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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:prednisolone succinate
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Accession:CHEBI:135745 term browser browse the term
Definition:A hemisuccinate resulting from the formal condensation of the 21-hydroxy group prednisolone with one of the carboxy groups of succinic acid. It is used to treat mild to moderate non-infectious eye allergies and inflammation, including damage caused by chemical and thermal burns.
Synonyms:exact_synonym: 4-[(11beta,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl)oxy]-4-oxobutanoic acid
 related_synonym: 11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione 21-hemisuccinate;   Delta(1)-hydrocortisone 21-hemisuccinate;   Delta(1)-hydrocortisone succinate;   Formula=C25H32O8;   InChI=1S/C25H32O8/c1-23-9-7-15(26)11-14(23)3-4-16-17-8-10-25(32,24(17,2)12-18(27)22(16)23)19(28)13-33-21(31)6-5-20(29)30/h7,9,11,16-18,22,27,32H,3-6,8,10,12-13H2,1-2H3,(H,29,30)/t16-,17-,18-,22+,23-,24-,25-/m0/s1;   InChIKey=APGDTXUMTIZLCJ-CGVGKPPMSA-N;   Prednisolut;   SMILES=[H][C@@]12CC[C@](O)(C(=O)COC(=O)CCC(O)=O)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C=C[C@]12C;   prednisolone 21-(hydrogen succinate);   prednisolone 21-hemisuccinate;   prednisolone 21-succinate;   prednisolone bisuccinate;   prednisolone hemisuccinate
 xref: CAS:2920-86-7;   DrugBank:DB14633;   Drug_Central:2246;   KEGG:D02156;   LINCS:LSM-36396;   PMID:1029643;   PMID:10959575;   PMID:11446168;   PMID:1235505;   PMID:13371916;   PMID:13439215;   PMID:13704303;   PMID:13822491;   PMID:14483331;   PMID:2253583;   PMID:29175410;   PMID:3213042;   PMID:3441354;   PMID:3580023;   PMID:3964328;   PMID:3994138;   PMID:4084667;   PMID:4433653
 cyclic_relationship: is_conjugate_acid_of CHEBI:157677

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  CHEBI ontology 19875
    role 19825
      application 19494
        anti-inflammatory agent 14992
          anti-inflammatory drug 13635
            prednisolone succinate 0
Path 2
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  CHEBI ontology 19875
    subatomic particle 19873
      composite particle 19873
        hadron 19873
          baryon 19873
            nucleon 19873
              atomic nucleus 19873
                atom 19873
                  main group element atom 19763
                    p-block element atom 19763
                      carbon group element atom 19668
                        carbon atom 19657
                          organic molecular entity 19657
                            organic group 18569
                              organic divalent group 18560
                                organodiyl group 18560
                                  carbonyl group 18468
                                    carbonyl compound 18468
                                      ketone 16216
                                        oxo steroid 9298
                                          3-oxo steroid 8828
                                            3-oxo-Delta(4) steroid 7957
                                              progesterone 2715
                                                Delta(1)-progesterone 238
                                                  prednisolone 233
                                                    prednisolone succinate 0
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