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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:(R)-lisofylline
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Accession:CHEBI:143527 term browser browse the term
Definition:A 1-(5-hydroxyhexyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione that has (R)-configuration. A synthetic small molecule which was under development for the treatment of type 1 diabetes mellitus.
Synonyms:exact_synonym: 1-[(5R)-5-hydroxyhexyl]-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione
 related_synonym: (R)-1-(5-hydroxyhexyl)-3,7-dimethylxanthine;   (R)-LSF;   1-(5R-hydroxyhexyl)-3,7-dimethylxanthine;   1-[(5R)-5-hydroxyhexyl]-3,7-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione;   1-[(R)-5-hydroxyhexyl]theobromine;   CT-1501R;   Formula=C13H20N4O3;   InChI=1S/C13H20N4O3/c1-9(18)6-4-5-7-17-12(19)10-11(14-8-15(10)2)16(3)13(17)20/h8-9,18H,4-7H2,1-3H3/t9-/m1/s1;   InChIKey=NSMXQKNUPPXBRG-SECBINFHSA-N;   ProTec;   SMILES=C=12N(C=NC1N(C(N(C2=O)CCCC[C@H](O)C)=O)C)C;   lisofilina;   lisofylline;   lisofyllinum;   lisophylline
 xref: CAS:100324-81-0;   DrugBank:DB12406;   KEGG:D04748;   PMID:10330034;   PMID:11902249;   PMID:12242464;   PMID:12717280;   PMID:15588708;   PMID:25663650;   PMID:28730281;   PMID:30300750;   PMID:7735959;   Patent:WO2009099582;   Wikipedia:Lisofylline
 cyclic_relationship: is_enantiomer_of CHEBI:143564



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Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    role 19759
      biological role 19759
        immunomodulator 14905
          (R)-lisofylline 0
            rac-lisofylline 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19809
      composite particle 19809
        hadron 19809
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19706
                    p-block element atom 19706
                      carbon group element atom 19628
                        carbon atom 19618
                          organic molecular entity 19618
                            organic molecule 19558
                              organic cyclic compound 19349
                                organic heterocyclic compound 18582
                                  organic heteropolycyclic compound 18059
                                    organic heterobicyclic compound 16869
                                      imidazopyrimidine 5614
                                        purines 5612
                                          aminopurine 4429
                                            2-aminopurines 4035
                                              guanine 3999
                                                xanthine 3909
                                                  methylxanthine 1145
                                                    dimethylxanthine 540
                                                      1-(5-hydroxyhexyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione 0
                                                        (R)-lisofylline 0
                                                          rac-lisofylline 0
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