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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:ethyl 2-hydroxy-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate
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Accession:CHEBI:141398 term browser browse the term
Definition:A member of the class of pyrazolopyrimidines that is pyrazophos in which the the thiophosphate group has been hydrolysed to the corresponding hydroxy group. The active fungicide of the profungicide pyrazophos.
Synonyms:related_synonym: 5-methyl-2-oxo-1,2-dihydro-pyrazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester;   Formula=C10H11N3O3;   InChI=1S/C10H11N3O3/c1-3-16-10(15)7-5-13-8(11-6(7)2)4-9(14)12-13/h4-5H,3H2,1-2H3,(H,12,14);   InChIKey=ZUAAVNLKGAEZDG-UHFFFAOYSA-N;   SMILES=C=1(C(=NC=2N(C1)N=C(C2)O)C)C(OCC)=O;   ethyl 5-methyl-2-oxo-1,2-dihydropyrazolo[1,5-a]pyrimidine-6-carboxylate
 xref: CAS:57615-05-1;   Reaxys:887640


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pyrazophos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO pyrazophos metabolite results in decreased activity of ACHE protein; pyrazophos results in decreased activity of ACHE protein CTD PMID:33844597 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Tp53 tumor protein p53 affects activity ISO pyrazophos metabolite affects the activity of TP53 protein CTD PMID:35435491 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19900
    role 19875
      application 19710
        pesticide 17879
          fungicide 13196
            ethyl 2-hydroxy-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate 2
              pyrazophos 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19900
    subatomic particle 19898
      composite particle 19898
        hadron 19898
          baryon 19898
            nucleon 19898
              atomic nucleus 19898
                atom 19898
                  main group element atom 19845
                    p-block element atom 19845
                      chalcogen 19593
                        oxygen atom 19566
                          oxygen molecular entity 19566
                            hydroxides 19365
                              organic hydroxy compound 18976
                                alcohol 15413
                                  primary alcohol 14271
                                    ethanols 8471
                                      ethanol 8470
                                        ethyl ester 3590
                                          ethyl 2-hydroxy-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate 2
                                            pyrazophos 2
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