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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:3,4-dihydroxyphenylethyleneglycol
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Accession:CHEBI:1387 term browser browse the term
Definition:A tetrol composed of ethyleneglycol having a 3,4-dihydroxyphenyl group at the 1-position.
Synonyms:exact_synonym: 4-(1,2-dihydroxyethyl)benzene-1,2-diol
 related_synonym: (3,4-dihydroxyphenyl)ethylene glycol;   1-(3,4-dihydroxyphenyl)-1,2-ethanediol;   2-hydroxy-2-(3,4-dihydroxy)phenylethanol;   3,4-Dihydroxyphenylglycol;   3,4-dihydroxyphenethyl glycol;   3,4-dihydroxyphenylethyl glycol;   DHPG;   DOPEG;   Dihydroxyphenylethylene glycol;   Formula=C8H10O4;   InChI=1S/C8H10O4/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8-12H,4H2;   InChIKey=MTVWFVDWRVYDOR-UHFFFAOYSA-N;   SMILES=OCC(O)c1ccc(O)c(O)c1;   beta,3,4-trihydroxy phenethyl alcohol
 xref: CAS:3343-19-9;   HMDB:HMDB0000318;   KEGG:C05576
 xref_mesh: MESH:C010117
 xref: MetaCyc:CPD-11878;   PMID:11479664;   PMID:16218695;   PMID:16819902;   PMID:22770225;   PMID:2468969;   PMID:2645784;   PMID:2907005;   PMID:3161030;   PMID:4091997;   PMID:6146669;   PMID:6497782;   PMID:6671452;   PMID:6875564;   PMID:7176821;   Reaxys:2210995


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3,4-dihydroxyphenylethyleneglycol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase increases methylation ISO COMT protein results in increased methylation of 3,4-dihydroxyphenylglycol CTD PMID:11160877 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Mgll monoglyceride lipase affects response to substance ISO MGLL protein affects the susceptibility to 3,4-dihydroxyphenylglycol CTD PMID:21911610 NCBI chr 4:121,192,187...121,294,187
Ensembl chr 4:121,192,195...121,294,179 		JBrowse link
G Plcb1 phospholipase C beta 1 multiple interactions
increases activity		 EXP [3,4-dihydroxyphenylglycol co-treated with Guanosine 5'-O-(3-Thiotriphosphate)] results in increased activity of PLCB1 protein; Caffeine inhibits the reaction [3,4-dihydroxyphenylglycol results in increased activity of PLCB1 protein]; Caffeine inhibits the reaction [[3,4-dihydroxyphenylglycol co-treated with Guanosine 5'-O-(3-Thiotriphosphate)] results in increased activity of PLCB1 protein]; Theophylline inhibits the reaction [3,4-dihydroxyphenylglycol results in increased activity of PLCB1 protein]; Theophylline inhibits the reaction [[3,4-dihydroxyphenylglycol co-treated with Guanosine 5'-O-(3-Thiotriphosphate)] results in increased activity of PLCB1 protein] CTD PMID:15998294 NCBI chr 3:122,059,968...122,772,896
Ensembl chr 3:122,060,031...122,772,869 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19784
      biological role 19782
        biochemical role 19495
          metabolite 19480
            3,4-dihydroxyphenylethyleneglycol 3
              (R)-3,4-dihydroxyphenylethyleneglycol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19810
      composite particle 19810
        hadron 19810
          baryon 19810
            nucleon 19810
              atomic nucleus 19810
                atom 19810
                  main group element atom 19755
                    p-block element atom 19755
                      carbon group element atom 19698
                        carbon atom 19693
                          organic molecular entity 19693
                            organic molecule 19651
                              organic cyclic compound 19457
                                organic aromatic compound 19315
                                  phenols 18635
                                    benzenediols 9102
                                      catechols 3353
                                        3,4-dihydroxyphenylethyleneglycol 3
                                          (R)-3,4-dihydroxyphenylethyleneglycol 0
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