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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:migalastat
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Accession:CHEBI:135923 term browser browse the term
Synonyms:related_synonym: 1-Deoxygalactonojirimycin;   1-Deoxygalactonojirimycin hydrochloride;   Formula=C6H13NO4;   GR181413A;   InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5+,6-/m1/s1;   InChIKey=LXBIFEVIBLOUGU-DPYQTVNSSA-N;   SMILES=[C@H]1([C@H]([C@H]([C@H](NC1)CO)O)O)O;   galafold;   migalastat HCl;   migalastat hydrochloride
 xref: CAS:108147-54-2;   Drug_Central:5110
 xref_mesh: MESH:C090092


show annotations for term's descendants           Sort by:
migalastat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gla galactosidase, alpha multiple interactions ISO [GLA protein mutant form binds to GLA protein mutant form] which results in decreased susceptibility to migalastat CTD PMID:22773828 NCBI chr  X:97,769,227...97,780,646
Ensembl chr  X:97,768,996...97,780,664 		JBrowse link
G Lct lactase decreases activity
multiple interactions		 EXP migalastat results in decreased activity of LCT protein
[migalastat results in decreased activity of LCT protein] which results in decreased hydrolysis of isoquercitrin; [migalastat results in decreased activity of LCT protein] which results in decreased hydrolysis of spiraeoside; [migalastat results in decreased activity of LCT protein] which results in decreased uptake of Quercetin		 CTD PMID:12663055 NCBI chr13:39,781,929...39,824,456
Ensembl chr13:39,781,929...39,824,456 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19932
    chemical entity 19930
      atom 19930
        nonmetal atom 19859
          nitrogen atom 19024
            nitrogen molecular entity 19024
              organonitrogen compound 18871
                organonitrogen heterocyclic compound 18179
                  piperidines 7750
                    migalastat 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19932
    subatomic particle 19930
      composite particle 19930
        hadron 19930
          baryon 19930
            nucleon 19930
              atomic nucleus 19930
                atom 19930
                  main group element atom 19876
                    p-block element atom 19876
                      carbon group element atom 19816
                        carbon atom 19812
                          organic molecular entity 19812
                            organic molecule 19764
                              organic cyclic compound 19553
                                organic heterocyclic compound 18905
                                  organic heteromonocyclic compound 17827
                                    piperidines 7750
                                      migalastat 2
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