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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid
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Accession:CHEBI:142851 term browser browse the term
Definition:A non-proteinogenic alpha-amino acid that is 2-aminobutanoic acid which is substituted at position 4 by a hydroxy(methyl)phosphoryl group.
Synonyms:exact_synonym: 2-amino-4-[hydroxy(methyl)phosphoryl]butyric acid
 related_synonym: Formula=C5H12NO4P;   InChI=1S/C5H12NO4P/c1-11(9,10)3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);   InChIKey=IAJOBQBIJHVGMQ-UHFFFAOYSA-N;   SMILES=C(C(CCP(=O)(C)O)N)(O)=O;   phosphinothricin


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Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arc activity-regulated cytoskeleton-associated protein multiple interactions
increases expression
ISO Dizocilpine Maleate inhibits the reaction [phosphinothricin results in increased expression of ARC mRNA] CTD PMID:30557575 NCBI chr 7:115,907,097...115,911,059
Ensembl chr 7:115,907,097...115,910,541
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO phosphinothricin results in increased expression of FOS protein CTD PMID:27031874 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Gfap glial fibrillary acidic protein increases expression ISO phosphinothricin results in increased expression of GFAP mRNA; phosphinothricin results in increased expression of GFAP protein CTD PMID:27031874 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Glul glutamate-ammonia ligase increases expression
multiple interactions
ISO phosphinothricin results in increased expression of GLUL mRNA
phosphinothricin results in increased expression of and results in increased activity of GLUL protein
CTD PMID:27031874 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
JBrowse link
G Nefh neurofilament heavy chain affects expression EXP phosphinothricin affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Peg3 paternally expressed 3 decreases expression ISO phosphinothricin results in decreased expression of PEG3 mRNA CTD PMID:25477793 NCBI chr 1:70,210,810...70,237,450
Ensembl chr 1:70,222,964...70,237,443
JBrowse link
G Pten phosphatase and tensin homolog affects expression ISO phosphinothricin affects the expression of PTEN mRNA CTD PMID:25477793 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19771
    chemical entity 19771
      atom 19770
        nonmetal atom 19646
          phosphorus atom 9715
            phosphorus molecular entity 9715
              phosphorus oxoacids and derivatives 9702
                phosphinic acids 30
                  2-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid 7
                    (2R)-glufosinate + 7
                    glufosinate-P + 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19771
    subatomic particle 19770
      composite particle 19770
        hadron 19770
          baryon 19770
            nucleon 19770
              atomic nucleus 19770
                atom 19770
                  main group element atom 19658
                    p-block element atom 19658
                      carbon group element atom 19574
                        carbon atom 19564
                          organic molecular entity 19564
                            organic group 18599
                              organic divalent group 18590
                                organodiyl group 18590
                                  carbonyl group 18505
                                    carbonyl compound 18505
                                      carboxylic acid 18157
                                        amino acid 14113
                                          alpha-amino acid 11600
                                            non-proteinogenic alpha-amino acid 1563
                                              2-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid 7
                                                (2R)-glufosinate + 7
                                                glufosinate-P + 7
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