CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: methyl 3,4,5-trihydroxybenzoate
Accession: CHEBI:145828
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Definition: A gallate ester obtained by the formal condensation of gallic acid with methanol. It exhibits anti-oxidant, anti-tumor, anti-microbial and anti-inflammatory properties.
Synonyms: related_synonym: 3,4,5-trihydroxy-benzoic acid methyl ester; Formula=C8H8O5; InChI=1S/C8H8O5/c1-13-8(12)4-2-5(9)7(11)6(10)3-4/h2-3,9-11H,1H3; InChIKey=FBSFWRHWHYMIOG-UHFFFAOYSA-N; SMILES=OC1=CC(=CC(O)=C1O)C(OC)=O; gallic acid methyl ester; methyl gallate; methylgallate
xref: CAS:99-24-1; FooDB:FDB000663; KNApSAcK:C00030754
xref_mesh: MESH:C052082
xref: PMID:10346950; PMID:12094296; PMID:2437251; PMID:27227459; PMID:27592552; PMID:28272351; PMID:2840133; PMID:28744880; PMID:29116460; PMID:29120784; PMID:29847215; PMID:30314293; PMID:30886338; PMID:31151650; PMID:31557976; PMID:31890180; Reaxys:2113180; Wikipedia:Methyl_gallate
G
Hmox1
heme oxygenase 1
increases expression
ISO
methyl gallate results in increased expression of HMOX1 mRNA
CTD
PMID:27777014
NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
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Il10
interleukin 10
decreases expression
ISO
methyl gallate results in decreased expression of IL10 protein
CTD
PMID:32112863
NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
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Il12a
interleukin 12A
multiple interactions
ISO
methyl gallate results in increased expression of [IL12A protein binds to IL12B protein]
CTD
PMID:32112863
NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
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Il12b
interleukin 12B
multiple interactions
ISO
methyl gallate results in increased expression of [IL12A protein binds to IL12B protein]
CTD
PMID:32112863
NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
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Nfe2l2
nuclear factor, erythroid 2-like 2
increases expression
ISO
methyl gallate results in increased expression of NFE2L2 protein
CTD
PMID:27777014
NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
G
Tnf
tumor necrosis factor
increases expression
ISO
methyl gallate results in increased expression of TNF protein
CTD
PMID:32112863
NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 Ensembl chr20:5,189,390...5,192,000
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