The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
An organic heteropentacyclic compound and ent-kaurane diterpenoid with formula C20H28O6 isolated from the leaves of the medicinal herb Rabdosia rubescens.
oridonin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of BAX mRNA]; oridonin inhibits the reaction [Kainic Acid results in increased expression of BAX mRNA]
oridonin analog results in decreased expression of BCL2 protein; oridonin results in decreased expression of BCL2 protein oridonin inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of BCL2 mRNA]; oridonin inhibits the reaction [Kainic Acid results in decreased expression of BCL2 mRNA]
oridonin results in increased cleavage of CASP3 protein oridonin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased activity of CASP3 protein]; oridonin inhibits the reaction [Kainic Acid results in increased activity of CASP3 protein]
oridonin inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased activity of CAT protein]; oridonin inhibits the reaction [Kainic Acid results in decreased activity of CAT protein]
oridonin inhibits the reaction [TGFB1 protein results in increased expression of CDH1 mRNA]; oridonin inhibits the reaction [TGFB1 protein results in increased expression of CDH1 protein] oridonin results in increased expression of CDH1 mRNA; oridonin results in increased expression of CDH1 protein
oridonin results in decreased expression of CDH2 mRNA; oridonin results in decreased expression of CDH2 protein oridonin inhibits the reaction [TGFB1 protein results in decreased expression of CDH2 mRNA]; oridonin inhibits the reaction [TGFB1 protein results in decreased expression of CDH2 protein]
oridonin analog inhibits the reaction [EGF protein promotes the reaction [EGFR protein modified form binds to STAT3 protein]]; oridonin analog inhibits the reaction [EGF protein promotes the reaction [SRC protein modified form binds to STAT3 protein]]; oridonin analog inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein]
oridonin analog inhibits the reaction [EGF protein promotes the reaction [EGFR protein modified form binds to STAT3 protein]]; oridonin analog inhibits the reaction [EGFR protein results in increased phosphorylation of STAT3 protein]
oridonin inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased activity of GSR protein]; oridonin inhibits the reaction [Kainic Acid results in decreased activity of GSR protein]
oridonin results in increased expression of and results in increased activity of HMOX1 protein oridonin results in increased expression of HMOX1 mRNA; oridonin results in increased expression of HMOX1 protein
oridonin results in decreased expression of IFNG protein oridonin analog inhibits the reaction [IFNG protein results in increased phosphorylation of STAT3 protein]
oridonin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of IL1B protein]; oridonin inhibits the reaction [Kainic Acid results in increased expression of IL1B protein]
oridonin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of IL6 protein]; oridonin inhibits the reaction [Kainic Acid results in increased expression of IL6 protein] oridonin analog inhibits the reaction [IL6 protein affects the localization of STAT3 protein]; oridonin analog inhibits the reaction [IL6 protein promotes the reaction [JAK1 protein modified form binds to STAT3 protein]]; oridonin analog inhibits the reaction [IL6 protein promotes the reaction [STAT1 protein binds to STAT3 protein]]; oridonin analog inhibits the reaction [IL6 protein promotes the reaction [STAT3 protein binds to STAT3 protein]]; oridonin analog inhibits the reaction [IL6 protein results in increased expression of STAT3 mRNA]; oridonin analog inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]
oridonin analog inhibits the reaction [IL6 protein promotes the reaction [JAK1 protein modified form binds to STAT3 protein]]; oridonin analog inhibits the reaction [JAK1 protein results in increased phosphorylation of STAT3 protein]
oridonin results in increased cleavage of PARP1 protein oridonin analog results in decreased expression of and results in increased cleavage of PARP1 protein
oridonin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of PTGS2 protein]; oridonin inhibits the reaction [Kainic Acid results in increased expression of PTGS2 protein]
oridonin results in decreased expression of SNAI1 mRNA; oridonin results in decreased expression of SNAI1 protein oridonin inhibits the reaction [TGFB1 protein results in decreased expression of SNAI1 mRNA]; oridonin inhibits the reaction [TGFB1 protein results in decreased expression of SNAI1 protein]
oridonin inhibits the reaction [TGFB1 protein results in decreased expression of SNAI2 mRNA]; oridonin inhibits the reaction [TGFB1 protein results in decreased expression of SNAI2 protein] oridonin results in decreased expression of SNAI2 mRNA; oridonin results in decreased expression of SNAI2 protein
oridonin analog inhibits the reaction [EGF protein promotes the reaction [SRC protein modified form binds to STAT3 protein]]; oridonin analog inhibits the reaction [SRC protein results in increased phosphorylation of STAT3 protein]
oridonin analog inhibits the reaction [IFNG protein results in increased phosphorylation of STAT3 protein] oridonin analog binds to and results in decreased stability of STAT3 protein; oridonin analog inhibits the reaction [EGF protein promotes the reaction [EGFR protein modified form binds to STAT3 protein]]; oridonin analog inhibits the reaction [EGF protein promotes the reaction [SRC protein modified form binds to STAT3 protein]]; oridonin analog inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein]; oridonin analog inhibits the reaction [EGFR protein results in increased phosphorylation of STAT3 protein]; oridonin analog inhibits the reaction [IFNG protein results in increased phosphorylation of STAT3 protein]; oridonin analog inhibits the reaction [IL6 protein affects the localization of STAT3 protein]; oridonin analog inhibits the reaction [IL6 protein promotes the reaction [JAK1 protein modified form binds to STAT3 protein]]; oridonin analog inhibits the reaction [IL6 protein promotes the reaction [STAT1 protein binds to STAT3 protein]]; oridonin analog inhibits the reaction [IL6 protein promotes the reaction [STAT3 protein binds to STAT3 protein]]; oridonin analog inhibits the reaction [IL6 protein results in increased expression of STAT3 mRNA]; oridonin analog inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]; oridonin analog inhibits the reaction [JAK1 protein results in increased phosphorylation of STAT3 protein]; oridonin analog inhibits the reaction [SRC protein results in increased phosphorylation of STAT3 protein] oridonin analog results in decreased phosphorylation of STAT3 protein
oridonin results in increased expression of TGFB1 protein oridonin inhibits the reaction [TGFB1 protein results in decreased expression of CDH2 mRNA]; oridonin inhibits the reaction [TGFB1 protein results in decreased expression of CDH2 protein]; oridonin inhibits the reaction [TGFB1 protein results in decreased expression of SNAI1 mRNA]; oridonin inhibits the reaction [TGFB1 protein results in decreased expression of SNAI1 protein]; oridonin inhibits the reaction [TGFB1 protein results in decreased expression of SNAI2 mRNA]; oridonin inhibits the reaction [TGFB1 protein results in decreased expression of SNAI2 protein]; oridonin inhibits the reaction [TGFB1 protein results in decreased expression of VIM mRNA]; oridonin inhibits the reaction [TGFB1 protein results in decreased expression of VIM protein]; oridonin inhibits the reaction [TGFB1 protein results in increased expression of CDH1 mRNA]; oridonin inhibits the reaction [TGFB1 protein results in increased expression of CDH1 protein]; oridonin inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD2 protein]; oridonin inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]
oridonin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of TNF protein]; oridonin inhibits the reaction [Kainic Acid results in increased expression of TNF protein]
oridonin results in decreased expression of VIM mRNA; oridonin results in decreased expression of VIM protein oridonin inhibits the reaction [TGFB1 protein results in decreased expression of VIM mRNA]; oridonin inhibits the reaction [TGFB1 protein results in decreased expression of VIM protein]