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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:142852 term browser browse the term
Definition:A 2-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid that has S configuration at position 2. A glutamine synthetase inhibitor, it is used (generally as the corresponding ammonium or sodium salts, known as glufosinate-P-ammonium and glufosinate-P-sodium, respectively) as a herbicide to control annual weeds and grasses.
Synonyms:exact_synonym: (2S)-2-amino-4-[hydroxy(methyl)phosphinoyl]butyric acid;   (2S)-2-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid
 related_synonym: (+)-glufosinate;   (2S)-2-amino-4-(hydroxymethylphosphinyl)butanoic acid;   (2S)-glufosinate;   (S)-glufosinate;   (S)-phosphinothricin;   4-[hydroxy(methyl)phosphinoyl]-L-homoalanine;   Formula=C5H12NO4P;   InChI=1S/C5H12NO4P/c1-11(9,10)3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10)/t4-/m0/s1;   InChIKey=IAJOBQBIJHVGMQ-BYPYZUCNSA-N;   L-glufosinate;   SMILES=C([C@H](CCP(=O)(C)O)N)(O)=O;   phosphinothricin-P
 xref: CAS:35597-44-5;   KEGG:C04650;   PDBeChem:PPQ;   PPDB:1667;   Pesticides:glufosinate-p
 cyclic_relationship: is_enantiomer_of CHEBI:142853;   is_tautomer_of CHEBI:142856

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glufosinate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arc activity-regulated cytoskeleton-associated protein multiple interactions
increases expression
ISO Dizocilpine Maleate inhibits the reaction [phosphinothricin results in increased expression of ARC mRNA] CTD PMID:30557575 NCBI chr 7:115,907,097...115,911,059
Ensembl chr 7:115,907,097...115,910,541
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO phosphinothricin results in increased expression of FOS protein CTD PMID:27031874 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Gfap glial fibrillary acidic protein increases expression ISO phosphinothricin results in increased expression of GFAP mRNA; phosphinothricin results in increased expression of GFAP protein CTD PMID:27031874 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Glul glutamate-ammonia ligase increases expression
multiple interactions
ISO phosphinothricin results in increased expression of GLUL mRNA
phosphinothricin results in increased expression of and results in increased activity of GLUL protein
CTD PMID:27031874 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
JBrowse link
G Nefh neurofilament heavy affects expression EXP phosphinothricin affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Peg3 paternally expressed 3 decreases expression ISO phosphinothricin results in decreased expression of PEG3 mRNA CTD PMID:25477793 NCBI chr 1:70,210,810...70,237,450
Ensembl chr 1:70,222,964...70,237,443
JBrowse link
G Pten phosphatase and tensin homolog affects expression ISO phosphinothricin affects the expression of PTEN mRNA CTD PMID:25477793 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      application 19393
        agrochemical 14436
          glufosinate-P 7
            glufosinate + 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic group 18495
                              organic divalent group 18488
                                organodiyl group 18488
                                  carbonyl group 18391
                                    carbonyl compound 18391
                                      carboxylic acid 18061
                                        amino acid 14072
                                          alpha-amino acid 11539
                                            non-proteinogenic alpha-amino acid 1541
                                              2-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid 7
                                                glufosinate-P 7
                                                  glufosinate + 7
paths to the root


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