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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:145924 term browser browse the term
Definition:A mixture containing lopinavir and ritonavir. It is a prescription medicine that is used with other antiretroviral medicines to treat Human Immunodeficiency Virus-1 (HIV-1) infection in adults and children 14 days of age and older.
Synonyms:related_synonym: ABT-378 & ABT-538;   Aluvia;   Formula=C37H48N6O5S2.C37H48N4O5;   InChI=1S/C37H48N6O5S2.C37H48N4O5/c1-24(2)33(42-36(46)43(5)20-29-22-49-35(40-29)25(3)4)34(45)39-28(16-26-12-8-6-9-13-26)18-32(44)31(17-27-14-10-7-11-15-27)41-37(47)48-21-30-19-38-23-50-30;1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h6-15,19,22-25,28,31-33,44H,16-18,20-21H2,1-5H3,(H,39,45)(H,41,47)(H,42,46);5-11,13-18,25,30-32,34,42H,12,19-24H2,1-4H3,(H,38,45)(H,39,44)(H,40,43)/t28-,31-,32-,33-;30-,31-,32-,34-/m00/s1;   InChIKey=OFFWOVJBSQMVPI-RMLGOCCBSA-N;   Lopimune;   SMILES=C1=CC=CC(C[C@@H](C[C@@H]([C@@H](NC(=O)COC=2C(=CC=CC2C)C)CC3=CC=CC=C3)O)NC(=O)[C@H](C(C)C)N4CCCNC4=O)=C1.[C@H](CC1=CC=CC=C1)(C[C@@H]([C@H](CC2=CC=CC=C2)NC(OCC3=CN=CS3)=O)O)NC([C@@H](NC(N(CC=4N=C(C(C)C)SC4)C)=O)C(C)C)=O;   lopinavir and ritonavir;   lopinavir mixture with ritonavir;   lopinavir-ritonavir mixt;   lopinavir/ritonavir;   ritonavir and lopinavir mixture;   ritonavir-boosted lopinavir
 xref: CAS:369372-47-4;   KEGG:D02498;   PMCID:PMC6255574;   PMID:17565464;   PMID:19480095;   PMID:24516081;   PMID:25656621;   PMID:26953282;   PMID:29136115;   PMID:29584910;   PMID:29602711;   PMID:29959798;   PMID:30174599;   PMID:30346663;   PMID:30549217;   PMID:30798695;   PMID:30814028;   PMID:30909871;   PMID:30995874;   PMID:31081020;   PMID:31139825;   PMID:31334298;   PMID:31490959;   PMID:31612827;   PMID:31704214;   PMID:31920659;   Wikipedia:Lopinavir/ritonavir

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  CHEBI ontology 19883
    chemical entity 19883
      chemical substance 12203
        mixture 11151
          Kaletra 0
Path 2
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  CHEBI ontology 19883
    subatomic particle 19881
      composite particle 19881
        hadron 19881
          baryon 19881
            nucleon 19881
              atomic nucleus 19881
                atom 19881
                  main group element atom 19771
                    p-block element atom 19771
                      carbon group element atom 19679
                        carbon atom 19668
                          organic molecular entity 19668
                            organic group 18580
                              organic divalent group 18571
                                organodiyl group 18571
                                  carbonyl group 18479
                                    carbonyl compound 18479
                                      carboxylic acid 18153
                                        carboacyl group 17410
                                          univalent carboacyl group 17410
                                            carbamoyl group 17192
                                              carboxamide 17192
                                                monocarboxylic acid amide 14620
                                                  urea 5013
                                                    ureas 5010
                                                      ritonavir 109
                                                        Kaletra 0
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