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Term:N-(p-amylcinnamoyl)anthranilic acid
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Accession:CHEBI:139349 term browser browse the term
Definition:An amidobenzoic acid that is anthranilic acid in which one of the anilino hydrogens is replaced by a 4-pentylcinnamoyl group. It is a transient receptor potential (TRP) channel blocker and phospholipase A2 (PLA2) inhibitor.
Synonyms:exact_synonym: 2-{[(2E)-3-(4-pentylphenyl)prop-2-enoyl]amino}benzoic acid
 related_synonym: 4-amylcinnamoylanthranilic acid;   ACA;   Formula=C21H23NO3;   InChI=1S/C21H23NO3/c1-2-3-4-7-16-10-12-17(13-11-16)14-15-20(23)22-19-9-6-5-8-18(19)21(24)25/h5-6,8-15H,2-4,7H2,1H3,(H,22,23)(H,24,25)/b15-14+;   InChIKey=GAMRBCZMOOMBSQ-CCEZHUSRSA-N;   SMILES=O=C(O)C1=C(NC(=O)/C=C/C2=CC=C(C=C2)CCCCC)C=CC=C1;   p-amylcinnamoylanthranilic acid
 xref: CAS:110683-10-8
 xref_mesh: MESH:C085901
 xref: PMID:16604090;   PMID:17445088;   PMID:19382906;   PMID:20971070;   PMID:23566164;   PMID:26935063;   PMID:7932202;   Pubchem:329770958;   Reaxys:6521595;   Wikipedia:N-(p-amylcinnamoyl)anthranilic_acid

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N-(p-amylcinnamoyl)anthranilic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc13a2 solute carrier family 13 member 2 JBrowse link 10 65,664,665 65,692,046 RGD:6480464
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 JBrowse link 20 11,434,062 11,482,880 RGD:6480464

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Path 1
Term Annotations click to browse term
  CHEBI ontology 19778
    role 19725
      biological role 19724
        biophysical role 12287
          membrane transport modulator 12068
            TRP channel blocker 102
              N-(p-amylcinnamoyl)anthranilic acid 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19778
    subatomic particle 19776
      composite particle 19776
        hadron 19776
          baryon 19776
            nucleon 19776
              atomic nucleus 19776
                atom 19776
                  main group element atom 19662
                    p-block element atom 19662
                      carbon group element atom 19556
                        carbon atom 19545
                          organic molecular entity 19545
                            organic group 18459
                              organic divalent group 18453
                                organodiyl group 18453
                                  carbonyl group 18354
                                    carbonyl compound 18354
                                      carboxylic acid 18027
                                        carboacyl group 17185
                                          univalent carboacyl group 17185
                                            carbamoyl group 16923
                                              carboxamide 16923
                                                alpha,beta-unsaturated carboxylic acid amide 4764
                                                  enamide 4764
                                                    cinnamamides 1309
                                                      N-(p-amylcinnamoyl)anthranilic acid 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.