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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:tert-butyl ethyl ether
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Accession:CHEBI:141564 term browser browse the term
Definition:An ether having ethyl and tert-butyl as the two alkyl components. It is used as an engine fuel additive to reduce emissions of carbon monoxide and soot.
Synonyms:exact_synonym: 2-ethoxy-2-methylpropane
 related_synonym: 2-methyl-2-ethoxypropane;   ETBE;   Formula=C6H14O;   InChI=1S/C6H14O/c1-5-7-6(2,3)4/h5H2,1-4H3;   InChIKey=NUMQCACRALPSHD-UHFFFAOYSA-N;   SMILES=CCOC(C)(C)C;   t-BuOEt;   t-butyl ethyl ether
 xref: CAS:637-92-3;   Chemspider:11996
 xref_mesh: MESH:C098546
 xref: PMID:20544807;   PMID:21288640;   PMID:22177017;   PMID:23474617;   PMID:25108826;   PMID:25559863;   PMID:25644031;   PMID:26538808;   PMID:28152311;   PMID:28279869;   PMID:29478141;   Reaxys:1731469;   Wikipedia:Ethyl_tert-butyl_ether


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tert-butyl ethyl ether term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acox1 acyl-CoA oxidase 1 increases expression EXP ethyl tert-butyl ether results in increased expression of ACOX1 protein CTD PMID:24090815 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases response to substance
affects response to substance
ISO ALDH2 results in decreased susceptibility to ethyl tert-butyl ether
ALDH2 protein affects the susceptibility to ethyl tert-butyl ether
CTD PMID:22102104 PMID:23810710 PMID:24448831 NCBI chr12:34,949,549...34,982,527 JBrowse link
G Ccnd1 cyclin D1 increases expression EXP ethyl tert-butyl ether results in increased expression of CCND1 mRNA CTD PMID:24090815 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ces3a carboxylesterase 3a increases expression EXP ethyl tert-butyl ether results in increased expression of CES3 protein CTD PMID:24090815 NCBI chr19:32,992,386...33,000,562 JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP ethyl tert-butyl ether results in increased expression of CYP1A1 mRNA; ethyl tert-butyl ether results in increased expression of CYP1A1 protein CTD PMID:24090815 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP ethyl tert-butyl ether results in increased expression of CYP2B1 mRNA CTD PMID:24090815 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP ethyl tert-butyl ether results in increased expression of CYP2B2 mRNA CTD PMID:24090815 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 increases expression EXP ethyl tert-butyl ether results in increased expression of CYP2C6V1 mRNA; ethyl tert-butyl ether results in increased expression of CYP2C6V1 protein CTD PMID:24090815 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP ethyl tert-butyl ether results in increased expression of CYP2E1 mRNA; ethyl tert-butyl ether results in increased expression of CYP2E1 protein CTD PMID:24090815 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp2g1 cytochrome P450, family 2, subfamily g, polypeptide 1 increases expression EXP ethyl tert-butyl ether results in increased expression of CYP2G1 protein CTD PMID:24090815 NCBI chr 1:82,145,635...82,156,862
Ensembl chr 1:82,145,073...82,156,828
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression EXP ethyl tert-butyl ether results in increased expression of CYP3A2 protein CTD PMID:24090815 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP ethyl tert-butyl ether results in increased expression of CYP3A23-3A1 mRNA; ethyl tert-butyl ether results in increased expression of CYP3A23-3A1 protein CTD PMID:24090815 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 increases expression EXP ethyl tert-butyl ether results in increased expression of CYP4A2 protein CTD PMID:24090815 NCBI chr 5:128,922,355...128,934,188
Ensembl chr 5:128,923,615...128,934,165
JBrowse link
G Ech1 enoyl-CoA hydratase 1 increases expression EXP ethyl tert-butyl ether results in increased expression of ECH1 protein CTD PMID:24090815 NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP ethyl tert-butyl ether results in increased expression of EPHX1 protein CTD PMID:24090815 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Fdx1 ferredoxin 1 increases expression EXP ethyl tert-butyl ether results in increased expression of FDX1 protein CTD PMID:24090815 NCBI chr 8:52,268,536...52,287,344
Ensembl chr 8:52,268,536...52,287,414
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression EXP ethyl tert-butyl ether results in increased expression of GPX1 protein CTD PMID:24090815 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 increases expression EXP ethyl tert-butyl ether results in increased expression of GSTA1 protein CTD PMID:24090815 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression EXP ethyl tert-butyl ether results in increased expression of GSTA3 protein CTD PMID:24090815 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression EXP ethyl tert-butyl ether results in increased expression of GSTA5 protein CTD PMID:24090815 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase decreases expression EXP ethyl tert-butyl ether results in decreased expression of OGG1 mRNA CTD PMID:24090815 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression EXP ethyl tert-butyl ether results in increased expression of POR protein CTD PMID:24090815 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression EXP ethyl tert-butyl ether results in increased expression of PPARA mRNA CTD PMID:24090815 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression EXP ethyl tert-butyl ether results in increased expression of PPARG mRNA CTD PMID:24090815 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Rbp4 retinol binding protein 4 increases expression EXP ethyl tert-butyl ether results in increased expression of RBP4 protein CTD PMID:24090815 NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399
JBrowse link
G Slc27a2 solute carrier family 27 member 2 increases expression EXP ethyl tert-butyl ether results in increased expression of SLC27A2 protein CTD PMID:24090815 NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208
JBrowse link
G Slc27a5 solute carrier family 27 member 5 increases expression EXP ethyl tert-butyl ether results in increased expression of SLC27A5 protein CTD PMID:24090815 NCBI chr 1:73,616,556...73,627,149
Ensembl chr 1:73,616,564...73,627,172
JBrowse link
G Sod2 superoxide dismutase 2 increases expression EXP ethyl tert-butyl ether results in increased expression of SOD2 protein CTD PMID:24090815 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase increases expression EXP ethyl tert-butyl ether results in increased expression of UGDH protein CTD PMID:24090815 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 decreases expression EXP ethyl tert-butyl ether results in decreased expression of UGT1A1 mRNA CTD PMID:24090815 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 increases expression EXP ethyl tert-butyl ether results in increased expression of UGT2B1 protein CTD PMID:24090815 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 increases expression EXP ethyl tert-butyl ether results in increased expression of UQCRC1 protein CTD PMID:24090815 NCBI chr 8:109,589,735...109,601,481
Ensembl chr 8:109,589,706...109,601,480
JBrowse link

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  CHEBI ontology 19812
    role 19761
      chemical role 19336
        fuel additive 3116
          tert-butyl ethyl ether 32
Path 2
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  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      carbon group element atom 19630
                        carbon atom 19620
                          organic molecular entity 19620
                            heteroorganic entity 19283
                              organochalcogen compound 19054
                                organooxygen compound 19004
                                  ether 16912
                                    tert-butyl ethyl ether 32
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