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ONTOLOGY REPORT - ANNOTATIONS


Term:aldrithiol
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Accession:CHEBI:143170 term browser browse the term
Definition:A member of the class of pyridines that is pyridine which is substituted by a pyridin-2-yldisulfanediyl group at position 2. It is a reagent used in molecular biology as an oxidizing agent. Also used in peptide synthesis and for detecting thiols.
Synonyms:exact_synonym: 2,2'-disulfanediyldipyridine
 related_synonym: 2,2'-dipyridyl disulfide;   2,2'-dipyridyldisulphide;   2,2'-dithiobis-pyridine;   2,2'-dithiobispyridine;   2,2'-dithiodipyridine;   2,2'-pyridine disulfide;   2-dipyridyl disulfide;   2-pyridinyl disulfide;   Formula=C10H8N2S2;   InChI=1S/C10H8N2S2/c1-3-7-11-9(5-1)13-14-10-6-2-4-8-12-10/h1-8H;   InChIKey=HAXFWIACAGNFHA-UHFFFAOYSA-N;   SMILES=S(SC=1N=CC=CC1)C=2N=CC=CC2;   aldrithiol-2;   bis(2-pyridyl)disulfide;   di(2-pyridyl)disulfide
 xref: Beilstein:154629;   CAS:2127-03-9
 xref_mesh: MESH:C001105
 xref: PMID:11331359;   PMID:16998480;   PMID:17506610;   PMID:20965543;   PMID:22561701;   PMID:22807723;   PMID:23751221;   PMID:30597776;   Wikipedia:2\,2'-Dipyridyldisulfide


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aldrithiol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Nppa natriuretic peptide A JBrowse link 5 164,808,407 164,809,716 RGD:6480464
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A JBrowse link 7 51,404,971 51,515,382 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19758
    role 19705
      chemical role 19224
        oxidising agent 9266
          aldrithiol 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19758
    subatomic particle 19756
      composite particle 19756
        hadron 19756
          baryon 19756
            nucleon 19756
              atomic nucleus 19756
                atom 19756
                  main group element atom 19641
                    p-block element atom 19641
                      carbon group element atom 19532
                        carbon atom 19521
                          organic molecular entity 19521
                            organic molecule 19441
                              organic cyclic compound 19203
                                organic heterocyclic compound 18278
                                  organic heteromonocyclic compound 16404
                                    pyridines 8347
                                      aldrithiol 6
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.