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ONTOLOGY REPORT - ANNOTATIONS


Term:hydroxysafflor yellow A
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Accession:CHEBI:139030 term browser browse the term
Definition:A C-glycosyl compound that is 3,4,5-trihydroxycyclohexa-2,5-dien-1-one which is substituted by beta-D-glucosyl groups at positions 2 and 4, and by a p-hydroxycinnamoyl group at position 6. It is the main bioactive compound of a traditional Chinese medicine obtained from safflower (Carthamus tinctorius).
Synonyms:related_synonym: 2,4-di-beta-D-glucopyranosyl-3,4,5-trihydroxy-6-[(2E)-3-(4-hydroxyphenyl-1-oxo-2-propen-1-yl)]-2,5-cyclohexadien-1-one;   2,4-di-beta-D-glucopyranosyl-3,4,5-trihydroxy-6-[(2E)-3-(4-hydroxyphenyl-1-oxo-prop-2-en-1-yl)]cyclohexa-2,5-dien-1-one;   Formula=C27H32O16;   HSYA;   InChI=1S/C27H32O16/c28-7-12-16(32)19(35)21(37)23(42-12)15-18(34)14(11(31)6-3-9-1-4-10(30)5-2-9)24(39)27(41,25(15)40)26-22(38)20(36)17(33)13(8-29)43-26/h1-6,12-13,16-17,19-23,26,28-30,32-33,35-41H,7-8H2/b6-3+/t12-,13-,16-,17-,19+,20+,21-,22-,23+,26-,27?/m1/s1;   InChIKey=LIPJRCGLQNIXGO-ONZBGLOFSA-N;   SMILES=O1[C@H]([C@H](O)[C@@H](O)[C@H](O)[C@H]1CO)C2=C(O)C(C(O)=C(C2=O)C(=O)/C=C/C3=CC=C(O)C=C3)(O)[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)CO;   safflomin A
 xref: CAS:78281-02-4 "ChemIDplus";   FooDB:FDB020474;   HMDB:HMDB0040677
 xref_mesh: MESH:C085278
 xref: PMID:25626885 "Europe PMC";   PMID:26607471 "Europe PMC";   PMID:26754542 "Europe PMC";   PMID:26777519 "Europe PMC";   PMID:27063983 "Europe PMC";   PMID:27086971 "Europe PMC";   PMID:27176815 "Europe PMC";   PMID:27457091 "Europe PMC";   PMID:27599591 "Europe PMC";   PMID:27713966 "Europe PMC";   PMID:27731393 "Europe PMC";   PMID:27894114 "Europe PMC";   PMID:27909717 "Europe PMC";   PMID:28068632 "Europe PMC";   PMID:28074914 "Europe PMC";   PMID:28097465 "Europe PMC";   PMID:28122306 "Europe PMC";   PMID:28154251 "Europe PMC";   PMID:28191279 "Europe PMC";   PMID:28264629 "Europe PMC";   PMID:28468657 "Europe PMC";   PMID:28553231 "Europe PMC";   PMID:28840700 "Europe PMC";   PMID:28932195 "Europe PMC";   PMID:28966242 "Europe PMC";   PMID:29076598 "Europe PMC";   PMID:29107614 "Europe PMC";   PMID:29107696 "Europe PMC";   Reaxys:8669627 "Reaxys"


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hydroxysafflor yellow A term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd40 CD40 molecule JBrowse link 3 161,519,789 161,534,943 RGD:6480464
G Cd40lg CD40 ligand JBrowse link X 159,703,703 159,714,886 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Itgb3 integrin subunit beta 3 JBrowse link 10 92,667,869 92,783,413 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:6480464
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:6480464
G Prkaca protein kinase cAMP-activated catalytic subunit alpha JBrowse link 19 25,095,089 25,118,869 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Vcam1 vascular cell adhesion molecule 1 JBrowse link 2 219,071,193 219,090,931 RGD:6480464

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Path 1
Term Annotations click to browse term
  CHEBI ontology 19612
    role 19555
      chemical role 19050
        antioxidant 13675
          hydroxysafflor yellow A 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 19612
    subatomic particle 19608
      composite particle 19608
        hadron 19608
          baryon 19608
            nucleon 19608
              atomic nucleus 19608
                atom 19608
                  main group element atom 19487
                    p-block element atom 19487
                      carbon group element atom 19361
                        carbon atom 19353
                          organic molecular entity 19353
                            heteroorganic entity 18924
                              organochalcogen compound 18673
                                organooxygen compound 18581
                                  carbohydrates and carbohydrate derivatives 11696
                                    carbohydrate 11696
                                      carbohydrate derivative 11308
                                        glycosyl compound 10289
                                          C-glycosyl compound 221
                                            hydroxysafflor yellow A 10
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