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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:prednisolone phosphate
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Accession:CHEBI:145705 term browser browse the term
Definition:A synthetic glucocorticoid resulting from the formal condensation of the 21-hydroxy group of prednisolone with one of the hydroxy groups of phosphoric acid. It is a prodrug for prednisolone that is activated in vivo by phosphatases.
Synonyms:exact_synonym: 11beta,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl dihydrogen phosphate
 related_synonym: Formula=C21H29O8P;   InChI=1S/C21H29O8P/c1-19-7-5-13(22)9-12(19)3-4-14-15-6-8-21(25,17(24)11-29-30(26,27)28)20(15,2)10-16(23)18(14)19/h5,7,9,14-16,18,23,25H,3-4,6,8,10-11H2,1-2H3,(H2,26,27,28)/t14-,15-,16-,18+,19-,20-,21-/m0/s1;   InChIKey=JDOZJEUDSLGTLU-VWUMJDOOSA-N;   SMILES=C[C@@]12C[C@@H]([C@]3([C@]([C@]2([H])CC[C@@]1(C(COP(=O)(O)O)=O)O)(CCC=4[C@]3(C)C=CC(C4)=O)[H])[H])O;   prednisolone 21-(dihydrogen phosphate);   prednisolone 21-monophosphate;   prednisolone 21-phosphate
 xref: CAS:302-25-0;   DrugBank:DB14631;   Drug_Central:4451;   PMID:13783671;   PMID:15802017;   PMID:18283332;   PMID:21896328;   PMID:25791805;   PMID:26319748;   PMID:30547315;   PMID:31578578;   PMID:5090826
 cyclic_relationship: is_conjugate_acid_of CHEBI:145706



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  CHEBI ontology 19860
    role 19832
      application 19675
        anti-inflammatory agent 16628
          prednisolone phosphate 0
Path 2
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  CHEBI ontology 19860
    subatomic particle 19858
      composite particle 19858
        hadron 19858
          baryon 19858
            nucleon 19858
              atomic nucleus 19858
                atom 19858
                  main group element atom 19804
                    p-block element atom 19804
                      carbon group element atom 19745
                        carbon atom 19741
                          organic molecular entity 19741
                            heteroorganic entity 19494
                              organochalcogen compound 19257
                                organooxygen compound 19173
                                  carbonyl compound 18897
                                    ketone 17186
                                      oxo steroid 10545
                                        3-oxo steroid 9934
                                          3-oxo-Delta(4) steroid 9175
                                            progesterone 2730
                                              Delta(1)-progesterone 252
                                                prednisolone 241
                                                  prednisolone phosphate 0
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