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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:N-(2,6-diethylphenyl)-2-chloroacetamide
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Accession:CHEBI:136492 term browser browse the term
Definition:An aromatic amide obtained by formal condensation of the carboxy group of chloroacetic acid with the amnio group of 2,6-diethylaniline.
Synonyms:related_synonym: 2-Chloro-2',6'-diethylacetanilide;   2-chloro-N-(2,6-diethylphenyl)-acetamide;   Formula=C12H16ClNO;   InChI=1S/C12H16ClNO/c1-3-9-6-5-7-10(4-2)12(9)14-11(15)8-13/h5-7H,3-4,8H2,1-2H3,(H,14,15);   InChIKey=LBJVHMAYBNQJBK-UHFFFAOYSA-N;   N-2'-Chloroacetyl-2,6-diethylaniline;   SMILES=C1=CC=C(C(=C1CC)NC(CCl)=O)CC;   alpha-chloro-2',6'-diethylacetanilide
 xref: AGR:IND20374250;   AGR:IND20602966;   AGR:IND92053545;   CAS:6967-29-9;   HMDB:HMDB0032855
 xref_mesh: MESH:C093872
 xref: MetaCyc:CPD-18945;   PMID:10475613;   PMID:10552745;   PMID:11057589;   PMID:11133395;   PMID:11863300;   PMID:17207564;   PMID:18273908;   PMID:24928877;   PMID:26368393;   PMID:7766803;   PMID:9528697;   Reaxys:2111384



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N-(2,6-diethylphenyl)-2-chloroacetamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases chemical synthesis
increases abundance
multiple interactions
ISO CYP3A4 protein results in increased chemical synthesis of 2-chloro-N-(2,6-diethylphenyl)acetamide
CYP3A4 protein results in increased abundance of 2-chloro-N-(2,6-diethylphenyl)acetamide
[CYP3A4 protein results in increased metabolism of alachlor] which results in increased abundance of 2-chloro-N-(2,6-diethylphenyl)acetamide
CTD PMID:10475613 PMID:18273908 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
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Term Annotations click to browse term
  CHEBI ontology 19808
    role 19757
      biological role 19757
        aetiopathogenetic role 19032
          genotoxin 17472
            N-(2,6-diethylphenyl)-2-chloroacetamide 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19807
      composite particle 19807
        hadron 19807
          baryon 19807
            nucleon 19807
              atomic nucleus 19807
                atom 19807
                  main group element atom 19704
                    p-block element atom 19704
                      carbon group element atom 19626
                        carbon atom 19616
                          organic molecular entity 19616
                            organic group 18725
                              organic divalent group 18716
                                organodiyl group 18716
                                  carbonyl group 18664
                                    carbonyl compound 18664
                                      carboxylic acid 18361
                                        monocarboxylic acid 17631
                                          acetic acid 10853
                                            haloacetic acid 53
                                              chloroacetic acid 29
                                                N-(2,6-diethylphenyl)-2-chloroacetamide 1
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