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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:antispermatogenic agent
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Accession:CHEBI:145047 term browser browse the term
Definition:An agent that destroy spermatozoa in the male genitalia and block spermatogenesis.
Synonyms:related_synonym: antispermatogenic;   antispermatogenic agents;   antispermatogenics
 xref: PMID:16371305


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gossypol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alas1 5'-aminolevulinate synthase 1 multiple interactions
increases activity
EXP chromium protoporphyrin IX promotes the reaction [Gossypol results in increased activity of ALAS1 protein] CTD PMID:15027808 NCBI chr 8:114,927,704...114,941,038
Ensembl chr 8:114,927,722...114,940,177
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP [Gossypol co-treated with Methyltestosterone co-treated with Ethinyl Estradiol] results in increased expression of BAX mRNA CTD PMID:15451339 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO Gossypol results in increased expression of BBC3 protein CTD PMID:18840529 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
decreases expression
ISO Gossypol analog binds to and affects the activity of BCL2L1 protein
Gossypol results in decreased expression of BCL2L1 protein
CTD PMID:16020667 PMID:18840529 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl2l11 BCL2 like 11 increases expression ISO Gossypol results in increased expression of BCL2L11 protein CTD PMID:18840529 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
increases activity
ISO
EXP
[zoledronic acid co-treated with Gossypol] results in increased activity of CASP3 protein
Gossypol results in increased cleavage of CASP3 protein
[Gossypol co-treated with Methyltestosterone co-treated with Ethinyl Estradiol] results in increased expression of CASP3 mRNA
Gossypol results in increased activity of CASP3 protein
CTD PMID:15451339 PMID:18840529 PMID:19825521 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 multiple interactions
increases activity
ISO [zoledronic acid co-treated with Gossypol] results in increased activity of CASP7 protein
Gossypol results in increased activity of CASP7 protein
CTD PMID:19825521 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp9 caspase 9 increases cleavage
multiple interactions
ISO
EXP
Gossypol results in increased cleavage of CASP9 protein
[Gossypol co-treated with Methyltestosterone co-treated with Ethinyl Estradiol] results in increased expression of CASP9 mRNA
CTD PMID:15451339 PMID:18840529 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression
multiple interactions
ISO Gossypol results in decreased expression of CCL2 mRNA
zoledronic acid promotes the reaction [Gossypol results in decreased expression of CCL2 mRNA]
CTD PMID:19825521 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Cdh2 cadherin 2 decreases expression EXP Gossypol results in decreased expression of CDH2 protein CTD PMID:15082077 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions ISO [zoledronic acid co-treated with Gossypol] results in decreased expression of CXCL1 mRNA CTD PMID:19825521 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO [zoledronic acid co-treated with Gossypol] results in decreased expression of CXCL1 mRNA CTD PMID:19825521 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Ephb4 EPH receptor B4 multiple interactions ISO [zoledronic acid co-treated with Gossypol] results in decreased expression of EPHB4 mRNA CTD PMID:19825521 NCBI chr12:22,393,338...22,418,332
Ensembl chr12:22,393,330...22,417,980
JBrowse link
G Fas Fas cell surface death receptor multiple interactions EXP [Gossypol co-treated with Methyltestosterone co-treated with Ethinyl Estradiol] results in increased expression of FAS mRNA CTD PMID:15451339 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression
multiple interactions
ISO Gossypol results in decreased expression of FGF2 mRNA
zoledronic acid promotes the reaction [Gossypol results in decreased expression of FGF2 mRNA]
CTD PMID:19825521 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 decreases expression
multiple interactions
ISO Gossypol results in decreased expression of FGFR3 mRNA
zoledronic acid promotes the reaction [Gossypol results in decreased expression of FGFR3 mRNA]
CTD PMID:19825521 NCBI chr14:82,272,322...82,287,739
Ensembl chr14:82,273,070...82,287,706
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression EXP Gossypol results in decreased expression of GJA1 protein CTD PMID:15082077 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases activity
EXP chromium protoporphyrin IX inhibits the reaction [Gossypol results in increased activity of HMOX1 protein] CTD PMID:15027808 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hsd17b8 hydroxysteroid (17-beta) dehydrogenase 8 multiple interactions ISO [Gossypol co-treated with NAD] binds to HSD17B8 protein CTD PMID:25526675 NCBI chr20:3,817,212...3,819,316
Ensembl chr20:3,817,179...3,819,235
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein decreases expression
multiple interactions
ISO Gossypol results in decreased expression of ID1 mRNA
zoledronic acid promotes the reaction [Gossypol results in decreased expression of ID1 mRNA]
CTD PMID:19825521 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
JBrowse link
G Lama5 laminin subunit alpha 5 multiple interactions ISO [zoledronic acid co-treated with Gossypol] results in decreased expression of LAMA5 mRNA CTD PMID:19825521 NCBI chr 3:175,553,042...175,601,112
Ensembl chr 3:175,553,045...175,601,127
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression ISO Gossypol results in decreased expression of MCL1 protein CTD PMID:18840529 PMID:20587533 PMID:21750559 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Mdk midkine decreases expression
multiple interactions
ISO Gossypol results in decreased expression of MDK mRNA
zoledronic acid promotes the reaction [Gossypol results in decreased expression of MDK mRNA]
CTD PMID:19825521 NCBI chr 3:80,841,003...80,843,895
Ensembl chr 3:80,841,005...80,842,916
JBrowse link
G Otc ornithine transcarbamylase multiple interactions EXP Gossypol inhibits the reaction [PRL protein results in increased activity of OTC protein]; Gossypol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of OTC protein] CTD PMID:3097147 NCBI chr  X:13,524,804...13,601,074
Ensembl chr  X:13,524,607...13,601,069
JBrowse link
G Pdgfa platelet derived growth factor subunit A multiple interactions ISO [zoledronic acid co-treated with Gossypol] results in decreased expression of PDGFA mRNA CTD PMID:19825521 NCBI chr12:17,734,141...17,756,186
Ensembl chr12:17,734,133...17,755,285
JBrowse link
G Prl prolactin multiple interactions EXP Gossypol inhibits the reaction [PRL protein results in increased activity of OTC protein] CTD PMID:3097147 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Tymp thymidine phosphorylase multiple interactions ISO Gossypol inhibits the reaction [zoledronic acid results in increased expression of TYMP mRNA] CTD PMID:19825521 NCBI chr 7:130,342,481...130,347,845
Ensembl chr 7:130,342,483...130,347,587
JBrowse link
lonidamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation
ISO arsenic trioxide inhibits the reaction [lonidamine results in increased phosphorylation of AKT1 protein]; lonidamine promotes the reaction [Curcumin results in decreased phosphorylation of AKT1 protein] CTD PMID:20605902 PMID:21889928 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Aqp9 aquaporin 9 multiple interactions EXP lonidamine inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]] CTD PMID:12606488 NCBI chr 8:77,559,621...77,599,781
Ensembl chr 8:77,559,624...77,599,781
JBrowse link
G Bax BCL2 associated X, apoptosis regulator affects localization
multiple interactions
ISO lonidamine affects the localization of BAX protein
Curcumin promotes the reaction [lonidamine affects the localization of BAX protein]; lonidamine promotes the reaction [Curcumin affects the localization of BAX protein]
CTD PMID:20605902 PMID:21889928 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO BCL2 protein inhibits the reaction [[arsenic trioxide co-treated with lonidamine] results in increased cleavage of and results in increased activity of CASP8 protein]; BCL2 protein inhibits the reaction [arsenic trioxide promotes the reaction [lonidamine results in increased cleavage of and results in increased activity of CASP9 protein]]; BCL2 protein inhibits the reaction [lonidamine promotes the reaction [arsenic trioxide results in increased cleavage of and results in increased activity of CASP9 protein]] CTD PMID:21889928 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO lonidamine results in decreased expression of BCL2L1 protein CTD PMID:21889928 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bid BH3 interacting domain death agonist increases activity
multiple interactions
ISO lonidamine results in increased activity of BID protein
[arsenic trioxide co-treated with lonidamine] results in increased cleavage of and results in increased activity of BID protein
CTD PMID:20605902 PMID:21889928 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Casp3 caspase 3 multiple interactions ISO [arsenic trioxide co-treated with lonidamine] results in increased cleavage of and results in increased activity of CASP3 protein; [Curcumin co-treated with lonidamine] results in increased cleavage of CASP3 protein CTD PMID:20605902 PMID:21889928 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 multiple interactions ISO [arsenic trioxide co-treated with lonidamine] results in increased cleavage of and results in increased activity of CASP8 protein; BCL2 protein inhibits the reaction [[arsenic trioxide co-treated with lonidamine] results in increased cleavage of and results in increased activity of CASP8 protein] CTD PMID:21889928 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions ISO [Curcumin co-treated with lonidamine] results in increased cleavage of CASP9 protein; arsenic trioxide promotes the reaction [lonidamine results in increased cleavage of and results in increased activity of CASP9 protein]; BCL2 protein inhibits the reaction [arsenic trioxide promotes the reaction [lonidamine results in increased cleavage of and results in increased activity of CASP9 protein]]; BCL2 protein inhibits the reaction [lonidamine promotes the reaction [arsenic trioxide results in increased cleavage of and results in increased activity of CASP9 protein]]; lonidamine promotes the reaction [arsenic trioxide results in increased cleavage of and results in increased activity of CASP9 protein]; lonidamine results in increased cleavage of and results in increased activity of CASP9 protein CTD PMID:20605902 PMID:21889928 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cftr CF transmembrane conductance regulator decreases activity
multiple interactions
ISO
EXP
lonidamine results in decreased activity of CFTR protein
lonidamine inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]]
CTD PMID:12606488 PMID:15634668 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Htra2 HtrA serine peptidase 2 multiple interactions ISO [lonidamine co-treated with arsenic trioxide] affects the localization of HTRA2 protein CTD PMID:21889928 NCBI chr 4:113,883,671...113,886,833
Ensembl chr 4:113,883,670...113,886,994
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO arsenic trioxide inhibits the reaction [lonidamine results in increased phosphorylation of MAPK1 protein] CTD PMID:21889928 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO arsenic trioxide inhibits the reaction [lonidamine results in increased phosphorylation of MAPK3 protein] CTD PMID:21889928 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression ISO lonidamine results in decreased expression of MCL1 protein CTD PMID:21889928 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Rps6 ribosomal protein S6 multiple interactions
increases phosphorylation
ISO arsenic trioxide inhibits the reaction [lonidamine results in increased phosphorylation of RPS6 protein] CTD PMID:21889928 NCBI chr 5:105,197,821...105,200,681
Ensembl chr 5:105,197,857...105,200,148
Ensembl chr 5:105,197,857...105,200,148
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions
increases phosphorylation
ISO arsenic trioxide inhibits the reaction [lonidamine results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21889928 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
JBrowse link
G Stk11 serine/threonine kinase 11 increases phosphorylation ISO lonidamine results in increased phosphorylation of STK11 protein CTD PMID:23041229 NCBI chr 7:12,440,751...12,457,513
Ensembl chr 7:12,440,751...12,457,513
JBrowse link
G Testin testin gene multiple interactions
increases secretion
increases expression
EXP adenosine-3',5'-cyclic phosphorothioate inhibits the reaction [lonidamine results in increased expression of TESTIN mRNA]; Cycloheximide inhibits the reaction [lonidamine results in increased expression of TESTIN mRNA]; Cycloheximide inhibits the reaction [lonidamine results in increased secretion of TESTIN protein]; Dactinomycin inhibits the reaction [lonidamine results in increased expression of TESTIN mRNA]; Dactinomycin inhibits the reaction [lonidamine results in increased secretion of TESTIN protein]; lonidamine inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of TESTIN mRNA]; lonidamine inhibits the reaction [Bucladesine results in decreased expression of TESTIN mRNA]
lonidamine results in increased expression of TESTIN; lonidamine results in increased expression of TESTIN mRNA
CTD PMID:11090432 NCBI chr17:4,194,796...4,225,376
Ensembl chr17:4,212,890...4,225,376
JBrowse link
G Xiap X-linked inhibitor of apoptosis multiple interactions
decreases expression
ISO arsenic trioxide promotes the reaction [lonidamine results in decreased expression of XIAP protein]; Curcumin promotes the reaction [lonidamine results in decreased expression of XIAP protein]; lonidamine promotes the reaction [arsenic trioxide results in decreased expression of XIAP protein]; lonidamine promotes the reaction [Curcumin results in decreased expression of XIAP protein] CTD PMID:20605902 PMID:21889928 NCBI chr  X:128,409,425...128,455,786
Ensembl chr  X:128,409,472...128,453,000
JBrowse link
molinate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions ISO molinate inhibits the reaction [ALDH2 protein results in increased metabolism of propionaldehyde]; molinate metabolite binds to and results in decreased activity of ALDH2 protein; molinate metabolite inhibits the reaction [ALDH2 protein results in increased metabolism of propionaldehyde] CTD PMID:20954713 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Lhb luteinizing hormone subunit beta affects secretion EXP molinate affects the secretion of LHB protein CTD PMID:15601673 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO molinate results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Uba1 ubiquitin-like modifier activating enzyme 1 multiple interactions ISO molinate results in increased activity of and results in increased ubiquitination of UBA1 protein CTD PMID:25714994 NCBI chr  X:1,723,135...1,745,147
Ensembl chr  X:1,723,174...1,741,701
JBrowse link
solasodine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation ISO solasodine results in decreased phosphorylation of AKT1 protein CTD PMID:28283413 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Bche butyrylcholinesterase decreases activity ISO solasodine results in decreased activity of BCHE protein CTD PMID:31152736 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Bsg basigin (Ok blood group) decreases expression ISO solasodine results in decreased expression of BSG mRNA CTD PMID:28283413 NCBI chr 7:12,875,536...12,882,753
Ensembl chr 7:12,875,537...12,882,753
JBrowse link
G Mir21 microRNA 21 decreases expression ISO solasodine results in decreased expression of MIR21 mRNA CTD PMID:28283413 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression ISO solasodine results in decreased expression of MMP2 mRNA CTD PMID:28283413 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression ISO solasodine results in decreased expression of MMP9 mRNA CTD PMID:28283413 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Reck reversion-inducing-cysteine-rich protein with kazal motifs increases expression ISO solasodine results in increased expression of RECK mRNA CTD PMID:28283413 NCBI chr 5:59,348,568...59,415,169
Ensembl chr 5:59,348,639...59,415,135
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO solasodine results in increased expression of TIMP1 mRNA CTD PMID:28283413 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 increases expression ISO solasodine results in increased expression of TIMP2 mRNA CTD PMID:28283413 NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072
JBrowse link
Triptolide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aaas aladin WD repeat nucleoporin increases expression ISO triptolide results in increased expression of AAAS mRNA CTD PMID:32835833 NCBI chr 7:143,937,198...143,956,668
Ensembl chr 7:143,937,199...143,956,668
JBrowse link
G Aadac arylacetamide deacetylase decreases expression ISO triptolide results in decreased expression of AADAC mRNA CTD PMID:32835833 NCBI chr 2:150,146,234...150,157,480
Ensembl chr 2:150,146,234...150,157,480
JBrowse link
G Abca4 ATP binding cassette subfamily A member 4 increases expression ISO triptolide results in increased expression of ABCA4 mRNA CTD PMID:32835833 NCBI chr 2:225,645,539...225,783,288
Ensembl chr 2:225,645,568...225,783,287
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 increases expression
decreases expression
EXP
ISO
triptolide results in increased expression of ABCB11 protein
triptolide results in decreased expression of ABCB11 mRNA
CTD PMID:32519852 PMID:32987112 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases expression
increases expression
decreases response to substance
ISO
EXP
[ABCB1A mutant form co-treated with triptolide] results in increased abundance of Malondialdehyde; ABCB1A mutant form promotes the reaction [triptolide results in decreased expression of BCL2 protein]; ABCB1A mutant form promotes the reaction [triptolide results in increased activity of GPT protein]; ABCB1A mutant form promotes the reaction [triptolide results in increased expression of BAX protein]
triptolide results in decreased expression of ABCB1A protein
triptolide results in increased expression of ABCB1A protein
ABCB1A protein results in decreased susceptibility to triptolide
CTD PMID:26134275 PMID:32519852 PMID:33600922 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B decreases expression
increases expression
EXP
ISO
triptolide results in decreased expression of ABCB1B mRNA
triptolide results in increased expression of ABCB1B mRNA
CTD PMID:32835833 PMID:33600922 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases expression ISO triptolide results in increased expression of ABCC4 mRNA CTD PMID:32835833 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 decreases expression ISO triptolide results in decreased expression of ABCD2 mRNA CTD PMID:32835833 NCBI chr 7:132,294,564...132,343,169
Ensembl chr 7:132,294,562...132,343,169
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression EXP triptolide results in increased expression of ABCG2 protein CTD PMID:32519852 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Abhd2 abhydrolase domain containing 2, acylglycerol lipase increases expression ISO triptolide results in increased expression of ABHD2 mRNA CTD PMID:32835833 NCBI chr 1:140,998,240...141,087,405
Ensembl chr 1:140,998,240...141,087,405
JBrowse link
G Abhd5 abhydrolase domain containing 5, lysophosphatidic acid acyltransferase increases expression ISO triptolide results in increased expression of ABHD5 mRNA CTD PMID:32835833 NCBI chr 8:130,973,222...131,001,448
Ensembl chr 8:130,973,201...131,001,458
JBrowse link
G Abtb2 ankyrin repeat and BTB domain containing 2 increases expression ISO triptolide results in increased expression of ABTB2 mRNA CTD PMID:32835833 NCBI chr 3:93,494,706...93,648,750
Ensembl chr 3:93,495,106...93,647,721
JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B decreases expression EXP triptolide results in decreased expression of ACAA1B protein CTD PMID:32519852 NCBI chr 8:127,836,235...127,845,296 JBrowse link
G Acaca acetyl-CoA carboxylase alpha increases phosphorylation ISO triptolide results in increased phosphorylation of ACACA protein CTD PMID:29723566 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Acacb acetyl-CoA carboxylase beta decreases expression ISO triptolide results in decreased expression of ACACB mRNA CTD PMID:32835833 NCBI chr12:48,127,149...48,238,969
Ensembl chr12:48,127,149...48,238,887
JBrowse link
G Acly ATP citrate lyase decreases expression ISO triptolide results in decreased expression of ACLY mRNA CTD PMID:32835833 NCBI chr10:88,392,248...88,442,845
Ensembl chr10:88,392,248...88,442,845
JBrowse link
G Acot1 acyl-CoA thioesterase 1 decreases expression
increases expression
ISO
EXP
triptolide results in decreased expression of ACOT1 mRNA
triptolide results in increased expression of ACOT1 protein
CTD PMID:31241159 PMID:32519852 NCBI chr 6:107,485,088...107,493,082
Ensembl chr 6:107,485,249...107,493,798
JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression ISO triptolide results in increased expression of ACOT2 mRNA CTD PMID:32835833 NCBI chr 6:107,460,596...107,468,324
Ensembl chr 6:107,460,668...107,467,487
JBrowse link
G Acot3 acyl-CoA thioesterase 3 increases expression ISO triptolide results in increased expression of ACOT3 mRNA CTD PMID:32835833 NCBI chr 6:107,531,508...107,537,446
Ensembl chr 6:107,531,528...107,536,789
JBrowse link
G Acot9 acyl-CoA thioesterase 9 increases expression ISO triptolide results in increased expression of ACOT9 mRNA CTD PMID:32835833 NCBI chr  X:43,543,069...43,592,200
Ensembl chr  X:43,543,070...43,592,200
JBrowse link
G Acox2 acyl-CoA oxidase 2 decreases expression
increases expression
ISO
EXP
triptolide results in decreased expression of ACOX2 mRNA
triptolide results in increased expression of ACOX2 protein
CTD PMID:31241159 PMID:32519852 NCBI chr15:18,449,304...18,481,472
Ensembl chr15:18,451,144...18,481,470
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 decreases expression ISO triptolide results in decreased expression of ACSL5 mRNA CTD PMID:32835833 NCBI chr 1:276,240,703...276,290,012
Ensembl chr 1:276,240,703...276,290,008
JBrowse link
G Acsm1 acyl-CoA synthetase medium-chain family member 1 decreases expression EXP triptolide results in decreased expression of ACSM1 protein CTD PMID:32519852 NCBI chr 1:189,359,374...189,395,277
Ensembl chr 1:189,289,957...189,395,276
JBrowse link
G Acsm2 acyl-CoA synthetase medium-chain family member 2 decreases expression EXP triptolide results in decreased expression of ACSM2 protein CTD PMID:32519852 NCBI chr 1:189,289,957...189,329,007
Ensembl chr 1:189,289,957...189,395,276
JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 decreases expression ISO triptolide results in decreased expression of ACSS2 mRNA CTD PMID:32835833 NCBI chr 3:151,032,925...151,075,856
Ensembl chr 3:151,032,952...151,075,856
JBrowse link
G Actb actin, beta decreases expression EXP triptolide results in decreased expression of ACTB mRNA; triptolide results in decreased expression of ACTB protein CTD PMID:27554044 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Ada adenosine deaminase increases expression EXP triptolide results in increased expression of ADA protein CTD PMID:32519852 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947
JBrowse link
G Adam11 ADAM metallopeptidase domain 11 decreases expression ISO triptolide results in decreased expression of ADAM11 mRNA CTD PMID:32835833 NCBI chr10:90,731,260...90,749,221
Ensembl chr10:90,731,148...90,749,217
JBrowse link
G Adam1a ADAM metallopeptidase domain 1a increases expression ISO triptolide results in increased expression of ADAM1A mRNA CTD PMID:32835833 NCBI chr12:40,533,731...40,536,632
Ensembl chr12:40,533,632...40,536,620
JBrowse link
G Adam2 ADAM metallopeptidase domain 2 increases expression ISO triptolide results in increased expression of ADAM2 mRNA CTD PMID:32835833 NCBI chr15:42,708,536...42,751,281
Ensembl chr15:42,708,387...42,751,330
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 increases expression ISO triptolide results in increased expression of ADAMTS1 mRNA CTD PMID:32835833 NCBI chr11:25,342,119...25,350,938
Ensembl chr11:25,342,126...25,350,974
JBrowse link
G Adgrf1 adhesion G protein-coupled receptor F1 decreases expression ISO triptolide results in decreased expression of ADGRF1 mRNA CTD PMID:32835833 NCBI chr 9:20,343,730...20,378,686 JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) decreases expression EXP triptolide results in decreased expression of ADH1 mRNA CTD PMID:23639586 NCBI chr 2:243,550,655...243,562,243
Ensembl chr 2:243,550,627...243,687,857
JBrowse link
G Adpgk ADP-dependent glucokinase increases expression EXP
ISO
triptolide results in increased expression of ADPGK mRNA CTD PMID:23639586 PMID:32835833 NCBI chr 8:64,088,871...64,116,832
Ensembl chr 8:64,088,913...64,116,832
JBrowse link
G Aen apoptosis enhancing nuclease increases expression ISO triptolide results in increased expression of AEN mRNA CTD PMID:32835833 NCBI chr 1:140,584,328...140,593,749
Ensembl chr 1:140,584,380...140,593,745
JBrowse link
G Afm afamin increases expression
decreases expression
EXP
ISO
triptolide results in increased expression of AFM protein
triptolide results in decreased expression of AFM mRNA
CTD PMID:32519852 PMID:32835833 NCBI chr14:19,078,678...19,132,212
Ensembl chr14:19,078,680...19,132,208
JBrowse link
G Afmid arylformamidase decreases expression ISO triptolide results in decreased expression of AFMID mRNA CTD PMID:32835833 NCBI chr10:106,828,963...106,844,314
Ensembl chr10:106,828,981...106,844,314
JBrowse link
G Agpat5 1-acylglycerol-3-phosphate O-acyltransferase 5 increases expression ISO triptolide results in increased expression of AGPAT5 mRNA CTD PMID:32835833 NCBI chr16:75,812,837...75,855,996
Ensembl chr16:75,812,997...75,855,745
JBrowse link
G Agps alkylglycerone phosphate synthase increases expression EXP triptolide results in increased expression of AGPS protein CTD PMID:32519852 NCBI chr 3:62,648,352...62,749,250
Ensembl chr 3:62,648,447...62,749,153
JBrowse link
G Ahcy adenosylhomocysteinase decreases expression ISO triptolide results in decreased expression of AHCY mRNA CTD PMID:32835833 NCBI chr 3:150,587,833...150,603,057
Ensembl chr 3:150,587,833...150,603,082
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 decreases expression ISO triptolide results in decreased expression of AIFM1 protein CTD PMID:26990902 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases expression EXP triptolide results in increased expression of AKR1B1 protein CTD PMID:32519852 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 decreases expression EXP triptolide results in decreased expression of AKR1B10 protein CTD PMID:32519852 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akr1b8 aldo-keto reductase family 1, member B8 increases expression EXP triptolide results in increased expression of AKR1B8 protein CTD PMID:32519852 NCBI chr 4:61,772,064...61,784,637
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 decreases expression ISO triptolide results in decreased expression of AKR1C6 mRNA CTD PMID:32835833 NCBI chr17:69,441,253...69,460,334
Ensembl chr17:69,441,223...69,460,321
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 increases expression EXP triptolide results in increased expression of AKR7A2 protein CTD PMID:32519852 NCBI chr 5:157,759,448...157,768,473
Ensembl chr 5:157,759,416...157,768,471
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation
EXP
ISO
triptolide inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of AKT1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [triptolide results in decreased phosphorylation of AKT1 protein]
CTD PMID:21717513 PMID:32061799 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt2 AKT serine/threonine kinase 2 decreases expression EXP triptolide results in decreased expression of AKT2 mRNA CTD PMID:23639586 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162
JBrowse link
G Alb albumin increases expression EXP triptolide results in increased expression of ALB protein CTD PMID:32519852 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 decreases expression ISO triptolide results in decreased expression of ALDH1L1 mRNA CTD PMID:32835833 NCBI chr 4:123,516,553...123,564,067
Ensembl chr 4:123,516,788...123,557,501
JBrowse link
G Aldob aldolase, fructose-bisphosphate B decreases expression EXP
ISO
triptolide results in decreased expression of ALDOB mRNA CTD PMID:23639586 PMID:32835833 NCBI chr 5:64,805,772...64,818,813
Ensembl chr 5:64,805,773...64,818,824
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C decreases expression ISO triptolide results in decreased expression of ALDOC mRNA CTD PMID:32835833 NCBI chr10:65,586,504...65,590,093
Ensembl chr10:65,586,504...65,590,126
JBrowse link
G Amacr alpha-methylacyl-CoA racemase affects expression EXP triptolide affects the expression of AMACR protein CTD PMID:32519852 NCBI chr 2:60,949,276...60,961,342
Ensembl chr 2:60,949,256...60,961,326
JBrowse link
G Ambp alpha-1-microglobulin/bikunin precursor increases expression EXP triptolide results in increased expression of AMBP protein CTD PMID:32519852 NCBI chr 5:78,975,690...78,986,021
Ensembl chr 5:78,975,678...78,985,990
JBrowse link
G Amh anti-Mullerian hormone increases expression ISO triptolide results in increased expression of AMH mRNA CTD PMID:32835833 NCBI chr 7:11,775,155...11,777,503
Ensembl chr 7:11,775,155...11,777,503
JBrowse link
G Ankmy1 ankyrin repeat and MYND domain containing 1 increases expression ISO triptolide results in increased expression of ANKMY1 mRNA CTD PMID:32835833 NCBI chr 9:100,026,435...100,074,274
Ensembl chr 9:100,038,846...100,070,650
JBrowse link
G Ankrd13a ankyrin repeat domain 13a increases expression ISO triptolide results in increased expression of ANKRD13A mRNA CTD PMID:32835833 NCBI chr12:47,558,587...47,588,486
Ensembl chr12:47,558,590...47,588,335
JBrowse link
G Ano6 anoctamin 6 increases expression EXP triptolide results in increased expression of ANO6 protein CTD PMID:32519852 NCBI chr 7:137,142,063...137,335,208
Ensembl chr 7:137,142,170...137,335,208
JBrowse link
G Anp32e acidic nuclear phosphoprotein 32 family member E increases expression EXP triptolide results in increased expression of ANP32E protein CTD PMID:32519852 NCBI chr 2:198,040,573...198,057,005
Ensembl chr 2:198,040,536...198,057,003
JBrowse link
G Anpep alanyl aminopeptidase, membrane affects expression EXP triptolide affects the expression of ANPEP protein CTD PMID:32519852 NCBI chr 1:141,561,364...141,604,249
Ensembl chr 1:141,561,334...141,604,273
JBrowse link
G Anxa13 annexin A13 increases expression EXP triptolide results in increased expression of ANXA13 protein CTD PMID:32519852 NCBI chr 7:98,217,642...98,270,442
Ensembl chr 7:98,217,642...98,270,110
JBrowse link
G Anxa9 annexin A9 increases expression ISO triptolide results in increased expression of ANXA9 mRNA CTD PMID:32835833 NCBI chr 2:196,470,318...196,481,568
Ensembl chr 2:196,470,858...196,479,770
JBrowse link
G Aoc2-ps1 amine oxidase, copper containing 2, pseudogene 1 increases expression ISO triptolide results in increased expression of AOC2 mRNA CTD PMID:32835833 NCBI chr10:89,245,590...89,247,056 JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression
multiple interactions
ISO
EXP
triptolide results in increased expression of APAF1 protein
NFE2L2 protein inhibits the reaction [triptolide results in increased expression of APAF1 protein]
CTD PMID:25169008 PMID:26990902 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Apex2 apurinic/apyrimidinic endodeoxyribonuclease 2 affects expression ISO triptolide affects the expression of APEX2 mRNA CTD PMID:32835833 NCBI chr  X:23,146,085...23,166,676
Ensembl chr  X:23,146,085...23,166,675
JBrowse link
G Apoa1 apolipoprotein A1 increases expression EXP triptolide results in increased expression of APOA1 protein CTD PMID:32519852 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Aqp1 aquaporin 1 increases expression EXP triptolide results in increased expression of AQP1 protein CTD PMID:32519852 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Aqp2 aquaporin 2 increases expression EXP triptolide results in increased expression of AQP2 protein CTD PMID:32519852 NCBI chr 7:141,237,802...141,242,837
Ensembl chr 7:141,237,768...141,245,165
JBrowse link
G Aqp4 aquaporin 4 decreases expression ISO triptolide results in decreased expression of AQP4 mRNA CTD PMID:32835833 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
JBrowse link
G Aqp8 aquaporin 8 decreases expression ISO triptolide results in decreased expression of AQP8 mRNA CTD PMID:32835833 NCBI chr 1:193,424,818...193,430,665
Ensembl chr 1:193,424,812...193,430,676
JBrowse link
G Arc activity-regulated cytoskeleton-associated protein increases expression ISO triptolide results in increased expression of ARC mRNA CTD PMID:32835833 NCBI chr 7:115,907,097...115,911,059
Ensembl chr 7:115,907,097...115,910,541
JBrowse link
G Arglu1 arginine and glutamate rich 1 increases expression EXP triptolide results in increased expression of ARGLU1 protein CTD PMID:32519852 NCBI chr16:86,600,877...86,625,084
Ensembl chr16:86,600,877...86,625,083
JBrowse link
G Arhgef16 Rho guanine nucleotide exchange factor 16 decreases expression ISO triptolide results in decreased expression of ARHGEF16 mRNA CTD PMID:32835833 NCBI chr 5:171,626,450...171,649,124
Ensembl chr 5:171,624,796...171,648,563
JBrowse link
G Arhgef37 Rho guanine nucleotide exchange factor 37 decreases expression ISO triptolide results in decreased expression of ARHGEF37 mRNA CTD PMID:32835833 NCBI chr18:56,817,986...56,871,159
Ensembl chr18:56,817,988...56,870,839
JBrowse link
G Arid1a AT-rich interaction domain 1A increases expression ISO triptolide results in increased expression of ARID1A mRNA CTD PMID:32835833 NCBI chr 5:151,904,687...151,977,973
Ensembl chr 5:151,904,684...151,977,636
JBrowse link
G Arid5a AT-rich interaction domain 5A increases expression ISO triptolide results in increased expression of ARID5A mRNA CTD PMID:32835833 NCBI chr 9:42,871,907...42,886,725
Ensembl chr 9:42,871,950...42,884,855
JBrowse link
G Arl8b ADP-ribosylation factor like GTPase 8B decreases expression EXP triptolide results in decreased expression of ARL8B protein CTD PMID:32519852 NCBI chr 4:140,837,745...140,881,866
Ensembl chr 4:140,837,745...140,881,865
JBrowse link
G Armc9 armadillo repeat containing 9 increases expression EXP triptolide results in increased expression of ARMC9 protein CTD PMID:32519852 NCBI chr 9:93,172,718...93,299,119
Ensembl chr 9:93,172,673...93,296,750
JBrowse link
G Arrb1 arrestin, beta 1 increases expression EXP triptolide results in increased expression of ARRB1 protein CTD PMID:32519852 NCBI chr 1:164,502,099...164,573,947
Ensembl chr 1:164,502,389...164,593,139
JBrowse link
G Ascl3 achaete-scute family bHLH transcription factor 3 increases expression ISO triptolide results in increased expression of ASCL3 mRNA CTD PMID:32835833 NCBI chr 1:174,351,413...174,355,590 JBrowse link
G Asgr1 asialoglycoprotein receptor 1 decreases expression ISO triptolide results in decreased expression of ASGR1 mRNA CTD PMID:32835833 NCBI chr10:56,662,188...56,666,086
Ensembl chr10:56,662,242...56,666,086
JBrowse link
G Asl argininosuccinate lyase decreases expression ISO triptolide results in decreased expression of ASL mRNA CTD PMID:32835833 NCBI chr12:30,160,922...30,178,348
Ensembl chr12:30,165,694...30,178,341
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression EXP triptolide results in increased expression of ASNS protein CTD PMID:32519852 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Ass1 argininosuccinate synthase 1 decreases expression EXP
ISO
triptolide results in decreased expression of ASS1 protein
triptolide results in decreased expression of ASS1 mRNA
CTD PMID:32519852 PMID:32835833 NCBI chr 3:10,327,411...10,375,847
Ensembl chr 3:10,327,414...10,375,826
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO triptolide results in increased expression of ATF3 mRNA CTD PMID:32835833 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atf4 activating transcription factor 4 decreases expression EXP triptolide results in decreased expression of ATF4 mRNA CTD PMID:23639586 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atf5 activating transcription factor 5 decreases expression ISO triptolide results in decreased expression of ATF5 mRNA CTD PMID:32835833 NCBI chr 1:100,807,821...100,812,410
Ensembl chr 1:100,808,241...100,810,522
JBrowse link
G Atf6 activating transcription factor 6 decreases expression ISO triptolide results in decreased expression of ATF6 protein CTD PMID:26990902 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443
JBrowse link
G Atf6b activating transcription factor 6 beta decreases expression ISO triptolide results in decreased expression of ATF6B protein CTD PMID:26990902 NCBI chr20:4,414,283...4,422,283
Ensembl chr20:4,414,276...4,422,283
JBrowse link
G Atg12 autophagy related 12 increases expression ISO triptolide results in increased expression of ATG12 protein CTD PMID:26990902 NCBI chr18:40,721,799...40,732,143
Ensembl chr18:40,721,800...40,732,126
JBrowse link
G Atg5 autophagy related 5 increases expression ISO triptolide results in increased expression of ATG5 protein CTD PMID:26990902 NCBI chr20:49,301,783...49,393,147
Ensembl chr20:49,318,308...49,393,140
JBrowse link
G Atg7 autophagy related 7 increases expression ISO triptolide results in increased expression of ATG7 protein CTD PMID:26990902 NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124
JBrowse link
G Atp11a ATPase phospholipid transporting 11A increases expression EXP triptolide results in increased expression of ATP11A protein CTD PMID:32519852 NCBI chr16:81,990,340...82,100,222
Ensembl chr16:81,990,340...82,100,222
JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon decreases expression EXP triptolide results in decreased expression of ATP5E protein CTD PMID:32519852 NCBI chr 3:172,563,105...172,566,007
Ensembl chr 3:172,563,105...172,566,010
JBrowse link
G Atp5mc3 ATP synthase membrane subunit c locus 3 increases expression EXP triptolide results in increased expression of ATP5G3 protein CTD PMID:32519852 NCBI chr 3:60,811,218...60,813,903
Ensembl chr 3:60,811,210...60,813,869
JBrowse link
G Atp5me ATP synthase membrane subunit e increases expression EXP triptolide results in increased expression of ATP5I protein CTD PMID:32519852 NCBI chr14:2,325,308...2,326,436
Ensembl chr14:2,325,308...2,326,436
JBrowse link
G Atp5mj ATP synthase membrane subunit j decreases expression EXP triptolide results in decreased expression of ATP5MJ protein CTD PMID:32519852
G Atp6v0a1 ATPase H+ transporting V0 subunit a1 increases expression EXP triptolide results in increased expression of ATP6V0A1 protein CTD PMID:32519852 NCBI chr10:88,914,264...88,967,736
Ensembl chr10:88,914,276...88,967,748
JBrowse link
G Atp6v0a4 ATPase H+ transporting V0 subunit a4 increases expression EXP triptolide results in increased expression of ATP6V0A4 protein CTD PMID:32519852 NCBI chr 4:65,736,585...65,821,916
Ensembl chr 4:65,736,585...65,818,521
JBrowse link
G Atp6v0c ATPase H+ transporting V0 subunit C increases expression EXP triptolide results in increased expression of ATP6V0C protein CTD PMID:32519852 NCBI chr10:13,537,031...13,543,407
Ensembl chr10:13,537,033...13,542,077
JBrowse link
G Atp6v0d1 ATPase H+ transporting V0 subunit D1 increases expression EXP triptolide results in increased expression of ATP6V0D1 protein CTD PMID:32519852 NCBI chr19:37,481,782...37,525,762
Ensembl chr19:37,481,782...37,525,762
JBrowse link
G B4galt1 beta-1,4-galactosyltransferase 1 increases expression ISO triptolide results in increased expression of B4GALT1 mRNA CTD PMID:32835833 NCBI chr 5:57,121,768...57,168,610
Ensembl chr 5:57,121,769...57,168,610
JBrowse link
G Bag3 BAG cochaperone 3 increases expression ISO triptolide results in increased expression of BAG3 mRNA CTD PMID:32835833 NCBI chr 1:199,941,258...199,965,191
Ensembl chr 1:199,941,161...199,965,191
JBrowse link
G Baiap3 BAI1-associated protein 3 increases expression ISO triptolide results in increased expression of BAIAP3 mRNA CTD PMID:32835833 NCBI chr10:14,601,133...14,613,881
Ensembl chr10:14,599,197...14,613,878
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions
increases expression
EXP
ISO
pifithrin inhibits the reaction [triptolide results in increased expression of BAK1 protein]
TRP53 gene mutant form inhibits the reaction [triptolide results in increased expression of BAK1 protein]
CTD PMID:30009776 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
affects expression
EXP
ISO
NFE2L2 protein inhibits the reaction [triptolide results in increased expression of BAX protein]; pifithrin inhibits the reaction [triptolide results in increased expression of BAX protein]; Quercetin inhibits the reaction [triptolide affects the expression of BAX protein]; Val-Pro-Met-Leu-Lys inhibits the reaction [triptolide results in increased expression of BAX protein]
triptolide results in increased expression of BAX mRNA; triptolide results in increased expression of BAX protein
10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [triptolide results in increased expression of BAX protein]; ABCB1A mutant form promotes the reaction [triptolide results in increased expression of BAX protein]; tariquidar promotes the reaction [triptolide results in increased expression of BAX protein]; TRP53 gene mutant form inhibits the reaction [triptolide results in increased expression of BAX protein]
CTD PMID:25169008 PMID:26134275 PMID:26277538 PMID:26990902 PMID:30009776 PMID:30836114 PMID:32835833 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression EXP triptolide results in increased expression of BBC3 protein CTD PMID:30009776 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
increases expression
multiple interactions
affects expression
EXP
ISO
triptolide results in decreased expression of BCL2 protein
triptolide results in increased expression of BCL2 protein
ABCB1A mutant form promotes the reaction [triptolide results in decreased expression of BCL2 protein]; NOTCH1 protein modified form inhibits the reaction [triptolide results in decreased expression of BCL2 protein]; tariquidar promotes the reaction [triptolide results in decreased expression of BCL2 protein]; TRP53 gene mutant form inhibits the reaction [triptolide results in decreased expression of BCL2 protein]
triptolide affects the expression of BCL2 protein
Lithium Chloride inhibits the reaction [triptolide results in decreased expression of BCL2 protein]; NFE2L2 protein inhibits the reaction [triptolide results in decreased expression of BCL2 protein]; pifithrin inhibits the reaction [triptolide results in decreased expression of BCL2 protein]; Quercetin inhibits the reaction [triptolide affects the expression of BCL2 protein]; Val-Pro-Met-Leu-Lys inhibits the reaction [triptolide results in decreased expression of BCL2 protein]
CTD PMID:25169008 PMID:26134275 PMID:26277538 PMID:26990902 PMID:30009776 PMID:30394310 PMID:30836114 PMID:30926361 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression
decreases expression
multiple interactions
ISO
EXP
triptolide results in increased expression of BCL2L1 protein
triptolide results in decreased expression of BCL2L1 protein
TRP53 gene mutant form inhibits the reaction [triptolide results in decreased expression of BCL2L1 protein]
pifithrin inhibits the reaction [triptolide results in decreased expression of BCL2L1 protein]
CTD PMID:26990902 PMID:30009776 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl2l14 BCL2 like 14 increases expression ISO triptolide results in increased expression of BCL2L14 mRNA CTD PMID:32835833 NCBI chr 4:168,139,964...168,183,726
Ensembl chr 4:168,142,271...168,183,096
JBrowse link
G Bdh2 3-hydroxybutyrate dehydrogenase 2 decreases expression ISO triptolide results in decreased expression of BDH2 mRNA CTD PMID:32835833 NCBI chr 2:240,461,505...240,482,149
Ensembl chr 2:240,461,505...240,482,145
JBrowse link
G Becn1 beclin 1 increases expression ISO triptolide results in increased expression of BECN1 protein CTD PMID:26990902 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bfsp1 beaded filament structural protein 1 increases expression ISO triptolide results in increased expression of BFSP1 mRNA CTD PMID:32835833 NCBI chr 3:137,935,345...137,992,652
Ensembl chr 3:137,935,345...137,969,658
JBrowse link
G Bhlhb9 basic helix-loop-helix family member B9 decreases expression ISO triptolide results in decreased expression of BHLHB9 mRNA CTD PMID:32835833 NCBI chr  X:106,359,981...106,393,457
Ensembl chr  X:106,390,759...106,393,459
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 decreases expression ISO triptolide results in decreased expression of BHLHE40 mRNA CTD PMID:32835833 NCBI chr 4:140,703,619...140,709,319
Ensembl chr 4:140,703,619...140,709,319
JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO triptolide results in increased expression of BID protein CTD PMID:26990902 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO triptolide results in decreased expression of BIRC3 mRNA CTD PMID:15972136 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Blvra biliverdin reductase A affects expression EXP triptolide affects the expression of BLVRA protein CTD PMID:32519852 NCBI chr 3:119,552,550...119,577,796
Ensembl chr 3:119,561,290...119,577,806
JBrowse link
G Bmf Bcl2 modifying factor decreases expression ISO triptolide results in decreased expression of BMF mRNA CTD PMID:32835833 NCBI chr 3:110,303,515...110,324,125
Ensembl chr 3:110,306,067...110,324,084
JBrowse link
G Bop1 BOP1 ribosomal biogenesis factor increases expression ISO triptolide results in increased expression of BOP1 mRNA CTD PMID:32835833 NCBI chr 7:117,514,529...117,538,342
Ensembl chr 7:117,514,533...117,538,342
JBrowse link
G Bsnd barttin CLCNK type accessory subunit beta decreases expression EXP triptolide results in decreased expression of BSND protein CTD PMID:32519852 NCBI chr 5:126,071,849...126,080,647
Ensembl chr 5:126,071,846...126,080,698
JBrowse link
G Bst2 bone marrow stromal cell antigen 2 increases expression EXP triptolide results in increased expression of BST2 protein CTD PMID:32519852 NCBI chr16:19,938,781...19,942,353
Ensembl chr16:19,938,784...19,942,353
JBrowse link
G Btaf1 B-TFIID TATA-box binding protein associated factor 1 increases expression ISO triptolide results in increased expression of BTAF1 mRNA CTD PMID:32835833 NCBI chr 1:255,564,247...255,654,932
Ensembl chr 1:255,564,409...255,654,932
JBrowse link
G Btbd10 BTB domain containing 10 increases expression ISO triptolide results in increased expression of BTBD10 mRNA CTD PMID:32835833 NCBI chr 1:178,138,562...178,196,551
Ensembl chr 1:178,138,565...178,196,294
JBrowse link
G Btg3 BTG anti-proliferation factor 3 increases expression ISO triptolide results in increased expression of BTG3 mRNA CTD PMID:32835833 NCBI chr11:16,873,642...16,889,100
Ensembl chr11:16,873,646...16,889,201
JBrowse link
G Btnl9 butyrophilin-like 9 increases expression ISO triptolide results in increased expression of BTNL9 mRNA CTD PMID:32835833 NCBI chr10:34,424,830...34,443,749
Ensembl chr10:34,425,069...34,439,470
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase decreases expression
increases expression
EXP triptolide results in decreased expression of BUB1 mRNA
triptolide results in increased expression of BUB1 mRNA
CTD PMID:23639586 NCBI chr 3:120,373,604...120,404,910
Ensembl chr 3:120,373,604...120,404,910
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B increases expression EXP triptolide results in increased expression of BUB1B mRNA CTD PMID:23639586 NCBI chr 3:110,367,949...110,420,471
Ensembl chr 3:110,367,939...110,420,458
JBrowse link
G Bub3 BUB3 mitotic checkpoint protein decreases expression EXP triptolide results in decreased expression of BUB3 mRNA CTD PMID:23639586 NCBI chr 1:203,526,853...203,537,459
Ensembl chr 1:203,524,426...203,557,337
JBrowse link
G C1qa complement C1q A chain increases expression EXP triptolide results in increased expression of C1QA protein CTD PMID:32519852 NCBI chr 5:155,261,254...155,264,101
Ensembl chr 5:155,261,250...155,264,143
JBrowse link
G C3 complement C3 increases expression EXP triptolide results in increased expression of C3 protein CTD PMID:32519852 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G C4a complement C4A increases expression EXP triptolide results in increased expression of C4A protein CTD PMID:32519852 NCBI chr20:2,651,599...2,678,183
Ensembl chr20:2,651,599...2,678,141
JBrowse link
G Ca14 carbonic anhydrase 14 decreases expression ISO triptolide results in decreased expression of CAR14 mRNA CTD PMID:32835833 NCBI chr 2:198,010,142...198,017,635
Ensembl chr 2:198,010,349...198,016,898
JBrowse link
G Ca3 carbonic anhydrase 3 increases expression EXP triptolide results in increased expression of CA3 protein CTD PMID:32519852 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410
JBrowse link
G Ca9 carbonic anhydrase 9 multiple interactions ISO triptolide inhibits the reaction [cobaltous chloride results in increased expression of CA9 protein] CTD PMID:24842335 NCBI chr 5:59,008,277...59,015,535
Ensembl chr 5:59,008,933...59,015,528
JBrowse link
G Cabcoco1 ciliary associated calcium binding coiled-coil 1 decreases expression ISO triptolide results in decreased expression of CABCOCO1 mRNA CTD PMID:32835833 NCBI chr20:21,316,770...21,426,036
Ensembl chr20:21,316,826...21,426,034
JBrowse link
G Cabyr calcium binding tyrosine phosphorylation regulated increases expression ISO triptolide results in increased expression of CABYR mRNA CTD PMID:32835833 NCBI chr18:4,082,175...4,096,650
Ensembl chr18:4,084,228...4,095,936
JBrowse link
G Cald1 caldesmon 1 decreases expression EXP triptolide results in decreased expression of CALD1 protein CTD PMID:32519852 NCBI chr 4:62,103,948...62,291,375
Ensembl chr 4:62,220,736...62,291,489
JBrowse link
G Camta2 calmodulin binding transcription activator 2 increases expression ISO triptolide results in increased expression of CAMTA2 mRNA CTD PMID:32835833 NCBI chr10:57,291,192...57,309,638
Ensembl chr10:57,291,192...57,309,298
JBrowse link
G Capg capping actin protein, gelsolin like increases expression EXP triptolide results in increased expression of CAPG protein CTD PMID:32519852 NCBI chr 4:100,395,693...100,419,447
Ensembl chr 4:100,407,658...100,419,446
JBrowse link
G Capn1 calpain 1 increases expression ISO triptolide results in increased expression of CAPN1 protein CTD PMID:26990902 NCBI chr 1:221,346,081...221,370,965
Ensembl chr 1:221,346,066...221,370,322
JBrowse link
G Capn2 calpain 2 increases expression ISO triptolide results in increased expression of CAPN2 protein CTD PMID:26990902 NCBI chr13:100,878,649...100,928,811
Ensembl chr13:100,878,650...100,928,811
JBrowse link
G Caps calcyphosine increases expression ISO triptolide results in increased expression of TNFRSF23 mRNA CTD PMID:32835833
G Car1 carbonic anhydrase 1 increases expression EXP triptolide results in increased expression of CA1 protein CTD PMID:32519852 NCBI chr 2:88,185,204...88,227,486
Ensembl chr 2:88,217,188...88,227,479
JBrowse link
G Carf calcium responsive transcription factor increases expression ISO triptolide results in increased expression of CARF mRNA CTD PMID:32835833 NCBI chr 9:66,878,526...66,928,658
Ensembl chr 9:66,888,393...66,926,377
JBrowse link
G Carhsp1 calcium regulated heat stable protein 1 decreases expression EXP triptolide results in decreased expression of CARHSP1 protein CTD PMID:32519852 NCBI chr10:7,041,510...7,055,107
Ensembl chr10:7,041,510...7,055,101
JBrowse link
G Carmil1 capping protein regulator and myosin 1 linker 1 decreases expression ISO triptolide results in decreased expression of LRRC16A mRNA CTD PMID:32835833 NCBI chr17:43,050,282...43,339,403
Ensembl chr17:43,050,789...43,339,403
JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 increases expression ISO triptolide results in increased expression of RLTPR mRNA CTD PMID:32835833 NCBI chr19:37,652,383...37,665,333
Ensembl chr19:37,652,969...37,668,019
JBrowse link
G Casp12 caspase 12 increases expression ISO triptolide results in increased expression of CASP12 protein CTD PMID:26990902 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
increases expression
increases activity
ISO
EXP
triptolide results in increased activity of and results in increased cleavage of CASP3 protein
triptolide results in increased cleavage of CASP3 protein
triptolide results in increased expression of CASP3 protein modified form
10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]; [triptolide co-treated with Lipopolysaccharides] results in increased expression of CASP3 protein modified form; benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane inhibits the reaction [[triptolide co-treated with Lipopolysaccharides] results in increased expression of CASP3 protein modified form]; NOTCH1 protein modified form inhibits the reaction [triptolide results in increased expression of CASP3 protein modified form]; triptolide results in increased expression of and results in increased activity of CASP3 protein; TRP53 gene mutant form inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]
triptolide results in increased activity of CASP3 protein
benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]; Lithium Chloride inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]; NFE2L2 protein inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]; pifithrin inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]; Quercetin inhibits the reaction [triptolide results in increased activity of CASP3 protein]; Val-Pro-Met-Leu-Lys inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]
CTD PMID:12533674 PMID:15972136 PMID:19233258 PMID:21640813 PMID:23639586 PMID:25169008 PMID:26277538 PMID:26990902 PMID:30009776 PMID:30394310 PMID:30633930 PMID:30836114 PMID:30926361 PMID:32835833 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 increases activity
increases expression
ISO
EXP
triptolide results in increased activity of CASP7 protein
triptolide results in increased expression of CASP7 protein
CTD PMID:21640813 PMID:32519852 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 multiple interactions ISO [triptolide co-treated with Lipopolysaccharides] results in increased expression of CASP8 protein modified form; triptolide results in increased expression of and results in increased activity of CASP8 protein CTD PMID:26990902 PMID:30633930 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage
increases expression
increases activity
EXP
ISO
pifithrin inhibits the reaction [triptolide results in increased expression of CASP9 protein modified form]; Quercetin inhibits the reaction [triptolide results in increased activity of CASP9 protein]; Val-Pro-Met-Leu-Lys inhibits the reaction [triptolide results in increased expression of CASP9 protein modified form]
triptolide results in increased cleavage of CASP9 protein
triptolide results in increased expression of and results in increased activity of CASP9 protein; TRP53 gene mutant form inhibits the reaction [triptolide results in increased expression of CASP9 protein modified form]
CTD PMID:26277538 PMID:26990902 PMID:30009776 PMID:32835833 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Castor1 cytosolic arginine sensor for mTORC1 subunit 1 increases expression EXP triptolide results in increased expression of CASTOR1 protein CTD PMID:32519852 NCBI chr14:84,447,552...84,457,396
Ensembl chr14:84,447,885...84,452,367
JBrowse link
G Cav1 caveolin 1 increases expression EXP triptolide results in increased expression of CAV1 protein CTD PMID:32519852 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Cbarp CACN subunit beta associated regulatory protein increases expression ISO triptolide results in increased expression of CBARP mRNA CTD PMID:32835833 NCBI chr 7:12,433,422...12,441,048
Ensembl chr 7:12,433,933...12,441,048
JBrowse link
G Cblc Cbl proto-oncogene C decreases expression EXP triptolide results in decreased expression of CBLC mRNA CTD PMID:23639586 NCBI chr 1:80,699,321...80,716,146
Ensembl chr 1:80,699,323...80,716,146
JBrowse link
G Cbr3 carbonyl reductase 3 increases expression ISO triptolide results in increased expression of CBR3 mRNA CTD PMID:32835833 NCBI chr11:33,909,417...33,917,674
Ensembl chr11:33,909,439...33,917,674
JBrowse link
G Ccdc120 coiled-coil domain containing 120 increases expression ISO triptolide results in increased expression of CCDC120 mRNA CTD PMID:32835833 NCBI chr  X:15,610,230...15,616,727
Ensembl chr  X:15,598,652...15,617,665
JBrowse link
G Ccdc15 coiled-coil domain containing 15 increases expression ISO triptolide results in increased expression of CCDC15 mRNA CTD PMID:32835833 NCBI chr 8:39,759,077...39,830,235
Ensembl chr 8:39,762,035...39,830,306
JBrowse link
G Ccdc180 coiled-coil domain containing 180 increases expression ISO triptolide results in increased expression of CCDC180 mRNA CTD PMID:32835833 NCBI chr 5:61,467,799...61,542,675
Ensembl chr 5:61,474,000...61,542,653
JBrowse link
G Ccdc196 coiled-coil domain containing 196 increases expression EXP triptolide results in increased expression of CCDC196 protein CTD PMID:32519852 NCBI chr 6:101,288,951...101,304,220
Ensembl chr 6:101,287,035...101,304,220
JBrowse link
G Ccdc62 coiled-coil domain containing 62 increases expression ISO triptolide results in increased expression of CCDC62 mRNA CTD PMID:32835833 NCBI chr12:38,057,532...38,093,916
Ensembl chr12:38,057,556...38,093,050
JBrowse link
G Ccdc86 coiled-coil domain containing 86 increases expression ISO triptolide results in increased expression of CCDC86 mRNA CTD PMID:32835833 NCBI chr 1:226,996,435...227,002,016
Ensembl chr 1:226,996,237...227,002,139
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression
multiple interactions
ISO triptolide results in increased expression of CCL11 mRNA
IL17A protein promotes the reaction [triptolide results in increased expression of CCL11 mRNA]
CTD PMID:24949944 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression
ISO triptolide promotes the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]
triptolide results in increased expression of CCL2 mRNA
CTD PMID:30633930 PMID:32835833 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccna1 cyclin A1 decreases expression ISO triptolide results in decreased expression of CCNA1 protein CTD PMID:12533674 NCBI chr 2:144,456,689...144,503,570
Ensembl chr 2:144,458,153...144,467,912
JBrowse link
G Ccna2 cyclin A2 increases expression EXP triptolide results in increased expression of CCNA2 mRNA CTD PMID:23639586 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb1 cyclin B1 increases expression
decreases expression
EXP
ISO
triptolide results in increased expression of CCNB1 mRNA
triptolide results in decreased expression of CCNB1 protein
CTD PMID:12533674 PMID:23639586 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnb2 cyclin B2 increases expression EXP triptolide results in increased expression of CCNB2 mRNA CTD PMID:23639586 NCBI chr 8:76,847,972...76,861,165 JBrowse link
G Ccnd1 cyclin D1 decreases expression EXP
ISO
triptolide results in decreased expression of CCND1 mRNA
triptolide results in decreased expression of CCND1 protein
CTD PMID:12533674 PMID:23639586 PMID:26990902 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd2 cyclin D2 increases expression EXP triptolide results in increased expression of CCND2 mRNA CTD PMID:23639586 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Ccne1 cyclin E1 increases expression ISO triptolide results in increased expression of CCNE1 protein CTD PMID:26990902 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Ccne2 cyclin E2 increases expression EXP triptolide results in increased expression of CCNE2 mRNA CTD PMID:23639586 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
JBrowse link
G Ccng1 cyclin G1 increases expression ISO triptolide results in increased expression of CCNG1 mRNA CTD PMID:32835833 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325
JBrowse link
G Cd24 CD24 molecule multiple interactions ISO triptolide inhibits the reaction [cobaltous chloride results in increased expression of CD24 protein] CTD PMID:24842335 NCBI chr20:48,335,540...48,340,847
Ensembl chr20:48,335,540...48,340,846
JBrowse link
G Cd36 CD36 molecule increases expression EXP triptolide results in increased expression of CD36 protein CTD PMID:32519852 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd44 CD44 molecule (Indian blood group) multiple interactions ISO triptolide inhibits the reaction [cobaltous chloride results in increased expression of CD44 protein] CTD PMID:24842335 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd47 Cd47 molecule increases expression EXP triptolide results in increased expression of CD47 protein CTD PMID:32519852 NCBI chr11:53,511,485...53,575,754
Ensembl chr11:53,514,595...53,575,175
JBrowse link
G Cd59 CD59 molecule increases expression EXP triptolide results in increased expression of CD59 protein CTD PMID:32519852 NCBI chr 3:94,010,481...94,028,660
Ensembl chr 3:94,010,475...94,028,621
JBrowse link
G Cd80 Cd80 molecule multiple interactions ISO triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CD80 protein] CTD PMID:15663903 NCBI chr11:64,815,201...64,855,293
Ensembl chr11:64,827,635...64,855,353
JBrowse link
G Cd86 CD86 molecule multiple interactions ISO triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CD86 protein] CTD PMID:15663903 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cdc16 cell division cycle 16 decreases expression EXP triptolide results in decreased expression of CDC16 mRNA CTD PMID:23639586 NCBI chr16:81,493,355...81,516,493
Ensembl chr16:81,493,355...81,516,493
JBrowse link
G Cdc25b cell division cycle 25B increases expression EXP triptolide results in increased expression of CDC25B mRNA CTD PMID:23639586 NCBI chr 3:123,731,539...123,741,696
Ensembl chr 3:123,731,539...123,741,339
JBrowse link
G Cdc42 cell division cycle 42 decreases expression EXP triptolide results in decreased expression of CDC42 mRNA; triptolide results in decreased expression of CDC42 protein CTD PMID:27554044 NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300
JBrowse link
G Cdc45 cell division cycle 45 increases expression EXP triptolide results in increased expression of CDC45 mRNA CTD PMID:23639586 NCBI chr11:86,328,785...86,354,099
Ensembl chr11:86,329,012...86,358,453
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression
decreases expression
EXP
ISO
triptolide results in increased expression of CDK1 mRNA
triptolide results in decreased expression of CDK1 protein
CTD PMID:12533674 PMID:23639586 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression
increases expression
EXP
ISO
triptolide results in decreased expression of CDK2 mRNA
triptolide results in decreased expression of CDK2 protein
triptolide results in increased expression of CDK2 protein
CTD PMID:12533674 PMID:23639586 PMID:26990902 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdk4 cyclin-dependent kinase 4 increases expression ISO triptolide results in increased expression of CDK4 protein CTD PMID:26990902 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdk6 cyclin-dependent kinase 6 increases expression ISO triptolide results in increased expression of CDK6 protein CTD PMID:26990902 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
G Cdk7 cyclin-dependent kinase 7 increases expression EXP triptolide results in increased expression of CDK7 mRNA CTD PMID:23639586 NCBI chr 2:30,710,642...30,735,522
Ensembl chr 2:30,710,643...30,735,514
JBrowse link
G Cdkl3 cyclin-dependent kinase-like 3 increases expression ISO triptolide results in increased expression of CDKL3 mRNA CTD PMID:32835833 NCBI chr10:37,458,397...37,510,345
Ensembl chr10:37,458,452...37,493,491
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP
ISO
triptolide results in increased expression of CDKN1A mRNA
triptolide results in increased expression of CDKN1A mRNA; triptolide results in increased expression of CDKN1A protein
CTD PMID:23639586 PMID:26990902 PMID:32835833 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression EXP triptolide results in increased expression of CDKN1B protein CTD PMID:32519852 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C increases expression EXP triptolide results in increased expression of CDKN2C mRNA CTD PMID:23639586 NCBI chr 5:129,347,731...129,352,886
Ensembl chr 5:129,347,732...129,352,886
JBrowse link
G Cdnf cerebral dopamine neurotrophic factor increases expression ISO triptolide results in increased expression of CDNF mRNA CTD PMID:32835833 NCBI chr17:78,721,230...78,735,324
Ensembl chr17:78,719,111...78,735,324
JBrowse link
G Cep170b centrosomal protein 170B increases expression ISO triptolide results in increased expression of CEP170B mRNA CTD PMID:32835833 NCBI chr 6:137,283,814...137,311,512
Ensembl chr 6:137,288,810...137,311,932
JBrowse link
G Cep63 centrosomal protein 63 increases expression ISO triptolide results in increased expression of CEP63 mRNA CTD PMID:32835833 NCBI chr 8:111,063,988...111,116,014
Ensembl chr 8:111,064,049...111,116,014
JBrowse link
G Ces1a carboxylesterase 1A increases expression ISO triptolide results in increased expression of CES1A mRNA CTD PMID:32835833 NCBI chr19:15,339,152...15,366,079
Ensembl chr19:15,339,152...15,366,079
JBrowse link
G Ces1d carboxylesterase 1D increases expression EXP triptolide results in increased expression of CES1D protein CTD PMID:32519852 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Ces4a carboxylesterase 4A decreases expression ISO triptolide results in decreased expression of CES4A mRNA CTD PMID:32835833 NCBI chr19:37,090,018...37,111,448
Ensembl chr19:37,090,056...37,107,872
JBrowse link
G Cfap20dc CFAP20 domain containing decreases expression ISO triptolide results in decreased expression of CFAP20DC mRNA CTD PMID:32835833 NCBI chr15:17,664,838...17,918,216
Ensembl chr15:17,775,692...17,924,302
JBrowse link
G Cfb complement factor B decreases expression ISO triptolide results in decreased expression of CFB mRNA CTD PMID:32835833 NCBI chr20:4,536,206...4,542,073
Ensembl chr20:4,536,203...4,561,066
Ensembl chr20:4,536,203...4,561,066
JBrowse link
G Cfh complement factor H increases expression
decreases expression
EXP
ISO
triptolide results in increased expression of CFH protein
triptolide results in decreased expression of CFH mRNA
CTD PMID:32519852 PMID:32835833 NCBI chr13:56,979,155...57,080,540
Ensembl chr13:56,978,607...57,080,622
JBrowse link
G Cfl2 cofilin 2 increases expression EXP triptolide results in increased expression of CFL2 protein CTD PMID:32519852 NCBI chr 6:75,759,140...75,763,185
Ensembl chr 6:75,759,140...75,763,185
JBrowse link
G Chchd3 coiled-coil-helix-coiled-coil-helix domain containing 3 increases expression EXP triptolide results in increased expression of CHCHD3 protein CTD PMID:32519852 NCBI chr 4:60,080,536...60,358,592
Ensembl chr 4:60,080,538...60,358,562
JBrowse link
G Chchd6 coiled-coil-helix-coiled-coil-helix domain containing 6 increases expression EXP triptolide results in increased expression of CHCHD6 protein CTD PMID:32519852 NCBI chr 4:121,340,952...121,565,222
Ensembl chr 4:121,340,952...121,565,212
JBrowse link
G Chka choline kinase alpha increases expression ISO triptolide results in increased expression of CHKA mRNA CTD PMID:32835833 NCBI chr 1:219,076,618...219,126,221
Ensembl chr 1:219,077,771...219,126,220
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit decreases expression ISO triptolide results in decreased expression of CHRNA4 mRNA CTD PMID:32835833 NCBI chr 3:176,533,182...176,547,965
Ensembl chr 3:176,527,516...176,548,208
JBrowse link
G Ciart circadian associated repressor of transcription decreases expression ISO triptolide results in decreased expression of CIART mRNA CTD PMID:32835833 NCBI chr 2:197,987,705...197,991,198
Ensembl chr 2:197,987,705...197,991,574
JBrowse link
G Cidec cell death-inducing DFFA-like effector c increases expression ISO triptolide results in increased expression of CIDEC mRNA CTD PMID:32835833 NCBI chr 4:145,377,482...145,390,497
Ensembl chr 4:145,377,431...145,390,497
JBrowse link
G Ckap2 cytoskeleton associated protein 2 increases expression ISO triptolide results in increased expression of CKAP2 mRNA CTD PMID:32835833 NCBI chr16:74,752,655...74,779,184
Ensembl chr16:74,752,655...74,779,184
JBrowse link
G Clcf1 cardiotrophin-like cytokine factor 1 increases expression ISO triptolide results in increased expression of CLCF1 mRNA CTD PMID:32835833 NCBI chr 1:219,468,866...219,472,445
Ensembl chr 1:219,468,675...219,472,654
JBrowse link
G Clcnkb chloride voltage-gated channel Kb increases expression EXP triptolide results in increased expression of CLCNKB protein CTD PMID:32519852 NCBI chr 5:159,950,384...159,973,576
Ensembl chr 5:159,950,392...159,962,676
JBrowse link
G Cldn11 claudin 11 decreases expression
multiple interactions
ISO triptolide results in decreased expression of CLDN11 mRNA; triptolide results in decreased expression of CLDN11 protein
10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [triptolide results in decreased expression of CLDN11 mRNA]; 10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [triptolide results in decreased expression of CLDN11 protein]
CTD PMID:30836114 NCBI chr 2:115,823,541...115,836,846
Ensembl chr 2:115,823,538...115,836,846
JBrowse link
G Clec11a C-type lectin domain containing 11A increases expression ISO triptolide results in increased expression of CLEC11A mRNA CTD PMID:32835833 NCBI chr 1:100,290,374...100,293,515
Ensembl chr 1:100,289,295...100,293,558
JBrowse link
G Clmn calmin decreases expression ISO triptolide results in decreased expression of CLMN mRNA CTD PMID:32835833 NCBI chr 6:128,473,592...128,567,267
Ensembl chr 6:128,473,570...128,567,198
JBrowse link
G Clpx caseinolytic mitochondrial matrix peptidase chaperone subunit X affects expression ISO triptolide affects the expression of CLPX mRNA CTD PMID:32835833 NCBI chr 8:70,789,137...70,843,133
Ensembl chr 8:70,789,256...70,843,123
JBrowse link
G Clu clusterin increases expression EXP triptolide results in increased expression of CLU protein CTD PMID:32519852 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Cluap1 clusterin associated protein 1 increases expression ISO triptolide results in increased expression of CLUAP1 mRNA CTD PMID:32835833 NCBI chr10:11,847,058...11,878,792
Ensembl chr10:11,847,102...11,878,792
JBrowse link
G Cmahp cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene decreases expression ISO triptolide results in decreased expression of CMAH mRNA CTD PMID:32835833 NCBI chr17:42,567,472...42,640,221
Ensembl chr17:42,583,945...42,640,221
JBrowse link
G Cmpk2 cytidine/uridine monophosphate kinase 2 increases expression EXP triptolide results in increased expression of CMPK2 protein CTD PMID:32519852 NCBI chr 6:45,683,242...45,694,824
Ensembl chr 6:45,683,234...45,694,822
JBrowse link
G Cnbp CCHC-type zinc finger, nucleic acid binding protein decreases expression EXP triptolide results in decreased expression of CNBP protein CTD PMID:32519852 NCBI chr 4:119,747,890...119,756,787
Ensembl chr 4:119,747,911...119,756,765
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase increases expression
decreases expression
EXP
ISO
triptolide results in increased expression of CNP protein
triptolide results in decreased expression of CNP mRNA
CTD PMID:32519852 PMID:32835833 NCBI chr10:88,490,798...88,497,357
Ensembl chr10:88,490,798...88,497,356
JBrowse link
G Cog5 component of oligomeric golgi complex 5 decreases expression EXP triptolide results in decreased expression of COG5 protein CTD PMID:32519852 NCBI chr 6:50,953,868...51,230,860
Ensembl chr 6:50,954,631...51,230,701
JBrowse link
G Col11a2 collagen type XI alpha 2 chain increases expression ISO triptolide results in increased expression of COL11A2 mRNA CTD PMID:32835833 NCBI chr20:3,829,324...3,859,022
Ensembl chr20:3,830,164...3,859,018
JBrowse link
G Col12a1 collagen type XII alpha 1 chain increases expression ISO triptolide results in increased expression of COL12A1 mRNA CTD PMID:32835833 NCBI chr 8:87,042,820...87,150,701
Ensembl chr 8:87,040,799...87,158,368
JBrowse link
G Col20a1 collagen type XX alpha 1 chain increases expression ISO triptolide results in increased expression of COL20A1 mRNA CTD PMID:32835833 NCBI chr 3:176,491,292...176,526,009
Ensembl chr 3:176,494,768...176,526,018
JBrowse link
G Col7a1 collagen type VII alpha 1 chain increases expression ISO triptolide results in increased expression of COL7A1 mRNA CTD PMID:32835833 NCBI chr 8:117,694,441...117,726,844
Ensembl chr 8:117,694,605...117,726,844
JBrowse link
G Comt catechol-O-methyltransferase decreases expression EXP triptolide results in decreased expression of COMT protein CTD PMID:32519852 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Cp ceruloplasmin increases expression EXP triptolide results in increased expression of CP protein CTD PMID:32519852 NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853
JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 decreases expression ISO triptolide results in decreased expression of CPS1 mRNA CTD PMID:32835833 NCBI chr 9:74,113,437...74,236,274
Ensembl chr 9:74,124,016...74,236,274
JBrowse link
G Cpsf2 cleavage and polyadenylation specific factor 2 decreases expression EXP triptolide results in decreased expression of CPSF2 protein CTD PMID:32519852 NCBI chr 6:125,870,372...125,898,039
Ensembl chr 6:125,870,372...125,898,874
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression ISO triptolide results in increased expression of CPT1A mRNA CTD PMID:29723566 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B decreases expression ISO triptolide results in decreased expression of CPT1B mRNA CTD PMID:31241159 NCBI chr 7:130,395,211...130,404,731
Ensembl chr 7:130,395,194...130,405,347
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 decreases expression ISO triptolide results in decreased expression of CPT2 mRNA CTD PMID:31241159 NCBI chr 5:127,505,646...127,523,016
Ensembl chr 5:127,505,614...127,523,089
JBrowse link
G Crbn cereblon increases expression EXP triptolide results in increased expression of CRBN protein CTD PMID:32519852 NCBI chr 4:138,864,910...138,885,786
Ensembl chr 4:138,866,761...138,885,556
JBrowse link
G Creb3l4 cAMP responsive element binding protein 3-like 4 increases expression ISO triptolide results in increased expression of CREB3L4 mRNA CTD PMID:32835833 NCBI chr 2:189,596,657...189,602,243
Ensembl chr 2:189,595,415...189,602,143
JBrowse link
G Crem cAMP responsive element modulator decreases expression EXP triptolide results in decreased expression of CREM mRNA CTD PMID:23639586 NCBI chr17:57,021,704...57,090,888
Ensembl chr17:57,031,766...57,090,888
JBrowse link
G Crip2 cysteine-rich protein 2 increases expression ISO triptolide results in increased expression of CRIP2 mRNA CTD PMID:32835833 NCBI chr 6:137,953,545...137,958,491
Ensembl chr 6:137,953,545...137,958,490
JBrowse link
G Crk CRK proto-oncogene, adaptor protein decreases expression
increases expression
EXP triptolide results in decreased expression of CRK mRNA
triptolide results in increased expression of CRK mRNA
CTD PMID:23639586 NCBI chr10:63,829,731...63,855,999
Ensembl chr10:63,829,807...63,852,780
JBrowse link
G Crp C-reactive protein increases expression
decreases expression
EXP
ISO
triptolide results in increased expression of CRP protein
triptolide results in decreased expression of CRP mRNA
CTD PMID:32519852 PMID:32835833 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Cry1 cryptochrome circadian regulator 1 increases expression ISO triptolide results in increased expression of CRY1 mRNA CTD PMID:32835833 NCBI chr 7:24,534,593...24,634,098
Ensembl chr 7:24,534,615...24,634,097
JBrowse link
G Cryab crystallin, alpha B increases expression ISO triptolide results in increased expression of CRYAB mRNA CTD PMID:32835833 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
JBrowse link
G Cspg5 chondroitin sulfate proteoglycan 5 decreases expression ISO triptolide results in decreased expression of CSPG5 mRNA CTD PMID:32835833 NCBI chr 8:118,333,695...118,348,040
Ensembl chr 8:118,333,706...118,347,582
JBrowse link
G Ctf1 cardiotrophin 1 decreases expression ISO triptolide results in decreased expression of CTF1 mRNA CTD PMID:32835833 NCBI chr 1:199,162,319...199,168,296
Ensembl chr 1:199,163,086...199,168,296
JBrowse link
G Ctps1 CTP synthase 1 increases expression ISO triptolide results in increased expression of CTPS mRNA CTD PMID:32835833 NCBI chr 5:139,475,934...139,505,065
Ensembl chr 5:139,475,934...139,505,065
JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 affects expression ISO triptolide affects the expression of CXCL11 mRNA CTD PMID:32835833 NCBI chr14:17,195,395...17,198,170
Ensembl chr14:17,195,014...17,198,291
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression
multiple interactions
ISO triptolide results in increased expression of CXCL2 mRNA
IL17A protein promotes the reaction [triptolide results in increased expression of CXCL2 mRNA]
CTD PMID:24949944 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions
increases expression
ISO IL17A protein promotes the reaction [triptolide results in increased expression of CXCL1 mRNA]; triptolide inhibits the reaction [Chlorine results in increased expression of CXCL1 protein] CTD PMID:20348278 PMID:24949944 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 decreases expression ISO triptolide results in decreased expression of CXCR4 protein CTD PMID:26420756 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 decreases expression ISO triptolide results in decreased expression of CYB5R3 mRNA CTD PMID:32835833 NCBI chr 7:124,024,003...124,041,564
Ensembl chr 7:124,023,995...124,041,594
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions
decreases expression
EXP
ISO
triptolide results in decreased expression of and results in decreased activity of CYP11A1 protein
[Colforsin co-treated with triptolide] results in decreased expression of CYP11A1 mRNA
triptolide results in decreased expression of CYP11A1 mRNA
CTD PMID:22592319 PMID:31557376 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 multiple interactions ISO [Colforsin co-treated with triptolide] results in decreased expression of CYP11B1 mRNA CTD PMID:31557376 NCBI chr 7:116,248,759...116,255,205
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 multiple interactions ISO [Colforsin co-treated with triptolide] results in decreased expression of CYP11B2 mRNA CTD PMID:31557376 NCBI chr 7:116,155,928...116,161,781
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions
decreases expression
ISO [Colforsin co-treated with triptolide] results in decreased expression of CYP17A1 mRNA
triptolide results in decreased expression of CYP17A1 mRNA
CTD PMID:31557376 PMID:32835833 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 affects expression ISO triptolide affects the expression of CYP26A1 mRNA CTD PMID:32835833 NCBI chr 1:256,382,861...256,386,729
Ensembl chr 1:256,382,791...256,386,729
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 decreases expression ISO triptolide results in decreased expression of CYP27A1 mRNA CTD PMID:32987112 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 increases expression ISO triptolide results in increased expression of CYP27B1 mRNA CTD PMID:32835833 NCBI chr 7:70,333,150...70,340,006
Ensembl chr 7:70,335,061...70,340,005
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 multiple interactions ISO TRAJ18 protein affects the reaction [triptolide results in decreased expression of CYP2A1 mRNA] CTD PMID:32987112 NCBI chr 1:83,711,223...83,725,222
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions
decreases expression
ISO
EXP
TRAJ18 protein affects the reaction [triptolide results in decreased expression of CYP2B10 mRNA]
triptolide results in decreased expression of CYP2B1 mRNA
CTD PMID:32835833 PMID:32987112 PMID:33600922 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases expression EXP triptolide results in decreased expression of CYP2C11 protein CTD PMID:32519852 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases expression EXP
ISO
triptolide results in decreased expression of CYP2C8 protein
triptolide results in decreased expression of CYP2C29 mRNA
CTD PMID:32835833 PMID:33600922 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 decreases expression ISO triptolide results in decreased expression of CYP39A1 mRNA CTD PMID:32835833 NCBI chr 9:19,804,079...19,880,346
Ensembl chr 9:19,804,079...19,880,346
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects metabolic processing
decreases expression
EXP CYP3A2 affects the metabolism of triptolide
triptolide results in decreased expression of CYP3A4 protein
CTD PMID:20223271 PMID:33600922 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 decreases expression
decreases activity
EXP triptolide results in decreased expression of CYP3A23-3A1 mRNA
triptolide results in decreased activity of CYP3A23-3A1 protein
CTD PMID:33600922 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 decreases expression ISO triptolide results in decreased expression of CYP4F14 mRNA CTD PMID:32835833 NCBI chr 7:15,179,472...15,191,113
Ensembl chr 7:15,179,467...15,190,796
JBrowse link
G Cyp51 cytochrome P450, family 51 decreases expression ISO triptolide results in decreased expression of CYP51 mRNA CTD PMID:32835833 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions
decreases expression
ISO TRAJ18 protein affects the reaction [triptolide results in decreased expression of CYP7A1 mRNA] CTD PMID:32987112 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 multiple interactions
decreases expression
ISO TRAJ18 protein affects the reaction [triptolide results in decreased expression of CYP8B1 mRNA] CTD PMID:32835833 PMID:32987112 NCBI chr 8:130,548,418...130,550,388
Ensembl chr 8:130,548,418...130,550,388
JBrowse link
G Dbp D-box binding PAR bZIP transcription factor decreases expression ISO triptolide results in decreased expression of DBP mRNA CTD PMID:32835833 NCBI chr 1:101,687,896...101,692,845
Ensembl chr 1:101,687,855...101,692,846
JBrowse link
G Dclk3 doublecortin-like kinase 3 decreases expression ISO triptolide results in decreased expression of DCLK3 mRNA CTD PMID:32835833 NCBI chr 8:119,691,567...119,744,484
Ensembl chr 8:119,691,388...119,744,506
JBrowse link
G Ddias DNA damage-induced apoptosis suppressor increases expression ISO triptolide results in increased expression of DDIAS mRNA CTD PMID:32835833 NCBI chr 1:157,675,754...157,700,064
Ensembl chr 1:157,675,765...157,700,064
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO triptolide results in increased expression of DDIT3 protein CTD PMID:26990902 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddit4l DNA-damage-inducible transcript 4-like increases expression ISO triptolide results in increased expression of DDIT4L mRNA CTD PMID:32835833 NCBI chr 2:242,882,219...242,885,088
Ensembl chr 2:242,882,306...242,885,131
JBrowse link
G Ddrgk1 DDRGK domain containing 1 decreases expression EXP triptolide results in decreased expression of DDRGK1 protein CTD PMID:32519852 NCBI chr 3:123,195,580...123,206,828
Ensembl chr 3:123,195,580...123,206,828
JBrowse link
G Ddx17 DEAD-box helicase 17 increases expression ISO triptolide results in increased expression of DDX17 mRNA CTD PMID:32835833 NCBI chr 7:120,761,843...120,765,012
Ensembl chr 7:120,761,826...120,780,641
JBrowse link
G Defb1 defensin beta 1 decreases expression ISO triptolide results in decreased expression of DEFB1 mRNA CTD PMID:32835833 NCBI chr16:75,294,385...75,309,127
Ensembl chr16:75,294,376...75,309,176
JBrowse link
G Dennd1a DENN domain containing 1A increases expression EXP triptolide results in increased expression of DENND1A protein CTD PMID:32519852 NCBI chr 3:22,061,120...22,501,502
Ensembl chr 3:22,058,400...22,500,765
JBrowse link
G Depp1 DEPP1, autophagy regulator decreases expression ISO triptolide results in decreased expression of DEPP1 mRNA CTD PMID:32835833 NCBI chr 4:148,780,330...148,784,566
Ensembl chr 4:148,782,479...148,784,562
JBrowse link
G Des desmin multiple interactions EXP triptolide inhibits the reaction [Puromycin Aminonucleoside results in increased expression of DES protein] CTD PMID:18509322 NCBI chr 9:82,556,574...82,564,288
Ensembl chr 9:82,556,573...82,564,294
JBrowse link
G Dglucy D-glutamate cyclase decreases expression EXP triptolide results in decreased expression of DGLUCY protein CTD PMID:32519852 NCBI chr 6:124,786,164...124,870,244
Ensembl chr 6:124,786,097...124,872,277
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase decreases expression ISO triptolide results in decreased expression of DHCR7 mRNA CTD PMID:32835833 NCBI chr 1:217,018,916...217,034,890
Ensembl chr 1:217,018,916...217,034,904
JBrowse link
G Dhrs7 dehydrogenase/reductase 7 decreases expression ISO triptolide results in decreased expression of DHRS7 mRNA CTD PMID:32835833 NCBI chr 6:95,522,577...95,541,393
Ensembl chr 6:95,522,577...95,541,393
JBrowse link
G Dhrs7b dehydrogenase/reductase 7B increases expression EXP triptolide results in increased expression of DHRS7B protein CTD PMID:32519852 NCBI chr10:47,065,755...47,111,089
Ensembl chr10:47,065,850...47,111,101
JBrowse link
G Dhrs7l1 dehydrogenase/reductase (SDR family) member 7-like 1 decreases expression EXP triptolide results in decreased expression of DHRS7L1 protein CTD PMID:32519852 NCBI chr 6:95,387,709...95,502,845
Ensembl chr 6:95,387,718...95,502,845
JBrowse link
G Dhx29 DExH-box helicase 29 increases expression ISO triptolide results in increased expression of DHX29 mRNA CTD PMID:32835833 NCBI chr 2:44,787,066...44,837,834
Ensembl chr 2:44,787,002...44,837,831
JBrowse link
G Dhx37 DEAH-box helicase 37 increases expression ISO triptolide results in increased expression of DHX37 mRNA CTD PMID:32835833 NCBI chr12:36,594,058...36,614,165
Ensembl chr12:36,594,047...36,614,210
JBrowse link
G Dhx38 DEAH-box helicase 38 increases expression ISO triptolide results in increased expression of DHX38 mRNA CTD PMID:32835833 NCBI chr19:42,110,291...42,127,540
Ensembl chr19:42,110,327...42,127,542
JBrowse link
G Dhx58 DEXH-box helicase 58 increases expression EXP triptolide results in increased expression of DHX58 protein CTD PMID:32519852 NCBI chr10:88,599,722...88,611,562
Ensembl chr10:88,599,680...88,611,105
JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases expression ISO triptolide results in decreased expression of DIO1 mRNA CTD PMID:32835833 NCBI chr 5:126,894,837...126,911,532
Ensembl chr 5:126,895,286...126,911,520
JBrowse link
G Dixdc1 DIX domain containing 1 decreases expression ISO triptolide results in decreased expression of DIXDC1 mRNA CTD PMID:32835833 NCBI chr 8:55,091,232...55,164,636
Ensembl chr 8:55,091,235...55,162,421
JBrowse link
G Dnah10 dynein, axonemal, heavy chain 10 increases expression ISO triptolide results in increased expression of DNAH10 mRNA CTD PMID:32835833 NCBI chr12:37,237,482...37,365,258 JBrowse link
G Dnah5 dynein, axonemal, heavy chain 5 increases expression ISO triptolide results in increased expression of DNAH5 mRNA CTD PMID:32835833 NCBI chr 2:80,947,730...81,143,997
NCBI chr 2:81,159,060...81,337,560
Ensembl chr 2:80,948,658...81,143,447
JBrowse link
G Dnai7 dynein axonemal intermediate chain 7 increases expression ISO triptolide results in increased expression of CASC1 mRNA CTD PMID:32835833 NCBI chr 4:179,440,984...179,476,965
Ensembl chr 4:179,440,953...179,477,070
JBrowse link
G Dnajb12 DnaJ heat shock protein family (Hsp40) member B12 increases expression EXP triptolide results in increased expression of DNAJB12 protein CTD PMID:32519852 NCBI chr20:29,445,510...29,463,739
Ensembl chr20:29,445,510...29,463,738
JBrowse link
G Dnajc6 DnaJ heat shock protein family (Hsp40) member C6 decreases expression EXP triptolide results in decreased expression of DNAJC6 protein CTD PMID:32519852 NCBI chr 5:120,330,372...120,492,515
Ensembl chr 5:120,340,646...120,492,487
JBrowse link
G Dnhd1 dynein heavy chain domain 1 increases expression ISO triptolide results in increased expression of DNHD1 mRNA CTD PMID:32835833 NCBI chr 1:170,473,792...170,570,220
Ensembl chr 1:170,471,272...170,565,063
JBrowse link
G Dnm1l dynamin 1-like multiple interactions
decreases expression
ISO 10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [triptolide results in decreased expression of DNM1L protein] CTD PMID:30836114 NCBI chr11:88,830,968...88,882,271
Ensembl chr11:88,830,957...88,880,198
JBrowse link
G Dpep1 dipeptidase 1 increases expression EXP triptolide results in increased expression of DPEP1 protein CTD PMID:32519852 NCBI chr19:55,973,447...55,998,830
Ensembl chr19:55,982,740...55,998,208
JBrowse link
G Dpp4 dipeptidylpeptidase 4 affects expression EXP triptolide affects the expression of DPP4 protein CTD PMID:32519852 NCBI chr 3:48,291,055...48,372,672
Ensembl chr 3:48,291,055...48,372,672
JBrowse link
G Dtnbp1 dystrobrevin binding protein 1 decreases expression EXP triptolide results in decreased expression of DTNBP1 protein CTD PMID:32519852 NCBI chr17:20,090,136...20,182,332
Ensembl chr17:20,090,246...20,182,206
JBrowse link
G Dtx4 deltex E3 ubiquitin ligase 4 increases expression ISO triptolide results in increased expression of DTX4 mRNA CTD PMID:32835833 NCBI chr 1:228,729,842...228,759,783
Ensembl chr 1:228,732,985...228,755,866
JBrowse link
G Dusp1 dual specificity phosphatase 1 decreases expression ISO triptolide results in decreased expression of DUSP1 protein CTD PMID:17507666 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Dync2h1 dynein cytoplasmic 2 heavy chain 1 increases expression EXP triptolide results in increased expression of DYNC2H1 protein CTD PMID:32519852 NCBI chr 8:5,217,054...5,436,969
Ensembl chr 8:5,217,217...5,429,581
JBrowse link
G Dynll1 dynein light chain LC8-type 1 increases expression ISO triptolide results in increased expression of DYNLL1 mRNA CTD PMID:32835833 NCBI chr12:47,074,200...47,076,573
Ensembl chr12:47,074,200...47,076,572
JBrowse link
G E2f1 E2F transcription factor 1 increases expression EXP triptolide results in increased expression of E2F1 mRNA CTD PMID:23639586 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G E2f3 E2F transcription factor 3 increases expression EXP triptolide results in increased expression of E2F3 mRNA CTD PMID:23639586 NCBI chr17:36,334,136...36,408,831
Ensembl chr17:36,334,147...36,408,831
JBrowse link
G Ears2 glutamyl-tRNA synthetase 2, mitochondrial increases expression ISO triptolide results in increased expression of EARS2 mRNA CTD PMID:32835833 NCBI chr 1:191,997,512...192,025,350
Ensembl chr 1:191,997,512...192,025,350
JBrowse link
G Echdc1 ethylmalonyl-CoA decarboxylase 1 decreases expression ISO triptolide results in decreased expression of ECHDC1 mRNA CTD PMID:32835833 NCBI chr 1:30,874,410...30,921,117
Ensembl chr 1:30,874,418...30,917,882
JBrowse link
G Echdc2 enoyl CoA hydratase domain containing 2 decreases expression EXP triptolide results in decreased expression of ECHDC2 protein CTD PMID:32519852 NCBI chr 5:127,770,570...127,789,568
Ensembl chr 5:127,770,570...127,789,567
JBrowse link
G Eda2r ectodysplasin A2 receptor increases expression ISO triptolide results in increased expression of EDA2R mRNA CTD PMID:32835833 NCBI chr  X:66,560,200...66,602,509
Ensembl chr  X:66,561,286...66,602,506
JBrowse link
G Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 increases expression ISO triptolide results in increased expression of EEF1E1 mRNA CTD PMID:32835833 NCBI chr17:26,785,017...26,795,723
Ensembl chr17:26,785,029...26,797,161
JBrowse link
G Efnb3 ephrin B3 increases expression ISO triptolide results in increased expression of EFNB3 mRNA CTD PMID:32835833 NCBI chr10:56,161,431...56,168,819
Ensembl chr10:56,161,432...56,167,426
JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO triptolide results in decreased expression of EGFR mRNA CTD PMID:32835833 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Ehd2 EH-domain containing 2 increases expression EXP triptolide results in increased expression of EHD2 protein CTD PMID:32519852 NCBI chr 1:77,847,599...77,865,870
Ensembl chr 1:77,847,600...77,865,870
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase increases expression ISO triptolide results in increased expression of EHHADH mRNA CTD PMID:29723566 NCBI chr11:82,945,104...82,978,364
Ensembl chr11:82,945,104...82,978,364
JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 increases expression EXP triptolide results in increased expression of EIF2AK2 protein CTD PMID:32519852 NCBI chr 6:1,428,845...1,466,193
Ensembl chr 6:1,428,834...1,466,201
JBrowse link
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta increases expression EXP triptolide results in increased expression of EIF2B4 protein CTD PMID:32519852 NCBI chr 6:26,546,917...26,552,474
Ensembl chr 6:26,546,924...26,552,430
JBrowse link
G Eif4e eukaryotic translation initiation factor 4E increases expression ISO triptolide results in increased expression of EIF4E mRNA CTD PMID:32835833 NCBI chr 2:243,819,616...243,853,987
Ensembl chr 2:243,820,661...243,852,631
JBrowse link
G Eif4ebp3 eukaryotic translation initiation factor 4E binding protein 3 decreases expression ISO triptolide results in decreased expression of EIF4EBP3 mRNA CTD PMID:32835833 NCBI chr18:29,490,981...29,492,727
Ensembl chr18:29,386,809...29,492,718
JBrowse link
G Eipr1 EARP complex and GARP complex interacting protein 1 increases expression EXP triptolide results in increased expression of EIPR1 protein CTD PMID:32519852 NCBI chr 6:48,021,771...48,135,241
Ensembl chr 6:48,021,771...48,135,241
JBrowse link
G Elf3 E74 like ETS transcription factor 3 increases expression ISO triptolide results in increased expression of ELF3 mRNA CTD PMID:32835833 NCBI chr13:52,083,873...52,088,798
Ensembl chr13:52,083,859...52,088,780
JBrowse link
G Elovl2 ELOVL fatty acid elongase 2 decreases expression ISO triptolide results in decreased expression of ELOVL2 mRNA CTD PMID:32835833 NCBI chr17:21,382,461...21,422,413
Ensembl chr17:21,382,455...21,422,407
JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 decreases expression ISO triptolide results in decreased expression of ELOVL5 mRNA CTD PMID:32835833 NCBI chr 8:85,220,941...85,287,449
Ensembl chr 8:85,259,982...85,285,983
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 decreases expression ISO triptolide results in decreased expression of ELOVL6 mRNA CTD PMID:32835833 NCBI chr 2:234,187,490...234,296,124
Ensembl chr 2:234,189,105...234,296,145
Ensembl chr 2:234,189,105...234,296,145
JBrowse link
G Emc3 ER membrane protein complex subunit 3 increases expression EXP triptolide results in increased expression of EMC3 protein CTD PMID:32519852 NCBI chr 4:145,471,466...145,487,375
Ensembl chr 4:145,471,454...145,487,426
JBrowse link
G Emc8 ER membrane protein complex subunit 8 increases expression EXP triptolide results in increased expression of EMC8 protein CTD PMID:32519852 NCBI chr19:54,235,949...54,245,810
Ensembl chr19:54,235,936...54,245,855
JBrowse link
G Eme2 essential meiotic structure-specific endonuclease subunit 2 increases expression ISO triptolide results in increased expression of EME2 mRNA CTD PMID:32835833 NCBI chr10:14,253,552...14,257,017
Ensembl chr10:14,254,252...14,256,930
JBrowse link
G Enc1 ectodermal-neural cortex 1 increases expression ISO triptolide results in increased expression of ENC1 mRNA CTD PMID:32835833 NCBI chr 2:28,049,217...28,061,023
Ensembl chr 2:28,049,217...28,061,029
JBrowse link
G Endod1 endonuclease domain containing 1 increases expression ISO triptolide results in increased expression of ENDOD1 mRNA CTD PMID:32835833 NCBI chr 8:12,898,430...12,928,156 JBrowse link
G Endog endonuclease G increases expression ISO triptolide results in increased expression of ENDOG protein CTD PMID:26990902 NCBI chr 3:8,741,833...8,744,414
Ensembl chr 3:8,741,766...8,744,592
JBrowse link
G Eno3 enolase 3 increases expression ISO triptolide results in increased expression of ENO3 mRNA CTD PMID:32835833 NCBI chr10:57,278,271...57,283,661
Ensembl chr10:57,278,307...57,283,653
JBrowse link
G Enpep glutamyl aminopeptidase affects expression EXP triptolide affects the expression of ENPEP protein CTD PMID:32519852 NCBI chr 2:233,667,253...233,743,866
Ensembl chr 2:233,667,254...233,743,866
JBrowse link
G Erlin1 ER lipid raft associated 1 increases expression EXP triptolide results in increased expression of ERLIN1 protein CTD PMID:32519852 NCBI chr 1:263,810,439...263,845,762
Ensembl chr 1:263,810,439...263,845,762
JBrowse link
G Ermp1 endoplasmic reticulum metallopeptidase 1 increases expression EXP triptolide results in increased expression of ERMP1 protein CTD PMID:32519852 NCBI chr 1:247,784,830...247,821,771
Ensembl chr 1:247,787,582...247,821,728
JBrowse link
G Espl1 extra spindle pole bodies like 1, separase increases expression EXP triptolide results in increased expression of ESPL1 mRNA CTD PMID:23639586 NCBI chr 7:143,896,890...143,923,868
Ensembl chr 7:143,897,014...143,923,868
JBrowse link
G Esrrb estrogen-related receptor beta increases expression EXP triptolide results in increased expression of ESRRB protein CTD PMID:32519852 NCBI chr 6:110,360,940...110,458,406
Ensembl chr 6:110,410,141...110,455,906
JBrowse link
G Exoc4 exocyst complex component 4 increases expression ISO triptolide results in increased expression of EXOC4 mRNA CTD PMID:32835833 NCBI chr 4:60,549,128...61,358,305
Ensembl chr 4:60,549,197...61,355,994
JBrowse link
G Exosc9 exosome component 9 increases expression ISO triptolide results in increased expression of EXOSC9 mRNA CTD PMID:32835833 NCBI chr 2:123,264,679...123,275,623
Ensembl chr 2:123,264,694...123,294,880
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit decreases expression ISO triptolide results in decreased expression of EZH2 protein CTD PMID:19879315 NCBI chr 4:77,284,404...77,347,011
Ensembl chr 4:77,284,404...77,347,011
JBrowse link
G F11 coagulation factor XI decreases expression ISO triptolide results in decreased expression of F11 mRNA CTD PMID:32835833 NCBI chr16:50,179,458...50,201,644
Ensembl chr16:50,179,458...50,201,698
JBrowse link
G F2rl3 F2R like thrombin or trypsin receptor 3 increases expression ISO triptolide results in increased expression of F2RL3 mRNA CTD PMID:32835833 NCBI chr16:18,817,797...18,819,790
Ensembl chr16:18,814,622...18,819,833
JBrowse link
G F5 coagulation factor V increases expression EXP triptolide results in increased expression of F5 protein CTD PMID:32519852 NCBI chr13:82,479,997...82,535,540
Ensembl chr13:82,479,998...82,535,534
JBrowse link
G F9 coagulation factor IX increases expression EXP triptolide results in increased expression of F9 protein CTD PMID:32519852 NCBI chr  X:143,097,507...143,141,791
Ensembl chr  X:143,097,525...143,141,794
JBrowse link
G Fabp1 fatty acid binding protein 1 decreases expression ISO triptolide results in decreased expression of FABP1 mRNA CTD PMID:32835833 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954
JBrowse link
G Fabp4 fatty acid binding protein 4 increases expression EXP triptolide results in increased expression of FABP4 protein CTD PMID:32519852 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fabp5 fatty acid binding protein 5 decreases expression ISO triptolide results in decreased expression of FABP5 mRNA CTD PMID:32835833 NCBI chr 2:93,981,662...93,985,322
Ensembl chr 2:93,981,656...93,985,378
JBrowse link
G Fads1 fatty acid desaturase 1 decreases expression ISO triptolide results in decreased expression of FADS1 mRNA CTD PMID:32835833 NCBI chr 1:226,234,034...226,249,118
Ensembl chr 1:226,234,074...226,249,138
JBrowse link
G Fads2 fatty acid desaturase 2 decreases expression ISO triptolide results in decreased expression of FADS2 mRNA CTD PMID:32835833 NCBI chr 1:225,906,582...226,152,568
Ensembl chr 1:226,114,413...226,152,524
JBrowse link
G Fam107a family with sequence similarity 107, member A decreases expression ISO triptolide results in decreased expression of FAM107A mRNA CTD PMID:32835833 NCBI chr15:18,399,145...18,415,959
Ensembl chr15:18,399,515...18,415,965
JBrowse link
G Fam161b FAM161 centrosomal protein B increases expression ISO triptolide results in increased expression of FAM161B mRNA CTD PMID:32835833 NCBI chr 6:108,060,019...108,076,303
Ensembl chr 6:108,061,063...108,076,186
JBrowse link
G Fam210b family with sequence similarity 210, member B increases expression EXP triptolide results in increased expression of FAM210B protein CTD PMID:32519852 NCBI chr 3:170,354,109...170,364,265
Ensembl chr 3:170,354,141...170,362,513
JBrowse link
G Fam47e family with sequence similarity 47, member E decreases expression ISO triptolide results in decreased expression of FAM47E mRNA CTD PMID:32835833 NCBI chr14:16,991,496...17,027,563 JBrowse link
G Fam71e1 family with sequence similarity 71, member E1 increases expression ISO triptolide results in increased expression of FAM71E1 mRNA CTD PMID:32835833 NCBI chr 1:100,501,556...100,507,334
Ensembl chr 1:100,501,676...100,506,022
JBrowse link
G Fam83h family with sequence similarity 83, member H increases expression ISO triptolide results in increased expression of FAM83H mRNA CTD PMID:32835833 NCBI chr 7:117,062,748...117,070,936
Ensembl chr 7:117,062,692...117,070,936
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO triptolide results in increased expression of FAS protein CTD PMID:26990902 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand multiple interactions
increases expression
ISO IL17A protein promotes the reaction [triptolide results in increased expression of FASL mRNA]
triptolide results in increased expression of FASL mRNA; triptolide results in increased expression of FASL protein
CTD PMID:24949944 PMID:26990902 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fasn fatty acid synthase decreases expression ISO triptolide results in decreased expression of FASN mRNA CTD PMID:32835833 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fbn2 fibrillin 2 decreases expression EXP triptolide results in decreased expression of FBN2 protein CTD PMID:32519852 NCBI chr18:53,068,495...53,272,254
Ensembl chr18:53,068,495...53,181,503
JBrowse link
G Fbp2 fructose-bisphosphatase 2 decreases expression EXP triptolide results in decreased expression of FBP2 mRNA CTD PMID:23639586 NCBI chr17:372,554...389,918
Ensembl chr17:372,551...389,967
JBrowse link
G Fbxl4 F-box and leucine-rich repeat protein 4 increases expression EXP triptolide results in increased expression of FBXL4 protein CTD PMID:32519852 NCBI chr 5:36,555,061...36,628,920
Ensembl chr 5:36,555,109...36,629,689
JBrowse link
G Fbxo7 F-box protein 7 increases expression EXP triptolide results in increased expression of FBXO7 protein CTD PMID:32519852 NCBI chr 7:23,815,246...23,843,505
Ensembl chr 7:23,815,245...23,843,634
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression EXP triptolide results in increased expression of FDFT1 protein CTD PMID:32519852 NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302
JBrowse link
G Fdps farnesyl diphosphate synthase decreases expression ISO triptolide results in decreased expression of FDPS mRNA CTD PMID:32835833 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
JBrowse link
G Fetub fetuin B increases expression EXP triptolide results in increased expression of FETUB protein CTD PMID:32519852 NCBI chr11:81,648,890...81,660,472
Ensembl chr11:81,648,885...81,660,395
JBrowse link
G Ffar4 free fatty acid receptor 4 increases expression ISO triptolide results in increased expression of FFAR4 mRNA CTD PMID:32835833 NCBI chr 1:256,786,124...256,804,156
Ensembl chr 1:256,786,124...256,804,156
JBrowse link
G Fga fibrinogen alpha chain increases expression EXP triptolide results in increased expression of FGA protein CTD PMID:32519852 NCBI chr 2:181,997,562...182,013,726
Ensembl chr 2:182,006,242...182,013,763
JBrowse link
G Fgb fibrinogen beta chain increases expression EXP triptolide results in increased expression of FGB protein CTD PMID:32519852 NCBI chr 2:182,028,044...182,035,026
Ensembl chr 2:182,027,115...182,038,178
JBrowse link
G Fgf1 fibroblast growth factor 1 decreases expression EXP triptolide results in decreased expression of FGF1 protein CTD PMID:32519852 NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824
JBrowse link
G Fgfrl1 fibroblast growth factor receptor-like 1 decreases expression ISO triptolide results in decreased expression of FGFRL1 mRNA CTD PMID:32835833 NCBI chr14:2,020,110...2,032,169
Ensembl chr14:2,018,500...2,032,593
JBrowse link
G Fgg fibrinogen gamma chain increases expression EXP triptolide results in increased expression of FGG protein CTD PMID:32519852 NCBI chr 2:181,987,080...181,994,523
Ensembl chr 2:181,987,217...181,994,514
JBrowse link
G Fjx1 four-jointed box kinase 1 increases expression EXP triptolide results in increased expression of FJX1 protein CTD PMID:32519852 NCBI chr 3:92,288,818...92,290,919
Ensembl chr 3:92,288,818...92,290,919
JBrowse link
G Fkbp11 FKBP prolyl isomerase 11 decreases expression ISO triptolide results in decreased expression of FKBP11 mRNA CTD PMID:32835833 NCBI chr 7:140,398,253...140,402,664
Ensembl chr 7:140,398,199...140,437,467
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 decreases expression ISO triptolide results in decreased expression of FKBP5 mRNA CTD PMID:32835833 NCBI chr20:7,976,704...8,097,290
Ensembl chr20:7,976,713...8,019,020
JBrowse link
G Fmn1 formin 1 decreases expression ISO triptolide results in decreased expression of FMN1 mRNA CTD PMID:32835833 NCBI chr 3:104,783,093...105,170,761
Ensembl chr 3:104,816,987...105,086,436
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 affects expression EXP triptolide affects the expression of FMO5 protein CTD PMID:32519852 NCBI chr 2:199,796,870...199,823,927
Ensembl chr 2:199,796,881...199,823,927
JBrowse link
G Fnip2 folliculin interacting protein 2 decreases expression ISO triptolide results in decreased expression of FNIP2 mRNA CTD PMID:32835833 NCBI chr 2:178,223,561...178,334,925
Ensembl chr 2:178,225,915...178,334,900
JBrowse link
G Foxo3 forkhead box O3 decreases phosphorylation ISO triptolide results in decreased phosphorylation of FOXO3 protein CTD PMID:32061799 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
G Foxp3 forkhead box P3 decreases expression ISO triptolide results in decreased expression of FOXP3 mRNA CTD PMID:24949944 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G Frmd4b FERM domain containing 4B decreases expression ISO triptolide results in decreased expression of FRMD4B mRNA CTD PMID:32835833 NCBI chr 4:129,658,137...129,984,735
Ensembl chr 4:129,658,840...129,846,642
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression EXP triptolide results in increased expression of FTH1 protein CTD PMID:32519852 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Ftl1 ferritin light chain 1 increases expression EXP triptolide results in increased expression of FTL1 protein CTD PMID:32519852 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G Fubp1 far upstream element binding protein 1 increases expression ISO triptolide results in increased expression of FUBP1 mRNA CTD PMID:32835833 NCBI chr 2:257,425,676...257,452,745
Ensembl chr 2:257,425,679...257,449,568
JBrowse link
G Fundc2 FUN14 domain containing 2 decreases expression EXP triptolide results in decreased expression of FUNDC2 protein CTD PMID:32519852 NCBI chr18:401,878...407,954
Ensembl chr18:402,295...407,954
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase multiple interactions
increases expression
EXP Lithium Chloride inhibits the reaction [triptolide results in increased expression of FYN protein] CTD PMID:30926361 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression
multiple interactions
EXP
ISO
triptolide results in decreased expression of G6PC1 mRNA
triptolide results in decreased expression of G6PC mRNA
Lipopolysaccharides promotes the reaction [triptolide results in decreased expression of G6PC mRNA]; triptolide promotes the reaction [Lipopolysaccharides results in decreased expression of G6PC mRNA]
CTD PMID:23639586 PMID:30633930 PMID:32835833 NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression ISO triptolide results in increased expression of G6PDX mRNA CTD PMID:32835833 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gaa alpha glucosidase increases expression EXP triptolide results in increased expression of GAA protein CTD PMID:32519852 NCBI chr10:108,395,873...108,412,999
Ensembl chr10:108,395,860...108,413,059
JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 decreases expression ISO triptolide results in decreased expression of GABBR2 mRNA CTD PMID:32835833 NCBI chr 5:62,276,100...62,621,737
Ensembl chr 5:62,276,100...62,621,737
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression ISO triptolide results in increased expression of GADD45B mRNA CTD PMID:32835833 NCBI chr 7:11,646,283...11,648,338
Ensembl chr 7:11,646,269...11,648,322
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma decreases expression EXP triptolide results in decreased expression of GADD45G mRNA CTD PMID:23639586 NCBI chr17:13,391,474...13,393,219
Ensembl chr17:13,391,467...13,393,243
JBrowse link
G Gal3st1 galactose-3-O-sulfotransferase 1 decreases expression ISO triptolide results in decreased expression of GAL3ST1 mRNA CTD PMID:32835833 NCBI chr14:84,231,473...84,247,371
Ensembl chr14:84,231,639...84,247,369
JBrowse link
G Galk1 galactokinase 1 decreases expression ISO triptolide results in decreased expression of GALK1 mRNA CTD PMID:32835833 NCBI chr10:104,560,322...104,564,499
Ensembl chr10:104,560,303...104,564,480
JBrowse link
G Galm galactose mutarotase decreases expression EXP triptolide results in decreased expression of GALM mRNA CTD PMID:23639586 NCBI chr 6:2,808,988...2,860,742
Ensembl chr 6:2,808,841...2,860,744
JBrowse link
G Galnt11 polypeptide N-acetylgalactosaminyltransferase 11 increases expression EXP triptolide results in increased expression of GALNT11 protein CTD PMID:32519852 NCBI chr 4:6,297,255...6,330,765
Ensembl chr 4:6,297,258...6,330,765
JBrowse link
G Galnt3 polypeptide N-acetylgalactosaminyltransferase 3 increases expression EXP triptolide results in increased expression of GALNT3 protein CTD PMID:32519852 NCBI chr 3:52,174,469...52,212,395
Ensembl chr 3:52,175,547...52,212,412
JBrowse link
G Galnt7 polypeptide N-acetylgalactosaminyltransferase 7 increases expression EXP triptolide results in increased expression of GALNT7 protein CTD PMID:32519852 NCBI chr16:35,935,059...36,062,734
Ensembl chr16:35,934,970...36,062,719
JBrowse link
G Gamt guanidinoacetate N-methyltransferase decreases expression ISO triptolide results in decreased expression of GAMT mRNA CTD PMID:32835833 NCBI chr 7:12,314,848...12,317,998
Ensembl chr 7:12,314,848...12,317,998
JBrowse link
G Gas1 growth arrest-specific 1 decreases expression ISO triptolide results in decreased expression of GAS1 mRNA CTD PMID:32835833 NCBI chr17:4,846,116...4,849,350
Ensembl chr17:4,846,789...4,847,940
JBrowse link
G Gas2l1 growth arrest-specific 2 like 1 increases expression ISO triptolide results in increased expression of GAS2L1 mRNA CTD PMID:32835833 NCBI chr14:85,308,443...85,318,475
Ensembl chr14:85,308,443...85,318,194
JBrowse link
G Gask1a golgi associated kinase 1A decreases expression ISO triptolide results in decreased expression of FAM198A mRNA CTD PMID:32835833 NCBI chr 8:130,581,072...130,614,118
Ensembl chr 8:130,581,062...130,612,510
JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 decreases expression ISO triptolide results in decreased expression of GBE1 mRNA CTD PMID:32835833 NCBI chr11:7,210,169...7,485,895
Ensembl chr11:7,210,209...7,485,890
JBrowse link
G Gbp2 guanylate binding protein 2 increases expression EXP triptolide results in increased expression of GBP2 protein CTD PMID:32519852 NCBI chr 2:248,276,795...248,293,784
Ensembl chr 2:248,276,709...248,293,784
JBrowse link
G Gck glucokinase decreases expression EXP triptolide results in decreased expression of GCK mRNA CTD PMID:23639586 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression
multiple interactions
ISO
EXP
triptolide results in decreased expression of GCLC protein
NFE2L2 protein inhibits the reaction [triptolide results in decreased expression of GCLC protein]
CTD PMID:25169008 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gdf9 growth differentiation factor 9 increases expression ISO triptolide results in increased expression of GDF9 mRNA CTD PMID:32835833 NCBI chr10:38,782,519...38,793,238
Ensembl chr10:38,788,992...38,792,940
JBrowse link
G Gimap4 GTPase, IMAP family member 4 increases expression EXP triptolide results in increased expression of GIMAP4 protein CTD PMID:32519852 NCBI chr 4:78,320,230...78,327,144
Ensembl chr 4:78,320,190...78,327,144
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression
multiple interactions
ISO triptolide results in decreased expression of GJA1 mRNA; triptolide results in decreased expression of GJA1 protein
10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [triptolide results in decreased expression of GJA1 mRNA]; 10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [triptolide results in decreased expression of GJA1 protein]
CTD PMID:30836114 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Glmp glycosylated lysosomal membrane protein decreases expression EXP triptolide results in decreased expression of GLMP protein CTD PMID:32519852 NCBI chr 2:187,697,528...187,701,118
Ensembl chr 2:187,697,523...187,701,118
JBrowse link
G Gls glutaminase increases expression ISO triptolide results in increased expression of GLS mRNA CTD PMID:32835833 NCBI chr 9:54,212,622...54,284,879
Ensembl chr 9:54,212,767...54,284,872
JBrowse link
G Gmds GDP-mannose 4, 6-dehydratase increases expression EXP triptolide results in increased expression of GMDS protein CTD PMID:32519852 NCBI chr17:33,408,722...33,938,086
Ensembl chr17:33,408,722...33,938,085
JBrowse link
G Gnmt glycine N-methyltransferase decreases expression ISO triptolide results in decreased expression of GNMT mRNA CTD PMID:32835833 NCBI chr 9:16,565,274...16,568,626
Ensembl chr 9:16,565,225...16,568,627
JBrowse link
G Gon4l gon-4 like increases expression ISO triptolide results in increased expression of GON4L mRNA CTD PMID:32835833 NCBI chr 2:188,139,730...188,212,902
Ensembl chr 2:188,139,730...188,215,723
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 decreases expression ISO triptolide results in decreased expression of GOT1 mRNA CTD PMID:32835833 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Gp5 glycoprotein V (platelet) increases expression ISO triptolide results in increased expression of GP5 mRNA CTD PMID:32835833 NCBI chr11:73,015,380...73,017,570
Ensembl chr11:73,015,387...73,017,090
Ensembl chr11:73,015,387...73,017,090
Ensembl chr11:73,015,387...73,017,090
Ensembl chr11:73,015,387...73,017,090
JBrowse link
G Gpaa1 glycosylphosphatidylinositol anchor attachment 1 increases expression EXP triptolide results in increased expression of GPAA1 protein CTD PMID:32519852 NCBI chr 7:117,394,367...117,397,950
Ensembl chr 7:117,394,372...117,397,956
JBrowse link
G Gpkow G patch domain and KOW motifs increases expression ISO triptolide results in increased expression of GPKOW mRNA CTD PMID:32835833 NCBI chr  X:15,636,567...15,651,332
Ensembl chr  X:15,636,563...15,651,332
JBrowse link
G Gpr12 G protein-coupled receptor 12 decreases expression ISO triptolide results in decreased expression of GPR12 mRNA CTD PMID:32835833 NCBI chr12:10,253,710...10,257,135
Ensembl chr12:10,254,951...10,257,130
JBrowse link
G Gpr146 G protein-coupled receptor 146 decreases expression ISO triptolide results in decreased expression of GPR146 mRNA CTD PMID:32835833 NCBI chr12:17,343,396...17,358,631
Ensembl chr12:17,345,510...17,358,617
JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity
multiple interactions
increases expression
ISO
EXP
triptolide results in increased activity of GPT protein
[Atorvastatin co-treated with triptolide] results in increased expression of GPT protein
triptolide results in increased expression of GPT protein
catalpol inhibits the reaction [triptolide results in increased expression of GPT protein]; catalpol promotes the reaction [Saponins inhibits the reaction [triptolide results in increased expression of GPT protein]]; NFE2L2 protein affects the reaction [catalpol promotes the reaction [Saponins inhibits the reaction [triptolide results in increased expression of GPT protein]]]; NFE2L2 protein affects the reaction [Saponins promotes the reaction [catalpol inhibits the reaction [triptolide results in increased expression of GPT protein]]]; NFE2L2 protein affects the reaction [triptolide results in increased expression of GPT protein]; Saponins inhibits the reaction [triptolide results in increased expression of GPT protein]; Saponins promotes the reaction [catalpol inhibits the reaction [triptolide results in increased expression of GPT protein]]
ABCB1A mutant form promotes the reaction [triptolide results in increased activity of GPT protein]
CTD PMID:23836259 PMID:26134275 PMID:30682494 PMID:32987112 PMID:33600922 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
increases expression
ISO
EXP
Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX1 mRNA]
triptolide results in increased expression of GPX1 protein
CTD PMID:31241159 PMID:32519852 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions
increases expression
ISO Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX2 mRNA] CTD PMID:31241159 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
JBrowse link
G Gpx3 glutathione peroxidase 3 multiple interactions
increases expression
ISO Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX3 mRNA] CTD PMID:31241159 NCBI chr10:40,247,436...40,255,423
Ensembl chr10:40,247,436...40,255,422
JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression
multiple interactions
ISO triptolide results in increased expression of GPX4 mRNA
Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX4 mRNA]
CTD PMID:31241159 NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154
JBrowse link
G Grb2 growth factor receptor bound protein 2 decreases expression ISO triptolide results in decreased expression of GRB2 protein CTD PMID:26420756 NCBI chr10:104,193,953...104,263,071
Ensembl chr10:104,193,955...104,263,071
JBrowse link
G Grem2 gremlin 2, DAN family BMP antagonist decreases expression ISO triptolide results in decreased expression of GREM2 mRNA CTD PMID:32835833 NCBI chr13:92,894,431...92,988,137
Ensembl chr13:92,894,431...92,988,137
JBrowse link
G Grhl1 grainyhead-like transcription factor 1 increases expression ISO triptolide results in increased expression of GRHL1 mRNA CTD PMID:32835833 NCBI chr 6:43,734,837...43,795,757
Ensembl chr 6:43,743,702...43,794,342
JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 increases expression ISO triptolide results in increased expression of GRIK5 mRNA CTD PMID:32835833 NCBI chr 1:81,885,516...81,946,731
Ensembl chr 1:81,885,521...81,946,714
JBrowse link
G Grwd1 glutamate-rich WD repeat containing 1 increases expression ISO triptolide results in increased expression of GRWD1 mRNA CTD PMID:32835833 NCBI chr 1:101,813,356...101,819,058
Ensembl chr 1:101,813,684...101,819,478
JBrowse link
G Gsdmd gasdermin D increases expression EXP triptolide results in increased expression of GSDMD protein CTD PMID:32519852 NCBI chr 7:116,889,147...116,894,134
Ensembl chr 7:116,889,572...116,894,134
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases phosphorylation
EXP Lithium Chloride inhibits the reaction [triptolide results in increased phosphorylation of GSK3B protein] CTD PMID:30926361 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 decreases expression ISO triptolide results in decreased expression of GSTA3 mRNA CTD PMID:32835833 NCBI chr 9:27,357,490...27,417,023
Ensembl chr 9:27,402,381...27,417,023
JBrowse link
G Gtf2f1 general transcription factor IIF subunit 1 increases expression ISO triptolide results in increased expression of GTF2F1 mRNA CTD PMID:32835833 NCBI chr 9:10,032,806...10,042,392
Ensembl chr 9:10,033,011...10,042,418
JBrowse link
G Gtpbp4 GTP binding protein 4 increases expression ISO triptolide results in increased expression of GTPBP4 mRNA CTD PMID:32835833 NCBI chr17:63,111,086...63,145,618
Ensembl chr17:63,110,254...63,145,577
JBrowse link
G Gtse1 G-2 and S-phase expressed 1 increases expression ISO triptolide results in increased expression of GTSE1 mRNA CTD PMID:32835833 NCBI chr 7:126,736,416...126,753,221
Ensembl chr 7:126,736,732...126,753,220
JBrowse link
G Gusb glucuronidase, beta multiple interactions
decreases activity
ISO resveratrol inhibits the reaction [triptolide results in decreased activity of GUSB protein] CTD PMID:29723566 NCBI chr12:30,202,066...30,215,583
Ensembl chr12:30,198,822...30,227,771
JBrowse link
G Gys2 glycogen synthase 2 decreases expression ISO triptolide results in decreased expression of GYS2 mRNA CTD PMID:32835833 NCBI chr 4:176,638,632...176,679,805
Ensembl chr 4:176,638,629...176,679,815
JBrowse link
G H1f4 H1.4 linker histone, cluster member increases expression ISO triptolide results in increased expression of H1F4 mRNA CTD PMID:32835833 NCBI chr17:43,734,461...43,735,120
Ensembl chr17:43,734,461...43,735,120
JBrowse link
G H2ax H2A.X variant histone increases expression ISO triptolide results in increased expression of H2AX mRNA CTD PMID:32835833 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G H2bu1 H2B.U histone 1 increases expression ISO triptolide results in increased expression of H2BC21 mRNA; triptolide results in increased expression of H2BC6 mRNA CTD PMID:32835833 NCBI chr10:45,296,638...45,297,385
Ensembl chr10:45,296,638...45,297,385
JBrowse link
G H4c3 H4 clustered histone 3 increases expression ISO triptolide results in increased expression of H4C3 mRNA CTD PMID:32835833 NCBI chr 4:170,144,871...170,145,311
Ensembl chr 4:170,144,951...170,145,262
JBrowse link
G H4f16 H4 histone 16 increases expression ISO triptolide results in increased expression of H4F16 mRNA CTD PMID:32835833 NCBI chr17:43,821,122...43,821,587 JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase decreases expression ISO triptolide results in decreased expression of HAAO mRNA CTD PMID:32835833 NCBI chr 6:7,045,145...7,059,227
Ensembl chr 6:7,045,152...7,058,314
JBrowse link
G Hao1 hydroxyacid oxidase 1 decreases expression ISO triptolide results in decreased expression of HAO1 mRNA CTD PMID:32835833 NCBI chr 3:127,444,900...127,500,709
Ensembl chr 3:127,444,902...127,500,709
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 increases expression EXP triptolide results in increased expression of HBA-A2 protein; triptolide results in increased expression of HBA1 protein CTD PMID:32519852 NCBI chr10:15,589,364...15,590,207
Ensembl chr10:15,589,364...15,590,220
JBrowse link
G Hbb hemoglobin subunit beta increases expression EXP triptolide results in increased expression of HBB protein CTD PMID:32519852 NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725
JBrowse link
G Hdac1 histone deacetylase 1 increases expression EXP triptolide results in increased expression of HDAC1 mRNA CTD PMID:23639586 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Hdac1l histone deacetylase 1-like increases expression EXP triptolide results in increased expression of HDAC1L protein CTD PMID:32519852 NCBI chr 9:84,893,145...84,894,599
Ensembl chr 9:84,893,145...84,894,599
JBrowse link
G Hdac2 histone deacetylase 2 increases expression EXP triptolide results in increased expression of HDAC2 protein CTD PMID:32519852 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198
JBrowse link
G Hdac6 histone deacetylase 6 increases expression ISO triptolide results in increased expression of HDAC6 mRNA; triptolide results in increased expression of HDAC6 protein CTD PMID:32061799 NCBI chr  X:15,396,185...15,417,486
Ensembl chr  X:15,295,473...15,316,671
Ensembl chr  X:15,295,473...15,316,671
JBrowse link
G Herc6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 increases expression EXP triptolide results in increased expression of HERC6 protein CTD PMID:32519852 NCBI chr 4:88,606,851...88,649,424
Ensembl chr 4:88,607,518...88,649,216
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 decreases expression ISO triptolide results in decreased expression of HERPUD1 mRNA CTD PMID:32835833 NCBI chr19:11,046,905...11,057,440
Ensembl chr19:11,046,909...11,057,254
JBrowse link
G Hes1 hes family bHLH transcription factor 1 decreases expression
increases expression
multiple interactions
ISO triptolide results in decreased expression of HES1 protein
triptolide results in increased expression of HES1 mRNA
triptolide results in decreased expression of HES1 mRNA; triptolide results in decreased expression of HES1 protein
Fenofibrate inhibits the reaction [triptolide results in increased expression of HES1 mRNA]; NOTCH1 protein modified form inhibits the reaction [triptolide results in decreased expression of HES1 protein]
CTD PMID:30394310 PMID:31241159 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hes6 hes family bHLH transcription factor 6 decreases expression ISO triptolide results in decreased expression of HES6 mRNA CTD PMID:32835833 NCBI chr 9:98,549,698...98,551,438
Ensembl chr 9:98,549,705...98,551,438
JBrowse link
G Hexim1 HEXIM P-TEFb complex subunit 1 increases expression ISO triptolide results in increased expression of HEXIM1 mRNA CTD PMID:32835833 NCBI chr10:91,200,874...91,202,986
Ensembl chr10:91,200,874...91,202,984
JBrowse link
G Higd2al1 HIG1 hypoxia inducible domain family, member 2A-like 1 increases expression EXP triptolide results in increased expression of HIGD2AL1 protein CTD PMID:32519852 NCBI chr12:4,546,240...4,546,871 JBrowse link
G Hikeshi heat shock protein nuclear import factor increases expression EXP triptolide results in increased expression of HIKESHI protein CTD PMID:32519852 NCBI chr 1:154,147,098...154,170,429
Ensembl chr 1:154,142,836...154,170,409
JBrowse link
G Hist1h2ail1 histone cluster 1 H2a family member I like 1 increases expression ISO triptolide results in increased expression of H3C6 mRNA CTD PMID:32835833 NCBI chr17:43,814,773...43,815,183
Ensembl chr17:43,814,773...43,815,183
JBrowse link
G Hist2h3c2 histone cluster 2 H3 family member C2 increases expression ISO triptolide results in increased expression of H3C11 mRNA CTD PMID:32835833 NCBI chr 2:198,390,024...198,418,075
Ensembl chr 2:198,417,619...198,418,029
JBrowse link
G Hist2h4 histone cluster 2, H4 increases expression ISO triptolide results in increased expression of H4C11 mRNA CTD PMID:32835833 NCBI chr 2:198,411,955...198,412,350
Ensembl chr 2:198,411,955...198,412,350
JBrowse link
G Hist2h4a histone cluster 2 H4 family member A increases expression ISO triptolide results in increased expression of H4C8 mRNA CTD PMID:32835833 NCBI chr 4:170,800,539...170,800,979
Ensembl chr17:43,770,250...43,770,561
Ensembl chr17:43,770,250...43,770,561
Ensembl chr17:43,770,250...43,770,561
Ensembl chr17:43,770,250...43,770,561
Ensembl chr 2:43,770,250...43,770,561
Ensembl chr17:43,770,250...43,770,561
Ensembl chr17:43,770,250...43,770,561
Ensembl chr17:43,770,250...43,770,561
Ensembl chr 4:43,770,250...43,770,561
Ensembl chr 4:43,770,250...43,770,561
Ensembl chr 4:43,770,250...43,770,561
Ensembl chr 4:43,770,250...43,770,561
JBrowse link
G Hist3h2a histone cluster 3, H2a increases expression ISO triptolide results in increased expression of H2AC6 mRNA CTD PMID:32835833 NCBI chr10:45,297,603...45,299,155 JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions ISO [Colforsin co-treated with triptolide] results in decreased expression of HMGCR mRNA CTD PMID:31557376 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression ISO triptolide results in decreased expression of HMGCS1 mRNA CTD PMID:32835833 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
affects expression
decreases expression
EXP
ISO
triptolide results in increased expression of HMOX1 mRNA
10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [triptolide results in decreased expression of HMOX1 mRNA]; 10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [triptolide results in decreased expression of HMOX1 protein]
[triptolide co-treated with catalpol co-treated with Saponins] results in increased expression of HMOX1 protein; [triptolide co-treated with catalpol] results in increased expression of HMOX1 protein; [triptolide co-treated with Saponins] results in increased expression of HMOX1 protein
NFE2L2 protein inhibits the reaction [triptolide results in decreased expression of HMOX1 protein]
triptolide affects the expression of HMOX1 mRNA
triptolide results in decreased expression of HMOX1 mRNA; triptolide results in decreased expression of HMOX1 protein
CTD PMID:23639586 PMID:25169008 PMID:30682494 PMID:30836114 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnmt histamine N-methyltransferase decreases expression ISO triptolide results in decreased expression of HNMT mRNA CTD PMID:32835833 NCBI chr 3:905,111...937,038
Ensembl chr 3:904,765...937,102
JBrowse link
G Hp haptoglobin increases expression EXP triptolide results in increased expression of HP protein CTD PMID:32519852 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Hpd 4-hydroxyphenylpyruvate dioxygenase decreases expression ISO triptolide results in decreased expression of HPD mRNA CTD PMID:32835833 NCBI chr12:38,828,606...38,839,956
Ensembl chr12:38,828,444...38,839,969
JBrowse link
G Hpx hemopexin increases expression EXP triptolide results in increased expression of HPX protein CTD PMID:32519852 NCBI chr 1:170,423,558...170,431,066
Ensembl chr 1:170,423,483...170,431,073
JBrowse link
G Hras HRas proto-oncogene, GTPase decreases expression EXP triptolide results in decreased expression of HRAS mRNA CTD PMID:23639586 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Hrg histidine-rich glycoprotein increases expression
decreases expression
EXP
ISO
triptolide results in increased expression of HRG protein
triptolide results in decreased expression of HRG mRNA
CTD PMID:32519852 PMID:32835833 NCBI chr11:81,621,274...81,639,938
Ensembl chr11:81,621,283...81,639,952
JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 multiple interactions ISO [Colforsin co-treated with triptolide] results in decreased expression of HSD3B2 mRNA CTD PMID:31557376 NCBI chr 2:200,712,895...200,722,429
Ensembl chr 2:202,341,422...202,350,929
JBrowse link
G Hsf2bp heat shock transcription factor 2 binding protein increases expression ISO triptolide results in increased expression of HSF2BP mRNA CTD PMID:32835833 NCBI chr20:10,757,172...10,844,177
Ensembl chr20:10,757,854...10,844,178
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression ISO triptolide results in increased expression of HSP90AA1 mRNA CTD PMID:32835833 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A decreases response to substance ISO HSPA1A results in decreased susceptibility to triptolide CTD PMID:19546256 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression EXP triptolide results in increased expression of HSPA1B protein CTD PMID:32519852 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 increases expression EXP triptolide results in increased expression of HSPA2 protein CTD PMID:32519852 NCBI chr 6:99,433,575...99,436,288
Ensembl chr 6:99,433,550...99,436,289
JBrowse link
G Hspa4l heat shock protein family A (Hsp70) member 4 like affects expression ISO triptolide affects the expression of HSPA4L mRNA CTD PMID:32835833 NCBI chr 2:127,625,737...127,682,864
Ensembl chr 2:127,625,683...127,677,503
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression ISO triptolide results in decreased expression of HSPA5 protein CTD PMID:26990902 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression EXP triptolide results in decreased expression of HSPD1 protein CTD PMID:32519852 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Htra4 HtrA serine peptidase 4 decreases expression ISO triptolide results in decreased expression of HTRA4 mRNA CTD PMID:32835833 NCBI chr16:71,784,819...71,802,765
Ensembl chr16:71,787,966...71,802,763
JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression
increases expression
multiple interactions
ISO triptolide results in decreased expression of ICAM1 mRNA; triptolide results in decreased expression of ICAM1 protein
triptolide results in increased expression of ICAM1 mRNA; triptolide results in increased expression of ICAM1 protein
TRAJ18 protein affects the reaction [triptolide results in increased expression of ICAM1 protein]
CTD PMID:17931847 PMID:32835833 PMID:32987112 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression ISO triptolide results in decreased expression of IDI1 mRNA CTD PMID:32835833 NCBI chr17:57,976,266...57,984,036
Ensembl chr17:57,976,268...57,984,036
JBrowse link
G Idua alpha-L-iduronidase increases expression ISO triptolide results in increased expression of IDUA mRNA CTD PMID:32835833 NCBI chr14:2,041,828...2,056,762
Ensembl chr14:2,042,411...2,056,762
JBrowse link
G Ier5 immediate early response 5 increases expression ISO triptolide results in increased expression of IER5 mRNA CTD PMID:32835833 NCBI chr13:72,742,210...72,744,302
Ensembl chr13:72,742,210...72,744,303
JBrowse link
G Ifit1bl interferon-induced protein with tetratricopeptide repeats 1B-like increases expression EXP triptolide results in increased expression of IFIT1 protein CTD PMID:32519852 NCBI chr 1:252,914,684...252,959,348
Ensembl chr 1:252,914,684...252,922,486
JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 increases expression EXP triptolide results in increased expression of IFIT2 protein CTD PMID:32519852 NCBI chr 1:252,894,663...252,900,727
Ensembl chr 1:252,894,663...252,900,726
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 increases expression EXP triptolide results in increased expression of IFIT3 protein CTD PMID:32519852 NCBI chr 1:252,906,234...252,911,377
Ensembl chr 1:252,906,234...252,911,382
JBrowse link
G Ifng interferon gamma multiple interactions ISO triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of [IL12A protein binds to IL12B protein]]; triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CD80 protein]; triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CD86 protein]; triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein] CTD PMID:15663903 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 increases expression EXP triptolide results in increased expression of IGDCC3 protein CTD PMID:32519852 NCBI chr 8:70,630,546...70,685,882
Ensembl chr 8:70,630,767...70,684,115
JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression ISO triptolide results in decreased expression of IGF1 mRNA CTD PMID:32835833 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf2bp3 insulin-like growth factor 2 mRNA binding protein 3 decreases expression ISO triptolide results in decreased expression of IGF2BP3 mRNA CTD PMID:32835833 NCBI chr 4:78,744,683...78,879,457
Ensembl chr 4:78,746,547...78,879,294
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 decreases expression EXP
ISO
triptolide results in decreased expression of IGFBP1 mRNA CTD PMID:23639586 PMID:32835833 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 decreases expression ISO triptolide results in decreased expression of IGFBP4 mRNA CTD PMID:32835833 NCBI chr10:86,950,555...86,962,563
Ensembl chr10:86,950,557...86,962,578
JBrowse link
G IgG-2a gamma-2a immunoglobulin heavy chain increases expression EXP triptolide results in increased expression of IGG-2A protein CTD PMID:32519852
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions
decreases phosphorylation
ISO
EXP
TRP53 protein affects the reaction [triptolide results in decreased phosphorylation of IKBKB protein]
pifithrin inhibits the reaction [triptolide results in decreased phosphorylation of IKBKB protein]
CTD PMID:31618665 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Il12a interleukin 12A multiple interactions ISO triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of [IL12A protein binds to IL12B protein]] CTD PMID:15663903 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
JBrowse link
G Il12b interleukin 12B multiple interactions ISO triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of [IL12A protein binds to IL12B protein]]; triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein] CTD PMID:15663903 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il17a interleukin 17A multiple interactions
increases expression
ISO IL17A protein promotes the reaction [triptolide results in increased expression of CCL11 mRNA]; IL17A protein promotes the reaction [triptolide results in increased expression of CXCL1 mRNA]; IL17A protein promotes the reaction [triptolide results in increased expression of CXCL2 mRNA]; IL17A protein promotes the reaction [triptolide results in increased expression of FASL mRNA]; IL17A protein promotes the reaction [triptolide results in increased expression of IL1B mRNA]
triptolide results in increased expression of IL17A mRNA; triptolide results in increased expression of IL17A protein
CTD PMID:24949944 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il18 interleukin 18 decreases expression ISO triptolide results in decreased expression of IL18 mRNA CTD PMID:32835833 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
ISO Fenofibrate inhibits the reaction [triptolide results in increased expression of IL1B mRNA]; IL17A protein promotes the reaction [triptolide results in increased expression of IL1B mRNA]; triptolide promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] CTD PMID:24949944 PMID:30633930 PMID:31241159 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il4 interleukin 4 increases secretion ISO triptolide results in increased secretion of IL4 protein CTD PMID:32987112 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO Fenofibrate inhibits the reaction [triptolide results in increased expression of IL6 mRNA]; triptolide promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] CTD PMID:30633930 PMID:31241159 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Imp4 IMP U3 small nucleolar ribonucleoprotein 4 increases expression ISO triptolide results in increased expression of IMP4 mRNA CTD PMID:32835833 NCBI chr 9:37,769,959...37,775,097
Ensembl chr 9:37,769,959...37,775,154
JBrowse link
G Impa2 inositol monophosphatase 2 decreases expression ISO triptolide results in decreased expression of IMPA2 mRNA CTD PMID:32835833 NCBI chr18:63,016,577...63,050,123
Ensembl chr18:63,016,577...63,047,781
JBrowse link
G Impdh2 inosine monophosphate dehydrogenase 2 increases expression ISO triptolide results in increased expression of IMPDH2 mRNA CTD PMID:32835833 NCBI chr 8:117,346,983...117,351,619
Ensembl chr 8:117,347,029...117,351,610
JBrowse link
G Inava innate immunity activator increases expression ISO triptolide results in increased expression of INAVA mRNA CTD PMID:32835833 NCBI chr13:53,088,438...53,108,713
Ensembl chr13:53,088,439...53,108,713
JBrowse link
G Inca1 inhibitor of CDK, cyclin A1 interacting protein 1 affects expression ISO triptolide affects the expression of INCA1 mRNA CTD PMID:32835833 NCBI chr10:57,309,722...57,322,140
Ensembl chr10:57,309,972...57,317,985
JBrowse link
G Inka2 inka box actin regulator 2 increases expression ISO triptolide results in increased expression of FAM212B mRNA CTD PMID:32835833 NCBI chr 2:208,170,652...208,187,088
Ensembl chr 2:208,170,652...208,185,965
JBrowse link
G Inmt indolethylamine N-methyltransferase decreases expression ISO triptolide results in decreased expression of INMT mRNA CTD PMID:32835833 NCBI chr 4:85,381,907...85,386,203
Ensembl chr 4:85,381,889...85,386,231
JBrowse link
G Insc INSC, spindle orientation adaptor protein affects expression ISO triptolide affects the expression of INSC mRNA CTD PMID:32835833 NCBI chr 1:184,299,200...184,407,487
Ensembl chr 1:184,299,250...184,407,480
JBrowse link
G Insig1 insulin induced gene 1 decreases expression ISO triptolide results in decreased expression of INSIG1 mRNA CTD PMID:32835833 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Insr insulin receptor increases expression EXP triptolide results in increased expression of INSR protein CTD PMID:32519852 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414
JBrowse link
G Ints2 integrator complex subunit 2 increases expression ISO triptolide results in increased expression of INTS2 mRNA CTD PMID:32835833 NCBI chr10:73,632,805...73,690,952
Ensembl chr10:73,634,255...73,690,887
JBrowse link
G Ipo13 importin 13 increases expression ISO triptolide results in increased expression of IPO13 mRNA CTD PMID:32835833 NCBI chr 5:136,728,744...136,749,187
Ensembl chr 5:136,728,740...136,748,980
JBrowse link
G Irgm immunity-related GTPase M increases expression EXP triptolide results in increased expression of IRGM protein CTD PMID:32519852 NCBI chr10:34,213,885...34,221,968
Ensembl chr10:34,213,936...34,221,928
JBrowse link
G Irs1 insulin receptor substrate 1 increases degradation
multiple interactions
ISO triptolide results in increased degradation of IRS1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [triptolide results in decreased expression of IRS1 protein]; triptolide results in decreased expression of and results in decreased phosphorylation of IRS1 protein
CTD PMID:32061799 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Isca1 iron-sulfur cluster assembly 1 decreases expression EXP triptolide results in decreased expression of ISCA1 protein CTD PMID:32519852 NCBI chr17:5,281,727...5,294,386
Ensembl chr17:5,281,727...5,294,384
JBrowse link
G Iscu iron-sulfur cluster assembly enzyme decreases expression EXP triptolide results in decreased expression of ISCU protein CTD PMID:32519852 NCBI chr12:48,621,454...48,627,297
Ensembl chr12:48,621,454...48,627,297
JBrowse link
G Isyna1 inositol-3-phosphate synthase 1 increases expression EXP triptolide results in increased expression of ISYNA1 protein CTD PMID:32519852 NCBI chr16:20,589,497...20,592,333
Ensembl chr16:20,589,481...20,592,449
JBrowse link
G Itga5 integrin subunit alpha 5 increases expression EXP
ISO
triptolide results in increased expression of ITGA5 protein
triptolide results in increased expression of ITGA5 mRNA
CTD PMID:32519852 PMID:32835833 NCBI chr 7:144,970,444...144,993,652
Ensembl chr 7:144,970,444...144,993,652
JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 increases expression EXP triptolide results in increased expression of ITIH3 protein CTD PMID:32519852 NCBI chr16:6,983,779...7,007,288
Ensembl chr16:6,992,062...7,007,287
JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 increases expression EXP triptolide results in increased expression of ITIH4 protein CTD PMID:32519852 NCBI chr16:6,970,367...6,985,538
Ensembl chr16:6,970,342...6,985,579
JBrowse link
G Itpr3 inositol 1,4,5-trisphosphate receptor, type 3 increases expression EXP triptolide results in increased expression of ITPR3 protein CTD PMID:32519852 NCBI chr20:5,645,894...5,711,702
Ensembl chr20:5,646,097...5,711,702
JBrowse link
G Jph1 junctophilin 1 decreases expression ISO triptolide results in decreased expression of JPH1 mRNA CTD PMID:32835833 NCBI chr 5:1,417,414...1,511,754
Ensembl chr 5:1,417,478...1,511,416
JBrowse link
G Jpt1 Jupiter microtubule associated homolog 1 increases expression ISO triptolide results in increased expression of HN1 mRNA CTD PMID:32835833 NCBI chr10:104,057,739...104,075,776
Ensembl chr10:104,057,697...104,075,777
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO triptolide results in increased expression of JUN mRNA CTD PMID:32835833 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kctd18 potassium channel tetramerization domain containing 18 increases expression ISO triptolide results in increased expression of KCTD18 mRNA CTD PMID:32835833 NCBI chr 9:64,849,547...64,916,652
Ensembl chr 9:64,852,289...64,916,652
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases expression ISO triptolide results in decreased expression of KEAP1 protein CTD PMID:30682494 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Khsrp KH-type splicing regulatory protein decreases expression EXP triptolide results in decreased expression of KHSRP protein CTD PMID:32519852 NCBI chr 9:10,013,795...10,023,670
Ensembl chr 9:10,013,854...10,022,924
JBrowse link
G Kif20a kinesin family member 20A increases expression ISO triptolide results in increased expression of KIF20A mRNA CTD PMID:32835833 NCBI chr18:27,424,328...27,432,814
Ensembl chr18:27,424,328...27,432,814
JBrowse link
G Kif21a kinesin family member 21A increases expression EXP triptolide results in increased expression of KIF21A protein CTD PMID:32519852 NCBI chr 7:132,069,962...132,200,947
Ensembl chr 7:132,071,116...132,143,470
JBrowse link
G Kifc3 kinesin family member C3 increases expression ISO triptolide results in increased expression of KIFC3 mRNA CTD PMID:32835833 NCBI chr19:10,305,405...10,339,186
Ensembl chr19:10,320,604...10,339,178
JBrowse link
G Klc1 kinesin light chain 1 increases expression ISO triptolide results in increased expression of KLC1 mRNA CTD PMID:32835833 NCBI chr 6:136,330,151...136,373,716
Ensembl chr 6:136,330,383...136,373,721
JBrowse link
G Klhl26 kelch-like family member 26 increases expression ISO triptolide results in increased expression of KLHL26 mRNA CTD PMID:32835833 NCBI chr16:20,704,807...20,729,882
Ensembl chr16:20,704,807...20,729,882
JBrowse link
G Klkb1 kallikrein B1 decreases expression ISO triptolide results in decreased expression of KLKB1 mRNA CTD PMID:32835833 NCBI chr16:50,151,127...50,175,407
Ensembl chr16:50,152,008...50,175,458
JBrowse link
G Kng2 kininogen 2 increases expression EXP triptolide results in increased expression of KNG1 protein; triptolide results in increased expression of MAP1 protein CTD PMID:32519852 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Kras KRAS proto-oncogene, GTPase increases expression EXP triptolide results in increased expression of KRAS mRNA CTD PMID:23639586 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Kyat1 kynurenine aminotransferase 1 decreases expression ISO triptolide results in decreased expression of KYAT1 mRNA CTD PMID:32835833 NCBI chr 3:8,752,289...8,785,617
Ensembl chr 3:8,752,625...8,766,433
JBrowse link
G Kyat3 kynurenine aminotransferase 3 decreases expression ISO triptolide results in decreased expression of KYAT3 mRNA CTD PMID:32835833 NCBI chr 2:248,644,473...248,690,289
Ensembl chr 2:248,649,441...248,690,089
JBrowse link
G L1cam L1 cell adhesion molecule increases expression EXP triptolide results in increased expression of L1CAM protein CTD PMID:32519852 NCBI chr  X:156,901,244...156,928,064
Ensembl chr  X:156,909,913...156,928,057
JBrowse link
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 decreases expression EXP triptolide results in decreased expression of LAMTOR1 protein CTD PMID:32519852 NCBI chr 1:166,991,474...166,997,045
Ensembl chr 1:166,991,474...166,997,045
JBrowse link
G Lcat lecithin cholesterol acyltransferase increases expression ISO triptolide results in increased expression of LCAT mRNA CTD PMID:32835833 NCBI chr19:37,913,333...37,916,799
Ensembl chr19:37,913,336...37,916,813
JBrowse link
G Ldb3 LIM domain binding 3 increases expression ISO triptolide results in increased expression of LDB3 mRNA CTD PMID:32835833 NCBI chr16:10,878,348...10,943,016
Ensembl chr16:10,878,334...10,941,501
JBrowse link
G Lepr leptin receptor decreases expression ISO triptolide results in decreased expression of LEPR mRNA CTD PMID:32835833 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G Letmd1 LETM1 domain containing 1 increases expression EXP triptolide results in increased expression of LETMD1 protein CTD PMID:32519852 NCBI chr 7:142,106,364...142,119,900
Ensembl chr 7:142,106,465...142,119,899
JBrowse link
G Lgi4 leucine-rich repeat LGI family, member 4 increases expression ISO triptolide results in increased expression of LGI4 mRNA CTD PMID:32835833 NCBI chr 1:89,491,588...89,502,939
Ensembl chr 1:89,491,654...89,502,974
JBrowse link
G Lipg lipase G, endothelial type decreases expression ISO triptolide results in decreased expression of LIPG mRNA CTD PMID:32835833 NCBI chr18:70,903,528...70,924,434
Ensembl chr18:70,901,710...70,924,708
JBrowse link
G Litaf lipopolysaccharide-induced TNF factor increases expression ISO triptolide results in increased expression of LITAF mRNA CTD PMID:32835833 NCBI chr10:4,753,546...4,763,272
Ensembl chr10:4,719,713...4,763,510
JBrowse link
G Lmna lamin A/C increases expression ISO triptolide results in increased expression of LMNA mRNA CTD PMID:32835833 NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516
JBrowse link
G LOC100909593 class II histocompatibility antigen, M alpha chain-like increases expression ISO triptolide results in increased expression of H2-DMA mRNA CTD PMID:32835833 NCBI chr20:3,935,501...3,938,915 JBrowse link
G LOC100912290 histone H4-like increases expression ISO triptolide results in increased expression of H4C4 mRNA CTD PMID:32835833 NCBI chr 4:170,092,457...170,117,607 JBrowse link
G LOC685081 similar to solute carrier family 22 (organic cation transporter), member 13 decreases expression EXP triptolide results in decreased expression of SLC22A13 protein CTD PMID:32519852 NCBI chr 8:127,905,478...127,914,897
Ensembl chr 8:127,909,147...127,912,860
JBrowse link
G Lonrf3 LON peptidase N-terminal domain and ring finger 3 increases expression ISO triptolide results in increased expression of LONRF3 mRNA CTD PMID:32835833 NCBI chr  X:122,937,987...122,973,289
Ensembl chr  X:122,938,009...122,973,321
JBrowse link
G Loxl4 lysyl oxidase-like 4 increases expression ISO triptolide results in increased expression of LOXL4 mRNA CTD PMID:32835833 NCBI chr 1:261,833,365...261,853,599
Ensembl chr 1:261,835,992...261,853,495
JBrowse link
G Lpin1 lipin 1 decreases expression ISO triptolide results in decreased expression of LPIN1 mRNA CTD PMID:32835833 NCBI chr 6:41,796,214...41,905,149
Ensembl chr 6:41,799,749...41,870,046
JBrowse link
G Lpxn leupaxin increases expression ISO triptolide results in increased expression of LPXN mRNA CTD PMID:32835833 NCBI chr 1:229,642,437...229,674,129
Ensembl chr 1:229,642,412...229,674,134
JBrowse link
G Lrrc14 leucine rich repeat containing 14 increases expression ISO triptolide results in increased expression of LRRC14 mRNA CTD PMID:32835833 NCBI chr 7:117,773,219...117,779,555
Ensembl chr 7:117,773,230...117,779,505
JBrowse link
G Lrrc51 leucine rich repeat containing 51 increases expression ISO triptolide results in increased expression of LRRC51 mRNA CTD PMID:32835833 NCBI chr 1:166,997,973...167,017,221
Ensembl chr 1:166,997,967...167,005,839
JBrowse link
G Lrrn4cl LRRN4 C-terminal like increases expression ISO triptolide results in increased expression of LRRN4CL mRNA CTD PMID:32835833 NCBI chr 1:225,046,248...225,050,963
Ensembl chr 1:225,048,149...225,051,696
JBrowse link
G Lrtm1 leucine-rich repeats and transmembrane domains 1 decreases expression ISO triptolide results in decreased expression of LRTM1 mRNA CTD PMID:32835833 NCBI chr16:4,993,728...5,005,110
Ensembl chr16:4,997,461...5,003,066
JBrowse link
G Lto1 LTO1 maturation factor of ABCE1 increases expression ISO triptolide results in increased expression of ORAOV1 mRNA CTD PMID:32835833 NCBI chr 1:218,075,995...218,082,700
Ensembl chr 1:218,076,116...218,080,824
JBrowse link
G Ly6e lymphocyte antigen 6 family member E increases expression EXP triptolide results in increased expression of LY6E protein CTD PMID:32519852 NCBI chr 7:116,355,426...116,359,862
Ensembl chr 7:116,355,698...116,359,862
JBrowse link
G Mab21l3 mab-21 like 3 increases expression ISO triptolide results in increased expression of MAB21L3 mRNA CTD PMID:32835833 NCBI chr 2:204,231,936...204,269,235
Ensembl chr 2:204,231,685...204,254,699
JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 increases expression EXP triptolide results in increased expression of MAD2L1 mRNA CTD PMID:23639586 NCBI chr 4:97,530,993...97,543,179
Ensembl chr 4:97,531,083...97,537,086
JBrowse link
G Mafb MAF bZIP transcription factor B decreases expression ISO triptolide results in decreased expression of MAFB mRNA CTD PMID:32835833 NCBI chr 3:156,338,993...156,340,913
Ensembl chr 3:156,339,004...156,340,913
JBrowse link
G Maff MAF bZIP transcription factor F affects expression ISO triptolide affects the expression of MAFF mRNA CTD PMID:32835833 NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
JBrowse link
G Map1s microtubule-associated protein 1S increases expression ISO triptolide results in increased expression of MAP1S mRNA CTD PMID:32835833 NCBI chr16:20,268,663...20,278,850
Ensembl chr16:20,267,581...20,278,814
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 decreases expression ISO triptolide results in decreased expression of MAP2K6 mRNA CTD PMID:32835833 NCBI chr10:98,707,160...98,823,054
Ensembl chr10:98,706,960...98,823,287
JBrowse link
G Map7d1 MAP7 domain containing 1 increases expression ISO triptolide results in increased expression of MAP7D1 mRNA CTD PMID:32835833 NCBI chr 5:144,250,416...144,274,981
Ensembl chr 5:144,250,419...144,274,981
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP triptolide inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] CTD PMID:21717513 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO triptolide inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of MAPK14 protein] CTD PMID:17507666 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP triptolide inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] CTD PMID:21717513 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 increases expression ISO triptolide results in increased expression of MAPK8IP3 mRNA CTD PMID:32835833 NCBI chr10:14,259,394...14,299,276
Ensembl chr10:14,260,787...14,299,167
JBrowse link
G Mast3 microtubule associated serine/threonine kinase 3 increases expression EXP triptolide results in increased expression of MAST3 protein CTD PMID:32519852 NCBI chr16:20,387,330...20,414,767
Ensembl chr16:20,395,845...20,414,767
JBrowse link
G Mbnl1 muscleblind-like splicing regulator 1 increases expression EXP triptolide results in increased expression of MBNL1 protein CTD PMID:32519852 NCBI chr 2:150,698,248...150,867,791
Ensembl chr 2:150,756,185...150,869,690
JBrowse link
G Mcee methylmalonyl CoA epimerase increases expression EXP triptolide results in increased expression of MCEE protein CTD PMID:32519852 NCBI chr 1:125,229,487...125,252,692
Ensembl chr 1:125,229,469...125,252,666
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member increases expression ISO triptolide results in increased expression of MCL1 protein CTD PMID:26990902 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression EXP triptolide results in increased expression of MCM6 mRNA CTD PMID:23639586 NCBI chr13:45,042,882...45,068,073
Ensembl chr13:45,042,882...45,068,077
JBrowse link
G Mcrip1 MAPK regulated co-repressor interacting protein 1 increases expression ISO triptolide results in increased expression of MCRIP1 mRNA CTD PMID:32835833 NCBI chr10:109,720,144...109,727,595
Ensembl chr10:109,720,144...109,722,195
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO triptolide results in increased expression of MDM2 mRNA CTD PMID:32835833 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Me1 malic enzyme 1 decreases expression ISO triptolide results in decreased expression of ME1 mRNA CTD PMID:32835833 NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
JBrowse link
G Med23 mediator complex subunit 23 increases expression EXP triptolide results in increased expression of MED23 protein CTD PMID:32519852 NCBI chr 1:21,539,765...21,587,675
Ensembl chr 1:21,539,765...21,586,910
JBrowse link
G Mep1a meprin A subunit alpha increases expression EXP triptolide results in increased expression of MEP1A protein CTD PMID:32519852 NCBI chr 9:20,048,163...20,077,678
Ensembl chr 9:20,048,121...20,077,702
JBrowse link
G Mep1b meprin A subunit beta increases expression EXP triptolide results in increased expression of MEP1B protein CTD PMID:32519852 NCBI chr18:15,063,159...15,090,877
Ensembl chr18:15,063,079...15,089,988
JBrowse link
G Mfn2 mitofusin 2 decreases expression
multiple interactions
ISO triptolide results in decreased expression of MFN2 protein
10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [triptolide results in decreased expression of MFN2 protein]
CTD PMID:30836114 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
G Mfsd2a major facilitator superfamily domain containing 2A decreases expression ISO triptolide results in decreased expression of MFSD2A mRNA CTD PMID:32835833 NCBI chr 5:140,642,865...140,657,759
Ensembl chr 5:140,642,885...140,657,745
JBrowse link
G Mfsd4b major facilitator superfamily domain containing 4B decreases expression ISO triptolide results in decreased expression of MFSD4B1 mRNA CTD PMID:32835833 NCBI chr20:44,996,864...45,005,155
Ensembl chr20:44,995,755...45,005,035
JBrowse link
G Mical2 microtubule associated monooxygenase, calponin and LIM domain containing 2 increases expression ISO triptolide results in increased expression of MICAL2 mRNA CTD PMID:32835833 NCBI chr 1:177,048,607...177,173,729
Ensembl chr 1:177,048,655...177,173,995
JBrowse link
G Mical3 microtubule associated monooxygenase, calponin and LIM domain containing 3 increases expression ISO triptolide results in increased expression of MICAL3 mRNA CTD PMID:32835833 NCBI chr 4:153,484,876...153,631,986
Ensembl chr 4:153,484,876...153,593,773
JBrowse link
G Mir141 microRNA 141 multiple interactions ISO [triptolide co-treated with tariquidar] results in increased activity of MIR141 protein CTD PMID:26134275 NCBI chr 4:157,236,346...157,236,439
Ensembl chr 4:157,236,346...157,236,439
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO triptolide results in decreased expression of MKI67 protein CTD PMID:24842335 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mlkl mixed lineage kinase domain like pseudokinase multiple interactions
increases expression
ISO [triptolide co-treated with Lipopolysaccharides] results in increased expression of MLKL protein; [triptolide co-treated with Lipopolysaccharides] results in increased expression of MLKL protein modified form; necrostatin-1 inhibits the reaction [[triptolide co-treated with Lipopolysaccharides] results in increased expression of MLKL protein modified form]; necrostatin-1 inhibits the reaction [[triptolide co-treated with Lipopolysaccharides] results in increased expression of MLKL protein]
triptolide results in increased expression of MLKL mRNA
CTD PMID:30633930 PMID:32835833 NCBI chr19:43,508,416...43,535,050
Ensembl chr19:43,506,976...43,528,851
JBrowse link
G Mmd2 monocyte to macrophage differentiation-associated 2 decreases expression ISO triptolide results in decreased expression of MMD2 mRNA CTD PMID:32835833 NCBI chr12:14,021,724...14,078,121
Ensembl chr12:14,021,727...14,078,134
JBrowse link
G Mme membrane metallo-endopeptidase increases expression
decreases expression
EXP
ISO
triptolide results in increased expression of MME protein
triptolide results in decreased expression of MME mRNA
CTD PMID:32519852 PMID:32835833 NCBI chr 2:153,799,203...153,880,910
Ensembl chr 2:153,803,349...153,880,738
JBrowse link
G Mmp12 matrix metallopeptidase 12 increases expression ISO triptolide results in increased expression of MMP12 mRNA CTD PMID:32835833 NCBI chr 8:5,594,717...5,616,494
Ensembl chr 8:5,606,592...5,616,493
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression ISO triptolide results in decreased expression of MMP2 mRNA; triptolide results in decreased expression of MMP2 protein CTD PMID:26420756 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression
multiple interactions
ISO triptolide results in decreased expression of MMP9 protein
triptolide inhibits the reaction [FSL-1 lipoprotein, synthetic results in increased expression of MMP9 mRNA]; triptolide inhibits the reaction [FSL-1 lipoprotein, synthetic results in increased secretion of MMP9 protein]
CTD PMID:25200491 PMID:26420756 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mogat2 monoacylglycerol O-acyltransferase 2 increases expression ISO triptolide results in increased expression of MOGAT2 mRNA CTD PMID:32835833 NCBI chr 1:164,181,762...164,205,222
Ensembl chr 1:164,181,764...164,205,222
JBrowse link
G Mov10 Mov10 RISC complex RNA helicase decreases expression ISO triptolide results in decreased expression of MOV10 mRNA CTD PMID:32835833 NCBI chr 2:207,277,088...207,301,245
Ensembl chr 2:207,278,161...207,300,854
JBrowse link
G Mpc1 mitochondrial pyruvate carrier 1 decreases expression EXP triptolide results in decreased expression of MPC1 protein CTD PMID:32519852 NCBI chr 1:53,026,608...53,038,229
Ensembl chr 1:53,026,608...53,038,229
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO triptolide promotes the reaction [Lipopolysaccharides results in increased expression of MPO mRNA] CTD PMID:30633930 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mpp7 membrane palmitoylated protein 7 increases expression ISO triptolide results in increased expression of MPP7 mRNA CTD PMID:32835833 NCBI chr17:60,057,077...60,250,303
Ensembl chr17:60,059,949...60,250,352
JBrowse link
G Mreg melanoregulin increases expression ISO triptolide results in increased expression of MREG mRNA CTD PMID:32835833 NCBI chr 9:79,490,058...79,559,768
Ensembl chr 9:79,490,050...79,545,024
JBrowse link
G Mrps5 mitochondrial ribosomal protein S5 increases expression EXP triptolide results in increased expression of MRPS5 protein CTD PMID:32519852 NCBI chr 3:120,165,953...120,182,536
Ensembl chr 3:120,165,913...120,182,536
JBrowse link
G Msmo1 methylsterol monooxygenase 1 decreases expression ISO triptolide results in decreased expression of MSMO1 mRNA CTD PMID:32835833 NCBI chr16:26,859,441...26,875,880
Ensembl chr16:26,859,397...26,875,973
JBrowse link
G Mt-nd1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 increases expression EXP triptolide results in increased expression of ND1 protein CTD PMID:32519852 NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694
JBrowse link
G Mt1 metallothionein 1 decreases expression
increases expression
EXP triptolide results in decreased expression of MT1 protein
triptolide results in increased expression of MT1M protein
CTD PMID:32519852 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mtdh metadherin increases expression ISO triptolide results in increased expression of MTDH mRNA CTD PMID:32835833 NCBI chr 7:72,771,018...72,830,599
Ensembl chr 7:72,772,440...72,827,908
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO triptolide results in increased expression of and results in increased phosphorylation of MTOR protein CTD PMID:26990902 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Mug1 murinoglobulin 1 increases expression EXP triptolide results in increased expression of MUG1 protein CTD PMID:32519852 NCBI chr 4:154,676,382...154,729,288
Ensembl chr 4:154,391,647...154,729,310
JBrowse link
G Mug2 murinoglobulin 2 decreases expression ISO triptolide results in decreased expression of MUG2 mRNA CTD PMID:32835833 NCBI chr 4:154,215,262...154,282,608
Ensembl chr 4:154,215,250...154,282,608
JBrowse link
G Mvd mevalonate diphosphate decarboxylase increases expression
decreases expression
EXP
ISO
triptolide results in increased expression of MVD protein
triptolide results in decreased expression of MVD mRNA
CTD PMID:32519852 PMID:32835833 NCBI chr19:55,258,910...55,268,933
Ensembl chr19:55,258,905...55,268,951
JBrowse link
G Mx1 MX dynamin like GTPase 1 increases expression EXP triptolide results in increased expression of MX1 protein CTD PMID:32519852 NCBI chr11:37,891,150...37,916,775
Ensembl chr11:37,891,156...37,914,983
JBrowse link
G Mybl1 MYB proto-oncogene like 1 increases expression ISO triptolide results in increased expression of MYBL1 mRNA CTD PMID:32835833 NCBI chr 5:9,279,756...9,315,112
Ensembl chr 5:9,279,970...9,315,114
JBrowse link
G Mybl2 MYB proto-oncogene like 2 increases expression ISO triptolide results in increased expression of MYBL2 mRNA CTD PMID:32835833 NCBI chr 3:159,421,638...159,450,087
Ensembl chr 3:159,421,671...159,450,086
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression
increases expression
EXP
ISO
triptolide results in decreased expression of MYC mRNA
triptolide results in increased expression of MYC mRNA
triptolide results in decreased expression of MYC protein
CTD PMID:12533674 PMID:23639586 PMID:32835833 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Mycbpap Mycbp associated protein increases expression ISO triptolide results in increased expression of MYCBPAP mRNA CTD PMID:32835833 NCBI chr10:82,232,105...82,253,649
Ensembl chr10:82,232,107...82,252,963
JBrowse link
G Mycl MYCL proto-oncogene, bHLH transcription factor decreases expression ISO triptolide results in decreased expression of MYCL mRNA CTD PMID:32835833 NCBI chr 5:140,691,947...140,698,837
Ensembl chr 5:140,692,779...140,698,609
JBrowse link
G Myh1 myosin heavy chain 1 decreases expression ISO triptolide results in decreased expression of MYH1 mRNA CTD PMID:32061799 NCBI chr10:53,740,841...53,764,610
Ensembl chr10:53,713,938...53,848,347
JBrowse link
G Myh2 myosin heavy chain 2 decreases expression ISO triptolide results in decreased expression of MYH2 mRNA CTD PMID:32061799 NCBI chr10:53,711,895...53,738,164
Ensembl chr10:53,713,938...53,848,347
JBrowse link
G Myh4 myosin heavy chain 4 decreases expression ISO triptolide results in decreased expression of MYH4 mRNA CTD PMID:32061799 NCBI chr10:53,778,456...53,801,605
Ensembl chr10:53,713,938...53,848,347
JBrowse link
G Myh7 myosin heavy chain 7 decreases expression ISO triptolide results in decreased expression of MYH7 mRNA CTD PMID:32061799 NCBI chr15:33,605,769...33,657,761
Ensembl chr15:33,634,422...33,656,089
JBrowse link
G Myh7b myosin heavy chain 7B increases expression ISO triptolide results in increased expression of MYH7B mRNA CTD PMID:32835833 NCBI chr 3:151,105,038...151,150,621
Ensembl chr 3:151,126,591...151,150,344
JBrowse link
G Myl9 myosin light chain 9 decreases expression EXP triptolide results in decreased expression of MYL9 protein CTD PMID:32519852 NCBI chr 3:152,857,573...152,863,961
Ensembl chr 3:152,857,592...152,863,960
JBrowse link
G Myo19 myosin XIX increases expression ISO triptolide results in increased expression of MYO19 mRNA CTD PMID:32835833 NCBI chr10:72,198,475...72,227,892
Ensembl chr10:72,197,977...72,227,462
JBrowse link
G Myo5c myosin VC increases expression EXP triptolide results in increased expression of MYO5C protein CTD PMID:32519852 NCBI chr 8:82,171,296...82,248,109
Ensembl chr 8:82,171,497...82,247,544
JBrowse link
G Myom1 myomesin 1 increases expression ISO triptolide results in increased expression of MYOM1 mRNA CTD PMID:32835833 NCBI chr 9:119,353,840...119,469,196
Ensembl chr 9:119,353,840...119,468,715
JBrowse link
G Myrfl myelin regulatory factor-like increases expression ISO triptolide results in increased expression of MYRFL mRNA CTD PMID:32835833 NCBI chr 7:59,799,181...59,916,758
Ensembl chr 7:59,799,419...59,882,077
JBrowse link
G Naaladl2 N-acetylated alpha-linked acidic dipeptidase-like 2 decreases expression ISO triptolide results in decreased expression of NAALADL2 mRNA CTD PMID:32835833 NCBI chr 2:109,092,931...110,424,885 JBrowse link
G Nampt nicotinamide phosphoribosyltransferase decreases expression ISO triptolide results in decreased expression of NAMPT mRNA CTD PMID:29723566 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
JBrowse link
G Nat8f4 N-acetyltransferase 8 (GCN5-related) family member 4 increases expression ISO triptolide results in increased expression of NAT8F4 mRNA CTD PMID:32835833 NCBI chr 4:117,755,646...117,760,096
Ensembl chr 4:117,757,455...117,758,135
Ensembl chr 4:117,757,455...117,758,135
JBrowse link
G Nat8f5 N-acetyltransferase 8 (GCN5-related) family member 5 affects expression ISO triptolide affects the expression of NAT8F5 mRNA CTD PMID:32835833 NCBI chr 4:117,506,731...117,531,480
Ensembl chr 4:117,506,732...117,531,480
JBrowse link
G Nbeal2 neurobeachin-like 2 increases expression ISO triptolide results in increased expression of NBEAL2 mRNA CTD PMID:32835833 NCBI chr 8:118,893,987...118,924,390
Ensembl chr 8:118,893,995...118,926,613
JBrowse link
G Ncbp1 nuclear cap binding protein subunit 1 increases expression ISO triptolide results in increased expression of NCBP1 mRNA CTD PMID:32835833 NCBI chr 5:61,734,118...61,767,098
Ensembl chr 5:61,734,118...61,766,481