Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:isotopically modified compound
go back to main search page
Accession:CHEBI:139358 term browser browse the term
Definition:Any molecular entity in which the isotopic ratio of nuclides for at least one element deviates measurably from that occurring in nature. The term includes both isotopically substituted compounds (in which essentially all the molecules of the compound have only the indicated nuclide(s) at each designated position) and isotopically labeled compounds (a formal mixture of an isotopically unmodified compound with one or more analogous isotopically substituted compound(s).
Synonyms:related_synonym: isotopically modified compounds


show annotations for term's descendants           Sort by:
2-deoxy-2-((18)F)fluoro-D-glucose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC2A1 solute carrier family 2 member 1 multiple interactions
affects uptake		 ISO
EXP		 [MRK 003 results in decreased expression of SLC2A1 protein] which results in decreased uptake of Fluorodeoxyglucose F18
SLC2A1 mRNA affects the uptake of Fluorodeoxyglucose F18		 CTD PMID:16595493 PMID:20197467 NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893 		JBrowse link
Palmitic acid(d3) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator increases expression
multiple interactions		 EXP Palmitic acid increases expression of BAX mRNA in cardiomyocytes
ghrelin inhibits the reaction [Palmitic acid increases expression of BAX mRNA in cardiomyocytes]		 RGD PMID:32084395 PMID:32084395 RGD:242905211, RGD:242905211 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression
multiple interactions		 EXP Palmitic acid decreases expression of BCL2 mRNA in cardiomyocytes
ghrelin inhibits the reaction [Palmitic acid decreases expression of BCL2 mRNA in cardiomyocytes]		 RGD PMID:32084395 PMID:32084395 RGD:242905211, RGD:242905211 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G IL1B interleukin 1 beta increases expression
multiple interactions		 EXP Palmitic acid increases expression of IL1b mRNA in cardiomyocytes
ghrelin inhibits the reaction [Palmitic acid increases expression of IL1b mRNA in cardiomyocytes]		 RGD PMID:32084395 PMID:32084395 RGD:242905211, RGD:242905211 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 increases expression
multiple interactions		 EXP Palmitic acid increases expression of IL6 mRNA in cardiomyocytes
ghrelin inhibits the reaction [Palmitic acid increases expression of IL6 mRNA in cardiomyocytes]		 RGD PMID:32084395 PMID:32084395 RGD:242905211, RGD:242905211 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G TGFB1 transforming growth factor beta 1 increases expression
multiple interactions		 EXP Palmitic acid increases expression of IL1b mRNA in cardiomyocytes
ghrelin inhibits the reaction [Palmitic acid increases expression of TGFB1 mRNA in cardiomyocytes] 		RGD PMID:32084395 PMID:32084395 RGD:242905211, RGD:242905211 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TNF tumor necrosis factor multiple interactions
increases expression 		EXP ghrelin inhibits the reaction [Palmitic acid increases expression of TNF mRNA in cardiomyocytes] RGD PMID:32084395 PMID:32084395 RGD:242905211, RGD:242905211 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26034
    chemical entity 26024
      molecular entity 25991
        isotopically modified compound 7
          ((18)O)water 0
          ((201)Tl)thallium monochloride 0
          (11)C-modified compound + 0
          (13)C-modified compound + 0
          (13)N-modified compound + 0
          (14)C-modified compound + 0
          (15)N-modified compound + 0
          (18)F radiopharmaceutical + 1
          (223)RaCl2 0
          chlormerodrin ((197)Hg) 0
          chlormerodrin ((203)Hg) 0
          deuterated compound + 6
          sodium 2-((125)I)iodohippurate 0
          sodium 2-((131)I)iodohippurate 0
          tritiated compound + 0
paths to the root