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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:tert-butyl ethyl ether
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Accession:CHEBI:141564 term browser browse the term
Definition:An ether having ethyl and tert-butyl as the two alkyl components. It is used as an engine fuel additive to reduce emissions of carbon monoxide and soot.
Synonyms:exact_synonym: 2-ethoxy-2-methylpropane
 related_synonym: 2-methyl-2-ethoxypropane;   ETBE;   Formula=C6H14O;   InChI=1S/C6H14O/c1-5-7-6(2,3)4/h5H2,1-4H3;   InChIKey=NUMQCACRALPSHD-UHFFFAOYSA-N;   SMILES=CCOC(C)(C)C;   t-BuOEt;   t-butyl ethyl ether
 xref: CAS:637-92-3;   Chemspider:11996
 xref_mesh: MESH:C098546
 xref: PMID:20544807;   PMID:21288640;   PMID:22177017;   PMID:23474617;   PMID:25108826;   PMID:25559863;   PMID:25644031;   PMID:26538808;   PMID:28152311;   PMID:28279869;   PMID:29478141;   Reaxys:1731469;   Wikipedia:Ethyl_tert-butyl_ether



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tert-butyl ethyl ether term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acox1 acyl-Coenzyme A oxidase 1, palmitoyl increases expression ISO ethyl tert-butyl ether results in increased expression of ACOX1 protein CTD PMID:24090815 NCBI chr11:116,062,714...116,089,605
Ensembl chr11:116,062,714...116,089,871
JBrowse link
G Aldh2 aldehyde dehydrogenase 2, mitochondrial affects response to substance
decreases response to substance
EXP ALDH2 protein affects the susceptibility to ethyl tert-butyl ether
ALDH2 results in decreased susceptibility to ethyl tert-butyl ether
CTD PMID:22102104 PMID:23810710 PMID:24448831 NCBI chr 5:121,704,090...121,731,887
Ensembl chr 5:121,704,090...121,731,887
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO ethyl tert-butyl ether results in increased expression of CCND1 mRNA CTD PMID:24090815 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
JBrowse link
G Ces3b carboxylesterase 3B increases expression ISO ethyl tert-butyl ether results in increased expression of CES3 protein CTD PMID:24090815 NCBI chr 8:105,810,365...105,820,561
Ensembl chr 8:105,810,385...105,820,561
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO ethyl tert-butyl ether results in increased expression of CYP1A1 mRNA; ethyl tert-butyl ether results in increased expression of CYP1A1 protein CTD PMID:24090815 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp2a5 cytochrome P450, family 2, subfamily a, polypeptide 5 increases metabolic processing ISO CYP2A6 protein results in increased metabolism of ethyl tert-butyl ether CTD PMID:11504148 NCBI chr 7:26,534,764...26,542,689
Ensembl chr 7:26,534,730...26,542,973
JBrowse link
G Cyp2b13 cytochrome P450, family 2, subfamily b, polypeptide 13 increases expression ISO ethyl tert-butyl ether results in increased expression of CYP2B2 mRNA CTD PMID:24090815 NCBI chr 7:25,760,813...25,795,622
Ensembl chr 7:25,760,922...25,795,622
JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 increases expression ISO ethyl tert-butyl ether results in increased expression of CYP2C6V1 mRNA; ethyl tert-butyl ether results in increased expression of CYP2C6V1 protein CTD PMID:24090815 NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression ISO ethyl tert-butyl ether results in increased expression of CYP2E1 mRNA; ethyl tert-butyl ether results in increased expression of CYP2E1 protein CTD PMID:24090815 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
JBrowse link
G Cyp2g1 cytochrome P450, family 2, subfamily g, polypeptide 1 increases expression ISO ethyl tert-butyl ether results in increased expression of CYP2G1 protein CTD PMID:24090815 NCBI chr 7:26,508,352...26,520,622
Ensembl chr 7:26,508,317...26,520,630
JBrowse link
G Ech1 enoyl coenzyme A hydratase 1, peroxisomal increases expression ISO ethyl tert-butyl ether results in increased expression of ECH1 protein CTD PMID:24090815 NCBI chr 7:28,524,763...28,531,664
Ensembl chr 7:28,524,642...28,531,672
JBrowse link
G Ephx1 epoxide hydrolase 1, microsomal increases expression ISO ethyl tert-butyl ether results in increased expression of EPHX1 protein CTD PMID:24090815 NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469
JBrowse link
G Fdx1 ferredoxin 1 increases expression ISO ethyl tert-butyl ether results in increased expression of FDX1 protein CTD PMID:24090815 NCBI chr 9:51,854,323...51,874,902
Ensembl chr 9:51,854,606...51,874,856
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression ISO ethyl tert-butyl ether results in increased expression of GPX1 protein CTD PMID:24090815 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
JBrowse link
G Gsta1 glutathione S-transferase, alpha 1 (Ya) increases expression ISO ethyl tert-butyl ether results in increased expression of GSTA5 protein CTD PMID:24090815 NCBI chr 9:78,137,951...78,149,965
Ensembl chr 9:78,137,938...78,149,966
JBrowse link
G Ogg1 8-oxoguanine DNA-glycosylase 1 decreases expression ISO ethyl tert-butyl ether results in decreased expression of OGG1 mRNA CTD PMID:24090815 NCBI chr 6:113,303,959...113,311,149
Ensembl chr 6:113,303,933...113,312,029
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression ISO ethyl tert-butyl ether results in increased expression of POR protein CTD PMID:24090815 NCBI chr 5:135,698,894...135,764,180
Ensembl chr 5:135,698,887...135,764,180
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression ISO ethyl tert-butyl ether results in increased expression of PPARA mRNA CTD PMID:24090815 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma increases expression ISO ethyl tert-butyl ether results in increased expression of PPARG mRNA CTD PMID:24090815 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Rbp4 retinol binding protein 4, plasma increases expression ISO ethyl tert-butyl ether results in increased expression of RBP4 protein CTD PMID:24090815 NCBI chr19:38,105,068...38,113,769
Ensembl chr19:38,105,077...38,113,729
JBrowse link
G Slc27a2 solute carrier family 27 (fatty acid transporter), member 2 increases expression ISO ethyl tert-butyl ether results in increased expression of SLC27A2 protein CTD PMID:24090815 NCBI chr 2:126,394,944...126,430,163
Ensembl chr 2:126,394,327...126,430,163
JBrowse link
G Slc27a5 solute carrier family 27 (fatty acid transporter), member 5 increases expression ISO ethyl tert-butyl ether results in increased expression of SLC27A5 protein CTD PMID:24090815 NCBI chr 7:12,722,273...12,732,119
Ensembl chr 7:12,722,273...12,732,119
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial increases expression ISO ethyl tert-butyl ether results in increased expression of SOD2 protein CTD PMID:24090815 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
JBrowse link
G Ugdh UDP-glucose dehydrogenase increases expression ISO ethyl tert-butyl ether results in increased expression of UGDH protein CTD PMID:24090815 NCBI chr 5:65,570,550...65,593,185
Ensembl chr 5:65,570,564...65,593,292
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 decreases expression ISO ethyl tert-butyl ether results in decreased expression of UGT1A1 mRNA CTD PMID:24090815 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719
JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 increases expression ISO ethyl tert-butyl ether results in increased expression of UGT2B1 protein CTD PMID:24090815 NCBI chr 5:87,064,498...87,074,362
Ensembl chr 5:87,064,497...87,074,389
JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 increases expression ISO ethyl tert-butyl ether results in increased expression of UQCRC1 protein CTD PMID:24090815 NCBI chr 9:108,765,716...108,778,709
Ensembl chr 9:108,765,701...108,778,691
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22188
    role 22173
      chemical role 21415
        fuel additive 3248
          tert-butyl ethyl ether 27
Path 2
Term Annotations click to browse term
  CHEBI ontology 22188
    subatomic particle 22180
      composite particle 22180
        hadron 22180
          baryon 22180
            nucleon 22180
              atomic nucleus 22180
                atom 22180
                  main group element atom 22114
                    p-block element atom 22114
                      carbon group element atom 21915
                        carbon atom 21840
                          organic molecular entity 21840
                            heteroorganic entity 21489
                              organochalcogen compound 20972
                                organooxygen compound 20809
                                  ether 18196
                                    tert-butyl ethyl ether 27
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