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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:sivelestat
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Accession:CHEBI:135704 term browser browse the term
Synonyms:related_synonym: Formula=C20H22N2O7S;   InChI=1S/C20H22N2O7S/c1-20(2,3)19(26)29-13-8-10-14(11-9-13)30(27,28)22-16-7-5-4-6-15(16)18(25)21-12-17(23)24/h4-11,22H,12H2,1-3H3,(H,21,25)(H,23,24);   InChIKey=BTGNGJJLZOIYID-UHFFFAOYSA-N;   SMILES=C(NCC(O)=O)(=O)C1=C(NS(=O)(=O)C2=CC=C(C=C2)OC(C(C)(C)C)=O)C=CC=C1
 xref: CAS:127373-66-4;   Drug_Central:2452
 xref_mesh: MESH:C069195



show annotations for term's descendants           Sort by:
sivelestat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Elane elastase, neutrophil expressed decreases activity EXP sivelestat results in decreased activity of ELANE protein CTD PMID:19088179 NCBI chr10:79,722,146...79,724,050
Ensembl chr10:79,722,081...79,724,049
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22178
    role 22194
      biological role 22162
        poison 19423
          toxin 16246
            uremic toxin 98
              N-benzoylglycine 6
                sivelestat 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 22178
    subatomic particle 22170
      composite particle 22170
        hadron 22201
          baryon 22170
            nucleon 22170
              atomic nucleus 22170
                atom 22170
                  main group element atom 22104
                    main group molecular entity 22104
                      s-block molecular entity 21729
                        hydrogen molecular entity 21646
                          hydrides 20758
                            inorganic hydride 18672
                              pnictogen hydride 18652
                                nitrogen hydride 18519
                                  azane 18426
                                    ammonia 18425
                                      organic amino compound 18425
                                        amino acid 16428
                                          alpha-amino acid 14205
                                            L-alpha-amino acid 13317
                                              serine family amino acid 5536
                                                glycine 3046
                                                  glycine derivative 3036
                                                    N-acylglycine 29
                                                      N-benzoylglycine 6
                                                        sivelestat 1
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