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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:tert-butyl ethyl ether
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Accession:CHEBI:141564 term browser browse the term
Definition:An ether having ethyl and tert-butyl as the two alkyl components. It is used as an engine fuel additive to reduce emissions of carbon monoxide and soot.
Synonyms:exact_synonym: 2-ethoxy-2-methylpropane
 related_synonym: 2-methyl-2-ethoxypropane;   ETBE;   Formula=C6H14O;   InChI=1S/C6H14O/c1-5-7-6(2,3)4/h5H2,1-4H3;   InChIKey=NUMQCACRALPSHD-UHFFFAOYSA-N;   SMILES=CCOC(C)(C)C;   t-BuOEt;   t-butyl ethyl ether
 xref: CAS:637-92-3;   Chemspider:11996
 xref_mesh: MESH:C098546
 xref: PMID:20544807;   PMID:21288640;   PMID:22177017;   PMID:23474617;   PMID:25108826;   PMID:25559863;   PMID:25644031;   PMID:26538808;   PMID:28152311;   PMID:28279869;   PMID:29478141;   Reaxys:1731469;   Wikipedia:Ethyl_tert-butyl_ether



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tert-butyl ethyl ether term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acox1 acyl-CoA oxidase 1 increases expression EXP ethyl tert-butyl ether results in increased expression of ACOX1 protein CTD PMID:24090815 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases response to substance
affects response to substance
ISO ALDH2 results in decreased susceptibility to ethyl tert-butyl ether
ALDH2 protein affects the susceptibility to ethyl tert-butyl ether
CTD PMID:22102104 PMID:23810710 PMID:24448831 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Ccnd1 cyclin D1 increases expression EXP ethyl tert-butyl ether results in increased expression of CCND1 mRNA CTD PMID:24090815 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ces3a carboxylesterase 3a increases expression EXP ethyl tert-butyl ether results in increased expression of CES3 protein CTD PMID:24090815 NCBI chr19:32,992,386...33,000,562 JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP ethyl tert-butyl ether results in increased expression of CYP1A1 mRNA; ethyl tert-butyl ether results in increased expression of CYP1A1 protein CTD PMID:24090815 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP ethyl tert-butyl ether results in increased expression of CYP2B1 mRNA CTD PMID:24090815 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP ethyl tert-butyl ether results in increased expression of CYP2B2 mRNA CTD PMID:24090815 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 increases expression EXP ethyl tert-butyl ether results in increased expression of CYP2C6V1 mRNA; ethyl tert-butyl ether results in increased expression of CYP2C6V1 protein CTD PMID:24090815 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP ethyl tert-butyl ether results in increased expression of CYP2E1 mRNA; ethyl tert-butyl ether results in increased expression of CYP2E1 protein CTD PMID:24090815 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp2g1 cytochrome P450, family 2, subfamily g, polypeptide 1 increases expression EXP ethyl tert-butyl ether results in increased expression of CYP2G1 protein CTD PMID:24090815 NCBI chr 1:82,145,635...82,156,862
Ensembl chr 1:82,145,073...82,156,828
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression EXP ethyl tert-butyl ether results in increased expression of CYP3A2 protein CTD PMID:24090815 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP ethyl tert-butyl ether results in increased expression of CYP3A23-3A1 mRNA; ethyl tert-butyl ether results in increased expression of CYP3A23-3A1 protein CTD PMID:24090815 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 increases expression EXP ethyl tert-butyl ether results in increased expression of CYP4A2 protein CTD PMID:24090815 NCBI chr 5:128,922,355...128,934,188
Ensembl chr 5:128,923,615...128,934,165
JBrowse link
G Ech1 enoyl-CoA hydratase 1 increases expression EXP ethyl tert-butyl ether results in increased expression of ECH1 protein CTD PMID:24090815 NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP ethyl tert-butyl ether results in increased expression of EPHX1 protein CTD PMID:24090815 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Fdx1 ferredoxin 1 increases expression EXP ethyl tert-butyl ether results in increased expression of FDX1 protein CTD PMID:24090815 NCBI chr 8:52,268,536...52,287,344
Ensembl chr 8:52,268,536...52,287,414
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression EXP ethyl tert-butyl ether results in increased expression of GPX1 protein CTD PMID:24090815 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 increases expression EXP ethyl tert-butyl ether results in increased expression of GSTA1 protein CTD PMID:24090815 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression EXP ethyl tert-butyl ether results in increased expression of GSTA3 protein CTD PMID:24090815 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression EXP ethyl tert-butyl ether results in increased expression of GSTA5 protein CTD PMID:24090815 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase decreases expression EXP ethyl tert-butyl ether results in decreased expression of OGG1 mRNA CTD PMID:24090815 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression EXP ethyl tert-butyl ether results in increased expression of POR protein CTD PMID:24090815 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression EXP ethyl tert-butyl ether results in increased expression of PPARA mRNA CTD PMID:24090815 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression EXP ethyl tert-butyl ether results in increased expression of PPARG mRNA CTD PMID:24090815 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Rbp4 retinol binding protein 4 increases expression EXP ethyl tert-butyl ether results in increased expression of RBP4 protein CTD PMID:24090815 NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399
JBrowse link
G Slc27a2 solute carrier family 27 member 2 increases expression EXP ethyl tert-butyl ether results in increased expression of SLC27A2 protein CTD PMID:24090815 NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208
JBrowse link
G Slc27a5 solute carrier family 27 member 5 increases expression EXP ethyl tert-butyl ether results in increased expression of SLC27A5 protein CTD PMID:24090815 NCBI chr 1:73,616,556...73,627,149
Ensembl chr 1:73,616,564...73,627,172
JBrowse link
G Sod2 superoxide dismutase 2 increases expression EXP ethyl tert-butyl ether results in increased expression of SOD2 protein CTD PMID:24090815 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase increases expression EXP ethyl tert-butyl ether results in increased expression of UGDH protein CTD PMID:24090815 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 decreases expression EXP ethyl tert-butyl ether results in decreased expression of UGT1A1 mRNA CTD PMID:24090815 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 increases expression EXP ethyl tert-butyl ether results in increased expression of UGT2B1 protein CTD PMID:24090815 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 increases expression EXP ethyl tert-butyl ether results in increased expression of UQCRC1 protein CTD PMID:24090815 NCBI chr 8:109,589,735...109,601,481
Ensembl chr 8:109,589,706...109,601,480
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    role 19894
      chemical role 19512
        fuel additive 3250
          tert-butyl ethyl ether 32
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            heteroorganic entity 19548
                              organochalcogen compound 19303
                                organooxygen compound 19217
                                  ether 17308
                                    tert-butyl ethyl ether 32
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