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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:altenusin
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Accession:CHEBI:141340 term browser browse the term
Definition:A carboxybiphenyl that is [biphenyl]-2-carboxylic acid which is substituted by a hydroxy group at positions 3, 4' and 5', methoxy group at position 5 and a methyl group at position 2'. It is a a metabolite isolated from Alternaria and several other fungal species.
Synonyms:exact_synonym: 3,4',5'-trihydroxy-5-methoxy-2'-methyl[biphenyl]-2-carboxylic acid
 related_synonym: 2,4',5'-trihydroxy-5-methoxy-2'-methyl-(1,1'-biphenyl)-2-carboxylic acid;   2-(4,5-dihydroxy-2-methylphenyl)-6-hydroxy-4-methoxybenzoic acid;   Formula=C15H14O6;   InChI=1S/C15H14O6/c1-7-3-11(16)12(17)6-9(7)10-4-8(21-2)5-13(18)14(10)15(19)20/h3-6,16-18H,1-2H3,(H,19,20);   InChIKey=ADPBTBPPIIKLEH-UHFFFAOYSA-N;   MS-341;   SMILES=CC1=CC(=C(C=C1C=2C=C(C=C(C2C(=O)O)O)OC)O)O;   alutenusin
 xref: CAS:31186-12-6;   KNApSAcK:C00023666
 xref_mesh: MESH:C095643
 xref: PMID:10470682;   PMID:18494522;   PMID:19835393;   PMID:22366718;   PMID:22967766;   PMID:24385360;   PMID:24689437;   PMID:27450949;   PMID:28067492;   PMID:28300771;   PMID:28739572;   Reaxys:2223336



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altenusin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Top2a DNA topoisomerase II alpha decreases activity ISO altenusin results in decreased activity of TOP2A protein CTD PMID:27682608 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874
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  CHEBI ontology 19740
    role 19713
      biological role 19711
        antimicrobial agent 17880
          antifungal agent 16287
            altenusin 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19740
    subatomic particle 19738
      composite particle 19738
        hadron 19738
          baryon 19738
            nucleon 19738
              atomic nucleus 19738
                atom 19738
                  main group element atom 19686
                    p-block element atom 19686
                      carbon group element atom 19631
                        carbon atom 19627
                          organic molecular entity 19627
                            organic group 18846
                              organic divalent group 18832
                                organodiyl group 18832
                                  carbonyl group 18798
                                    carbonyl compound 18798
                                      carboxylic acid 18518
                                        aromatic carboxylic acid 11801
                                          benzoic acids 11775
                                            carboxybiphenyl 105
                                              altenusin 1
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