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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:isotopically modified compound
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Accession:CHEBI:139358 term browser browse the term
Definition:Any molecular entity in which the isotopic ratio of nuclides for at least one element deviates measurably from that occurring in nature. The term includes both isotopically substituted compounds (in which essentially all the molecules of the compound have only the indicated nuclide(s) at each designated position) and isotopically labeled compounds (a formal mixture of an isotopically unmodified compound with one or more analogous isotopically substituted compound(s).
Synonyms:related_synonym: isotopically modified compounds



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2-deoxy-2-((18)F)fluoro-D-glucose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc2a1 solute carrier family 2 member 1 multiple interactions
affects uptake
ISO [MRK 003 results in decreased expression of SLC2A1 protein] which results in decreased uptake of Fluorodeoxyglucose F18
SLC2A1 mRNA affects the uptake of Fluorodeoxyglucose F18
CTD PMID:16595493 PMID:20197467 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
Palmitic acid(d3) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO Palmitic acid increases expression of BAX mRNA in cardiomyocytes
ghrelin inhibits the reaction [Palmitic acid increases expression of BAX mRNA in cardiomyocytes]
RGD PMID:32084395 PMID:32084395 RGD:242905211, RGD:242905211 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO Palmitic acid decreases expression of BCL2 mRNA in cardiomyocytes
ghrelin inhibits the reaction [Palmitic acid decreases expression of BCL2 mRNA in cardiomyocytes]
RGD PMID:32084395 PMID:32084395 RGD:242905211, RGD:242905211 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
ISO Palmitic acid increases expression of IL1b mRNA in cardiomyocytes
ghrelin inhibits the reaction [Palmitic acid increases expression of IL1b mRNA in cardiomyocytes]
RGD PMID:32084395 PMID:32084395 RGD:242905211, RGD:242905211 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO Palmitic acid increases expression of IL6 mRNA in cardiomyocytes
ghrelin inhibits the reaction [Palmitic acid increases expression of IL6 mRNA in cardiomyocytes]
RGD PMID:32084395 PMID:32084395 RGD:242905211, RGD:242905211 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression
multiple interactions
ISO Palmitic acid increases expression of IL1b mRNA in cardiomyocytes
ghrelin inhibits the reaction [Palmitic acid increases expression of TGFB1 mRNA in cardiomyocytes]
RGD PMID:32084395 PMID:32084395 RGD:242905211, RGD:242905211 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO ghrelin inhibits the reaction [Palmitic acid increases expression of TNF mRNA in cardiomyocytes] RGD PMID:32084395 PMID:32084395 RGD:242905211, RGD:242905211 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    chemical entity 19916
      molecular entity 19916
        isotopically modified compound 7
          ((18)O)water 0
          ((201)Tl)thallium monochloride 0
          (11)C-modified compound + 0
          (13)C-modified compound + 0
          (13)N-modified compound + 0
          (14)C-modified compound + 0
          (15)N-modified compound + 0
          (18)F radiopharmaceutical + 1
          (223)RaCl2 0
          chlormerodrin ((197)Hg) 0
          chlormerodrin ((203)Hg) 0
          deuterated compound + 6
          sodium 2-((125)I)iodohippurate 0
          sodium 2-((131)I)iodohippurate 0
          tritiated compound + 0
paths to the root