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ONTOLOGY REPORT - ANNOTATIONS


Term:2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid
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Accession:CHEBI:143205 term browser browse the term
Definition:A perfluorinated compound that is 2-propoxypentanoic acid in which all 11 of the hydrogens attached to carbon atoms have been replaced by fluorine atoms. Used as an alternative to perfluorooctanoic acid in the fluoropolymer industry for years, its widespread environmental distribution, high bioaccumulation capability, and human exposure have caused great concern, particularly as its potential toxicity and health risk is still largely unknown.
Synonyms:related_synonym: 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propionic acid;   FRD-908;   Formula=C6HF11O3;   GenX;   HFPO-DA;   InChI=1S/C6HF11O3/c7-2(1(18)19,4(10,11)12)20-6(16,17)3(8,9)5(13,14)15/h(H,18,19);   InChIKey=CSEBNABAWMZWIF-UHFFFAOYSA-N;   SMILES=C(C(C(OC(C(O)=O)(F)C(F)(F)F)(F)F)(F)F)(F)(F)F;   hexafluoropropylene oxide dimer acid
 xref: CAS:13252-13-6 "ChemIDplus"
 xref_mesh: MESH:C000608800
 xref: PMID:20823541 "Europe PMC";   PMID:26106903 "Europe PMC";   PMID:28853567 "Europe PMC";   PMID:30207460 "Europe PMC";   PMID:30256633 "Europe PMC";   PMID:30594801 "Europe PMC";   PMID:30785727 "Europe PMC";   PMID:30920876 "Europe PMC";   PMID:31146223 "Europe PMC";   PMID:31181522 "Europe PMC";   PMID:31215065 "Europe PMC";   PMID:31251593 "Europe PMC";   Wikipedia:FRD-903


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2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acaa2 acetyl-CoA acyltransferase 2 JBrowse link 18 70,733,872 70,762,395 RGD:6480464
G Acadl acyl-CoA dehydrogenase, long chain JBrowse link 9 73,833,368 73,871,857 RGD:6480464
G Acadm acyl-CoA dehydrogenase medium chain JBrowse link 2 260,124,418 260,148,589 RGD:6480464
G Acox1 acyl-CoA oxidase 1 JBrowse link 10 104,724,534 104,748,003 RGD:6480464
G Acsl1 acyl-CoA synthetase long-chain family member 1 JBrowse link 16 48,937,456 49,003,898 RGD:6480464
G Acsl3 acyl-CoA synthetase long-chain family member 3 JBrowse link 9 84,569,601 84,593,565 RGD:6480464
G Acsl4 acyl-CoA synthetase long-chain family member 4 JBrowse link X 113,596,247 113,660,024 RGD:6480464
G Angptl4 angiopoietin-like 4 JBrowse link 7 18,627,814 18,634,043 RGD:6480464
G Aqp7 aquaporin 7 JBrowse link 5 57,358,297 57,372,332 RGD:6480464
G Cpt1a carnitine palmitoyltransferase 1A JBrowse link 1 218,568,157 218,629,679 RGD:6480464
G Cpt1b carnitine palmitoyltransferase 1B JBrowse link 7 130,395,211 130,404,731 RGD:6480464
G Cpt2 carnitine palmitoyltransferase 2 JBrowse link 5 127,505,646 127,523,016 RGD:6480464
G Dgat1 diacylglycerol O-acyltransferase 1 JBrowse link 7 117,566,363 117,576,735 RGD:6480464
G Ech1 enoyl-CoA hydratase 1 JBrowse link 1 87,009,798 87,015,996 RGD:6480464
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase JBrowse link 11 82,945,104 82,978,364 RGD:6480464
G Etfdh electron transfer flavoprotein dehydrogenase JBrowse link 2 178,367,547 178,389,641 RGD:6480464
G Fabp1 fatty acid binding protein 1 JBrowse link 4 99,063,181 99,066,957 RGD:6480464
G Fabp5 fatty acid binding protein 5 JBrowse link 2 93,981,662 93,985,322 RGD:6480464
G Fads2 fatty acid desaturase 2 JBrowse link 1 225,906,582 226,152,568 RGD:6480464
G Gk glycerol kinase JBrowse link X 54,227,291 54,303,897 RGD:6480464
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 JBrowse link 2 200,452,623 200,480,785 RGD:6480464
G Hspd1 heat shock protein family D (Hsp60) member 1 JBrowse link 9 61,680,529 61,691,202 RGD:6480464
G Lpl lipoprotein lipase JBrowse link 16 22,537,687 22,561,487 RGD:6480464
G Mlycd malonyl-CoA decarboxylase JBrowse link 19 52,032,950 52,048,773 RGD:6480464
G Pck1 phosphoenolpyruvate carboxykinase 1 JBrowse link 3 171,213,936 171,219,885 RGD:6480464
G Rxrg retinoid X receptor gamma JBrowse link 13 85,818,473 85,868,555 RGD:6480464
G Scd stearoyl-CoA desaturase JBrowse link 1 264,159,966 264,173,061 RGD:6480464
G Slc22a5 solute carrier family 22 member 5 JBrowse link 10 39,201,101 39,228,090 RGD:6480464
G Slc27a2 solute carrier family 27 member 2 JBrowse link 3 119,014,620 119,052,531 RGD:6480464
G Txnip thioredoxin interacting protein JBrowse link 2 198,683,168 198,686,971 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19657
    chemical entity 19655
      atom 19653
        nonmetal atom 19521
          oxygen atom 19179
            oxygen molecular entity 19179
              organooxygen compound 18625
                ether 15756
                  2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid 30
Path 2
Term Annotations click to browse term
  CHEBI ontology 19657
    subatomic particle 19653
      composite particle 19653
        hadron 19653
          baryon 19653
            nucleon 19653
              atomic nucleus 19653
                atom 19653
                  main group element atom 19534
                    p-block element atom 19534
                      carbon group element atom 19417
                        carbon atom 19409
                          organic molecular entity 19409
                            organic group 18338
                              organic divalent group 18329
                                organodiyl group 18329
                                  carbonyl group 18218
                                    carbonyl compound 18218
                                      carboxylic acid 17918
                                        monocarboxylic acid 17254
                                          2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid 30
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.