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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:139347 term browser browse the term
Definition:A retinoid that is all-trans-retinal carrying an oxo substituent at position 4 on the cyclohexenyl ring.
Synonyms:exact_synonym: (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-3-oxocyclohex-1-en-1-yl)nona-2,4,6,8-tetraenal
 related_synonym: 4-Oxoretinaldehyde;   4-ketoretinal;   4-oxoretinal;   Formula=C20H26O2;   InChI=1S/C20H26O2/c1-15(7-6-8-16(2)12-14-21)9-10-18-17(3)19(22)11-13-20(18,4)5/h6-10,12,14H,11,13H2,1-5H3/b8-6+,10-9+,15-7+,16-12+;   InChIKey=PLILDISEFZJECC-RMWYGNQTSA-N;   SMILES=C1(C)(C)C(\\C=C\\C(=C\\C=C\\C(=C\\C(=O)[H])\\C)\\C)=C(C)C(CC1)=O;   all-trans-4-ketoretinal;   all-trans-4-oxo-retinal
 xref: CAS:33532-44-4
 xref_mesh: MESH:C099660
 xref: PMID:10415093;   PMID:12528465;   PMID:15369820;   PMID:1775535;   PMID:17943179;   PMID:8643496;   Reaxys:2508352

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all-trans-4-oxoretinal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b1 aldo-keto reductase family 1 member B1 increases reduction ISO AKR1B1 protein results in increased reduction of 4-oxoretinaldehyde CTD PMID:19014918 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases reduction ISO AKR1B10 protein results in increased reduction of 4-oxoretinaldehyde CTD PMID:19014918 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19818
    role 19790
      biological role 19788
        inhibitor 18807
          gap junctional intercellular communication inhibitor 33
            all-trans-retinal 33
              all-trans-4-oxoretinal 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19818
    subatomic particle 19816
      composite particle 19816
        hadron 19816
          baryon 19816
            nucleon 19816
              atomic nucleus 19816
                atom 19816
                  main group element atom 19761
                    p-block element atom 19761
                      carbon group element atom 19703
                        carbon atom 19698
                          organic molecular entity 19698
                            organic group 18905
                              organic divalent group 18887
                                organodiyl group 18887
                                  carbonyl group 18853
                                    carbonyl compound 18853
                                      carboxylic acid 18569
                                        carboacyl group 17687
                                          univalent carboacyl group 17687
                                            formyl group 8841
                                              aldehyde 8841
                                                alpha,beta-unsaturated aldehyde 2913
                                                  enal 2913
                                                    retinal 41
                                                      all-trans-retinal 33
                                                        all-trans-4-oxoretinal 2
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