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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:N-ethyl-N-(2-hydroxyethyl)nitrosamine
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Accession:CHEBI:141568 term browser browse the term
Definition:A nitrosamine that is N-nitrosodiethylamine in which one of the ethyl froups has been replaced by a 2-hydroxyethyl group. It is used to induce renal and liver tumours in rodents.
Synonyms:exact_synonym: N-ethyl-N-(2-hydroxyethyl)nitrous amide
 related_synonym: 2-(ethylnitrosamino)ethanol;   Aethyl-aethanol-nitrosoamin;   EHEN;   Formula=C4H10N2O2;   InChI=1S/C4H10N2O2/c1-2-6(5-8)3-4-7/h7H,2-4H2,1H3;   InChIKey=HNQBPUIXFDQDRJ-UHFFFAOYSA-N;   N-Nitrosoaethylaethanolamin;   N-ethyl-N-hydroxyethylnitrosamine;   N-nitroso-N-ethyl-N-(2-hydroxyethyl)amine;   N-nitrosoethyl-2-hydroxyethylamine;   N-nitrosoethylethanolamine;   SMILES=CCN(CCO)N=O;   ethyl(hydroxyethyl)nitrosamine;   ethyl-2-hydroxyethylnitrosamine;   ethylethanolnitrosamine
 xref: CAS:13147-25-6
 xref_mesh: MESH:C023845
 xref: PMID:10211943;   PMID:10530782;   PMID:10799738;   PMID:11169143;   PMID:11421490;   PMID:11463489;   PMID:12127687;   PMID:19833912;   PMID:26538808;   PMID:4006078;   PMID:7812934;   PMID:7904986;   PMID:8578103;   PMID:8824538;   PMID:9500199;   PMID:9608641



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N-ethyl-N-(2-hydroxyethyl)nitrosamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gjb1 gap junction protein, beta 1 decreases expression EXP N-ethyl-N-hydroxyethylnitrosamine results in decreased expression of GJB1 mRNA CTD PMID:2559087 NCBI chr  X:66,501,848...66,509,783
Ensembl chr  X:66,501,820...66,509,925
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  CHEBI ontology 19800
    role 19751
      biological role 19751
        aetiopathogenetic role 19027
          carcinogenic agent 18362
            N-ethyl-N-(2-hydroxyethyl)nitrosamine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      chalcogen 19450
                        oxygen atom 19423
                          oxygen molecular entity 19423
                            hydroxides 19158
                              organic hydroxy compound 18656
                                alcohol 15085
                                  primary alcohol 14005
                                    N-ethyl-N-(2-hydroxyethyl)nitrosamine 1
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