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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:altenusin
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Accession:CHEBI:141340 term browser browse the term
Definition:A carboxybiphenyl that is [biphenyl]-2-carboxylic acid which is substituted by a hydroxy group at positions 3, 4' and 5', methoxy group at position 5 and a methyl group at position 2'. It is a a metabolite isolated from Alternaria and several other fungal species.
Synonyms:exact_synonym: 3,4',5'-trihydroxy-5-methoxy-2'-methyl[biphenyl]-2-carboxylic acid
 related_synonym: 2,4',5'-trihydroxy-5-methoxy-2'-methyl-(1,1'-biphenyl)-2-carboxylic acid;   2-(4,5-dihydroxy-2-methylphenyl)-6-hydroxy-4-methoxybenzoic acid;   Formula=C15H14O6;   InChI=1S/C15H14O6/c1-7-3-11(16)12(17)6-9(7)10-4-8(21-2)5-13(18)14(10)15(19)20/h3-6,16-18H,1-2H3,(H,19,20);   InChIKey=ADPBTBPPIIKLEH-UHFFFAOYSA-N;   MS-341;   SMILES=CC1=CC(=C(C=C1C=2C=C(C=C(C2C(=O)O)O)OC)O)O;   alutenusin
 xref: CAS:31186-12-6;   KNApSAcK:C00023666
 xref_mesh: MESH:C095643
 xref: PMID:10470682;   PMID:18494522;   PMID:19835393;   PMID:22366718;   PMID:22967766;   PMID:24385360;   PMID:24689437;   PMID:27450949;   PMID:28067492;   PMID:28300771;   PMID:28739572;   Reaxys:2223336


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altenusin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Top2a DNA topoisomerase II alpha decreases activity ISO altenusin results in decreased activity of TOP2A protein CTD PMID:27682608 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
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Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      biological role 19848
        antimicrobial agent 18250
          antifungal agent 17164
            altenusin 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      carbon group element atom 19757
                        carbon atom 19754
                          organic molecular entity 19754
                            heteroorganic entity 19512
                              organochalcogen compound 19275
                                organooxygen compound 19191
                                  carbon oxoacid 18658
                                    carboxylic acid 18655
                                      aromatic carboxylic acid 12689
                                        benzoic acids 12666
                                          carboxybiphenyl 124
                                            altenusin 1
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