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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:1-(1-methylindol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea
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Accession:CHEBI:140936 term browser browse the term
Definition:A member of ther class of ureas that is urea in which a hydrogen attached to one of the nitrogens has been replaced by an N-methylindol-5-yl group, while a hydrogen attached to the other nitrogen has been replaced by a 3-methyl-1,2-thiazol-5-yl group. It is a potent and selective antagonist for the 5-hydroxytryptamine 2B (5-HT2B) receptor.
Synonyms:exact_synonym: 1-(1-methyl-1H-indol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea
 related_synonym: Formula=C14H14N4OS;   InChI=1S/C14H14N4OS/c1-9-7-13(20-17-9)16-14(19)15-11-3-4-12-10(8-11)5-6-18(12)2/h3-8H,1-2H3,(H2,15,16,19);   InChIKey=USFUFHFQWXDVMH-UHFFFAOYSA-N;   N-(1-methyl-1H-5-indolyl)-N'-(3-methyl-5-isothiazolyl)urea;   N-(1-methyl-5-indolyl)-N'-(3-methyl-5-isothiazolyl)urea;   SB-204741;   SB204741;   SMILES=S1N=C(C=C1NC(=O)NC2=CC3=C(N(C=C3)C)C=C2)C
 xref: CAS:152239-46-8;   PMID:10821800;   PMID:20374255;   PMID:20472767;   PMID:20969855;   PMID:21860590;   PMID:22120177;   PMID:22210189;   PMID:23769718;   PMID:25544272;   PMID:25667920;   PMID:26293029;   PMID:27511837;   PMID:29649585;   PMID:7582481;   PMID:7699699;   Wikipedia:SB-204741



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  CHEBI ontology 20050
    role 20001
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              1-(1-methylindol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea 0
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  CHEBI ontology 20050
    subatomic particle 20048
      composite particle 20048
        hadron 20048
          baryon 20048
            nucleon 20048
              atomic nucleus 20048
                atom 20048
                  main group element atom 19948
                    p-block element atom 19948
                      carbon group element atom 19872
                        carbon atom 19863
                          organic molecular entity 19863
                            organic group 18937
                              organic divalent group 18922
                                organodiyl group 18922
                                  carbonyl group 18872
                                    carbonyl compound 18872
                                      carboxylic acid 18556
                                        carboacyl group 17655
                                          univalent carboacyl group 17655
                                            carbamoyl group 17490
                                              carboxamide 17490
                                                monocarboxylic acid amide 15058
                                                  urea 5127
                                                    ureas 5124
                                                      1-(1-methylindol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea 0
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