Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   


The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

go back to main search page
Accession:CHEBI:141354 term browser browse the term
Definition:An isoquinolinol that is 5-hydroxyisoquinolin-1(2H)-one which has been substituted at positions 4 and 8 by phenyl and methoxy groups, respectively. Isolated from the fermentation of an endophytic fungus Penicillium sp. R22 in Nerium indicum. It displayed weak antibacterial activity.
Synonyms:exact_synonym: 8-methoxy-4-phenylisoquinoline-1,5-diol
 related_synonym: 5-hydroxy-8-methoxy-4-phenyl-2H-isoquinolin-1-one;   Formula=C16H13NO3;   InChI=1S/C16H13NO3/c1-20-13-8-7-12(18)14-11(9-17-16(19)15(13)14)10-5-3-2-4-6-10/h2-9,18H,1H3,(H,17,19);   InChIKey=ZOITXTLCKPXXHV-UHFFFAOYSA-N;   SMILES=COC=1C=CC(=C2C(=CNC(C12)=O)C3=CC=CC=C3)O
 xref: PMID:27910702;   PMID:29867466;   PMID:29941838

show annotations for term's descendants           Sort by:

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19860
    role 19832
      biological role 19830
        antimicrobial agent 18222
          antifungal agent 17135
            5-hydroxy-8-methoxy-4-phenylisoquinolin-1(2H)-one 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19860
    subatomic particle 19858
      composite particle 19858
        hadron 19858
          baryon 19858
            nucleon 19858
              atomic nucleus 19858
                atom 19858
                  main group element atom 19804
                    p-block element atom 19804
                      carbon group element atom 19745
                        carbon atom 19741
                          organic molecular entity 19741
                            organic molecule 19692
                              organic cyclic compound 19503
                                organic heterocyclic compound 18875
                                  organonitrogen heterocyclic compound 18156
                                    isoquinolines 533
                                      isoquinolinol 48
                                        5-hydroxy-8-methoxy-4-phenylisoquinolin-1(2H)-one 0
paths to the root