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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:cloricromen
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Accession:CHEBI:135628 term browser browse the term
Synonyms:related_synonym: AD6;   Formula=C20H26ClNO5;   InChI=1S/C20H26ClNO5/c1-5-22(6-2)11-10-15-13(4)14-8-9-16(26-12-17(23)25-7-3)18(21)19(14)27-20(15)24/h8-9H,5-7,10-12H2,1-4H3;   InChIKey=GYNNRVJJLAVVTQ-UHFFFAOYSA-N;   SMILES=CC=1C=2C(=C(Cl)C(=CC2)OCC(OCC)=O)OC(C1CCN(CC)CC)=O;   cloricromen hydrochloride;   cloricromene;   proendotel
 xref: CAS:68206-94-0;   Drug_Central:713
 xref_mesh: MESH:C025945


show annotations for term's descendants           Sort by:
cloricromen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Icam1 intercellular adhesion molecule 1 multiple interactions EXP cloricromen inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein] CTD PMID:19279317 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP cloricromen inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] CTD PMID:15322736 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions EXP cloricromen inhibits the reaction [Streptozocin results in increased expression of NOS3 protein] CTD PMID:19279317 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression		 EXP cloricromen inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; cloricromen inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; cloricromen inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; cloricromen inhibits the reaction [Streptozocin results in increased expression of TNF protein]
cloricromen results in decreased expression of TNF protein		 CTD PMID:11343695 PMID:15322736 PMID:16572308 PMID:19279317 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP cloricromen inhibits the reaction [Streptozocin results in increased expression of VEGFA protein] CTD PMID:19279317 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19831
    chemical entity 19829
      molecular entity 19829
        polyatomic entity 19787
          molecule 19692
            cyclic compound 19508
              aromatic compound 19359
                organic aromatic compound 19359
                  phenylpropanoid 11285
                    coumarins 4143
                      cloricromen 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19831
    subatomic particle 19829
      composite particle 19829
        hadron 19829
          baryon 19829
            nucleon 19829
              atomic nucleus 19829
                atom 19829
                  main group element atom 19779
                    p-block element atom 19779
                      carbon group element atom 19728
                        carbon atom 19724
                          organic molecular entity 19724
                            organic molecule 19677
                              organic cyclic compound 19490
                                organic heterocyclic compound 18852
                                  oxacycle 17838
                                    benzopyran 11965
                                      1-benzopyran 11716
                                        chromenes 4420
                                          chromenone 4372
                                            coumarins 4143
                                              cloricromen 5
paths to the root