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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:spiroiminodihydantoin
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Accession:CHEBI:142623 term browser browse the term
Definition:An azaspiro compound that is 1,3,6,8-tetraazaspiro[4.4]non-6-ene which is substituted by oxo groups at positions 2, 4, and 9. Both enantiomers are highly mutagenic products resulting from the oxidation of guanine and 8-oxo-7,8-dihydroguanine in DNA by reactive oxygen species.
Synonyms:exact_synonym: 7-amino-1,3,6,8-tetraazaspiro[4.4]non-6-ene-2,4,9-trione
 related_synonym: Formula=C5H5N5O3;   InChI=1S/C5H5N5O3/c6-3-7-1(11)5(9-3)2(12)8-4(13)10-5/h(H3,6,7,9,11)(H2,8,10,12,13);   InChIKey=HJWQNCPSKFANJK-UHFFFAOYSA-N;   SMILES=N1C(NC(C12N=C(NC2=O)N)=O)=O
 xref: PMID:15540949;   PMID:17915881;   PMID:19146379;   PMID:19485408;   PMID:20014751;   PMID:23360616;   PMID:24649945;   PMID:26572218;   PMID:26807878;   PMID:27074396;   PMID:28230976;   PMID:28514164;   PMID:28845978;   PMID:30592213


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              spiroiminodihydantoin 0
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                atom 0
                  main group element atom 0
                    p-block element atom 0
                      carbon group element atom 0
                        carbon atom 0
                          organic molecular entity 0
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                              organic cyclic compound 0
                                organic heterocyclic compound 0
                                  organic heteromonocyclic compound 0
                                    diazolidine 0
                                      imidazolidines 0
                                        imidazolidinone 0
                                          imidazolidine-2,4-dione 0
                                            hydantoin 0
                                              spiroiminodihydantoin 0
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