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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Theaflavin 3,3'-digallate
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Accession:CHEBI:136608 term browser browse the term
Synonyms:exact_synonym: (3,4,5-Trihydroxy-6-oxo-6H-benzo[7]annulene-1,8-diyl)bis[(2R,3R)-5,7-dihydroxy-3,4-dihydro-2H-chromene-2,3-diyl] bis(3,4,5-trihydroxybenzoate)
 related_synonym: Formula=C43H32O20;   InChI=1S/C43H32O20/c44-17-7-23(46)21-12-33(62-42(58)15-3-25(48)36(54)26(49)4-15)40(60-31(21)9-17)14-1-19-20(11-30(53)39(57)35(19)38(56)29(52)2-14)41-34(13-22-24(47)8-18(45)10-32(22)61-41)63-43(59)16-5-27(50)37(55)28(51)6-16/h1-11,33-34,40-41,44-51,53-55,57H,12-13H2,(H,52,56)/t33-,34-,40-,41-/m1/s1;   InChIKey=ZEASWHWETFMWCV-ISBUVJFSSA-N;   SMILES=O1[C@@H]([C@H](OC(=O)C2=CC(O)=C(O)C(O)=C2)CC=3C1=CC(O)=CC3O)C=4C5=CC([C@H]6OC=7C(C[C@H]6OC(=O)C8=CC(O)=C(O)C(O)=C8)=C(O)C=C(O)C7)=CC(=O)C(O)=C5C(O)=C(O)C4
 xref: Chemspider:410681
 xref_mesh: MESH:C585473



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Theaflavin 3,3'-digallate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 1700017N19Rik RIKEN cDNA 1700017N19 gene affects expression ISO theaflavin-3,3'-digallate affects the expression of C12ORF50 mRNA CTD PMID:34925699 NCBI chr10:100,426,346...100,454,257
Ensembl chr10:100,426,346...100,454,263
JBrowse link
G 4930590J08Rik RIKEN cDNA 4930590J08 gene affects expression ISO theaflavin-3,3'-digallate affects the expression of C3ORF20 mRNA CTD PMID:34925699 NCBI chr 6:91,877,732...91,928,717
Ensembl chr 6:91,879,790...91,927,706
JBrowse link
G AA986860 expressed sequence AA986860 affects expression ISO theaflavin-3,3'-digallate affects the expression of C1ORF116 mRNA CTD PMID:34925699 NCBI chr 1:130,659,707...130,672,359
Ensembl chr 1:130,659,713...130,672,359
JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of ABCC2 mRNA CTD PMID:34925699 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
JBrowse link
G Acadm acyl-Coenzyme A dehydrogenase, medium chain multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of ACADM mRNA] CTD PMID:36105184 NCBI chr 3:153,627,990...153,650,280
Ensembl chr 3:153,627,994...153,650,269
JBrowse link
G Acan aggrecan multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of ACAN mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of ACAN protein] CTD PMID:35847580 NCBI chr 7:78,702,974...78,764,847
Ensembl chr 7:78,703,231...78,764,847
JBrowse link
G Accsl 1-aminocyclopropane-1-carboxylate synthase (inactive)-like affects expression ISO theaflavin-3,3'-digallate affects the expression of ACCSL mRNA CTD PMID:34925699 NCBI chr 2:93,685,705...93,760,827
Ensembl chr 2:93,685,706...93,760,827
JBrowse link
G Ace2 angiotensin converting enzyme 2 affects binding ISO theaflavin-3,3'-digallate binds to ACE2 protein CTD PMID:34138966 NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416
JBrowse link
G Ache acetylcholinesterase multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [Galactose results in increased activity of ACHE protein] CTD PMID:36638877 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
JBrowse link
G Acot6 acyl-CoA thioesterase 6 affects expression ISO theaflavin-3,3'-digallate affects the expression of ACOT6 mRNA CTD PMID:34925699 NCBI chr12:84,147,538...84,158,128
Ensembl chr12:84,147,428...84,158,123
JBrowse link
G Acrbp proacrosin binding protein affects expression ISO theaflavin-3,3'-digallate affects the expression of ACRBP mRNA CTD PMID:34925699 NCBI chr 6:125,026,890...125,040,228
Ensembl chr 6:125,026,652...125,040,230
JBrowse link
G Acta2 actin alpha 2, smooth muscle, aorta multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in decreased expression of ACTA2 protein] CTD PMID:35903325 NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990
JBrowse link
G Actl6b actin-like 6B affects expression ISO theaflavin-3,3'-digallate affects the expression of ACTL6B mRNA CTD PMID:34925699 NCBI chr 5:137,551,784...137,567,844
Ensembl chr 5:137,551,779...137,567,844
JBrowse link
G Adam30 a disintegrin and metallopeptidase domain 30 affects expression ISO theaflavin-3,3'-digallate affects the expression of ADAM30 mRNA CTD PMID:34925699 NCBI chr 3:98,067,950...98,071,485
Ensembl chr 3:98,067,946...98,071,485
JBrowse link
G Adam32 a disintegrin and metallopeptidase domain 32 affects expression ISO theaflavin-3,3'-digallate affects the expression of ADAM32 mRNA CTD PMID:34925699 NCBI chr 8:25,326,159...25,438,933
Ensembl chr 8:25,326,156...25,438,820
JBrowse link
G Adam33 a disintegrin and metallopeptidase domain 33 affects expression ISO theaflavin-3,3'-digallate affects the expression of ADAM33 mRNA CTD PMID:34925699 NCBI chr 2:130,892,739...130,905,734
Ensembl chr 2:130,892,511...130,905,734
JBrowse link
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif 5 multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of ADAMTS5 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of ADAMTS5 protein] CTD PMID:35847580 NCBI chr16:85,655,045...85,698,013
Ensembl chr16:85,653,061...85,698,716
JBrowse link
G Add2 adducin 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of ADD2 mRNA CTD PMID:34925699 NCBI chr 6:86,005,663...86,101,391
Ensembl chr 6:86,005,663...86,101,391
JBrowse link
G Adgrf2 adhesion G protein-coupled receptor F2 affects expression ISO theaflavin-3,3'-digallate affects the expression of ADGRF2P mRNA CTD PMID:34925699 NCBI chr17:43,004,919...43,054,646
Ensembl chr17:43,007,021...43,053,070
JBrowse link
G Adgrg7 adhesion G protein-coupled receptor G7 affects expression ISO theaflavin-3,3'-digallate affects the expression of ADGRG7 mRNA CTD PMID:34925699 NCBI chr16:56,544,972...56,616,369
Ensembl chr16:56,544,972...56,616,218
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [Methylmercury Compounds results in increased secretion of ADIPOQ protein] CTD PMID:31195622 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778
JBrowse link
G Adra2b adrenergic receptor, alpha 2b affects expression ISO theaflavin-3,3'-digallate affects the expression of ADRA2B mRNA CTD PMID:34925699 NCBI chr 2:127,205,099...127,209,141
Ensembl chr 2:127,205,128...127,209,141
JBrowse link
G Adtrp androgen dependent TFPI regulating protein affects expression ISO theaflavin-3,3'-digallate affects the expression of ADTRP mRNA CTD PMID:34925699 NCBI chr13:41,916,621...42,001,092
Ensembl chr13:41,916,624...42,001,160
JBrowse link
G Agt angiotensinogen multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in decreased abundance of Nitric Oxide]; theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in decreased activity of CAT protein]; theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in decreased phosphorylation of NFATC3 protein]; theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]; theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in increased expression of ANP mRNA]; theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in increased expression of BNP mRNA]; theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in increased expression of PPP3CA protein] CTD PMID:35406003 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445
JBrowse link
G Ahr aryl-hydrocarbon receptor multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [Tetrachlorodibenzodioxin binds to and affects the activity of AHR protein] CTD PMID:15914905 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
JBrowse link
G Aipl1 aryl hydrocarbon receptor-interacting protein-like 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of AIPL1 mRNA CTD PMID:34925699 NCBI chr11:71,919,527...71,933,184
Ensembl chr11:71,918,789...71,928,335
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of AKT1 protein]; theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in increased phosphorylation of AKT1 protein]
theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein]
CTD PMID:12931129 PMID:35847580 PMID:35903325 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Allc allantoicase affects expression ISO theaflavin-3,3'-digallate affects the expression of ALLC mRNA CTD PMID:34925699 NCBI chr12:28,603,754...28,632,527
Ensembl chr12:28,603,754...28,632,522
JBrowse link
G Alppl2 alkaline phosphatase, placental-like 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of ALPPL2 mRNA CTD PMID:34925699 NCBI chr 1:87,014,412...87,023,656
Ensembl chr 1:87,014,416...87,017,650
JBrowse link
G Amh anti-Mullerian hormone increases expression EXP theaflavin-3,3'-digallate results in increased expression of AMH mRNA CTD PMID:34925699 NCBI chr10:80,641,074...80,643,513
Ensembl chr10:80,641,077...80,643,482
JBrowse link
G Ampd1 adenosine monophosphate deaminase 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of AMPD1 mRNA CTD PMID:34925699 NCBI chr 3:102,981,330...103,007,038
Ensembl chr 3:102,981,330...103,007,036
JBrowse link
G Amz1 archaelysin family metallopeptidase 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of AMZ1 mRNA CTD PMID:34925699 NCBI chr 5:140,709,882...140,739,067
Ensembl chr 5:140,709,882...140,747,194
JBrowse link
G Ang angiogenin, ribonuclease, RNase A family, 5 multiple interactions
decreases secretion
ISO [Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased secretion of ANG protein
theaflavin-3,3'-digallate results in decreased secretion of ANG protein
CTD PMID:34350509 NCBI chr14:51,328,607...51,339,462
Ensembl chr14:51,328,607...51,339,466
JBrowse link
G Ankub1 ankyrin repeat and ubiquitin domain containing 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of ANKUB1 mRNA CTD PMID:34925699 NCBI chr 3:57,574,843...57,599,958
Ensembl chr 3:57,564,814...57,600,220
JBrowse link
G Apoa4 apolipoprotein A-IV affects expression ISO theaflavin-3,3'-digallate affects the expression of APOA4 mRNA CTD PMID:34925699 NCBI chr 9:46,152,142...46,154,756
Ensembl chr 9:46,151,994...46,154,757
JBrowse link
G Apol9a apolipoprotein L 9a affects expression ISO theaflavin-3,3'-digallate affects the expression of APOL4 mRNA CTD PMID:34925699 NCBI chr15:77,287,989...77,295,280
Ensembl chr15:77,287,989...77,295,335
JBrowse link
G Arc activity regulated cytoskeletal-associated protein affects expression ISO theaflavin-3,3'-digallate affects the expression of ARC mRNA CTD PMID:34925699 NCBI chr15:74,540,930...74,544,419
Ensembl chr15:74,540,932...74,544,419
JBrowse link
G Areg amphiregulin affects expression ISO theaflavin-3,3'-digallate affects the expression of AREG mRNA CTD PMID:34925699 NCBI chr 5:91,287,458...91,296,291
Ensembl chr 5:91,287,458...91,296,291
JBrowse link
G Asb15 ankyrin repeat and SOCS box-containing 15 affects expression ISO theaflavin-3,3'-digallate affects the expression of ASB15 mRNA CTD PMID:34925699 NCBI chr 6:24,528,143...24,573,163
Ensembl chr 6:24,528,143...24,573,163
JBrowse link
G Asic4 acid-sensing ion channel family member 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of ASIC4 mRNA CTD PMID:34925699 NCBI chr 1:75,426,467...75,450,984
Ensembl chr 1:75,427,080...75,450,987
JBrowse link
G Atoh1 atonal bHLH transcription factor 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of ATOH1 mRNA CTD PMID:34925699 NCBI chr 6:64,706,109...64,708,229
Ensembl chr 6:64,706,109...64,708,229
JBrowse link
G Atp10b ATPase, class V, type 10B affects expression ISO theaflavin-3,3'-digallate affects the expression of ATP10B mRNA CTD PMID:34925699 NCBI chr11:42,902,991...43,153,112
Ensembl chr11:43,040,704...43,153,112
JBrowse link
G Atp1a4 ATPase, Na+/K+ transporting, alpha 4 polypeptide affects expression ISO theaflavin-3,3'-digallate affects the expression of ATP1A4 mRNA CTD PMID:34925699 NCBI chr 1:172,051,075...172,085,991
Ensembl chr 1:172,051,080...172,085,981
JBrowse link
G Atp1b4 ATPase Na+/K+ transporting, beta 4 polypeptide affects expression ISO theaflavin-3,3'-digallate affects the expression of ATP1B4 mRNA CTD PMID:34925699 NCBI chr  X:37,404,999...37,425,661
Ensembl chr  X:37,405,061...37,425,646
JBrowse link
G Atp2a1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of ATP2A1 mRNA CTD PMID:34925699 NCBI chr 7:126,045,032...126,062,245
Ensembl chr 7:126,045,030...126,062,280
JBrowse link
G Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of ATP2B2 mRNA CTD PMID:34925699 NCBI chr 6:113,720,803...114,019,574
Ensembl chr 6:113,720,792...114,019,574
JBrowse link
G Avil advillin affects expression ISO theaflavin-3,3'-digallate affects the expression of AVIL mRNA CTD PMID:34925699 NCBI chr10:126,835,933...126,856,857
Ensembl chr10:126,836,578...126,856,863
JBrowse link
G Baat bile acid-Coenzyme A: amino acid N-acyltransferase affects expression ISO theaflavin-3,3'-digallate affects the expression of BAAT mRNA CTD PMID:34925699 NCBI chr 4:49,489,416...49,507,915
Ensembl chr 4:49,489,422...49,506,557
JBrowse link
G Bax BCL2-associated X protein decreases expression
multiple interactions
increases expression
ISO theaflavin-3,3'-digallate results in decreased expression of BAX protein
[Methotrexate co-treated with theaflavin-3,3'-digallate] results in increased expression of BAX protein
theaflavin-3,3'-digallate results in increased expression of BAX protein
theaflavin-3,3'-digallate results in decreased expression of BAX mRNA; theaflavin-3,3'-digallate results in decreased expression of BAX protein
CTD PMID:30769778 PMID:32964953 PMID:34350509 PMID:34925699 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G BC034090 cDNA sequence BC034090 affects expression ISO theaflavin-3,3'-digallate affects the expression of KIAA1614 mRNA CTD PMID:34925699 NCBI chr 1:155,088,217...155,123,504
Ensembl chr 1:155,088,217...155,120,190
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression
increases expression
multiple interactions
ISO theaflavin-3,3'-digallate results in decreased expression of BCL2 protein
theaflavin-3,3'-digallate results in increased expression of BCL2 mRNA; theaflavin-3,3'-digallate results in increased expression of BCL2 protein
[Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased expression of BCL2 protein
CTD PMID:32964953 PMID:34350509 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bcl2l1 BCL2-like 1 decreases expression ISO theaflavin-3,3'-digallate results in decreased expression of BCL2L1 protein CTD PMID:30769778 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648
JBrowse link
G Becn1 beclin 1, autophagy related multiple interactions
decreases expression
ISO [Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased expression of BECN1 protein
theaflavin-3,3'-digallate results in decreased expression of BECN1 protein
CTD PMID:34350509 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112
JBrowse link
G Bglap bone gamma carboxyglutamate protein multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased expression of BGLAP protein]; theaflavin-3,3'-digallate results in increased expression of and results in increased secretion of BGLAP protein CTD PMID:33833684 NCBI chr 3:88,290,802...88,291,773
Ensembl chr 3:88,290,808...88,291,771
JBrowse link
G Bmp15 bone morphogenetic protein 15 increases expression EXP theaflavin-3,3'-digallate results in increased expression of BMP15 mRNA CTD PMID:34925699 NCBI chr  X:6,226,108...6,232,778
Ensembl chr  X:6,226,161...6,232,775
JBrowse link
G Bnc1 basonuclin zinc finger protein 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of BNC1 mRNA CTD PMID:34925699 NCBI chr 7:81,616,401...81,642,047
Ensembl chr 7:81,616,401...81,642,055
JBrowse link
G Bnipl BCL2/adenovirus E1B 19kD interacting protein like affects expression ISO theaflavin-3,3'-digallate affects the expression of BNIPL mRNA CTD PMID:34925699 NCBI chr 3:95,148,587...95,158,504
Ensembl chr 3:95,148,582...95,158,504
JBrowse link
G Bop1 block of proliferation 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of BOP1 mRNA CTD PMID:34925699 NCBI chr15:76,337,188...76,361,449
Ensembl chr15:76,337,189...76,361,477
JBrowse link
G Btla B and T lymphocyte associated affects expression ISO theaflavin-3,3'-digallate affects the expression of BTLA mRNA CTD PMID:34925699 NCBI chr16:45,043,121...45,073,258
Ensembl chr16:45,044,678...45,078,033
JBrowse link
G Btn1a1 butyrophilin, subfamily 1, member A1 affects expression ISO theaflavin-3,3'-digallate affects the expression of BTN1A1 mRNA CTD PMID:34925699 NCBI chr13:23,641,154...23,650,084
Ensembl chr13:23,641,162...23,650,071
JBrowse link
G Bysl bystin-like affects expression ISO theaflavin-3,3'-digallate affects the expression of BYSL mRNA CTD PMID:34925699 NCBI chr17:47,910,256...47,922,417
Ensembl chr17:47,910,256...47,922,417
JBrowse link
G C1qtnf2 C1q and tumor necrosis factor related protein 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of C1QTNF2 mRNA CTD PMID:34925699 NCBI chr11:43,364,984...43,382,485
Ensembl chr11:43,365,103...43,382,352
JBrowse link
G C5ar2 complement component 5a receptor 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of C5AR2 mRNA CTD PMID:34925699 NCBI chr 7:15,968,512...15,978,079
Ensembl chr 7:15,968,510...15,978,079
JBrowse link
G C9 complement component 9 affects expression ISO theaflavin-3,3'-digallate affects the expression of C9 mRNA CTD PMID:34925699 NCBI chr15:6,474,827...6,528,306
Ensembl chr15:6,474,808...6,528,232
JBrowse link
G Capn11 calpain 11 affects expression ISO theaflavin-3,3'-digallate affects the expression of CAPN11 mRNA CTD PMID:34925699 NCBI chr17:45,941,117...45,970,400
Ensembl chr17:45,941,130...45,970,251
JBrowse link
G Casp3 caspase 3 increases activity
decreases expression
multiple interactions
ISO theaflavin-3,3'-digallate results in increased activity of CASP3 protein
theaflavin-3,3'-digallate results in decreased expression of CASP3 protein
theaflavin-3,3'-digallate results in decreased expression of CASP3 mRNA; theaflavin-3,3'-digallate results in decreased expression of CASP3 protein
[Methotrexate co-treated with theaflavin-3,3'-digallate] results in increased expression of and results in increased cleavage of and results in increased activity of CASP3 protein; theaflavin-3,3'-digallate results in increased expression of and results in increased cleavage of and results in increased activity of CASP3 protein
CTD PMID:30769778 PMID:32964953 PMID:34350509 PMID:34925699 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp8 caspase 8 increases activity ISO theaflavin-3,3'-digallate results in increased activity of CASP8 protein CTD PMID:30769778 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
ISO [Methotrexate co-treated with theaflavin-3,3'-digallate] results in increased expression of and results in increased cleavage of and results in increased activity of CASP9 protein; theaflavin-3,3'-digallate results in increased expression of and results in increased cleavage of and results in increased activity of CASP9 protein
theaflavin-3,3'-digallate results in increased activity of CASP9 protein
CTD PMID:30769778 PMID:34350509 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Cass4 Cas scaffolding protein family member 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of CASS4 mRNA CTD PMID:34925699 NCBI chr 2:172,234,998...172,275,672
Ensembl chr 2:172,235,714...172,275,677
JBrowse link
G Cat catalase multiple interactions ISO
EXP
theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in decreased activity of CAT protein]
theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in decreased expression of CAT mRNA]
CTD PMID:32694992 PMID:35406003 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Cc2d2b coiled-coil and C2 domain containing 2B affects expression ISO theaflavin-3,3'-digallate affects the expression of CC2D2B mRNA CTD PMID:34925699 NCBI chr19:40,737,197...40,818,227
Ensembl chr19:40,737,197...40,816,187
JBrowse link
G Ccdc17 coiled-coil domain containing 17 affects expression ISO theaflavin-3,3'-digallate affects the expression of CCDC17 mRNA CTD PMID:34925699 NCBI chr 4:116,453,927...116,457,463
Ensembl chr 4:116,453,851...116,457,463
JBrowse link
G Ccdc62 coiled-coil domain containing 62 affects expression ISO theaflavin-3,3'-digallate affects the expression of CCDC62 mRNA CTD PMID:34925699 NCBI chr 5:124,068,683...124,107,958
Ensembl chr 5:124,065,481...124,107,958
JBrowse link
G Ccdc65 coiled-coil domain containing 65 affects expression ISO theaflavin-3,3'-digallate affects the expression of CCDC65 mRNA CTD PMID:34925699 NCBI chr15:98,606,075...98,621,221
Ensembl chr15:98,606,088...98,621,217
JBrowse link
G Ccdc70 coiled-coil domain containing 70 affects expression ISO theaflavin-3,3'-digallate affects the expression of CCDC70 mRNA CTD PMID:34925699 NCBI chr 8:22,459,791...22,464,071
Ensembl chr 8:22,459,791...22,464,057
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of CCL4 mRNA CTD PMID:34925699 NCBI chr11:83,553,410...83,555,509
Ensembl chr11:83,553,410...83,555,509
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression
ISO CDKN1B promotes the reaction [theaflavin-3,3'-digallate results in decreased expression of CCND1 protein] CTD PMID:30769778 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of CCR1 mRNA CTD PMID:34925699 NCBI chr 9:123,762,163...123,768,729
Ensembl chr 9:123,762,161...123,768,729
JBrowse link
G Ccr6 C-C motif chemokine receptor 6 affects expression ISO theaflavin-3,3'-digallate affects the expression of CCR6 mRNA CTD PMID:34925699 NCBI chr17:8,454,875...8,477,353
Ensembl chr17:8,454,875...8,475,973
JBrowse link
G Cd300e CD300E molecule affects expression ISO theaflavin-3,3'-digallate affects the expression of CD300E mRNA CTD PMID:34925699 NCBI chr11:114,942,743...114,957,502
Ensembl chr11:114,942,743...114,957,500
JBrowse link
G Cd33 CD33 molecule affects expression ISO theaflavin-3,3'-digallate affects the expression of CD33 mRNA CTD PMID:34925699 NCBI chr 7:43,176,823...43,186,679
Ensembl chr 7:43,173,640...43,193,852
JBrowse link
G Cd3g CD3 antigen, gamma polypeptide affects expression ISO theaflavin-3,3'-digallate affects the expression of CD3G mRNA CTD PMID:34925699 NCBI chr 9:44,880,870...44,891,729
Ensembl chr 9:44,880,870...44,891,729
JBrowse link
G Cd40 CD40 antigen multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in increased expression of CD40 mRNA] CTD PMID:32694992 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868
JBrowse link
G Cd69 CD69 antigen affects expression ISO theaflavin-3,3'-digallate affects the expression of CD69 mRNA CTD PMID:34925699 NCBI chr 6:129,244,287...129,252,332
Ensembl chr 6:129,244,288...129,252,399
JBrowse link
G Cdc42ep1 CDC42 effector protein 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of CDC42EP1 mRNA CTD PMID:34925699 NCBI chr15:78,726,847...78,735,102
Ensembl chr15:78,726,824...78,735,097
JBrowse link
G Cdk4 cyclin dependent kinase 4 decreases expression
multiple interactions
ISO theaflavin-3,3'-digallate results in decreased expression of CDK4 protein
CDKN1B promotes the reaction [theaflavin-3,3'-digallate results in decreased expression of CDK4 protein]
CTD PMID:30769778 NCBI chr10:126,899,404...126,903,157
Ensembl chr10:126,899,403...126,903,789
JBrowse link
G Cdk5r1 cyclin dependent kinase 5, regulatory subunit 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of CDK5R1 mRNA CTD PMID:34925699 NCBI chr11:80,367,849...80,372,010
Ensembl chr11:80,367,849...80,372,010
JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B increases expression
multiple interactions
ISO theaflavin-3,3'-digallate results in increased expression of CDKN1B protein
CDKN1B promotes the reaction [theaflavin-3,3'-digallate results in decreased expression of and results in decreased phosphorylation of RB1 protein]; CDKN1B promotes the reaction [theaflavin-3,3'-digallate results in decreased expression of CCND1 protein]; CDKN1B promotes the reaction [theaflavin-3,3'-digallate results in decreased expression of CDK4 protein]
CTD PMID:30769778 NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476
JBrowse link
G Cdx2 caudal type homeobox 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of CDX2 mRNA CTD PMID:34925699 NCBI chr 5:147,237,710...147,244,059
Ensembl chr 5:147,237,615...147,244,080
JBrowse link
G Ceacam10 CEA cell adhesion molecule 10 affects expression ISO theaflavin-3,3'-digallate affects the expression of CEACAM4 mRNA CTD PMID:34925699 NCBI chr 7:24,476,592...24,484,081
Ensembl chr 7:24,476,631...24,484,082
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha affects expression ISO theaflavin-3,3'-digallate affects the expression of CEBPA mRNA CTD PMID:34925699 NCBI chr 7:34,818,718...34,821,353
Ensembl chr 7:34,818,718...34,821,353
JBrowse link
G Cfap141 cilia and flagella associated protein 141 affects expression ISO theaflavin-3,3'-digallate affects the expression of CFAP141 mRNA CTD PMID:34925699 NCBI chr 3:89,970,115...89,975,654
Ensembl chr 3:89,970,103...89,973,182
JBrowse link
G Cfap161 cilia and flagella associated protein 161 affects expression ISO theaflavin-3,3'-digallate affects the expression of CFAP161 mRNA CTD PMID:34925699 NCBI chr 7:83,424,820...83,447,528
Ensembl chr 7:83,423,309...83,444,088
JBrowse link
G Cfap206 cilia and flagella associated protein 206 affects expression ISO theaflavin-3,3'-digallate affects the expression of CFAP206 mRNA CTD PMID:34925699 NCBI chr 4:34,688,574...34,730,263
Ensembl chr 4:34,688,559...34,730,206
JBrowse link
G Cfap276 cilia and flagella associated protein 276 affects expression ISO theaflavin-3,3'-digallate affects the expression of CFAP276 mRNA CTD PMID:34925699 NCBI chr 3:108,444,900...108,452,013
Ensembl chr 3:108,441,466...108,452,039
JBrowse link
G Chac1 ChaC, cation transport regulator 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of CHAC1 mRNA CTD PMID:34925699 NCBI chr 2:119,181,723...119,184,807
Ensembl chr 2:119,181,710...119,184,862
JBrowse link
G Chd5 chromodomain helicase DNA binding protein 5 affects expression ISO theaflavin-3,3'-digallate affects the expression of CHD5 mRNA CTD PMID:34925699 NCBI chr 4:152,423,103...152,474,651
Ensembl chr 4:152,423,108...152,474,651
JBrowse link
G Chek2 checkpoint kinase 2 increases phosphorylation ISO theaflavin-3,3'-digallate results in increased phosphorylation of CHEK2 protein CTD PMID:30769778 NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011
JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 affects expression ISO theaflavin-3,3'-digallate affects the expression of CHRM5 mRNA CTD PMID:34925699 NCBI chr 2:112,306,055...112,365,487
Ensembl chr 2:112,309,516...112,311,114
JBrowse link
G Chrna3 cholinergic receptor, nicotinic, alpha polypeptide 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of CHRNA3 mRNA CTD PMID:34925699 NCBI chr 9:54,917,401...54,933,846
Ensembl chr 9:54,917,395...54,933,846
JBrowse link
G Chrna4 cholinergic receptor, nicotinic, alpha polypeptide 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of CHRNA4 mRNA CTD PMID:34925699 NCBI chr 2:180,664,104...180,685,339
Ensembl chr 2:180,660,173...180,685,339
JBrowse link
G Clcn1 chloride channel, voltage-sensitive 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of CLCN1 mRNA CTD PMID:34925699 NCBI chr 6:42,263,552...42,292,693
Ensembl chr 6:42,263,619...42,292,690
JBrowse link
G Cldn19 claudin 19 affects expression ISO theaflavin-3,3'-digallate affects the expression of CLDN19 mRNA CTD PMID:34925699 NCBI chr 4:119,112,638...119,119,635
Ensembl chr 4:119,112,611...119,119,635
JBrowse link
G Clec4a1 C-type lectin domain family 4, member a1 affects expression ISO theaflavin-3,3'-digallate affects the expression of ZNF705A mRNA CTD PMID:34925699 NCBI chr 6:122,898,807...122,911,578
Ensembl chr 6:122,898,807...122,911,578
JBrowse link
G Clec5a C-type lectin domain family 5, member a affects expression ISO theaflavin-3,3'-digallate affects the expression of CLEC5A mRNA CTD PMID:34925699 NCBI chr 6:40,551,832...40,562,739
Ensembl chr 6:40,551,828...40,562,755
JBrowse link
G Clec7a C-type lectin domain family 7, member a affects expression ISO theaflavin-3,3'-digallate affects the expression of CLEC7A mRNA CTD PMID:34925699 NCBI chr 6:129,438,554...129,449,748
Ensembl chr 6:129,438,554...129,449,742
JBrowse link
G Cmtm2b CKLF-like MARVEL transmembrane domain containing 2B affects expression ISO theaflavin-3,3'-digallate affects the expression of CMTM2 mRNA CTD PMID:34925699 NCBI chr 8:105,048,838...105,057,396
Ensembl chr 8:105,048,862...105,057,396
JBrowse link
G Cnbd2 cyclic nucleotide binding domain containing 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of CNBD2 mRNA CTD PMID:34925699 NCBI chr 2:156,153,866...156,217,558
Ensembl chr 2:156,154,219...156,217,558
JBrowse link
G Cndp1 carnosine dipeptidase 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of CNDP1 mRNA CTD PMID:34925699 NCBI chr18:84,628,509...84,668,359
Ensembl chr18:84,628,634...84,668,220
JBrowse link
G Cnr1 cannabinoid receptor 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of CNR1 mRNA CTD PMID:34925699 NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831
JBrowse link
G Col11a2 collagen, type XI, alpha 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of COL11A2 mRNA CTD PMID:34925699 NCBI chr17:34,257,462...34,285,659
Ensembl chr17:34,258,411...34,285,659
JBrowse link
G Col2a1 collagen, type II, alpha 1 multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of COL2A1 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of COL2A1 protein] CTD PMID:35847580 NCBI chr15:97,873,483...97,902,525
Ensembl chr15:97,873,483...97,902,576
JBrowse link
G Cplx3 complexin 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of CPLX3 mRNA CTD PMID:34925699 NCBI chr 9:57,507,275...57,513,564
Ensembl chr 9:57,507,275...57,513,564
JBrowse link
G Cr2 complement receptor 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of CR2 mRNA CTD PMID:34925699 NCBI chr 1:194,819,120...194,859,096
Ensembl chr 1:194,819,119...194,859,024
JBrowse link
G Crybb2 crystallin, beta B2 affects expression ISO theaflavin-3,3'-digallate affects the expression of CRYBB2 mRNA CTD PMID:34925699 NCBI chr 5:113,206,124...113,217,983
Ensembl chr 5:113,206,124...113,217,983
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased expression of CTNNB1 protein] CTD PMID:33833684 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
JBrowse link
G Ctsk cathepsin K multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA] CTD PMID:32694992 NCBI chr 3:95,406,521...95,416,698
Ensembl chr 3:95,406,567...95,416,673
JBrowse link
G Ctsl cathepsin L decreases expression ISO theaflavin-3,3'-digallate results in decreased expression of CTSL protein CTD PMID:34138966 NCBI chr13:64,509,704...64,518,586
Ensembl chr13:64,507,151...64,518,704
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of CYP1A2 mRNA] CTD PMID:36105184 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of CYP26A1 mRNA CTD PMID:34925699 NCBI chr19:37,686,186...37,689,984
Ensembl chr19:37,686,246...37,689,984
JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 affects expression ISO theaflavin-3,3'-digallate affects the expression of CYP2B6 mRNA CTD PMID:34925699 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049
JBrowse link
G Cyp2c70 cytochrome P450, family 2, subfamily c, polypeptide 70 multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of CYP2C70 mRNA] CTD PMID:36105184 NCBI chr19:40,141,805...40,175,730
Ensembl chr19:40,141,797...40,175,777
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of CYP4B1 mRNA CTD PMID:34925699 NCBI chr 4:115,481,895...115,504,918
Ensembl chr 4:115,481,922...115,504,920
JBrowse link
G Cyp4f14 cytochrome P450, family 4, subfamily f, polypeptide 14 multiple interactions
affects expression
EXP
ISO
theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of CYP4F14 mRNA]
theaflavin-3,3'-digallate affects the expression of CYP4F12 mRNA
CTD PMID:34925699 PMID:36105184 NCBI chr17:33,122,331...33,136,353
Ensembl chr17:33,124,044...33,136,316
JBrowse link
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of CYP7A1 mRNA CTD PMID:34925699 NCBI chr 4:6,265,612...6,275,632
Ensembl chr 4:6,265,612...6,275,633
JBrowse link
G D630039A03Rik RIKEN cDNA D630039A03 gene affects expression ISO theaflavin-3,3'-digallate affects the expression of C9ORF152 mRNA CTD PMID:34925699 NCBI chr 4:57,908,384...57,916,264
Ensembl chr 4:57,908,483...57,916,297
JBrowse link
G Dcaf12l1 DDB1 and CUL4 associated factor 12-like 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of DCAF12L1 mRNA CTD PMID:34925699 NCBI chr  X:43,875,444...43,879,074
Ensembl chr  X:43,875,447...43,879,074
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
affects expression
ISO [Methotrexate co-treated with theaflavin-3,3'-digallate] results in increased expression of DDIT3 protein
theaflavin-3,3'-digallate affects the expression of DDIT3 mRNA
CTD PMID:34350509 PMID:34925699 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157
JBrowse link
G Dgkb diacylglycerol kinase, beta affects expression ISO theaflavin-3,3'-digallate affects the expression of DGKB mRNA CTD PMID:34925699 NCBI chr12:37,930,169...38,684,238
Ensembl chr12:37,867,725...38,684,238
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of DHCR7 mRNA] CTD PMID:36105184 NCBI chr 7:143,376,827...143,402,147
Ensembl chr 7:143,376,882...143,402,147
JBrowse link
G Dhrs9 dehydrogenase/reductase 9 affects expression ISO theaflavin-3,3'-digallate affects the expression of DHRS9 mRNA CTD PMID:34925699 NCBI chr 2:69,210,806...69,233,430
Ensembl chr 2:69,210,789...69,234,877
JBrowse link
G Dkk4 dickkopf WNT signaling pathway inhibitor 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of DKK4 mRNA CTD PMID:34925699 NCBI chr 8:23,113,701...23,117,563
Ensembl chr 8:23,114,059...23,117,563
JBrowse link
G Dlx1 distal-less homeobox 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of DLX1 mRNA CTD PMID:34925699 NCBI chr 2:71,358,457...71,364,325
Ensembl chr 2:71,358,457...71,364,325
JBrowse link
G Dnaaf1 dynein, axonemal assembly factor 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of DNAAF1 mRNA CTD PMID:34925699 NCBI chr 8:120,301,974...120,325,193
Ensembl chr 8:120,301,974...120,325,193
JBrowse link
G Dnah11 dynein, axonemal, heavy chain 11 affects expression ISO theaflavin-3,3'-digallate affects the expression of DNAH11 mRNA CTD PMID:34925699 NCBI chr12:117,841,717...118,162,778
Ensembl chr12:117,841,717...118,162,778
JBrowse link
G Dnah12 dynein, axonemal, heavy chain 12 affects expression ISO theaflavin-3,3'-digallate affects the expression of DNAH12 mRNA CTD PMID:34925699 NCBI chr14:26,412,709...26,614,250
Ensembl chr14:26,414,429...26,613,660
JBrowse link
G Dnase2b deoxyribonuclease II beta affects expression ISO theaflavin-3,3'-digallate affects the expression of DNASE2B mRNA CTD PMID:34925699 NCBI chr 3:146,275,488...146,322,815
Ensembl chr 3:146,286,740...146,321,351
JBrowse link
G Dok2 docking protein 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of DOK2 mRNA CTD PMID:34925699 NCBI chr14:71,003,336...71,015,934
Ensembl chr14:71,003,476...71,015,935
JBrowse link
G Dppa3 developmental pluripotency-associated 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of DPPA3 mRNA CTD PMID:34925699 NCBI chr 6:122,603,383...122,607,230
Ensembl chr 6:122,603,369...122,607,231
JBrowse link
G Dppa5a developmental pluripotency associated 5A affects expression ISO theaflavin-3,3'-digallate affects the expression of DPPA5 mRNA CTD PMID:34925699 NCBI chr 9:78,274,334...78,275,481
Ensembl chr 9:78,274,334...78,275,459
JBrowse link
G Drc7 dynein regulatory complex subunit 7 affects expression ISO theaflavin-3,3'-digallate affects the expression of DRC7 mRNA CTD PMID:34925699 NCBI chr 8:95,781,731...95,804,769
Ensembl chr 8:95,781,731...95,804,769
JBrowse link
G Dscaml1 DS cell adhesion molecule like 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of DSCAML1 mRNA CTD PMID:34925699 NCBI chr 9:45,338,735...45,665,011
Ensembl chr 9:45,337,926...45,665,010
JBrowse link
G Ebp EBP cholestenol delta-isomerase multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of EBP mRNA] CTD PMID:36105184 NCBI chr  X:8,051,568...8,059,751
Ensembl chr  X:8,051,568...8,059,751
JBrowse link
G Edn1 endothelin 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of EDN1 mRNA CTD PMID:34925699 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
JBrowse link
G Efnb1 ephrin B1 affects expression ISO theaflavin-3,3'-digallate affects the expression of EFNB1 mRNA CTD PMID:34925699 NCBI chr  X:98,179,667...98,192,628
Ensembl chr  X:98,179,736...98,192,597
JBrowse link
G Egf epidermal growth factor multiple interactions EXP
ISO
theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased phosphorylation of and results in increased activity of EGFR protein]; theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]
theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased activity of SP1 protein]; theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased expression of FAS mRNA]; theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased expression of FAS protein]; theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein]
CTD PMID:12931129 PMID:16353237 NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions EXP
ISO
theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased phosphorylation of and results in increased activity of EGFR protein]
theaflavin-3,3'-digallate results in increased ubiquitination of and results in increased degradation of and results in decreased expression of EGFR protein
[theaflavin co-treated with theaflavine gallate co-treated with theaflavin-3,3'-digallate] inhibits the reaction [Tobacco Smoke Pollution results in increased expression of and results in increased phosphorylation of EGFR protein]; [theaflavin co-treated with theaflavine gallate co-treated with theaflavin-3,3'-digallate] inhibits the reaction [Tobacco Smoke Pollution results in increased expression of EGFR mRNA]
CTD PMID:16353237 PMID:21475988 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of ELOVL1 mRNA] CTD PMID:36105184 NCBI chr 4:118,285,321...118,290,150
Ensembl chr 4:118,285,290...118,290,150
JBrowse link
G Epha8 Eph receptor A8 affects expression ISO theaflavin-3,3'-digallate affects the expression of EPHA8 mRNA CTD PMID:34925699 NCBI chr 4:136,656,729...136,684,170
Ensembl chr 4:136,656,730...136,684,127
JBrowse link
G Ermn ermin, ERM-like protein affects expression ISO theaflavin-3,3'-digallate affects the expression of ERMN mRNA CTD PMID:34925699 NCBI chr 2:57,874,920...57,942,962
Ensembl chr 2:57,935,125...57,942,876
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signalling 1 multiple interactions
decreases expression
ISO [Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased expression of ERN1 mRNA
theaflavin-3,3'-digallate results in decreased expression of ERN1 mRNA
CTD PMID:34350509 NCBI chr11:106,285,474...106,378,701
Ensembl chr11:106,285,476...106,378,678
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of ERRFI1 mRNA CTD PMID:34925699 NCBI chr 4:150,938,253...150,953,346
Ensembl chr 4:150,938,376...150,953,349
JBrowse link
G Evpl envoplakin affects expression ISO theaflavin-3,3'-digallate affects the expression of EVPL mRNA CTD PMID:34925699 NCBI chr11:116,111,385...116,128,983
Ensembl chr11:116,111,385...116,128,903
JBrowse link
G Ezhip EZH inhibitory protein affects expression ISO theaflavin-3,3'-digallate affects the expression of EZHIP mRNA CTD PMID:34925699 NCBI chr  X:5,993,272...5,995,474
Ensembl chr  X:5,993,273...5,995,473
JBrowse link
G F11 coagulation factor XI affects expression ISO theaflavin-3,3'-digallate affects the expression of F11 mRNA CTD PMID:34925699 NCBI chr 8:45,693,696...45,715,092
Ensembl chr 8:45,694,211...45,715,068
JBrowse link
G F13b coagulation factor XIII, beta subunit affects expression ISO theaflavin-3,3'-digallate affects the expression of F13B mRNA CTD PMID:34925699 NCBI chr 1:139,429,285...139,451,496
Ensembl chr 1:139,429,440...139,451,490
JBrowse link
G F2 coagulation factor II affects expression ISO theaflavin-3,3'-digallate affects the expression of F2 mRNA CTD PMID:34925699 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G F2rl3 F2R like thrombin or trypsin receptor 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of F2RL3 mRNA CTD PMID:34925699 NCBI chr 8:73,488,287...73,490,526
Ensembl chr 8:73,488,508...73,490,502
JBrowse link
G F3 coagulation factor III affects expression ISO theaflavin-3,3'-digallate affects the expression of F3 mRNA CTD PMID:34925699 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
JBrowse link
G Fabp12 fatty acid binding protein 12 affects expression ISO theaflavin-3,3'-digallate affects the expression of FABP12 mRNA CTD PMID:34925699 NCBI chr 3:10,309,269...10,366,575
Ensembl chr 3:10,309,269...10,366,243
JBrowse link
G Fabp4 fatty acid binding protein 4, adipocyte multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of FABP4 mRNA] CTD PMID:36105184 NCBI chr 3:10,269,406...10,273,653
Ensembl chr 3:10,269,148...10,273,636
JBrowse link
G Fads1 fatty acid desaturase 1 multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of FADS1 mRNA] CTD PMID:36105184 NCBI chr19:10,160,245...10,174,238
Ensembl chr19:10,160,252...10,174,241
JBrowse link
G Fam177b family with sequence similarity 177 member B affects expression ISO theaflavin-3,3'-digallate affects the expression of FAM177B mRNA CTD PMID:34925699 NCBI chr 1:183,010,580...183,057,296 JBrowse link
G Fam180a family with sequence similarity 180, member A affects expression ISO theaflavin-3,3'-digallate affects the expression of FAM180A mRNA CTD PMID:34925699 NCBI chr 6:35,289,678...35,303,076
Ensembl chr 6:35,289,603...35,303,076
JBrowse link
G Fam83c family with sequence similarity 83, member C affects expression ISO theaflavin-3,3'-digallate affects the expression of FAM83C mRNA CTD PMID:34925699 NCBI chr 2:155,671,103...155,676,772
Ensembl chr 2:155,669,468...155,676,774
JBrowse link
G Fas Fas cell surface death receptor multiple interactions
increases expression
ISO theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased expression of FAS mRNA]; theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased expression of FAS protein]
theaflavin-3,3'-digallate results in increased expression of FAS protein
CTD PMID:12931129 PMID:30769778 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fasl Fas ligand affects expression ISO theaflavin-3,3'-digallate affects the expression of FASLG mRNA CTD PMID:34925699 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
JBrowse link
G Fcamr Fc receptor, IgA, IgM, high affinity affects expression ISO theaflavin-3,3'-digallate affects the expression of FCAMR mRNA CTD PMID:34925699 NCBI chr 1:130,712,444...130,753,641
Ensembl chr 1:130,728,639...130,742,477
JBrowse link
G Fcna ficolin A affects expression ISO theaflavin-3,3'-digallate affects the expression of FCN3 mRNA CTD PMID:34925699 NCBI chr 2:25,514,677...25,525,448
Ensembl chr 2:25,514,678...25,518,042
JBrowse link
G Fcrl5 Fc receptor-like 5 affects expression ISO theaflavin-3,3'-digallate affects the expression of FCRL5 mRNA CTD PMID:34925699 NCBI chr 3:87,343,084...87,407,985
Ensembl chr 3:87,343,080...87,407,985
JBrowse link
G Fcrl6 Fc receptor-like 6 affects expression ISO theaflavin-3,3'-digallate affects the expression of FCRL6 mRNA CTD PMID:34925699 NCBI chr 1:172,423,081...172,445,889
Ensembl chr 1:172,424,209...172,430,118
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of FDFT1 mRNA] CTD PMID:36105184 NCBI chr14:63,382,599...63,419,136
Ensembl chr14:63,382,599...63,417,027
JBrowse link
G Fgd2 FYVE, RhoGEF and PH domain containing 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of FGD2 mRNA CTD PMID:34925699 NCBI chr17:29,579,878...29,598,509
Ensembl chr17:29,579,888...29,598,635
JBrowse link
G Fgf17 fibroblast growth factor 17 affects expression ISO theaflavin-3,3'-digallate affects the expression of FGF17 mRNA CTD PMID:34925699 NCBI chr14:70,873,643...70,880,064
Ensembl chr14:70,873,643...70,879,708
JBrowse link
G Fgf18 fibroblast growth factor 18 affects expression ISO theaflavin-3,3'-digallate affects the expression of FGF18 mRNA CTD PMID:34925699 NCBI chr11:33,066,970...33,097,400
Ensembl chr11:33,067,430...33,097,400
JBrowse link
G Fli1 Friend leukemia integration 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of FLI1 mRNA CTD PMID:34925699 NCBI chr 9:32,333,500...32,454,292
Ensembl chr 9:32,333,500...32,454,157
JBrowse link
G Fndc7 fibronectin type III domain containing 7 affects expression ISO theaflavin-3,3'-digallate affects the expression of FNDC7 mRNA CTD PMID:34925699 NCBI chr 3:108,760,898...108,797,324
Ensembl chr 3:108,760,994...108,797,324
JBrowse link
G Foxd3 forkhead box D3 affects expression ISO theaflavin-3,3'-digallate affects the expression of FOXD3 mRNA CTD PMID:34925699 NCBI chr 4:99,544,536...99,546,908
Ensembl chr 4:99,544,536...99,546,859
JBrowse link
G Foxd4 forkhead box D4 affects expression ISO theaflavin-3,3'-digallate affects the expression of FOXD4 mRNA CTD PMID:34925699 NCBI chr19:24,876,307...24,878,380
Ensembl chr19:24,876,600...24,878,561
JBrowse link
G Foxe3 forkhead box E3 affects expression ISO theaflavin-3,3'-digallate affects the expression of FOXE3 mRNA CTD PMID:34925699 NCBI chr 4:114,781,640...114,783,264
Ensembl chr 4:114,782,344...114,783,210
JBrowse link
G Foxg1 forkhead box G1 affects expression ISO theaflavin-3,3'-digallate affects the expression of FOXG1 mRNA CTD PMID:34925699 NCBI chr12:49,429,666...49,433,650
Ensembl chr12:49,429,443...49,433,644
JBrowse link
G Foxl1 forkhead box L1 affects expression ISO theaflavin-3,3'-digallate affects the expression of FOXL1 mRNA CTD PMID:34925699 NCBI chr 8:121,854,572...121,857,383
Ensembl chr 8:121,854,679...121,857,383
JBrowse link
G Foxq1 forkhead box Q1 affects expression ISO theaflavin-3,3'-digallate affects the expression of FOXQ1 mRNA CTD PMID:34925699 NCBI chr13:31,742,153...31,744,959
Ensembl chr13:31,740,117...31,744,959
JBrowse link
G Frmd7 FERM domain containing 7 affects expression ISO theaflavin-3,3'-digallate affects the expression of FRMD7 mRNA CTD PMID:34925699 NCBI chr  X:49,980,044...50,032,493
Ensembl chr  X:49,984,057...50,031,587
JBrowse link
G Frzb frizzled-related protein affects expression ISO theaflavin-3,3'-digallate affects the expression of FRZB mRNA CTD PMID:34925699 NCBI chr 2:80,242,314...80,277,740
Ensembl chr 2:80,242,314...80,277,969
JBrowse link
G Fscn3 fascin actin-bundling protein 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of FSCN3 mRNA CTD PMID:34925699 NCBI chr 6:28,427,888...28,438,621
Ensembl chr 6:28,427,788...28,438,621
JBrowse link
G Gabrr1 gamma-aminobutyric acid type A receptor subunit rho 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of GABRR1 mRNA CTD PMID:34925699 NCBI chr 4:33,132,556...33,163,606
Ensembl chr 4:33,132,521...33,163,588
JBrowse link
G Galnt14 polypeptide N-acetylgalactosaminyltransferase 14 affects expression ISO theaflavin-3,3'-digallate affects the expression of GALNT14 mRNA CTD PMID:34925699 NCBI chr17:73,800,202...74,019,138
Ensembl chr17:73,800,223...74,017,448
JBrowse link
G Garin1a golgi associated RAB2 interactor 1A affects expression ISO theaflavin-3,3'-digallate affects the expression of GARIN1A mRNA CTD PMID:34925699 NCBI chr 6:29,276,298...29,290,684
Ensembl chr 6:29,279,592...29,290,679
JBrowse link
G Garin4 golgi associated RAB2 interactor family member 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of GARIN4 mRNA CTD PMID:34925699 NCBI chr 1:190,894,781...190,897,014
Ensembl chr 1:190,894,781...190,897,014
JBrowse link
G Gdf9 growth differentiation factor 9 increases expression
affects expression
EXP
ISO
theaflavin-3,3'-digallate results in increased expression of GDF9 mRNA
theaflavin-3,3'-digallate affects the expression of GDF9 mRNA
CTD PMID:34925699 NCBI chr11:53,321,773...53,328,731
Ensembl chr11:53,321,850...53,328,731
JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of GDPD3 mRNA CTD PMID:34925699 NCBI chr 7:126,365,586...126,374,817
Ensembl chr 7:126,365,506...126,374,821
JBrowse link
G Gfi1b growth factor independent 1B affects expression ISO theaflavin-3,3'-digallate affects the expression of GFI1B mRNA CTD PMID:34925699 NCBI chr 2:28,499,462...28,511,994
Ensembl chr 2:28,499,462...28,511,994
JBrowse link
G Ghsr growth hormone secretagogue receptor affects expression ISO theaflavin-3,3'-digallate affects the expression of GHSR mRNA CTD PMID:34925699 NCBI chr 3:27,425,500...27,433,384
Ensembl chr 3:27,425,500...27,432,159
JBrowse link
G Gjb1 gap junction protein, beta 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of GJB1 mRNA CTD PMID:34925699 NCBI chr  X:100,419,982...100,429,235
Ensembl chr  X:100,419,984...100,429,235
JBrowse link
G Gjd4 gap junction protein, delta 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of GJD4 mRNA CTD PMID:34925699 NCBI chr18:9,278,124...9,289,808
Ensembl chr18:9,278,607...9,282,809
JBrowse link
G Glt1d1 glycosyltransferase 1 domain containing 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of GLT1D1 mRNA CTD PMID:34925699 NCBI chr 5:127,709,134...127,786,438
Ensembl chr 5:127,709,326...127,786,438
JBrowse link
G Gnat1 G protein subunit alpha transducin 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of GNAT1 mRNA CTD PMID:34925699 NCBI chr 9:107,551,636...107,556,833
Ensembl chr 9:107,551,673...107,556,911
JBrowse link
G Gp5 glycoprotein 5 platelet affects expression ISO theaflavin-3,3'-digallate affects the expression of GP5 mRNA CTD PMID:34925699 NCBI chr16:30,126,503...30,129,599
Ensembl chr16:30,126,503...30,129,597
JBrowse link
G Gpbar1 G protein-coupled bile acid receptor 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of GPBAR1 mRNA CTD PMID:34925699 NCBI chr 1:74,316,269...74,318,868
Ensembl chr 1:74,317,709...74,318,783
JBrowse link
G Gpr162 G protein-coupled receptor 162 affects expression ISO theaflavin-3,3'-digallate affects the expression of GPR162 mRNA CTD PMID:34925699 NCBI chr 6:124,835,407...124,840,900
Ensembl chr 6:124,835,407...124,840,946
JBrowse link
G Gpr19 G protein-coupled receptor 19 affects expression ISO theaflavin-3,3'-digallate affects the expression of GPR19 mRNA CTD PMID:34925699 NCBI chr 6:134,846,055...134,875,157
Ensembl chr 6:134,846,056...134,875,541
JBrowse link
G Gpr25 G protein-coupled receptor 25 affects expression ISO theaflavin-3,3'-digallate affects the expression of GPR25 mRNA CTD PMID:34925699 NCBI chr 1:136,186,652...136,188,664
Ensembl chr 1:136,187,535...136,188,611
JBrowse link
G Gpr82 G protein-coupled receptor 82 affects expression ISO theaflavin-3,3'-digallate affects the expression of GPR82 mRNA CTD PMID:34925699 NCBI chr  X:13,512,373...13,533,669
Ensembl chr  X:13,527,602...13,533,672
JBrowse link
G Gpr83 G protein-coupled receptor 83 affects expression ISO theaflavin-3,3'-digallate affects the expression of GPR83 mRNA CTD PMID:34925699 NCBI chr 9:14,771,038...14,782,085
Ensembl chr 9:14,771,506...14,782,085
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [Galactose results in decreased expression of GPX1 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in decreased expression of GPX1 mRNA] CTD PMID:32694992 PMID:36638877 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
JBrowse link
G Gria2 glutamate receptor, ionotropic, AMPA2 (alpha 2) affects expression ISO theaflavin-3,3'-digallate affects the expression of GRIA2 mRNA CTD PMID:34925699 NCBI chr 3:80,588,757...80,711,534
Ensembl chr 3:80,588,757...80,710,142
JBrowse link
G Gsdmc2 gasdermin C2 affects expression ISO theaflavin-3,3'-digallate affects the expression of GSDMC mRNA CTD PMID:34925699 NCBI chr15:63,696,177...63,717,042
Ensembl chr15:63,696,195...63,717,026
JBrowse link
G Gtpbp6 GTP binding protein 6 (putative) affects expression ISO theaflavin-3,3'-digallate affects the expression of GTPBP6 mRNA CTD PMID:34925699 NCBI chr 5:110,251,842...110,256,063
Ensembl chr 5:110,251,841...110,256,063
JBrowse link
G Gucy2c guanylate cyclase 2c affects expression ISO theaflavin-3,3'-digallate affects the expression of GUCY2C mRNA CTD PMID:34925699 NCBI chr 6:136,674,282...136,758,740
Ensembl chr 6:136,674,282...136,758,763
JBrowse link
G H1f8 H1.8 linker histone affects expression ISO theaflavin-3,3'-digallate affects the expression of H1FOO mRNA CTD PMID:34925699 NCBI chr 6:115,921,892...115,927,203
Ensembl chr 6:115,921,899...115,927,197
JBrowse link
G H2ax H2A.X variant histone decreases expression ISO theaflavin-3,3'-digallate results in decreased expression of H2AX protein CTD PMID:34925699 NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374
JBrowse link
G H3c14 H3 clustered histone 14 affects expression ISO theaflavin-3,3'-digallate affects the expression of H3C3 mRNA CTD PMID:34925699 NCBI chr 3:96,154,001...96,154,664
Ensembl chr 3:96,154,001...96,155,825
JBrowse link
G Hand1 heart and neural crest derivatives expressed 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of HAND1 mRNA CTD PMID:34925699 NCBI chr11:57,719,539...57,722,973
Ensembl chr11:57,719,531...57,723,644
JBrowse link
G Herpud1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of HERPUD1 mRNA CTD PMID:34925699 NCBI chr 8:95,113,057...95,121,999
Ensembl chr 8:95,113,066...95,122,005
JBrowse link
G Hes1 hes family bHLH transcription factor 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of HES1 mRNA CTD PMID:34925699 NCBI chr16:29,883,259...29,886,614
Ensembl chr16:29,883,202...29,886,614
JBrowse link
G Hey1 hairy/enhancer-of-split related with YRPW motif 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of HEY1 mRNA CTD PMID:34925699 NCBI chr 3:8,728,419...8,732,098
Ensembl chr 3:8,728,419...8,732,316
JBrowse link
G Hgd homogentisate 1, 2-dioxygenase affects expression ISO theaflavin-3,3'-digallate affects the expression of HGD mRNA CTD PMID:34925699 NCBI chr16:37,400,104...37,452,388
Ensembl chr16:37,400,515...37,452,382
JBrowse link
G Hhatl hedgehog acyltransferase-like affects expression ISO theaflavin-3,3'-digallate affects the expression of HHATL mRNA CTD PMID:34925699 NCBI chr 9:121,613,082...121,626,604
Ensembl chr 9:121,613,082...121,621,573
JBrowse link
G Hhipl2 hedgehog interacting protein-like 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of HHIPL2 mRNA CTD PMID:34925699 NCBI chr 1:183,195,395...183,217,962
Ensembl chr 1:183,199,147...183,217,717
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit decreases expression
multiple interactions
ISO theaflavin-3,3'-digallate results in decreased expression of HIF1A protein
[Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased expression of HIF1A protein
CTD PMID:34350509 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
EXP
ISO
theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in decreased expression of HMOX1 mRNA]
theaflavin-3,3'-digallate results in increased expression of HMOX1 protein
CTD PMID:32694992 PMID:35847580 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hmx1 H6 homeobox 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of HMX1 mRNA CTD PMID:34925699 NCBI chr 5:35,546,124...35,557,629
Ensembl chr 5:35,546,452...35,557,074
JBrowse link
G Hormad1 HORMA domain containing 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of HORMAD1 mRNA CTD PMID:34925699 NCBI chr 3:95,466,988...95,495,174
Ensembl chr 3:95,466,988...95,494,982
JBrowse link
G Hormad2 HORMA domain containing 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of HORMAD2 mRNA CTD PMID:34925699 NCBI chr11:4,295,801...4,391,215
Ensembl chr11:4,295,814...4,391,105
JBrowse link
G Hoxa10 homeobox A10 affects expression ISO theaflavin-3,3'-digallate affects the expression of HOXA10 mRNA CTD PMID:34925699 NCBI chr 6:52,208,177...52,217,658
Ensembl chr 6:52,208,177...52,217,834
JBrowse link
G Hoxc10 homeobox C10 affects expression ISO theaflavin-3,3'-digallate affects the expression of HOXC10 mRNA CTD PMID:34925699 NCBI chr15:102,875,231...102,880,333
Ensembl chr15:102,875,231...102,880,328
JBrowse link
G Hs3st5 heparan sulfate (glucosamine) 3-O-sulfotransferase 5 affects expression ISO theaflavin-3,3'-digallate affects the expression of HS3ST5 mRNA CTD PMID:34925699 NCBI chr10:36,382,794...36,710,393
Ensembl chr10:36,382,810...36,710,393
JBrowse link
G Hspa1a heat shock protein 1A multiple interactions
decreases expression
ISO [Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased expression of HSPA1A protein
theaflavin-3,3'-digallate results in decreased expression of HSPA1A protein
CTD PMID:34350509 NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132
JBrowse link
G Hspa5 heat shock protein 5 multiple interactions
decreases expression
ISO [Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased expression of HSPA5 protein
theaflavin-3,3'-digallate results in decreased expression of HSPA5 protein
CTD PMID:34350509 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
JBrowse link
G Hspa8 heat shock protein 8 affects expression ISO theaflavin-3,3'-digallate affects the expression of HSPA8 mRNA CTD PMID:34925699 NCBI chr 9:40,712,572...40,716,498
Ensembl chr 9:40,712,280...40,721,383
JBrowse link
G Htr1d 5-hydroxytryptamine (serotonin) receptor 1D affects expression ISO theaflavin-3,3'-digallate affects the expression of HTR1D mRNA CTD PMID:34925699 NCBI chr 4:136,150,835...136,171,716
Ensembl chr 4:136,150,835...136,171,709
JBrowse link
G Htr5a 5-hydroxytryptamine (serotonin) receptor 5A affects expression ISO theaflavin-3,3'-digallate affects the expression of HTR5A mRNA CTD PMID:34925699 NCBI chr 5:28,046,836...28,059,403
Ensembl chr 5:28,047,147...28,060,086
JBrowse link
G Hus1b HUS1 checkpoint clamp component B affects expression ISO theaflavin-3,3'-digallate affects the expression of HUS1B mRNA CTD PMID:34925699 NCBI chr13:31,130,559...31,131,744
Ensembl chr13:31,130,556...31,131,742
JBrowse link
G Id3 inhibitor of DNA binding 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of ID3 mRNA CTD PMID:34925699 NCBI chr 4:135,871,133...135,872,703
Ensembl chr 4:135,870,808...135,873,066
JBrowse link
G Ier5l immediate early response 5-like affects expression ISO theaflavin-3,3'-digallate affects the expression of IER5L mRNA CTD PMID:34925699 NCBI chr 2:30,362,643...30,364,211
Ensembl chr 2:30,361,549...30,364,231
JBrowse link
G Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of IGDCC3 mRNA CTD PMID:34925699 NCBI chr 9:65,048,404...65,094,313
Ensembl chr 9:65,048,471...65,093,154
JBrowse link
G Igkv8-24 immunoglobulin kappa chain variable 8-24 affects expression ISO theaflavin-3,3'-digallate affects the expression of EBLN1 mRNA CTD PMID:34925699 NCBI chr 6:70,193,842...70,194,405
Ensembl chr 6:70,193,842...70,194,405
JBrowse link
G Il10 interleukin 10 affects expression
multiple interactions
ISO
EXP
theaflavin-3,3'-digallate affects the expression of IL10 mRNA
theaflavin-3,3'-digallate results in increased expression of and results in increased secretion of IL10 protein
CTD PMID:33833684 PMID:34925699 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il13 interleukin 13 affects expression ISO theaflavin-3,3'-digallate affects the expression of IL13 mRNA CTD PMID:34925699 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
JBrowse link
G Il19 interleukin 19 affects expression ISO theaflavin-3,3'-digallate affects the expression of IL19 mRNA CTD PMID:34925699 NCBI chr 1:130,860,393...130,873,194
Ensembl chr 1:130,860,393...130,867,852
JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases secretion
EXP
ISO
theaflavin-3,3'-digallate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B mRNA]; theaflavin-3,3'-digallate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL1B protein]
theaflavin-3,3'-digallate results in decreased secretion of IL1B protein
theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of ACAN mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of ACAN protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of COL2A1 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of COL2A1 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of SOX9 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of SOX9 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased abundance of and results in increased secretion of Dinoprostone]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of ADAMTS5 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of ADAMTS5 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of IL6 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of MMP13 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of MMP3 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of NOS2 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of TNF mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of AKT1 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of and results in decreased expression of NFKBIA protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of MAPK1 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of MAPK3 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of RELA protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased secretion of IL1B protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased secretion of IL6 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased secretion of TNF protein]
CTD PMID:27871911 PMID:30874838 PMID:33833684 PMID:35847580 PMID:37651426 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il2 interleukin 2 decreases expression EXP theaflavin-3,3'-digallate results in decreased expression of IL2 mRNA CTD PMID:34925699 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
JBrowse link
G Il5ra interleukin 5 receptor, alpha affects expression ISO theaflavin-3,3'-digallate affects the expression of IL5RA mRNA CTD PMID:34925699 NCBI chr 6:106,687,336...106,725,998
Ensembl chr 6:106,687,318...106,725,998
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases secretion
EXP
ISO
theaflavin-3,3'-digallate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL6 protein]
theaflavin-3,3'-digallate results in decreased secretion of IL6 protein
theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of IL6 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased secretion of IL6 protein]
CTD PMID:27871911 PMID:30874838 PMID:33833684 PMID:35847580 PMID:37651426 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Inava innate immunity activator affects expression ISO theaflavin-3,3'-digallate affects the expression of INAVA mRNA CTD PMID:34925699 NCBI chr 1:136,141,259...136,162,045
Ensembl chr 1:136,141,269...136,162,002
JBrowse link
G Inhba inhibin beta-A affects expression ISO theaflavin-3,3'-digallate affects the expression of INHBA mRNA CTD PMID:34925699 NCBI chr13:16,178,841...16,206,194
Ensembl chr13:16,186,436...16,206,206
JBrowse link
G Insm2 insulinoma-associated 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of INSM2 mRNA CTD PMID:34925699 NCBI chr12:55,646,212...55,648,818
Ensembl chr12:55,646,212...55,648,871
JBrowse link
G Insyn2b inhibitory synaptic factor family member 2B affects expression ISO theaflavin-3,3'-digallate affects the expression of INSYN2B mRNA CTD PMID:34925699 NCBI chr11:34,264,822...34,372,642
Ensembl chr11:34,264,758...34,372,640
JBrowse link
G Iqcn IQ motif containing N affects expression ISO theaflavin-3,3'-digallate affects the expression of IQCN mRNA CTD PMID:34925699 NCBI chr 8:71,154,661...71,170,299
Ensembl chr 8:71,156,106...71,170,299
JBrowse link
G Iqub IQ motif and ubiquitin domain containing affects expression ISO theaflavin-3,3'-digallate affects the expression of IQUB mRNA CTD PMID:34925699 NCBI chr 6:24,444,864...24,515,066
Ensembl chr 6:24,444,864...24,515,066
JBrowse link
G Irgc immunity related GTPase cinema affects expression ISO theaflavin-3,3'-digallate affects the expression of IRGC mRNA CTD PMID:34925699 NCBI chr 7:24,131,344...24,145,107
Ensembl chr 7:24,131,347...24,151,722
JBrowse link
G Itga2b integrin alpha 2b affects expression ISO theaflavin-3,3'-digallate affects the expression of ITGA2B mRNA CTD PMID:34925699 NCBI chr11:102,344,134...102,360,570
Ensembl chr11:102,344,123...102,360,948
JBrowse link
G Itgb6 integrin beta 6 affects expression ISO theaflavin-3,3'-digallate affects the expression of ITGB6 mRNA CTD PMID:34925699 NCBI chr 2:60,428,636...60,553,005
Ensembl chr 2:60,428,636...60,552,987
JBrowse link
G Izumo1r IZUMO1 receptor, JUNO affects expression ISO theaflavin-3,3'-digallate affects the expression of IZUMO1R mRNA CTD PMID:34925699 NCBI chr 9:14,797,110...14,815,247
Ensembl chr 9:14,797,110...14,815,245
JBrowse link
G Jag2 jagged 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of JAG2 mRNA CTD PMID:34925699 NCBI chr12:112,871,439...112,893,437
Ensembl chr12:112,871,439...112,893,396
JBrowse link
G Jun jun proto-oncogene multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of JUN protein] CTD PMID:27871911 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Kcne3 potassium voltage-gated channel, Isk-related subfamily, gene 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of KCNE3 mRNA CTD PMID:34925699 NCBI chr 7:99,825,714...99,834,076
Ensembl chr 7:99,825,709...99,834,076
JBrowse link
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 affects expression ISO theaflavin-3,3'-digallate affects the expression of KCNJ6 mRNA CTD PMID:34925699 NCBI chr16:94,545,839...94,798,719
Ensembl chr16:94,549,495...94,798,560
JBrowse link
G Kcnk7 potassium channel, subfamily K, member 7 affects expression ISO theaflavin-3,3'-digallate affects the expression of KCNK7 mRNA CTD PMID:34925699 NCBI chr19:5,754,471...5,757,956
Ensembl chr19:5,754,395...5,757,137
JBrowse link
G Kcnt1 potassium channel, subfamily T, member 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of KCNT1 mRNA CTD PMID:34925699 NCBI chr 2:25,753,807...25,808,285
Ensembl chr 2:25,753,746...25,808,285
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase affects expression ISO theaflavin-3,3'-digallate affects the expression of KIT mRNA CTD PMID:34925699 NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382
JBrowse link
G Klk11 kallikrein related-peptidase 11 affects expression ISO theaflavin-3,3'-digallate affects the expression of KLK11 mRNA CTD PMID:34925699 NCBI chr 7:43,424,041...43,428,687
Ensembl chr 7:43,424,028...43,428,687
JBrowse link
G Klk14 kallikrein related-peptidase 14 affects expression ISO theaflavin-3,3'-digallate affects the expression of KLK14 mRNA CTD PMID:34925699 NCBI chr 7:43,330,305...43,344,960
Ensembl chr 7:43,339,842...43,344,960
JBrowse link
G Krt79 keratin 79 affects expression ISO theaflavin-3,3'-digallate affects the expression of KRT79 mRNA CTD PMID:34925699 NCBI chr15:101,837,767...101,848,759
Ensembl chr15:101,837,767...101,848,759
JBrowse link
G Lair1 leukocyte-associated Ig-like receptor 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of LAIR1 mRNA CTD PMID:34925699 NCBI chr 7:4,010,072...4,076,566
Ensembl chr 7:4,006,401...4,066,178
JBrowse link
G Lat2 linker for activation of T cells family, member 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of LAT2 mRNA CTD PMID:34925699 NCBI chr 5:134,628,957...134,648,637
Ensembl chr 5:134,628,876...134,643,879
JBrowse link
G Ldb2 LIM domain binding 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of LDB2 mRNA CTD PMID:34925699 NCBI chr 5:44,593,292...44,957,466
Ensembl chr 5:44,629,474...44,957,022
JBrowse link
G Ldhal6b lactate dehydrogenase A-like 6B affects expression ISO theaflavin-3,3'-digallate affects the expression of LDHAL6B mRNA CTD PMID:34925699 NCBI chr17:5,467,598...5,469,042
Ensembl chr17:5,467,598...5,469,042
JBrowse link
G Lep leptin multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of ACADM mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of CYP1A2 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of CYP2C70 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of CYP4F14 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of DHCR7 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of EBP mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of ELOVL1 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of FABP4 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of FADS1 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of FDFT1 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of LPL mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of PLIN4 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of PPARD mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of SCD1 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of TECR mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of TM7SF2 mRNA] CTD PMID:36105184 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
JBrowse link
G Lgr5 leucine rich repeat containing G protein coupled receptor 5 affects expression ISO theaflavin-3,3'-digallate affects the expression of LGR5 mRNA CTD PMID:34925699 NCBI chr10:115,286,219...115,423,685
Ensembl chr10:115,286,216...115,423,685
JBrowse link
G Lman1l lectin, mannose-binding 1 like affects expression ISO theaflavin-3,3'-digallate affects the expression of LMAN1L mRNA CTD PMID:34925699 NCBI chr 9:57,514,080...57,528,057
Ensembl chr 9:57,514,368...57,528,057
JBrowse link
G Lpl lipoprotein lipase multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of LPL mRNA] CTD PMID:36105184 NCBI chr 8:69,333,207...69,359,584
Ensembl chr 8:69,333,143...69,360,100
JBrowse link
G Lrp1b low density lipoprotein-related protein 1B affects expression ISO theaflavin-3,3'-digallate affects the expression of LRP1B mRNA CTD PMID:34925699 NCBI chr 2:40,485,302...42,543,747
Ensembl chr 2:40,485,258...42,543,636
JBrowse link
G Lrrc18 leucine rich repeat containing 18 affects expression ISO theaflavin-3,3'-digallate affects the expression of LRRC18 mRNA CTD PMID:34925699 NCBI chr14:32,713,339...32,737,257
Ensembl chr14:32,713,339...32,737,248
JBrowse link
G Lrrc66 leucine rich repeat containing 66 affects expression ISO theaflavin-3,3'-digallate affects the expression of LRRC66 mRNA CTD PMID:34925699 NCBI chr 5:73,763,985...73,789,771
Ensembl chr 5:73,763,985...73,789,869
JBrowse link
G Lsmem1 leucine-rich single-pass membrane protein 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of LSMEM1 mRNA CTD PMID:34925699 NCBI chr12:40,226,385...40,249,314
Ensembl chr12:40,225,492...40,249,489
JBrowse link
G Ly9 lymphocyte antigen 9 affects expression ISO theaflavin-3,3'-digallate affects the expression of LY9 mRNA CTD PMID:34925699 NCBI chr 1:171,416,172...171,434,917
Ensembl chr 1:171,416,192...171,434,978
JBrowse link
G Mab21l3 mab-21-like 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of MAB21L3 mRNA CTD PMID:34925699 NCBI chr 3:101,720,392...101,743,601
Ensembl chr 3:101,720,392...101,756,275
JBrowse link
G Mafb MAF bZIP transcription factor B affects expression ISO theaflavin-3,3'-digallate affects the expression of MAFB mRNA CTD PMID:34925699 NCBI chr 2:160,205,597...160,208,985
Ensembl chr 2:160,205,623...160,208,985
JBrowse link
G Malrd1 MAM and LDL receptor class A domain containing 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of MALRD1 mRNA CTD PMID:34925699 NCBI chr 2:15,531,290...16,260,368
Ensembl chr 2:15,531,290...16,260,366
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta decreases expression
multiple interactions
ISO theaflavin-3,3'-digallate results in decreased expression of MAP1LC3B protein
[Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased expression of MAP1LC3B protein
CTD PMID:34350509 NCBI chr 8:122,317,177...122,325,499
Ensembl chr 8:122,317,100...122,325,499
JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 decreases expression ISO theaflavin-3,3'-digallate results in decreased expression of MAP2K1 mRNA; theaflavin-3,3'-digallate results in decreased expression of MAP2K1 protein CTD PMID:32964953 NCBI chr 9:64,093,066...64,160,887
Ensembl chr 9:64,093,052...64,160,913
JBrowse link
G Map2k2 mitogen-activated protein kinase kinase 2 decreases expression ISO theaflavin-3,3'-digallate results in decreased expression of MAP2K2 mRNA; theaflavin-3,3'-digallate results in decreased expression of MAP2K2 protein CTD PMID:32964953 NCBI chr10:80,941,749...80,960,531
Ensembl chr10:80,941,749...80,969,809
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
decreases phosphorylation
decreases expression
ISO
EXP
theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of MAPK1 protein]; theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in increased phosphorylation of MAPK1 protein]
theaflavin-3,3'-digallate results in decreased phosphorylation of MAPK1 protein
theaflavin-3,3'-digallate results in decreased expression of MAPK1 mRNA; theaflavin-3,3'-digallate results in decreased expression of MAPK1 protein
theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased phosphorylation of MAPK1 protein]
CTD PMID:16353237 PMID:30874838 PMID:32694992 PMID:32964953 PMID:33833684 More... NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions
decreases phosphorylation
decreases expression
ISO
EXP
theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of MAPK3 protein]; theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in increased phosphorylation of MAPK3 protein]
theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased phosphorylation of MAPK3 protein]
theaflavin-3,3'-digallate results in decreased phosphorylation of MAPK3 protein
theaflavin-3,3'-digallate results in decreased expression of MAPK3 mRNA; theaflavin-3,3'-digallate results in decreased expression of MAPK3 protein
CTD PMID:16353237 PMID:30874838 PMID:32694992 PMID:32964953 PMID:33833684 More... NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 decreases phosphorylation
multiple interactions
EXP
ISO
theaflavin-3,3'-digallate results in decreased phosphorylation of MAPK8 protein
theaflavin-3,3'-digallate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK8 protein]
theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in increased phosphorylation of MAPK8 protein]
CTD PMID:27871911 PMID:32694992 PMID:35903325 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 decreases phosphorylation EXP theaflavin-3,3'-digallate results in decreased phosphorylation of MAPK9 protein CTD PMID:30874838 NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248
JBrowse link
G Matn4 matrilin 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of MATN4 mRNA CTD PMID:34925699 NCBI chr 2:164,231,313...164,247,080
Ensembl chr 2:164,231,313...164,247,080
JBrowse link
G Mep1b meprin 1 beta affects expression ISO theaflavin-3,3'-digallate affects the expression of MEP1B mRNA CTD PMID:34925699 NCBI chr18:21,205,401...21,233,256
Ensembl chr18:21,194,980...21,233,256
JBrowse link
G Mgam maltase-glucoamylase affects expression ISO theaflavin-3,3'-digallate affects the expression of MGAM mRNA CTD PMID:34925699 NCBI chr 6:40,605,765...40,746,057
Ensembl chr 6:40,605,765...40,746,057
JBrowse link
G Mia MIA SH3 domain containing affects expression ISO theaflavin-3,3'-digallate affects the expression of MIA mRNA CTD PMID:34925699 NCBI chr 7:26,879,166...26,880,574
Ensembl chr 7:26,879,167...26,880,582
JBrowse link
G Mkx mohawk homeobox affects expression ISO theaflavin-3,3'-digallate affects the expression of MKX mRNA CTD PMID:34925699 NCBI chr18:6,934,966...7,004,779
Ensembl chr18:6,934,518...7,004,780
JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of MMP13 protein] CTD PMID:35847580 NCBI chr 9:7,272,514...7,283,333
Ensembl chr 9:7,272,514...7,283,331
JBrowse link
G Mmp17 matrix metallopeptidase 17 affects expression ISO theaflavin-3,3'-digallate affects the expression of MMP17 mRNA CTD PMID:34925699 NCBI chr 5:129,661,215...129,688,163
Ensembl chr 5:129,661,233...129,688,163
JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) decreases expression EXP theaflavin-3,3'-digallate results in decreased expression of MMP1 protein CTD PMID:30874838 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression EXP theaflavin-3,3'-digallate results in decreased expression of MMP2 protein CTD PMID:30874838 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions
decreases expression
ISO
EXP
theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of MMP3 protein]
theaflavin-3,3'-digallate results in decreased expression of MMP3 protein
CTD PMID:30874838 PMID:35847580 NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in increased expression of MMP9 mRNA] CTD PMID:32694992 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Morn3 MORN repeat containing 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of MORN3 mRNA CTD PMID:34925699 NCBI chr 5:123,171,462...123,185,099
Ensembl chr 5:123,173,832...123,185,079
JBrowse link
G Mos Moloney sarcoma oncogene affects expression ISO theaflavin-3,3'-digallate affects the expression of MOS mRNA CTD PMID:34925699 NCBI chr 4:3,870,658...3,872,105
Ensembl chr 4:3,870,657...3,872,105
JBrowse link
G Mpl myeloproliferative leukemia virus oncogene affects expression ISO theaflavin-3,3'-digallate affects the expression of MPL mRNA CTD PMID:34925699 NCBI chr 4:118,299,609...118,314,771
Ensembl chr 4:118,299,612...118,314,710
JBrowse link
G Mpzl2 myelin protein zero-like 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of MPZL2 mRNA CTD PMID:34925699 NCBI chr 9:44,951,595...44,965,341
Ensembl chr 9:44,951,097...44,965,313
JBrowse link
G Mrap2 melanocortin 2 receptor accessory protein 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of MRAP2 mRNA CTD PMID:34925699 NCBI chr 9:87,026,293...87,066,104
Ensembl chr 9:87,026,359...87,066,098
JBrowse link
G Mroh2b maestro heat-like repeat family member 2B affects expression ISO theaflavin-3,3'-digallate affects the expression of MROH2B mRNA CTD PMID:34925699 NCBI chr15:4,927,697...4,991,689
Ensembl chr15:4,928,219...4,991,687
JBrowse link
G Ms4a5 membrane-spanning 4-domains, subfamily A, member 5 affects expression ISO theaflavin-3,3'-digallate affects the expression of MS4A5 mRNA CTD PMID:34925699 NCBI chr19:11,251,514...11,261,259
Ensembl chr19:11,250,602...11,261,237
JBrowse link
G Mtfr2 mitochondrial fission regulator 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of MTFR2 mRNA CTD PMID:34925699 NCBI chr10:20,223,491...20,237,415
Ensembl chr10:20,223,516...20,237,050
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in increased phosphorylation of MTOR protein] CTD PMID:35903325 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140
JBrowse link
G Muc13 mucin 13, epithelial transmembrane affects expression ISO theaflavin-3,3'-digallate affects the expression of MUC13 mRNA CTD PMID:34925699 NCBI chr16:33,614,407...33,640,299
Ensembl chr16:33,614,407...33,640,304
JBrowse link
G Muc5ac mucin 5, subtypes A and C, tracheobronchial/gastric multiple interactions ISO [theaflavin co-treated with theaflavine gallate co-treated with theaflavin-3,3'-digallate] inhibits the reaction [Tobacco Smoke Pollution results in increased expression of and results in increased phosphorylation of MUC5AC protein]; [theaflavin co-treated with theaflavine gallate co-treated with theaflavin-3,3'-digallate] inhibits the reaction [Tobacco Smoke Pollution results in increased expression of MUC5AC mRNA] CTD PMID:21475988 NCBI chr 7:141,342,695...141,372,964
Ensembl chr 7:141,342,709...141,372,968
JBrowse link
G Muc5b mucin 5, subtype B, tracheobronchial affects expression ISO theaflavin-3,3'-digallate affects the expression of MUC5B mRNA CTD PMID:34925699 NCBI chr 7:141,392,796...141,426,826
Ensembl chr 7:141,392,807...141,426,821
JBrowse link
G Myadml2 myeloid-associated differentiation marker-like 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of MYADML2 mRNA CTD PMID:34925699 NCBI chr11:120,536,857...120,539,188
Ensembl chr11:120,536,857...120,538,984
JBrowse link
G Mybphl myosin binding protein H-like affects expression ISO theaflavin-3,3'-digallate affects the expression of MYBPHL mRNA CTD PMID:34925699 NCBI chr 3:108,272,227...108,287,373
Ensembl chr 3:108,272,227...108,287,373
JBrowse link
G Myh11 myosin, heavy polypeptide 11, smooth muscle multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in decreased expression of MYH11 protein] CTD PMID:35903325 NCBI chr16:14,012,392...14,109,227
Ensembl chr16:14,012,399...14,109,236
JBrowse link
G Mylk3 myosin light chain kinase 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of MYLK3 mRNA CTD PMID:34925699 NCBI chr 8:86,050,933...86,112,969
Ensembl chr 8:86,050,932...86,112,974
JBrowse link
G Myo1a myosin IA affects expression ISO theaflavin-3,3'-digallate affects the expression of MYO1A mRNA CTD PMID:34925699 NCBI chr10:127,539,306...127,556,809
Ensembl chr10:127,541,039...127,556,809
JBrowse link
G Myo1f myosin IF affects expression ISO theaflavin-3,3'-digallate affects the expression of MYO1F mRNA CTD PMID:34925699 NCBI chr17:33,774,681...33,826,738
Ensembl chr17:33,774,681...33,826,738
JBrowse link
G Myod1 myogenic differentiation 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of MYOD1 mRNA CTD PMID:34925699 NCBI chr 7:46,025,898...46,028,516
Ensembl chr 7:46,025,898...46,028,523
JBrowse link
G Nalf2 NALCN channel auxiliary factor 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of NALF2 mRNA CTD PMID:34925699 NCBI chr  X:98,863,770...98,892,395
Ensembl chr  X:98,864,627...98,892,396
JBrowse link
G Ncf4 neutrophil cytosolic factor 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of NCF4 mRNA CTD PMID:34925699 NCBI chr15:78,128,324...78,146,782
Ensembl chr15:78,129,001...78,146,780
JBrowse link
G Nckap1l NCK associated protein 1 like affects expression ISO theaflavin-3,3'-digallate affects the expression of NCKAP1L mRNA CTD PMID:34925699 NCBI chr15:103,362,219...103,411,288
Ensembl chr15:103,362,221...103,407,237
JBrowse link
G Neurog2 neurogenin 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of NEUROG2 mRNA CTD PMID:34925699 NCBI chr 3:127,426,382...127,429,285
Ensembl chr 3:127,426,784...127,429,280
JBrowse link
G Nfatc3 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3 multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in decreased phosphorylation of NFATC3 protein] CTD PMID:35406003 NCBI chr 8:106,785,450...106,857,169
Ensembl chr 8:106,785,472...106,857,169
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions
increases expression
ISO
EXP
theaflavin-3,3'-digallate results in increased expression of and affects the localization of NFE2L2 protein
theaflavin-3,3'-digallate results in increased expression of NFE2L2 protein
[theaflavin-3,3'-digallate results in increased expression of NFE2L2 protein] inhibits the reaction [TNFSF11 protein results in increased abundance of Reactive Oxygen Species]; [theaflavin-3,3'-digallate results in increased expression of NFE2L2 protein] which results in decreased abundance of Reactive Oxygen Species; theaflavin-3,3'-digallate inhibits the reaction [Galactose results in decreased expression of NFE2L2 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in decreased expression of NFE2L2 mRNA]; theaflavin-3,3'-digallate results in increased expression of and affects the localization of NFE2L2 protein
CTD PMID:32694992 PMID:35847580 PMID:36638877 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of and results in decreased expression of NFKBIA protein] CTD PMID:35847580 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Nkain3 Na+/K+ transporting ATPase interacting 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of NKAIN3 mRNA CTD PMID:34925699 NCBI chr 4:20,111,029...20,779,990
Ensembl chr 4:20,118,874...20,778,866
JBrowse link
G Nkx3-2 NK3 homeobox 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of NKX3-2 mRNA CTD PMID:34925699 NCBI chr 5:41,918,826...41,921,563
Ensembl chr 5:41,918,826...41,921,844
JBrowse link
G Nlrp4c NLR family, pyrin domain containing 4C affects expression ISO theaflavin-3,3'-digallate affects the expression of NLRP4 mRNA CTD PMID:34925699 NCBI chr 7:6,048,160...6,108,148
Ensembl chr 7:6,048,160...6,108,149
JBrowse link
G Nlrp5 NLR family, pyrin domain containing 5 affects expression ISO theaflavin-3,3'-digallate affects the expression of NLRP5 mRNA CTD PMID:34925699 NCBI chr 7:23,085,314...23,141,348
Ensembl chr 7:23,085,314...23,141,347
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of NOS2 protein] CTD PMID:35847580 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Notum notum palmitoleoyl-protein carboxylesterase affects expression ISO theaflavin-3,3'-digallate affects the expression of NOTUM mRNA CTD PMID:34925699 NCBI chr11:120,544,614...120,552,019
Ensembl chr11:120,544,614...120,552,001
JBrowse link
G Nova2 NOVA alternative splicing regulator 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of NOVA2 mRNA CTD PMID:34925699 NCBI chr 7:18,659,319...18,699,244
Ensembl chr 7:18,659,813...18,699,244
JBrowse link
G Nppa natriuretic peptide type A multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in increased expression of ANP mRNA] CTD PMID:35406003 NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536
JBrowse link
G Nppb natriuretic peptide type B multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in increased expression of BNP mRNA] CTD PMID:35406003 NCBI chr 4:148,070,264...148,071,662
Ensembl chr 4:148,070,245...148,071,662
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of NR4A2 mRNA CTD PMID:34925699 NCBI chr 2:56,996,845...57,014,152
Ensembl chr 2:56,996,842...57,014,015
JBrowse link
G Nrg1 neuregulin 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of NRG1 mRNA CTD PMID:34925699 NCBI chr 8:32,299,493...33,381,858
Ensembl chr 8:32,304,579...33,374,825
Ensembl chr 8:32,304,579...33,374,825
JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of NUSAP1 mRNA CTD PMID:34925699 NCBI chr 2:119,449,205...119,480,646
Ensembl chr 2:119,448,779...119,481,725
JBrowse link
G Nxf2 nuclear RNA export factor 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of NXF5 mRNA CTD PMID:34925699 NCBI chr  X:133,845,275...133,865,503
Ensembl chr  X:133,845,275...133,865,503
JBrowse link
G Olig1 oligodendrocyte transcription factor 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of OLIG1 mRNA CTD PMID:34925699 NCBI chr16:91,066,657...91,068,827
Ensembl chr16:91,066,660...91,068,821
JBrowse link
G Omg oligodendrocyte myelin glycoprotein affects expression ISO theaflavin-3,3'-digallate affects the expression of OMG mRNA CTD PMID:34925699 NCBI chr11:79,391,808...79,394,908
Ensembl chr11:79,391,808...79,394,910
JBrowse link
G Opn1sw opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan) affects expression ISO theaflavin-3,3'-digallate affects the expression of OPN1SW mRNA CTD PMID:34925699 NCBI chr 6:29,376,670...29,380,512
Ensembl chr 6:29,376,670...29,388,467
JBrowse link
G Or2a25 olfactory receptor family 2 subfamily A member 25 affects expression ISO theaflavin-3,3'-digallate affects the expression of OR2A25 mRNA CTD PMID:34925699 NCBI chr 6:42,888,459...42,889,391
Ensembl chr 6:42,885,812...42,891,207
JBrowse link
G Or2k2 olfactory receptor family 2 subfamily K member 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of OR2K2 mRNA CTD PMID:34925699 NCBI chr 4:58,784,779...58,785,720
Ensembl chr 4:58,782,704...58,787,716
JBrowse link
G Or3a1d olfactory receptor family 3 subfamily A member 1D affects expression ISO theaflavin-3,3'-digallate affects the expression of OR3A3 mRNA CTD PMID:34925699 NCBI chr11:74,237,450...74,238,498
Ensembl chr11:74,235,955...74,243,476
JBrowse link
G Or51i1 olfactory receptor family 51 subfamily I member 1D affects expression ISO theaflavin-3,3'-digallate affects the expression of OR51I1 mRNA CTD PMID:34925699 NCBI chr 7:103,670,579...103,671,523
Ensembl chr 7:103,667,893...103,674,780
JBrowse link
G Or5b99 olfactory receptor family 5 subfamily B member 99 affects expression ISO theaflavin-3,3'-digallate affects the expression of OR5B2 mRNA CTD PMID:34925699 NCBI chr19:12,976,352...12,977,284
Ensembl chr19:12,972,378...12,977,781
JBrowse link
G Orm2 orosomucoid 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of ORM2 mRNA CTD PMID:34925699 NCBI chr 4:63,280,543...63,284,114
Ensembl chr 4:63,280,686...63,284,115
JBrowse link
G Otol1 otolin 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of OTOL1 mRNA CTD PMID:34925699 NCBI chr 3:69,914,946...69,936,041
Ensembl chr 3:69,914,946...69,936,041
JBrowse link
G Otor otoraplin affects expression ISO theaflavin-3,3'-digallate affects the expression of OTOR mRNA CTD PMID:34925699 NCBI chr 2:142,920,313...142,923,633
Ensembl chr 2:142,920,393...142,923,633
JBrowse link
G Otp orthopedia homeobox affects expression ISO theaflavin-3,3'-digallate affects the expression of OTP mRNA CTD PMID:34925699 NCBI chr13:95,012,144...95,021,633
Ensembl chr13:95,012,110...95,021,638
JBrowse link
G Otx2 orthodenticle homeobox 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of OTX2 mRNA CTD PMID:34925699 NCBI chr14:48,894,238...48,905,101
Ensembl chr14:48,895,134...48,911,276
JBrowse link
G Padi6 peptidyl arginine deiminase, type VI affects expression ISO theaflavin-3,3'-digallate affects the expression of PADI6 mRNA CTD PMID:34925699 NCBI chr 4:140,454,666...140,469,954
Ensembl chr 4:140,454,666...140,469,954
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 increases cleavage ISO theaflavin-3,3'-digallate results in increased cleavage of PARP1 protein CTD PMID:30769778 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Pate1 prostate and testis expressed 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of PATE1 mRNA CTD PMID:34925699 NCBI chr 9:35,596,182...35,598,686
Ensembl chr 9:35,596,375...35,598,686
JBrowse link
G Pax3 paired box 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of PAX3 mRNA CTD PMID:34925699 NCBI chr 1:78,077,904...78,173,773
Ensembl chr 1:78,077,904...78,173,771
JBrowse link
G Pbx4 pre B cell leukemia homeobox 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of PBX4 mRNA CTD PMID:34925699 NCBI chr 8:70,285,127...70,324,942
Ensembl chr 8:70,285,141...70,324,942
JBrowse link
G Pcdha5 protocadherin alpha 5 affects expression ISO theaflavin-3,3'-digallate affects the expression of PCDHA5 mRNA CTD PMID:34925699 NCBI chr18:37,093,329...37,320,716
Ensembl chr18:37,093,493...37,320,710
JBrowse link
G Pcp4l1 Purkinje cell protein 4-like 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of PCP4L1 mRNA CTD PMID:34925699 NCBI chr 1:171,000,833...171,023,837
Ensembl chr 1:171,000,831...171,023,837
JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of PCSK2 mRNA CTD PMID:34925699 NCBI chr 2:143,388,053...143,658,204
Ensembl chr 2:143,388,076...143,658,205
JBrowse link
G Pde2a phosphodiesterase 2A, cGMP-stimulated affects expression ISO theaflavin-3,3'-digallate affects the expression of PDE2A mRNA CTD PMID:34925699 NCBI chr 7:101,070,905...101,162,026
Ensembl chr 7:101,060,093...101,162,026
Ensembl chr 7:101,060,093...101,162,026
JBrowse link
G Pde3a phosphodiesterase 3A, cGMP inhibited affects expression ISO theaflavin-3,3'-digallate affects the expression of PDE3A mRNA CTD PMID:34925699 NCBI chr 6:141,194,995...141,452,588
Ensembl chr 6:141,194,995...141,453,174
JBrowse link
G Pdgfrb platelet derived growth factor receptor, beta polypeptide multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in increased phosphorylation of PDGFRB protein] CTD PMID:35903325 NCBI chr18:61,178,194...61,218,139
Ensembl chr18:61,178,222...61,218,133
JBrowse link
G Pex5l peroxisomal biogenesis factor 5-like affects expression ISO theaflavin-3,3'-digallate affects the expression of PEX5L mRNA CTD PMID:34925699 NCBI chr 3:33,002,075...33,197,470
Ensembl chr 3:33,003,557...33,197,396
JBrowse link
G Pgcka1 PDCD10 and GCKIII kinases associated 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of PGCKA1 mRNA CTD PMID:34925699 NCBI chr 5:63,969,833...64,056,968
Ensembl chr 5:63,969,706...64,056,968
JBrowse link
G Phospho1 phosphatase, orphan 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of PHOSPHO1 mRNA CTD PMID:34925699 NCBI chr11:95,715,326...95,722,966
Ensembl chr11:95,715,325...95,722,966
JBrowse link
G Pkd1l1 polycystic kidney disease 1 like 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of PKD1L1 mRNA CTD PMID:34925699 NCBI chr11:8,782,025...8,924,365
Ensembl chr11:8,776,708...8,938,709
JBrowse link
G Pkd1l3 polycystic kidney disease 1 like 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of PKD1L3 mRNA CTD PMID:34925699 NCBI chr 8:110,340,828...110,399,305
Ensembl chr 8:110,341,149...110,401,018
JBrowse link
G Pkdrej polycystin (PKD) family receptor for egg jelly affects expression ISO theaflavin-3,3'-digallate affects the expression of PKDREJ mRNA CTD PMID:34925699 NCBI chr15:85,698,877...85,705,934
Ensembl chr15:85,698,871...85,705,935
JBrowse link
G Pla2g12b phospholipase A2, group XIIB affects expression ISO theaflavin-3,3'-digallate affects the expression of PLA2G12B mRNA CTD PMID:34925699 NCBI chr10:59,239,242...59,257,798
Ensembl chr10:59,239,482...59,257,798
JBrowse link
G Pla2g2f phospholipase A2, group IIF affects expression ISO theaflavin-3,3'-digallate affects the expression of PLA2G2F mRNA CTD PMID:34925699 NCBI chr 4:138,477,842...138,484,932
Ensembl chr 4:138,477,844...138,484,937
JBrowse link
G Plcg1 phospholipase C, gamma 1 multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in increased phosphorylation of PLCG1 protein] CTD PMID:35903325 NCBI chr 2:160,573,230...160,617,680
Ensembl chr 2:160,573,220...160,617,680
JBrowse link
G Plekha6 pleckstrin homology domain containing, family A member 6 affects expression ISO theaflavin-3,3'-digallate affects the expression of PLEKHA6 mRNA CTD PMID:34925699 NCBI chr 1:133,089,770...133,231,173
Ensembl chr 1:133,091,948...133,231,173
JBrowse link
G Plin1 perilipin 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of PLIN1 mRNA CTD PMID:34925699 NCBI chr 7:79,370,912...79,382,652
Ensembl chr 7:79,369,966...79,382,651
JBrowse link
G Plin4 perilipin 4 multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of PLIN4 mRNA] CTD PMID:36105184 NCBI chr17:56,407,587...56,416,947
Ensembl chr17:56,407,591...56,416,803
JBrowse link
G Plpp2 phospholipid phosphatase 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of PLPP2 mRNA CTD PMID:34925699 NCBI chr10:79,362,258...79,369,621
Ensembl chr10:79,362,264...79,369,630
JBrowse link
G Pmp2 peripheral myelin protein 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of PMP2 mRNA CTD PMID:34925699 NCBI chr 3:10,244,911...10,248,945
Ensembl chr 3:10,244,911...10,248,989
JBrowse link
G Ppard peroxisome proliferator activator receptor delta multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of PPARD mRNA] CTD PMID:36105184 NCBI chr17:28,451,715...28,520,446
Ensembl chr17:28,451,674...28,520,448
JBrowse link
G Ppef2 protein phosphatase, EF hand calcium-binding domain 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of PPEF2 mRNA CTD PMID:34925699 NCBI chr 5:92,374,109...92,404,759
Ensembl chr 5:92,374,538...92,404,137
JBrowse link
G Ppp3ca protein phosphatase 3, catalytic subunit, alpha isoform multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in increased expression of PPP3CA protein] CTD PMID:35406003 NCBI chr 3:136,375,778...136,643,488
Ensembl chr 3:136,375,885...136,643,488
JBrowse link
G Prap1 proline-rich acidic protein 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of PRAP1 mRNA CTD PMID:34925699 NCBI chr 7:139,673,309...139,677,116
Ensembl chr 7:139,673,308...139,677,113
JBrowse link
G Prdx2 peroxiredoxin 2 multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [Galactose results in decreased expression of PRDX2 mRNA] CTD PMID:36638877 NCBI chr 8:85,696,251...85,701,440
Ensembl chr 8:85,696,216...85,701,463
JBrowse link
G Prkag3 protein kinase, AMP-activated, gamma 3 non-catalytic subunit affects expression ISO theaflavin-3,3'-digallate affects the expression of PRKAG3 mRNA CTD PMID:34925699 NCBI chr 1:74,778,062...74,788,623
Ensembl chr 1:74,778,081...74,788,380
JBrowse link
G Prokr1 prokineticin receptor 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of PROKR1 mRNA CTD PMID:34925699 NCBI chr 6:87,555,568...87,567,741
Ensembl chr 6:87,555,573...87,567,725
JBrowse link
G Proz protein Z, vitamin K-dependent plasma glycoprotein affects expression ISO theaflavin-3,3'-digallate affects the expression of PROZ mRNA CTD PMID:34925699 NCBI chr 8:13,110,583...13,126,026
Ensembl chr 8:13,110,914...13,126,026
JBrowse link
G Ptcra pre T cell antigen receptor alpha affects expression ISO theaflavin-3,3'-digallate affects the expression of PTCRA mRNA CTD PMID:34925699 NCBI chr17:47,066,589...47,074,659
Ensembl chr17:47,066,589...47,074,638
JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of PTGDR2 mRNA CTD PMID:34925699 NCBI chr19:10,901,883...10,919,875
Ensembl chr19:10,914,524...10,919,875
JBrowse link
G Ptgir prostaglandin I receptor (IP) affects expression ISO theaflavin-3,3'-digallate affects the expression of PTGIR mRNA CTD PMID:34925699 NCBI chr 7:16,640,442...16,644,828
Ensembl chr 7:16,640,415...16,644,830
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein] CTD PMID:35847580 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Pygm muscle glycogen phosphorylase affects expression ISO theaflavin-3,3'-digallate affects the expression of PYGM mRNA CTD PMID:34925699 NCBI chr19:6,434,438...6,448,494
Ensembl chr19:6,434,429...6,448,489
JBrowse link
G Pyy peptide YY affects expression ISO theaflavin-3,3'-digallate affects the expression of PYY mRNA CTD PMID:34925699 NCBI chr11:101,997,502...101,998,658
Ensembl chr11:101,997,502...101,998,658
JBrowse link
G Rab39 RAB39, member RAS oncogene family affects expression ISO theaflavin-3,3'-digallate affects the expression of RAB39A mRNA CTD PMID:34925699 NCBI chr 9:53,595,410...53,617,532
Ensembl chr 9:53,595,410...53,617,532
JBrowse link
G Rab44 RAB44, member RAS oncogene family affects expression ISO theaflavin-3,3'-digallate affects the expression of RAB44 mRNA CTD PMID:34925699 NCBI chr17:29,333,102...29,367,966
Ensembl chr17:29,333,119...29,367,954
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions ISO CDKN1B promotes the reaction [theaflavin-3,3'-digallate results in decreased expression of and results in decreased phosphorylation of RB1 protein]; theaflavin-3,3'-digallate results in decreased expression of and results in decreased phosphorylation of RB1 protein CTD PMID:30769778 NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262
JBrowse link
G Rbfox3 RNA binding protein, fox-1 homolog (C. elegans) 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of RBFOX3 mRNA CTD PMID:34925699 NCBI chr11:118,380,586...118,802,423
Ensembl chr11:118,380,588...118,802,423
JBrowse link
G Rbp7 retinol binding protein 7, cellular affects expression ISO theaflavin-3,3'-digallate affects the expression of RBP7 mRNA CTD PMID:34925699 NCBI chr 4:149,534,144...149,550,919
Ensembl chr 4:149,534,144...149,539,435
JBrowse link
G Rcan2 regulator of calcineurin 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of RCAN2 mRNA CTD PMID:34925699 NCBI chr17:44,112,243...44,350,407
Ensembl chr17:44,112,242...44,350,407
JBrowse link
G Rcvrn recoverin affects expression ISO theaflavin-3,3'-digallate affects the expression of RCVRN mRNA CTD PMID:34925699 NCBI chr11:67,586,152...67,594,181
Ensembl chr11:67,586,152...67,594,159
JBrowse link
G Rd3 retinal degeneration 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of RD3 mRNA CTD PMID:34925699 NCBI chr 1:191,688,574...191,725,497
Ensembl chr 1:191,709,331...191,720,244
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO
EXP
theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of RELA protein]
theaflavin-3,3'-digallate inhibits the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of RELA protein]; theaflavin-3,3'-digallate results in decreased expression of and affects the localization of RELA protein
CTD PMID:27871911 PMID:30874838 PMID:35847580 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Retn resistin multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [Methylmercury Compounds results in increased secretion of RETN protein] CTD PMID:31195622 NCBI chr 8:3,705,770...3,709,818
Ensembl chr 8:3,705,770...3,710,110
JBrowse link
G Rfx6 regulatory factor X, 6 affects expression ISO theaflavin-3,3'-digallate affects the expression of RFX6 mRNA CTD PMID:34925699 NCBI chr10:51,553,856...51,606,525
Ensembl chr10:51,553,852...51,606,528
JBrowse link
G Rgs18 regulator of G-protein signaling 18 affects expression ISO theaflavin-3,3'-digallate affects the expression of RGS18 mRNA CTD PMID:34925699 NCBI chr 1:144,628,430...144,651,165
Ensembl chr 1:144,628,421...144,651,173
JBrowse link
G Rhoh ras homolog family member H affects expression ISO theaflavin-3,3'-digallate affects the expression of RHOH mRNA CTD PMID:34925699 NCBI chr 5:66,018,092...66,054,043
Ensembl chr 5:66,018,556...66,054,043
JBrowse link
G Rnf152 ring finger protein 152 affects expression ISO theaflavin-3,3'-digallate affects the expression of RNF152 mRNA CTD PMID:34925699 NCBI chr 1:105,204,642...105,284,665
Ensembl chr 1:105,204,639...105,284,435
JBrowse link
G Rspo1 R-spondin 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of RSPO1 mRNA CTD PMID:34925699 NCBI chr 4:124,880,197...124,902,895
Ensembl chr 4:124,880,223...124,902,892
JBrowse link
G Rspo2 R-spondin 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of RSPO2 mRNA CTD PMID:34925699 NCBI chr15:42,884,184...43,034,990
Ensembl chr15:42,884,190...43,034,222
JBrowse link
G Runx2 runt related transcription factor 2 multiple interactions
increases expression
EXP theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased expression of RUNX2 protein]
theaflavin-3,3'-digallate results in increased expression of RUNX2 protein
CTD PMID:33833684 NCBI chr17:44,806,873...45,125,518
Ensembl chr17:44,806,874...45,125,684
JBrowse link
G Scd1 stearoyl-Coenzyme A desaturase 1 multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of SCD1 mRNA] CTD PMID:36105184 NCBI chr19:44,382,889...44,396,148
Ensembl chr19:44,382,894...44,396,318
JBrowse link
G Scnn1b sodium channel, nonvoltage-gated 1 beta affects expression ISO theaflavin-3,3'-digallate affects the expression of SCNN1B mRNA CTD PMID:34925699 NCBI chr 7:121,464,261...121,517,951
Ensembl chr 7:121,464,261...121,517,737
JBrowse link
G Scx scleraxis scleraxis bHLH transcription factor affects expression ISO theaflavin-3,3'-digallate affects the expression of SCX mRNA CTD PMID:34925699 NCBI chr15:76,341,594...76,343,668
Ensembl chr15:76,341,652...76,343,658
JBrowse link
G Sdr42e1 short chain dehydrogenase/reductase family 42E, member 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of SDR42E1 mRNA CTD PMID:34925699 NCBI chr 8:118,388,138...118,400,428
Ensembl chr 8:118,388,138...118,400,428
JBrowse link
G Selp selectin, platelet affects expression ISO theaflavin-3,3'-digallate affects the expression of SELP mRNA CTD PMID:34925699 NCBI chr 1:163,942,833...163,977,595
Ensembl chr 1:163,942,833...163,977,595
JBrowse link
G Selplg selectin, platelet (p-selectin) ligand affects expression ISO theaflavin-3,3'-digallate affects the expression of SELPLG mRNA CTD PMID:34925699 NCBI chr 5:113,955,859...113,970,576
Ensembl chr 5:113,956,597...113,970,705
JBrowse link
G Serinc4 serine incorporator 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of SERINC4 mRNA CTD PMID:34925699 NCBI chr 2:121,281,658...121,287,245
Ensembl chr 2:121,269,540...121,287,262
JBrowse link
G Serpina6 serine (or cysteine) peptidase inhibitor, clade A, member 6 affects expression ISO theaflavin-3,3'-digallate affects the expression of SERPINA6 mRNA CTD PMID:34925699 NCBI chr12:103,612,889...103,623,477
Ensembl chr12:103,612,889...103,623,471
JBrowse link
G Serpinb10 serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10 affects expression ISO theaflavin-3,3'-digallate affects the expression of SERPINB10 mRNA CTD PMID:34925699 NCBI chr 1:107,456,724...107,488,469
Ensembl chr 1:107,456,757...107,477,001
JBrowse link
G Serpinb5 serine (or cysteine) peptidase inhibitor, clade B, member 5 affects expression ISO theaflavin-3,3'-digallate affects the expression of SERPINB5 mRNA CTD PMID:34925699 NCBI chr 1:106,788,905...106,811,078
Ensembl chr 1:106,788,903...106,811,078
JBrowse link
G Serpinc1 serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of SERPINC1 mRNA CTD PMID:34925699 NCBI chr 1:160,806,153...160,830,113
Ensembl chr 1:160,806,155...160,833,433
JBrowse link
G Sfn stratifin affects expression ISO theaflavin-3,3'-digallate affects the expression of SFN mRNA CTD PMID:34925699 NCBI chr 4:133,327,867...133,329,163
Ensembl chr 4:133,327,867...133,329,479
JBrowse link
G Sh2d4b SH2 domain containing 4B affects expression ISO theaflavin-3,3'-digallate affects the expression of SH2D4B mRNA CTD PMID:34925699 NCBI chr14:40,533,478...40,624,294
Ensembl chr14:40,535,746...40,615,223
JBrowse link
G Sh2d7 SH2 domain containing 7 affects expression ISO theaflavin-3,3'-digallate affects the expression of SH2D7 mRNA CTD PMID:34925699 NCBI chr 9:54,441,407...54,452,314
Ensembl chr 9:54,441,430...54,452,304
JBrowse link
G Siglec1 sialic acid binding Ig-like lectin 1, sialoadhesin affects expression ISO theaflavin-3,3'-digallate affects the expression of SIGLEC1 mRNA CTD PMID:34925699 NCBI chr 2:130,911,140...130,928,697
Ensembl chr 2:130,911,140...130,928,685
JBrowse link
G Slamf8 SLAM family member 8 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLAMF8 mRNA CTD PMID:34925699 NCBI chr 1:172,408,944...172,418,482
Ensembl chr 1:172,409,325...172,418,135
JBrowse link
G Slc10a6 solute carrier family 10 (sodium/bile acid cotransporter family), member 6 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLC10A6 mRNA CTD PMID:34925699 NCBI chr 5:103,753,583...103,777,152
Ensembl chr 5:103,753,577...103,777,269
JBrowse link
G Slc17a8 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLC17A8 mRNA CTD PMID:34925699 NCBI chr10:89,409,882...89,457,111
Ensembl chr10:89,409,882...89,457,115
JBrowse link
G Slc20a1 solute carrier family 20, member 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLC20A1 mRNA CTD PMID:34925699 NCBI chr 2:129,038,662...129,053,535
Ensembl chr 2:129,040,684...129,053,536
JBrowse link
G Slc22a13 solute carrier family 22 (organic cation transporter), member 13 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLC22A13 mRNA CTD PMID:34925699 NCBI chr 9:119,020,618...119,038,171
Ensembl chr 9:119,022,040...119,038,164
JBrowse link
G Slc22a20 solute carrier family 22 (organic anion transporter), member 20 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLC22A20 mRNA CTD PMID:34925699 NCBI chr19:6,020,262...6,036,171
Ensembl chr19:6,020,262...6,036,171
JBrowse link
G Slc35f3 solute carrier family 35, member F3 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLC35F3 mRNA CTD PMID:34925699 NCBI chr 8:126,865,155...127,122,726
Ensembl chr 8:126,865,734...127,122,717
JBrowse link
G Slc45a2 solute carrier family 45, member 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLC45A2 mRNA CTD PMID:34925699 NCBI chr15:11,000,807...11,029,319
Ensembl chr15:11,000,807...11,029,319
JBrowse link
G Slc6a12 solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLC6A12 mRNA CTD PMID:34925699 NCBI chr 6:121,319,533...121,342,732
Ensembl chr 6:121,320,035...121,342,734
JBrowse link
G Slc6a13 solute carrier family 6 (neurotransmitter transporter, GABA), member 13 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLC6A13 mRNA CTD PMID:34925699 NCBI chr 6:121,277,247...121,314,680
Ensembl chr 6:121,277,186...121,314,692
JBrowse link
G Slc6a20b solute carrier family 6 (neurotransmitter transporter), member 20B affects expression ISO theaflavin-3,3'-digallate affects the expression of SLC6A20 mRNA CTD PMID:34925699 NCBI chr 9:123,422,888...123,461,603
Ensembl chr 9:123,419,865...123,461,630
JBrowse link
G Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLC6A3 mRNA CTD PMID:34925699 NCBI chr13:73,684,270...73,726,791
Ensembl chr13:73,684,866...73,726,791
JBrowse link
G Slc6a4 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLC6A4 mRNA CTD PMID:34925699 NCBI chr11:76,889,423...76,923,169
Ensembl chr11:76,889,429...76,923,166
JBrowse link
G Slc6a7 solute carrier family 6 (neurotransmitter transporter, L-proline), member 7 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLC6A7 mRNA CTD PMID:34925699 NCBI chr18:61,128,448...61,147,484
Ensembl chr18:61,128,452...61,147,294
JBrowse link
G Slco1a5 solute carrier organic anion transporter family, member 1a5 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLCO1A2 mRNA CTD PMID:34925699 NCBI chr 6:142,179,953...142,268,707
Ensembl chr 6:142,179,953...142,268,707
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLCO2B1 mRNA CTD PMID:34925699 NCBI chr 7:99,307,011...99,360,547
Ensembl chr 7:99,307,011...99,360,547
JBrowse link
G Slit1 slit guidance ligand 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLIT1 mRNA CTD PMID:34925699 NCBI chr19:41,586,263...41,735,714
Ensembl chr19:41,588,696...41,732,104
JBrowse link
G Smim23 small integral membrane protein 23 affects expression ISO theaflavin-3,3'-digallate affects the expression of SMIM23 mRNA CTD PMID:34925699 NCBI chr11:32,770,376...32,774,594
Ensembl chr11:32,768,529...32,774,605
JBrowse link
G Sod1 superoxide dismutase 1, soluble multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [Galactose results in decreased expression of SOD1 mRNA] CTD PMID:36638877 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial increases expression ISO theaflavin-3,3'-digallate results in increased expression of SOD2 protein CTD PMID:35847580 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
JBrowse link
G Sostdc1 sclerostin domain containing 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of SOSTDC1 mRNA CTD PMID:34925699 NCBI chr12:36,364,168...36,368,451
Ensembl chr12:36,364,138...36,368,451
JBrowse link
G Sowaha sosondowah ankyrin repeat domain family member A affects expression ISO theaflavin-3,3'-digallate affects the expression of SOWAHA mRNA CTD PMID:34925699 NCBI chr11:53,367,405...53,371,022
Ensembl chr11:53,367,400...53,371,101
JBrowse link
G Sowahb sosondowah ankyrin repeat domain family member B affects expression ISO theaflavin-3,3'-digallate affects the expression of SOWAHB mRNA CTD PMID:34925699 NCBI chr 5:93,188,981...93,192,910
Ensembl chr 5:93,188,982...93,192,881
JBrowse link
G Sox15 SRY (sex determining region Y)-box 15 affects expression ISO theaflavin-3,3'-digallate affects the expression of SOX15 mRNA CTD PMID:34925699 NCBI chr11:69,545,863...69,547,553
Ensembl chr11:69,546,140...69,547,553
JBrowse link
G Sox30 SRY (sex determining region Y)-box 30 affects expression ISO theaflavin-3,3'-digallate affects the expression of SOX30 mRNA CTD PMID:34925699 NCBI chr11:45,869,873...45,908,824
Ensembl chr11:45,871,137...45,908,821
JBrowse link
G Sox9 SRY (sex determining region Y)-box 9 multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of SOX9 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of SOX9 protein] CTD PMID:35847580 NCBI chr11:112,673,036...112,678,583
Ensembl chr11:112,673,050...112,678,586
JBrowse link
G Sp1 trans-acting transcription factor 1 multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased activity of SP1 protein] CTD PMID:12931129 NCBI chr15:102,314,751...102,344,839
Ensembl chr15:102,314,578...102,344,839
JBrowse link
G Sp7 Sp7 transcription factor 7 multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased expression of SP7 protein] CTD PMID:33833684 NCBI chr15:102,265,038...102,275,498
Ensembl chr15:102,265,041...102,275,617
JBrowse link
G Spacdr sperm acrosome developmental regulator affects expression ISO theaflavin-3,3'-digallate affects the expression of SPACDR mRNA CTD PMID:34925699 NCBI chr 5:137,759,963...137,766,715
Ensembl chr 5:137,743,992...137,766,712
JBrowse link
G Spdya speedy/RINGO cell cycle regulator family, member A affects expression ISO theaflavin-3,3'-digallate affects the expression of SPDYA mRNA CTD PMID:34925699 NCBI chr17:71,833,890...71,896,528
Ensembl chr17:71,859,056...71,896,528
JBrowse link
G Spink2 serine peptidase inhibitor, Kazal type 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of SPINK2 mRNA CTD PMID:34925699 NCBI chr 5:77,352,953...77,364,106
Ensembl chr 5:77,352,954...77,359,318
JBrowse link
G Spry4 sprouty RTK signaling antagonist 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of SPRY4 mRNA CTD PMID:34925699 NCBI chr18:38,719,300...38,734,400
Ensembl chr18:38,719,300...38,734,468
JBrowse link
G Spx spexin hormone affects expression ISO theaflavin-3,3'-digallate affects the expression of SPX mRNA CTD PMID:34925699 NCBI chr 6:142,359,114...142,365,466
Ensembl chr 6:142,359,167...142,365,456
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO [Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased expression of SQSTM1 protein CTD PMID:34350509 NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654
JBrowse link
G Src Rous sarcoma oncogene multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in increased phosphorylation of SRC protein] CTD PMID:35903325 NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782
JBrowse link
G Sst somatostatin affects expression ISO theaflavin-3,3'-digallate affects the expression of SST mRNA CTD PMID:34925699 NCBI chr16:23,708,327...23,710,041
Ensembl chr16:23,708,323...23,709,708
JBrowse link
G St8sia6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 affects expression ISO theaflavin-3,3'-digallate affects the expression of ST8SIA6 mRNA CTD PMID:34925699 NCBI chr 2:13,659,745...13,798,659
Ensembl chr 2:13,655,832...13,798,875
JBrowse link
G Stab1 stabilin 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of STAB1 mRNA CTD PMID:34925699 NCBI chr14:30,860,974...30,890,616
Ensembl chr14:30,860,970...30,890,598
JBrowse link
G Stac2 SH3 and cysteine rich domain 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of STAC2 mRNA CTD PMID:34925699 NCBI chr11:97,927,449...97,944,288
Ensembl chr11:97,927,449...97,944,288
JBrowse link
G Stk31 serine threonine kinase 31 affects expression ISO theaflavin-3,3'-digallate affects the expression of STK31 mRNA CTD PMID:34925699 NCBI chr 6:49,372,441...49,446,440
Ensembl chr 6:49,372,538...49,446,435
JBrowse link
G Stk32b serine/threonine kinase 32B affects expression ISO theaflavin-3,3'-digallate affects the expression of STK32B mRNA CTD PMID:34925699 NCBI chr 5:37,604,169...37,874,503
Ensembl chr 5:37,604,169...37,874,515
JBrowse link
G Svopl SV2 related protein homolog (rat)-like affects expression ISO theaflavin-3,3'-digallate affects the expression of SVOPL mRNA CTD PMID:34925699 NCBI chr 6:37,960,674...38,023,944
Ensembl chr 6:37,960,674...38,023,931
JBrowse link
G Sycp2 synaptonemal complex protein 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of SYCP2 mRNA CTD PMID:34925699 NCBI chr 2:177,987,088...178,051,580
Ensembl chr 2:177,987,086...178,049,478
JBrowse link
G Sycp3 synaptonemal complex protein 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of SYCP3 mRNA CTD PMID:34925699 NCBI chr10:88,295,449...88,309,098
Ensembl chr10:88,295,431...88,309,098
JBrowse link
G Syndig1l synapse differentiation inducing 1 like affects expression ISO theaflavin-3,3'-digallate affects the expression of SYNDIG1L mRNA CTD PMID:34925699 NCBI chr12:84,724,051...84,745,720
Ensembl chr12:84,724,051...84,745,605
JBrowse link
G Tac4 tachykinin 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of TAC4 mRNA CTD PMID:34925699 NCBI chr11:95,152,355...95,160,091
Ensembl chr11:95,152,355...95,160,091
JBrowse link
G Tagln transgelin multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in decreased expression of TAGLN protein] CTD PMID:35903325 NCBI chr 9:45,840,926...45,847,356
Ensembl chr 9:45,840,917...45,847,356
JBrowse link
G Tcaf2 TRPM8 channel-associated factor 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of TCAF2 mRNA CTD PMID:34925699 NCBI chr 6:42,599,950...42,622,134
Ensembl chr 6:42,599,950...42,622,188
JBrowse link
G Tead4 TEA domain family member 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of TEAD4 mRNA CTD PMID:34925699 NCBI chr 6:128,204,106...128,277,776
Ensembl chr 6:128,201,251...128,277,786
JBrowse link
G Tecr trans-2,3-enoyl-CoA reductase multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of TECR mRNA] CTD PMID:36105184 NCBI chr 8:84,298,327...84,321,120
Ensembl chr 8:84,298,327...84,334,600
JBrowse link
G Tecta tectorin alpha affects expression ISO theaflavin-3,3'-digallate affects the expression of TECTA mRNA CTD PMID:34925699 NCBI chr 9:42,240,918...42,312,986
Ensembl chr 9:42,240,915...42,311,225
JBrowse link
G Tef thyrotroph embryonic factor affects expression ISO theaflavin-3,3'-digallate affects the expression of TEF mRNA CTD PMID:34925699 NCBI chr15:81,686,874...81,711,064
Ensembl chr15:81,686,622...81,711,064
JBrowse link
G Tex29 testis expressed 29 affects expression ISO theaflavin-3,3'-digallate affects the expression of TEX29 mRNA CTD PMID:34925699 NCBI chr 8:11,890,488...11,905,761
Ensembl chr 8:11,890,474...11,905,761
JBrowse link
G Tll2 tolloid-like 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of TLL2 mRNA CTD PMID:34925699 NCBI chr19:41,069,379...41,199,287
Ensembl chr19:41,071,192...41,195,274
JBrowse link
G Tlr9 toll-like receptor 9 affects expression ISO theaflavin-3,3'-digallate affects the expression of TLR9 mRNA CTD PMID:34925699 NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082
JBrowse link
G Tm7sf2 transmembrane 7 superfamily member 2 multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of TM7SF2 mRNA] CTD PMID:36105184 NCBI chr19:6,112,851...6,117,880
Ensembl chr19:6,112,851...6,118,403
JBrowse link
G Tmem119 transmembrane protein 119 affects expression ISO theaflavin-3,3'-digallate affects the expression of TMEM119 mRNA CTD PMID:34925699 NCBI chr 5:113,931,790...113,938,457
Ensembl chr 5:113,931,790...113,938,577
JBrowse link
G Tmem132e transmembrane protein 132E affects expression ISO theaflavin-3,3'-digallate affects the expression of TMEM132E mRNA CTD PMID:34925699 NCBI chr11:82,279,281...82,338,447
Ensembl chr11:82,279,726...82,337,158
JBrowse link
G Tmem150b transmembrane protein 150B affects expression ISO theaflavin-3,3'-digallate affects the expression of TMEM150B mRNA CTD PMID:34925699 NCBI chr 7:4,709,831...4,728,250
Ensembl chr 7:4,709,831...4,728,248
JBrowse link
G Tmem151a transmembrane protein 151A affects expression ISO theaflavin-3,3'-digallate affects the expression of TMEM151A mRNA CTD PMID:34925699 NCBI chr19:5,120,859...5,135,519
Ensembl chr19:5,120,887...5,135,559
JBrowse link
G Tmem178b transmembrane protein 178B affects expression ISO theaflavin-3,3'-digallate affects the expression of TMEM178B mRNA CTD PMID:34925699 NCBI chr 6:39,848,164...40,232,084
Ensembl chr 6:39,848,395...40,232,084
JBrowse link
G Tmem40 transmembrane protein 40 affects expression ISO theaflavin-3,3'-digallate affects the expression of TMEM40 mRNA CTD PMID:34925699 NCBI chr 6:115,706,092...115,739,427
Ensembl chr 6:115,706,092...115,739,371
JBrowse link
G Tmprss7 transmembrane serine protease 7 affects expression ISO theaflavin-3,3'-digallate affects the expression of TMPRSS7 mRNA CTD PMID:34925699 NCBI chr16:45,476,672...45,521,822
Ensembl chr16:45,476,678...45,514,021
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases secretion
affects expression
EXP
ISO
theaflavin-3,3'-digallate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF mRNA]; theaflavin-3,3'-digallate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of TNF protein]; theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased expression of BGLAP protein]; theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased expression of CTNNB1 protein]; theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased expression of RUNX2 protein]; theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased expression of SP7 protein]; theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased phosphorylation of MAPK1 protein]; theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased phosphorylation of MAPK3 protein]; theaflavin-3,3'-digallate results in decreased expression of and results in decreased secretion of TNF protein
theaflavin-3,3'-digallate results in decreased secretion of TNF protein
theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of TNF mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased secretion of TNF protein]
theaflavin-3,3'-digallate affects the expression of TNF mRNA
CTD PMID:27871911 PMID:30874838 PMID:33833684 PMID:34925699 PMID:35847580 More... NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a, NFKB activator affects expression ISO theaflavin-3,3'-digallate affects the expression of TNFRSF11A mRNA CTD PMID:34925699 NCBI chr 1:105,708,443...105,777,172
Ensembl chr 1:105,708,443...105,775,709
JBrowse link
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 multiple interactions EXP [theaflavin-3,3'-digallate results in increased expression of NFE2L2 protein] inhibits the reaction [TNFSF11 protein results in increased abundance of Reactive Oxygen Species]; theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in decreased expression of CAT mRNA]; theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in decreased expression of GPX1 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in decreased expression of HMOX1 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in decreased expression of NFE2L2 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in increased expression of CD40 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA]; theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in increased expression of MMP9 mRNA] CTD PMID:32694992 NCBI chr14:78,514,886...78,545,483
Ensembl chr14:78,514,885...78,545,483
JBrowse link
G Togaram2 TOG array regulator of axonemal microtubules 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of TOGARAM2 mRNA CTD PMID:34925699 NCBI chr17:71,980,153...72,036,666
Ensembl chr17:71,980,256...72,036,664
JBrowse link
G Trarg1 trafficking regulator of GLUT4 (SLC2A4) 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of TUSC5 mRNA CTD PMID:34925699 NCBI chr11:76,570,699...76,589,490
Ensembl chr11:76,570,634...76,589,490
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of TREM2 mRNA CTD PMID:34925699 NCBI chr17:48,653,429...48,659,304
Ensembl chr17:48,653,429...48,661,175
JBrowse link
G Trim31 tripartite motif-containing 31 affects expression ISO theaflavin-3,3'-digallate affects the expression of TRIM31 mRNA CTD PMID:34925699 NCBI chr17:37,209,022...37,221,109
Ensembl chr17:37,209,010...37,221,106
JBrowse link
G Trim36 tripartite motif-containing 36 affects expression ISO theaflavin-3,3'-digallate affects the expression of TRIM36 mRNA CTD PMID:34925699 NCBI chr18:46,298,367...46,345,674
Ensembl chr18:46,298,367...46,345,674
JBrowse link
G Trim72 tripartite motif-containing 72 affects expression ISO theaflavin-3,3'-digallate affects the expression of TRIM72 mRNA CTD PMID:34925699 NCBI chr 7:127,602,684...127,610,565
Ensembl chr 7:127,603,121...127,610,205
JBrowse link
G Trpm6 transient receptor potential cation channel, subfamily M, member 6 affects expression ISO theaflavin-3,3'-digallate affects the expression of TRPM6 mRNA CTD PMID:34925699 NCBI chr19:18,707,566...18,869,885
Ensembl chr19:18,727,347...18,869,875
JBrowse link
G Trpv5 transient receptor potential cation channel, subfamily V, member 5 affects expression ISO theaflavin-3,3'-digallate affects the expression of TRPV5 mRNA CTD PMID:34925699 NCBI chr 6:41,628,595...41,658,158
Ensembl chr 6:41,629,107...41,657,703
JBrowse link
G Tspo2 translocator protein 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of TSPO2 mRNA CTD PMID:34925699 NCBI chr17:48,754,970...48,758,592
Ensembl chr17:48,754,935...48,758,550
JBrowse link
G Ttc22 tetratricopeptide repeat domain 22 affects expression ISO theaflavin-3,3'-digallate affects the expression of TTC22 mRNA CTD PMID:34925699 NCBI chr 4:106,479,646...106,497,393
Ensembl chr 4:106,479,629...106,497,386
JBrowse link
G Uts2 urotensin 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of UTS2 mRNA CTD PMID:34925699 NCBI chr 4:151,081,554...151,086,267
Ensembl chr 4:151,081,554...151,086,267
JBrowse link
G Vegfa vascular endothelial growth factor A decreases secretion
multiple interactions
ISO theaflavin-3,3'-digallate results in decreased secretion of VEGFA protein
[Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased secretion of VEGFA protein
CTD PMID:34350509 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
G Vil1 villin 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of VIL1 mRNA CTD PMID:34925699 NCBI chr 1:74,448,543...74,474,719
Ensembl chr 1:74,448,535...74,474,718
JBrowse link
G Vsig2 V-set and immunoglobulin domain containing 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of VSIG2 mRNA CTD PMID:34925699 NCBI chr 9:37,450,551...37,455,501
Ensembl chr 9:37,450,551...37,455,501
JBrowse link
G Vsnl1 visinin-like 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of VSNL1 mRNA CTD PMID:34925699 NCBI chr12:11,375,258...11,486,579
Ensembl chr12:11,375,243...11,486,614
JBrowse link
G Vsx2 visual system homeobox 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of VSX2 mRNA CTD PMID:34925699 NCBI chr12:84,616,602...84,642,231
Ensembl chr12:84,616,536...84,642,231
JBrowse link
G Vwa3a von Willebrand factor A domain containing 3A affects expression ISO theaflavin-3,3'-digallate affects the expression of VWA3A mRNA CTD PMID:34925699 NCBI chr 7:120,336,554...120,404,769
Ensembl chr 7:120,338,541...120,404,965
JBrowse link
G Wdr38 WD repeat domain 38 affects expression ISO theaflavin-3,3'-digallate affects the expression of WDR38 mRNA CTD PMID:34925699 NCBI chr 2:38,888,287...38,891,600
Ensembl chr 2:38,887,488...38,896,180
JBrowse link
G Wdr86 WD repeat domain 86 affects expression ISO theaflavin-3,3'-digallate affects the expression of WDR86 mRNA CTD PMID:34925699 NCBI chr 5:24,901,898...24,935,696
Ensembl chr 5:24,916,736...24,935,725
JBrowse link
G Wnt16 wingless-type MMTV integration site family, member 16 affects expression ISO theaflavin-3,3'-digallate affects the expression of WNT16 mRNA CTD PMID:34925699 NCBI chr 6:22,288,179...22,298,521
Ensembl chr 6:22,288,226...22,298,521
JBrowse link
G Wnt6 wingless-type MMTV integration site family, member 6 affects expression ISO theaflavin-3,3'-digallate affects the expression of WNT6 mRNA CTD PMID:34925699 NCBI chr 1:74,793,499...74,824,481
Ensembl chr 1:74,811,051...74,824,481
JBrowse link
G Wnt7a wingless-type MMTV integration site family, member 7A affects expression ISO theaflavin-3,3'-digallate affects the expression of WNT7A mRNA CTD PMID:34925699 NCBI chr 6:91,340,963...91,388,335
Ensembl chr 6:91,340,963...91,388,345
JBrowse link
G Wt1 WT1 transcription factor affects expression ISO theaflavin-3,3'-digallate affects the expression of WT1 mRNA CTD PMID:34925699 NCBI chr 2:104,956,874...105,003,959
Ensembl chr 2:104,956,874...105,003,961
JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions ISO [Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased expression of and results in decreased splicing of XBP1 mRNA; theaflavin-3,3'-digallate results in decreased expression of and results in decreased splicing of XBP1 mRNA CTD PMID:34350509 NCBI chr11:5,470,641...5,475,993
Ensembl chr11:5,470,659...5,475,893
JBrowse link
G Zar1 zygote arrest 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of ZAR1 mRNA CTD PMID:34925699 NCBI chr 5:72,734,457...72,738,427
Ensembl chr 5:72,734,149...72,738,597
JBrowse link
G Zar1l zygote arrest 1-like affects expression ISO theaflavin-3,3'-digallate affects the expression of ZAR1L mRNA CTD PMID:34925699 NCBI chr 5:150,430,520...150,441,659
Ensembl chr 5:150,430,520...150,441,629
JBrowse link
G Zfp385c zinc finger protein 385C affects expression ISO theaflavin-3,3'-digallate affects the expression of ZNF385C mRNA CTD PMID:34925699 NCBI chr11:100,517,045...100,583,292
Ensembl chr11:100,518,369...100,583,281
JBrowse link
G Zfyve28 zinc finger, FYVE domain containing 28 affects expression ISO theaflavin-3,3'-digallate affects the expression of ZFYVE28 mRNA CTD PMID:34925699 NCBI chr 5:34,352,237...34,445,796
Ensembl chr 5:34,352,237...34,445,793
JBrowse link
G Zp2 zona pellucida glycoprotein 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of ZP2 mRNA CTD PMID:34925699 NCBI chr 7:119,725,985...119,744,514
Ensembl chr 7:119,725,995...119,744,514
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22307
    chemical entity 22306
      molecular entity 22302
        polyatomic entity 22158
          heteroatomic molecular entity 22093
            hydroxides 20928
              organic hydroxy compound 19817
                hydroxyflavan 3395
                  catechin 3375
                    Theaflavin 3,3'-digallate 517
Path 2
Term Annotations click to browse term
  CHEBI ontology 22307
    subatomic particle 22302
      composite particle 22302
        hadron 22302
          baryon 22302
            nucleon 22302
              atomic nucleus 22302
                atom 22302
                  main group element atom 22184
                    p-block element atom 22184
                      carbon group element atom 21987
                        carbon atom 21927
                          organic molecular entity 21927
                            organic molecule 21757
                              organic cyclic compound 21385
                                organic heterocyclic compound 20364
                                  oxacycle 18898
                                    benzopyran 12224
                                      1-benzopyran 11984
                                        flavonoid 7305
                                          flavans 3658
                                            hydroxyflavan 3395
                                              catechin 3375
                                                Theaflavin 3,3'-digallate 517
paths to the root