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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:glycerol 1-phosphate
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Accession:CHEBI:14336 term browser browse the term
Definition:A glycerol monophosphate having the phosphate group located at position 1.
Synonyms:related_synonym: 1,2,3-propanetriol, 1-(dihydrogen phosphate);   1-(Dihydrogen phosphate) Glycerol;   1-glycerophosphate;   1-glycerophosphoric acid;   1-phosphoglycerol;   2,3-dihydroxypropyl dihydrogen phosphate;   2,3-hydroxy-1-propyl dihydrogen phosphate;   3-glycerophosphate;   D,L-alpha-glycerol-phosphate;   DL-Glycerol 3-phosphate;   DL-Glyceryl 1-phosphate;   DL-glycerol 1-phosphate;   Formula=C3H9O6P;   InChI=1S/C3H9O6P/c4-1-3(5)2-9-10(6,7)8/h3-5H,1-2H2,(H2,6,7,8);   InChIKey=AWUCVROLDVIAJX-UHFFFAOYSA-N;   PG;   SMILES=OCC(O)COP(O)(O)=O;   alpha-glycerophosphoric acid;   alpha-phosphoglycerol;   glycerol alpha-phosphate;   rac-Glycerol 1-phosphate
 xref: CAS:57-03-4;   HMDB:HMDB0000126;   KEGG:C03189
 xref_mesh: MESH:C029620
 xref: MetaCyc:Glycerol-1-phosphate;   PMID:1694860;   PMID:22770225;   PMID:29438107;   PMID:6083437;   Reaxys:1723974;   Wikipedia:Glycerol_1-phosphate
 cyclic_relationship: is_conjugate_acid_of CHEBI:231935



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glycerol 1-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein multiple interactions
decreases abundance
ISO PF-06840003 inhibits the reaction [APP protein mutant form results in decreased abundance of alpha-glycerophosphoric acid]
[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of alpha-glycerophosphoric acid; IDO1 protein affects the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of alpha-glycerophosphoric acid]; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of alpha-glycerophosphoric acid]
CTD PMID:39172838 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Gk glycerol kinase multiple interactions EXP 1-butyrylglycerol promotes the reaction [[GK protein results in increased metabolism of Glycerol] which results in increased chemical synthesis of alpha-glycerophosphoric acid]; [GK protein results in increased metabolism of Glycerol] which results in increased chemical synthesis of alpha-glycerophosphoric acid; monoacetin promotes the reaction [[GK protein results in increased metabolism of Glycerol] which results in increased chemical synthesis of alpha-glycerophosphoric acid] CTD PMID:9606984 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:50,163,123...50,238,631
JBrowse link
G Gpd2 glycerol-3-phosphate dehydrogenase 2 multiple interactions ISO GPD2 protein inhibits the reaction [Dihydroxyacetone results in increased abundance of alpha-glycerophosphoric acid]; GPD2 protein inhibits the reaction [Glucose results in increased abundance of alpha-glycerophosphoric acid]; GPD2 protein inhibits the reaction [Glycerol results in increased abundance of alpha-glycerophosphoric acid] CTD PMID:31974165 NCBI chr 3:41,800,552...41,937,729
Ensembl chr 3:41,801,930...41,936,901
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
increases abundance
ISO Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of alpha-glycerophosphoric acid] CTD PMID:27469509 NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 multiple interactions ISO IDO1 protein affects the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of alpha-glycerophosphoric acid] CTD PMID:39172838 NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730
JBrowse link
G Mapt microtubule-associated protein tau decreases abundance
multiple interactions
ISO MAPT protein mutant form results in decreased abundance of alpha-glycerophosphoric acid
PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of alpha-glycerophosphoric acid]
CTD PMID:39172838 NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Psen1 presenilin 1 multiple interactions ISO [APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of alpha-glycerophosphoric acid; IDO1 protein affects the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of alpha-glycerophosphoric acid]; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of alpha-glycerophosphoric acid] CTD PMID:39172838 NCBI chr 6:109,054,160...109,106,191
Ensembl chr 6:103,323,120...103,371,650
JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions ISO [SAG compound co-treated with 2,4-di-tert-butylphenol co-treated with Fibroblast Growth Factor 2 co-treated with Ascorbic Acid co-treated with alpha-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of RUNX2 mRNA CTD PMID:36682590 NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G Sp7 Sp7 transcription factor multiple interactions ISO [SAG compound co-treated with 2,4-di-tert-butylphenol co-treated with Fibroblast Growth Factor 2 co-treated with Ascorbic Acid co-treated with alpha-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of SP7 mRNA CTD PMID:36682590 NCBI chr 7:135,363,193...135,373,376
Ensembl chr 7:133,484,609...133,494,847
JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions ISO [SAG compound co-treated with 2,4-di-tert-butylphenol co-treated with Fibroblast Growth Factor 2 co-treated with Ascorbic Acid co-treated with alpha-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA CTD PMID:36682590 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,308,885...5,315,162
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20856
    role 20816
      biological role 20814
        osmolyte 3482
          glycerol 3210
            glycerol phosphate 160
              glycerol monophosphate 93
                glycerol 1-phosphate 10
                  sn-glycerol 1-phosphate 0
                  sn-glycerol 3-phosphate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20856
    subatomic particle 20854
      composite particle 20854
        hadron 20854
          baryon 20854
            nucleon 20854
              atomic nucleus 20854
                atom 20854
                  main group element atom 20777
                    p-block element atom 20777
                      chalcogen 20489
                        oxygen atom 20455
                          oxygen molecular entity 20455
                            hydroxides 20228
                              oxoacid 19285
                                pnictogen oxoacid 15114
                                  phosphorus oxoacid 14668
                                    phosphoric acids 13988
                                      phosphoric acid 13988
                                        phosphoric acid derivative 13899
                                          phosphate 13898
                                            organic phosphate 13898
                                              carbohydrate phosphate 1976
                                                alditol phosphate 160
                                                  glycerol phosphate 160
                                                    glycerol monophosphate 93
                                                      glycerol 1-phosphate 10
                                                        sn-glycerol 1-phosphate 0
                                                        sn-glycerol 3-phosphate 0
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