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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:methyl 3,4,5-trihydroxybenzoate
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Accession:CHEBI:145828 term browser browse the term
Definition:A gallate ester obtained by the formal condensation of gallic acid with methanol. It exhibits anti-oxidant, anti-tumor, anti-microbial and anti-inflammatory properties.
Synonyms:related_synonym: 3,4,5-trihydroxy-benzoic acid methyl ester;   Formula=C8H8O5;   InChI=1S/C8H8O5/c1-13-8(12)4-2-5(9)7(11)6(10)3-4/h2-3,9-11H,1H3;   InChIKey=FBSFWRHWHYMIOG-UHFFFAOYSA-N;   SMILES=OC1=CC(=CC(O)=C1O)C(OC)=O;   gallic acid methyl ester;   methyl gallate;   methylgallate
 xref: CAS:99-24-1;   FooDB:FDB000663;   KNApSAcK:C00030754
 xref_mesh: MESH:C052082
 xref: PMID:10346950;   PMID:12094296;   PMID:2437251;   PMID:27227459;   PMID:27592552;   PMID:28272351;   PMID:2840133;   PMID:28744880;   PMID:29116460;   PMID:29120784;   PMID:29847215;   PMID:30314293;   PMID:30886338;   PMID:31151650;   PMID:31557976;   PMID:31890180;   Reaxys:2113180;   Wikipedia:Methyl_gallate


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methyl 3,4,5-trihydroxybenzoate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmox1 heme oxygenase 1 increases expression ISO methyl gallate results in increased expression of HMOX1 mRNA CTD PMID:27777014 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Il10 interleukin 10 decreases expression ISO methyl gallate results in decreased expression of IL10 protein CTD PMID:32112863 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il12a interleukin 12A multiple interactions ISO methyl gallate results in increased expression of [IL12A protein binds to IL12B protein] CTD PMID:32112863 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734 		JBrowse link
G Il12b interleukin 12B multiple interactions ISO methyl gallate results in increased expression of [IL12A protein binds to IL12B protein] CTD PMID:32112863 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression ISO methyl gallate results in increased expression of NFE2L2 protein CTD PMID:27777014 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Tnf tumor necrosis factor increases expression ISO methyl gallate results in increased expression of TNF protein CTD PMID:32112863 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19818
    role 19790
      chemical role 19421
        antioxidant 15726
          methyl 3,4,5-trihydroxybenzoate 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19818
    subatomic particle 19816
      composite particle 19816
        hadron 19816
          baryon 19816
            nucleon 19816
              atomic nucleus 19816
                atom 19816
                  main group element atom 19761
                    p-block element atom 19761
                      carbon group element atom 19703
                        carbon atom 19698
                          organic molecular entity 19698
                            organic group 18905
                              organic divalent group 18887
                                organodiyl group 18887
                                  carbonyl group 18853
                                    carbonyl compound 18853
                                      carboxylic acid 18569
                                        aromatic carboxylic acid 11830
                                          benzoic acids 11805
                                            benzoic acid 4374
                                              hydroxybenzoic acid 3784
                                                trihydroxybenzoic acid 2714
                                                  gallic acid 2701
                                                    gallate ester 2272
                                                      methyl 3,4,5-trihydroxybenzoate 6
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