Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:antalarmin
go back to main search page
Accession:CHEBI:139557 term browser browse the term
Definition:A pyrrolopyrimidine that is 7H-pyrrolo[2,3-d]pyrimidin-4-amine which is substituted by methyl groups at positions 2, 5, and 6, by a mesityl group at position 7, and in which the amino substituent at position 4 has been substituted by ethyl and butyl groups. It is an antagonist of corticotropin-releasing factor 1 (CRF-1) receptors (Ki = 1 nM).
Synonyms:exact_synonym: N-butyl-N-ethyl-7-mesityl-2,5,6-trimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
 related_synonym: Formula=C24H34N4;   InChI=1S/C24H34N4/c1-9-11-12-27(10-2)23-21-18(6)19(7)28(24(21)26-20(8)25-23)22-16(4)13-15(3)14-17(22)5/h13-14H,9-12H2,1-8H3;   InChIKey=IXPROWGEHNVJOY-UHFFFAOYSA-N;   SMILES=C12=C(N=C(N=C1N(C(=C2C)C)C=3C(=CC(=CC3C)C)C)C)N(CCCC)CC
 xref: CAS:157284-96-3 "ChemIDplus"
 xref_mesh: MESH:C103016
 xref: PMID:12097816 "Europe PMC";   PMID:15696320 "Europe PMC";   PMID:16820021 "Europe PMC";   PMID:17182090 "Europe PMC";   PMID:17397037 "Europe PMC";   PMID:17705061 "Europe PMC";   PMID:18423834 "Europe PMC";   PMID:18428980 "Europe PMC";   PMID:18830607 "Europe PMC";   PMID:19573565 "Europe PMC";   PMID:21203337 "Europe PMC";   PMID:23211705 "Europe PMC";   PMID:23796983 "Europe PMC";   PMID:24444675 "Europe PMC";   PMID:8940412 "Europe PMC";   PMID:9886810 "Europe PMC";   Wikipedia:Antalarmin


show annotations for term's descendants       view all columns           Sort by:
 
antalarmin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Crhr1 corticotropin releasing hormone receptor 1 JBrowse link 10 92,191,473 92,233,662 RGD:6480464
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 JBrowse link 8 62,798,317 62,809,848 RGD:6480464
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 JBrowse link 1 266,422,127 266,429,947 RGD:6480464
G Faah fatty acid amide hydrolase JBrowse link 5 134,852,899 134,872,095 RGD:6480464
G Star steroidogenic acute regulatory protein JBrowse link 16 71,036,204 71,040,847 RGD:6480464
G Sult2a1 sulfotransferase family 2A member 1 JBrowse link 1 76,558,721 76,614,315 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19662
    role 19606
      application 19232
        refrigerant 16992
          ammonia 16562
            organic amino compound 16561
              tertiary amino compound 8525
                antalarmin 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19662
    subatomic particle 19658
      composite particle 19658
        hadron 19658
          baryon 19658
            nucleon 19658
              atomic nucleus 19658
                atom 19658
                  main group element atom 19539
                    main group molecular entity 19539
                      s-block molecular entity 19322
                        hydrogen molecular entity 19312
                          hydrides 18241
                            inorganic hydride 17110
                              pnictogen hydride 17068
                                nitrogen hydride 16889
                                  azane 16565
                                    ammonia 16562
                                      organic amino compound 16561
                                        tertiary amino compound 8525
                                          antalarmin 6
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.