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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:vernakalant
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Accession:CHEBI:135956 term browser browse the term
Synonyms:related_synonym: Formula=C20H31NO4;   InChI=1S/C20H31NO4/c1-23-19-8-7-15(13-20(19)24-2)10-12-25-18-6-4-3-5-17(18)21-11-9-16(22)14-21/h7-8,13,16-18,22H,3-6,9-12,14H2,1-2H3/t16-,17-,18-/m1/s1;   InChIKey=VBHQKCBVWWUUKN-KZNAEPCWSA-N;   RSD1235;   SMILES=O(CCC1=CC(OC)=C(C=C1)OC)[C@H]2[C@@H](CCCC2)N3CC[C@H](C3)O;   brinavess;   vernakalant HCl;   vernakalant hydrochloride
 xref: CAS:794466-70-9;   Drug_Central:4365
 xref_mesh: MESH:C524581



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vernakalant term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases metabolic processing ISO CYP2D6 protein results in increased metabolism of vernakalant CTD PMID:18927241 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 affects binding
multiple interactions
ISO vernakalant binds to KCNA5 protein
vernakalant binds to and results in decreased activity of KCNA5 protein
CTD PMID:17872968 PMID:19713139 NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20057
    chemical entity 20068
      molecular entity 20056
        polyatomic entity 19987
          heteroatomic molecular entity 19923
            hydroxides 19434
              organic hydroxy compound 19001
                alcohol 15182
                  vernakalant 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 20057
    subatomic particle 20056
      composite particle 20068
        hadron 20056
          baryon 20056
            nucleon 20056
              atomic nucleus 20056
                atom 20056
                  main group element atom 19971
                    p-block element atom 19971
                      carbon group element atom 19889
                        carbon atom 19894
                          organic molecular entity 19882
                            organic molecule 19830
                              organic cyclic compound 19603
                                organic aromatic compound 19444
                                  phenols 18667
                                    vernakalant 2
paths to the root