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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:imidazole
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Accession:CHEBI:14434 term browser browse the term
Synonyms:related_synonym: Formula=C3H4N2
 xref: Wikipedia:Imidazole



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1H-imidazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 multiple interactions ISO imidazole promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein] CTD PMID:17196553 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Cat catalase decreases activity ISO imidazole analog results in decreased activity of CAT protein CTD PMID:23696008 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP imidazole results in increased expression of CYP2E1 protein CTD PMID:3337723 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 decreases activity ISO imidazole results in decreased activity of ENPP7 protein CTD PMID:12885774 NCBI chr10:104,242,223...104,246,589
Ensembl chr10:104,242,223...104,246,589
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression EXP imidazole results in increased expression of GSTA2 mRNA CTD PMID:8951341 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression EXP imidazole results in increased expression of GSTA3 mRNA CTD PMID:8951341 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression EXP imidazole results in increased expression of GSTA5 mRNA CTD PMID:8951341 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP imidazole results in increased expression of GSTM1 mRNA CTD PMID:8951341 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO imidazole results in increased expression of and results in increased secretion of IL1B protein CTD PMID:29953848 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 increases expression ISO imidazole results in increased expression of IL6 protein CTD PMID:29953848 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Sdr16c5 short chain dehydrogenase/reductase family 16C, member 5 decreases activity ISO imidazole results in decreased activity of SDR16C5 protein CTD PMID:18926804 NCBI chr 5:17,018,813...17,043,974
Ensembl chr 5:17,018,813...17,040,970
JBrowse link
G Tyr tyrosinase multiple interactions
increases expression
ISO Estradiol inhibits the reaction [imidazole results in increased expression of TYR protein]; Estriol inhibits the reaction [imidazole results in increased expression of TYR protein] CTD PMID:3127403 NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20056
    chemical entity 20055
      molecular entity 20054
        mancude ring 8576
          organic mancude parent 8576
            mancude organic heterocyclic parent 8576
              mancude organic heteromonocyclic parent 5104
                imidazole 12
                  1H-imidazole + 12
                  4H-imidazole 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20056
    subatomic particle 20054
      composite particle 20054
        hadron 20054
          baryon 20054
            nucleon 20054
              atomic nucleus 20054
                atom 20054
                  main group element atom 19956
                    p-block element atom 19956
                      carbon group element atom 19882
                        carbon atom 19875
                          organic molecular entity 19875
                            organic molecule 19822
                              organic cyclic compound 19575
                                organic heterocyclic compound 18798
                                  heteroarene 16604
                                    monocyclic heteroarene 13603
                                      azole 12834
                                        diazole 8623
                                          imidazoles 7717
                                            imidazole 12
                                              1H-imidazole + 12
                                              4H-imidazole 0
paths to the root