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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:N-ethyl-N-(2-hydroxyethyl)nitrosamine
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Accession:CHEBI:141568 term browser browse the term
Definition:A nitrosamine that is N-nitrosodiethylamine in which one of the ethyl froups has been replaced by a 2-hydroxyethyl group. It is used to induce renal and liver tumours in rodents.
Synonyms:exact_synonym: N-ethyl-N-(2-hydroxyethyl)nitrous amide
 related_synonym: 2-(ethylnitrosamino)ethanol;   Aethyl-aethanol-nitrosoamin;   EHEN;   Formula=C4H10N2O2;   InChI=1S/C4H10N2O2/c1-2-6(5-8)3-4-7/h7H,2-4H2,1H3;   InChIKey=HNQBPUIXFDQDRJ-UHFFFAOYSA-N;   N-Nitrosoaethylaethanolamin;   N-ethyl-N-hydroxyethylnitrosamine;   N-nitroso-N-ethyl-N-(2-hydroxyethyl)amine;   N-nitrosoethyl-2-hydroxyethylamine;   N-nitrosoethylethanolamine;   SMILES=CCN(CCO)N=O;   ethyl(hydroxyethyl)nitrosamine;   ethyl-2-hydroxyethylnitrosamine;   ethylethanolnitrosamine
 xref: CAS:13147-25-6
 xref_mesh: MESH:C023845
 xref: PMID:10211943;   PMID:10530782;   PMID:10799738;   PMID:11169143;   PMID:11421490;   PMID:11463489;   PMID:12127687;   PMID:19833912;   PMID:26538808;   PMID:4006078;   PMID:7812934;   PMID:7904986;   PMID:8578103;   PMID:8824538;   PMID:9500199;   PMID:9608641


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N-ethyl-N-(2-hydroxyethyl)nitrosamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gjb1 gap junction protein, beta 1 decreases expression EXP N-ethyl-N-hydroxyethylnitrosamine results in decreased expression of GJB1 mRNA CTD PMID:2559087 NCBI chr  X:66,501,848...66,509,783
Ensembl chr  X:66,501,820...66,509,925 		JBrowse link
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Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    role 19818
      biological role 19785
        aetiopathogenetic role 19163
          carcinogenic agent 18507
            N-ethyl-N-(2-hydroxyethyl)nitrosamine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    p-block element atom 19759
                      chalcogen 19515
                        oxygen atom 19520
                          oxygen molecular entity 19490
                            hydroxides 19300
                              organic hydroxy compound 18928
                                alcohol 15673
                                  primary alcohol 14643
                                    N-ethyl-N-(2-hydroxyethyl)nitrosamine 1
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