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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid
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Accession:CHEBI:143205 term browser browse the term
Definition:A perfluorinated compound that is 2-propoxypentanoic acid in which all 11 of the hydrogens attached to carbon atoms have been replaced by fluorine atoms. Used as an alternative to perfluorooctanoic acid in the fluoropolymer industry for years, its widespread environmental distribution, high bioaccumulation capability, and human exposure have caused great concern, particularly as its potential toxicity and health risk is still largely unknown.
Synonyms:related_synonym: 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propionic acid;   FRD-908;   Formula=C6HF11O3;   GenX;   HFPO-DA;   InChI=1S/C6HF11O3/c7-2(1(18)19,4(10,11)12)20-6(16,17)3(8,9)5(13,14)15/h(H,18,19);   InChIKey=CSEBNABAWMZWIF-UHFFFAOYSA-N;   SMILES=C(C(C(OC(C(O)=O)(F)C(F)(F)F)(F)F)(F)F)(F)(F)F;   hexafluoropropylene oxide dimer acid
 xref: CAS:13252-13-6
 xref_mesh: MESH:C000608800
 xref: PMID:20823541;   PMID:26106903;   PMID:28853567;   PMID:30207460;   PMID:30256633;   PMID:30594801;   PMID:30785727;   PMID:30920876;   PMID:31146223;   PMID:31181522;   PMID:31215065;   PMID:31251593;   Wikipedia:FRD-903



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2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid inhibits the reaction [ABCB1 protein results in increased transport of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]; 2-chloro-5-nitrobenzanilide inhibits the reaction [2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid inhibits the reaction [ABCB1 protein results in increased transport of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]] CTD PMID:32212926 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of ABCC1 mRNA CTD PMID:32790152 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of ABCC5 mRNA CTD PMID:32790152 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid inhibits the reaction [ABCG2 protein results in increased transport of BODIPY-FL prazosin] CTD PMID:32212926 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 increases expression EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of ACAA2 mRNA CTD PMID:30920876 PMID:33983380 NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249
JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain increases expression EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of ACADL mRNA CTD PMID:30920876 PMID:33983380 NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain increases expression EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of ACADM mRNA CTD PMID:30920876 PMID:33983380 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
JBrowse link
G Acox1 acyl-CoA oxidase 1 increases expression
decreases expression
EXP
ISO
2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of ACOX1 mRNA
2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of ACOX1 mRNA
CTD PMID:30920876 PMID:32790152 PMID:33983380 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Acox2 acyl-CoA oxidase 2 increases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of ACOX2 mRNA CTD PMID:32068100 NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 increases expression EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of ACSL1 mRNA CTD PMID:30920876 PMID:33983380 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 increases expression EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of ACSL3 mRNA CTD PMID:30920876 PMID:33983380 NCBI chr 9:80,140,996...80,164,636
Ensembl chr 9:80,115,112...80,164,627
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 increases expression EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of ACSL4 mRNA CTD PMID:30920876 PMID:33983380 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of ANGPTL4 mRNA CTD PMID:30920876 PMID:33983380 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Aqp7 aquaporin 7 increases expression EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of AQP7 mRNA CTD PMID:30920876 PMID:33983380 NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:56,172,519...56,186,642
JBrowse link
G Atm ATM serine/threonine kinase decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of ATM mRNA CTD PMID:32790152 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Bad BCL2-associated agonist of cell death increases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of BAD mRNA CTD PMID:32790152 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bak1 BCL2-antagonist/killer 1 decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of BAK1 mRNA CTD PMID:32790152 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator affects expression
increases expression
ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid affects the expression of BAX mRNA
2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of BAX mRNA
CTD PMID:32068100 PMID:32790152 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of BCL2 mRNA CTD PMID:32790152 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of CCL2 mRNA CTD PMID:32790152 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of CCNB1 mRNA CTD PMID:32068100 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of CCNE1 mRNA CTD PMID:32068100 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of CCR1 mRNA CTD PMID:32790152 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Ccr3 C-C motif chemokine receptor 3 decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of CCR3 mRNA CTD PMID:32790152 NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990
JBrowse link
G Cd163 CD163 molecule decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of CD163 mRNA CTD PMID:32790152 NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878
JBrowse link
G Cdh1 cadherin 1 decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of CDH1 mRNA CTD PMID:32790152 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of CDK4 mRNA CTD PMID:32068100 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression EXP
ISO
2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of CPT1A mRNA CTD PMID:30920876 PMID:31676336 PMID:33983380 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B increases expression EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of CPT1B mRNA CTD PMID:30920876 PMID:33983380 NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 increases expression EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of CPT2 mRNA CTD PMID:30920876 PMID:33983380 NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
JBrowse link
G Ctnnb1 catenin beta 1 decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of CTNNB1 mRNA CTD PMID:32790152 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 increases expression EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of DGAT1 mRNA CTD PMID:30920876 PMID:33983380 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of DNMT3A mRNA CTD PMID:32068100 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of DNMT3B mRNA CTD PMID:32068100 NCBI chr 3:142,130,592...142,169,124
Ensembl chr 3:142,130,592...142,169,124
JBrowse link
G Dsc2 desmocollin 2 decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of DSC2 mRNA CTD PMID:32790152 NCBI chr18:11,450,392...11,482,476
Ensembl chr18:11,450,390...11,482,392
JBrowse link
G Ech1 enoyl-CoA hydratase 1 increases expression EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of ECH1 mRNA CTD PMID:30920876 PMID:33983380 NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase increases expression EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of EHHADH mRNA CTD PMID:30920876 PMID:33983380 NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
JBrowse link
G Ervfrd-1 endogenous retrovirus group FRD member 1, envelope decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of ERVFRD-1 mRNA CTD PMID:32790152 NCBI chr12:22,151,211...22,158,264
Ensembl chr12:22,151,211...22,158,264
JBrowse link
G Etfdh electron transfer flavoprotein dehydrogenase increases expression EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of ETFDH mRNA CTD PMID:30920876 NCBI chr 2:164,740,547...164,762,754
Ensembl chr 2:164,729,749...164,762,745
JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression
decreases expression
EXP
ISO
2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of FABP1 mRNA
2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of FABP1 mRNA
CTD PMID:30920876 PMID:32790152 PMID:33983380 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
JBrowse link
G Fabp5 fatty acid binding protein 5 increases expression EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of FABP5 mRNA CTD PMID:30920876 NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773
JBrowse link
G Fabp7 fatty acid binding protein 7 increases expression EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of FABP7 mRNA CTD PMID:33983380 NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880
JBrowse link
G Fads2 fatty acid desaturase 2 increases expression EXP
ISO
2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of FADS2 mRNA CTD PMID:30920876 PMID:32068100 PMID:33983380 NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
JBrowse link
G Folr1 folate receptor alpha decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of FOLR1 mRNA CTD PMID:32790152 NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667
JBrowse link
G Gk glycerol kinase increases expression EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of GK mRNA CTD PMID:30920876 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:50,163,123...50,238,631
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of HIF1A mRNA CTD PMID:32790152 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of HMGCR mRNA CTD PMID:32068100 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 increases expression EXP
ISO
2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of HMGCS2 mRNA CTD PMID:30920876 PMID:31676336 PMID:33983380 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of HMOX1 mRNA CTD PMID:32790152 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of HSPA5 mRNA CTD PMID:32790152 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of HSPD1 mRNA CTD PMID:30920876 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Il1a interleukin 1 alpha decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of IL1A mRNA CTD PMID:32790152 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1r1 interleukin 1 receptor type 1 decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of IL1R1 mRNA CTD PMID:32790152 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
JBrowse link
G Il6r interleukin 6 receptor decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of IL6R mRNA CTD PMID:32790152 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
JBrowse link
G Lmbrd1 LMBR1 domain containing 1 increases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of LMBRD1 mRNA CTD PMID:32790152 NCBI chr 9:27,096,387...27,178,095
Ensembl chr 9:27,096,297...27,178,090
JBrowse link
G Lpl lipoprotein lipase increases expression EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of LPL mRNA CTD PMID:30920876 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Mlycd malonyl-CoA decarboxylase increases expression EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of MLYCD mRNA CTD PMID:30920876 PMID:33983380 NCBI chr19:47,447,931...47,463,794
Ensembl chr19:47,447,970...47,463,793
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of MYC mRNA CTD PMID:32790152 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nfkbia NFKB inhibitor alpha decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of NFKBIA mRNA CTD PMID:32790152 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of NOS2 mRNA CTD PMID:32790152 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of NQO1 mRNA CTD PMID:32790152 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 increases expression EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of PCK1 mRNA CTD PMID:30920876 PMID:33983380 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of PCNA mRNA CTD PMID:32790152 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pgf placental growth factor decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of PGF mRNA CTD PMID:32790152 NCBI chr 6:104,816,102...104,826,685
Ensembl chr 6:104,816,104...104,826,685
JBrowse link
G Plin2 perilipin 2 increases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of PLIN2 mRNA CTD PMID:31676336 NCBI chr 5:101,156,643...101,211,738
Ensembl chr 5:101,154,411...101,242,319
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of PPARA mRNA CTD PMID:32790152 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of PPARD mRNA CTD PMID:32790152 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of PPARG mRNA CTD PMID:32790152 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha decreases expression EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of PPARGC1A mRNA CTD PMID:33983380 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Pyy peptide YY increases expression EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of PYY mRNA CTD PMID:33983380 NCBI chr10:87,061,155...87,062,278
Ensembl chr10:87,061,161...87,061,815
JBrowse link
G Rxrg retinoid X receptor gamma increases expression EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of RXRG mRNA CTD PMID:30920876 PMID:33983380 NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167
JBrowse link
G Scd stearoyl-CoA desaturase increases expression EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of SCD mRNA; 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of SCD1 mRNA CTD PMID:30920876 PMID:33983380 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Slc19a2 solute carrier family 19 member 2 decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of SLC19A2 mRNA CTD PMID:32790152 NCBI chr13:76,601,975...76,616,175
Ensembl chr13:76,601,900...76,616,172
JBrowse link
G Slc19a3 solute carrier family 19 member 3 decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of SLC19A3 mRNA CTD PMID:32790152 NCBI chr 9:84,275,722...84,299,368
Ensembl chr 9:84,277,024...84,299,337
JBrowse link
G Slc22a5 solute carrier family 22 member 5 increases expression EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of SLC22A5 mRNA CTD PMID:30920876 PMID:33983380 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309
JBrowse link
G Slc27a2 solute carrier family 27 member 2 increases expression EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of SLC27A2 mRNA CTD PMID:30920876 PMID:33983380 NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208
JBrowse link
G Slc27a4 solute carrier family 27 member 4 decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of SLC27A4 mRNA CTD PMID:32790152 NCBI chr 3:13,075,022...13,087,943
Ensembl chr 3:13,075,022...13,087,943
JBrowse link
G Slc30a1 solute carrier family 30 member 1 decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of SLC30A1 mRNA CTD PMID:32790152 NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910
JBrowse link
G Slc38a1 solute carrier family 38, member 1 decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of SLC38A1 mRNA CTD PMID:32790152 NCBI chr 7:127,733,230...127,802,541
Ensembl chr 7:127,738,226...127,802,218
JBrowse link
G Slc38a2 solute carrier family 38, member 2 decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of SLC38A2 mRNA CTD PMID:32790152 NCBI chr 7:127,851,267...127,863,482
Ensembl chr 7:127,851,267...127,863,436
JBrowse link
G Slc5a6 solute carrier family 5 member 6 decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of SLC5A6 mRNA CTD PMID:32790152 NCBI chr 6:25,319,187...25,331,713
Ensembl chr 6:25,320,442...25,331,712
JBrowse link
G Slc6a4 solute carrier family 6 member 4 decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of SLC6A4 mRNA CTD PMID:32790152 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
JBrowse link
G Snai1 snail family transcriptional repressor 1 decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of SNAI1 mRNA CTD PMID:32790152 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of TGFB1 mRNA CTD PMID:32790152 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of TGFBR1 mRNA CTD PMID:32790152 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Twist1 twist family bHLH transcription factor 1 decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of TWIST1 mRNA CTD PMID:32790152 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653
JBrowse link
G Txnip thioredoxin interacting protein increases expression EXP 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in increased expression of TXNIP mRNA CTD PMID:30920876 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link
G Vegfb vascular endothelial growth factor B decreases expression ISO 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid results in decreased expression of VEGFB mRNA CTD PMID:32790152 NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    chemical entity 19808
      atom 19807
        nonmetal atom 19694
          oxygen atom 19432
            oxygen molecular entity 19432
              organooxygen compound 19001
                ether 16911
                  2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid 88
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19807
      composite particle 19807
        hadron 19807
          baryon 19807
            nucleon 19807
              atomic nucleus 19807
                atom 19807
                  main group element atom 19704
                    p-block element atom 19704
                      carbon group element atom 19626
                        carbon atom 19616
                          organic molecular entity 19616
                            organic group 18725
                              organic divalent group 18716
                                organodiyl group 18716
                                  carbonyl group 18664
                                    carbonyl compound 18664
                                      carboxylic acid 18361
                                        monocarboxylic acid 17631
                                          2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid 88
paths to the root