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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:glycerol 1-phosphate
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Accession:CHEBI:14336 term browser browse the term
Definition:A glycerol monophosphate having the phosphate group located at position 1.
Synonyms:related_synonym: 1,2,3-propanetriol, 1-(dihydrogen phosphate);   1-(Dihydrogen phosphate) Glycerol;   1-glycerophosphate;   1-glycerophosphoric acid;   1-phosphoglycerol;   2,3-dihydroxypropyl dihydrogen phosphate;   2,3-hydroxy-1-propyl dihydrogen phosphate;   3-glycerophosphate;   D,L-alpha-glycerol-phosphate;   DL-Glycerol 3-phosphate;   DL-Glyceryl 1-phosphate;   DL-glycerol 1-phosphate;   Formula=C3H9O6P;   InChI=1S/C3H9O6P/c4-1-3(5)2-9-10(6,7)8/h3-5H,1-2H2,(H2,6,7,8);   InChIKey=AWUCVROLDVIAJX-UHFFFAOYSA-N;   PG;   SMILES=OCC(O)COP(O)(O)=O;   alpha-glycerophosphoric acid;   alpha-phosphoglycerol;   glycerol alpha-phosphate;   rac-Glycerol 1-phosphate
 xref: CAS:57-03-4;   HMDB:HMDB0000126;   KEGG:C03189
 xref_mesh: MESH:C029620
 xref: MetaCyc:Glycerol-1-phosphate;   PMID:1694860;   PMID:22770225;   PMID:29438107;   PMID:6083437;   Reaxys:1723974;   Wikipedia:Glycerol_1-phosphate
 cyclic_relationship: is_conjugate_acid_of CHEBI:231935



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glycerol 1-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gk glycerol kinase multiple interactions ISO 1-butyrylglycerol promotes the reaction [[GK protein results in increased metabolism of Glycerol] which results in increased chemical synthesis of alpha-glycerophosphoric acid]; [GK protein results in increased metabolism of Glycerol] which results in increased chemical synthesis of alpha-glycerophosphoric acid; monoacetin promotes the reaction [[GK protein results in increased metabolism of Glycerol] which results in increased chemical synthesis of alpha-glycerophosphoric acid] CTD PMID:9606984 NCBI chr  X:84,745,543...84,820,425
Ensembl chr  X:84,745,543...84,820,425
JBrowse link
G Gpd2 glycerol phosphate dehydrogenase 2, mitochondrial multiple interactions EXP GPD2 protein inhibits the reaction [Dihydroxyacetone results in increased abundance of alpha-glycerophosphoric acid]; GPD2 protein inhibits the reaction [Glucose results in increased abundance of alpha-glycerophosphoric acid]; GPD2 protein inhibits the reaction [Glycerol results in increased abundance of alpha-glycerophosphoric acid] CTD PMID:31974165 NCBI chr 2:57,127,690...57,260,731
Ensembl chr 2:57,127,647...57,260,731
JBrowse link
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial multiple interactions
increases abundance
EXP Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of alpha-glycerophosphoric acid] CTD PMID:27469509 NCBI chr 7:79,744,594...79,768,356
Ensembl chr 7:79,744,594...79,765,140
JBrowse link
G Runx2 runt related transcription factor 2 multiple interactions ISO [SAG compound co-treated with 2,4-di-tert-butylphenol co-treated with Fibroblast Growth Factor 2 co-treated with Ascorbic Acid co-treated with alpha-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of RUNX2 mRNA CTD PMID:36682590 NCBI chr17:44,806,873...45,125,518
Ensembl chr17:44,806,874...45,125,684
JBrowse link
G Sp7 Sp7 transcription factor 7 multiple interactions ISO [SAG compound co-treated with 2,4-di-tert-butylphenol co-treated with Fibroblast Growth Factor 2 co-treated with Ascorbic Acid co-treated with alpha-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of SP7 mRNA CTD PMID:36682590 NCBI chr15:102,265,038...102,275,498
Ensembl chr15:102,265,041...102,275,617
JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions ISO [SAG compound co-treated with 2,4-di-tert-butylphenol co-treated with Fibroblast Growth Factor 2 co-treated with Ascorbic Acid co-treated with alpha-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA CTD PMID:36682590 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22188
    role 22173
      biological role 22172
        osmolyte 3437
          glycerol 3157
            glycerol phosphate 146
              glycerol monophosphate 86
                glycerol 1-phosphate 6
                  sn-glycerol 1-phosphate 0
                  sn-glycerol 3-phosphate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 22188
    subatomic particle 22180
      composite particle 22180
        hadron 22180
          baryon 22180
            nucleon 22180
              atomic nucleus 22180
                atom 22180
                  main group element atom 22114
                    p-block element atom 22114
                      chalcogen 21436
                        oxygen atom 21414
                          oxygen molecular entity 21414
                            hydroxides 20789
                              oxoacid 20084
                                pnictogen oxoacid 13640
                                  phosphorus oxoacid 12732
                                    phosphoric acids 11713
                                      phosphoric acid 11713
                                        phosphoric acid derivative 11515
                                          phosphate 11514
                                            organic phosphate 11514
                                              carbohydrate phosphate 1857
                                                alditol phosphate 146
                                                  glycerol phosphate 146
                                                    glycerol monophosphate 86
                                                      glycerol 1-phosphate 6
                                                        sn-glycerol 1-phosphate 0
                                                        sn-glycerol 3-phosphate 0
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