CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: Theaflavin 3,3'-digallate
Accession: CHEBI:136608
browse the term
Synonyms: exact_synonym: (3,4,5-Trihydroxy-6-oxo-6H-benzo[7]annulene-1,8-diyl)bis[(2R,3R)-5,7-dihydroxy-3,4-dihydro-2H-chromene-2,3-diyl] bis(3,4,5-trihydroxybenzoate)
related_synonym: Formula=C43H32O20; InChI=1S/C43H32O20/c44-17-7-23(46)21-12-33(62-42(58)15-3-25(48)36(54)26(49)4-15)40(60-31(21)9-17)14-1-19-20(11-30(53)39(57)35(19)38(56)29(52)2-14)41-34(13-22-24(47)8-18(45)10-32(22)61-41)63-43(59)16-5-27(50)37(55)28(51)6-16/h1-11,33-34,40-41,44-51,53-55,57H,12-13H2,(H,52,56)/t33-,34-,40-,41-/m1/s1; InChIKey=ZEASWHWETFMWCV-ISBUVJFSSA-N; SMILES=O1[C@@H]([C@H](OC(=O)C2=CC(O)=C(O)C(O)=C2)CC=3C1=CC(O)=CC3O)C=4C5=CC([C@H]6OC=7C(C[C@H]6OC(=O)C8=CC(O)=C(O)C(O)=C8)=C(O)C=C(O)C7)=CC(=O)C(O)=C5C(O)=C(O)C4
xref: Chemspider:410681
xref_mesh: MESH:C585473
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1700017N19Rik
RIKEN cDNA 1700017N19 gene
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of C12ORF50 mRNA
CTD
PMID:34925699
NCBI chr10:100,426,346...100,454,257
Ensembl chr10:100,426,346...100,454,263
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4930590J08Rik
RIKEN cDNA 4930590J08 gene
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of C3ORF20 mRNA
CTD
PMID:34925699
NCBI chr 6:91,877,732...91,928,717
Ensembl chr 6:91,879,790...91,927,706
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AA986860
expressed sequence AA986860
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of C1ORF116 mRNA
CTD
PMID:34925699
NCBI chr 1:130,659,707...130,672,359
Ensembl chr 1:130,659,713...130,672,359
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Abcc2
ATP-binding cassette, sub-family member 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ABCC2 mRNA
CTD
PMID:34925699
NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
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Acadm
acyl-Coenzyme A dehydrogenase, medium chain
multiple interactions
EXP
theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of ACADM mRNA]
CTD
PMID:36105184
NCBI chr 3:153,627,990...153,650,280
Ensembl chr 3:153,627,994...153,650,269
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Acan
aggrecan
multiple interactions
ISO
theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of ACAN mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of ACAN protein]
CTD
PMID:35847580
NCBI chr 7:78,702,974...78,764,847
Ensembl chr 7:78,703,231...78,764,847
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Accsl
1-aminocyclopropane-1-carboxylate synthase (inactive)-like
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ACCSL mRNA
CTD
PMID:34925699
NCBI chr 2:93,685,705...93,760,827
Ensembl chr 2:93,685,706...93,760,827
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Ace2
angiotensin converting enzyme 2
affects binding
ISO
theaflavin-3,3'-digallate binds to ACE2 protein
CTD
PMID:34138966
NCBI chr X:162,922,338...162,971,414
Ensembl chr X:162,922,328...162,971,416
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Ache
acetylcholinesterase
multiple interactions
EXP
theaflavin-3,3'-digallate inhibits the reaction [Galactose results in increased activity of ACHE protein]
CTD
PMID:36638877
NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
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Acot6
acyl-CoA thioesterase 6
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ACOT6 mRNA
CTD
PMID:34925699
NCBI chr12:84,147,538...84,158,128
Ensembl chr12:84,147,428...84,158,123
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Acrbp
proacrosin binding protein
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ACRBP mRNA
CTD
PMID:34925699
NCBI chr 6:125,026,890...125,040,228
Ensembl chr 6:125,026,652...125,040,230
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Acta2
actin alpha 2, smooth muscle, aorta
multiple interactions
ISO
theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in decreased expression of ACTA2 protein]
CTD
PMID:35903325
NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990
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Actl6b
actin-like 6B
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ACTL6B mRNA
CTD
PMID:34925699
NCBI chr 5:137,551,784...137,567,844
Ensembl chr 5:137,551,779...137,567,844
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Adam30
a disintegrin and metallopeptidase domain 30
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ADAM30 mRNA
CTD
PMID:34925699
NCBI chr 3:98,067,950...98,071,485
Ensembl chr 3:98,067,946...98,071,485
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Adam32
a disintegrin and metallopeptidase domain 32
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ADAM32 mRNA
CTD
PMID:34925699
NCBI chr 8:25,326,159...25,438,933
Ensembl chr 8:25,326,156...25,438,820
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Adam33
a disintegrin and metallopeptidase domain 33
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ADAM33 mRNA
CTD
PMID:34925699
NCBI chr 2:130,892,739...130,905,734
Ensembl chr 2:130,892,511...130,905,734
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Adamts5
ADAM metallopeptidase with thrombospondin type 1 motif 5
multiple interactions
ISO
theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of ADAMTS5 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of ADAMTS5 protein]
CTD
PMID:35847580
NCBI chr16:85,655,045...85,698,013
Ensembl chr16:85,653,061...85,698,716
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Add2
adducin 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ADD2 mRNA
CTD
PMID:34925699
NCBI chr 6:86,005,663...86,101,391
Ensembl chr 6:86,005,663...86,101,391
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Adgrf2
adhesion G protein-coupled receptor F2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ADGRF2P mRNA
CTD
PMID:34925699
NCBI chr17:43,004,919...43,054,646
Ensembl chr17:43,007,021...43,053,070
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Adgrg7
adhesion G protein-coupled receptor G7
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ADGRG7 mRNA
CTD
PMID:34925699
NCBI chr16:56,544,972...56,616,369
Ensembl chr16:56,544,972...56,616,218
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Adipoq
adiponectin, C1Q and collagen domain containing
multiple interactions
EXP
theaflavin-3,3'-digallate inhibits the reaction [Methylmercury Compounds results in increased secretion of ADIPOQ protein]
CTD
PMID:31195622
NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778
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Adra2b
adrenergic receptor, alpha 2b
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ADRA2B mRNA
CTD
PMID:34925699
NCBI chr 2:127,205,099...127,209,141
Ensembl chr 2:127,205,128...127,209,141
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Adtrp
androgen dependent TFPI regulating protein
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ADTRP mRNA
CTD
PMID:34925699
NCBI chr13:41,916,621...42,001,092
Ensembl chr13:41,916,624...42,001,160
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Agt
angiotensinogen
multiple interactions
ISO
theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in decreased abundance of Nitric Oxide]; theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in decreased activity of CAT protein]; theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in decreased phosphorylation of NFATC3 protein]; theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]; theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in increased expression of ANP mRNA]; theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in increased expression of BNP mRNA]; theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in increased expression of PPP3CA protein]
CTD
PMID:35406003
NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445
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Ahr
aryl-hydrocarbon receptor
multiple interactions
ISO
theaflavin-3,3'-digallate inhibits the reaction [Tetrachlorodibenzodioxin binds to and affects the activity of AHR protein]
CTD
PMID:15914905
NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
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Aipl1
aryl hydrocarbon receptor-interacting protein-like 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of AIPL1 mRNA
CTD
PMID:34925699
NCBI chr11:71,919,527...71,933,184
Ensembl chr11:71,918,789...71,928,335
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Akt1
thymoma viral proto-oncogene 1
multiple interactions
ISO
theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of AKT1 protein]; theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in increased phosphorylation of AKT1 protein] theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein]
CTD
PMID:12931129 PMID:35847580 PMID:35903325
NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
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Allc
allantoicase
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ALLC mRNA
CTD
PMID:34925699
NCBI chr12:28,603,754...28,632,527
Ensembl chr12:28,603,754...28,632,522
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Alppl2
alkaline phosphatase, placental-like 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ALPPL2 mRNA
CTD
PMID:34925699
NCBI chr 1:87,014,412...87,023,656
Ensembl chr 1:87,014,416...87,017,650
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Amh
anti-Mullerian hormone
increases expression
EXP
theaflavin-3,3'-digallate results in increased expression of AMH mRNA
CTD
PMID:34925699
NCBI chr10:80,641,074...80,643,513
Ensembl chr10:80,641,077...80,643,482
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Ampd1
adenosine monophosphate deaminase 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of AMPD1 mRNA
CTD
PMID:34925699
NCBI chr 3:102,981,330...103,007,038
Ensembl chr 3:102,981,330...103,007,036
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Amz1
archaelysin family metallopeptidase 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of AMZ1 mRNA
CTD
PMID:34925699
NCBI chr 5:140,709,882...140,739,067
Ensembl chr 5:140,709,882...140,747,194
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Ang
angiogenin, ribonuclease, RNase A family, 5
multiple interactions decreases secretion
ISO
[Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased secretion of ANG protein theaflavin-3,3'-digallate results in decreased secretion of ANG protein
CTD
PMID:34350509
NCBI chr14:51,328,607...51,339,462
Ensembl chr14:51,328,607...51,339,466
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Ankub1
ankyrin repeat and ubiquitin domain containing 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ANKUB1 mRNA
CTD
PMID:34925699
NCBI chr 3:57,574,843...57,599,958
Ensembl chr 3:57,564,814...57,600,220
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Apoa4
apolipoprotein A-IV
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of APOA4 mRNA
CTD
PMID:34925699
NCBI chr 9:46,152,142...46,154,756
Ensembl chr 9:46,151,994...46,154,757
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Apol9a
apolipoprotein L 9a
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of APOL4 mRNA
CTD
PMID:34925699
NCBI chr15:77,287,989...77,295,280
Ensembl chr15:77,287,989...77,295,335
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Arc
activity regulated cytoskeletal-associated protein
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ARC mRNA
CTD
PMID:34925699
NCBI chr15:74,540,930...74,544,419
Ensembl chr15:74,540,932...74,544,419
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Areg
amphiregulin
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of AREG mRNA
CTD
PMID:34925699
NCBI chr 5:91,287,458...91,296,291
Ensembl chr 5:91,287,458...91,296,291
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Asb15
ankyrin repeat and SOCS box-containing 15
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ASB15 mRNA
CTD
PMID:34925699
NCBI chr 6:24,528,143...24,573,163
Ensembl chr 6:24,528,143...24,573,163
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Asic4
acid-sensing ion channel family member 4
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ASIC4 mRNA
CTD
PMID:34925699
NCBI chr 1:75,426,467...75,450,984
Ensembl chr 1:75,427,080...75,450,987
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Atoh1
atonal bHLH transcription factor 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ATOH1 mRNA
CTD
PMID:34925699
NCBI chr 6:64,706,109...64,708,229
Ensembl chr 6:64,706,109...64,708,229
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Atp10b
ATPase, class V, type 10B
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ATP10B mRNA
CTD
PMID:34925699
NCBI chr11:42,902,991...43,153,112
Ensembl chr11:43,040,704...43,153,112
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Atp1a4
ATPase, Na+/K+ transporting, alpha 4 polypeptide
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ATP1A4 mRNA
CTD
PMID:34925699
NCBI chr 1:172,051,075...172,085,991
Ensembl chr 1:172,051,080...172,085,981
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Atp1b4
ATPase Na+/K+ transporting, beta 4 polypeptide
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ATP1B4 mRNA
CTD
PMID:34925699
NCBI chr X:37,404,999...37,425,661
Ensembl chr X:37,405,061...37,425,646
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Atp2a1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ATP2A1 mRNA
CTD
PMID:34925699
NCBI chr 7:126,045,032...126,062,245
Ensembl chr 7:126,045,030...126,062,280
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Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ATP2B2 mRNA
CTD
PMID:34925699
NCBI chr 6:113,720,803...114,019,574
Ensembl chr 6:113,720,792...114,019,574
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Avil
advillin
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of AVIL mRNA
CTD
PMID:34925699
NCBI chr10:126,835,933...126,856,857
Ensembl chr10:126,836,578...126,856,863
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Baat
bile acid-Coenzyme A: amino acid N-acyltransferase
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of BAAT mRNA
CTD
PMID:34925699
NCBI chr 4:49,489,416...49,507,915
Ensembl chr 4:49,489,422...49,506,557
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Bax
BCL2-associated X protein
decreases expression multiple interactions increases expression
ISO
theaflavin-3,3'-digallate results in decreased expression of BAX protein [Methotrexate co-treated with theaflavin-3,3'-digallate] results in increased expression of BAX protein theaflavin-3,3'-digallate results in increased expression of BAX protein theaflavin-3,3'-digallate results in decreased expression of BAX mRNA; theaflavin-3,3'-digallate results in decreased expression of BAX protein
CTD
PMID:30769778 PMID:32964953 PMID:34350509 PMID:34925699
NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
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BC034090
cDNA sequence BC034090
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of KIAA1614 mRNA
CTD
PMID:34925699
NCBI chr 1:155,088,217...155,123,504
Ensembl chr 1:155,088,217...155,120,190
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Bcl2
B cell leukemia/lymphoma 2
decreases expression increases expression multiple interactions
ISO
theaflavin-3,3'-digallate results in decreased expression of BCL2 protein theaflavin-3,3'-digallate results in increased expression of BCL2 mRNA; theaflavin-3,3'-digallate results in increased expression of BCL2 protein [Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased expression of BCL2 protein
CTD
PMID:32964953 PMID:34350509
NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
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Bcl2l1
BCL2-like 1
decreases expression
ISO
theaflavin-3,3'-digallate results in decreased expression of BCL2L1 protein
CTD
PMID:30769778
NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648
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Becn1
beclin 1, autophagy related
multiple interactions decreases expression
ISO
[Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased expression of BECN1 protein theaflavin-3,3'-digallate results in decreased expression of BECN1 protein
CTD
PMID:34350509
NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112
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Bglap
bone gamma carboxyglutamate protein
multiple interactions
EXP
theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased expression of BGLAP protein]; theaflavin-3,3'-digallate results in increased expression of and results in increased secretion of BGLAP protein
CTD
PMID:33833684
NCBI chr 3:88,290,802...88,291,773
Ensembl chr 3:88,290,808...88,291,771
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Bmp15
bone morphogenetic protein 15
increases expression
EXP
theaflavin-3,3'-digallate results in increased expression of BMP15 mRNA
CTD
PMID:34925699
NCBI chr X:6,226,108...6,232,778
Ensembl chr X:6,226,161...6,232,775
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Bnc1
basonuclin zinc finger protein 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of BNC1 mRNA
CTD
PMID:34925699
NCBI chr 7:81,616,401...81,642,047
Ensembl chr 7:81,616,401...81,642,055
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Bnipl
BCL2/adenovirus E1B 19kD interacting protein like
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of BNIPL mRNA
CTD
PMID:34925699
NCBI chr 3:95,148,587...95,158,504
Ensembl chr 3:95,148,582...95,158,504
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Bop1
block of proliferation 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of BOP1 mRNA
CTD
PMID:34925699
NCBI chr15:76,337,188...76,361,449
Ensembl chr15:76,337,189...76,361,477
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Btla
B and T lymphocyte associated
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of BTLA mRNA
CTD
PMID:34925699
NCBI chr16:45,043,121...45,073,258
Ensembl chr16:45,044,678...45,078,033
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Btn1a1
butyrophilin, subfamily 1, member A1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of BTN1A1 mRNA
CTD
PMID:34925699
NCBI chr13:23,641,154...23,650,084
Ensembl chr13:23,641,162...23,650,071
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Bysl
bystin-like
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of BYSL mRNA
CTD
PMID:34925699
NCBI chr17:47,910,256...47,922,417
Ensembl chr17:47,910,256...47,922,417
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C1qtnf2
C1q and tumor necrosis factor related protein 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of C1QTNF2 mRNA
CTD
PMID:34925699
NCBI chr11:43,364,984...43,382,485
Ensembl chr11:43,365,103...43,382,352
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C5ar2
complement component 5a receptor 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of C5AR2 mRNA
CTD
PMID:34925699
NCBI chr 7:15,968,512...15,978,079
Ensembl chr 7:15,968,510...15,978,079
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C9
complement component 9
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of C9 mRNA
CTD
PMID:34925699
NCBI chr15:6,474,827...6,528,306
Ensembl chr15:6,474,808...6,528,232
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Capn11
calpain 11
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CAPN11 mRNA
CTD
PMID:34925699
NCBI chr17:45,941,117...45,970,400
Ensembl chr17:45,941,130...45,970,251
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Casp3
caspase 3
increases activity decreases expression multiple interactions
ISO
theaflavin-3,3'-digallate results in increased activity of CASP3 protein theaflavin-3,3'-digallate results in decreased expression of CASP3 protein theaflavin-3,3'-digallate results in decreased expression of CASP3 mRNA; theaflavin-3,3'-digallate results in decreased expression of CASP3 protein [Methotrexate co-treated with theaflavin-3,3'-digallate] results in increased expression of and results in increased cleavage of and results in increased activity of CASP3 protein; theaflavin-3,3'-digallate results in increased expression of and results in increased cleavage of and results in increased activity of CASP3 protein
CTD
PMID:30769778 PMID:32964953 PMID:34350509 PMID:34925699
NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
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Casp8
caspase 8
increases activity
ISO
theaflavin-3,3'-digallate results in increased activity of CASP8 protein
CTD
PMID:30769778
NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
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Casp9
caspase 9
multiple interactions increases activity
ISO
[Methotrexate co-treated with theaflavin-3,3'-digallate] results in increased expression of and results in increased cleavage of and results in increased activity of CASP9 protein; theaflavin-3,3'-digallate results in increased expression of and results in increased cleavage of and results in increased activity of CASP9 protein theaflavin-3,3'-digallate results in increased activity of CASP9 protein
CTD
PMID:30769778 PMID:34350509
NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
G
Cass4
Cas scaffolding protein family member 4
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CASS4 mRNA
CTD
PMID:34925699
NCBI chr 2:172,234,998...172,275,672
Ensembl chr 2:172,235,714...172,275,677
G
Cat
catalase
multiple interactions
ISO EXP
theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in decreased activity of CAT protein] theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in decreased expression of CAT mRNA]
CTD
PMID:32694992 PMID:35406003
NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
G
Cc2d2b
coiled-coil and C2 domain containing 2B
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CC2D2B mRNA
CTD
PMID:34925699
NCBI chr19:40,737,197...40,818,227
Ensembl chr19:40,737,197...40,816,187
G
Ccdc17
coiled-coil domain containing 17
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CCDC17 mRNA
CTD
PMID:34925699
NCBI chr 4:116,453,927...116,457,463
Ensembl chr 4:116,453,851...116,457,463
G
Ccdc62
coiled-coil domain containing 62
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CCDC62 mRNA
CTD
PMID:34925699
NCBI chr 5:124,068,683...124,107,958
Ensembl chr 5:124,065,481...124,107,958
G
Ccdc65
coiled-coil domain containing 65
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CCDC65 mRNA
CTD
PMID:34925699
NCBI chr15:98,606,075...98,621,221
Ensembl chr15:98,606,088...98,621,217
G
Ccdc70
coiled-coil domain containing 70
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CCDC70 mRNA
CTD
PMID:34925699
NCBI chr 8:22,459,791...22,464,071
Ensembl chr 8:22,459,791...22,464,057
G
Ccl4
C-C motif chemokine ligand 4
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CCL4 mRNA
CTD
PMID:34925699
NCBI chr11:83,553,410...83,555,509
Ensembl chr11:83,553,410...83,555,509
G
Ccnd1
cyclin D1
multiple interactions decreases expression
ISO
CDKN1B promotes the reaction [theaflavin-3,3'-digallate results in decreased expression of CCND1 protein]
CTD
PMID:30769778
NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
G
Ccr1
C-C motif chemokine receptor 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CCR1 mRNA
CTD
PMID:34925699
NCBI chr 9:123,762,163...123,768,729
Ensembl chr 9:123,762,161...123,768,729
G
Ccr6
C-C motif chemokine receptor 6
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CCR6 mRNA
CTD
PMID:34925699
NCBI chr17:8,454,875...8,477,353
Ensembl chr17:8,454,875...8,475,973
G
Cd300e
CD300E molecule
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CD300E mRNA
CTD
PMID:34925699
NCBI chr11:114,942,743...114,957,502
Ensembl chr11:114,942,743...114,957,500
G
Cd33
CD33 molecule
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CD33 mRNA
CTD
PMID:34925699
NCBI chr 7:43,176,823...43,186,679
Ensembl chr 7:43,173,640...43,193,852
G
Cd3g
CD3 antigen, gamma polypeptide
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CD3G mRNA
CTD
PMID:34925699
NCBI chr 9:44,880,870...44,891,729
Ensembl chr 9:44,880,870...44,891,729
G
Cd40
CD40 antigen
multiple interactions
EXP
theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in increased expression of CD40 mRNA]
CTD
PMID:32694992
NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868
G
Cd69
CD69 antigen
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CD69 mRNA
CTD
PMID:34925699
NCBI chr 6:129,244,287...129,252,332
Ensembl chr 6:129,244,288...129,252,399
G
Cdc42ep1
CDC42 effector protein 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CDC42EP1 mRNA
CTD
PMID:34925699
NCBI chr15:78,726,847...78,735,102
Ensembl chr15:78,726,824...78,735,097
G
Cdk4
cyclin dependent kinase 4
decreases expression multiple interactions
ISO
theaflavin-3,3'-digallate results in decreased expression of CDK4 protein CDKN1B promotes the reaction [theaflavin-3,3'-digallate results in decreased expression of CDK4 protein]
CTD
PMID:30769778
NCBI chr10:126,899,404...126,903,157
Ensembl chr10:126,899,403...126,903,789
G
Cdk5r1
cyclin dependent kinase 5, regulatory subunit 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CDK5R1 mRNA
CTD
PMID:34925699
NCBI chr11:80,367,849...80,372,010
Ensembl chr11:80,367,849...80,372,010
G
Cdkn1b
cyclin dependent kinase inhibitor 1B
increases expression multiple interactions
ISO
theaflavin-3,3'-digallate results in increased expression of CDKN1B protein CDKN1B promotes the reaction [theaflavin-3,3'-digallate results in decreased expression of and results in decreased phosphorylation of RB1 protein]; CDKN1B promotes the reaction [theaflavin-3,3'-digallate results in decreased expression of CCND1 protein]; CDKN1B promotes the reaction [theaflavin-3,3'-digallate results in decreased expression of CDK4 protein]
CTD
PMID:30769778
NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476
G
Cdx2
caudal type homeobox 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CDX2 mRNA
CTD
PMID:34925699
NCBI chr 5:147,237,710...147,244,059
Ensembl chr 5:147,237,615...147,244,080
G
Ceacam10
CEA cell adhesion molecule 10
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CEACAM4 mRNA
CTD
PMID:34925699
NCBI chr 7:24,476,592...24,484,081
Ensembl chr 7:24,476,631...24,484,082
G
Cebpa
CCAAT/enhancer binding protein alpha
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CEBPA mRNA
CTD
PMID:34925699
NCBI chr 7:34,818,718...34,821,353
Ensembl chr 7:34,818,718...34,821,353
G
Cfap141
cilia and flagella associated protein 141
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CFAP141 mRNA
CTD
PMID:34925699
NCBI chr 3:89,970,115...89,975,654
Ensembl chr 3:89,970,103...89,973,182
G
Cfap161
cilia and flagella associated protein 161
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CFAP161 mRNA
CTD
PMID:34925699
NCBI chr 7:83,424,820...83,447,528
Ensembl chr 7:83,423,309...83,444,088
G
Cfap206
cilia and flagella associated protein 206
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CFAP206 mRNA
CTD
PMID:34925699
NCBI chr 4:34,688,574...34,730,263
Ensembl chr 4:34,688,559...34,730,206
G
Cfap276
cilia and flagella associated protein 276
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CFAP276 mRNA
CTD
PMID:34925699
NCBI chr 3:108,444,900...108,452,013
Ensembl chr 3:108,441,466...108,452,039
G
Chac1
ChaC, cation transport regulator 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CHAC1 mRNA
CTD
PMID:34925699
NCBI chr 2:119,181,723...119,184,807
Ensembl chr 2:119,181,710...119,184,862
G
Chd5
chromodomain helicase DNA binding protein 5
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CHD5 mRNA
CTD
PMID:34925699
NCBI chr 4:152,423,103...152,474,651
Ensembl chr 4:152,423,108...152,474,651
G
Chek2
checkpoint kinase 2
increases phosphorylation
ISO
theaflavin-3,3'-digallate results in increased phosphorylation of CHEK2 protein
CTD
PMID:30769778
NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011
G
Chrm5
cholinergic receptor, muscarinic 5
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CHRM5 mRNA
CTD
PMID:34925699
NCBI chr 2:112,306,055...112,365,487
Ensembl chr 2:112,309,516...112,311,114
G
Chrna3
cholinergic receptor, nicotinic, alpha polypeptide 3
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CHRNA3 mRNA
CTD
PMID:34925699
NCBI chr 9:54,917,401...54,933,846
Ensembl chr 9:54,917,395...54,933,846
G
Chrna4
cholinergic receptor, nicotinic, alpha polypeptide 4
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CHRNA4 mRNA
CTD
PMID:34925699
NCBI chr 2:180,664,104...180,685,339
Ensembl chr 2:180,660,173...180,685,339
G
Clcn1
chloride channel, voltage-sensitive 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CLCN1 mRNA
CTD
PMID:34925699
NCBI chr 6:42,263,552...42,292,693
Ensembl chr 6:42,263,619...42,292,690
G
Cldn19
claudin 19
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CLDN19 mRNA
CTD
PMID:34925699
NCBI chr 4:119,112,638...119,119,635
Ensembl chr 4:119,112,611...119,119,635
G
Clec4a1
C-type lectin domain family 4, member a1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ZNF705A mRNA
CTD
PMID:34925699
NCBI chr 6:122,898,807...122,911,578
Ensembl chr 6:122,898,807...122,911,578
G
Clec5a
C-type lectin domain family 5, member a
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CLEC5A mRNA
CTD
PMID:34925699
NCBI chr 6:40,551,832...40,562,739
Ensembl chr 6:40,551,828...40,562,755
G
Clec7a
C-type lectin domain family 7, member a
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CLEC7A mRNA
CTD
PMID:34925699
NCBI chr 6:129,438,554...129,449,748
Ensembl chr 6:129,438,554...129,449,742
G
Cmtm2b
CKLF-like MARVEL transmembrane domain containing 2B
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CMTM2 mRNA
CTD
PMID:34925699
NCBI chr 8:105,048,838...105,057,396
Ensembl chr 8:105,048,862...105,057,396
G
Cnbd2
cyclic nucleotide binding domain containing 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CNBD2 mRNA
CTD
PMID:34925699
NCBI chr 2:156,153,866...156,217,558
Ensembl chr 2:156,154,219...156,217,558
G
Cndp1
carnosine dipeptidase 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CNDP1 mRNA
CTD
PMID:34925699
NCBI chr18:84,628,509...84,668,359
Ensembl chr18:84,628,634...84,668,220
G
Cnr1
cannabinoid receptor 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CNR1 mRNA
CTD
PMID:34925699
NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831
G
Col11a2
collagen, type XI, alpha 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of COL11A2 mRNA
CTD
PMID:34925699
NCBI chr17:34,257,462...34,285,659
Ensembl chr17:34,258,411...34,285,659
G
Col2a1
collagen, type II, alpha 1
multiple interactions
ISO
theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of COL2A1 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of COL2A1 protein]
CTD
PMID:35847580
NCBI chr15:97,873,483...97,902,525
Ensembl chr15:97,873,483...97,902,576
G
Cplx3
complexin 3
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CPLX3 mRNA
CTD
PMID:34925699
NCBI chr 9:57,507,275...57,513,564
Ensembl chr 9:57,507,275...57,513,564
G
Cr2
complement receptor 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CR2 mRNA
CTD
PMID:34925699
NCBI chr 1:194,819,120...194,859,096
Ensembl chr 1:194,819,119...194,859,024
G
Crybb2
crystallin, beta B2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CRYBB2 mRNA
CTD
PMID:34925699
NCBI chr 5:113,206,124...113,217,983
Ensembl chr 5:113,206,124...113,217,983
G
Ctnnb1
catenin beta 1
multiple interactions
EXP
theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased expression of CTNNB1 protein]
CTD
PMID:33833684
NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
G
Ctsk
cathepsin K
multiple interactions
EXP
theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA]
CTD
PMID:32694992
NCBI chr 3:95,406,521...95,416,698
Ensembl chr 3:95,406,567...95,416,673
G
Ctsl
cathepsin L
decreases expression
ISO
theaflavin-3,3'-digallate results in decreased expression of CTSL protein
CTD
PMID:34138966
NCBI chr13:64,509,704...64,518,586
Ensembl chr13:64,507,151...64,518,704
G
Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
multiple interactions
EXP
theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of CYP1A2 mRNA]
CTD
PMID:36105184
NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
G
Cyp26a1
cytochrome P450, family 26, subfamily a, polypeptide 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CYP26A1 mRNA
CTD
PMID:34925699
NCBI chr19:37,686,186...37,689,984
Ensembl chr19:37,686,246...37,689,984
G
Cyp2b10
cytochrome P450, family 2, subfamily b, polypeptide 10
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CYP2B6 mRNA
CTD
PMID:34925699
NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049
G
Cyp2c70
cytochrome P450, family 2, subfamily c, polypeptide 70
multiple interactions
EXP
theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of CYP2C70 mRNA]
CTD
PMID:36105184
NCBI chr19:40,141,805...40,175,730
Ensembl chr19:40,141,797...40,175,777
G
Cyp4b1
cytochrome P450, family 4, subfamily b, polypeptide 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CYP4B1 mRNA
CTD
PMID:34925699
NCBI chr 4:115,481,895...115,504,918
Ensembl chr 4:115,481,922...115,504,920
G
Cyp4f14
cytochrome P450, family 4, subfamily f, polypeptide 14
multiple interactions affects expression
EXP ISO
theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of CYP4F14 mRNA] theaflavin-3,3'-digallate affects the expression of CYP4F12 mRNA
CTD
PMID:34925699 PMID:36105184
NCBI chr17:33,122,331...33,136,353
Ensembl chr17:33,124,044...33,136,316
G
Cyp7a1
cytochrome P450, family 7, subfamily a, polypeptide 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of CYP7A1 mRNA
CTD
PMID:34925699
NCBI chr 4:6,265,612...6,275,632
Ensembl chr 4:6,265,612...6,275,633
G
D630039A03Rik
RIKEN cDNA D630039A03 gene
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of C9ORF152 mRNA
CTD
PMID:34925699
NCBI chr 4:57,908,384...57,916,264
Ensembl chr 4:57,908,483...57,916,297
G
Dcaf12l1
DDB1 and CUL4 associated factor 12-like 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of DCAF12L1 mRNA
CTD
PMID:34925699
NCBI chr X:43,875,444...43,879,074
Ensembl chr X:43,875,447...43,879,074
G
Ddit3
DNA-damage inducible transcript 3
multiple interactions affects expression
ISO
[Methotrexate co-treated with theaflavin-3,3'-digallate] results in increased expression of DDIT3 protein theaflavin-3,3'-digallate affects the expression of DDIT3 mRNA
CTD
PMID:34350509 PMID:34925699
NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157 Ensembl chr10:127,126,643...127,132,157
G
Dgkb
diacylglycerol kinase, beta
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of DGKB mRNA
CTD
PMID:34925699
NCBI chr12:37,930,169...38,684,238
Ensembl chr12:37,867,725...38,684,238
G
Dhcr7
7-dehydrocholesterol reductase
multiple interactions
EXP
theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of DHCR7 mRNA]
CTD
PMID:36105184
NCBI chr 7:143,376,827...143,402,147
Ensembl chr 7:143,376,882...143,402,147
G
Dhrs9
dehydrogenase/reductase 9
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of DHRS9 mRNA
CTD
PMID:34925699
NCBI chr 2:69,210,806...69,233,430
Ensembl chr 2:69,210,789...69,234,877
G
Dkk4
dickkopf WNT signaling pathway inhibitor 4
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of DKK4 mRNA
CTD
PMID:34925699
NCBI chr 8:23,113,701...23,117,563
Ensembl chr 8:23,114,059...23,117,563
G
Dlx1
distal-less homeobox 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of DLX1 mRNA
CTD
PMID:34925699
NCBI chr 2:71,358,457...71,364,325
Ensembl chr 2:71,358,457...71,364,325
G
Dnaaf1
dynein, axonemal assembly factor 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of DNAAF1 mRNA
CTD
PMID:34925699
NCBI chr 8:120,301,974...120,325,193
Ensembl chr 8:120,301,974...120,325,193
G
Dnah11
dynein, axonemal, heavy chain 11
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of DNAH11 mRNA
CTD
PMID:34925699
NCBI chr12:117,841,717...118,162,778
Ensembl chr12:117,841,717...118,162,778
G
Dnah12
dynein, axonemal, heavy chain 12
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of DNAH12 mRNA
CTD
PMID:34925699
NCBI chr14:26,412,709...26,614,250
Ensembl chr14:26,414,429...26,613,660
G
Dnase2b
deoxyribonuclease II beta
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of DNASE2B mRNA
CTD
PMID:34925699
NCBI chr 3:146,275,488...146,322,815
Ensembl chr 3:146,286,740...146,321,351
G
Dok2
docking protein 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of DOK2 mRNA
CTD
PMID:34925699
NCBI chr14:71,003,336...71,015,934
Ensembl chr14:71,003,476...71,015,935
G
Dppa3
developmental pluripotency-associated 3
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of DPPA3 mRNA
CTD
PMID:34925699
NCBI chr 6:122,603,383...122,607,230
Ensembl chr 6:122,603,369...122,607,231
G
Dppa5a
developmental pluripotency associated 5A
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of DPPA5 mRNA
CTD
PMID:34925699
NCBI chr 9:78,274,334...78,275,481
Ensembl chr 9:78,274,334...78,275,459
G
Drc7
dynein regulatory complex subunit 7
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of DRC7 mRNA
CTD
PMID:34925699
NCBI chr 8:95,781,731...95,804,769
Ensembl chr 8:95,781,731...95,804,769
G
Dscaml1
DS cell adhesion molecule like 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of DSCAML1 mRNA
CTD
PMID:34925699
NCBI chr 9:45,338,735...45,665,011
Ensembl chr 9:45,337,926...45,665,010
G
Ebp
EBP cholestenol delta-isomerase
multiple interactions
EXP
theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of EBP mRNA]
CTD
PMID:36105184
NCBI chr X:8,051,568...8,059,751
Ensembl chr X:8,051,568...8,059,751
G
Edn1
endothelin 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of EDN1 mRNA
CTD
PMID:34925699
NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
G
Efnb1
ephrin B1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of EFNB1 mRNA
CTD
PMID:34925699
NCBI chr X:98,179,667...98,192,628
Ensembl chr X:98,179,736...98,192,597
G
Egf
epidermal growth factor
multiple interactions
EXP ISO
theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased phosphorylation of and results in increased activity of EGFR protein]; theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein] theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased activity of SP1 protein]; theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased expression of FAS mRNA]; theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased expression of FAS protein]; theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein]
CTD
PMID:12931129 PMID:16353237
NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965
G
Egfr
epidermal growth factor receptor
multiple interactions
EXP ISO
theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased phosphorylation of and results in increased activity of EGFR protein] theaflavin-3,3'-digallate results in increased ubiquitination of and results in increased degradation of and results in decreased expression of EGFR protein [theaflavin co-treated with theaflavine gallate co-treated with theaflavin-3,3'-digallate] inhibits the reaction [Tobacco Smoke Pollution results in increased expression of and results in increased phosphorylation of EGFR protein]; [theaflavin co-treated with theaflavine gallate co-treated with theaflavin-3,3'-digallate] inhibits the reaction [Tobacco Smoke Pollution results in increased expression of EGFR mRNA]
CTD
PMID:16353237 PMID:21475988
NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
G
Elovl1
ELOVL fatty acid elongase 1
multiple interactions
EXP
theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of ELOVL1 mRNA]
CTD
PMID:36105184
NCBI chr 4:118,285,321...118,290,150
Ensembl chr 4:118,285,290...118,290,150
G
Epha8
Eph receptor A8
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of EPHA8 mRNA
CTD
PMID:34925699
NCBI chr 4:136,656,729...136,684,170
Ensembl chr 4:136,656,730...136,684,127
G
Ermn
ermin, ERM-like protein
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ERMN mRNA
CTD
PMID:34925699
NCBI chr 2:57,874,920...57,942,962
Ensembl chr 2:57,935,125...57,942,876
G
Ern1
endoplasmic reticulum to nucleus signalling 1
multiple interactions decreases expression
ISO
[Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased expression of ERN1 mRNA theaflavin-3,3'-digallate results in decreased expression of ERN1 mRNA
CTD
PMID:34350509
NCBI chr11:106,285,474...106,378,701
Ensembl chr11:106,285,476...106,378,678
G
Errfi1
ERBB receptor feedback inhibitor 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ERRFI1 mRNA
CTD
PMID:34925699
NCBI chr 4:150,938,253...150,953,346
Ensembl chr 4:150,938,376...150,953,349
G
Evpl
envoplakin
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of EVPL mRNA
CTD
PMID:34925699
NCBI chr11:116,111,385...116,128,983
Ensembl chr11:116,111,385...116,128,903
G
Ezhip
EZH inhibitory protein
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of EZHIP mRNA
CTD
PMID:34925699
NCBI chr X:5,993,272...5,995,474
Ensembl chr X:5,993,273...5,995,473
G
F11
coagulation factor XI
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of F11 mRNA
CTD
PMID:34925699
NCBI chr 8:45,693,696...45,715,092
Ensembl chr 8:45,694,211...45,715,068
G
F13b
coagulation factor XIII, beta subunit
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of F13B mRNA
CTD
PMID:34925699
NCBI chr 1:139,429,285...139,451,496
Ensembl chr 1:139,429,440...139,451,490
G
F2
coagulation factor II
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of F2 mRNA
CTD
PMID:34925699
NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759
G
F2rl3
F2R like thrombin or trypsin receptor 3
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of F2RL3 mRNA
CTD
PMID:34925699
NCBI chr 8:73,488,287...73,490,526
Ensembl chr 8:73,488,508...73,490,502
G
F3
coagulation factor III
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of F3 mRNA
CTD
PMID:34925699
NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
G
Fabp12
fatty acid binding protein 12
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of FABP12 mRNA
CTD
PMID:34925699
NCBI chr 3:10,309,269...10,366,575
Ensembl chr 3:10,309,269...10,366,243
G
Fabp4
fatty acid binding protein 4, adipocyte
multiple interactions
EXP
theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of FABP4 mRNA]
CTD
PMID:36105184
NCBI chr 3:10,269,406...10,273,653
Ensembl chr 3:10,269,148...10,273,636
G
Fads1
fatty acid desaturase 1
multiple interactions
EXP
theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of FADS1 mRNA]
CTD
PMID:36105184
NCBI chr19:10,160,245...10,174,238
Ensembl chr19:10,160,252...10,174,241
G
Fam177b
family with sequence similarity 177 member B
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of FAM177B mRNA
CTD
PMID:34925699
NCBI chr 1:183,010,580...183,057,296
G
Fam180a
family with sequence similarity 180, member A
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of FAM180A mRNA
CTD
PMID:34925699
NCBI chr 6:35,289,678...35,303,076
Ensembl chr 6:35,289,603...35,303,076
G
Fam83c
family with sequence similarity 83, member C
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of FAM83C mRNA
CTD
PMID:34925699
NCBI chr 2:155,671,103...155,676,772
Ensembl chr 2:155,669,468...155,676,774
G
Fas
Fas cell surface death receptor
multiple interactions increases expression
ISO
theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased expression of FAS mRNA]; theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased expression of FAS protein] theaflavin-3,3'-digallate results in increased expression of FAS protein
CTD
PMID:12931129 PMID:30769778
NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
G
Fasl
Fas ligand
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of FASLG mRNA
CTD
PMID:34925699
NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
G
Fcamr
Fc receptor, IgA, IgM, high affinity
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of FCAMR mRNA
CTD
PMID:34925699
NCBI chr 1:130,712,444...130,753,641
Ensembl chr 1:130,728,639...130,742,477
G
Fcna
ficolin A
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of FCN3 mRNA
CTD
PMID:34925699
NCBI chr 2:25,514,677...25,525,448
Ensembl chr 2:25,514,678...25,518,042
G
Fcrl5
Fc receptor-like 5
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of FCRL5 mRNA
CTD
PMID:34925699
NCBI chr 3:87,343,084...87,407,985
Ensembl chr 3:87,343,080...87,407,985
G
Fcrl6
Fc receptor-like 6
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of FCRL6 mRNA
CTD
PMID:34925699
NCBI chr 1:172,423,081...172,445,889
Ensembl chr 1:172,424,209...172,430,118
G
Fdft1
farnesyl diphosphate farnesyl transferase 1
multiple interactions
EXP
theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of FDFT1 mRNA]
CTD
PMID:36105184
NCBI chr14:63,382,599...63,419,136
Ensembl chr14:63,382,599...63,417,027
G
Fgd2
FYVE, RhoGEF and PH domain containing 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of FGD2 mRNA
CTD
PMID:34925699
NCBI chr17:29,579,878...29,598,509
Ensembl chr17:29,579,888...29,598,635
G
Fgf17
fibroblast growth factor 17
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of FGF17 mRNA
CTD
PMID:34925699
NCBI chr14:70,873,643...70,880,064
Ensembl chr14:70,873,643...70,879,708
G
Fgf18
fibroblast growth factor 18
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of FGF18 mRNA
CTD
PMID:34925699
NCBI chr11:33,066,970...33,097,400
Ensembl chr11:33,067,430...33,097,400
G
Fli1
Friend leukemia integration 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of FLI1 mRNA
CTD
PMID:34925699
NCBI chr 9:32,333,500...32,454,292
Ensembl chr 9:32,333,500...32,454,157
G
Fndc7
fibronectin type III domain containing 7
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of FNDC7 mRNA
CTD
PMID:34925699
NCBI chr 3:108,760,898...108,797,324
Ensembl chr 3:108,760,994...108,797,324
G
Foxd3
forkhead box D3
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of FOXD3 mRNA
CTD
PMID:34925699
NCBI chr 4:99,544,536...99,546,908
Ensembl chr 4:99,544,536...99,546,859
G
Foxd4
forkhead box D4
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of FOXD4 mRNA
CTD
PMID:34925699
NCBI chr19:24,876,307...24,878,380
Ensembl chr19:24,876,600...24,878,561
G
Foxe3
forkhead box E3
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of FOXE3 mRNA
CTD
PMID:34925699
NCBI chr 4:114,781,640...114,783,264
Ensembl chr 4:114,782,344...114,783,210
G
Foxg1
forkhead box G1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of FOXG1 mRNA
CTD
PMID:34925699
NCBI chr12:49,429,666...49,433,650
Ensembl chr12:49,429,443...49,433,644
G
Foxl1
forkhead box L1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of FOXL1 mRNA
CTD
PMID:34925699
NCBI chr 8:121,854,572...121,857,383
Ensembl chr 8:121,854,679...121,857,383
G
Foxq1
forkhead box Q1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of FOXQ1 mRNA
CTD
PMID:34925699
NCBI chr13:31,742,153...31,744,959
Ensembl chr13:31,740,117...31,744,959
G
Frmd7
FERM domain containing 7
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of FRMD7 mRNA
CTD
PMID:34925699
NCBI chr X:49,980,044...50,032,493
Ensembl chr X:49,984,057...50,031,587
G
Frzb
frizzled-related protein
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of FRZB mRNA
CTD
PMID:34925699
NCBI chr 2:80,242,314...80,277,740
Ensembl chr 2:80,242,314...80,277,969
G
Fscn3
fascin actin-bundling protein 3
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of FSCN3 mRNA
CTD
PMID:34925699
NCBI chr 6:28,427,888...28,438,621
Ensembl chr 6:28,427,788...28,438,621
G
Gabrr1
gamma-aminobutyric acid type A receptor subunit rho 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of GABRR1 mRNA
CTD
PMID:34925699
NCBI chr 4:33,132,556...33,163,606
Ensembl chr 4:33,132,521...33,163,588
G
Galnt14
polypeptide N-acetylgalactosaminyltransferase 14
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of GALNT14 mRNA
CTD
PMID:34925699
NCBI chr17:73,800,202...74,019,138
Ensembl chr17:73,800,223...74,017,448
G
Garin1a
golgi associated RAB2 interactor 1A
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of GARIN1A mRNA
CTD
PMID:34925699
NCBI chr 6:29,276,298...29,290,684
Ensembl chr 6:29,279,592...29,290,679
G
Garin4
golgi associated RAB2 interactor family member 4
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of GARIN4 mRNA
CTD
PMID:34925699
NCBI chr 1:190,894,781...190,897,014
Ensembl chr 1:190,894,781...190,897,014
G
Gdf9
growth differentiation factor 9
increases expression affects expression
EXP ISO
theaflavin-3,3'-digallate results in increased expression of GDF9 mRNA theaflavin-3,3'-digallate affects the expression of GDF9 mRNA
CTD
PMID:34925699
NCBI chr11:53,321,773...53,328,731
Ensembl chr11:53,321,850...53,328,731
G
Gdpd3
glycerophosphodiester phosphodiesterase domain containing 3
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of GDPD3 mRNA
CTD
PMID:34925699
NCBI chr 7:126,365,586...126,374,817
Ensembl chr 7:126,365,506...126,374,821
G
Gfi1b
growth factor independent 1B
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of GFI1B mRNA
CTD
PMID:34925699
NCBI chr 2:28,499,462...28,511,994
Ensembl chr 2:28,499,462...28,511,994
G
Ghsr
growth hormone secretagogue receptor
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of GHSR mRNA
CTD
PMID:34925699
NCBI chr 3:27,425,500...27,433,384
Ensembl chr 3:27,425,500...27,432,159
G
Gjb1
gap junction protein, beta 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of GJB1 mRNA
CTD
PMID:34925699
NCBI chr X:100,419,982...100,429,235
Ensembl chr X:100,419,984...100,429,235
G
Gjd4
gap junction protein, delta 4
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of GJD4 mRNA
CTD
PMID:34925699
NCBI chr18:9,278,124...9,289,808
Ensembl chr18:9,278,607...9,282,809
G
Glt1d1
glycosyltransferase 1 domain containing 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of GLT1D1 mRNA
CTD
PMID:34925699
NCBI chr 5:127,709,134...127,786,438
Ensembl chr 5:127,709,326...127,786,438
G
Gnat1
G protein subunit alpha transducin 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of GNAT1 mRNA
CTD
PMID:34925699
NCBI chr 9:107,551,636...107,556,833
Ensembl chr 9:107,551,673...107,556,911
G
Gp5
glycoprotein 5 platelet
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of GP5 mRNA
CTD
PMID:34925699
NCBI chr16:30,126,503...30,129,599
Ensembl chr16:30,126,503...30,129,597
G
Gpbar1
G protein-coupled bile acid receptor 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of GPBAR1 mRNA
CTD
PMID:34925699
NCBI chr 1:74,316,269...74,318,868
Ensembl chr 1:74,317,709...74,318,783
G
Gpr162
G protein-coupled receptor 162
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of GPR162 mRNA
CTD
PMID:34925699
NCBI chr 6:124,835,407...124,840,900
Ensembl chr 6:124,835,407...124,840,946
G
Gpr19
G protein-coupled receptor 19
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of GPR19 mRNA
CTD
PMID:34925699
NCBI chr 6:134,846,055...134,875,157
Ensembl chr 6:134,846,056...134,875,541
G
Gpr25
G protein-coupled receptor 25
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of GPR25 mRNA
CTD
PMID:34925699
NCBI chr 1:136,186,652...136,188,664
Ensembl chr 1:136,187,535...136,188,611
G
Gpr82
G protein-coupled receptor 82
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of GPR82 mRNA
CTD
PMID:34925699
NCBI chr X:13,512,373...13,533,669
Ensembl chr X:13,527,602...13,533,672
G
Gpr83
G protein-coupled receptor 83
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of GPR83 mRNA
CTD
PMID:34925699
NCBI chr 9:14,771,038...14,782,085
Ensembl chr 9:14,771,506...14,782,085
G
Gpx1
glutathione peroxidase 1
multiple interactions
EXP
theaflavin-3,3'-digallate inhibits the reaction [Galactose results in decreased expression of GPX1 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in decreased expression of GPX1 mRNA]
CTD
PMID:32694992 PMID:36638877
NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
G
Gria2
glutamate receptor, ionotropic, AMPA2 (alpha 2)
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of GRIA2 mRNA
CTD
PMID:34925699
NCBI chr 3:80,588,757...80,711,534
Ensembl chr 3:80,588,757...80,710,142
G
Gsdmc2
gasdermin C2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of GSDMC mRNA
CTD
PMID:34925699
NCBI chr15:63,696,177...63,717,042
Ensembl chr15:63,696,195...63,717,026
G
Gtpbp6
GTP binding protein 6 (putative)
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of GTPBP6 mRNA
CTD
PMID:34925699
NCBI chr 5:110,251,842...110,256,063
Ensembl chr 5:110,251,841...110,256,063
G
Gucy2c
guanylate cyclase 2c
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of GUCY2C mRNA
CTD
PMID:34925699
NCBI chr 6:136,674,282...136,758,740
Ensembl chr 6:136,674,282...136,758,763
G
H1f8
H1.8 linker histone
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of H1FOO mRNA
CTD
PMID:34925699
NCBI chr 6:115,921,892...115,927,203
Ensembl chr 6:115,921,899...115,927,197
G
H2ax
H2A.X variant histone
decreases expression
ISO
theaflavin-3,3'-digallate results in decreased expression of H2AX protein
CTD
PMID:34925699
NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374
G
H3c14
H3 clustered histone 14
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of H3C3 mRNA
CTD
PMID:34925699
NCBI chr 3:96,154,001...96,154,664
Ensembl chr 3:96,154,001...96,155,825
G
Hand1
heart and neural crest derivatives expressed 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of HAND1 mRNA
CTD
PMID:34925699
NCBI chr11:57,719,539...57,722,973
Ensembl chr11:57,719,531...57,723,644
G
Herpud1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of HERPUD1 mRNA
CTD
PMID:34925699
NCBI chr 8:95,113,057...95,121,999
Ensembl chr 8:95,113,066...95,122,005
G
Hes1
hes family bHLH transcription factor 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of HES1 mRNA
CTD
PMID:34925699
NCBI chr16:29,883,259...29,886,614
Ensembl chr16:29,883,202...29,886,614
G
Hey1
hairy/enhancer-of-split related with YRPW motif 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of HEY1 mRNA
CTD
PMID:34925699
NCBI chr 3:8,728,419...8,732,098
Ensembl chr 3:8,728,419...8,732,316
G
Hgd
homogentisate 1, 2-dioxygenase
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of HGD mRNA
CTD
PMID:34925699
NCBI chr16:37,400,104...37,452,388
Ensembl chr16:37,400,515...37,452,382
G
Hhatl
hedgehog acyltransferase-like
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of HHATL mRNA
CTD
PMID:34925699
NCBI chr 9:121,613,082...121,626,604
Ensembl chr 9:121,613,082...121,621,573
G
Hhipl2
hedgehog interacting protein-like 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of HHIPL2 mRNA
CTD
PMID:34925699
NCBI chr 1:183,195,395...183,217,962
Ensembl chr 1:183,199,147...183,217,717
G
Hif1a
hypoxia inducible factor 1, alpha subunit
decreases expression multiple interactions
ISO
theaflavin-3,3'-digallate results in decreased expression of HIF1A protein [Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased expression of HIF1A protein
CTD
PMID:34350509
NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304
G
Hmox1
heme oxygenase 1
multiple interactions increases expression
EXP ISO
theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in decreased expression of HMOX1 mRNA] theaflavin-3,3'-digallate results in increased expression of HMOX1 protein
CTD
PMID:32694992 PMID:35847580
NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
G
Hmx1
H6 homeobox 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of HMX1 mRNA
CTD
PMID:34925699
NCBI chr 5:35,546,124...35,557,629
Ensembl chr 5:35,546,452...35,557,074
G
Hormad1
HORMA domain containing 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of HORMAD1 mRNA
CTD
PMID:34925699
NCBI chr 3:95,466,988...95,495,174
Ensembl chr 3:95,466,988...95,494,982
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Hormad2
HORMA domain containing 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of HORMAD2 mRNA
CTD
PMID:34925699
NCBI chr11:4,295,801...4,391,215
Ensembl chr11:4,295,814...4,391,105
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Hoxa10
homeobox A10
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of HOXA10 mRNA
CTD
PMID:34925699
NCBI chr 6:52,208,177...52,217,658
Ensembl chr 6:52,208,177...52,217,834
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Hoxc10
homeobox C10
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of HOXC10 mRNA
CTD
PMID:34925699
NCBI chr15:102,875,231...102,880,333
Ensembl chr15:102,875,231...102,880,328
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Hs3st5
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of HS3ST5 mRNA
CTD
PMID:34925699
NCBI chr10:36,382,794...36,710,393
Ensembl chr10:36,382,810...36,710,393
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Hspa1a
heat shock protein 1A
multiple interactions decreases expression
ISO
[Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased expression of HSPA1A protein theaflavin-3,3'-digallate results in decreased expression of HSPA1A protein
CTD
PMID:34350509
NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132
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Hspa5
heat shock protein 5
multiple interactions decreases expression
ISO
[Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased expression of HSPA5 protein theaflavin-3,3'-digallate results in decreased expression of HSPA5 protein
CTD
PMID:34350509
NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
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Hspa8
heat shock protein 8
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of HSPA8 mRNA
CTD
PMID:34925699
NCBI chr 9:40,712,572...40,716,498
Ensembl chr 9:40,712,280...40,721,383
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Htr1d
5-hydroxytryptamine (serotonin) receptor 1D
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of HTR1D mRNA
CTD
PMID:34925699
NCBI chr 4:136,150,835...136,171,716
Ensembl chr 4:136,150,835...136,171,709
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Htr5a
5-hydroxytryptamine (serotonin) receptor 5A
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of HTR5A mRNA
CTD
PMID:34925699
NCBI chr 5:28,046,836...28,059,403
Ensembl chr 5:28,047,147...28,060,086
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Hus1b
HUS1 checkpoint clamp component B
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of HUS1B mRNA
CTD
PMID:34925699
NCBI chr13:31,130,559...31,131,744
Ensembl chr13:31,130,556...31,131,742
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Id3
inhibitor of DNA binding 3
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ID3 mRNA
CTD
PMID:34925699
NCBI chr 4:135,871,133...135,872,703
Ensembl chr 4:135,870,808...135,873,066
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Ier5l
immediate early response 5-like
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of IER5L mRNA
CTD
PMID:34925699
NCBI chr 2:30,362,643...30,364,211
Ensembl chr 2:30,361,549...30,364,231
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Igdcc3
immunoglobulin superfamily, DCC subclass, member 3
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of IGDCC3 mRNA
CTD
PMID:34925699
NCBI chr 9:65,048,404...65,094,313
Ensembl chr 9:65,048,471...65,093,154
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Igkv8-24
immunoglobulin kappa chain variable 8-24
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of EBLN1 mRNA
CTD
PMID:34925699
NCBI chr 6:70,193,842...70,194,405
Ensembl chr 6:70,193,842...70,194,405
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Il10
interleukin 10
affects expression multiple interactions
ISO EXP
theaflavin-3,3'-digallate affects the expression of IL10 mRNA theaflavin-3,3'-digallate results in increased expression of and results in increased secretion of IL10 protein
CTD
PMID:33833684 PMID:34925699
NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
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Il13
interleukin 13
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of IL13 mRNA
CTD
PMID:34925699
NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
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Il19
interleukin 19
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of IL19 mRNA
CTD
PMID:34925699
NCBI chr 1:130,860,393...130,873,194
Ensembl chr 1:130,860,393...130,867,852
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Il1b
interleukin 1 beta
multiple interactions decreases secretion
EXP ISO
theaflavin-3,3'-digallate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B mRNA]; theaflavin-3,3'-digallate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL1B protein] theaflavin-3,3'-digallate results in decreased secretion of IL1B protein theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of ACAN mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of ACAN protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of COL2A1 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of COL2A1 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of SOX9 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of SOX9 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased abundance of and results in increased secretion of Dinoprostone]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of ADAMTS5 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of ADAMTS5 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of IL6 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of MMP13 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of MMP3 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of NOS2 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of TNF mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of AKT1 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of and results in decreased expression of NFKBIA protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of MAPK1 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of MAPK3 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of RELA protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased secretion of IL1B protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased secretion of IL6 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased secretion of TNF protein]
CTD
PMID:27871911 PMID:30874838 PMID:33833684 PMID:35847580 PMID:37651426
NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
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Il2
interleukin 2
decreases expression
EXP
theaflavin-3,3'-digallate results in decreased expression of IL2 mRNA
CTD
PMID:34925699
NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
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Il5ra
interleukin 5 receptor, alpha
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of IL5RA mRNA
CTD
PMID:34925699
NCBI chr 6:106,687,336...106,725,998
Ensembl chr 6:106,687,318...106,725,998
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Il6
interleukin 6
multiple interactions decreases secretion
EXP ISO
theaflavin-3,3'-digallate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL6 protein] theaflavin-3,3'-digallate results in decreased secretion of IL6 protein theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of IL6 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased secretion of IL6 protein]
CTD
PMID:27871911 PMID:30874838 PMID:33833684 PMID:35847580 PMID:37651426
NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
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Inava
innate immunity activator
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of INAVA mRNA
CTD
PMID:34925699
NCBI chr 1:136,141,259...136,162,045
Ensembl chr 1:136,141,269...136,162,002
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Inhba
inhibin beta-A
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of INHBA mRNA
CTD
PMID:34925699
NCBI chr13:16,178,841...16,206,194
Ensembl chr13:16,186,436...16,206,206
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Insm2
insulinoma-associated 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of INSM2 mRNA
CTD
PMID:34925699
NCBI chr12:55,646,212...55,648,818
Ensembl chr12:55,646,212...55,648,871
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Insyn2b
inhibitory synaptic factor family member 2B
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of INSYN2B mRNA
CTD
PMID:34925699
NCBI chr11:34,264,822...34,372,642
Ensembl chr11:34,264,758...34,372,640
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Iqcn
IQ motif containing N
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of IQCN mRNA
CTD
PMID:34925699
NCBI chr 8:71,154,661...71,170,299
Ensembl chr 8:71,156,106...71,170,299
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Iqub
IQ motif and ubiquitin domain containing
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of IQUB mRNA
CTD
PMID:34925699
NCBI chr 6:24,444,864...24,515,066
Ensembl chr 6:24,444,864...24,515,066
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Irgc
immunity related GTPase cinema
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of IRGC mRNA
CTD
PMID:34925699
NCBI chr 7:24,131,344...24,145,107
Ensembl chr 7:24,131,347...24,151,722
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Itga2b
integrin alpha 2b
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ITGA2B mRNA
CTD
PMID:34925699
NCBI chr11:102,344,134...102,360,570
Ensembl chr11:102,344,123...102,360,948
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Itgb6
integrin beta 6
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ITGB6 mRNA
CTD
PMID:34925699
NCBI chr 2:60,428,636...60,553,005
Ensembl chr 2:60,428,636...60,552,987
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Izumo1r
IZUMO1 receptor, JUNO
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of IZUMO1R mRNA
CTD
PMID:34925699
NCBI chr 9:14,797,110...14,815,247
Ensembl chr 9:14,797,110...14,815,245
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Jag2
jagged 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of JAG2 mRNA
CTD
PMID:34925699
NCBI chr12:112,871,439...112,893,437
Ensembl chr12:112,871,439...112,893,396
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Jun
jun proto-oncogene
multiple interactions
EXP
theaflavin-3,3'-digallate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of JUN protein]
CTD
PMID:27871911
NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
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Kcne3
potassium voltage-gated channel, Isk-related subfamily, gene 3
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of KCNE3 mRNA
CTD
PMID:34925699
NCBI chr 7:99,825,714...99,834,076
Ensembl chr 7:99,825,709...99,834,076
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Kcnj6
potassium inwardly-rectifying channel, subfamily J, member 6
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of KCNJ6 mRNA
CTD
PMID:34925699
NCBI chr16:94,545,839...94,798,719
Ensembl chr16:94,549,495...94,798,560
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Kcnk7
potassium channel, subfamily K, member 7
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of KCNK7 mRNA
CTD
PMID:34925699
NCBI chr19:5,754,471...5,757,956
Ensembl chr19:5,754,395...5,757,137
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Kcnt1
potassium channel, subfamily T, member 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of KCNT1 mRNA
CTD
PMID:34925699
NCBI chr 2:25,753,807...25,808,285
Ensembl chr 2:25,753,746...25,808,285
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Kit
KIT proto-oncogene receptor tyrosine kinase
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of KIT mRNA
CTD
PMID:34925699
NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382
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Klk11
kallikrein related-peptidase 11
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of KLK11 mRNA
CTD
PMID:34925699
NCBI chr 7:43,424,041...43,428,687
Ensembl chr 7:43,424,028...43,428,687
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Klk14
kallikrein related-peptidase 14
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of KLK14 mRNA
CTD
PMID:34925699
NCBI chr 7:43,330,305...43,344,960
Ensembl chr 7:43,339,842...43,344,960
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Krt79
keratin 79
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of KRT79 mRNA
CTD
PMID:34925699
NCBI chr15:101,837,767...101,848,759
Ensembl chr15:101,837,767...101,848,759
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Lair1
leukocyte-associated Ig-like receptor 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of LAIR1 mRNA
CTD
PMID:34925699
NCBI chr 7:4,010,072...4,076,566
Ensembl chr 7:4,006,401...4,066,178
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Lat2
linker for activation of T cells family, member 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of LAT2 mRNA
CTD
PMID:34925699
NCBI chr 5:134,628,957...134,648,637
Ensembl chr 5:134,628,876...134,643,879
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Ldb2
LIM domain binding 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of LDB2 mRNA
CTD
PMID:34925699
NCBI chr 5:44,593,292...44,957,466
Ensembl chr 5:44,629,474...44,957,022
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Ldhal6b
lactate dehydrogenase A-like 6B
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of LDHAL6B mRNA
CTD
PMID:34925699
NCBI chr17:5,467,598...5,469,042
Ensembl chr17:5,467,598...5,469,042
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Lep
leptin
multiple interactions
EXP
theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of ACADM mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of CYP1A2 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of CYP2C70 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of CYP4F14 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of DHCR7 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of EBP mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of ELOVL1 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of FABP4 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of FADS1 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of FDFT1 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of LPL mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of PLIN4 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of PPARD mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of SCD1 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of TECR mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of TM7SF2 mRNA]
CTD
PMID:36105184
NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
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Lgr5
leucine rich repeat containing G protein coupled receptor 5
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of LGR5 mRNA
CTD
PMID:34925699
NCBI chr10:115,286,219...115,423,685
Ensembl chr10:115,286,216...115,423,685
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Lman1l
lectin, mannose-binding 1 like
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of LMAN1L mRNA
CTD
PMID:34925699
NCBI chr 9:57,514,080...57,528,057
Ensembl chr 9:57,514,368...57,528,057
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Lpl
lipoprotein lipase
multiple interactions
EXP
theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of LPL mRNA]
CTD
PMID:36105184
NCBI chr 8:69,333,207...69,359,584
Ensembl chr 8:69,333,143...69,360,100
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Lrp1b
low density lipoprotein-related protein 1B
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of LRP1B mRNA
CTD
PMID:34925699
NCBI chr 2:40,485,302...42,543,747
Ensembl chr 2:40,485,258...42,543,636
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Lrrc18
leucine rich repeat containing 18
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of LRRC18 mRNA
CTD
PMID:34925699
NCBI chr14:32,713,339...32,737,257
Ensembl chr14:32,713,339...32,737,248
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Lrrc66
leucine rich repeat containing 66
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of LRRC66 mRNA
CTD
PMID:34925699
NCBI chr 5:73,763,985...73,789,771
Ensembl chr 5:73,763,985...73,789,869
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Lsmem1
leucine-rich single-pass membrane protein 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of LSMEM1 mRNA
CTD
PMID:34925699
NCBI chr12:40,226,385...40,249,314
Ensembl chr12:40,225,492...40,249,489
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Ly9
lymphocyte antigen 9
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of LY9 mRNA
CTD
PMID:34925699
NCBI chr 1:171,416,172...171,434,917
Ensembl chr 1:171,416,192...171,434,978
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Mab21l3
mab-21-like 3
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of MAB21L3 mRNA
CTD
PMID:34925699
NCBI chr 3:101,720,392...101,743,601
Ensembl chr 3:101,720,392...101,756,275
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Mafb
MAF bZIP transcription factor B
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of MAFB mRNA
CTD
PMID:34925699
NCBI chr 2:160,205,597...160,208,985
Ensembl chr 2:160,205,623...160,208,985
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Malrd1
MAM and LDL receptor class A domain containing 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of MALRD1 mRNA
CTD
PMID:34925699
NCBI chr 2:15,531,290...16,260,368
Ensembl chr 2:15,531,290...16,260,366
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Map1lc3b
microtubule-associated protein 1 light chain 3 beta
decreases expression multiple interactions
ISO
theaflavin-3,3'-digallate results in decreased expression of MAP1LC3B protein [Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased expression of MAP1LC3B protein
CTD
PMID:34350509
NCBI chr 8:122,317,177...122,325,499
Ensembl chr 8:122,317,100...122,325,499
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Map2k1
mitogen-activated protein kinase kinase 1
decreases expression
ISO
theaflavin-3,3'-digallate results in decreased expression of MAP2K1 mRNA; theaflavin-3,3'-digallate results in decreased expression of MAP2K1 protein
CTD
PMID:32964953
NCBI chr 9:64,093,066...64,160,887
Ensembl chr 9:64,093,052...64,160,913
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Map2k2
mitogen-activated protein kinase kinase 2
decreases expression
ISO
theaflavin-3,3'-digallate results in decreased expression of MAP2K2 mRNA; theaflavin-3,3'-digallate results in decreased expression of MAP2K2 protein
CTD
PMID:32964953
NCBI chr10:80,941,749...80,960,531
Ensembl chr10:80,941,749...80,969,809
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Mapk1
mitogen-activated protein kinase 1
multiple interactions decreases phosphorylation decreases expression
ISO EXP
theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of MAPK1 protein]; theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in increased phosphorylation of MAPK1 protein] theaflavin-3,3'-digallate results in decreased phosphorylation of MAPK1 protein theaflavin-3,3'-digallate results in decreased expression of MAPK1 mRNA; theaflavin-3,3'-digallate results in decreased expression of MAPK1 protein theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased phosphorylation of MAPK1 protein]
CTD
PMID:16353237 PMID:30874838 PMID:32694992 PMID:32964953 PMID:33833684 PMID:35847580 PMID:35903325 More...
NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
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Mapk3
mitogen-activated protein kinase 3
multiple interactions decreases phosphorylation decreases expression
ISO EXP
theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of MAPK3 protein]; theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in increased phosphorylation of MAPK3 protein] theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased phosphorylation of MAPK3 protein] theaflavin-3,3'-digallate results in decreased phosphorylation of MAPK3 protein theaflavin-3,3'-digallate results in decreased expression of MAPK3 mRNA; theaflavin-3,3'-digallate results in decreased expression of MAPK3 protein
CTD
PMID:16353237 PMID:30874838 PMID:32694992 PMID:32964953 PMID:33833684 PMID:35847580 PMID:35903325 More...
NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
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Mapk8
mitogen-activated protein kinase 8
decreases phosphorylation multiple interactions
EXP ISO
theaflavin-3,3'-digallate results in decreased phosphorylation of MAPK8 protein theaflavin-3,3'-digallate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK8 protein] theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in increased phosphorylation of MAPK8 protein]
CTD
PMID:27871911 PMID:32694992 PMID:35903325
NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115
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Mapk9
mitogen-activated protein kinase 9
decreases phosphorylation
EXP
theaflavin-3,3'-digallate results in decreased phosphorylation of MAPK9 protein
CTD
PMID:30874838
NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248
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Matn4
matrilin 4
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of MATN4 mRNA
CTD
PMID:34925699
NCBI chr 2:164,231,313...164,247,080
Ensembl chr 2:164,231,313...164,247,080
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Mep1b
meprin 1 beta
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of MEP1B mRNA
CTD
PMID:34925699
NCBI chr18:21,205,401...21,233,256
Ensembl chr18:21,194,980...21,233,256
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Mgam
maltase-glucoamylase
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of MGAM mRNA
CTD
PMID:34925699
NCBI chr 6:40,605,765...40,746,057
Ensembl chr 6:40,605,765...40,746,057
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Mia
MIA SH3 domain containing
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of MIA mRNA
CTD
PMID:34925699
NCBI chr 7:26,879,166...26,880,574
Ensembl chr 7:26,879,167...26,880,582
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Mkx
mohawk homeobox
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of MKX mRNA
CTD
PMID:34925699
NCBI chr18:6,934,966...7,004,779
Ensembl chr18:6,934,518...7,004,780
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Mmp13
matrix metallopeptidase 13
multiple interactions
ISO
theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of MMP13 protein]
CTD
PMID:35847580
NCBI chr 9:7,272,514...7,283,333
Ensembl chr 9:7,272,514...7,283,331
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Mmp17
matrix metallopeptidase 17
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of MMP17 mRNA
CTD
PMID:34925699
NCBI chr 5:129,661,215...129,688,163
Ensembl chr 5:129,661,233...129,688,163
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Mmp1b
matrix metallopeptidase 1b (interstitial collagenase)
decreases expression
EXP
theaflavin-3,3'-digallate results in decreased expression of MMP1 protein
CTD
PMID:30874838
NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
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Mmp2
matrix metallopeptidase 2
decreases expression
EXP
theaflavin-3,3'-digallate results in decreased expression of MMP2 protein
CTD
PMID:30874838
NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
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Mmp3
matrix metallopeptidase 3
multiple interactions decreases expression
ISO EXP
theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of MMP3 protein] theaflavin-3,3'-digallate results in decreased expression of MMP3 protein
CTD
PMID:30874838 PMID:35847580
NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975
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Mmp9
matrix metallopeptidase 9
multiple interactions
EXP
theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in increased expression of MMP9 mRNA]
CTD
PMID:32694992
NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
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Morn3
MORN repeat containing 3
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of MORN3 mRNA
CTD
PMID:34925699
NCBI chr 5:123,171,462...123,185,099
Ensembl chr 5:123,173,832...123,185,079
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Mos
Moloney sarcoma oncogene
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of MOS mRNA
CTD
PMID:34925699
NCBI chr 4:3,870,658...3,872,105
Ensembl chr 4:3,870,657...3,872,105
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Mpl
myeloproliferative leukemia virus oncogene
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of MPL mRNA
CTD
PMID:34925699
NCBI chr 4:118,299,609...118,314,771
Ensembl chr 4:118,299,612...118,314,710
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Mpzl2
myelin protein zero-like 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of MPZL2 mRNA
CTD
PMID:34925699
NCBI chr 9:44,951,595...44,965,341
Ensembl chr 9:44,951,097...44,965,313
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Mrap2
melanocortin 2 receptor accessory protein 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of MRAP2 mRNA
CTD
PMID:34925699
NCBI chr 9:87,026,293...87,066,104
Ensembl chr 9:87,026,359...87,066,098
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Mroh2b
maestro heat-like repeat family member 2B
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of MROH2B mRNA
CTD
PMID:34925699
NCBI chr15:4,927,697...4,991,689
Ensembl chr15:4,928,219...4,991,687
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Ms4a5
membrane-spanning 4-domains, subfamily A, member 5
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of MS4A5 mRNA
CTD
PMID:34925699
NCBI chr19:11,251,514...11,261,259
Ensembl chr19:11,250,602...11,261,237
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Mtfr2
mitochondrial fission regulator 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of MTFR2 mRNA
CTD
PMID:34925699
NCBI chr10:20,223,491...20,237,415
Ensembl chr10:20,223,516...20,237,050
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Mtor
mechanistic target of rapamycin kinase
multiple interactions
ISO
theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in increased phosphorylation of MTOR protein]
CTD
PMID:35903325
NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140
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Muc13
mucin 13, epithelial transmembrane
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of MUC13 mRNA
CTD
PMID:34925699
NCBI chr16:33,614,407...33,640,299
Ensembl chr16:33,614,407...33,640,304
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Muc5ac
mucin 5, subtypes A and C, tracheobronchial/gastric
multiple interactions
ISO
[theaflavin co-treated with theaflavine gallate co-treated with theaflavin-3,3'-digallate] inhibits the reaction [Tobacco Smoke Pollution results in increased expression of and results in increased phosphorylation of MUC5AC protein]; [theaflavin co-treated with theaflavine gallate co-treated with theaflavin-3,3'-digallate] inhibits the reaction [Tobacco Smoke Pollution results in increased expression of MUC5AC mRNA]
CTD
PMID:21475988
NCBI chr 7:141,342,695...141,372,964
Ensembl chr 7:141,342,709...141,372,968
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Muc5b
mucin 5, subtype B, tracheobronchial
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of MUC5B mRNA
CTD
PMID:34925699
NCBI chr 7:141,392,796...141,426,826
Ensembl chr 7:141,392,807...141,426,821
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Myadml2
myeloid-associated differentiation marker-like 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of MYADML2 mRNA
CTD
PMID:34925699
NCBI chr11:120,536,857...120,539,188
Ensembl chr11:120,536,857...120,538,984
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Mybphl
myosin binding protein H-like
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of MYBPHL mRNA
CTD
PMID:34925699
NCBI chr 3:108,272,227...108,287,373
Ensembl chr 3:108,272,227...108,287,373
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Myh11
myosin, heavy polypeptide 11, smooth muscle
multiple interactions
ISO
theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in decreased expression of MYH11 protein]
CTD
PMID:35903325
NCBI chr16:14,012,392...14,109,227
Ensembl chr16:14,012,399...14,109,236
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Mylk3
myosin light chain kinase 3
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of MYLK3 mRNA
CTD
PMID:34925699
NCBI chr 8:86,050,933...86,112,969
Ensembl chr 8:86,050,932...86,112,974
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Myo1a
myosin IA
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of MYO1A mRNA
CTD
PMID:34925699
NCBI chr10:127,539,306...127,556,809
Ensembl chr10:127,541,039...127,556,809
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Myo1f
myosin IF
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of MYO1F mRNA
CTD
PMID:34925699
NCBI chr17:33,774,681...33,826,738
Ensembl chr17:33,774,681...33,826,738
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Myod1
myogenic differentiation 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of MYOD1 mRNA
CTD
PMID:34925699
NCBI chr 7:46,025,898...46,028,516
Ensembl chr 7:46,025,898...46,028,523
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Nalf2
NALCN channel auxiliary factor 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of NALF2 mRNA
CTD
PMID:34925699
NCBI chr X:98,863,770...98,892,395
Ensembl chr X:98,864,627...98,892,396
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Ncf4
neutrophil cytosolic factor 4
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of NCF4 mRNA
CTD
PMID:34925699
NCBI chr15:78,128,324...78,146,782
Ensembl chr15:78,129,001...78,146,780
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Nckap1l
NCK associated protein 1 like
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of NCKAP1L mRNA
CTD
PMID:34925699
NCBI chr15:103,362,219...103,411,288
Ensembl chr15:103,362,221...103,407,237
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Neurog2
neurogenin 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of NEUROG2 mRNA
CTD
PMID:34925699
NCBI chr 3:127,426,382...127,429,285
Ensembl chr 3:127,426,784...127,429,280
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Nfatc3
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3
multiple interactions
ISO
theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in decreased phosphorylation of NFATC3 protein]
CTD
PMID:35406003
NCBI chr 8:106,785,450...106,857,169
Ensembl chr 8:106,785,472...106,857,169
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Nfe2l2
nuclear factor, erythroid derived 2, like 2
multiple interactions increases expression
ISO EXP
theaflavin-3,3'-digallate results in increased expression of and affects the localization of NFE2L2 protein theaflavin-3,3'-digallate results in increased expression of NFE2L2 protein [theaflavin-3,3'-digallate results in increased expression of NFE2L2 protein] inhibits the reaction [TNFSF11 protein results in increased abundance of Reactive Oxygen Species]; [theaflavin-3,3'-digallate results in increased expression of NFE2L2 protein] which results in decreased abundance of Reactive Oxygen Species; theaflavin-3,3'-digallate inhibits the reaction [Galactose results in decreased expression of NFE2L2 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in decreased expression of NFE2L2 mRNA]; theaflavin-3,3'-digallate results in increased expression of and affects the localization of NFE2L2 protein
CTD
PMID:32694992 PMID:35847580 PMID:36638877
NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
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Nfkbia
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
multiple interactions
ISO
theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of and results in decreased expression of NFKBIA protein]
CTD
PMID:35847580
NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
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Nkain3
Na+/K+ transporting ATPase interacting 3
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of NKAIN3 mRNA
CTD
PMID:34925699
NCBI chr 4:20,111,029...20,779,990
Ensembl chr 4:20,118,874...20,778,866
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Nkx3-2
NK3 homeobox 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of NKX3-2 mRNA
CTD
PMID:34925699
NCBI chr 5:41,918,826...41,921,563
Ensembl chr 5:41,918,826...41,921,844
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Nlrp4c
NLR family, pyrin domain containing 4C
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of NLRP4 mRNA
CTD
PMID:34925699
NCBI chr 7:6,048,160...6,108,148
Ensembl chr 7:6,048,160...6,108,149
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Nlrp5
NLR family, pyrin domain containing 5
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of NLRP5 mRNA
CTD
PMID:34925699
NCBI chr 7:23,085,314...23,141,348
Ensembl chr 7:23,085,314...23,141,347
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Nos2
nitric oxide synthase 2, inducible
multiple interactions
ISO
theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of NOS2 protein]
CTD
PMID:35847580
NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
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Notum
notum palmitoleoyl-protein carboxylesterase
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of NOTUM mRNA
CTD
PMID:34925699
NCBI chr11:120,544,614...120,552,019
Ensembl chr11:120,544,614...120,552,001
G
Nova2
NOVA alternative splicing regulator 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of NOVA2 mRNA
CTD
PMID:34925699
NCBI chr 7:18,659,319...18,699,244
Ensembl chr 7:18,659,813...18,699,244
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Nppa
natriuretic peptide type A
multiple interactions
ISO
theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in increased expression of ANP mRNA]
CTD
PMID:35406003
NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536
G
Nppb
natriuretic peptide type B
multiple interactions
ISO
theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in increased expression of BNP mRNA]
CTD
PMID:35406003
NCBI chr 4:148,070,264...148,071,662
Ensembl chr 4:148,070,245...148,071,662
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Nr4a2
nuclear receptor subfamily 4, group A, member 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of NR4A2 mRNA
CTD
PMID:34925699
NCBI chr 2:56,996,845...57,014,152
Ensembl chr 2:56,996,842...57,014,015
G
Nrg1
neuregulin 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of NRG1 mRNA
CTD
PMID:34925699
NCBI chr 8:32,299,493...33,381,858
Ensembl chr 8:32,304,579...33,374,825 Ensembl chr 8:32,304,579...33,374,825
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Nusap1
nucleolar and spindle associated protein 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of NUSAP1 mRNA
CTD
PMID:34925699
NCBI chr 2:119,449,205...119,480,646
Ensembl chr 2:119,448,779...119,481,725
G
Nxf2
nuclear RNA export factor 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of NXF5 mRNA
CTD
PMID:34925699
NCBI chr X:133,845,275...133,865,503
Ensembl chr X:133,845,275...133,865,503
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Olig1
oligodendrocyte transcription factor 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of OLIG1 mRNA
CTD
PMID:34925699
NCBI chr16:91,066,657...91,068,827
Ensembl chr16:91,066,660...91,068,821
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Omg
oligodendrocyte myelin glycoprotein
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of OMG mRNA
CTD
PMID:34925699
NCBI chr11:79,391,808...79,394,908
Ensembl chr11:79,391,808...79,394,910
G
Opn1sw
opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of OPN1SW mRNA
CTD
PMID:34925699
NCBI chr 6:29,376,670...29,380,512
Ensembl chr 6:29,376,670...29,388,467
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Or2a25
olfactory receptor family 2 subfamily A member 25
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of OR2A25 mRNA
CTD
PMID:34925699
NCBI chr 6:42,888,459...42,889,391
Ensembl chr 6:42,885,812...42,891,207
G
Or2k2
olfactory receptor family 2 subfamily K member 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of OR2K2 mRNA
CTD
PMID:34925699
NCBI chr 4:58,784,779...58,785,720
Ensembl chr 4:58,782,704...58,787,716
G
Or3a1d
olfactory receptor family 3 subfamily A member 1D
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of OR3A3 mRNA
CTD
PMID:34925699
NCBI chr11:74,237,450...74,238,498
Ensembl chr11:74,235,955...74,243,476
G
Or51i1
olfactory receptor family 51 subfamily I member 1D
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of OR51I1 mRNA
CTD
PMID:34925699
NCBI chr 7:103,670,579...103,671,523
Ensembl chr 7:103,667,893...103,674,780
G
Or5b99
olfactory receptor family 5 subfamily B member 99
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of OR5B2 mRNA
CTD
PMID:34925699
NCBI chr19:12,976,352...12,977,284
Ensembl chr19:12,972,378...12,977,781
G
Orm2
orosomucoid 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ORM2 mRNA
CTD
PMID:34925699
NCBI chr 4:63,280,543...63,284,114
Ensembl chr 4:63,280,686...63,284,115
G
Otol1
otolin 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of OTOL1 mRNA
CTD
PMID:34925699
NCBI chr 3:69,914,946...69,936,041
Ensembl chr 3:69,914,946...69,936,041
G
Otor
otoraplin
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of OTOR mRNA
CTD
PMID:34925699
NCBI chr 2:142,920,313...142,923,633
Ensembl chr 2:142,920,393...142,923,633
G
Otp
orthopedia homeobox
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of OTP mRNA
CTD
PMID:34925699
NCBI chr13:95,012,144...95,021,633
Ensembl chr13:95,012,110...95,021,638
G
Otx2
orthodenticle homeobox 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of OTX2 mRNA
CTD
PMID:34925699
NCBI chr14:48,894,238...48,905,101
Ensembl chr14:48,895,134...48,911,276
G
Padi6
peptidyl arginine deiminase, type VI
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PADI6 mRNA
CTD
PMID:34925699
NCBI chr 4:140,454,666...140,469,954
Ensembl chr 4:140,454,666...140,469,954
G
Parp1
poly (ADP-ribose) polymerase family, member 1
increases cleavage
ISO
theaflavin-3,3'-digallate results in increased cleavage of PARP1 protein
CTD
PMID:30769778
NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
G
Pate1
prostate and testis expressed 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PATE1 mRNA
CTD
PMID:34925699
NCBI chr 9:35,596,182...35,598,686
Ensembl chr 9:35,596,375...35,598,686
G
Pax3
paired box 3
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PAX3 mRNA
CTD
PMID:34925699
NCBI chr 1:78,077,904...78,173,773
Ensembl chr 1:78,077,904...78,173,771
G
Pbx4
pre B cell leukemia homeobox 4
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PBX4 mRNA
CTD
PMID:34925699
NCBI chr 8:70,285,127...70,324,942
Ensembl chr 8:70,285,141...70,324,942
G
Pcdha5
protocadherin alpha 5
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PCDHA5 mRNA
CTD
PMID:34925699
NCBI chr18:37,093,329...37,320,716
Ensembl chr18:37,093,493...37,320,710
G
Pcp4l1
Purkinje cell protein 4-like 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PCP4L1 mRNA
CTD
PMID:34925699
NCBI chr 1:171,000,833...171,023,837
Ensembl chr 1:171,000,831...171,023,837
G
Pcsk2
proprotein convertase subtilisin/kexin type 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PCSK2 mRNA
CTD
PMID:34925699
NCBI chr 2:143,388,053...143,658,204
Ensembl chr 2:143,388,076...143,658,205
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Pde2a
phosphodiesterase 2A, cGMP-stimulated
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PDE2A mRNA
CTD
PMID:34925699
NCBI chr 7:101,070,905...101,162,026
Ensembl chr 7:101,060,093...101,162,026 Ensembl chr 7:101,060,093...101,162,026
G
Pde3a
phosphodiesterase 3A, cGMP inhibited
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PDE3A mRNA
CTD
PMID:34925699
NCBI chr 6:141,194,995...141,452,588
Ensembl chr 6:141,194,995...141,453,174
G
Pdgfrb
platelet derived growth factor receptor, beta polypeptide
multiple interactions
ISO
theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in increased phosphorylation of PDGFRB protein]
CTD
PMID:35903325
NCBI chr18:61,178,194...61,218,139
Ensembl chr18:61,178,222...61,218,133
G
Pex5l
peroxisomal biogenesis factor 5-like
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PEX5L mRNA
CTD
PMID:34925699
NCBI chr 3:33,002,075...33,197,470
Ensembl chr 3:33,003,557...33,197,396
G
Pgcka1
PDCD10 and GCKIII kinases associated 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PGCKA1 mRNA
CTD
PMID:34925699
NCBI chr 5:63,969,833...64,056,968
Ensembl chr 5:63,969,706...64,056,968
G
Phospho1
phosphatase, orphan 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PHOSPHO1 mRNA
CTD
PMID:34925699
NCBI chr11:95,715,326...95,722,966
Ensembl chr11:95,715,325...95,722,966
G
Pkd1l1
polycystic kidney disease 1 like 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PKD1L1 mRNA
CTD
PMID:34925699
NCBI chr11:8,782,025...8,924,365
Ensembl chr11:8,776,708...8,938,709
G
Pkd1l3
polycystic kidney disease 1 like 3
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PKD1L3 mRNA
CTD
PMID:34925699
NCBI chr 8:110,340,828...110,399,305
Ensembl chr 8:110,341,149...110,401,018
G
Pkdrej
polycystin (PKD) family receptor for egg jelly
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PKDREJ mRNA
CTD
PMID:34925699
NCBI chr15:85,698,877...85,705,934
Ensembl chr15:85,698,871...85,705,935
G
Pla2g12b
phospholipase A2, group XIIB
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PLA2G12B mRNA
CTD
PMID:34925699
NCBI chr10:59,239,242...59,257,798
Ensembl chr10:59,239,482...59,257,798
G
Pla2g2f
phospholipase A2, group IIF
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PLA2G2F mRNA
CTD
PMID:34925699
NCBI chr 4:138,477,842...138,484,932
Ensembl chr 4:138,477,844...138,484,937
G
Plcg1
phospholipase C, gamma 1
multiple interactions
ISO
theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in increased phosphorylation of PLCG1 protein]
CTD
PMID:35903325
NCBI chr 2:160,573,230...160,617,680
Ensembl chr 2:160,573,220...160,617,680
G
Plekha6
pleckstrin homology domain containing, family A member 6
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PLEKHA6 mRNA
CTD
PMID:34925699
NCBI chr 1:133,089,770...133,231,173
Ensembl chr 1:133,091,948...133,231,173
G
Plin1
perilipin 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PLIN1 mRNA
CTD
PMID:34925699
NCBI chr 7:79,370,912...79,382,652
Ensembl chr 7:79,369,966...79,382,651
G
Plin4
perilipin 4
multiple interactions
EXP
theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of PLIN4 mRNA]
CTD
PMID:36105184
NCBI chr17:56,407,587...56,416,947
Ensembl chr17:56,407,591...56,416,803
G
Plpp2
phospholipid phosphatase 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PLPP2 mRNA
CTD
PMID:34925699
NCBI chr10:79,362,258...79,369,621
Ensembl chr10:79,362,264...79,369,630
G
Pmp2
peripheral myelin protein 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PMP2 mRNA
CTD
PMID:34925699
NCBI chr 3:10,244,911...10,248,945
Ensembl chr 3:10,244,911...10,248,989
G
Ppard
peroxisome proliferator activator receptor delta
multiple interactions
EXP
theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of PPARD mRNA]
CTD
PMID:36105184
NCBI chr17:28,451,715...28,520,446
Ensembl chr17:28,451,674...28,520,448
G
Ppef2
protein phosphatase, EF hand calcium-binding domain 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PPEF2 mRNA
CTD
PMID:34925699
NCBI chr 5:92,374,109...92,404,759
Ensembl chr 5:92,374,538...92,404,137
G
Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
multiple interactions
ISO
theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in increased expression of PPP3CA protein]
CTD
PMID:35406003
NCBI chr 3:136,375,778...136,643,488
Ensembl chr 3:136,375,885...136,643,488
G
Prap1
proline-rich acidic protein 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PRAP1 mRNA
CTD
PMID:34925699
NCBI chr 7:139,673,309...139,677,116
Ensembl chr 7:139,673,308...139,677,113
G
Prdx2
peroxiredoxin 2
multiple interactions
EXP
theaflavin-3,3'-digallate inhibits the reaction [Galactose results in decreased expression of PRDX2 mRNA]
CTD
PMID:36638877
NCBI chr 8:85,696,251...85,701,440
Ensembl chr 8:85,696,216...85,701,463
G
Prkag3
protein kinase, AMP-activated, gamma 3 non-catalytic subunit
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PRKAG3 mRNA
CTD
PMID:34925699
NCBI chr 1:74,778,062...74,788,623
Ensembl chr 1:74,778,081...74,788,380
G
Prokr1
prokineticin receptor 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PROKR1 mRNA
CTD
PMID:34925699
NCBI chr 6:87,555,568...87,567,741
Ensembl chr 6:87,555,573...87,567,725
G
Proz
protein Z, vitamin K-dependent plasma glycoprotein
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PROZ mRNA
CTD
PMID:34925699
NCBI chr 8:13,110,583...13,126,026
Ensembl chr 8:13,110,914...13,126,026
G
Ptcra
pre T cell antigen receptor alpha
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PTCRA mRNA
CTD
PMID:34925699
NCBI chr17:47,066,589...47,074,659
Ensembl chr17:47,066,589...47,074,638
G
Ptgdr2
prostaglandin D2 receptor 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PTGDR2 mRNA
CTD
PMID:34925699
NCBI chr19:10,901,883...10,919,875
Ensembl chr19:10,914,524...10,919,875
G
Ptgir
prostaglandin I receptor (IP)
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PTGIR mRNA
CTD
PMID:34925699
NCBI chr 7:16,640,442...16,644,828
Ensembl chr 7:16,640,415...16,644,830
G
Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions
ISO
theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]
CTD
PMID:35847580
NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
G
Pygm
muscle glycogen phosphorylase
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PYGM mRNA
CTD
PMID:34925699
NCBI chr19:6,434,438...6,448,494
Ensembl chr19:6,434,429...6,448,489
G
Pyy
peptide YY
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of PYY mRNA
CTD
PMID:34925699
NCBI chr11:101,997,502...101,998,658
Ensembl chr11:101,997,502...101,998,658
G
Rab39
RAB39, member RAS oncogene family
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of RAB39A mRNA
CTD
PMID:34925699
NCBI chr 9:53,595,410...53,617,532
Ensembl chr 9:53,595,410...53,617,532
G
Rab44
RAB44, member RAS oncogene family
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of RAB44 mRNA
CTD
PMID:34925699
NCBI chr17:29,333,102...29,367,966
Ensembl chr17:29,333,119...29,367,954
G
Rb1
RB transcriptional corepressor 1
multiple interactions
ISO
CDKN1B promotes the reaction [theaflavin-3,3'-digallate results in decreased expression of and results in decreased phosphorylation of RB1 protein]; theaflavin-3,3'-digallate results in decreased expression of and results in decreased phosphorylation of RB1 protein
CTD
PMID:30769778
NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262
G
Rbfox3
RNA binding protein, fox-1 homolog (C. elegans) 3
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of RBFOX3 mRNA
CTD
PMID:34925699
NCBI chr11:118,380,586...118,802,423
Ensembl chr11:118,380,588...118,802,423
G
Rbp7
retinol binding protein 7, cellular
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of RBP7 mRNA
CTD
PMID:34925699
NCBI chr 4:149,534,144...149,550,919
Ensembl chr 4:149,534,144...149,539,435
G
Rcan2
regulator of calcineurin 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of RCAN2 mRNA
CTD
PMID:34925699
NCBI chr17:44,112,243...44,350,407
Ensembl chr17:44,112,242...44,350,407
G
Rcvrn
recoverin
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of RCVRN mRNA
CTD
PMID:34925699
NCBI chr11:67,586,152...67,594,181
Ensembl chr11:67,586,152...67,594,159
G
Rd3
retinal degeneration 3
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of RD3 mRNA
CTD
PMID:34925699
NCBI chr 1:191,688,574...191,725,497
Ensembl chr 1:191,709,331...191,720,244
G
Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
multiple interactions
ISO EXP
theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of RELA protein] theaflavin-3,3'-digallate inhibits the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of RELA protein]; theaflavin-3,3'-digallate results in decreased expression of and affects the localization of RELA protein
CTD
PMID:27871911 PMID:30874838 PMID:35847580
NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
G
Retn
resistin
multiple interactions
EXP
theaflavin-3,3'-digallate inhibits the reaction [Methylmercury Compounds results in increased secretion of RETN protein]
CTD
PMID:31195622
NCBI chr 8:3,705,770...3,709,818
Ensembl chr 8:3,705,770...3,710,110
G
Rfx6
regulatory factor X, 6
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of RFX6 mRNA
CTD
PMID:34925699
NCBI chr10:51,553,856...51,606,525
Ensembl chr10:51,553,852...51,606,528
G
Rgs18
regulator of G-protein signaling 18
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of RGS18 mRNA
CTD
PMID:34925699
NCBI chr 1:144,628,430...144,651,165
Ensembl chr 1:144,628,421...144,651,173
G
Rhoh
ras homolog family member H
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of RHOH mRNA
CTD
PMID:34925699
NCBI chr 5:66,018,092...66,054,043
Ensembl chr 5:66,018,556...66,054,043
G
Rnf152
ring finger protein 152
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of RNF152 mRNA
CTD
PMID:34925699
NCBI chr 1:105,204,642...105,284,665
Ensembl chr 1:105,204,639...105,284,435
G
Rspo1
R-spondin 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of RSPO1 mRNA
CTD
PMID:34925699
NCBI chr 4:124,880,197...124,902,895
Ensembl chr 4:124,880,223...124,902,892
G
Rspo2
R-spondin 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of RSPO2 mRNA
CTD
PMID:34925699
NCBI chr15:42,884,184...43,034,990
Ensembl chr15:42,884,190...43,034,222
G
Runx2
runt related transcription factor 2
multiple interactions increases expression
EXP
theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased expression of RUNX2 protein] theaflavin-3,3'-digallate results in increased expression of RUNX2 protein
CTD
PMID:33833684
NCBI chr17:44,806,873...45,125,518
Ensembl chr17:44,806,874...45,125,684
G
Scd1
stearoyl-Coenzyme A desaturase 1
multiple interactions
EXP
theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of SCD1 mRNA]
CTD
PMID:36105184
NCBI chr19:44,382,889...44,396,148
Ensembl chr19:44,382,894...44,396,318
G
Scnn1b
sodium channel, nonvoltage-gated 1 beta
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SCNN1B mRNA
CTD
PMID:34925699
NCBI chr 7:121,464,261...121,517,951
Ensembl chr 7:121,464,261...121,517,737
G
Scx
scleraxis scleraxis bHLH transcription factor
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SCX mRNA
CTD
PMID:34925699
NCBI chr15:76,341,594...76,343,668
Ensembl chr15:76,341,652...76,343,658
G
Sdr42e1
short chain dehydrogenase/reductase family 42E, member 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SDR42E1 mRNA
CTD
PMID:34925699
NCBI chr 8:118,388,138...118,400,428
Ensembl chr 8:118,388,138...118,400,428
G
Selp
selectin, platelet
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SELP mRNA
CTD
PMID:34925699
NCBI chr 1:163,942,833...163,977,595
Ensembl chr 1:163,942,833...163,977,595
G
Selplg
selectin, platelet (p-selectin) ligand
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SELPLG mRNA
CTD
PMID:34925699
NCBI chr 5:113,955,859...113,970,576
Ensembl chr 5:113,956,597...113,970,705
G
Serinc4
serine incorporator 4
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SERINC4 mRNA
CTD
PMID:34925699
NCBI chr 2:121,281,658...121,287,245
Ensembl chr 2:121,269,540...121,287,262
G
Serpina6
serine (or cysteine) peptidase inhibitor, clade A, member 6
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SERPINA6 mRNA
CTD
PMID:34925699
NCBI chr12:103,612,889...103,623,477
Ensembl chr12:103,612,889...103,623,471
G
Serpinb10
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SERPINB10 mRNA
CTD
PMID:34925699
NCBI chr 1:107,456,724...107,488,469
Ensembl chr 1:107,456,757...107,477,001
G
Serpinb5
serine (or cysteine) peptidase inhibitor, clade B, member 5
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SERPINB5 mRNA
CTD
PMID:34925699
NCBI chr 1:106,788,905...106,811,078
Ensembl chr 1:106,788,903...106,811,078
G
Serpinc1
serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SERPINC1 mRNA
CTD
PMID:34925699
NCBI chr 1:160,806,153...160,830,113
Ensembl chr 1:160,806,155...160,833,433
G
Sfn
stratifin
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SFN mRNA
CTD
PMID:34925699
NCBI chr 4:133,327,867...133,329,163
Ensembl chr 4:133,327,867...133,329,479
G
Sh2d4b
SH2 domain containing 4B
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SH2D4B mRNA
CTD
PMID:34925699
NCBI chr14:40,533,478...40,624,294
Ensembl chr14:40,535,746...40,615,223
G
Sh2d7
SH2 domain containing 7
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SH2D7 mRNA
CTD
PMID:34925699
NCBI chr 9:54,441,407...54,452,314
Ensembl chr 9:54,441,430...54,452,304
G
Siglec1
sialic acid binding Ig-like lectin 1, sialoadhesin
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SIGLEC1 mRNA
CTD
PMID:34925699
NCBI chr 2:130,911,140...130,928,697
Ensembl chr 2:130,911,140...130,928,685
G
Slamf8
SLAM family member 8
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SLAMF8 mRNA
CTD
PMID:34925699
NCBI chr 1:172,408,944...172,418,482
Ensembl chr 1:172,409,325...172,418,135
G
Slc10a6
solute carrier family 10 (sodium/bile acid cotransporter family), member 6
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SLC10A6 mRNA
CTD
PMID:34925699
NCBI chr 5:103,753,583...103,777,152
Ensembl chr 5:103,753,577...103,777,269
G
Slc17a8
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SLC17A8 mRNA
CTD
PMID:34925699
NCBI chr10:89,409,882...89,457,111
Ensembl chr10:89,409,882...89,457,115
G
Slc20a1
solute carrier family 20, member 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SLC20A1 mRNA
CTD
PMID:34925699
NCBI chr 2:129,038,662...129,053,535
Ensembl chr 2:129,040,684...129,053,536
G
Slc22a13
solute carrier family 22 (organic cation transporter), member 13
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SLC22A13 mRNA
CTD
PMID:34925699
NCBI chr 9:119,020,618...119,038,171
Ensembl chr 9:119,022,040...119,038,164
G
Slc22a20
solute carrier family 22 (organic anion transporter), member 20
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SLC22A20 mRNA
CTD
PMID:34925699
NCBI chr19:6,020,262...6,036,171
Ensembl chr19:6,020,262...6,036,171
G
Slc35f3
solute carrier family 35, member F3
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SLC35F3 mRNA
CTD
PMID:34925699
NCBI chr 8:126,865,155...127,122,726
Ensembl chr 8:126,865,734...127,122,717
G
Slc45a2
solute carrier family 45, member 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SLC45A2 mRNA
CTD
PMID:34925699
NCBI chr15:11,000,807...11,029,319
Ensembl chr15:11,000,807...11,029,319
G
Slc6a12
solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SLC6A12 mRNA
CTD
PMID:34925699
NCBI chr 6:121,319,533...121,342,732
Ensembl chr 6:121,320,035...121,342,734
G
Slc6a13
solute carrier family 6 (neurotransmitter transporter, GABA), member 13
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SLC6A13 mRNA
CTD
PMID:34925699
NCBI chr 6:121,277,247...121,314,680
Ensembl chr 6:121,277,186...121,314,692
G
Slc6a20b
solute carrier family 6 (neurotransmitter transporter), member 20B
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SLC6A20 mRNA
CTD
PMID:34925699
NCBI chr 9:123,422,888...123,461,603
Ensembl chr 9:123,419,865...123,461,630
G
Slc6a3
solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SLC6A3 mRNA
CTD
PMID:34925699
NCBI chr13:73,684,270...73,726,791
Ensembl chr13:73,684,866...73,726,791
G
Slc6a4
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SLC6A4 mRNA
CTD
PMID:34925699
NCBI chr11:76,889,423...76,923,169
Ensembl chr11:76,889,429...76,923,166
G
Slc6a7
solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SLC6A7 mRNA
CTD
PMID:34925699
NCBI chr18:61,128,448...61,147,484
Ensembl chr18:61,128,452...61,147,294
G
Slco1a5
solute carrier organic anion transporter family, member 1a5
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SLCO1A2 mRNA
CTD
PMID:34925699
NCBI chr 6:142,179,953...142,268,707
Ensembl chr 6:142,179,953...142,268,707
G
Slco2b1
solute carrier organic anion transporter family, member 2b1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SLCO2B1 mRNA
CTD
PMID:34925699
NCBI chr 7:99,307,011...99,360,547
Ensembl chr 7:99,307,011...99,360,547
G
Slit1
slit guidance ligand 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SLIT1 mRNA
CTD
PMID:34925699
NCBI chr19:41,586,263...41,735,714
Ensembl chr19:41,588,696...41,732,104
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Smim23
small integral membrane protein 23
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SMIM23 mRNA
CTD
PMID:34925699
NCBI chr11:32,770,376...32,774,594
Ensembl chr11:32,768,529...32,774,605
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Sod1
superoxide dismutase 1, soluble
multiple interactions
EXP
theaflavin-3,3'-digallate inhibits the reaction [Galactose results in decreased expression of SOD1 mRNA]
CTD
PMID:36638877
NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
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Sod2
superoxide dismutase 2, mitochondrial
increases expression
ISO
theaflavin-3,3'-digallate results in increased expression of SOD2 protein
CTD
PMID:35847580
NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
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Sostdc1
sclerostin domain containing 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SOSTDC1 mRNA
CTD
PMID:34925699
NCBI chr12:36,364,168...36,368,451
Ensembl chr12:36,364,138...36,368,451
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Sowaha
sosondowah ankyrin repeat domain family member A
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SOWAHA mRNA
CTD
PMID:34925699
NCBI chr11:53,367,405...53,371,022
Ensembl chr11:53,367,400...53,371,101
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Sowahb
sosondowah ankyrin repeat domain family member B
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SOWAHB mRNA
CTD
PMID:34925699
NCBI chr 5:93,188,981...93,192,910
Ensembl chr 5:93,188,982...93,192,881
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Sox15
SRY (sex determining region Y)-box 15
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SOX15 mRNA
CTD
PMID:34925699
NCBI chr11:69,545,863...69,547,553
Ensembl chr11:69,546,140...69,547,553
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Sox30
SRY (sex determining region Y)-box 30
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SOX30 mRNA
CTD
PMID:34925699
NCBI chr11:45,869,873...45,908,824
Ensembl chr11:45,871,137...45,908,821
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Sox9
SRY (sex determining region Y)-box 9
multiple interactions
ISO
theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of SOX9 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of SOX9 protein]
CTD
PMID:35847580
NCBI chr11:112,673,036...112,678,583
Ensembl chr11:112,673,050...112,678,586
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Sp1
trans-acting transcription factor 1
multiple interactions
ISO
theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased activity of SP1 protein]
CTD
PMID:12931129
NCBI chr15:102,314,751...102,344,839
Ensembl chr15:102,314,578...102,344,839
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Sp7
Sp7 transcription factor 7
multiple interactions
EXP
theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased expression of SP7 protein]
CTD
PMID:33833684
NCBI chr15:102,265,038...102,275,498
Ensembl chr15:102,265,041...102,275,617
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Spacdr
sperm acrosome developmental regulator
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SPACDR mRNA
CTD
PMID:34925699
NCBI chr 5:137,759,963...137,766,715
Ensembl chr 5:137,743,992...137,766,712
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Spdya
speedy/RINGO cell cycle regulator family, member A
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SPDYA mRNA
CTD
PMID:34925699
NCBI chr17:71,833,890...71,896,528
Ensembl chr17:71,859,056...71,896,528
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Spink2
serine peptidase inhibitor, Kazal type 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SPINK2 mRNA
CTD
PMID:34925699
NCBI chr 5:77,352,953...77,364,106
Ensembl chr 5:77,352,954...77,359,318
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Spry4
sprouty RTK signaling antagonist 4
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SPRY4 mRNA
CTD
PMID:34925699
NCBI chr18:38,719,300...38,734,400
Ensembl chr18:38,719,300...38,734,468
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Spx
spexin hormone
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SPX mRNA
CTD
PMID:34925699
NCBI chr 6:142,359,114...142,365,466
Ensembl chr 6:142,359,167...142,365,456
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Sqstm1
sequestosome 1
multiple interactions
ISO
[Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased expression of SQSTM1 protein
CTD
PMID:34350509
NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654
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Src
Rous sarcoma oncogene
multiple interactions
ISO
theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in increased phosphorylation of SRC protein]
CTD
PMID:35903325
NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782
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Sst
somatostatin
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SST mRNA
CTD
PMID:34925699
NCBI chr16:23,708,327...23,710,041
Ensembl chr16:23,708,323...23,709,708
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St8sia6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ST8SIA6 mRNA
CTD
PMID:34925699
NCBI chr 2:13,659,745...13,798,659
Ensembl chr 2:13,655,832...13,798,875
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Stab1
stabilin 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of STAB1 mRNA
CTD
PMID:34925699
NCBI chr14:30,860,974...30,890,616
Ensembl chr14:30,860,970...30,890,598
G
Stac2
SH3 and cysteine rich domain 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of STAC2 mRNA
CTD
PMID:34925699
NCBI chr11:97,927,449...97,944,288
Ensembl chr11:97,927,449...97,944,288
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Stk31
serine threonine kinase 31
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of STK31 mRNA
CTD
PMID:34925699
NCBI chr 6:49,372,441...49,446,440
Ensembl chr 6:49,372,538...49,446,435
G
Stk32b
serine/threonine kinase 32B
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of STK32B mRNA
CTD
PMID:34925699
NCBI chr 5:37,604,169...37,874,503
Ensembl chr 5:37,604,169...37,874,515
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Svopl
SV2 related protein homolog (rat)-like
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SVOPL mRNA
CTD
PMID:34925699
NCBI chr 6:37,960,674...38,023,944
Ensembl chr 6:37,960,674...38,023,931
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Sycp2
synaptonemal complex protein 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SYCP2 mRNA
CTD
PMID:34925699
NCBI chr 2:177,987,088...178,051,580
Ensembl chr 2:177,987,086...178,049,478
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Sycp3
synaptonemal complex protein 3
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SYCP3 mRNA
CTD
PMID:34925699
NCBI chr10:88,295,449...88,309,098
Ensembl chr10:88,295,431...88,309,098
G
Syndig1l
synapse differentiation inducing 1 like
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of SYNDIG1L mRNA
CTD
PMID:34925699
NCBI chr12:84,724,051...84,745,720
Ensembl chr12:84,724,051...84,745,605
G
Tac4
tachykinin 4
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of TAC4 mRNA
CTD
PMID:34925699
NCBI chr11:95,152,355...95,160,091
Ensembl chr11:95,152,355...95,160,091
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Tagln
transgelin
multiple interactions
ISO
theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in decreased expression of TAGLN protein]
CTD
PMID:35903325
NCBI chr 9:45,840,926...45,847,356
Ensembl chr 9:45,840,917...45,847,356
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Tcaf2
TRPM8 channel-associated factor 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of TCAF2 mRNA
CTD
PMID:34925699
NCBI chr 6:42,599,950...42,622,134
Ensembl chr 6:42,599,950...42,622,188
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Tead4
TEA domain family member 4
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of TEAD4 mRNA
CTD
PMID:34925699
NCBI chr 6:128,204,106...128,277,776
Ensembl chr 6:128,201,251...128,277,786
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Tecr
trans-2,3-enoyl-CoA reductase
multiple interactions
EXP
theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of TECR mRNA]
CTD
PMID:36105184
NCBI chr 8:84,298,327...84,321,120
Ensembl chr 8:84,298,327...84,334,600
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Tecta
tectorin alpha
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of TECTA mRNA
CTD
PMID:34925699
NCBI chr 9:42,240,918...42,312,986
Ensembl chr 9:42,240,915...42,311,225
G
Tef
thyrotroph embryonic factor
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of TEF mRNA
CTD
PMID:34925699
NCBI chr15:81,686,874...81,711,064
Ensembl chr15:81,686,622...81,711,064
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Tex29
testis expressed 29
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of TEX29 mRNA
CTD
PMID:34925699
NCBI chr 8:11,890,488...11,905,761
Ensembl chr 8:11,890,474...11,905,761
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Tll2
tolloid-like 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of TLL2 mRNA
CTD
PMID:34925699
NCBI chr19:41,069,379...41,199,287
Ensembl chr19:41,071,192...41,195,274
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Tlr9
toll-like receptor 9
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of TLR9 mRNA
CTD
PMID:34925699
NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082
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Tm7sf2
transmembrane 7 superfamily member 2
multiple interactions
EXP
theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of TM7SF2 mRNA]
CTD
PMID:36105184
NCBI chr19:6,112,851...6,117,880
Ensembl chr19:6,112,851...6,118,403
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Tmem119
transmembrane protein 119
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of TMEM119 mRNA
CTD
PMID:34925699
NCBI chr 5:113,931,790...113,938,457
Ensembl chr 5:113,931,790...113,938,577
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Tmem132e
transmembrane protein 132E
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of TMEM132E mRNA
CTD
PMID:34925699
NCBI chr11:82,279,281...82,338,447
Ensembl chr11:82,279,726...82,337,158
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Tmem150b
transmembrane protein 150B
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of TMEM150B mRNA
CTD
PMID:34925699
NCBI chr 7:4,709,831...4,728,250
Ensembl chr 7:4,709,831...4,728,248
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Tmem151a
transmembrane protein 151A
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of TMEM151A mRNA
CTD
PMID:34925699
NCBI chr19:5,120,859...5,135,519
Ensembl chr19:5,120,887...5,135,559
G
Tmem178b
transmembrane protein 178B
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of TMEM178B mRNA
CTD
PMID:34925699
NCBI chr 6:39,848,164...40,232,084
Ensembl chr 6:39,848,395...40,232,084
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Tmem40
transmembrane protein 40
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of TMEM40 mRNA
CTD
PMID:34925699
NCBI chr 6:115,706,092...115,739,427
Ensembl chr 6:115,706,092...115,739,371
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Tmprss7
transmembrane serine protease 7
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of TMPRSS7 mRNA
CTD
PMID:34925699
NCBI chr16:45,476,672...45,521,822
Ensembl chr16:45,476,678...45,514,021
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Tnf
tumor necrosis factor
multiple interactions decreases secretion affects expression
EXP ISO
theaflavin-3,3'-digallate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF mRNA]; theaflavin-3,3'-digallate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of TNF protein]; theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased expression of BGLAP protein]; theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased expression of CTNNB1 protein]; theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased expression of RUNX2 protein]; theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased expression of SP7 protein]; theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased phosphorylation of MAPK1 protein]; theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased phosphorylation of MAPK3 protein]; theaflavin-3,3'-digallate results in decreased expression of and results in decreased secretion of TNF protein theaflavin-3,3'-digallate results in decreased secretion of TNF protein theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of TNF mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased secretion of TNF protein] theaflavin-3,3'-digallate affects the expression of TNF mRNA
CTD
PMID:27871911 PMID:30874838 PMID:33833684 PMID:34925699 PMID:35847580 PMID:37651426 More...
NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
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Tnfrsf11a
tumor necrosis factor receptor superfamily, member 11a, NFKB activator
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of TNFRSF11A mRNA
CTD
PMID:34925699
NCBI chr 1:105,708,443...105,777,172
Ensembl chr 1:105,708,443...105,775,709
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Tnfsf11
tumor necrosis factor (ligand) superfamily, member 11
multiple interactions
EXP
[theaflavin-3,3'-digallate results in increased expression of NFE2L2 protein] inhibits the reaction [TNFSF11 protein results in increased abundance of Reactive Oxygen Species]; theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in decreased expression of CAT mRNA]; theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in decreased expression of GPX1 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in decreased expression of HMOX1 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in decreased expression of NFE2L2 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in increased expression of CD40 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA]; theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in increased expression of MMP9 mRNA]
CTD
PMID:32694992
NCBI chr14:78,514,886...78,545,483
Ensembl chr14:78,514,885...78,545,483
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Togaram2
TOG array regulator of axonemal microtubules 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of TOGARAM2 mRNA
CTD
PMID:34925699
NCBI chr17:71,980,153...72,036,666
Ensembl chr17:71,980,256...72,036,664
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Trarg1
trafficking regulator of GLUT4 (SLC2A4) 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of TUSC5 mRNA
CTD
PMID:34925699
NCBI chr11:76,570,699...76,589,490
Ensembl chr11:76,570,634...76,589,490
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Trem2
triggering receptor expressed on myeloid cells 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of TREM2 mRNA
CTD
PMID:34925699
NCBI chr17:48,653,429...48,659,304
Ensembl chr17:48,653,429...48,661,175
G
Trim31
tripartite motif-containing 31
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of TRIM31 mRNA
CTD
PMID:34925699
NCBI chr17:37,209,022...37,221,109
Ensembl chr17:37,209,010...37,221,106
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Trim36
tripartite motif-containing 36
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of TRIM36 mRNA
CTD
PMID:34925699
NCBI chr18:46,298,367...46,345,674
Ensembl chr18:46,298,367...46,345,674
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Trim72
tripartite motif-containing 72
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of TRIM72 mRNA
CTD
PMID:34925699
NCBI chr 7:127,602,684...127,610,565
Ensembl chr 7:127,603,121...127,610,205
G
Trpm6
transient receptor potential cation channel, subfamily M, member 6
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of TRPM6 mRNA
CTD
PMID:34925699
NCBI chr19:18,707,566...18,869,885
Ensembl chr19:18,727,347...18,869,875
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Trpv5
transient receptor potential cation channel, subfamily V, member 5
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of TRPV5 mRNA
CTD
PMID:34925699
NCBI chr 6:41,628,595...41,658,158
Ensembl chr 6:41,629,107...41,657,703
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Tspo2
translocator protein 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of TSPO2 mRNA
CTD
PMID:34925699
NCBI chr17:48,754,970...48,758,592
Ensembl chr17:48,754,935...48,758,550
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Ttc22
tetratricopeptide repeat domain 22
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of TTC22 mRNA
CTD
PMID:34925699
NCBI chr 4:106,479,646...106,497,393
Ensembl chr 4:106,479,629...106,497,386
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Uts2
urotensin 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of UTS2 mRNA
CTD
PMID:34925699
NCBI chr 4:151,081,554...151,086,267
Ensembl chr 4:151,081,554...151,086,267
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Vegfa
vascular endothelial growth factor A
decreases secretion multiple interactions
ISO
theaflavin-3,3'-digallate results in decreased secretion of VEGFA protein [Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased secretion of VEGFA protein
CTD
PMID:34350509
NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
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Vil1
villin 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of VIL1 mRNA
CTD
PMID:34925699
NCBI chr 1:74,448,543...74,474,719
Ensembl chr 1:74,448,535...74,474,718
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Vsig2
V-set and immunoglobulin domain containing 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of VSIG2 mRNA
CTD
PMID:34925699
NCBI chr 9:37,450,551...37,455,501
Ensembl chr 9:37,450,551...37,455,501
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Vsnl1
visinin-like 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of VSNL1 mRNA
CTD
PMID:34925699
NCBI chr12:11,375,258...11,486,579
Ensembl chr12:11,375,243...11,486,614
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Vsx2
visual system homeobox 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of VSX2 mRNA
CTD
PMID:34925699
NCBI chr12:84,616,602...84,642,231
Ensembl chr12:84,616,536...84,642,231
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Vwa3a
von Willebrand factor A domain containing 3A
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of VWA3A mRNA
CTD
PMID:34925699
NCBI chr 7:120,336,554...120,404,769
Ensembl chr 7:120,338,541...120,404,965
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Wdr38
WD repeat domain 38
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of WDR38 mRNA
CTD
PMID:34925699
NCBI chr 2:38,888,287...38,891,600
Ensembl chr 2:38,887,488...38,896,180
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Wdr86
WD repeat domain 86
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of WDR86 mRNA
CTD
PMID:34925699
NCBI chr 5:24,901,898...24,935,696
Ensembl chr 5:24,916,736...24,935,725
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Wnt16
wingless-type MMTV integration site family, member 16
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of WNT16 mRNA
CTD
PMID:34925699
NCBI chr 6:22,288,179...22,298,521
Ensembl chr 6:22,288,226...22,298,521
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Wnt6
wingless-type MMTV integration site family, member 6
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of WNT6 mRNA
CTD
PMID:34925699
NCBI chr 1:74,793,499...74,824,481
Ensembl chr 1:74,811,051...74,824,481
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Wnt7a
wingless-type MMTV integration site family, member 7A
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of WNT7A mRNA
CTD
PMID:34925699
NCBI chr 6:91,340,963...91,388,335
Ensembl chr 6:91,340,963...91,388,345
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Wt1
WT1 transcription factor
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of WT1 mRNA
CTD
PMID:34925699
NCBI chr 2:104,956,874...105,003,959
Ensembl chr 2:104,956,874...105,003,961
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Xbp1
X-box binding protein 1
multiple interactions
ISO
[Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased expression of and results in decreased splicing of XBP1 mRNA; theaflavin-3,3'-digallate results in decreased expression of and results in decreased splicing of XBP1 mRNA
CTD
PMID:34350509
NCBI chr11:5,470,641...5,475,993
Ensembl chr11:5,470,659...5,475,893
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Zar1
zygote arrest 1
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ZAR1 mRNA
CTD
PMID:34925699
NCBI chr 5:72,734,457...72,738,427
Ensembl chr 5:72,734,149...72,738,597
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Zar1l
zygote arrest 1-like
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ZAR1L mRNA
CTD
PMID:34925699
NCBI chr 5:150,430,520...150,441,659
Ensembl chr 5:150,430,520...150,441,629
G
Zfp385c
zinc finger protein 385C
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ZNF385C mRNA
CTD
PMID:34925699
NCBI chr11:100,517,045...100,583,292
Ensembl chr11:100,518,369...100,583,281
G
Zfyve28
zinc finger, FYVE domain containing 28
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ZFYVE28 mRNA
CTD
PMID:34925699
NCBI chr 5:34,352,237...34,445,796
Ensembl chr 5:34,352,237...34,445,793
G
Zp2
zona pellucida glycoprotein 2
affects expression
ISO
theaflavin-3,3'-digallate affects the expression of ZP2 mRNA
CTD
PMID:34925699
NCBI chr 7:119,725,985...119,744,514
Ensembl chr 7:119,725,995...119,744,514
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all