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ONTOLOGY REPORT - ANNOTATIONS


Term:1-hydroxymidazolam beta-D-glucuronide
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Accession:CHEBI:145334 term browser browse the term
Definition:A beta-D-glucosiduronic acid that is beta-D-glucuronic acid in which the anomeric hydroxyl hydrogen has been replaced by a 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepin-4-yl group. It is the glucuronidated conjugate of the midazolam metabolite, 1-hydroxymidazolam.
Synonyms:exact_synonym: [8-chloro-6-(2-fluorophenyl)-4H-imidazo[1,5-a][1,4]benzodiazepin-1-yl]methyl beta-D-glucopyranosiduronic acid
 related_synonym: 1'-OH MDZ glucuronide;   1-hydroxymethylmidazolam glucuronide;   1-hydroxymidazolam glucuronide;   Formula=C24H21ClFN3O7;   InChI=1S/C24H21ClFN3O7/c25-11-5-6-16-14(7-11)18(13-3-1-2-4-15(13)26)28-9-12-8-27-17(29(12)16)10-35-24-21(32)19(30)20(31)22(36-24)23(33)34/h1-8,19-22,24,30-32H,9-10H2,(H,33,34)/t19-,20-,21+,22-,24+/m0/s1;   InChIKey=ICIUMXQTLQXWGL-QMDPOKHVSA-N;   MDZ-glucuronide;   SMILES=C1(=NCC=2N(C=3C1=CC(=CC3)Cl)C(=NC2)CO[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C(O)=O)O)O)O)C=5C=CC=CC5F
 xref: CAS:81256-81-7 "ChemIDplus"
 xref_mesh: MESH:C061795
 xref: PMCID:PMC2934138 "Europe PMC";   PMID:10519446 "Europe PMC";   PMID:14513773 "Europe PMC";   PMID:1767626 "Europe PMC";   PMID:17998299 "Europe PMC";   PMID:18256203 "Europe PMC";   PMID:18537963 "Europe PMC";   PMID:20713656 "Europe PMC";   PMID:22660604 "Europe PMC";   PMID:2582710 "Europe PMC";   PMID:6691561 "Europe PMC"


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  CHEBI ontology 19748
    role 19695
      biological role 19693
        biochemical role 19191
          apoptosis inducer 10877
            midazolam 27
              1-hydroxymidazolam 2
                1-hydroxymidazolam beta-D-glucuronide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19748
    subatomic particle 19744
      composite particle 19744
        hadron 19744
          baryon 19744
            nucleon 19744
              atomic nucleus 19744
                atom 19744
                  main group element atom 19628
                    p-block element atom 19628
                      carbon group element atom 19522
                        carbon atom 19516
                          organic molecular entity 19516
                            heteroorganic entity 19080
                              organochalcogen compound 18795
                                organooxygen compound 18707
                                  carbohydrates and carbohydrate derivatives 12113
                                    carbohydrate 12113
                                      carbohydrate derivative 11736
                                        glycosyl compound 10792
                                          glycoside 9140
                                            glycosiduronic acid 129
                                              glucosiduronic acid 129
                                                beta-D-glucosiduronic acid 40
                                                  1-hydroxymidazolam beta-D-glucuronide 0
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