Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:(2S)-1-(6-chloro-5-fluoroindol-1-yl)-propan-2-amine
go back to main search page
Accession:CHEBI:142183 term browser browse the term
Definition:A 1-(6-chloro-5-fluoroindol-1-yl)-propan-2-amine that has S configuration. A selective agonist for both the 5-hydroxytryptamine 2B (5-HT2B) and 5-hydroxytryptamine 2C (5-HT2C)serotonin receptor subtypes, commonly used as fumarate salt.
Synonyms:exact_synonym: (2S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine
 related_synonym: (1S)-2-(6-chloro-5-fluoroindol-1-yl)-1-methylethylamine;   (S)-2-(6-chloro-5-fluoro-indol-1-yl)-1-methyl-ethylamine;   (S)-2-(6-chloro-5-fluoroindol-1-yl)-1-methylethylamine;   (S)-6-chloro-5-fluoro-alpha-methyl-1H-indole-1-ethanamine;   Formula=C11H12ClFN2;   InChI=1S/C11H12ClFN2/c1-7(14)6-15-3-2-8-4-10(13)9(12)5-11(8)15/h2-5,7H,6,14H2,1H3/t7-/m0/s1;   InChIKey=XJJZQXUGLLXTHO-ZETCQYMHSA-N;   ORG 35030;   Ro-60-0175;   Ro60-0175;   SMILES=C[C@@H](CN1C=CC2=CC(=C(C=C21)Cl)F)N
 xref: LINCS:LSM-1601;   PMID:10219979 "Europe PMC";   PMID:10498829 "Europe PMC";   PMID:10814735 "Europe PMC";   PMID:10903970 "Europe PMC";   PMID:11105935 "Europe PMC";   PMID:11399662 "Europe PMC";   PMID:12604698 "Europe PMC";   PMID:14666118 "Europe PMC";   PMID:17473916 "Europe PMC";   PMID:17653111 "Europe PMC";   PMID:22342986 "Europe PMC";   PMID:23201361 "Europe PMC";   PMID:23535834 "Europe PMC";   PMID:28583411 "Europe PMC";   PMID:9225301 "Europe PMC";   PMID:9694950 "Europe PMC";   Patent:EP655440;   Reaxys:7795121 "Reaxys";   Wikipedia:Ro60-0175


show annotations for term's descendants       view all columns           Sort by:
 

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        pharmacological role 18684
          agonist 18015
            5-hydroxytryptamine 2B receptor agonist 0
              (2S)-1-(6-chloro-5-fluoroindol-1-yl)-propan-2-amine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic molecule 19343
                              organic cyclic compound 19093
                                organic heterocyclic compound 18157
                                  organic heteropolycyclic compound 17423
                                    organic heterobicyclic compound 15889
                                      benzopyrrole 5747
                                        indoles 5526
                                          1-(6-chloro-5-fluoroindol-1-yl)-propan-2-amine 0
                                            (2S)-1-(6-chloro-5-fluoroindol-1-yl)-propan-2-amine 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.