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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:methylprednisolone succinate
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Accession:CHEBI:135765 term browser browse the term
Synonyms:related_synonym: Formula=C26H34O8;   InChI=1S/C26H34O8/c1-14-10-16-17-7-9-26(33,20(29)13-34-22(32)5-4-21(30)31)25(17,3)12-19(28)23(16)24(2)8-6-15(27)11-18(14)24/h6,8,11,14,16-17,19,23,28,33H,4-5,7,9-10,12-13H2,1-3H3,(H,30,31)/t14-,16-,17-,19-,23+,24-,25-,26-/m0/s1;   InChIKey=IMBXEJJVJRTNOW-XYMSELFBSA-N;   SMILES=C[C@@]12[C@]([C@]3([C@]([C@H](C1)O)([C@]4(C)C([C@H](C3)C)=CC(C=C4)=O)[H])[H])(CC[C@@]2(C(COC(CCC(O)=O)=O)=O)O)[H];   methylprednisolone hemisuccinate;   methylprednisolone sodium succinate
 xref: CAS:2921-57-5;   Drug_Central:1771
 xref_mesh: MESH:D008776


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methylprednisolone succinate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ces2h carboxylesterase 2H multiple interactions
increases hydrolysis
EXP Dexamethasone promotes the reaction [CES2 protein results in increased hydrolysis of Methylprednisolone Hemisuccinate] CTD PMID:15794950 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
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  CHEBI ontology 19877
    role 19827
      biological role 19827
        molecular messenger 18309
          hormone 18060
            steroid hormone 7796
              corticosteroid hormone 5256
                methylprednisolone succinate 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19877
    subatomic particle 19875
      composite particle 19875
        hadron 19875
          baryon 19875
            nucleon 19875
              atomic nucleus 19875
                atom 19875
                  main group element atom 19765
                    p-block element atom 19765
                      carbon group element atom 19670
                        carbon atom 19659
                          organic molecular entity 19659
                            organic group 18571
                              organic divalent group 18562
                                organodiyl group 18562
                                  carbonyl group 18471
                                    carbonyl compound 18471
                                      dicarboxylic acids and O-substituted derivatives 10302
                                        dicarboxylic acid 10294
                                          alpha,omega-dicarboxylic acid 2784
                                            succinic acid 220
                                              succinate ester 111
                                                hemisuccinate 107
                                                  methylprednisolone succinate 1
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