CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: profungicide
Accession: CHEBI:136645
browse the term
Definition: A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active fungicide for which it is a profungicide.
Synonyms: related_synonym: pro-fungicide; pro-fungicides; profungicides
xref: PMID:11929539; PMID:25746994; PMID:26449612
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Als2
alsin Rho guanine nucleotide exchange factor ALS2
multiple interactions
ISO
methyldithiocarbamate affects the reaction [Lipopolysaccharides results in increased expression of ALS2 mRNA]
CTD
PMID:19339665
NCBI chr 9:60,613,182...60,686,394
Ensembl chr 9:60,613,167...60,670,737
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Cat
catalase
multiple interactions
ISO
methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of CAT mRNA]
CTD
PMID:19339665
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Ccl11
C-C motif chemokine ligand 11
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CCL11 protein]
CTD
PMID:24056979
NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
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Ccl2
C-C motif chemokine ligand 2
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CCL2 protein]
CTD
PMID:24056979
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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Ccl3
C-C motif chemokine ligand 3
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL3 protein]
CTD
PMID:19339665 PMID:24056979
NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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Ccl4
C-C motif chemokine ligand 4
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CCL4 protein]
CTD
PMID:24056979
NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
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Ccl5
C-C motif chemokine ligand 5
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CCL5 protein]
CTD
PMID:24056979
NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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Cd40
CD40 molecule
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of CD40 mRNA]
CTD
PMID:24056979
NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
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Cd55
CD55 molecule (Cromer blood group)
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in decreased expression of CD55 mRNA]
CTD
PMID:24056979
NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831
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Cfb
complement factor B
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of CFB mRNA]
CTD
PMID:24056979
NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
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Clec7a
C-type lectin domain containing 7A
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in decreased expression of CLEC7A mRNA]
CTD
PMID:24056979
NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897
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Crtam
cytotoxic and regulatory T cell molecule
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in decreased expression of CRTAM mRNA]
CTD
PMID:24056979
NCBI chr 8:41,340,117...41,377,381
Ensembl chr 8:41,340,837...41,377,343
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Csf2
colony stimulating factor 2
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of CSF2 mRNA]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of CSF2 protein]
CTD
PMID:19339665 PMID:24056979
NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
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Ctsb
cathepsin B
multiple interactions
ISO
methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of CTSB mRNA]
CTD
PMID:19339665
NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
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Cxcl9
C-X-C motif chemokine ligand 9
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of CXCL9 protein]; methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CXCL9 protein]
CTD
PMID:16321413 PMID:24056979
NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
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Dhx58
DEXH-box helicase 58
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of DHX58 mRNA]
CTD
PMID:24056979
NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525
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Eif2ak2
eukaryotic translation initiation factor 2-alpha kinase 2
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of EIF2AK2 mRNA]
CTD
PMID:24056979
NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971
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Ereg
epiregulin
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in decreased expression of EREG mRNA]
CTD
PMID:24056979
NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062
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Fcgr1a
Fc gamma receptor 1A
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of FCGR1 mRNA]
CTD
PMID:24056979
NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994
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Gab1
GRB2-associated binding protein 1
multiple interactions
ISO
methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of GAB1 mRNA]
CTD
PMID:19339665
NCBI chr19:27,131,262...27,239,236
Ensembl chr19:27,131,262...27,239,236
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Gclm
glutamate cysteine ligase, modifier subunit
multiple interactions
ISO
methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of GCLM mRNA]
CTD
PMID:19339665
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
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Gpx3
glutathione peroxidase 3
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of GPX3 mRNA]
CTD
PMID:19339665
NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
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Hif1a
hypoxia inducible factor 1 subunit alpha
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of HIF1A mRNA]
CTD
PMID:19339665
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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Idh1
isocitrate dehydrogenase (NADP(+)) 1
multiple interactions
ISO
methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of IDH1 mRNA]
CTD
PMID:19339665
NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708
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Ifih1
interferon induced with helicase C domain 1
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IFIH1 mRNA]
CTD
PMID:24056979
NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456
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Ifit2
interferon-induced protein with tetratricopeptide repeats 2
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IFIT2 mRNA]
CTD
PMID:24056979
NCBI chr 1:232,102,570...232,108,638
Ensembl chr 1:232,102,570...232,108,635
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Ifit3
interferon-induced protein with tetratricopeptide repeats 3
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IFIT3 mRNA]
CTD
PMID:24056979
NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307
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Ifnb1
interferon beta 1
multiple interactions
ISO
methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]
CTD
PMID:24056979
NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523
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Ifng
interferon gamma
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IFNG mRNA]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IFNG protein]
CTD
PMID:15933225 PMID:19339665
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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Il10
interleukin 10
multiple interactions
ISO
[Lipopolysaccharides co-treated with methyldithiocarbamate] results in increased expression of IL10 mRNA; [Lipopolysaccharides co-treated with methyldithiocarbamate] results in increased secretion of IL10 protein; [methyldithiocarbamate binds to Copper] promotes the reaction [Lipopolysaccharides results in increased secretion of IL10 protein]; [Nadolol co-treated with Mifepristone] promotes the reaction [methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased secretion of IL10 protein]]; Buthionine Sulfoximine promotes the reaction [methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased secretion of IL10 protein]]; methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA]; methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of IL10 protein]; methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased secretion of IL10 protein]
CTD
PMID:15933225 PMID:16321413 PMID:19339665 PMID:24056979
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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Il12a
interleukin 12A
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL12A mRNA]
CTD
PMID:15933225
NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
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Il12b
interleukin 12B
multiple interactions
ISO
[Nadolol co-treated with Mifepristone] inhibits the reaction [methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]]; Buthionine Sulfoximine inhibits the reaction [methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]
CTD
PMID:15933225 PMID:16321413 PMID:19339665 PMID:24056979
NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
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Il18
interleukin 18
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 mRNA]
CTD
PMID:15933225
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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Il1a
interleukin 1 alpha
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]
CTD
PMID:15933225
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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Il1b
interleukin 1 beta
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
CTD
PMID:15933225 PMID:19339665 PMID:24056979
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il6
interleukin 6
multiple interactions
ISO
Buthionine Sulfoximine inhibits the reaction [methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
CTD
PMID:19339665
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Irf3
interferon regulatory factor 3
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IRF3 mRNA]
CTD
PMID:24056979
NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935
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Irf4
interferon regulatory factor 4
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IRF4 mRNA]
CTD
PMID:24056979
NCBI chr17:33,721,800...33,742,570
Ensembl chr17:33,721,811...33,740,070
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Irf5
interferon regulatory factor 5
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IRF5 mRNA]
CTD
PMID:24056979
NCBI chr 4:58,127,577...58,140,665
Ensembl chr 4:58,127,640...58,139,267
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Irf7
interferon regulatory factor 7
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IRF7 mRNA]
CTD
PMID:24056979
NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
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Irgm
immunity-related GTPase M
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IRGM1 mRNA]
CTD
PMID:24056979
NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578
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Isg15
ISG15 ubiquitin-like modifier
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of ISG15 mRNA]
CTD
PMID:24056979
NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435
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Klrk1
killer cell lectin like receptor K1
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of KLRK1 mRNA]
CTD
PMID:24056979
NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459
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Malt1
MALT1 paracaspase
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MALT1 mRNA]
CTD
PMID:24056979
NCBI chr18:58,942,282...58,996,318
Ensembl chr18:58,942,299...58,994,260
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Mapk1
mitogen activated protein kinase 1
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]
CTD
PMID:15933225
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk14
mitogen activated protein kinase 14
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]
CTD
PMID:15933225
NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
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Mapk3
mitogen activated protein kinase 3
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]
CTD
PMID:15933225
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Mapk8
mitogen-activated protein kinase 8
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]
CTD
PMID:15933225
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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Masp1
MBL associated serine protease 1
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in decreased expression of MASP1 mRNA]
CTD
PMID:24056979
NCBI chr11:77,334,794...77,405,271
Ensembl chr11:77,334,859...77,402,974
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Mbl2
mannose binding lectin 2
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MBL2 mRNA]
CTD
PMID:24056979
NCBI chr 1:228,016,439...228,024,736
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Mif
macrophage migration inhibitory factor
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MIF mRNA]
CTD
PMID:15933225
NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
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Mnda
myeloid cell nuclear differentiation antigen
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IFI204 mRNA]
CTD
PMID:24056979
NCBI chr13:86,017,888...86,035,556
Ensembl chr13:86,017,892...86,034,201
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Mtf1
metal-regulatory transcription factor 1
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MTF1 mRNA]
CTD
PMID:19339665
NCBI chr 5:137,062,319...137,107,136
Ensembl chr 5:137,062,376...137,107,136
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Mx1
MX dynamin like GTPase 1
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MX1 mRNA]
CTD
PMID:24056979
NCBI chr11:36,799,659...36,825,209
Ensembl chr11:36,799,660...36,823,507
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Mx2
MX dynamin like GTPase 2
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MX2 mRNA]
CTD
PMID:24056979
NCBI chr11:36,905,698...36,936,308
Ensembl chr11:36,906,111...36,930,342
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Myd88
MYD88, innate immune signal transduction adaptor
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MYD88 mRNA]
CTD
PMID:24056979
NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
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Myo1f
myosin IF
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in decreased expression of MYO1F mRNA]
CTD
PMID:24056979
NCBI chr 7:14,363,340...14,413,911
Ensembl chr 7:14,363,350...14,413,911
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Nfkb1
nuclear factor kappa B subunit 1
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of NFKB1 mRNA]
CTD
PMID:24056979
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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Nod1
nucleotide-binding oligomerization domain containing 1
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of NOD1 mRNA]
CTD
PMID:24056979
NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404
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Ppp1r15b
protein phosphatase 1, regulatory subunit 15B
multiple interactions
ISO
methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of PPP1R15B mRNA]
CTD
PMID:19339665
NCBI chr13:44,577,840...44,585,737
Ensembl chr13:44,577,932...44,585,737
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Prdx1
peroxiredoxin 1
multiple interactions
ISO
methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of PRDX1 mRNA]
CTD
PMID:19339665
NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856
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Prnp
prion protein
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of PRNP mRNA]
CTD
PMID:19339665
NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
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Psmb5
proteasome 20S subunit beta 5
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of PSMB5 mRNA]
CTD
PMID:19339665
NCBI chr15:28,072,772...28,077,367
Ensembl chr15:28,072,781...28,077,440
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Rig1
RNA sensor RIG-1
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of RIGI mRNA]
CTD
PMID:24056979
NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:55,321,235...55,370,819
G
Ripk2
receptor-interacting serine-threonine kinase 2
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of RIPK2 mRNA]
CTD
PMID:24056979
NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657
G
Sod2
superoxide dismutase 2
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of SOD2 mRNA]
CTD
PMID:19339665
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
G
Srxn1
sulfiredoxin 1
multiple interactions
ISO
methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of SRXN1 mRNA]
CTD
PMID:19339665
NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
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Stat1
signal transducer and activator of transcription 1
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of STAT1 mRNA]
CTD
PMID:24056979
NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
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Stat5a
signal transducer and activator of transcription 5A
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of STAT5A mRNA]
CTD
PMID:24056979
NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866
G
Tirap
TIR domain containing adaptor protein
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of TIRAP mRNA]
CTD
PMID:24056979
NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432
G
Tlr3
toll-like receptor 3
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of TLR3 mRNA]
CTD
PMID:24056979
NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545
G
Tnf
tumor necrosis factor
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
CTD
PMID:19339665
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
G
Tor1aip2
torsin 1A interacting protein 2
multiple interactions
ISO
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of TOR1AIP2 mRNA]
CTD
PMID:24056979
NCBI chr13:68,225,226...68,256,536
Ensembl chr13:68,230,009...68,256,536 Ensembl chr13:68,230,009...68,256,536
G
Txnrd2
thioredoxin reductase 2
multiple interactions
ISO
methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of TXNRD2 mRNA]
CTD
PMID:19339665
NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156
G
Uba1
ubiquitin-like modifier activating enzyme 1
multiple interactions
ISO
methyldithiocarbamate results in increased activity of and results in increased ubiquitination of UBA1 protein
CTD
PMID:25714994
NCBI chr X:1,508,700...1,530,677
Ensembl chr X:1,508,666...1,530,636
G
Xpa
XPA, DNA damage recognition and repair factor
multiple interactions
ISO
methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of XPA mRNA]
CTD
PMID:19339665
NCBI chr 5:60,431,673...60,475,726
Ensembl chr 5:60,431,673...60,475,726
G
Ache
acetylcholinesterase
decreases activity
ISO
pyrazophos metabolite results in decreased activity of ACHE protein; pyrazophos results in decreased activity of ACHE protein
CTD
PMID:33844597
NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
G
Tp53
tumor protein p53
affects activity
ISO
pyrazophos metabolite affects the activity of TP53 protein
CTD
PMID:35435491
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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