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G |
Ahcy |
adenosylhomocysteinase |
increases hydrolysis |
ISO |
AHCY results in increased hydrolysis of S-Adenosylhomocysteine |
CTD |
PMID:26974671 |
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NCBI chr 3:150,587,833...150,603,057
Ensembl chr 3:150,587,833...150,603,082
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G |
Ahr |
aryl hydrocarbon receptor |
increases abundance multiple interactions |
ISO |
AHR protein results in increased abundance of S-Adenosylhomocysteine PEMT protein promotes the reaction [AHR protein results in increased abundance of S-Adenosylhomocysteine] |
CTD |
PMID:29416063 |
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NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
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G |
Alas2 |
5'-aminolevulinate synthase 2 |
multiple interactions |
ISO |
[S-Adenosylhomocysteine co-treated with Hemin] results in increased expression of ALAS2 mRNA; catechol inhibits the reaction [[S-Adenosylhomocysteine co-treated with Hemin] results in increased expression of ALAS2 mRNA] |
CTD |
PMID:24141029 |
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NCBI chr X:23,167,576...23,187,356
Ensembl chr X:23,167,696...23,187,341
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G |
App |
amyloid beta precursor protein |
increases expression decreases methylation multiple interactions |
ISO |
S-Adenosylhomocysteine results in increased expression of APP protein S-Adenosylhomocysteine results in decreased methylation of APP promoter Betaine inhibits the reaction [S-Adenosylhomocysteine results in decreased methylation of APP promoter]; Betaine inhibits the reaction [S-Adenosylhomocysteine results in increased expression of and results in increased cleavage of APP protein]; S-Adenosylhomocysteine results in increased expression of and results in increased cleavage of APP protein |
CTD |
PMID:19635394 PMID:22064374 |
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NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
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G |
Atp7b |
ATPase copper transporting beta |
increases abundance |
ISO |
ATP7B protein mutant form results in increased abundance of S-Adenosylhomocysteine |
CTD |
PMID:22945834 |
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NCBI chr16:74,865,516...74,944,935
Ensembl chr16:74,865,516...74,945,286
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G |
Bace1 |
beta-secretase 1 |
increases expression |
ISO |
S-Adenosylhomocysteine results in increased expression of BACE1 protein |
CTD |
PMID:19635394 |
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NCBI chr 8:50,140,092...50,162,388
Ensembl chr 8:50,139,997...50,162,361
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G |
Col1a1 |
collagen type I alpha 1 chain |
decreases expression |
ISO |
S-Adenosylhomocysteine results in decreased expression of COL1A1 mRNA |
CTD |
PMID:15983038 |
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NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
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G |
Col1a2 |
collagen type I alpha 2 chain |
decreases expression |
ISO |
S-Adenosylhomocysteine results in decreased expression of COL1A2 mRNA |
CTD |
PMID:15983038 |
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NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
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G |
Comt |
catechol-O-methyltransferase |
decreases activity |
EXP |
S-Adenosylhomocysteine results in decreased activity of COMT protein |
CTD |
PMID:10064789 |
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NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
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G |
Dnmt1 |
DNA methyltransferase 1 |
decreases activity multiple interactions |
ISO |
S-Adenosylhomocysteine results in decreased activity of DNMT1 protein S-Adenosylhomocysteine inhibits the reaction [DNMT1 protein binds to OGG1 promoter] |
CTD |
PMID:16037419 PMID:22064374 |
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NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
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G |
Fgf19 |
fibroblast growth factor 19 |
decreases abundance |
ISO |
FGF19 protein results in decreased abundance of S-Adenosylhomocysteine |
CTD |
PMID:29416063 |
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NCBI chr 1:218,058,405...218,061,693
Ensembl chr 1:218,058,405...218,061,693
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G |
Hbb |
hemoglobin subunit beta |
multiple interactions |
ISO |
[S-Adenosylhomocysteine co-treated with Hemin] results in increased expression of HBB mRNA; catechol inhibits the reaction [[S-Adenosylhomocysteine co-treated with Hemin] results in increased expression of HBB mRNA] |
CTD |
PMID:24141029 |
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NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725
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G |
Hmbs |
hydroxymethylbilane synthase |
multiple interactions |
ISO |
[S-Adenosylhomocysteine co-treated with Hemin] results in increased expression of HMBS mRNA; catechol inhibits the reaction [[S-Adenosylhomocysteine co-treated with Hemin] results in increased expression of HMBS mRNA] |
CTD |
PMID:24141029 |
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NCBI chr 8:48,667,278...48,674,673
Ensembl chr 8:48,667,275...48,674,748
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G |
Mmp2 |
matrix metallopeptidase 2 |
increases expression multiple interactions |
ISO EXP |
S-Adenosylhomocysteine results in increased expression of MMP2 mRNA; S-Adenosylhomocysteine results in increased expression of MMP2 protein S-Adenosylhomocysteine promotes the reaction [SP1 protein binds to MMP2 promoter] U 0126 inhibits the reaction [S-Adenosylhomocysteine results in increased expression of MMP2 protein] |
CTD |
PMID:19770485 |
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NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
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G |
Nfkbia |
NFKB inhibitor alpha |
decreases expression |
EXP |
S-Adenosylhomocysteine results in decreased expression of NFKBIA protein |
CTD |
PMID:19770485 |
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NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
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G |
Nr0b2 |
nuclear receptor subfamily 0, group B, member 2 |
decreases abundance |
ISO |
NR0B2 protein results in decreased abundance of S-Adenosylhomocysteine |
CTD |
PMID:29416063 |
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NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
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G |
Ogg1 |
8-oxoguanine DNA glycosylase |
multiple interactions decreases methylation decreases expression |
ISO |
Betaine inhibits the reaction [S-Adenosylhomocysteine results in decreased expression of OGG1 protein]; Betaine inhibits the reaction [S-Adenosylhomocysteine results in decreased methylation of OGG1 promoter]; S-Adenosylhomocysteine inhibits the reaction [DNMT1 protein binds to OGG1 promoter] S-Adenosylhomocysteine results in decreased expression of OGG1 mRNA; S-Adenosylhomocysteine results in decreased expression of OGG1 protein |
CTD |
PMID:22064374 |
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NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326
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G |
Pemt |
phosphatidylethanolamine N-methyltransferase |
multiple interactions |
ISO |
PEMT protein promotes the reaction [AHR protein results in increased abundance of S-Adenosylhomocysteine] |
CTD |
PMID:29416063 |
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NCBI chr10:46,339,821...46,404,640
Ensembl chr10:46,339,821...46,404,642
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
increases expression |
ISO |
S-Adenosylhomocysteine results in increased expression of PPARGC1A mRNA |
CTD |
PMID:23056435 |
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NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
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G |
Psen1 |
presenilin 1 |
multiple interactions decreases methylation increases expression |
ISO |
Betaine inhibits the reaction [S-Adenosylhomocysteine results in decreased methylation of PSEN1 promoter] S-Adenosylhomocysteine results in increased expression of PSEN1 protein |
CTD |
PMID:19635394 |
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NCBI chr 6:107,169,514...107,221,000
Ensembl chr 6:107,169,528...107,216,798
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G |
Slc19a1 |
solute carrier family 19 member 1 |
affects abundance |
ISO |
SLC19A1 protein affects the abundance of S-Adenosylhomocysteine |
CTD |
PMID:15705887 |
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NCBI chr20:12,334,675...12,354,517
Ensembl chr20:12,334,676...12,352,377
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G |
Sp1 |
Sp1 transcription factor |
multiple interactions |
EXP |
S-Adenosylhomocysteine promotes the reaction [SP1 protein binds to MMP2 promoter] |
CTD |
PMID:19770485 |
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NCBI chr 7:144,014,173...144,044,635
Ensembl chr 7:144,014,173...144,044,629
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G |
Timp2 |
TIMP metallopeptidase inhibitor 2 |
decreases expression |
ISO |
S-Adenosylhomocysteine results in decreased expression of TIMP2 protein |
CTD |
PMID:19770485 |
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NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072
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