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Accession:CHEBI:141568 term browser browse the term
Definition:A nitrosamine that is N-nitrosodiethylamine in which one of the ethyl froups has been replaced by a 2-hydroxyethyl group. It is used to induce renal and liver tumours in rodents.
Synonyms:exact_synonym: N-ethyl-N-(2-hydroxyethyl)nitrous amide
 related_synonym: 2-(ethylnitrosamino)ethanol;   Aethyl-aethanol-nitrosoamin;   EHEN;   Formula=C4H10N2O2;   InChI=1S/C4H10N2O2/c1-2-6(5-8)3-4-7/h7H,2-4H2,1H3;   InChIKey=HNQBPUIXFDQDRJ-UHFFFAOYSA-N;   N-Nitrosoaethylaethanolamin;   N-ethyl-N-hydroxyethylnitrosamine;   N-nitroso-N-ethyl-N-(2-hydroxyethyl)amine;   N-nitrosoethyl-2-hydroxyethylamine;   N-nitrosoethylethanolamine;   SMILES=CCN(CCO)N=O;   ethyl(hydroxyethyl)nitrosamine;   ethyl-2-hydroxyethylnitrosamine;   ethylethanolnitrosamine
 xref: CAS:13147-25-6 "ChemIDplus"
 xref_mesh: MESH:C023845
 xref: PMID:10211943 "Europe PMC";   PMID:10530782 "Europe PMC";   PMID:10799738 "Europe PMC";   PMID:11169143 "Europe PMC";   PMID:11421490 "Europe PMC";   PMID:11463489 "Europe PMC";   PMID:12127687 "Europe PMC";   PMID:19833912 "Europe PMC";   PMID:26538808 "Europe PMC";   PMID:4006078 "Europe PMC";   PMID:7812934 "Europe PMC";   PMID:7904986 "Europe PMC";   PMID:8578103 "Europe PMC";   PMID:8824538 "Europe PMC";   PMID:9500199 "Europe PMC";   PMID:9608641 "Europe PMC"

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N-ethyl-N-(2-hydroxyethyl)nitrosamine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gjb1 gap junction protein, beta 1 JBrowse link X 71,272,030 71,279,973 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19748
    role 19695
      biological role 19693
        aetiopathogenetic role 18796
          carcinogenic agent 17779
            N-ethyl-N-(2-hydroxyethyl)nitrosamine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19748
    subatomic particle 19744
      composite particle 19744
        hadron 19744
          baryon 19744
            nucleon 19744
              atomic nucleus 19744
                atom 19744
                  main group element atom 19628
                    p-block element atom 19628
                      chalcogen 19337
                        oxygen atom 19298
                          oxygen molecular entity 19298
                            hydroxides 19053
                              organic hydroxy compound 18626
                                alcohol 14947
                                  primary alcohol 13821
                                    N-ethyl-N-(2-hydroxyethyl)nitrosamine 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.