol binds to [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]
CTD PMID:12490572 PMID:22029276 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 affects binding EXP Muscimol binds to GABRB1 protein CTD PMID:9661255 NCBI chr14:36,068,725...36,548,946
Ensembl chr14:36,080,393...36,548,948
JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 multiple interactions
affects binding
ISO
EXP
GABRB2 protein affects the reaction [Muscimol results in increased uptake of Chlorides]
alphaxalone promotes the reaction [Muscimol binds to GABRB2 protein]; Pentobarbital affects the reaction [GABRB2 protein binds to Muscimol]; Pentobarbital promotes the reaction [Muscimol binds to GABRB2 protein]
GABRB2 protein binds to Muscimol; Muscimol binds to GABRB2 protein
CTD PMID:8397295 PMID:10591412 PMID:12490572 NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251
JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 multiple interactions
affects binding
EXP
ISO
alphaxalone promotes the reaction [Muscimol binds to GABRB3 protein]; Pentobarbital promotes the reaction [Muscimol binds to GABRB3 protein]
2,6-diisopropyl-4-(3-(3-methyl-3H-diazirin-3-yl)propyl)phenol promotes the reaction [Muscimol binds to [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Propofol affects the reaction [Muscimol binds to [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]
CTD PMID:8397295 PMID:22029276 NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 multiple interactions
affects binding
ISO 2,6-diisopropyl-4-(3-(3-methyl-3H-diazirin-3-yl)propyl)phenol promotes the reaction [Muscimol binds to [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Propofol affects the reaction [Muscimol binds to [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] CTD PMID:22029276 NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346
JBrowse link
G Gabrr3 gamma-aminobutyric acid type A receptor subunit rho3 increases activity EXP Muscimol results in increased activity of GABRR3 protein CTD PMID:10635063 NCBI chr11:40,902,812...40,955,263
Ensembl chr11:40,902,812...40,955,263
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 multiple interactions EXP Muscimol affects the reaction [bisphenol A affects the secretion of GNRH1 protein] CTD PMID:26950200 NCBI chr15:41,972,482...41,976,690
Ensembl chr15:41,972,905...41,973,581
Ensembl chr15:41,972,905...41,973,581
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO Muscimol inhibits the reaction [Ethanol results in increased activity of GPT protein] CTD PMID:29044621 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Lhb luteinizing hormone subunit beta decreases expression EXP Muscimol results in decreased expression of LHB protein CTD PMID:29774754 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 multiple interactions ISO Muscimol inhibits the reaction [Ethanol results in increased expression of MAP3K5 protein] CTD PMID:29044621 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP Muscimol promotes the reaction [methyl tert-butyl ether results in decreased phosphorylation of MAPK1 protein] CTD PMID:19344668 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP Muscimol promotes the reaction [methyl tert-butyl ether results in decreased phosphorylation of MAPK3 protein] CTD PMID:19344668 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO Muscimol inhibits the reaction [Ethanol results in increased expression of MAPK8 protein] CTD PMID:29044621 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Pomc proopiomelanocortin multiple interactions
decreases expression
EXP Muscimol promotes the reaction [Pentobarbital results in decreased expression of POMC mRNA]
Muscimol results in decreased expression of POMC mRNA
CTD PMID:7937335 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
G Syn1 synapsin I decreases expression EXP Muscimol results in decreased expression of SYN1 protein CTD PMID:21920406 NCBI chr  X:1,172,208...1,227,400
Ensembl chr  X:1,172,208...1,227,396
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19831
    role 19807
      application 19650
        pharmaceutical 19491
          drug 19491
            central nervous system drug 16778
              psychotropic drug 15558
                oneirogen 520
                  atropine + 95
                  benzatropine + 329
                  dextromethorphan + 51
                  diphenhydramine + 21
                  harmaline 15
                  ibogaine + 4
                  ibogamine + 4
                  mirtazapine 38
                  muscimol 22
                  salvinorin A 0
paths to the root