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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:dapoxetine
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Accession:CHEBI:135962 term browser browse the term
Synonyms:related_synonym: Formula=C21H23NO;   InChI=1S/C21H23NO/c1-22(2)20(18-10-4-3-5-11-18)15-16-23-21-14-8-12-17-9-6-7-13-19(17)21/h3-14,20H,15-16H2,1-2H3/t20-/m0/s1;   InChIKey=USRHYDPUVLEVMC-FQEVSTJZSA-N;   LY-210448;   SMILES=O(CC[C@H](N(C)C)C1=CC=CC=C1)C=2C3=C(C=CC2)C=CC=C3;   dapoxetine hydrochloride;   priligy
 xref: CAS:119356-77-3;   Drug_Central:4381
 xref_mesh: MESH:C080598

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dapoxetine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions EXP dapoxetine inhibits the reaction [Testosterone results in increased expression of AR mRNA] CTD PMID:27687055 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP dapoxetine inhibits the reaction [Testosterone results in decreased expression of BAX protein] CTD PMID:27687055 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP dapoxetine inhibits the reaction [Testosterone results in increased expression of BCL2 protein] CTD PMID:27687055 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Casp3 caspase 3 multiple interactions EXP dapoxetine inhibits the reaction [Testosterone results in decreased expression of CASP3 protein modified form] CTD PMID:27687055 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP dapoxetine inhibits the reaction [Testosterone results in increased expression of NOS2 protein] CTD PMID:27687055 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP dapoxetine inhibits the reaction [Testosterone results in increased expression of PCNA mRNA] CTD PMID:27687055 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP dapoxetine inhibits the reaction [Testosterone results in increased expression of PTGS2 protein] CTD PMID:27687055 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP dapoxetine inhibits the reaction [Testosterone results in increased expression of TNF protein] CTD PMID:27687055 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19853
    chemical entity 19853
      molecular entity 19851
        polyatomic entity 19765
          molecule 19600
            cyclic compound 19417
              bicyclic compound 16926
                carbobicyclic compound 5807
                  naphthalenes 3750
                    dapoxetine 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19853
    subatomic particle 19851
      composite particle 19851
        hadron 19851
          baryon 19851
            nucleon 19851
              atomic nucleus 19851
                atom 19851
                  main group element atom 19744
                    p-block element atom 19744
                      carbon group element atom 19650
                        carbon atom 19639
                          organic molecular entity 19639
                            organic molecule 19568
                              organic cyclic compound 19378
                                carbocyclic compound 18284
                                  carbopolycyclic compound 17043
                                    carbobicyclic compound 5807
                                      naphthalenes 3750
                                        dapoxetine 8
paths to the root