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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:anagliptin
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Accession:CHEBI:136043 term browser browse the term
Synonyms:related_synonym: Formula=C19H25N7O2;   InChI=1S/C19H25N7O2/c1-13-7-16-21-9-14(11-26(16)24-13)18(28)22-12-19(2,3)23-10-17(27)25-6-4-5-15(25)8-20/h7,9,11,15,23H,4-6,10,12H2,1-3H3,(H,22,28)/t15-/m0/s1;   InChIKey=LDXYBEHACFJIEL-HNNXBMFYSA-N;   SMILES=C1=C(C=NC=2N1N=C(C2)C)C(NCC(NCC(N3[C@@H](CCC3)C#N)=O)(C)C)=O;   anagliptin HCl;   anagliptin hydrochloride;   beskoa;   suiny
 xref: CAS:739366-20-2;   Drug_Central:4896
 xref_mesh: MESH:C583175


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anagliptin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO anagliptin inhibits the reaction [Hydrogen Peroxide results in increased expression of CCL2 mRNA] CTD PMID:31586451 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ctsk cathepsin K multiple interactions ISO anagliptin inhibits the reaction [Hydrogen Peroxide results in increased expression of CTSK mRNA] CTD PMID:31586451 NCBI chr 2:196,655,469...196,666,447
Ensembl chr 2:196,655,469...196,666,446
JBrowse link
G Ctss cathepsin S multiple interactions ISO anagliptin inhibits the reaction [Hydrogen Peroxide results in increased expression of CTSS mRNA] CTD PMID:31586451 NCBI chr 2:197,655,780...197,679,768
Ensembl chr 2:197,655,786...197,679,458
JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions ISO anagliptin inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBA mRNA] CTD PMID:31586451 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions ISO anagliptin inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBB mRNA] CTD PMID:31586451 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547
JBrowse link
G Dpp4 dipeptidylpeptidase 4 decreases activity ISO anagliptin results in decreased activity of DPP4 protein CTD PMID:31586451 NCBI chr 3:48,291,055...48,372,672
Ensembl chr 3:48,291,055...48,372,672
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO anagliptin inhibits the reaction [Hydrogen Peroxide results in increased expression of ICAM1 mRNA] CTD PMID:31586451 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO anagliptin inhibits the reaction [Hydrogen Peroxide results in increased expression of MMP2 mRNA] CTD PMID:31586451 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO anagliptin inhibits the reaction [Hydrogen Peroxide results in increased expression of MMP9 mRNA] CTD PMID:31586451 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [anagliptin inhibits the reaction [Hydrogen Peroxide results in decreased expression of NOS3 protein]]; anagliptin inhibits the reaction [Hydrogen Peroxide results in decreased expression of NOS3 mRNA]; anagliptin inhibits the reaction [Hydrogen Peroxide results in decreased expression of NOS3 protein] CTD PMID:31586451 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO anagliptin inhibits the reaction [Hydrogen Peroxide results in increased expression of VCAM1 mRNA] CTD PMID:31586451 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    chemical entity 19770
      atom 19768
        nonmetal atom 19651
          nitrogen atom 18582
            nitrogen molecular entity 18582
              organonitrogen compound 18370
                carboxamide 17208
                  amino acid amide 890
                    anagliptin 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19662
                    p-block element atom 19662
                      carbon group element atom 19580
                        carbon atom 19571
                          organic molecular entity 19571
                            organic group 18602
                              organic divalent group 18593
                                organodiyl group 18593
                                  carbonyl group 18506
                                    carbonyl compound 18506
                                      carboxylic acid 18158
                                        carboacyl group 17412
                                          univalent carboacyl group 17412
                                            carbamoyl group 17208
                                              carboxamide 17208
                                                amino acid amide 890
                                                  anagliptin 11
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