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ONTOLOGY REPORT - ANNOTATIONS


Term:CMB4563
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Accession:CHEBI:142445 term browser browse the term
Definition:An imidazoquinoline that is 1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one which is substituted at positions 1, 3, and 8 by by p-(pyrrol-1-yl)phenyl, methyl, and pyridin-3-yl group, respectively. A potent and specific inhibitor of Target Of Rapamycin Complex 2 (TORC2).
Synonyms:related_synonym: 1-(4-(1H-pyrrol-1-yl)phenyl)-3-methyl-8-(pyridin-3-yl)-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one;   CMB-4563;   Formula=C26H19N5O;   InChI=1S/C26H19N5O/c1-29-24-17-28-23-11-6-18(19-5-4-12-27-16-19)15-22(23)25(24)31(26(29)32)21-9-7-20(8-10-21)30-13-2-3-14-30/h2-17H,1H3;   InChIKey=CQQZVRUJSYPEQY-UHFFFAOYSA-N;   SMILES=N1=C2C(C=C(C=C2)C3=CN=CC=C3)=C4C(=C1)N(C(N4C5=CC=C(C=C5)N6C=CC=C6)=O)C
 xref: PMID:28976958 "Europe PMC";   PMID:29895620 "Europe PMC";   Reaxys:33175572 "Reaxys"


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  CHEBI ontology 19654
    role 19598
      application 19220
        agrochemical 13316
          fertilizer 9526
            urea 4946
              ureas 4944
                phenylureas 1949
                  CMB4563 0
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  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
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          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
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                      carbon group element atom 19413
                        carbon atom 19405
                          organic molecular entity 19405
                            organic group 18331
                              organic divalent group 18321
                                organodiyl group 18321
                                  carbonyl group 18209
                                    carbonyl compound 18209
                                      carboxylic acid 17908
                                        carboacyl group 16930
                                          univalent carboacyl group 16930
                                            carbamoyl group 16610
                                              carboxamide 16610
                                                monocarboxylic acid amide 13174
                                                  urea 4946
                                                    ureas 4944
                                                      phenylureas 1949
                                                        CMB4563 0
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