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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2-acetamidophenol
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Accession:CHEBI:143107 term browser browse the term
Definition:A member of the class of phenols that is 2-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group. A positional isomer of paracetamol which possesses anti-inflammatory, anti-arthritic and anti-platelet aggregation properties.
Synonyms:related_synonym: 2-(N-acetylamino)phenol;   2-(acetylamino)phenol;   2-acetaminophenol;   2-hydroxyacetanilide;   Formula=C8H9NO2;   InChI=1S/C8H9NO2/c1-6(10)9-7-4-2-3-5-8(7)11/h2-5,11H,1H3,(H,9,10);   InChIKey=ADVGKWPZRIDURE-UHFFFAOYSA-N;   N-(2-hydroxyphenyl)acetamide;   N-acetyl-2-aminophenol;   N-acetyl-o-aminophenol;   SMILES=C1(=C(C=CC=C1)NC(=O)C)O;   acet-o-aminofenol;   o-(acetylamino)phenol;   o-acetamidophenol;   o-acetaminophenol;   o-acetylaminofenol;   o-hydroxyacetanilide
 xref: CAS:614-80-2;   HMDB:HMDB0061919
 xref_mesh: MESH:C047799
 xref: PDB:5Q1J;   PDBeChem:9KS;   PMID:20452462;   PMID:23971042;   PMID:24186846;   PMID:24370547;   PMID:24846408;   PMID:25663820;   PMID:28474155;   PMID:29790115;   Patent:US2005049229;   Reaxys:607592



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2-acetamidophenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO 2-hydroxyacetanilide results in increased expression of BAX mRNA; 2-hydroxyacetanilide results in increased expression of BAX protein CTD PMID:31207345 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO 2-hydroxyacetanilide results in decreased expression of BCL2 mRNA; 2-hydroxyacetanilide results in decreased expression of BCL2 protein CTD PMID:31207345 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19831
    role 19807
      application 19650
        anti-inflammatory agent 16605
          2-acetamidophenol 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19831
    subatomic particle 19829
      composite particle 19829
        hadron 19829
          baryon 19829
            nucleon 19829
              atomic nucleus 19829
                atom 19829
                  main group element atom 19779
                    p-block element atom 19779
                      carbon group element atom 19728
                        carbon atom 19724
                          organic molecular entity 19724
                            heteroorganic entity 19477
                              organochalcogen compound 19240
                                organooxygen compound 19155
                                  carbon oxoacid 18613
                                    carboxylic acid 18610
                                      carboacyl group 17699
                                        univalent carboacyl group 17699
                                          carbamoyl group 17549
                                            carboxamide 17549
                                              acetamides 14636
                                                2-acetamidophenol 2
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