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Term:N-(p-amylcinnamoyl)anthranilic acid
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Accession:CHEBI:139349 term browser browse the term
Definition:An amidobenzoic acid that is anthranilic acid in which one of the anilino hydrogens is replaced by a 4-pentylcinnamoyl group. It is a transient receptor potential (TRP) channel blocker and phospholipase A2 (PLA2) inhibitor.
Synonyms:exact_synonym: 2-{[(2E)-3-(4-pentylphenyl)prop-2-enoyl]amino}benzoic acid
 related_synonym: 4-amylcinnamoylanthranilic acid;   ACA;   Formula=C21H23NO3;   InChI=1S/C21H23NO3/c1-2-3-4-7-16-10-12-17(13-11-16)14-15-20(23)22-19-9-6-5-8-18(19)21(24)25/h5-6,8-15H,2-4,7H2,1H3,(H,22,23)(H,24,25)/b15-14+;   InChIKey=GAMRBCZMOOMBSQ-CCEZHUSRSA-N;   SMILES=O=C(O)C1=C(NC(=O)/C=C/C2=CC=C(C=C2)CCCCC)C=CC=C1;   p-amylcinnamoylanthranilic acid
 xref: CAS:110683-10-8 "ChemIDplus"
 xref_mesh: MESH:C085901
 xref: PMID:16604090 "Europe PMC";   PMID:17445088 "Europe PMC";   PMID:19382906 "Europe PMC";   PMID:20971070 "Europe PMC";   PMID:23566164 "Europe PMC";   PMID:26935063 "Europe PMC";   PMID:7932202 "Europe PMC";   Pubchem:329770958 "SUBMITTER";   Reaxys:6521595 "Reaxys";   Wikipedia:N-(p-amylcinnamoyl)anthranilic_acid

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N-(p-amylcinnamoyl)anthranilic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc13a2 solute carrier family 13 member 2 JBrowse link 10 65,664,665 65,692,046 RGD:6480464
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 JBrowse link 20 11,434,062 11,482,880 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      biological role 19661
        biophysical role 12133
          membrane transport modulator 11897
            TRP channel blocker 102
              N-(p-amylcinnamoyl)anthranilic acid 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    p-block element atom 19598
                      carbon group element atom 19486
                        carbon atom 19480
                          organic molecular entity 19480
                            organic group 18407
                              organic divalent group 18397
                                organodiyl group 18397
                                  carbonyl group 18285
                                    carbonyl compound 18285
                                      carboxylic acid 17940
                                        carboacyl group 16948
                                          univalent carboacyl group 16948
                                            carbamoyl group 16630
                                              carboxamide 16630
                                                alpha,beta-unsaturated carboxylic acid amide 4761
                                                  enamide 4761
                                                    cinnamamides 1306
                                                      N-(p-amylcinnamoyl)anthranilic acid 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.