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ONTOLOGY REPORT - ANNOTATIONS


Term:N-\{2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethyl\}-N-propylpropan-1-amine hydrochloride
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Accession:CHEBI:140905 term browser browse the term
Definition:An aromatic ether that is (2-phenoxyethyl)benzene which carries a 2-(dipropylamino)ethyl group at position 3 and a methoxy group at position 6. It is a potent and selective sigma1 receptor antagonist.
Synonyms:related_synonym: 4-methoxy-3-(2-phenylethoxy)-N,N-dipropyl-benzeneethanamine hydrochloride;   Formula=C23H34ClNO2;   InChI=1S/C23H33NO2.ClH/c1-4-15-24(16-5-2)17-13-21-11-12-22(25-3)23(19-21)26-18-14-20-9-7-6-8-10-20;/h6-12,19H,4-5,13-18H2,1-3H3;1H;   InChIKey=ZHGMDXSHODHWHV-UHFFFAOYSA-N;   N,N-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride;   N,N-dipropyl-2-[4-methoxy-3-(2-phenylethoxyl)phenyl]ethylamine hydrochloride;   NE-100;   SMILES=O(C=1C=C(CCN(CCC)CCC)C=CC1OC)CCC2=CC=CC=C2.[H]Cl
 xref: CAS:149409-57-4 "ChemIDplus";   CAS:149409-57-4 "SUBMITTER"
 xref_mesh: MESH:C083832
 xref: PMID:10090790 "SUBMITTER";   PMID:17556637 "Europe PMC";   PMID:27208832 "Europe PMC";   PMID:7475936 "Europe PMC";   PMID:7603628 "Europe PMC";   PMID:7609777 "Europe PMC";   PMID:7821367 "Europe PMC";   PMID:7823755 "Europe PMC";   PMID:7901723 "Europe PMC";   PMID:8041225 "Europe PMC";   PMID:8137864 "Europe PMC";   PMID:9544798 "Europe PMC";   Patent:EP0717990;   Patent:US5495046;   Reaxys:8296389 "Reaxys"


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N-\{2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethyl\}-N-propylpropan-1-amine hydrochloride term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sigmar1 sigma non-opioid intracellular receptor 1 JBrowse link 5 58,121,824 58,124,687 RGD:6480464

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Path 1
Term Annotations click to browse term
  CHEBI ontology 19764
    role 19711
      application 19361
        pharmaceutical 19230
          drug 19230
            receptor modulator 18589
              N-\{2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethyl\}-N-propylpropan-1-amine hydrochloride 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19764
    subatomic particle 19762
      composite particle 19762
        hadron 19762
          baryon 19762
            nucleon 19762
              atomic nucleus 19762
                atom 19762
                  main group element atom 19646
                    main group molecular entity 19646
                      s-block molecular entity 19408
                        hydrogen molecular entity 19397
                          hydrides 18356
                            inorganic hydride 17210
                              pnictogen hydride 17174
                                nitrogen hydride 17008
                                  azane 16701
                                    ammonia 16698
                                      organic amino compound 16697
                                        tertiary amino compound 8578
                                          N-\{2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethyl\}-N-propylpropan-1-amine hydrochloride 1
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