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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:methyl 3,4,5-trihydroxybenzoate
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Accession:CHEBI:145828 term browser browse the term
Definition:A gallate ester obtained by the formal condensation of gallic acid with methanol. It exhibits anti-oxidant, anti-tumor, anti-microbial and anti-inflammatory properties.
Synonyms:related_synonym: 3,4,5-trihydroxy-benzoic acid methyl ester;   Formula=C8H8O5;   InChI=1S/C8H8O5/c1-13-8(12)4-2-5(9)7(11)6(10)3-4/h2-3,9-11H,1H3;   InChIKey=FBSFWRHWHYMIOG-UHFFFAOYSA-N;   SMILES=OC1=CC(=CC(O)=C1O)C(OC)=O;   gallic acid methyl ester;   methyl gallate;   methylgallate
 xref: CAS:99-24-1;   FooDB:FDB000663;   KNApSAcK:C00030754
 xref_mesh: MESH:C052082
 xref: PMID:10346950;   PMID:12094296;   PMID:2437251;   PMID:27227459;   PMID:27592552;   PMID:28272351;   PMID:2840133;   PMID:28744880;   PMID:29116460;   PMID:29120784;   PMID:29847215;   PMID:30314293;   PMID:30886338;   PMID:31151650;   PMID:31557976;   PMID:31890180;   Reaxys:2113180;   Wikipedia:Methyl_gallate

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methyl 3,4,5-trihydroxybenzoate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmox1 heme oxygenase 1 increases expression ISO methyl gallate results in increased expression of HMOX1 mRNA CTD PMID:27777014 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456 		JBrowse link
G Il10 interleukin 10 decreases expression ISO methyl gallate results in decreased expression of IL10 protein CTD PMID:32112863 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392 		JBrowse link
G Il12a interleukin 12A multiple interactions ISO methyl gallate results in increased expression of [IL12A protein binds to IL12B protein] CTD PMID:32112863 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318 		JBrowse link
G Il12b interleukin 12B multiple interactions ISO methyl gallate results in increased expression of [IL12A protein binds to IL12B protein] CTD PMID:32112863 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085 		JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases expression ISO methyl gallate results in increased expression of NFE2L2 protein CTD PMID:27777014 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996 		JBrowse link
G Tnf tumor necrosis factor increases expression ISO methyl gallate results in increased expression of TNF protein CTD PMID:32112863 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19720
      chemical role 19260
        antioxidant 14254
          methyl 3,4,5-trihydroxybenzoate 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19662
                    p-block element atom 19662
                      carbon group element atom 19580
                        carbon atom 19571
                          organic molecular entity 19571
                            organic group 18602
                              organic divalent group 18593
                                organodiyl group 18593
                                  carbonyl group 18506
                                    carbonyl compound 18506
                                      carboxylic acid 18158
                                        aromatic carboxylic acid 11263
                                          benzoic acids 11234
                                            benzoic acid 3861
                                              hydroxybenzoic acid 3249
                                                trihydroxybenzoic acid 2313
                                                  gallic acid 2296
                                                    gallate ester 2194
                                                      methyl 3,4,5-trihydroxybenzoate 6
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