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ONTOLOGY REPORT - ANNOTATIONS


Term:carbocyclic thromboxane A2
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Accession:CHEBI:139043 term browser browse the term
Definition:A member of the class of thromboxanes that is thromboxane A2 in which the bridging oxygen has been replaced by a methylene group.
Synonyms:exact_synonym: (5Z)-7-{(1R,3R,4S,5R)-3-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[3.1.1]heptan-4-yl}hept-5-enoic acid
 related_synonym: 9alpha,11alpha-methylene thromboxane A2;   9alpha,11alpha-methylene-TXA2;   Formula=C21H34O4;   InChI=1S/C21H34O4/c1-2-3-6-9-17(22)12-13-20-19(16-14-18(15-16)25-20)10-7-4-5-8-11-21(23)24/h4,7,12-13,16-20,22H,2-3,5-6,8-11,14-15H2,1H3,(H,23,24)/b7-4-,13-12+/t16-,17-,18+,19-,20+/m0/s1;   InChIKey=VQUUFWNZZIMDBR-SXNJQZKASA-N;   SMILES=C1[C@H]2[C@@H]([C@H](O[C@@H]1C2)/C=C/[C@H](CCCCC)O)C/C=C\\CCCC(=O)O;   carbocyclic TXA2
 xref_mesh: MESH:C024587
 xref: PMID:10542977 "Europe PMC";   PMID:11483590 "Europe PMC";   PMID:12614148 "Europe PMC";   PMID:12628222 "Europe PMC";   PMID:1561230 "Europe PMC";   PMID:15789615 "Europe PMC";   PMID:16093422 "Europe PMC";   PMID:16896186 "Europe PMC";   PMID:17109692 "Europe PMC";   PMID:1838696 "Europe PMC";   PMID:3387452 "Europe PMC";   PMID:3512276 "Europe PMC";   PMID:6754126 "Europe PMC";   PMID:6960809 "Europe PMC";   PMID:7591017 "Europe PMC";   PMID:7693541 "Europe PMC";   PMID:7966472 "Europe PMC";   PMID:8135127 "Europe PMC";   PMID:8831114 "Europe PMC";   PMID:9014151 "Europe PMC";   PMID:9342927 "Europe PMC"
 cyclic_relationship: is_conjugate_acid_of CHEBI:138322


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carbocyclic thromboxane A2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tnfrsf11b TNF receptor superfamily member 11B JBrowse link 7 93,798,580 93,826,586 RGD:6480464
G Tnfsf11 TNF superfamily member 11 JBrowse link 15 60,482,527 60,512,704 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19654
    role 19598
      biological role 19596
        pharmacological role 18671
          agonist 17994
            thromboxane A2 agonist 2
              carbocyclic thromboxane A2 2
                18-hydroxycarbocyclic thromboxane A2 0
                19-hydroxycarbocyclic thromboxane A2 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    p-block element atom 19531
                      carbon group element atom 19413
                        carbon atom 19405
                          organic molecular entity 19405
                            organic group 18331
                              organic divalent group 18321
                                organodiyl group 18321
                                  carbonyl group 18209
                                    carbonyl compound 18209
                                      carboxylic acid 17908
                                        monocarboxylic acid 17245
                                          fatty acid 15807
                                            fatty acid derivative 1008
                                              icosanoid 450
                                                prostanoid 393
                                                  thromboxane 14
                                                    thromboxanes A 7
                                                      thromboxane A2 7
                                                        carbocyclic thromboxane A2 2
                                                          18-hydroxycarbocyclic thromboxane A2 0
                                                          19-hydroxycarbocyclic thromboxane A2 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.