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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:141568 term browser browse the term
Definition:A nitrosamine that is N-nitrosodiethylamine in which one of the ethyl froups has been replaced by a 2-hydroxyethyl group. It is used to induce renal and liver tumours in rodents.
Synonyms:exact_synonym: N-ethyl-N-(2-hydroxyethyl)nitrous amide
 related_synonym: 2-(ethylnitrosamino)ethanol;   Aethyl-aethanol-nitrosoamin;   EHEN;   Formula=C4H10N2O2;   InChI=1S/C4H10N2O2/c1-2-6(5-8)3-4-7/h7H,2-4H2,1H3;   InChIKey=HNQBPUIXFDQDRJ-UHFFFAOYSA-N;   N-Nitrosoaethylaethanolamin;   N-ethyl-N-hydroxyethylnitrosamine;   N-nitroso-N-ethyl-N-(2-hydroxyethyl)amine;   N-nitrosoethyl-2-hydroxyethylamine;   N-nitrosoethylethanolamine;   SMILES=CCN(CCO)N=O;   ethyl(hydroxyethyl)nitrosamine;   ethyl-2-hydroxyethylnitrosamine;   ethylethanolnitrosamine
 xref: CAS:13147-25-6
 xref_mesh: MESH:C023845
 xref: PMID:10211943;   PMID:10530782;   PMID:10799738;   PMID:11169143;   PMID:11421490;   PMID:11463489;   PMID:12127687;   PMID:19833912;   PMID:26538808;   PMID:4006078;   PMID:7812934;   PMID:7904986;   PMID:8578103;   PMID:8824538;   PMID:9500199;   PMID:9608641

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N-ethyl-N-(2-hydroxyethyl)nitrosamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gjb1 gap junction protein, beta 1 decreases expression EXP N-ethyl-N-hydroxyethylnitrosamine results in decreased expression of GJB1 mRNA CTD PMID:2559087 NCBI chr  X:71,272,030...71,279,973
Ensembl chr  X:71,272,042...71,279,977
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  CHEBI ontology 19883
    role 19833
      biological role 19833
        aetiopathogenetic role 19017
          carcinogenic agent 18373
            N-ethyl-N-(2-hydroxyethyl)nitrosamine 1
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  CHEBI ontology 19883
    subatomic particle 19881
      composite particle 19881
        hadron 19881
          baryon 19881
            nucleon 19881
              atomic nucleus 19881
                atom 19881
                  main group element atom 19771
                    p-block element atom 19771
                      chalcogen 19464
                        oxygen atom 19425
                          oxygen molecular entity 19425
                            hydroxides 19147
                              organic hydroxy compound 18696
                                alcohol 15040
                                  primary alcohol 13941
                                    N-ethyl-N-(2-hydroxyethyl)nitrosamine 1
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