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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:143107 term browser browse the term
Definition:A member of the class of phenols that is 2-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group. A positional isomer of paracetamol which possesses anti-inflammatory, anti-arthritic and anti-platelet aggregation properties.
Synonyms:related_synonym: 2-(N-acetylamino)phenol;   2-(acetylamino)phenol;   2-acetaminophenol;   2-hydroxyacetanilide;   Formula=C8H9NO2;   InChI=1S/C8H9NO2/c1-6(10)9-7-4-2-3-5-8(7)11/h2-5,11H,1H3,(H,9,10);   InChIKey=ADVGKWPZRIDURE-UHFFFAOYSA-N;   N-(2-hydroxyphenyl)acetamide;   N-acetyl-2-aminophenol;   N-acetyl-o-aminophenol;   SMILES=C1(=C(C=CC=C1)NC(=O)C)O;   acet-o-aminofenol;   o-(acetylamino)phenol;   o-acetamidophenol;   o-acetaminophenol;   o-acetylaminofenol;   o-hydroxyacetanilide
 xref: CAS:614-80-2;   HMDB:HMDB0061919
 xref_mesh: MESH:C047799
 xref: PDB:5Q1J;   PDBeChem:9KS;   PMID:20452462;   PMID:23971042;   PMID:24186846;   PMID:24370547;   PMID:24846408;   PMID:25663820;   PMID:28474155;   PMID:29790115;   Patent:US2005049229;   Reaxys:607592

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2-acetamidophenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO 2-hydroxyacetanilide results in increased expression of BAX mRNA; 2-hydroxyacetanilide results in increased expression of BAX protein CTD PMID:31207345 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO 2-hydroxyacetanilide results in decreased expression of BCL2 mRNA; 2-hydroxyacetanilide results in decreased expression of BCL2 protein CTD PMID:31207345 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19740
    role 19713
      application 19546
        anti-inflammatory agent 16471
          2-acetamidophenol 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19740
    subatomic particle 19738
      composite particle 19738
        hadron 19738
          baryon 19738
            nucleon 19738
              atomic nucleus 19738
                atom 19738
                  main group element atom 19686
                    p-block element atom 19686
                      carbon group element atom 19631
                        carbon atom 19627
                          organic molecular entity 19627
                            organic group 18846
                              organic divalent group 18832
                                organodiyl group 18832
                                  carbonyl group 18798
                                    carbonyl compound 18798
                                      carboxylic acid 18518
                                        carboacyl group 17656
                                          univalent carboacyl group 17656
                                            carbamoyl group 17497
                                              carboxamide 17497
                                                acetamides 14633
                                                  2-acetamidophenol 2
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