Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References FTP Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:glufosinate-P
go back to main search page
Accession:CHEBI:142852 term browser browse the term
Definition:A 2-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid that has S configuration at position 2. A glutamine synthetase inhibitor, it is used (generally as the corresponding ammonium or sodium salts, known as glufosinate-P-ammonium and glufosinate-P-sodium, respectively) as a herbicide to control annual weeds and grasses.
Synonyms:exact_synonym: (2S)-2-amino-4-[hydroxy(methyl)phosphinoyl]butyric acid;   (2S)-2-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid
 related_synonym: (+)-glufosinate;   (2S)-2-amino-4-(hydroxymethylphosphinyl)butanoic acid;   (2S)-glufosinate;   (S)-glufosinate;   (S)-phosphinothricin;   4-[hydroxy(methyl)phosphinoyl]-L-homoalanine;   Formula=C5H12NO4P;   InChI=1S/C5H12NO4P/c1-11(9,10)3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10)/t4-/m0/s1;   InChIKey=IAJOBQBIJHVGMQ-BYPYZUCNSA-N;   L-glufosinate;   SMILES=C([C@H](CCP(=O)(C)O)N)(O)=O;   phosphinothricin-P
 xref: CAS:35597-44-5;   KEGG:C04650;   PDBeChem:PPQ;   PPDB:1667;   Pesticides:glufosinate-p
 cyclic_relationship: is_enantiomer_of CHEBI:142853;   is_tautomer_of CHEBI:142856

show annotations for term's descendants           Sort by:
 
glufosinate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arc activity-regulated cytoskeleton-associated protein multiple interactions
increases expression		 ISO Dizocilpine Maleate inhibits the reaction [phosphinothricin results in increased expression of ARC mRNA] CTD PMID:30557575 NCBI chr 7:115,907,097...115,911,059
Ensembl chr 7:115,907,097...115,910,541 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO phosphinothricin results in increased expression of FOS protein CTD PMID:27031874 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299 		JBrowse link
G Gfap glial fibrillary acidic protein increases expression ISO phosphinothricin results in increased expression of GFAP mRNA; phosphinothricin results in increased expression of GFAP protein CTD PMID:27031874 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506 		JBrowse link
G Glul glutamate-ammonia ligase increases expression
multiple interactions		 ISO phosphinothricin results in increased expression of GLUL mRNA
phosphinothricin results in increased expression of and results in increased activity of GLUL protein		 CTD PMID:27031874 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229 		JBrowse link
G Nefh neurofilament heavy affects expression EXP phosphinothricin affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557 		JBrowse link
G Peg3 paternally expressed 3 decreases expression ISO phosphinothricin results in decreased expression of PEG3 mRNA CTD PMID:25477793 NCBI chr 1:70,210,810...70,237,450
Ensembl chr 1:70,222,964...70,237,443 		JBrowse link
G Pten phosphatase and tensin homolog affects expression ISO phosphinothricin affects the expression of PTEN mRNA CTD PMID:25477793 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      application 19393
        agrochemical 14436
          glufosinate-P 7
            glufosinate + 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic group 18495
                              organic divalent group 18488
                                organodiyl group 18488
                                  carbonyl group 18391
                                    carbonyl compound 18391
                                      carboxylic acid 18061
                                        amino acid 14072
                                          alpha-amino acid 11539
                                            non-proteinogenic alpha-amino acid 1541
                                              2-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid 7
                                                glufosinate-P 7
                                                  glufosinate + 7
paths to the root

Contact Us |  About Us |  License CC BY 4.0 |  Legal Disclaimer |  © Medical College of Wisconsin
NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.