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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:N-ethyl-N-(2-hydroxyethyl)nitrosamine
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Accession:CHEBI:141568 term browser browse the term
Definition:A nitrosamine that is N-nitrosodiethylamine in which one of the ethyl froups has been replaced by a 2-hydroxyethyl group. It is used to induce renal and liver tumours in rodents.
Synonyms:exact_synonym: N-ethyl-N-(2-hydroxyethyl)nitrous amide
 related_synonym: 2-(ethylnitrosamino)ethanol;   Aethyl-aethanol-nitrosoamin;   EHEN;   Formula=C4H10N2O2;   InChI=1S/C4H10N2O2/c1-2-6(5-8)3-4-7/h7H,2-4H2,1H3;   InChIKey=HNQBPUIXFDQDRJ-UHFFFAOYSA-N;   N-Nitrosoaethylaethanolamin;   N-ethyl-N-hydroxyethylnitrosamine;   N-nitroso-N-ethyl-N-(2-hydroxyethyl)amine;   N-nitrosoethyl-2-hydroxyethylamine;   N-nitrosoethylethanolamine;   SMILES=CCN(CCO)N=O;   ethyl(hydroxyethyl)nitrosamine;   ethyl-2-hydroxyethylnitrosamine;   ethylethanolnitrosamine
 xref: CAS:13147-25-6
 xref_mesh: MESH:C023845
 xref: PMID:10211943;   PMID:10530782;   PMID:10799738;   PMID:11169143;   PMID:11421490;   PMID:11463489;   PMID:12127687;   PMID:19833912;   PMID:26538808;   PMID:4006078;   PMID:7812934;   PMID:7904986;   PMID:8578103;   PMID:8824538;   PMID:9500199;   PMID:9608641


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N-ethyl-N-(2-hydroxyethyl)nitrosamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gjb1 gap junction protein, beta 1 decreases expression EXP N-ethyl-N-hydroxyethylnitrosamine results in decreased expression of GJB1 mRNA CTD PMID:2559087 NCBI chr  X:71,272,030...71,279,973
Ensembl chr  X:71,272,042...71,279,977
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  CHEBI ontology 19883
    role 19833
      biological role 19833
        aetiopathogenetic role 19017
          carcinogenic agent 18373
            N-ethyl-N-(2-hydroxyethyl)nitrosamine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19883
    subatomic particle 19881
      composite particle 19881
        hadron 19881
          baryon 19881
            nucleon 19881
              atomic nucleus 19881
                atom 19881
                  main group element atom 19771
                    p-block element atom 19771
                      chalcogen 19464
                        oxygen atom 19425
                          oxygen molecular entity 19425
                            hydroxides 19147
                              organic hydroxy compound 18696
                                alcohol 15040
                                  primary alcohol 13941
                                    N-ethyl-N-(2-hydroxyethyl)nitrosamine 1
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