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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:imidazole
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Accession:CHEBI:14434 term browser browse the term
Synonyms:related_synonym: Formula=C3H4N2
 xref: Wikipedia:Imidazole



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1H-imidazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 multiple interactions ISO imidazole promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein] CTD PMID:17196553 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Cat catalase decreases activity ISO imidazole analog results in decreased activity of CAT protein CTD PMID:23696008 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP imidazole results in increased expression of CYP2E1 protein CTD PMID:3337723 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 decreases activity ISO imidazole results in decreased activity of ENPP7 protein CTD PMID:12885774 NCBI chr10:104,242,223...104,246,589
Ensembl chr10:104,242,223...104,246,589
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 increases expression EXP imidazole results in increased expression of GSTA3 mRNA CTD PMID:8951341 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression EXP imidazole results in increased expression of GSTA2 mRNA CTD PMID:8951341 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression EXP imidazole results in increased expression of GSTA5 mRNA CTD PMID:8951341 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP imidazole results in increased expression of GSTM1 mRNA CTD PMID:8951341 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO imidazole results in increased expression of and results in increased secretion of IL1B protein CTD PMID:29953848 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 increases expression ISO imidazole results in increased expression of IL6 protein CTD PMID:29953848 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Sdr16c5 short chain dehydrogenase/reductase family 16C, member 5 decreases activity ISO imidazole results in decreased activity of SDR16C5 protein CTD PMID:18926804 NCBI chr 5:17,018,813...17,043,974
Ensembl chr 5:17,018,813...17,040,970
JBrowse link
G Tyr tyrosinase multiple interactions
increases expression
ISO Estradiol inhibits the reaction [imidazole results in increased expression of TYR protein]; Estriol inhibits the reaction [imidazole results in increased expression of TYR protein] CTD PMID:3127403 NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19823
    chemical entity 19823
      molecular entity 19821
        mancude ring 8362
          organic mancude parent 8362
            mancude organic heterocyclic parent 8362
              mancude organic heteromonocyclic parent 4798
                imidazole 12
                  1H-imidazole + 12
                  4H-imidazole 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19823
    subatomic particle 19821
      composite particle 19821
        hadron 19821
          baryon 19821
            nucleon 19821
              atomic nucleus 19821
                atom 19821
                  main group element atom 19720
                    p-block element atom 19720
                      carbon group element atom 19643
                        carbon atom 19633
                          organic molecular entity 19633
                            organic molecule 19572
                              organic cyclic compound 19366
                                organic heterocyclic compound 18604
                                  heteroarene 16534
                                    monocyclic heteroarene 13441
                                      azole 12634
                                        diazole 8398
                                          imidazoles 7693
                                            imidazole 12
                                              1H-imidazole + 12
                                              4H-imidazole 0
paths to the root