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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:tert-butyl ethyl ether
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Accession:CHEBI:141564 term browser browse the term
Definition:An ether having ethyl and tert-butyl as the two alkyl components. It is used as an engine fuel additive to reduce emissions of carbon monoxide and soot.
Synonyms:exact_synonym: 2-ethoxy-2-methylpropane
 related_synonym: 2-methyl-2-ethoxypropane;   ETBE;   Formula=C6H14O;   InChI=1S/C6H14O/c1-5-7-6(2,3)4/h5H2,1-4H3;   InChIKey=NUMQCACRALPSHD-UHFFFAOYSA-N;   SMILES=CCOC(C)(C)C;   t-BuOEt;   t-butyl ethyl ether
 xref: CAS:637-92-3;   Chemspider:11996
 xref_mesh: MESH:C098546
 xref: PMID:20544807;   PMID:21288640;   PMID:22177017;   PMID:23474617;   PMID:25108826;   PMID:25559863;   PMID:25644031;   PMID:26538808;   PMID:28152311;   PMID:28279869;   PMID:29478141;   Reaxys:1731469;   Wikipedia:Ethyl_tert-butyl_ether


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tert-butyl ethyl ether term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acox1 acyl-CoA oxidase 1 increases expression EXP ethyl tert-butyl ether results in increased expression of ACOX1 protein CTD PMID:24090815 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases response to substance
affects response to substance		 ISO ALDH2 results in decreased susceptibility to ethyl tert-butyl ether
ALDH2 protein affects the susceptibility to ethyl tert-butyl ether		 CTD PMID:22102104 PMID:23810710 PMID:24448831 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Ccnd1 cyclin D1 increases expression EXP ethyl tert-butyl ether results in increased expression of CCND1 mRNA CTD PMID:24090815 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ces3a carboxylesterase 3a increases expression EXP ethyl tert-butyl ether results in increased expression of CES3 protein CTD PMID:24090815 NCBI chr19:32,992,386...33,000,562 JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP ethyl tert-butyl ether results in increased expression of CYP1A1 mRNA; ethyl tert-butyl ether results in increased expression of CYP1A1 protein CTD PMID:24090815 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP ethyl tert-butyl ether results in increased expression of CYP2B1 mRNA CTD PMID:24090815 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP ethyl tert-butyl ether results in increased expression of CYP2B2 mRNA CTD PMID:24090815 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566 		JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 increases expression EXP ethyl tert-butyl ether results in increased expression of CYP2C6V1 mRNA; ethyl tert-butyl ether results in increased expression of CYP2C6V1 protein CTD PMID:24090815 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP ethyl tert-butyl ether results in increased expression of CYP2E1 mRNA; ethyl tert-butyl ether results in increased expression of CYP2E1 protein CTD PMID:24090815 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp2g1 cytochrome P450, family 2, subfamily g, polypeptide 1 increases expression EXP ethyl tert-butyl ether results in increased expression of CYP2G1 protein CTD PMID:24090815 NCBI chr 1:82,145,635...82,156,862
Ensembl chr 1:82,145,073...82,156,828 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression EXP ethyl tert-butyl ether results in increased expression of CYP3A2 protein CTD PMID:24090815 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP ethyl tert-butyl ether results in increased expression of CYP3A23-3A1 mRNA; ethyl tert-butyl ether results in increased expression of CYP3A23-3A1 protein CTD PMID:24090815 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030 		JBrowse link
G Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 increases expression EXP ethyl tert-butyl ether results in increased expression of CYP4A2 protein CTD PMID:24090815 NCBI chr 5:128,922,355...128,934,188
Ensembl chr 5:128,923,615...128,934,165 		JBrowse link
G Ech1 enoyl-CoA hydratase 1 increases expression EXP ethyl tert-butyl ether results in increased expression of ECH1 protein CTD PMID:24090815 NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795 		JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP ethyl tert-butyl ether results in increased expression of EPHX1 protein CTD PMID:24090815 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Fdx1 ferredoxin 1 increases expression EXP ethyl tert-butyl ether results in increased expression of FDX1 protein CTD PMID:24090815 NCBI chr 8:52,268,536...52,287,344
Ensembl chr 8:52,268,536...52,287,414 		JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression EXP ethyl tert-butyl ether results in increased expression of GPX1 protein CTD PMID:24090815 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 increases expression EXP ethyl tert-butyl ether results in increased expression of GSTA1 protein CTD PMID:24090815 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121 		JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression EXP ethyl tert-butyl ether results in increased expression of GSTA3 protein CTD PMID:24090815 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240 		JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression EXP ethyl tert-butyl ether results in increased expression of GSTA5 protein CTD PMID:24090815 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase decreases expression EXP ethyl tert-butyl ether results in decreased expression of OGG1 mRNA CTD PMID:24090815 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766 		JBrowse link
G Por cytochrome p450 oxidoreductase increases expression EXP ethyl tert-butyl ether results in increased expression of POR protein CTD PMID:24090815 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression EXP ethyl tert-butyl ether results in increased expression of PPARA mRNA CTD PMID:24090815 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression EXP ethyl tert-butyl ether results in increased expression of PPARG mRNA CTD PMID:24090815 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Rbp4 retinol binding protein 4 increases expression EXP ethyl tert-butyl ether results in increased expression of RBP4 protein CTD PMID:24090815 NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399 		JBrowse link
G Slc27a2 solute carrier family 27 member 2 increases expression EXP ethyl tert-butyl ether results in increased expression of SLC27A2 protein CTD PMID:24090815 NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208 		JBrowse link
G Slc27a5 solute carrier family 27 member 5 increases expression EXP ethyl tert-butyl ether results in increased expression of SLC27A5 protein CTD PMID:24090815 NCBI chr 1:73,616,556...73,627,149
Ensembl chr 1:73,616,564...73,627,172 		JBrowse link
G Sod2 superoxide dismutase 2 increases expression EXP ethyl tert-butyl ether results in increased expression of SOD2 protein CTD PMID:24090815 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase increases expression EXP ethyl tert-butyl ether results in increased expression of UGDH protein CTD PMID:24090815 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 decreases expression EXP ethyl tert-butyl ether results in decreased expression of UGT1A1 mRNA CTD PMID:24090815 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 increases expression EXP ethyl tert-butyl ether results in increased expression of UGT2B1 protein CTD PMID:24090815 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986 		JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 increases expression EXP ethyl tert-butyl ether results in increased expression of UQCRC1 protein CTD PMID:24090815 NCBI chr 8:109,589,735...109,601,481
Ensembl chr 8:109,589,706...109,601,480 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19765
    role 19738
      chemical role 19377
        fuel additive 3170
          tert-butyl ethyl ether 32
Path 2
Term Annotations click to browse term
  CHEBI ontology 19765
    subatomic particle 19763
      composite particle 19763
        hadron 19763
          baryon 19763
            nucleon 19763
              atomic nucleus 19763
                atom 19763
                  main group element atom 19712
                    p-block element atom 19712
                      carbon group element atom 19658
                        carbon atom 19654
                          organic molecular entity 19654
                            heteroorganic entity 19411
                              organochalcogen compound 19200
                                organooxygen compound 19109
                                  ether 17141
                                    tert-butyl ethyl ether 32
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