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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:143107 term browser browse the term
Definition:A member of the class of phenols that is 2-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group. A positional isomer of paracetamol which possesses anti-inflammatory, anti-arthritic and anti-platelet aggregation properties.
Synonyms:related_synonym: 2-(N-acetylamino)phenol;   2-(acetylamino)phenol;   2-acetaminophenol;   2-hydroxyacetanilide;   Formula=C8H9NO2;   InChI=1S/C8H9NO2/c1-6(10)9-7-4-2-3-5-8(7)11/h2-5,11H,1H3,(H,9,10);   InChIKey=ADVGKWPZRIDURE-UHFFFAOYSA-N;   N-(2-hydroxyphenyl)acetamide;   N-acetyl-2-aminophenol;   N-acetyl-o-aminophenol;   SMILES=C1(=C(C=CC=C1)NC(=O)C)O;   acet-o-aminofenol;   o-(acetylamino)phenol;   o-acetamidophenol;   o-acetaminophenol;   o-acetylaminofenol;   o-hydroxyacetanilide
 xref: CAS:614-80-2;   HMDB:HMDB0061919
 xref_mesh: MESH:C047799
 xref: PDB:5Q1J;   PDBeChem:9KS;   PMID:20452462;   PMID:23971042;   PMID:24186846;   PMID:24370547;   PMID:24846408;   PMID:25663820;   PMID:28474155;   PMID:29790115;   Patent:US2005049229;   Reaxys:607592

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2-acetamidophenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO 2-hydroxyacetanilide results in increased expression of BAX mRNA; 2-hydroxyacetanilide results in increased expression of BAX protein CTD PMID:31207345 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO 2-hydroxyacetanilide results in decreased expression of BCL2 mRNA; 2-hydroxyacetanilide results in decreased expression of BCL2 protein CTD PMID:31207345 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link

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Term Annotations click to browse term
  CHEBI ontology 19853
    role 19804
      application 19477
        anti-inflammatory agent 14977
          2-acetamidophenol 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19853
    subatomic particle 19851
      composite particle 19851
        hadron 19851
          baryon 19851
            nucleon 19851
              atomic nucleus 19851
                atom 19851
                  main group element atom 19744
                    p-block element atom 19744
                      carbon group element atom 19650
                        carbon atom 19639
                          organic molecular entity 19639
                            organic group 18550
                              organic divalent group 18541
                                organodiyl group 18541
                                  carbonyl group 18447
                                    carbonyl compound 18447
                                      carboxylic acid 18125
                                        carboacyl group 17383
                                          univalent carboacyl group 17383
                                            carbamoyl group 17166
                                              carboxamide 17166
                                                acetamides 12401
                                                  2-acetamidophenol 2
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